Glo1

Summary

Gene Symbol: Glo1
Description: glyoxalase 1
Alias: 0610009E22Rik, 1110008E19Rik, 2510049H23Rik, AW550643, GLY1, Glo-1, Glo-1r, Glo-1s, Glo1-r, Glo1-s, Qglo, lactoylglutathione lyase, S-D-lactoylglutathione methylglyoxal lyase, aldoketomutase, glx I, glyoxalase 1 complex, glyoxalase 1 regulatory, glyoxalase 1 structural, glyoxalase I, ketone-aldehyde mutase, methylglyoxalase
Species: mouse

Top Publications

  1. ncbi Genetic control of the quantitative variation of erythrocytic glyoxalase-1(GLO-1) in mice
    P Rubinstein
    Biochem Genet 20:153-63. 1982
  2. ncbi Mouse mitochondrial superoxide dismutase locus is on chromosome 17
    J M Szymura
    Immunogenetics 14:231-40. 1981
  3. pmc Characterisation of glyoxalase I in a streptozocin-induced mouse model of diabetes with painful and insensate neuropathy
    M M Jack
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Diabetologia 54:2174-82. 2011
  4. ncbi Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety
    Simone A Krömer
    Max Planck Institute of Psychiatry, D 80804 Munich, Germany
    J Neurosci 25:4375-84. 2005
  5. ncbi Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice
    Iiris Hovatta
    The Salk Institute for Biological Studies, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nature 438:662-6. 2005
  6. ncbi Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r)
    K Ganesh Kumar
    Division of Experimental Obesity, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808 4124, USA
    Am J Physiol Regul Integr Comp Physiol 292:R207-16. 2007
  7. ncbi Glyoxalase I polymorphism in the mouse: a new genetic marker linked to H-2
    T Meo
    Science 198:311-3. 1977
  8. ncbi High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A
    Dachun Yao
    Juvenile Diabetes Research Foundation International Center for Diabetic Complications Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Biol Chem 282:31038-45. 2007
  9. pmc A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior
    Richard Williams
    Committee on Computational Neuroscience, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 4:e4649. 2009
  10. pmc Hyperglycemia impairs proteasome function by methylglyoxal
    Markus A Queisser
    School of Medicine, Institute of Biochemistry, Justus Liebig University, Giessen, Germany
    Diabetes 59:670-8. 2010

Scientific Experts

  • C K Haston
  • Samina Salim
  • Michael Brownlee
  • Margaret G Distler
  • Naila Rabbani
  • Dachun Yao
  • Markus Wortmann
  • F Hosoda
  • Hong Zhang
  • Stephan Herzig
  • Peter P Nawroth
  • Min Jea Shin
  • Ferdinando Giacco
  • Guang Yang
  • Thomas H Fleming
  • Lorenz K Kollmannsberger
  • Cailu Lin
  • Ki Mo Kim
  • M M Jack
  • Alexander Kurz
  • Mireille Belanger
  • Greta Sokoloff
  • Abraham A Palmer
  • Markus A Queisser
  • Paul J Thornalley
  • M Takeuchi
  • Richard Williams
  • Hans Peter Hammes
  • Makoto Kawatani
  • Marcus Hollenbach
  • K Ganesh Kumar
  • Michelle T Barati
  • Magdalena M Staniszewska
  • Xinhua Yu
  • Maike F de Buhr
  • Iiris Hovatta
  • Simone A Krömer
  • Andreas S Peters
  • Tjeerd P Sijmonsma
  • Maani Hakimi
  • Thomas Fleming
  • Dittmar Böckler
  • Susanne Dihlmann
  • Li Ping Zhang
  • M Ohki
  • M Miyamoto
  • H Katai
  • Yun Yun Chen
  • Qiang Huang
  • Y Arai
  • J Inazawa
  • Ren Wei Zhang
  • Jing Zhai
  • H Shimizu
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  • Yi ning Zhao
  • Qing Li
  • Xiao Peng Hu
  • N Okada
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  • H Taniguchi
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  • Xueliang Du
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Detail Information

Publications59

  1. ncbi Genetic control of the quantitative variation of erythrocytic glyoxalase-1(GLO-1) in mice
    P Rubinstein
    Biochem Genet 20:153-63. 1982
  2. ncbi Mouse mitochondrial superoxide dismutase locus is on chromosome 17
    J M Szymura
    Immunogenetics 14:231-40. 1981
    ..Since a similar locus in the human is linked to HLA, the human major histocompatibility complex, extensive homology must exist between the mouse and human MHC-bearing chromosomes...
