Nfix

Summary

Gene Symbol: Nfix
Description: nuclear factor I/X
Alias: CTF, NF-I/X, NF1-X, NFI-X, nuclear factor 1 X-type, CCAAT-box-binding transcription factor, TGGCA-binding protein, nuclear factor 1/X
Species: mouse

Top Publications

  1. pmc Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum
    Michael Piper
    School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
    J Comp Neurol 519:3532-48. 2011
  2. doi Absence of the transcription factor Nfib delays the formation of the basilar pontine and other mossy fiber nuclei
    Asli Kumbasar
    Department of Anatomy and Neurobiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Comp Neurol 513:98-112. 2009
  3. pmc The transcription factor Nfix is essential for normal brain development
    Christine E Campbell
    Dept of Biochemistry and New York State Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, 3435 Main St, Buffalo, NY 14214, USA
    BMC Dev Biol 8:52. 2008
  4. ncbi Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development
    A Z Chaudhry
    Department of Cancer Biology, Research Institute, Cleveland Clinic Foundation, Ohio 44195, USA
    Dev Dyn 208:313-25. 1997
  5. ncbi Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals
    C F Fletcher
    Mammalian Genetics Laboratory, ABL Basic Research Program, NCI Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA
    Mamm Genome 10:390-6. 1999
  6. ncbi Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules
    Wei Wang
    Department of Cellular and Molecular Physiology and Program in Neuroscience, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 27:6115-27. 2007
  7. pmc Nuclear factor I X deficiency causes brain malformation and severe skeletal defects
    Katrin Driller
    Institut fur Biologie III, Fakultat fur Biologie, Albert Ludwigs Universitat Freiburg, Schanzlestrasse 1, D 79104 Freiburg, Germany
    Mol Cell Biol 27:3855-3867. 2007
  8. ncbi Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One
    Albert Gründer
    Institut für Biologie III Genetik, Albert Ludwigs Universitat, Schaenzlestrasse 1, D 79104, Freiburg, Germany
    Gene 304:171-81. 2003
  9. pmc Transcriptional regulation of intermediate progenitor cell generation during hippocampal development
    Lachlan Harris
    The School of Biomedical Sciences, The University of Queensland, Brisbane 4072, Australia
    Development 143:4620-4630. 2016
  10. pmc NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis
    Yee Hsieh Evelyn Heng
    The School of Biomedical Sciences
    Cereb Cortex 24:261-79. 2014

Scientific Experts

  • Michael Piper
  • Yan Zhu
  • Christine E Campbell
  • Umashankar Singh
  • Richard M Gronostajski
  • Lachlan Harris
  • Yee Hsieh Evelyn Heng
  • Linda J Richards
  • Tracey J Harvey
  • Bo Zhou
  • Timothy L Bailey
  • Ben Martynoga
  • Chantelle Dixon
  • Graziella Messina
  • Wei Wang
  • Diana Vidovic
  • Francois Guillemot
  • Kathleen Cato
  • Aaron G Smith
  • Stefania Monteverde
  • Giulio Cossu
  • Giuliana Rossi
  • Shahragim Tajbakhsh
  • Caitriona O'Connor
  • Jérome Chal
  • Jason M Osinski
  • Jimena Andersen
  • Angeliki Achimastou
  • Juan L Mateo
  • Per Holmfeldt
  • Anna Pistocchi
  • Jordan T Gladman
  • Christopher M Chamberlain
  • Albert Gründer
  • Celine Plachez
  • Paul P Y Lu
  • R M Gronostajski
  • Marjan Nassiri
  • A Z Chaudhry
  • Amanda K Riffel
  • Zhengquan Yu
  • Asli Kumbasar
  • Daniel L Kilpatrick
  • E David Litwack
  • Hye Yeong Ha
  • Daan Noordermeer
  • Vladimir Pekarik
  • Lili C Kudo
  • Katrin Driller
  • Albrecht E Sippel
  • C F Fletcher
  • Siming Shou
  • JINING LU
  • Jason Osinki
  • Thomas H Burne
  • Ilan Gobius
  • Stefania Antonini
  • Chiara Bonfanti
  • Oressia Zalucki
  • Alexandra Essebier
  • Li Pan
  • Julian I Heng
  • Ivan Gladwyn-Ng
  • Chiara Vezzali
  • Hannah McDonald
  • Leif Kennedy
  • Getzabel Guevara
  • Jean Marie Garnier
  • Frederic Relaix
  • Ayako Miyanari
  • Olga Sumara
  • Jason Osinski
  • Olivier Tassy
  • Masayuki Oginuma
  • Alison M Michie
  • Marie Hestin
  • Joana Campos
  • Thomas Cherrier
  • Karen Keeshan
  • Shinichiro Hayashi
  • Bénédicte Gobert
  • Aurore Hick
  • Ziad Al Tanoury
  • Tracey Harvey
  • Aaron Smith
  • Bernadette Drayton
  • Yasmine Zidouni
  • Elise Horne
  • Emanuela Gussoni
  • Olivier Pourquie

