Hist1h3f

Summary

Gene Symbol: Hist1h3f
Description: histone cluster 1, H3f
Alias: H3.2-221, Hist1, histone H3.2, histone 1, H3f, histone H3, histone gene complex 1
Species: mouse

Top Publications

  1. ncbi Linkage of loci associated with two pigment mutations on mouse chromosome 13
    R F Holcombe
    Department of Medicine, LSU Medical Center, Shreveport 71130
    Genet Res 58:41-50. 1991
  2. pmc Histone H3.3 maintains genome integrity during mammalian development
    Chuan Wei Jang
    Department of Genetics, Carolina Center for Genome Sciences, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Genes Dev 29:1377-92. 2015
  3. ncbi Activation of the mitogen-activated protein kinase ERK1 during meiotic progression of mouse pachytene spermatocytes
    C Sette
    Dipartimento di Sanita Pubblica e Biologia Cellulare, Sezione di Anatomia, Universita di Roma Tor Vergata, Via O Raimondo 8, 00173, Rome, Italy
    J Biol Chem 274:33571-9. 1999
  4. doi Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression
    Midori Shimada
    Department of Cell Biology and Biochemistry, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
    Cell 132:221-32. 2008
  5. pmc Sequentially acting Sox transcription factors in neural lineage development
    Maria Bergsland
    Ludwig Institute for Cancer Research, Department of Cell and Molecular Biology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Genes Dev 25:2453-64. 2011
  6. pmc Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancer
    Laxmi G Pellakuru
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Pathol 181:560-9. 2012
  7. pmc Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes
    Chih Chi Yuan
    Department of Molecular Biology, Massachusetts General Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA
    Cell Rep 1:83-90. 2012
  8. pmc Hepatic lipid accumulation alters global histone h3 lysine 9 and 4 trimethylation in the peroxisome proliferator-activated receptor alpha network
    Hee Jin Jun
    Department of Biotechnology, Graduate School of Life Sciences and Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea
    PLoS ONE 7:e44345. 2012
  9. pmc The polycomb group protein Bmi1 binds to the herpes simplex virus 1 latent genome and maintains repressive histone marks during latency
    Dacia L Kwiatkowski
    Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, 32610 0266, USA
    J Virol 83:8173-81. 2009
  10. pmc cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progression
    PEDRO RODRIGUEZ-COLLAZO
    Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Exp Cell Res 314:2855-69. 2008

Scientific Experts

  • P Lefebvre
  • Chuan Wei Jang
  • Laxmi G Pellakuru
  • Hee Jin Jun
  • Chih Chi Yuan
  • Maria Bergsland
  • Dacia L Kwiatkowski
  • PEDRO RODRIGUEZ-COLLAZO
  • Midori Shimada
  • Mahalakshmi Nair
  • Masatoshi Ooga
  • Alexandre Blais
  • Z F Wang
  • Shin ichi Horike
  • Michael S Rogers
  • Terry Magnuson
  • Della Yee
  • Joshua Starmer
  • Yoichiro Shibata
  • Lili Wang
  • Bruno Lefebvre
  • W F Marzluff
  • Mark L Borowsky
  • Tsuyoshi Iwata
  • Bora Gurel
  • Adam G W Matthews
  • Chang Feng Chen
  • Toshiro K Ohsumi
  • JinYoung Kim
  • Marjorie A Oettinger
  • Carlise Bethel
  • Kevin Struhl
  • Sung Joon Lee
  • Denise Schultz
  • Angelo M De Marzo
  • Srinivasan Yegnasubramanian
  • Tatiana G Kutateladze
  • Karen C Glass
  • Jessica Hicks
  • Minh Hien Hoang
  • Brad A Chapman
  • Yi Jin
  • Cécile Zaouter
  • Rickard Sandberg
  • Jonas Muhr
  • Susanne Klum
  • Daniel Ramsköld
  • N K Kaludov
  • J W Hudson
  • David C Bloom
  • Hilary W Thompson
  • Tomohiko Akiyama
  • Rebecca C Chiffer
  • Paolo Sassone-Corsi
  • Doaa H Zineldeen
  • Masafumi Tanaka
  • Fugaku Aoki
  • Hideaki Tagami
  • Masao Nagata
  • Hiroyuki Saito
  • Peng Sun
  • Catharine L Smith
  • Sara K Snyder
  • Boan Li
  • Ippei Nagamori
  • Makoto Nakanishi
  • Hiroyuki Niida
  • Erin A Bressler
  • Azusa Inoue
  • Ty C Voss
  • Hans Gottfried Genieser
  • Catherine Rhéaume
  • Eric P Anderson
  • C Sette
  • Shun Ichiro Kageyama
  • Durga Prasad Mishra
  • Xing Dai
  • Diego Acosta-Alvear
  • Raphael Margueron
  • Brian David Dynlacht
  • Chris J C van Oevelen
  • Terumi Kohwi-Shigematsu
  • Masaru Miyano
  • Shutao Cai
  • Jan Fang Cheng
  • Richard M Rohan
  • H J Clarke
  • Amy E Birsner
  • M M Hurt
  • V D Brown