  3. pmc Characterisation of glyoxalase I in a streptozocin-induced mouse model of diabetes with painful and insensate neuropathy
    M M Jack
    Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA
    Diabetologia 54:2174-82. 2011
    ..The enzyme glyoxalase I (GLO1) detoxifies reactive dicarbonyls that form AGEs and may affect the way sensory neurons respond to ..
  4. ncbi Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety
    Simone A Krömer
    Max Planck Institute of Psychiatry, D 80804 Munich, Germany
    J Neurosci 25:4375-84. 2005
    ..Additional studies will examine whether glyoxalase-I has an impact beyond that of a biomarker to predict the genetic predisposition to anxiety- and depression-like behavior...
  5. ncbi Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice
    Iiris Hovatta
    The Salk Institute for Biological Studies, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, California 92037, USA
    Nature 438:662-6. 2005
    ..Both of these genes are involved in oxidative stress metabolism, linking this pathway with anxiety-related behaviour...
  6. ncbi Quantitative trait loci for carbohydrate and total energy intake on mouse chromosome 17: congenic strain confirmation and candidate gene analyses (Glo1, Glp1r)
    K Ganesh Kumar
    Division of Experimental Obesity, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808 4124, USA
    Am J Physiol Regul Integr Comp Physiol 292:R207-16. 2007
    ..Positional gene candidates with relevance to carbohydrate metabolism, glyoxalase I (Glo1) and glucagon-like peptide-1 receptor (Glp1r), were evaluated...
  7. ncbi Glyoxalase I polymorphism in the mouse: a new genetic marker linked to H-2
    T Meo
    Science 198:311-3. 1977
    Two electrophoretically distinct variants of glyoxalase I (Glo-I) are present in mouse (Mus musculus). The two forms are controlled by two codominant alleles Glo-1a (common) and Glo-1b (rare) at an autosomal locus...
  8. ncbi High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A
    Dachun Yao
    Juvenile Diabetes Research Foundation International Center for Diabetic Complications Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Biol Chem 282:31038-45. 2007
    ..This novel mechanism for regulating gene expression may play a role in the pathobiology of diabetic vascular disease...
  9. pmc A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior
    Richard Williams
    Committee on Computational Neuroscience, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 4:e4649. 2009
    Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans...
  10. pmc Hyperglycemia impairs proteasome function by methylglyoxal
    Markus A Queisser
    School of Medicine, Institute of Biochemistry, Justus Liebig University, Giessen, Germany
    Diabetes 59:670-8. 2010
    ..In this study, the influence of MGO-derived advanced glycation end product (AGE) formation on the activity of the proteasome was investigated in vitro and in vivo...
  11. doi Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose
    Ki Mo Kim
    Diabetic Complications Research Center, Division of Traditional Korean Medicine TKM Integrated Research, Korea Institute of Oriental Medicine KIOM, 483 Exporo, Yuseong Gu, Daejeon 305 811, South Korea
    Exp Cell Res 318:152-9. 2012
    ..These results suggest that GLO-1 plays a role in high glucose-mediated signaling by reducing MG accumulation and oxidative stress in diabetes mellitus...
  12. pmc Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal
    Margaret G Distler
    Department of Pathology, University of Chicago, Chicago, Illinois 60637, USA
    J Clin Invest 122:2306-15. 2012
    Glyoxalase 1 (Glo1) expression has previously been associated with anxiety in mice; however, its role in anxiety is controversial, and the underlying mechanism is unknown...
