Art1

Summary

Gene Symbol: Art1
Description: ADP-ribosyltransferase 1
Alias: ADPRT, ARTC1, Yac-1, GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1, ADP-ribosyltransferase C2 and C3 toxin-like 1, mono(ADP-ribosyl)transferase 1
Species: mouse

Top Publications

  1. doi ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-κB pathway
    Ming Xiao
    Department of Pathology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China
    Cell Physiol Biochem 32:1587-99. 2013
  2. doi Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells
    Jing Kuang
    Department of Pathology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, P R China
    Oncol Rep 31:2335-43. 2014
  3. pmc Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway
    Lian Yang
    Department of Pathology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, P R China
    Int J Mol Med 37:734-42. 2016
  4. doi NAD induces astrocyte calcium flux and cell death by ART2 and P2X7 pathway
    Jianbiao Wang
    Department of Pathology, Zhejiang University School of Medicine, Hangzhou, China
    Am J Pathol 181:746-52. 2012
  5. ncbi Cloning and characterization of a novel membrane-associated lymphocyte NAD:arginine ADP-ribosyltransferase
    I J Okazaki
    Pulmonary Critical Care Medicine Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 271:22052-7. 1996
  6. ncbi Molecular characterization of a glycosylphosphatidylinositol-linked ADP-ribosyltransferase from lymphocytes
    I J Okazaki
    Pulmonary Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1434, USA
    Blood 88:915-21. 1996
  7. ncbi Assignment of the human and mouse genes for muscle ecto mono (ADPribosyl)transferase to a conserved linkage group on human chromosome 11p15 and mouse chromosome 7
    F Koch-Nolte
    Department of Immunology, University Hospital, Hamburg, 20246, Federal Republic of Germany
    Genomics 36:215-6. 1996
  8. ncbi Prostate cancer progression, metastasis, and gene expression in transgenic mice
    C Perez-stable
    Veterans Affairs Medical Center, and Department of Medicine, University of Miami School of Medicine, Florida 33101, USA
    Cancer Res 57:900-6. 1997
  9. ncbi Molecular cloning of a functional murine arginine-specific mono-ADP-ribosyltransferase and its expression in lymphoid cells
    Y Yu
    Department of Molecular Microbiology and Immunology, USC Norris Comprehensive Cancer Center, University of Southern California School of Medicine, Los Angeles 90033, USA
    DNA Cell Biol 16:235-44. 1997
  10. pmc Molecular characterization and expression of the gene for mouse NAD+:arginine ecto-mono(ADP-ribosyl)transferase, Art1
    R Braren
    Institute for Immunology, University Hospital, Martinistr 52, D 20246 Hamburg, Germany
    Biochem J 336:561-8. 1998

Scientific Experts

  • Ming Xiao
  • Lian Yang
  • Yi Tang
  • Ya Lan Wang
  • Jing Kuang
  • Xian Li
  • Guang Lin Song
  • Jianbiao Wang
  • F Koch-Nolte
  • G Glowacki
  • R Braren
  • Christelle Bourgeois
  • F Haag
  • Xi Yang
  • Ming Li
  • Wen Wen Chen
  • Gustavo Glowacki
  • I J Okazaki
  • Junhua Yang
  • Xiwen Bi
  • Cui Li
  • Puqing Liu
  • Keqing Zhu
  • E H Leiter
  • M Cetkovic-Cvrlje
  • Y Yu
  • C Perez-stable
  • Joel Moss
  • Ian Okazaki
  • Eleanor Cavanaugh
  • Maria Nightingale
  • Pedro Reche
  • Maren Kühl
  • H J Kim
  • Friedrich Haag
  • Friedrich Koch-Nolte
  • Edward Leiter
  • J Moss
  • Fernando Bazan
  • Kathrin Firner
  • Rickmer Braren
  • Marion Nissen
  • Marina Cetkovic-Cvrlje
  • M Nissen
  • L J Deftos
  • B A Roos
  • E Nemoto
  • N H Altman
  • P P Mehta
  • S Okamoto
  • G Dennert
  • N G McElvaney
  • M Kuhl
  • H G Thiele
  • E Lesma