Detail Information

Publications36

  1. ncbi Linkage of loci associated with two pigment mutations on mouse chromosome 13
    R F Holcombe
    Department of Medicine, LSU Medical Center, Shreveport 71130
    Genet Res 58:41-50. 1991
    ..and pe loci and the loci for the T-cell receptor gamma-chain gene (Tcrg), the spermatocyte specific histone gene (Hist1), the prolactin gene (Prl), the Friend murine leukaemia virus integration site 1 (Fim-1), the murine Hanukuh ..
  2. pmc Histone H3.3 maintains genome integrity during mammalian development
    Chuan Wei Jang
    Department of Genetics, Carolina Center for Genome Sciences, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Genes Dev 29:1377-92. 2015
    b>Histone H3.3 is a highly conserved histone H3 replacement variant in metazoans and has been implicated in many important biological processes, including cell differentiation and reprogramming. Germline and somatic mutations in H3...
  3. ncbi Activation of the mitogen-activated protein kinase ERK1 during meiotic progression of mouse pachytene spermatocytes
    C Sette
    Dipartimento di Sanita Pubblica e Biologia Cellulare, Sezione di Anatomia, Universita di Roma Tor Vergata, Via O Raimondo 8, 00173, Rome, Italy
    J Biol Chem 274:33571-9. 1999
    ....
  4. doi Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression
    Midori Shimada
    Department of Cell Biology and Biochemistry, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
    Cell 132:221-32. 2008
    ..We show here that DNA damage rapidly reduces histone H3 Threonine 11 (T11) phosphorylation. This correlates with repression of genes, including cyclin B1 and cdk1...
  5. pmc Sequentially acting Sox transcription factors in neural lineage development
    Maria Bergsland
    Ludwig Institute for Cancer Research, Department of Cell and Molecular Biology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Genes Dev 25:2453-64. 2011
    ..These data indicate that a single key transcription factor family acts sequentially to coordinate neural gene expression from the early lineage specification in pluripotent cells to later stages of neuronal development...
  6. pmc Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancer
    Laxmi G Pellakuru
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Am J Pathol 181:560-9. 2012
    ..These findings suggest that increased levels of decondensed chromatin in both normal progenitor cells and cancer cells are associated with global loss of H3K27me3, which is linked to MYC overexpression...
  7. pmc Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes
    Chih Chi Yuan
    Department of Molecular Biology, Massachusetts General Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA
    Cell Rep 1:83-90. 2012
    The preferential in vitro interaction of the PHD finger of RAG2, a subunit of the V(D)J recombinase, with histone H3 tails simultaneously trimethylated at lysine 4 and symmetrically dimethylated at arginine 2 (H3R2me2sK4me3) predicted the ..
  8. pmc Hepatic lipid accumulation alters global histone h3 lysine 9 and 4 trimethylation in the peroxisome proliferator-activated receptor alpha network
    Hee Jin Jun
    Department of Biotechnology, Graduate School of Life Sciences and Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea
    PLoS ONE 7:e44345. 2012
    ..Thus, control of H3K9me3 and H3K4me3 represents a potential novel NAFLD prevention and treatment strategy...
  9. pmc The polycomb group protein Bmi1 binds to the herpes simplex virus 1 latent genome and maintains repressive histone marks during latency
    Dacia L Kwiatkowski
    Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, 32610 0266, USA
    J Virol 83:8173-81. 2009
    ..To our knowledge, these are the first data demonstrating that a virus can repress its gene transcription to enter latency by exploiting the mechanism of Polycomb-mediated repression...
  10. pmc cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progression
    PEDRO RODRIGUEZ-COLLAZO
    Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Exp Cell Res 314:2855-69. 2008
    ..Here we show that cAMP signaling regulates histone H3 phosphorylation in a cell cycle-dependent fashion, increasing it in quiescent cells but dramatically reducing it ..
  11. pmc Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylation
    Mahalakshmi Nair
    Department of Biological Chemistry, University of California, Irvine, CA 92697, USA
    Dev Biol 320:446-55. 2008