  13. pmc A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice
    Markus Wortmann
    Department of Vascular and Endovascular Surgery, University of Heidelberg, 69120 Heidelberg, Germany
    J Diabetes Res 2016:2981639. 2016
    ..Yet, the role of Glo1 in atherosclerosis remains unclear...
  14. doi Aging-dependent reduction in glyoxalase 1 delays wound healing
    Thomas H Fleming
    Department of Medicine I and Clinical Chemistry, University of Heidelberg, Heidelberg, Germany
    Gerontology 59:427-37. 2013
    Methylglyoxal (MG), the major dicarbonyl substrate of the enzyme glyoxalase 1 (GLO1), is a reactive metabolite formed via glycolytic flux...
  15. pmc QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects
    Cailu Lin
    Monell Chemical Senses Center, Philadelphia Pennsylvania, USA
    PLoS ONE 8:e68776. 2013
    ..of filtering methods highlighted seven candidate genes within the QTL locus boundaries: Crx, Dmpk, Ahr, Mrpl28, Glo1, Tubb5, and Mut...
  16. pmc Increased glyoxalase-1 levels in Fkbp5 knockout mice caused by glyoxalase-1 gene duplication
    Lorenz K Kollmannsberger
    Max Planck Institute of Psychiatry, 80804 Munich, Germany
    G3 (Bethesda) 3:1311-3. 2013
    ..We found that these mice carry a gene duplication of glyoxylase-1, which explains why glyoxylase-1 levels are increased in the Fkbp5 knockout mice. ..
  17. pmc Structural basis for 18-β-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor
    Hong Zhang
    School of Pharmaceutical Sciences and Centre for Cellular and Structural Biology of Sun Yat sen University, Guangzhou 510006, China
    Acta Pharmacol Sin 36:1145-50. 2015
    b>Glyoxalase I (GLOI), a glutathione (GSH)-dependent enzyme, is overexpressed in tumor cells and related to multi-drug resistance in chemotherapy, making GLOI inhibitors as potential anti-tumor agents...
  18. pmc Knockdown of glyoxalase 1 mimics diabetic nephropathy in nondiabetic mice
    Ferdinando Giacco
    Diabetes Research Center, Albert Einstein College of Medicine, Bronx, NY
    Diabetes 63:291-9. 2014
    ..Overexpression of the enzyme glyoxalase 1 (Glo1), which prevents posttranslational modification of proteins by the glycolysis-derived α-oxoaldehyde, methylglyoxal ..
  19. doi Tat-glyoxalase protein inhibits against ischemic neuronal cell damage and ameliorates ischemic injury
    Min Jea Shin
    Department of Biomedical Sciences and Research Institute of Bioscience and Biotechnology, Hallym University, Chunchon 200 702, Korea
    Free Radic Biol Med 67:195-210. 2014
    ..Therefore, we investigated the protective effect of GLO (GLO1 and GLO2) in neuronal cells and an animal ischemia model using Tat-GLO proteins...
  20. doi An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program
    Guang Yang
    Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, ON M5G 1L7, Canada
    Neuron 84:723-39. 2014
    ..Thus, neural precursors are transcriptionally primed to generate neurons, but an eIF4E/4E-T complex sequesters and represses translation of proneurogenic proteins to determine appropriate neurogenesis...
  21. doi Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer
    F Hosoda
    Division of Cancer Genomics, National Cancer Center Research Institute, Tokyo, Japan
    Oncogene 34:1196-206. 2015
    ..Among these six candidates, GLO1, encoding a detoxifying enzyme glyoxalase I (GLO1), exhibited the strongest tumor-forming activity...
  22. doi Role of the glyoxalase system in astrocyte-mediated neuroprotection
    Mireille Belanger
    Laboratory of Neuroenergetics and Cellular Dynamics, Brain Mind Institute, Ecole Polytechnique Federale de Lausanne, CH 1015 Lausanne, Switzerland
    J Neurosci 31:18338-52. 2011
    ..Accordingly, the neuroenergetic specialization taking place between these two cell types may serve as a protective mechanism against MG-induced neurotoxicity...