Detail Information

Publications46

  1. pmc Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum
    Michael Piper
    School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
    J Comp Neurol 519:3532-48. 2011
    ..Here, we address the role of the transcription factor nuclear factor one X (NFIX), in postnatal development of the cerebellum...
  2. doi Absence of the transcription factor Nfib delays the formation of the basilar pontine and other mossy fiber nuclei
    Asli Kumbasar
    Department of Anatomy and Neurobiology and Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Comp Neurol 513:98-112. 2009
    ..While the mossy fiber nuclei of the caudal medulla do form, they also exhibit a developmental delay. Nfia and Nfix null mice exhibit no apparent pontine phenotype, implying specificity in the action of NFI family members...
  3. pmc The transcription factor Nfix is essential for normal brain development
    Christine E Campbell
    Dept of Biochemistry and New York State Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, 3435 Main St, Buffalo, NY 14214, USA
    BMC Dev Biol 8:52. 2008
    ..Recently the Nfix gene has been disrupted and these studies indicated that there were largely uncharacterized defects in brain and ..
  4. ncbi Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development
    A Z Chaudhry
    Department of Cancer Biology, Research Institute, Cleveland Clinic Foundation, Ohio 44195, USA
    Dev Dyn 208:313-25. 1997
    ..We have isolated cDNAs from all four murine NFI genes (gene designations Nfia, Nfib, Nfic, and Nfix), assessed the embryonic and postnatal expression patterns of the NFI genes, and determined the ability of specific ..
  5. ncbi Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals
    C F Fletcher
    Mammalian Genetics Laboratory, ABL Basic Research Program, NCI Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA
    Mamm Genome 10:390-6. 1999
    ..elegans NFI genes. The four murine NFI genes are on Chrs 4 (Nfia and Nfib), 8 (Nfix), and 10 (Nfic), suggesting early duplication of the genes and dispersal throughout the genome...
  6. ncbi Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules
    Wei Wang
    Department of Cellular and Molecular Physiology and Program in Neuroscience, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 27:6115-27. 2007
    ..Furthermore, they reveal how a single transcription factor family can control and integrate multiple aspects of neuronal differentiation through the regulation of cell adhesion molecules...
  7. pmc Nuclear factor I X deficiency causes brain malformation and severe skeletal defects
    Katrin Driller
    Institut fur Biologie III, Fakultat fur Biologie, Albert Ludwigs Universitat Freiburg, Schanzlestrasse 1, D 79104 Freiburg, Germany
    Mol Cell Biol 27:3855-3867. 2007
    ..factor family of nuclear factor I (NFI) proteins is encoded by four closely related genes: Nfia, Nfib, Nfic, and Nfix. A potential role for NFI proteins in regulating developmental processes has been implicated by their specific ..
  8. ncbi Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One
    Albert Gründer
    Institut für Biologie III Genetik, Albert Ludwigs Universitat, Schaenzlestrasse 1, D 79104, Freiburg, Germany
    Gene 304:171-81. 2003
    ....
  9. pmc Transcriptional regulation of intermediate progenitor cell generation during hippocampal development
    Lachlan Harris
    The School of Biomedical Sciences, The University of Queensland, Brisbane 4072, Australia
    Development 143:4620-4630. 2016
    ..Here, we examined IPC production using mice lacking the transcription factor nuclear factor I/X (Nfix)...
  10. pmc NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis
    Yee Hsieh Evelyn Heng
    The School of Biomedical Sciences
    Cereb Cortex 24:261-79. 2014
    ..Here, we demonstrate that Nuclear factor one X (NFIX) is expressed by neural progenitor cells within the embryonic hippocampus, and that progenitor cell differentiation ..
  11. pmc Heterozygosity for nuclear factor one x affects hippocampal-dependent behaviour in mice
    Lachlan Harris
    The School of Biomedical Sciences, The University of Queensland, Brisbane, Australia
    PLoS ONE 8:e65478. 2013
    ..the Nuclear factor one (Nfi) family, which encodes four site-specific transcription factors, NFIA, NFIB, NFIC and NFIX. In mice lacking Nfia, Nfib or Nfix, aspects of early hippocampal development, including neurogenesis within the ..
