PARP 3

Summary

Gene Symbol: PARP 3
Description: poly (ADP-ribose) polymerase family, member 3
Alias: A930002C11Rik, AW990611, Adprt3, Adprtl3, PARP-3, pADPRT-3, poly [ADP-ribose] polymerase 3, A DP-ribosyltransferase (NAD+; poly (ADP-ribose polymerase)-like 3, ADP-ribosyltransferase (NAD+, poly (ADP-ribose polymerase)-like 3, NAD+ ADP-ribosyltransferase 3, Poly[ADP-ribose] synthetase-3
Species: mouse

Top Publications

  1. pmc Parp3 negatively regulates immunoglobulin class switch recombination
    Isabelle Robert
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France Centre National de Recherche Scientifique, UMR7104, Illkirch, France Université de Strasbourg, Illkirch, France
    PLoS Genet 11:e1005240. 2015
  2. ncbi Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9
    P Urbanek
    Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague
    Folia Biol (Praha) 48:182-91. 2002
  3. doi PARP-3 and APLF function together to accelerate nonhomologous end-joining
    Stuart L Rulten
    Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton BN1 9RQ, UK
    Mol Cell 41:33-45. 2011
  4. pmc Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
    Christian Boehler
    Research Institute of the Biotechnology School of Strasbourg, UMR7242, Ecole Superieure de Biotechnologie de Strasbourg, 67412 Illkirch, France
    Proc Natl Acad Sci U S A 108:2783-8. 2011

Scientific Experts

  • P Urbanek
  • Isabelle Robert
  • Bernardo Reina-San-Martin
  • Francoise Dantzer
  • Stuart L Rulten
  • Christian Boehler
  • Aurélia Noll
  • Mélanie Rogier
  • Vincent Heyer
  • Léa Gaudot
  • Oliver Mortusewicz
  • Keith W Caldecott
  • Valerie Schreiber
  • Susan Smith
  • Denis S Biard
  • Maria C Zuma
  • Anna E O Fisher
  • Laurent R Gauthier
  • Sarah Sanglier-Cianferani
  • Michele Rouleau
  • Anne Bresson
  • Limei Ju
  • François Boussin
  • Guy Poirier
  • Jean Michel Saliou

Detail Information

Publications4

  1. pmc Parp3 negatively regulates immunoglobulin class switch recombination
    Isabelle Robert
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France Centre National de Recherche Scientifique, UMR7104, Illkirch, France Université de Strasbourg, Illkirch, France
    PLoS Genet 11:e1005240. 2015
    ..We propose that Parp3 plays a CSR-specific role by controlling AID levels at switch regions during CSR. ..
  2. ncbi Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9
    P Urbanek
    Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague
    Folia Biol (Praha) 48:182-91. 2002
    ..We cloned and sequenced the cDNAs of the mouse PARP-3 (Adprt3) gene encoding poly(ADP-ribose) polymerase 3 and of the closely linked U3-55k gene coding for the U3 small ..
  3. doi PARP-3 and APLF function together to accelerate nonhomologous end-joining
    Stuart L Rulten
    Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton BN1 9RQ, UK
    Mol Cell 41:33-45. 2011
    ..These data identify molecular roles for PARP-3 and APLF in chromosomal DNA double-strand break repair reactions...
  4. pmc Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression
    Christian Boehler
    Research Institute of the Biotechnology School of Strasbourg, UMR7242, Ecole Superieure de Biotechnologie de Strasbourg, 67412 Illkirch, France
    Proc Natl Acad Sci U S A 108:2783-8. 2011
    ..Both functions open stimulating prospects for specifically targeting PARP3 in cancer therapy...