  23. pmc Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE
    Franky Van Herreweghe
    Department of Medical Protein Research, Ghent University and Flanders Interuniversity Institute for Biotechnology, K L Ledeganckstraat 35, B 9000 Ghent, Belgium
    Proc Natl Acad Sci U S A 99:949-54. 2002
    ..Here we report that TNF induces an increased phosphorylation of glyoxalase I that is mediated by protein kinase A and required for cell death...
  24. pmc Murine candidate bleomycin induced pulmonary fibrosis susceptibility genes identified by gene expression and sequence analysis of linkage regions
    C K Haston
    Meakins Christie Laboratories, Department of Medicine, McGill Centre for Bioinformatics, McGill University, Montreal, Canada
    J Med Genet 42:464-73. 2005
    ..In a prior study, susceptibility to bleomycin induced pulmonary fibrosis was mapped to loci Blmpf1 and Blmpf2 on chromosomes 17 and 11, respectively, in a C57BL/6J (B6, susceptible) and C3Hf/KAM (C3H, resistant) mouse cross...
  25. ncbi Upregulation of glyoxalase I fails to normalize methylglyoxal levels: a possible mechanism for biochemical changes in diabetic mouse lenses
    Magdalena M Staniszewska
    Department of Ophthalmology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
    Mol Cell Biochem 288:29-36. 2006
    b>Glyoxalase I is the first enzyme in a two-enzyme glyoxalase system that metabolizes physiological methylglyoxal (MGO)...
  26. ncbi Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses
    Maike F de Buhr
    Central Animal Facility, Institute for Laboratory Animal Science, Hannover Medical School, Hannover, Germany
    Physiol Genomics 25:426-34. 2006
    ..In conclusion, the large number of candidate genes was reduced to three major candidates that play an important role in inflammatory processes and immune response. Strain differences for them are already known or are shown in this study...
  27. ncbi Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line
    Xinhua Yu
    Immunogenetics Group, University of Rostock, Rostock, Germany
    J Immunol 177:7042-9. 2006
    ..In addition, this study revealed that Cia27 and Trmq3 controlling anti-CII IgG2a Ab and CD4:CD8 T cell ratio, respectively, also regulated CIA clinical phenotypes...
  28. ncbi Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice
    Michelle T Barati
    Department of Medicine, University of Louisville, Louisville, Kentucky 40202, USA
    Am J Physiol Renal Physiol 293:F1157-65. 2007
    ..However, activity of glutathione peroxidase and SOD was unaltered in glomeruli of diabetic mice. Expression of glyoxalase I was increased in glomeruli of diabetic mice...
  29. doi Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors
    Marcus Hollenbach
    University of Leipzig, Institute of Biochemistry, Johannisallee 30, 04103 Leipzig, Germany
    Biochem Pharmacol 76:631-44. 2008
    ..In vitro enzyme activity measurements revealed the inhibition of human Glo1 by alpha-oxo-carbonic acid esters, whilst alpha-hydroxy-carbonic acid esters such as EL were not inhibitory...
  30. pmc The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I
    Makoto Kawatani
    Antibiotics Laboratory, Chemical Biology Department, and Biomolecular Characterization Team, Advanced Technology Support Division, Advanced Science Institute, RIKEN, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    Proc Natl Acad Sci U S A 105:11691-6. 2008
    ..By using M-GFN-immobilized beads, glyoxalase I (GLO1) was identified as an M-GFN-binding protein...
  31. doi Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment
    M Takeuchi
    Department of Transfusion Medicine and Cell Therapy, Kyoto University Hospital, Kyoto, Japan
    Cell Death Differ 17:1211-20. 2010
    ....
  32. pmc Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress
    Alexander Kurz
    Department of Neurology, Section Molecular Neurogenetics, Goethe University Medical School, Frankfurt am Main, Germany
    Cell Mol Life Sci 68:721-33. 2011
    ..of knock-out mice at different ages with regard to consistent upregulations of the transcriptome and focused on glyoxalase I (GLO1). The microarray data were confirmed in qPCR, immunoblot, enzyme activity, and behavior analyses...
