Genomes and Genes
Gene Symbol: Hist1h3f
Description: histone cluster 1, H3f
Alias: H3.2-221, Hist1, histone H3.2, histone 1, H3f, histone H3, histone gene complex 1
- Linkage of loci associated with two pigment mutations on mouse chromosome 13R F Holcombe
Department of Medicine, LSU Medical Center, Shreveport 71130
Genet Res 58:41-50. 1991..and pe loci and the loci for the T-cell receptor gamma-chain gene (Tcrg), the spermatocyte specific histone gene (Hist1), the prolactin gene (Prl), the Friend murine leukaemia virus integration site 1 (Fim-1), the murine Hanukuh ..
- Histone H3.3 maintains genome integrity during mammalian developmentChuan Wei Jang
Department of Genetics, Carolina Center for Genome Sciences, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
Genes Dev 29:1377-92. 2015b>Histone H3.3 is a highly conserved histone H3 replacement variant in metazoans and has been implicated in many important biological processes, including cell differentiation and reprogramming. Germline and somatic mutations in H3...
- Activation of the mitogen-activated protein kinase ERK1 during meiotic progression of mouse pachytene spermatocytesC Sette
Dipartimento di Sanita Pubblica e Biologia Cellulare, Sezione di Anatomia, Universita di Roma Tor Vergata, Via O Raimondo 8, 00173, Rome, Italy
J Biol Chem 274:33571-9. 1999....
- Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repressionMidori Shimada
Department of Cell Biology and Biochemistry, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho cho, Mizuho ku, Nagoya 467 8601, Japan
Cell 132:221-32. 2008..We show here that DNA damage rapidly reduces histone H3 Threonine 11 (T11) phosphorylation. This correlates with repression of genes, including cyclin B1 and cdk1...
- Sequentially acting Sox transcription factors in neural lineage developmentMaria Bergsland
Ludwig Institute for Cancer Research, Department of Cell and Molecular Biology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
Genes Dev 25:2453-64. 2011..These data indicate that a single key transcription factor family acts sequentially to coordinate neural gene expression from the early lineage specification in pluripotent cells to later stages of neuronal development...
- Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancerLaxmi G Pellakuru
Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Pathol 181:560-9. 2012..These findings suggest that increased levels of decondensed chromatin in both normal progenitor cells and cancer cells are associated with global loss of H3K27me3, which is linked to MYC overexpression...
- Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomesChih Chi Yuan
Department of Molecular Biology, Massachusetts General Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA
Cell Rep 1:83-90. 2012The preferential in vitro interaction of the PHD finger of RAG2, a subunit of the V(D)J recombinase, with histone H3 tails simultaneously trimethylated at lysine 4 and symmetrically dimethylated at arginine 2 (H3R2me2sK4me3) predicted the ..
- Hepatic lipid accumulation alters global histone h3 lysine 9 and 4 trimethylation in the peroxisome proliferator-activated receptor alpha networkHee Jin Jun
Department of Biotechnology, Graduate School of Life Sciences and Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea
PLoS ONE 7:e44345. 2012..Thus, control of H3K9me3 and H3K4me3 represents a potential novel NAFLD prevention and treatment strategy...
- The polycomb group protein Bmi1 binds to the herpes simplex virus 1 latent genome and maintains repressive histone marks during latencyDacia L Kwiatkowski
Department of Molecular Genetics and Microbiology, University of Florida College of Medicine, Gainesville, 32610 0266, USA
J Virol 83:8173-81. 2009..To our knowledge, these are the first data demonstrating that a virus can repress its gene transcription to enter latency by exploiting the mechanism of Polycomb-mediated repression...
- cAMP signaling regulates histone H3 phosphorylation and mitotic entry through a disruption of G2 progressionPEDRO RODRIGUEZ-COLLAZO
Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Exp Cell Res 314:2855-69. 2008..Here we show that cAMP signaling regulates histone H3 phosphorylation in a cell cycle-dependent fashion, increasing it in quiescent cells but dramatically reducing it ..
- Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylationMahalakshmi Nair
Department of Biological Chemistry, University of California, Irvine, CA 92697, USA
Dev Biol 320:446-55. 2008..2, and H1fnt, all of which are required for germ cell chromatin condensation, and drastically altered pattern of histone H3 hyperacetylation...
- Retinoblastoma tumor suppressor protein-dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exitAlexandre Blais
Department of Biochemistry, Microbiology, and Immunology, Ottawa Institute of Systems Biology, University of Ottawa, Ottawa K1H 8M5, Canada
J Cell Biol 179:1399-412. 2007..We further demonstrate that pRb effects permanent cell cycle exit in part by maintaining trimethylation of histone H3 lysine 27 (H3K27) on cell cycle genes...
- Changes in H3K79 methylation during preimplantation development in miceMasatoshi Ooga
Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan
Biol Reprod 78:413-24. 2008..To elucidate the mechanisms of genome reprogramming, we investigated histone H3 lysine 79 dimethylation (H3K79me2) and trimethylation (H3K79me3) in oocytes and preimplantation embryos via ..
- Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndromeShin ichi Horike
Life Sciences Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mail Stop 84 171, University of California, Berkeley, California 94720, USA
Nat Genet 37:31-40. 2005..These results show that formation of a silent-chromatin loop is a new mechanism underlying gene regulation by Mecp2...
- Differential regulation between gene expression and histone H3 acetylation in the variable regions of the TCRbeta locusLili Wang
Department of Immunology, Tokai University School of Medicine, Bouseidai, Isehara, Kanagawa 259 1193, Japan
Biochem Biophys Res Commun 298:420-6. 2002..In this study, we investigated a role of histone H3 acetylation in transcriptional regulation of the TCRbeta locus...
- Phosphorylation of histone H3 is functionally linked to retinoic acid receptor beta promoter activationBruno Lefebvre
Laboratory of Molecular Growth Regulation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
EMBO Rep 3:335-40. 2002..were constitutively acetylated at this promoter, retinoid agonists induced a rapid phosphorylation at Ser10 of histone H3. A retinoid antagonist, whose activity was independent of co-repressor binding to RAR, could oppose this agonist-..
- Sak kinase gene structure and transcriptional regulationJ W Hudson
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Canada
Gene 241:65-73. 2000..Using various Sak promoter/luciferase constructs, the core promoter region required for expression was located within 400bp of the message Cap site, and sequence further 5' strongly suppressed transcription...
- The mouse histone H1 genes: gene organization and differential regulationZ F Wang
Department of Biology, University of North Carolina at Chapel Hill 27599, USA
J Mol Biol 271:124-38. 1997..None of the other histone H1 genes encodes detectable amounts of polyadenylated mRNAs...
- Structure of a cluster of mouse histone genesD B Sittman
Nucleic Acids Res 11:6679-97. 1983..The codon usage in the genes is non-random and there has been no discrimination against CG doublets in the coding region of the genes...
- Mononucleotide repeats are an abundant source of length variants in mouse genomic DNAT J Aitman
Nuffield Department of Surgery, John Radcliffe Hospital, Headington, Oxford, UK
Mamm Genome 1:206-10. 1991..Nine of the 18 repeat sequences (50%) have three or more alleles in the strains tested. Ten of these repeat sequences have been mapped using strain distribution patterns (SDPs) in recombinant inbred (RI) strains...
- IL9 maps to mouse chromosome 13 and human chromosome 5B A Mock
Laboratory of Genetics, National Cancer Institute, Bethesda, MD 20892
Immunogenetics 31:265-70. 1990..Analysis of chromosome 13 alleles for Tcrg, Dhfr, and Il-9 in an interspecific cross between Mus musculus and NFS/N or C58/J mice indicates that IL9 is distal to Tcrg and proximal to Dhfr...
- Isolation and characterization of a mouse fully replication-dependent H1 gene within a genomic cluster of core histone genesY S Yang
Department of Biochemistry, University of Mississippi Medical Center, Jackson 39216
J Biol Chem 262:17118-25. 1987....
