Rab20

Summary

Gene Symbol: Rab20
Description: RAB20, member RAS oncogene family
Alias: AA536966, D8Ertd350e, ras-related protein Rab-20
Species: mouse

Top Publications

  1. ncbi Cloning and subcellular localization of novel rab proteins reveals polarized and cell type-specific expression
    A Lutcke
    European Molecular Biology Laboratory, Heidelberg, FRG
    J Cell Sci 107:3437-48. 1994
  2. doi Inpp5e increases the Rab5 association and phosphatidylinositol 3-phosphate accumulation at the phagosome through an interaction with Rab20
    Tomohiro Segawa
    Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734 8553, Japan
    Biochem J 464:365-75. 2014
  3. pmc Rab20 regulates phagosome maturation in RAW264 macrophages during Fc gamma receptor-mediated phagocytosis
    Youhei Egami
    Department of Histology and Cell Biology, School of Medicine, Kagawa University, Miki, Kagawa, Japan
    PLoS ONE 7:e35663. 2012
  4. doi Expression profiling of Rab GTPases reveals the involvement of Rab20 and Rab32 in acute brain inflammation in mice
    Yajie Liang
    Department of Neurobiology, Third Military Medical University, Chongqing 400038, PR China
    Neurosci Lett 527:110-4. 2012
  5. ncbi The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach
    P Chavrier
    Cell Biology Programme, European Molecular Biology Laboratory, Heidelberg, F R G
    Gene 112:261-4. 1992
  6. ncbi Expression of Rab proteins during mouse embryonic development
    C Murphy
    Cell Biology Program, European Molecular Biology Laboratory, Heidelberg, Germany
    Methods Enzymol 257:324-32. 1995
  7. ncbi Genetic mapping of Rab20 on mouse chromosome 8
    E B McMurtrie
    Department of Medicine, University of Florida, Gainesville, Florida 32610 0221, USA
    Mamm Genome 8:291-2. 1997
  8. ncbi A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34
    Kalyani R Vats
    Department of Pediatrics, Division of Pediatric Nephrology, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Am Soc Nephrol 17:1158-67. 2006
  9. doi The GTPase RAB20 is a HIF target with mitochondrial localization mediating apoptosis in hypoxia
    Thomas Hackenbeck
    University of Erlangen Nuremberg, Erlangen, Germany
    Biochim Biophys Acta 1813:1-13. 2011

Scientific Experts

  • Yajie Liang
  • Tomohiro Segawa
  • Youhei Egami
  • Thomas Hackenbeck
  • Kalyani R Vats
  • Shunsuke Takasuga
  • Kaoru Hazeki
  • Ying Guo
  • Kiyomi Nigorikawa
  • Osamu Hazeki
  • Shin Morioka
  • Ken Asanuma
  • Nobukazu Araki
  • Xiaoqing Wu
  • Juliana Monti
  • Ruth Schietke
  • Bernd Klanke
  • Udo Gaipl
  • Christina Warnecke
  • Regina Huber
  • Didier Ferbus
  • Benjamin Frey
  • Karl X Knaup
  • Gerard Goubin
  • Bernd Wullich
  • Michael S Wiesener
  • Kai Uwe Eckardt
  • M Zerial
  • Urvashi Surti
  • Ashutosh Vats
  • Abhay N Vats
  • Donald R Frederick
  • Chandra Ishwad
  • Michael Moritz
  • Demetrius Ellis
  • Ish Singla
  • Robert Ferrell
  • Parul Jayakar
  • C Murphy
  • E B McMurtrie
  • A Lutcke
  • S F Kingsmore
  • - Barbosa MDFS
  • K Simons
  • P Dupree
  • V M Olkkonen
  • R G Parton
  • P Chavrier
  • A Valencia

Detail Information

Publications9

  1. ncbi Cloning and subcellular localization of novel rab proteins reveals polarized and cell type-specific expression
    A Lutcke
    European Molecular Biology Laboratory, Heidelberg, FRG
    J Cell Sci 107:3437-48. 1994
    ..in different tissues and the intracellular localization in organ cryosections of two rab proteins, rab18 and rab20. Both northern blot analysis and confocal immunofluorescence microscopy demonstrated that these proteins are ..
  2. doi Inpp5e increases the Rab5 association and phosphatidylinositol 3-phosphate accumulation at the phagosome through an interaction with Rab20
    Tomohiro Segawa
    Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734 8553, Japan
    Biochem J 464:365-75. 2014
    ..The expression of a constitutively active form of Rab5b in the shInpp5e cells rescued the PtdIns3P accumulation. Rab20 has been reported to regulate the activity of Rabex5, a guanine nucleotide exchange factor for Rab5...
  3. pmc Rab20 regulates phagosome maturation in RAW264 macrophages during Fc gamma receptor-mediated phagocytosis
    Youhei Egami
    Department of Histology and Cell Biology, School of Medicine, Kagawa University, Miki, Kagawa, Japan
    PLoS ONE 7:e35663. 2012
    b>Rab20, a member of the Rab GTPase family, is known to be involved in membrane trafficking, however its implication in FcγR-mediated phagocytosis is unclear...
  4. doi Expression profiling of Rab GTPases reveals the involvement of Rab20 and Rab32 in acute brain inflammation in mice
    Yajie Liang
    Department of Neurobiology, Third Military Medical University, Chongqing 400038, PR China
    Neurosci Lett 527:110-4. 2012
    ..We found that Rab20 and Rab32 were substantially up-regulated during the acute phase of inflammation...
  5. ncbi The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach
    P Chavrier
    Cell Biology Programme, European Molecular Biology Laboratory, Heidelberg, F R G
    Gene 112:261-4. 1992
    ..These results confirm that the overall diversity of the Rab and Rho protein subfamilies account for more than thirty different members in mammalian cells...
  6. ncbi Expression of Rab proteins during mouse embryonic development
    C Murphy
    Cell Biology Program, European Molecular Biology Laboratory, Heidelberg, Germany
    Methods Enzymol 257:324-32. 1995
  7. ncbi Genetic mapping of Rab20 on mouse chromosome 8
    E B McMurtrie
    Department of Medicine, University of Florida, Gainesville, Florida 32610 0221, USA
    Mamm Genome 8:291-2. 1997
  8. ncbi A locus for renal malformations including vesico-ureteric reflux on chromosome 13q33-34
    Kalyani R Vats
    Department of Pediatrics, Division of Pediatric Nephrology, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Am Soc Nephrol 17:1158-67. 2006
    ..Herein is reported a new locus on chromosome 13q33q34 that can be associated with VUR with several genes showing mRNA expression patterns that suggest their potential for involvement in renal/urinary tract developmental anomalies...
  9. doi The GTPase RAB20 is a HIF target with mitochondrial localization mediating apoptosis in hypoxia
    Thomas Hackenbeck
    University of Erlangen Nuremberg, Erlangen, Germany
    Biochim Biophys Acta 1813:1-13. 2011
    ..Here, we describe the characterization of a new HIF-1 target gene, Rab20, which is a member of the Rab family of small GTP-binding proteins, regulating intracellular trafficking and ..