Detail Information

Publications13

  1. doi ART1 silencing enhances apoptosis of mouse CT26 cells via the PI3K/Akt/NF-κB pathway
    Ming Xiao
    Department of Pathology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China
    Cell Physiol Biochem 32:1587-99. 2013
    ..Arginine ADP-ribosyltransferase 1(ART1) is an important ecto-ADP-ribose transferase and has been proven to be intimately involved in a number of ..
  2. doi Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells
    Jing Kuang
    Department of Pathology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, P R China
    Oncol Rep 31:2335-43. 2014
    Arginine-specific ADP-ribosyltransferase 1 (ART1) and poly(ADP-ribose) polymerase-1 (PARP-1) are both post‑translational modification proteins...
  3. pmc Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway
    Lian Yang
    Department of Pathology, Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing 400016, P R China
    Int J Mol Med 37:734-42. 2016
    Arginine adenosine diphosphate (ADP)-ribosyl-transferase 1 (ART1) is known to play an important role in many physiological and pathological processes...
  4. doi NAD induces astrocyte calcium flux and cell death by ART2 and P2X7 pathway
    Jianbiao Wang
    Department of Pathology, Zhejiang University School of Medicine, Hangzhou, China
    Am J Pathol 181:746-52. 2012
    ..The results suggest a novel approach for manipulating astrocyte death...
  5. ncbi Cloning and characterization of a novel membrane-associated lymphocyte NAD:arginine ADP-ribosyltransferase
    I J Okazaki
    Pulmonary Critical Care Medicine Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 271:22052-7. 1996
    ....
  6. ncbi Molecular characterization of a glycosylphosphatidylinositol-linked ADP-ribosyltransferase from lymphocytes
    I J Okazaki
    Pulmonary Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1434, USA
    Blood 88:915-21. 1996
    ..Thus, we have cloned a novel gene that has properties identical to the transferase detected in CTL, and may be involved in the NAD-dependent regulation of proliferation and cytotoxicity...
  7. ncbi Assignment of the human and mouse genes for muscle ecto mono (ADPribosyl)transferase to a conserved linkage group on human chromosome 11p15 and mouse chromosome 7
    F Koch-Nolte
    Department of Immunology, University Hospital, Hamburg, 20246, Federal Republic of Germany
    Genomics 36:215-6. 1996
  8. ncbi Prostate cancer progression, metastasis, and gene expression in transgenic mice
    C Perez-stable
    Veterans Affairs Medical Center, and Department of Medicine, University of Miami School of Medicine, Florida 33101, USA
    Cancer Res 57:900-6. 1997
    ..We propose the Ggamma/T-15 transgenic line as a model of highly aggressive androgen-independent metastatic prostate carcinoma with features similar to end-stage prostate cancer in humans...
  9. ncbi Molecular cloning of a functional murine arginine-specific mono-ADP-ribosyltransferase and its expression in lymphoid cells
    Y Yu
    Department of Molecular Microbiology and Immunology, USC Norris Comprehensive Cancer Center, University of Southern California School of Medicine, Los Angeles 90033, USA
    DNA Cell Biol 16:235-44. 1997
    A protein mono-ADP-ribosyltransferase (ADPRT), anchored in the cell membrane as a glycosylphosphatidylinositol (GPI)-anchored cell-surface enzyme, was recently described on murine cytotoxic T cells (CTL)...
  10. pmc Molecular characterization and expression of the gene for mouse NAD+:arginine ecto-mono(ADP-ribosyl)transferase, Art1
    R Braren
    Institute for Immunology, University Hospital, Martinistr 52, D 20246 Hamburg, Germany
    Biochem J 336:561-8. 1998
    ..We have characterized the gene for mouse arginine-specific ADP-ribosyltransferase, Art1. Southern blot analyses indicate that Art1 is a single-copy gene...
  11. ncbi Structure, chromosomal localization, and expression of the gene for mouse ecto-mono(ADP-ribosyl)transferase ART5
    G Glowacki
    Institute for Immunology, University Hospital, Martinistrasse 52, 20246 Hamburg, Germany
    Gene 275:267-77. 2001
    ..6 cM in close proximity to the Art1, Art2a and Art2b genes...
  12. pmc The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse
    Gustavo Glowacki
    Institute of Immunology, University Hospital, Martinistrasse 52, D 20246 Hamburg, Germany
    Protein Sci 11:1657-70. 2002
    ..This suggests that the two enzyme families that catalyze reversible mono-ADP-ribosylation either were lost from the genomes of these nonchordata eucaryotes or were subject to horizontal gene transfer between kingdoms...
  13. ncbi Identification of regulatory domains in ADP-ribosyltransferase-1 that determine transferase and NAD glycohydrolase activities
    Christelle Bourgeois
    Pulmonary Critical Care Medicine Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892 1590, USA
    J Biol Chem 278:26351-5. 2003
    Mono-ADP-ribosyltransferases (ART1-7) transfer ADP-ribose from NAD+ to proteins (transferase activity) or water (NAD glycohydrolase activity)...