- Differential expression of two clusters of mouse histone genesR A Graves
J Mol Biol 183:179-94. 1985..Amino acid substitutions in some H3, H2a and H2b proteins are detected as internal cleavages in the S1 nuclease maps. All of these genes code for replication variant histone mRNAs, which are regulated in parallel with DNA synthesis...
- The murine gamma-chain of the T cell receptor is closely linked to a spermatocyte specific histone gene and the beige coat color locus on chromosome 13F L Owen
J Immunol 137:1044-6. 1986..Seven restriction enzymes identify five haplotypes of the highly polymorphic gamma-chain in mice...
- Sequences of four mouse histone H3 genes: implications for evolution of mouse histone genesJ D Taylor
J Mol Evol 23:242-9. 1986The sequences of four histone H3 genes coding for the replication variant proteins H3.1 and H3.2 have been determined. Three of these genes, two coding for H3.1 proteins and one for an H3...
- Regulation of amyloid A gene expression in cultured cellsH Y Rienhoff
Fred Hutchinson Cancer Research Center, Seattle, Washington 98104
Mol Cell Biol 8:3710-6. 1988..These observations suggest that conditioned medium contains a factor(s) that acts directly on hepatocytes to regulate SAA3 mRNA processing...
- Mouse histone H2A and H2B genes: four functional genes and a pseudogene undergoing gene conversion with a closely linked functional geneT J Liu
Nucleic Acids Res 15:3023-39. 1987..The similarity of the nucleotide sequences in the coding regions of mouse histone genes is probably due to gene conversion events targeted precisely at the coding region...
- A mouse histone H1 variant, H1b, binds preferentially to a regulatory sequence within a mouse H3.2 replication-dependent histone geneN K Kaludov
Department of Biological Science, Florida State University, Tallahassee, Florida 32306 3050, USA
J Biol Chem 272:15120-7. 1997..2 sequence. Our findings raise the possibility that this H1b protein plays a specific role in regulation of expression of the replication-dependent histone gene family...
- An alternative pathway of histone mRNA 3' end formation in mouse round spermatidsS B Moss
Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia 19104
Nucleic Acids Res 22:3160-6. 1994....
- Structure of a cluster of mouse histone genesV D Brown
Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill 27599, USA
Biochim Biophys Acta 1306:17-22. 1996..The sequences and levels of expression of the H3 and H2b gene as well as the sequence of the H2a pseudogene have been determined...
- Characterization of the mouse histone gene cluster on chromosome 13: 45 histone genes in three patches spread over 1MbZ F Wang
Department of Biology, University of North Carolina at Chapel Hill 27599 7100, USA
Genome Res 6:688-701. 1996..All nine histone H3 genes in this cluster have been sequenced, and their level of expression determined...
- An H3 coding region regulatory element is common to all four nucleosomal classes of mouse histone-encoding genesT L Bowman
Department of Biological Science, Florida State University, Tallahassee 32306 3050, USA
Gene 176:1-8. 1996..3, has a mutated alpha element that fails to interact with nuclear proteins, suggest that this regulatory element is involved in the coordinate expression of the replication-dependent core H genes in the eukaryotic cell cycle...
- Chromatin modifications during oogenesis in the mouse: removal of somatic subtypes of histone H1 from oocyte chromatin occurs post-natally through a post-transcriptional mechanismH J Clarke
Department of Obstetrics and Gynecology, Royal Victoria Hospital, Montreal, Quebec, Canada
J Cell Sci 110:477-87. 1997..The post-natal loss of somatic H1 appears to be regulated post-transcriptionally by a mechanism not involving nuclear localization...
- Genetic loci that control the angiogenic response to basic fibroblast growth factorMichael S Rogers
Vascular Biology Program, Children s Hospital, and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02115, USA
FASEB J 18:1050-9. 2004..Differences in these regions may influence individual susceptibility to angiogenesis related diseases such as cancer, macular degeneration, atherosclerosis, and arthritis...
- Linkage analysis of 84 microsatellite markers in intra- and interspecific backcrossesM A McAleer
Nuffield Department of Surgery, John Radcliffe Hospital, Headington, Oxford, UK
Mamm Genome 3:457-60. 1992