  12. doi Nuclear factor one X regulates Bobby sox during development of the mouse forebrain
    Chantelle Dixon
    The School of Biomedical Sciences, The University of Queensland, Brisbane, QLD, 4072, Australia
    Cell Mol Neurobiol 33:867-73. 2013
    The transcription factor nuclear factor one X (NFIX) plays a central role during the development of the neocortex and hippocampus, through the activation of astrocyte-specific gene expression and the repression of progenitor-specific ..
  13. pmc Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence
    Ben Martynoga
    Division of Molecular Neurobiology, MRC National Institute for Medical Research, London NW7 1AA, United Kingdom
    Genes Dev 27:1769-86. 2013
    ..Interestingly, we found that the family member NFIX is robustly induced when NS cells enter quiescence...
  14. pmc Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1)
    Jordan T Gladman
    Department of Pathology, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS ONE 8:e72907. 2013
    ..Furthermore, these results also represent the first murine model for early-onset DM1 and provide a tool to investigate the effects of RNA toxicity at various stages of development. ..
  15. pmc Nfix is a novel regulator of murine hematopoietic stem and progenitor cell survival
    Per Holmfeldt
    Department of Hematology and
    Blood 122:2987-96. 2013
    ..Here we show that Nfix, a member of the nuclear factor I (Nfi) family of transcription factors, is highly expressed by hematopoietic stem ..
  16. pmc NFIX Regulates Proliferation and Migration Within the Murine SVZ Neurogenic Niche
    Yee Hsieh Evelyn Heng
    The School of Biomedical Sciences
    Cereb Cortex 25:3758-78. 2015
    ..One member, NFIX, regulates the development of the neocortex, hippocampus, and cerebellum...
  17. pmc Nfix expression critically modulates early B lymphopoiesis and myelopoiesis
    Caitriona O'Connor
    Paul O Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, Scotland
    PLoS ONE 10:e0120102. 2015
    ..factors are important in regulating hematopoiesis and here we report an important physiological role of NFIX in B- and myeloid lineage commitment and differentiation...
  18. doi Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX
    Diana Vidovic
    The School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia
    Brain Res 1616:71-87. 2015
    Nuclear factor one X (NFIX) has been shown to play a pivotal role during the development of many regions of the brain, including the neocortex, the hippocampus and the cerebellum...
  19. ncbi Nuclear factor I (NFI) isoforms differentially activate simple versus complex NFI-responsive promoters
    A Z Chaudhry
    Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Biol Chem 273:18538-46. 1998
    ..Here, we show that NFI heterodimers have intermediate activation potentials compared with homodimers, demonstrating one potential mechanism by which different NFI proteins can regulate gene expression...
  20. doi Loss of NFIX Transcription Factor Biases Postnatal Neural Stem/Progenitor Cells Toward Oligodendrogenesis
    Bo Zhou
    1 Department of Biochemistry, Genomics and Bioinformatics Program, New York State Center of Excellence in Bioinformatics and Life Sciences, State University of New York at Buffalo, Buffalo, New York
    Stem Cells Dev 24:2114-26. 2015
    ..In this study, we show that nuclear factor I X (NFIX), a transcription factor known to regulate NSC quiescence, also suppresses oligodendrogenesis (ODG) from NSCs...
  21. doi Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy
    Jérome Chal
    Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, CNRS UMR 7104, INSERM U964, Universite de Strasbourg, Illkirch Graffenstaden, France
    Nat Biotechnol 33:962-9. 2015
    ..Fibers derived from ES cells of mdx mice exhibit an abnormal branched phenotype resembling that described in vivo, thus providing an attractive model to study the origin of the pathological defects associated with DMD. ..
  22. pmc Nfix Regulates Temporal Progression of Muscle Regeneration through Modulation of Myostatin Expression
    Giuliana Rossi
    Department of Biosciences, University of Milan, Via Celoria 26, 20133 Milan, Italy
    Cell Rep 14:2238-49. 2016
    b>Nfix belongs to a family of four highly conserved proteins that act as transcriptional activators and/or repressors of cellular and viral genes...
  23. doi Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution
    Anna Pistocchi
    Department of Biosciences, University of Milan, Via Celoria 26, 20133 Milan, Italy
    Development 140:1528-36. 2013
    During mouse skeletal muscle development, the Nfix gene has a pivotal role in regulating fetal-specific transcription. Zebrafish and mice share related programs for muscle development, although zebrafish develops at a much faster rate...
  24. pmc Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise
    Christopher M Chamberlain
    Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN, USA
    Hum Mol Genet 21:4645-54. 2012
    ..In summary, MBNL1 overexpression may be a valuable strategy for treating the skeletal muscle features of DM...
  25. doi Serum response factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination
    Paul P Y Lu
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 31:16651-64. 2011
    ....
  26. pmc Temporal control of a dendritogenesis-linked gene via REST-dependent regulation of nuclear factor I occupancy
    Wei Wang
    Department of Microbiology and Physiological Systems and Program in Neuroscience, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Mol Biol Cell 22:868-79. 2011
    ..They also establish a temporal function for REST in preventing premature promoter occupancy by NFI proteins in early-stage postmitotic neurons...
  27. doi SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation
    Yan Zhu
    Graduate School of Frontier Biosciences, Osaka University, Yamadaoka 1 3, Suita, Osaka 565 0871, Japan
    Development 136:1919-28. 2009
    ..Furthermore, we provide the first in vivo evidence that pontine neurons themselves induce collateral branching from the corticospinal axons...
  28. ncbi Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain
    Lili C Kudo
    Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
    Cereb Cortex 17:2108-22. 2007
    ..These data provide an important set of new candidates for studies of cortical patterning and maturation...
  29. ncbi Mapping of the murine nuclear factor I/X gene (Nfix) to mouse chromosome 8 C1-2 by FISH
    H Scherthan
    Abt Humanbiologie und Humangenetik der Universität, Kaiserslautern, Germany
    Genomics 22:247-9. 1994
  30. ncbi NFI/X proteins: a class of NFI family of transcription factors with positive and negative regulatory domains
    G Nebl
    Forschungszentrum Karlsruhe, Institute of Genetics, Germany
    Cell Mol Biol Res 41:85-95. 1995
    ..With the identification of the negative domain in the NFI/X proteins, we demonstrate here a novel regulatory feature of these proteins in positive and negative modulation of gene expression...
  31. ncbi Absence epilepsy in tottering mutant mice is associated with calcium channel defects
    C F Fletcher
    Mammalian Genetics Laboratory, NCI Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA
    Cell 87:607-17. 1996
    ..These studies define the first mutations in a mammalian central nervous system-specific voltage-sensitive calcium channel and identify the first gene involved in absence epilepsy...
  32. ncbi Altered expression of the developmentally regulated NFI gene family during phorbol ester-induced differentiation of human leukemic cells
    S Kulkarni
    Department of Cancer Biology, Cleveland Clinic Foundation, Ohio 44195, USA
    Cell Growth Differ 7:501-10. 1996
    ..These studies indicate that although their DNA-binding specificities are similar, the proteins encoded by the four NFI genes may differ in their biological functions and play distinct roles in hematopoietic development...
  33. ncbi NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression
    M Behrens
    Department of Anatomy and Neurobiology, University of Maryland at Baltimore, School of Medicine, Baltimore, MD 21201, USA
    Eur J Neurosci 12:1372-84. 2000
    ..These data on NFI activity, and on transcription factor expression, provide a basis to understand the role of NFI in regulating gene expression in olfactory receptor neurons...
  34. ncbi Transcription factor NF 1 expression in involuting mammary gland
    R Kane
    Dept of Pharmacology, University College Dublin, Belfield, Ireland
    Adv Exp Med Biol 480:117-22. 2000
    Transcripts of each of the four NF1 genes (NF1 A, B, C (CTF/NF1) and X) are expressed in both lactating and involuting mouse mammary gland but there is an indication that increased expression of an NF1 C (CTF/NF1) transcript accompanies ..