    ..2, and H1fnt, all of which are required for germ cell chromatin condensation, and drastically altered pattern of histone H3 hyperacetylation...
  12. pmc Retinoblastoma tumor suppressor protein-dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit
    Alexandre Blais
    Department of Biochemistry, Microbiology, and Immunology, Ottawa Institute of Systems Biology, University of Ottawa, Ottawa K1H 8M5, Canada
    J Cell Biol 179:1399-412. 2007
    ..We further demonstrate that pRb effects permanent cell cycle exit in part by maintaining trimethylation of histone H3 lysine 27 (H3K27) on cell cycle genes...
  13. ncbi Changes in H3K79 methylation during preimplantation development in mice
    Masatoshi Ooga
    Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan
    Biol Reprod 78:413-24. 2008
    ..To elucidate the mechanisms of genome reprogramming, we investigated histone H3 lysine 79 dimethylation (H3K79me2) and trimethylation (H3K79me3) in oocytes and preimplantation embryos via ..
  14. ncbi Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome
    Shin ichi Horike
    Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mail Stop 84 171, University of California, Berkeley, California 94720, USA
    Nat Genet 37:31-40. 2005
    ..These results show that formation of a silent-chromatin loop is a new mechanism underlying gene regulation by Mecp2...
  15. ncbi Differential regulation between gene expression and histone H3 acetylation in the variable regions of the TCRbeta locus
    Lili Wang
    Department of Immunology, Tokai University School of Medicine, Bouseidai, Isehara, Kanagawa 259 1193, Japan
    Biochem Biophys Res Commun 298:420-6. 2002
    ..In this study, we investigated a role of histone H3 acetylation in transcriptional regulation of the TCRbeta locus...
  16. pmc Phosphorylation of histone H3 is functionally linked to retinoic acid receptor beta promoter activation
    Bruno Lefebvre
    Laboratory of Molecular Growth Regulation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    EMBO Rep 3:335-40. 2002
    ..were constitutively acetylated at this promoter, retinoid agonists induced a rapid phosphorylation at Ser10 of histone H3. A retinoid antagonist, whose activity was independent of co-repressor binding to RAR, could oppose this agonist-..
  17. ncbi Sak kinase gene structure and transcriptional regulation
    J W Hudson
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Canada
    Gene 241:65-73. 2000
    ..Using various Sak promoter/luciferase constructs, the core promoter region required for expression was located within 400bp of the message Cap site, and sequence further 5' strongly suppressed transcription...
  18. ncbi The mouse histone H1 genes: gene organization and differential regulation
    Z F Wang
    Department of Biology, University of North Carolina at Chapel Hill 27599, USA
    J Mol Biol 271:124-38. 1997
    ..None of the other histone H1 genes encodes detectable amounts of polyadenylated mRNAs...
  19. pmc Structure of a cluster of mouse histone genes
    D B Sittman
    Nucleic Acids Res 11:6679-97. 1983
    ..The codon usage in the genes is non-random and there has been no discrimination against CG doublets in the coding region of the genes...
  20. ncbi Mononucleotide repeats are an abundant source of length variants in mouse genomic DNA
    T J Aitman
    Nuffield Department of Surgery, John Radcliffe Hospital, Headington, Oxford, UK
    Mamm Genome 1:206-10. 1991
    ..Nine of the 18 repeat sequences (50%) have three or more alleles in the strains tested. Ten of these repeat sequences have been mapped using strain distribution patterns (SDPs) in recombinant inbred (RI) strains...
  21. ncbi IL9 maps to mouse chromosome 13 and human chromosome 5
    B A Mock
    Laboratory of Genetics, National Cancer Institute, Bethesda, MD 20892
    Immunogenetics 31:265-70. 1990
    ..Analysis of chromosome 13 alleles for Tcrg, Dhfr, and Il-9 in an interspecific cross between Mus musculus and NFS/N or C58/J mice indicates that IL9 is distal to Tcrg and proximal to Dhfr...
  22. ncbi Isolation and characterization of a mouse fully replication-dependent H1 gene within a genomic cluster of core histone genes
    Y S Yang
    Department of Biochemistry, University of Mississippi Medical Center, Jackson 39216
    J Biol Chem 262:17118-25. 1987
    ....
  23. ncbi Differential expression of two clusters of mouse histone genes
    R A Graves
    J Mol Biol 183:179-94. 1985
