Gpr182

Summary

Gene Symbol: Gpr182
Description: G protein-coupled receptor 182
Alias: AM-R, Admr, G10-D, Gpcr17, Gpcr22, MB10, NOW, G-protein coupled receptor 182, G10D, adrenomedullin receptor
Species: mouse

Top Publications

  1. doi Genome-wide identification of endothelial cell-enriched genes in the mouse embryo
    Haruka Takase
    Department of Anatomy and Embryology, Institute of Basic Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Japan
    Blood 120:914-23. 2012
  2. ncbi Cloning and expression of cDNA encoding a rat adrenomedullin receptor
    S Kapas
    Department of Chemical Endocrinology, Medical College, St Bartholomew s Hospital, London, United Kingdom
    J Biol Chem 270:25344-7. 1995
  3. ncbi Molecular cloning of a novel putative G protein-coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system
    Y Saeki
    Department of Neurology, Osaka University Medical School, Japan
    FEBS Lett 336:317-22. 1993
  4. ncbi Expression of adrenomedullin and its receptor during embryogenesis suggests autocrine or paracrine modes of action
    L M Montuenga
    Biomarkers and Prevention Research Branch, National Cancer Institute, Rockville, Maryland 20850, USA
    Endocrinology 138:440-51. 1997
  5. ncbi Adrenomedullin expression in the mouse mammary gland: evidence for the mature form in milk
    G D Jahnke
    Laboratory of Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Mol Endocrinol 19:279-89. 1997
  6. ncbi Expression of adrenomedullin, a hypotensive peptide, in the trophoblast giant cells at the embryo implantation site in mouse
    S Yotsumoto
    Department of Internal Medicine, Wayne State University, 5047 Gullen Mall, Detroit, Michigan, 48202, USA
    Dev Biol 203:264-75. 1998
  7. ncbi Adrenomedullin in mammalian embryogenesis
    Mercedes Garayoa
    Department of Histology and Pathology, Carcinogenesis Unit, University of Navarra, 31080 Pamplona, Spain
    Microsc Res Tech 57:40-54. 2002
  8. pmc The ADMR receptor mediates the effects of adrenomedullin on pancreatic cancer cells and on cells of the tumor microenvironment
    Vijaya Ramachandran
    Department of Cancer Biology, University of Texas MD Anderson Cancer Centre, Houston, Texas, United States of America
    PLoS ONE 4:e7502. 2009

Scientific Experts

  • L M Montuenga
  • Mercedes Garayoa
  • Haruka Takase
  • Vijaya Ramachandran
  • Kazuhiko Uchida
  • Hiromi Mochizuki
  • Ken Matsumoto
  • Hiroyuki Ishitobi
  • Masatsugu Ema
  • Ayaka Otsu
  • Takahiro Kojima
  • Yoshiaki Kubota
  • Shingo Takano
  • Rumiko Suzuki
  • Satoru Takahashi
  • Rie Yamadera
  • Craig D Logsdon
  • Pablo Vivas-Mejia
  • Rosa F Hwang
  • Gabriel Lopez-Berestein
  • Thiruvengadam Arumugam
  • Robert Langley
  • Anil K Sood
  • S Yotsumoto
  • G D Jahnke
  • S Kapas
  • T Shimada
  • H Fujiwara
  • M S Ko
  • C Y Cui
  • H Nakashima
  • F Cuttitta
  • M J Miller
  • A Martinez
  • Y Saeki
  • A J Clark
  • K J Catt
  • S Ueno
  • T Yanagihara
  • Y Nagai
  • T Nishimura
  • R Mizuno
  • H Fujimura

Detail Information

Publications8

  1. doi Genome-wide identification of endothelial cell-enriched genes in the mouse embryo
    Haruka Takase
    Department of Anatomy and Embryology, Institute of Basic Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1 1 1 Tennodai, Tsukuba, Japan
    Blood 120:914-23. 2012
    ..Thus, the genes identified in our survey show high expression in ECs; further analysis of these genes should facilitate our understanding of the molecular mechanisms of vascular development in the mouse...
  2. ncbi Cloning and expression of cDNA encoding a rat adrenomedullin receptor
    S Kapas
    Department of Chemical Endocrinology, Medical College, St Bartholomew s Hospital, London, United Kingdom
    J Biol Chem 270:25344-7. 1995
    ..We report here the identification of a cDNA clone for the adrenomedullin receptor that was originally isolated as an orphan receptor from rat lung...
  3. ncbi Molecular cloning of a novel putative G protein-coupled receptor (GPCR21) which is expressed predominantly in mouse central nervous system
    Y Saeki
    Department of Neurology, Osaka University Medical School, Japan
    FEBS Lett 336:317-22. 1993
    ....
  4. ncbi Expression of adrenomedullin and its receptor during embryogenesis suggests autocrine or paracrine modes of action
    L M Montuenga
    Biomarkers and Prevention Research Branch, National Cancer Institute, Rockville, Maryland 20850, USA
    Endocrinology 138:440-51. 1997
    ..In several regions of the embryo, the patterns of AM expression correspond to the degree of differentiation. The possible involvement of AM in the control of embryonic invasion, proliferation, and differentiation is discussed...
  5. ncbi Adrenomedullin expression in the mouse mammary gland: evidence for the mature form in milk
    G D Jahnke
    Laboratory of Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Mol Endocrinol 19:279-89. 1997
    ..These data suggest a potential role for AM and its receptor in the maintenance of mammary gland homeostasis and suggests a potential role for AM in development of the newborn...
  6. ncbi Expression of adrenomedullin, a hypotensive peptide, in the trophoblast giant cells at the embryo implantation site in mouse
    S Yotsumoto
    Department of Internal Medicine, Wayne State University, 5047 Gullen Mall, Detroit, Michigan, 48202, USA
    Dev Biol 203:264-75. 1998
    ..Although it has been well established that a major production site of AM is vascular endothelial cells, we now show that AM is most highly expressed in trophoblast giant cells, which are derived from the conceptus and are ..
  7. ncbi Adrenomedullin in mammalian embryogenesis
    Mercedes Garayoa
    Department of Histology and Pathology, Carcinogenesis Unit, University of Navarra, 31080 Pamplona, Spain
    Microsc Res Tech 57:40-54. 2002
    ....
  8. pmc The ADMR receptor mediates the effects of adrenomedullin on pancreatic cancer cells and on cells of the tumor microenvironment
    Vijaya Ramachandran
    Department of Cancer Biology, University of Texas MD Anderson Cancer Centre, Houston, Texas, United States of America
    PLoS ONE 4:e7502. 2009
    ..The current study examines the role of specific AM receptors on tumor and cells resembling the tumor microenvironment (human pancreatic stellate--HPSC, human umbilical vein-- HUVEC and mouse lung endothelial cells--MLEC)...