  35. ncbi Regulation of renin enhancer activity by nuclear factor I and Sp1/Sp3
    Li Pan
    Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263 0001, USA
    Biochim Biophys Acta 1625:280-90. 2003
    ..Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assays have demonstrated that NFI-X is the predominant NFI mRNA expressed in As4.1 cells. Direct study of involvement of NFI-X in regulation of renin genes is underway...
  36. ncbi Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung
    JINING LU
    Pulmonary Center, Boston University School of Medicine, Boston, MA 02118, USA
    Dev Biol 273:418-35. 2004
    ..Our data suggest that these genes may regulate focal developmental events specific of each of these regions during respiratory tract formation...
  37. ncbi Transcriptome analysis of the murine forelimb and hindlimb autopod
    Siming Shou
    Research Division, Shriners Hospital for Children, Portland, OR 97239, USA
    Dev Dyn 234:74-89. 2005
    ..05) suggesting that by E 12.5, unique gene combinations are being used during the differentiation of each autopod type...
  38. pmc Repressors NFI and NFY participate in organ-specific regulation of von Willebrand factor promoter activity in transgenic mice
    Marjan Nassiri
    Department of Medicine, University of Alberta, Edmonton, AL, Canada
    Arterioscler Thromb Vasc Biol 30:1423-9. 2010
    ..To determine the role of repressors in cell type and organ-specific activation of von Willebrand factor (VWF) promoter sequences -487 to 247 in vivo...
  39. doi Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins
    Hye Yeong Ha
    Division of Nano Sciences and Brain Disease Research Institute, Ewha Womans University, Seoul, Republic of Korea
    Proteomics 8:1071-80. 2008
    ....
  40. pmc Transcription and chromatin organization of a housekeeping gene cluster containing an integrated beta-globin locus control region
    Daan Noordermeer
    Department of Cell Biology and Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
    PLoS Genet 4:e1000016. 2008
    ..We identified long-range interactions between the LCR and two upregulated genes and propose that LCR-gene contacts via chromatin looping determine which genes are transcriptionally enhanced...
  41. pmc NFIX--one gene, two knockouts, multiple effects
    Vladimir Pekarik
    Center of Regenerative Medicine in Barcelona, Doctor Aiguader 88, 08003 Barcelona, Spain
    J Biol 7:29. 2008
    A previous knockout of the transcription factor gene nuclear factor IX (NFIX) in mice produced impaired development of the corpus callosum and severe skeletal defects...
  42. pmc A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions
    Umashankar Singh
    Department of Genetics and Pathology, Uppsala University, Uppsala, Sweden
    PLoS ONE 4:e5050. 2009
    Though the Nuclear factor 1 family member NFIX has been strongly implicated in PDGFB-induced glioblastoma, its molecular mechanisms of action remain unknown...
  43. ncbi Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH
    F Qian
    Institut fur Biologie III, Universitat Freiburg, Germany
    Genomics 28:66-73. 1995
    ..in the human genome, we isolated partial cDNA sequences derived from four independent genes: NFIA, NFIB, NFIC, and NFIX. Corresponding clones of genomic DNA served as probes for fluorescence in situ hybridization on human metaphase ..
  44. pmc The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation
    Zhengquan Yu
    Department of Medicine, University of California, Irvine, CA 92697 4030, USA
    EMBO J 28:1890-903. 2009
    ..These results show a crucial role for Get1 in urothelial differentiation and barrier formation...
  45. doi Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family
    Amanda K Riffel
    Division of Pediatric Clinical Pharmacology and Medical Toxicology, Department of Pediatrics, Children s Mercy Hospital and Clinics, Kansas City, MO 64108, USA
    Mol Pharmacol 76:1104-14. 2009
    ..These results demonstrate that members of the NFI transcription factor family regulate CYP3A4 and CYP3A7 basal expression in an isoform- and promoter-specific manner...
  46. doi Nfix regulates fetal-specific transcription in developing skeletal muscle
    Graziella Messina
    San Raffaele Scientific Institute, Milan, Italy
    Cell 140:554-66. 2010
    ..We show here that the transcription factor nuclear factor one X (Nfix), whose expression is activated by Pax7 in fetal muscle, in turn activates the transcription of fetal specific ..