  33. pmc Novel role of RGS2 in regulation of antioxidant homeostasis in neuronal cells
    Samina Salim
    Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, USA
    FEBS Lett 585:1375-81. 2011
    ..Our study is the first to suggest role of RGS2 in regulation of enzymes involved in antioxidant defense namely glyoxalase-1 and glutathione reductase-1 via activation of p38 MAPK and PKC pathways in an Sp-1 dependent manner...
  34. ncbi The locus controlling liver GM1(NeuGc) expression is mapped 1 cM centromeric to H-2K
    M Sakaizumi
    Tokyo Metropolitan Institute of Medical Science, Japan
    Immunogenetics 27:57-60. 1988
    ..Ggm-1 was mapped 1 cM centromeric to H-2K on chromosome 17...
  35. ncbi Assignment of a Mus musculus gene for triosephosphate isomerase to chromosome 6 and for glyoxalase-I to chromosome 17 using somatic cell hybrids
    J D Minna
    Somatic Cell Genet 4:241-52. 1978
    ..This finding adds to the number of autosomal gene pairs which are syntenic in both mouse and man and reinforces the belief that there is considerable conservation. of linkage groups during evolution...
  36. ncbi Assignment of the gene for glyoxylase I to mouse chromosome 17 by somatic cell genetics
    L Leinwand
    Biochem Genet 16:659-66. 1978
    ..The presence of chromosome 17 and expression of GLO I were concordant in 31/31 clones. GLO I is thus linked to the H-2 histocompatibility locus in the mouse...
  37. ncbi Conservation of autosomal gene synteny groups in mouse and man
    P A Lalley
    Nature 274:160-3. 1978
  38. ncbi Chromosomal localization of the murine gene and two related sequences encoding high-mobility-group I and Y proteins
    K R Johnson
    Jackson Laboratory, Bar Harbor, Maine 04609
    Genomics 12:503-9. 1992
    ..Hmgi genes have not been previously mapped in any species, but the location of the probable functional gene on murine Chromosome 17 suggests that the homologous gene in humans is located on Chromosome 6...
  39. ncbi Assignment of the homolog of the MAS1 oncogene to mouse chromosome 17
    M R Al-Ubaidi
    Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030
    Genomics 13:487. 1992
  40. ncbi Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci
    J H Nadeau
    Jackson Laboratory, Bar Harbor, Maine 04609
    Genomics 9:78-89. 1991
    ....
  41. ncbi Localization of a mouse heat shock Hsp70 gene within the H-2 complex
    H R Gaskins
    Jackson Laboratory, Bar Harbor, ME 04609
    Immunogenetics 32:286-9. 1990
  42. ncbi The rat MHC and cystathionine beta-synthase gene are syntenic on chromosome 20
    J Locker
    University of Pittsburgh, School of Medicine, Department of Pathology, PA 15261
    Immunogenetics 31:271-4. 1990
  43. pmc Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17
    S V Cheng
    Neurogenetics Laboratory, Massachusetts General Hospital, Boston
    Proc Natl Acad Sci U S A 85:6032-6. 1988
    ..The break in synteny between the terminal portion of human chromosome 21 and mouse chromosome 16 indicates, however, that mouse trisomy 16 may not represent a complete model of DS...
  44. pmc Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human
    C Blatt
    Weizmann Institute, Rehovoth, Israel
    Proc Natl Acad Sci U S A 85:7642-6. 1988
    ..These mapping assignments will be useful in defining the extent of the G alpha gene family and may help in attempts to correlate specific genetic diseases with genes corresponding to G proteins...
  45. ncbi Genetic mapping of Pim-1 putative oncogene to mouse chromosome 17
    J Hilkens
    Somat Cell Mol Genet 12:81-8. 1986
    ..The Pim-1 gene was localized on chromosome 17, a chromosome frequently aberrant in T-cell lymphomas. Two chromosomal regions, containing sequences homologous to regions within the Pim-1 locus, were localized on chromosome 6 and 16...
