Pgc

Summary

Gene Symbol: Pgc
Description: progastricsin (pepsinogen C)
Alias: 2210410L06Rik, Upg-1, Upg1, gastricsin, pepsinogen C, urinary pepsinogen 1
Species: mouse

Top Publications

  1. pmc Cdx2 determines the fate of postnatal intestinal endoderm
    Emma J Stringer
    Department of Biochemistry, Henry Wellcome Building, University of Leicester, Lancaster Road, Leicester LE1 7RH, UK
    Development 139:465-74. 2012
  2. ncbi Linkage of a gene controlling urinary pepsinogen with the major histocompatibility complex of the mouse
    J M Szymura
    Immunogenetics 13:267-71. 1981
  3. ncbi Genetic variation of urinary pepsinogen and its probable linkage to albinism in the rat
    D V Cramer
    Immunogenetics 13:555-8. 1981
  4. ncbi Localization of new genes and markers to the distal part of the human major histocompatibility complex (MHC) region and comparison with the mouse: new insights into the evolution of mammalian genomes
    C Amadou
    CNRS UPR 8291, CHU de Purpan, Toulouse, France
    Genomics 26:9-20. 1995
  5. ncbi The alpha 2(XI) collagen gene lies within 8 kb of Pb in the proximal portion of the murine major histocompatibility complex
    L Stubbs
    Biology Division, Oak Ridge National Laboratory, Tennessee 37831 8077
    Mamm Genome 4:95-103. 1993
  6. ncbi Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling
    Bradley Spencer-Dene
    Experimental Pathology Laboratory, Cancer Research UK, London Research Institute, London, England
    Gastroenterology 130:1233-44. 2006
  7. pmc Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification
    Ioannis M Stylianou
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Genetics 178:1795-805. 2008
  8. pmc Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells
    Michael P Verzi
    Dana Farber Cancer Institute and Department of Medicine, Boston, Massachusetts, USA
    Gastroenterology 135:591-600. 2008
  9. pmc Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice
    Shinichi Nakagawa
    RNA Biology Laboratory, RIKEN Advanced Science Institute, 2 1 Hirosawa, Saitama 351 0198, Japan
    J Cell Biol 193:31-9. 2011
  10. ncbi Upg-2: a urinary pepsinogen variant located on chromosome 1 of the mouse
    J M Szymura
    Biochem Genet 20:1211-9. 1982

Scientific Experts

  • Shinichi Nakagawa
  • Bradley Spencer-Dene
  • Emma J Stringer
  • Michael P Verzi
  • Ioannis M Stylianou
  • Jacqueline Deschamps
  • Doug J Winton
  • Irwin Davidson
  • Toshiro Sato
  • Nicholas A Wright
  • Nick Barker
  • Catrin A Pritchard
  • Hans Clevers
  • Isabelle Duluc
  • Monika Bialecka
  • Felix Beck
  • Thoueiba Saandi
  • Jean Noel Freund
  • Fadi A Abdi
  • Gary A Churchill
  • Sanjeev Bhardwaj
  • Susumu Ito
  • Beverly Paigen
  • Robert Y Wilpan
  • Jason P Affourtit
  • Keith R Shockley
  • Ramesh A Shivdasani
  • Abdul H Khan
  • Jarod Rollins
  • C Amadou
  • J Klein
  • J M Szymura
  • L Stubbs
  • P Avoustin
  • P Pontarotti
  • N G Copeland
  • N A Jenkins
  • M T Ribouchon
  • M G Mattei
  • D J Gilbert
  • V Vincek
  • L J Ng
  • D Klein
  • V C Lui
  • K S Cheah
  • F Figueroa
  • S Richards
  • J Sertic
  • D V Cramer
  • J H Nadeau
  • P D'Eustachio
  • L C Skow
  • M Bucan
  • P B Samollow
  • B A Taylor
  • B Herrmann
  • K Brorson
  • M A Erhart
  • A Schnattinger
  • K F Lindahl
  • A L Ford
  • B Fein
  • J P Kraus
  • F Michiels
  • H Lehrach
  • S W Hunt
  • J L Vandeberg
  • M Kasahara
  • H Kawaguchi
  • J Forejt
  • M Kosowsky
  • M E Donner
  • J Michaelson
  • F D Ledley
  • C S David
  • Z Zaleska-Rutczynska
  • K Mizuno
  • J L Crosby
  • D Burkart
  • M C Kiefer
  • T C Douglas

