Rap2b

Summary

Gene Symbol: Rap2b
Description: RAP2B, member of RAS oncogene family
Alias: 4021402C18Rik, AA408554, ras-related protein Rap-2b
Species: mouse

Top Publications

  1. pmc Rap2B promotes proliferation, migration, and invasion of human breast cancer through calcium-related ERK1/2 signaling pathway
    Jiehui Di
    1 Cancer Institute, Xuzhou Medical College, Xuzhou 221002, Jiangsu, P R China 2 Department of Radiation Oncology and Lineberger Comprehensive Cancer Center, School of Medicine, The University of North Carolina at Chapel Hill, 101 Manning Drive, Chapel Hill, NC 27514, USA
    Sci Rep 5:12363. 2015
  2. ncbi Crystal structure of the RUN domain of the RAP2-interacting protein x
    Mutsuko Kukimoto-Niino
    RIKEN Genomic Sciences Center, Yokohama 230 0045, Japan
    J Biol Chem 281:31843-53. 2006
  3. doi Rap2 function requires palmitoylation and recycling endosome localization
    Yukiko Uechi
    Division of Cell Biology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
    Biochem Biophys Res Commun 378:732-7. 2009

Detail Information

Publications3

  1. pmc Rap2B promotes proliferation, migration, and invasion of human breast cancer through calcium-related ERK1/2 signaling pathway
    Jiehui Di
    1 Cancer Institute, Xuzhou Medical College, Xuzhou 221002, Jiangsu, P R China 2 Department of Radiation Oncology and Lineberger Comprehensive Cancer Center, School of Medicine, The University of North Carolina at Chapel Hill, 101 Manning Drive, Chapel Hill, NC 27514, USA
    Sci Rep 5:12363. 2015
    b>Rap2B, a member of GTP-binding proteins, is widely upregulated in many types of tumors and promotes migration and invasion of human suprarenal epithelioma. However, the function of Rap2B in breast cancer is unknown...
  2. ncbi Crystal structure of the RUN domain of the RAP2-interacting protein x
    Mutsuko Kukimoto-Niino
    RIKEN Genomic Sciences Center, Yokohama 230 0045, Japan
    J Biol Chem 281:31843-53. 2006
    ..This fragment, the RPIPx RUN domain, interacted specifically with Rap2B in vitro in a nucleotide-dependent manner. The crystal structure of the RPIPx RUN domain was determined at 2...
  3. doi Rap2 function requires palmitoylation and recycling endosome localization
    Yukiko Uechi
    Division of Cell Biology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
    Biochem Biophys Res Commun 378:732-7. 2009
    Rap2A, Rap2B, and Rap2C are Ras-like small G proteins. The role of their post-translational processing has not been investigated due to the lack of information on their downstream signaling...