    ..Amino acid substitutions in some H3, H2a and H2b proteins are detected as internal cleavages in the S1 nuclease maps. All of these genes code for replication variant histone mRNAs, which are regulated in parallel with DNA synthesis...
  24. ncbi The murine gamma-chain of the T cell receptor is closely linked to a spermatocyte specific histone gene and the beige coat color locus on chromosome 13
    F L Owen
    J Immunol 137:1044-6. 1986
    ..Seven restriction enzymes identify five haplotypes of the highly polymorphic gamma-chain in mice...
  25. ncbi Sequences of four mouse histone H3 genes: implications for evolution of mouse histone genes
    J D Taylor
    J Mol Evol 23:242-9. 1986
    The sequences of four histone H3 genes coding for the replication variant proteins H3.1 and H3.2 have been determined. Three of these genes, two coding for H3.1 proteins and one for an H3...
  26. pmc Regulation of amyloid A gene expression in cultured cells
    H Y Rienhoff
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98104
    Mol Cell Biol 8:3710-6. 1988
    ..These observations suggest that conditioned medium contains a factor(s) that acts directly on hepatocytes to regulate SAA3 mRNA processing...
  27. pmc Mouse histone H2A and H2B genes: four functional genes and a pseudogene undergoing gene conversion with a closely linked functional gene
    T J Liu
    Nucleic Acids Res 15:3023-39. 1987
    ..The similarity of the nucleotide sequences in the coding regions of mouse histone genes is probably due to gene conversion events targeted precisely at the coding region...
  28. ncbi A mouse histone H1 variant, H1b, binds preferentially to a regulatory sequence within a mouse H3.2 replication-dependent histone gene
    N K Kaludov
    Department of Biological Science, Florida State University, Tallahassee, Florida 32306 3050, USA
    J Biol Chem 272:15120-7. 1997
    ..2 sequence. Our findings raise the possibility that this H1b protein plays a specific role in regulation of expression of the replication-dependent histone gene family...
  29. pmc An alternative pathway of histone mRNA 3' end formation in mouse round spermatids
    S B Moss
    Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia 19104
    Nucleic Acids Res 22:3160-6. 1994
    ....
  30. ncbi Structure of a cluster of mouse histone genes
    V D Brown
    Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill 27599, USA
    Biochim Biophys Acta 1306:17-22. 1996
    ..The sequences and levels of expression of the H3 and H2b gene as well as the sequence of the H2a pseudogene have been determined...
  31. ncbi Characterization of the mouse histone gene cluster on chromosome 13: 45 histone genes in three patches spread over 1Mb
    Z F Wang
    Department of Biology, University of North Carolina at Chapel Hill 27599 7100, USA
    Genome Res 6:688-701. 1996
    ..All nine histone H3 genes in this cluster have been sequenced, and their level of expression determined...
  32. ncbi An H3 coding region regulatory element is common to all four nucleosomal classes of mouse histone-encoding genes
    T L Bowman
    Department of Biological Science, Florida State University, Tallahassee 32306 3050, USA
    Gene 176:1-8. 1996
    ..3, has a mutated alpha element that fails to interact with nuclear proteins, suggest that this regulatory element is involved in the coordinate expression of the replication-dependent core H genes in the eukaryotic cell cycle...
  33. ncbi Chromatin modifications during oogenesis in the mouse: removal of somatic subtypes of histone H1 from oocyte chromatin occurs post-natally through a post-transcriptional mechanism
    H J Clarke
    Department of Obstetrics and Gynecology, Royal Victoria Hospital, Montreal, Quebec, Canada
    J Cell Sci 110:477-87. 1997
    ..The post-natal loss of somatic H1 appears to be regulated post-transcriptionally by a mechanism not involving nuclear localization...
  34. ncbi Genetic loci that control the angiogenic response to basic fibroblast growth factor
    Michael S Rogers
    Vascular Biology Program, Children s Hospital, and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02115, USA
    FASEB J 18:1050-9. 2004
    ..Differences in these regions may influence individual susceptibility to angiogenesis related diseases such as cancer, macular degeneration, atherosclerosis, and arthritis...
  35. ncbi Linkage analysis of 84 microsatellite markers in intra- and interspecific backcrosses
    M A McAleer
    Nuffield Department of Surgery, John Radcliffe Hospital, Headington, Oxford, UK
    Mamm Genome 3:457-60. 1992