Detail Information

Publications20

  1. pmc Cdx2 determines the fate of postnatal intestinal endoderm
    Emma J Stringer
    Department of Biochemistry, Henry Wellcome Building, University of Leicester, Lancaster Road, Leicester LE1 7RH, UK
    Development 139:465-74. 2012
    ....
  2. ncbi Linkage of a gene controlling urinary pepsinogen with the major histocompatibility complex of the mouse
    J M Szymura
    Immunogenetics 13:267-71. 1981
  3. ncbi Genetic variation of urinary pepsinogen and its probable linkage to albinism in the rat
    D V Cramer
    Immunogenetics 13:555-8. 1981
  4. ncbi Localization of new genes and markers to the distal part of the human major histocompatibility complex (MHC) region and comparison with the mouse: new insights into the evolution of mammalian genomes
    C Amadou
    CNRS UPR 8291, CHU de Purpan, Toulouse, France
    Genomics 26:9-20. 1995
    ..Finally, we show that the region found around the breakpoint was involved several times in chromosome recombinations in the mouse lineage, as it seems to correspond also to the t-complex distal inversion point...
  5. ncbi The alpha 2(XI) collagen gene lies within 8 kb of Pb in the proximal portion of the murine major histocompatibility complex
    L Stubbs
    Biology Division, Oak Ridge National Laboratory, Tennessee 37831 8077
    Mamm Genome 4:95-103. 1993
    ..The conserved location of these genes raises the possibility that type XI collagen genes may contribute to one or more of the diverse hereditary disorders known to be linked to the MHC in mouse and human...
  6. ncbi Stomach development is dependent on fibroblast growth factor 10/fibroblast growth factor receptor 2b-mediated signaling
    Bradley Spencer-Dene
    Experimental Pathology Laboratory, Cancer Research UK, London Research Institute, London, England
    Gastroenterology 130:1233-44. 2006
    ..Mice lacking either component (Fgfr2b-/- or Fgf10-/-) were examined to determine the role of Fgfr2b-mediated signaling during gastric organogenesis...
  7. pmc Applying gene expression, proteomics and single-nucleotide polymorphism analysis for complex trait gene identification
    Ioannis M Stylianou
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Genetics 178:1795-805. 2008
    ..We conclude that all three approaches are important and that focusing on a single approach such as mRNA expression may fail to identify a QTL gene...
  8. pmc Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells
    Michael P Verzi
    Dana Farber Cancer Institute and Department of Medicine, Boston, Massachusetts, USA
    Gastroenterology 135:591-600. 2008
    ..We identified stomach-restricted expression of the forkhead transcription factor FOXQ1...
  9. pmc Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice
    Shinichi Nakagawa
    RNA Biology Laboratory, RIKEN Advanced Science Institute, 2 1 Hirosawa, Saitama 351 0198, Japan
    J Cell Biol 193:31-9. 2011
    ..We propose that paraspeckles are nonessential, subpopulation-specific nuclear bodies formed secondary to particular environmental triggers...
  10. ncbi Upg-2: a urinary pepsinogen variant located on chromosome 1 of the mouse
    J M Szymura
    Biochem Genet 20:1211-9. 1982
    ..Typing of recombinant inbred strains suggests that the location of the Upg-2 locus is on chromosome 1, in the vicinity of loci coding for other peptidases, namely, Pep-2 and Rnr, and of the Acf-1 locus...
  11. ncbi Polymorphism of the Apl (Neu-1) locus in the mouse
    D Klein
    Immunogenetics 16:181-4. 1982
  12. ncbi Mapping of the L-methylmalonyl-CoA mutase gene to mouse chromosome 17
    J Sertic
    Max Planck Institut fur Biologie, Abteilung Immungenetik, Tubingen, Federal Republic of Germany
    Genomics 6:560-4. 1990
    ..06 cM distal to H-2, between Pgk-2 and Ce-2. The relative order of syntenic probes flanking H-2 on mouse chromosome 17 and HLA on human chromosome 6 is shown to be different...
  13. pmc Genetic and molecular mapping of the Hmt region of mouse
    S Richards
    Howard Hughes Medical Institute, Dallas, TX
    EMBO J 8:3749-57. 1989
    ..4. Both lie proximal to Pgk-2, within the distal inversion in t-haplotypes. The presence of several other MHC class I genes in the Hmt region is predicted from analysis of the recombinants that define the region...
  14. pmc The locus encoding alpha A-crystallin is closely linked to H-2K on mouse chromosome 17
    L C Skow
    Genetics 110:723-32. 1985
    ..Analysis of congenic and recombinant congenic strains of mice confirmed the linkage of Acry-1 and H-2 and located the alpha A gene to the region between glyoxylase (Glo-1) and H-2K...
  15. ncbi Electrophoretic analysis of liver neuraminidase-1 variation in mice and additional evidence concerning the location of NEU-1
    P B Samollow
    J Immunogenet 13:29-39. 1986
    ..Recombination rates among six H-2-linked marker loci were unexpectedly low, but were sufficient to verify the position of Upg-1 as the telomeric flanking marker relative to Glo-1, H-2 (C4), Neu-1 (Apl), Ce-2 and Pgk-2...
  16. pmc The alpha-globin pseudogene on mouse chromosome 17 is closely linked to H-2
    P D'Eustachio
    J Exp Med 159:958-63. 1984
    ..Hba-a4 is the first mammalian dispersed pseudogene to be localized in a linkage map, and should provide a useful marker for the region of chromosome 17 proximal to H-2...
  17. ncbi Mapping of the mouse Upg-1 locus
    J M Szymura
    Immunogenetics 16:89-90. 1982
  18. ncbi Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci
    J H Nadeau
    Jackson Laboratory, Bar Harbor, Maine 04609
    Genomics 9:78-89. 1991
    ....
  19. ncbi Linkage map of mouse chromosome 17: localization of 27 new DNA markers
    V Vincek
    Max Planck Institut fur Biologie, Abteilung Immungenetik, Tubingen, Federal Republic of Germany
    Genomics 5:773-86. 1989
    ..The distal region of MMU17, on the other hand, is populated by only a few, rather imprecisely mapped markers. Molecular maps are available for most of the H-2 complex and for parts of the t complex...
  20. ncbi H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17
    J Klein
    Immunogenetics 16:285-317. 1982