  46. ncbi Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse
    O Heidmann
    Science 234:866-8. 1986
    ....
  47. ncbi The location of the C3 and GLO (glyoxalase 1) loci of the IXth linkage group in mice
    P Rubinstein
    J Immunol 122:2584-9. 1979
  48. pmc A glyoxalase-1 variant associated with the t-complex in house mice
    J H Nadeau
    Genetics 113:91-9. 1986
    ..Thus, this variant of Glo-1c provides both a further example of gametic disequilibrium between the t-complex and linked loci and a readily identifiable marker for the t-complex...
  49. ncbi Electrophoretic analysis of liver neuraminidase-1 variation in mice and additional evidence concerning the location of NEU-1
    P B Samollow
    J Immunogenet 13:29-39. 1986
    ..Recombination rates among six H-2-linked marker loci were unexpectedly low, but were sufficient to verify the position of Upg-1 as the telomeric flanking marker relative to Glo-1, H-2 (C4), Neu-1 (Apl), Ce-2 and Pgk-2...
  50. pmc Mouse alpha-globin genes and alpha-globin-like pseudogenes are not syntenic
    R A Popp
    Proc Natl Acad Sci U S A 78:6362-6. 1981
    ..These data explain why alpha-3 and alpha-4 were not affected by the three independently induced deletion-type mutations that cause alpha-thalassemia in the mouse...
  51. ncbi Genetic mapping in mammals: chromosome map of domestic cat
    S J O'Brien
    Science 216:257-65. 1982
    ..Many of these same linkage groups have not been conserved in the murine genome. The genetic and evolutionary implications of comparative mapping analysis among mammalian species are discussed...
  52. ncbi Mouse gene for neuraminidase activity (Neu-1) maps to the D end of H-2
    J E Womack
    Immunogenetics 16:177-80. 1982
  53. ncbi Confirmational, provisional, and/or regional assignment of 15 enzyme loci onto Chinese hamster autosomes 1, 2, and 7
    R L Stallings
    Somatic Cell Genet 7:683-98. 1981
    ..The assignments provide markers for the study of the genetic consequences of chromosomal rearrangements in Chinese hamster cell lines and support the concept of conservation of mammalian autosomal linkage groups...
  54. ncbi Assignment of the gene for cytoplasmic glutamate-oxaloacetate transaminase to mouse chromosome 19 using chinese hamster x mouse somatic cell hybrids
    R Schafer
    Somatic Cell Genet 6:709-17. 1980
    ..The appearance of a heteropolymeric band in hybrid cells expressing mouse GOT-1 suggests that this enzyme molecule is probably composed of two subunits...
  55. ncbi A closely linked complex of mouse mast cell-specific chymase genes on chromosome 14
    M F Gurish
    Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115
    J Biol Chem 268:11372-9. 1993
    ....
  56. ncbi H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17
    J Klein
    Immunogenetics 16:285-317. 1982
  57. ncbi Linkage map of mouse chromosome 17: localization of 27 new DNA markers
    V Vincek
    Max Planck Institut fur Biologie, Abteilung Immungenetik, Tubingen, Federal Republic of Germany
    Genomics 5:773-86. 1989
    ..The distal region of MMU17, on the other hand, is populated by only a few, rather imprecisely mapped markers. Molecular maps are available for most of the H-2 complex and for parts of the t complex...
  58. ncbi Strain distribution pattern for SSLP markers in the SWXJ recombinant inbred strain set: chromosomes 7 to X
    K L Shultz
    Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA
    Mamm Genome 7:526-32. 1996
    ..Combined with the 165 loci for Chr 1-6 reported previously (Svenson et al., Mamm. Genome 6, 867, 1995), the SWXJ RI set represents a powerful tool for mapping genes in neoplastic as well as other heritable disorders...
  59. ncbi Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9
    R T Bronson
    The Jackson Laboratory, Bar Harbor, Maine, USA
    Am J Med Genet 77:289-97. 1998
    ....