Amy1

Summary

Gene Symbol: Amy1
Description: amylase 1, salivary
Alias: Amy-1, Amy1a, C030014B17Rik, alpha-amylase 1, 1,4-alpha-D-glucan glucanohydrolase 1, salivary and hepatic alpha-amylase
Species: mouse

Top Publications

  1. ncbi AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex
    Makoto Furusawa
    Graduate School of Pharmaceutical Sciences, College of Medical Technology, Hokkaido University, Kita ku, Sapporo 060 0812, Japan
    J Biol Chem 277:50885-92. 2002
  2. pmc Low Copy Number of the AMY1 Locus Is Associated with Early-Onset Female Obesity in Finland
    Heli Viljakainen
    Children s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
    PLoS ONE 10:e0131883. 2015
  3. ncbi Assignment of the mouse homologues of 6 loci from HSA1p to chromosomes 3 and 4
    P J McClive
    Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Victoria, Australia
    Genomics 23:243-6. 1994
  4. ncbi The genes encoding gonadal and nongonadal forms of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase are closely linked on mouse chromosome 3
    P A Bain
    Graduate Program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor 48109
    Genomics 16:219-23. 1993
  5. ncbi Ampd-2 maps to distal mouse chromosome 3 in linkage with Ampd-1
    W S Moseley
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710
    Genomics 6:572-4. 1990
  6. ncbi Rostral cerebellar malformation, (rcm): a new recessive mutation on chromosome 3 of the mouse
    P W Lane
    Jackson Laboratory, Bar Harbor, Maine
    J Hered 83:315-8. 1992
  7. pmc Mind bomb 1 is required for pancreatic β-cell formation
    Signe Horn
    Department of Developmental Biology, Hagedorn Research Institute, DK 2820 Gentofte, Denmark
    Proc Natl Acad Sci U S A 109:7356-61. 2012
  8. doi Runx/Cbfb signaling regulates postnatal development of granular convoluted tubule in the mouse submandibular gland
    Md Nurul Islam
    Department of Orthodontics, Science of Functional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Dev Dyn 244:488-96. 2015
  9. pmc Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity
    Christina L Usher
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    Nat Genet 47:921-5. 2015
  10. ncbi Altered salivary amylase gene in the mouse strain BXD-16
    J P Hjorth
    Heredity (Edinb) 48:127-35. 1982

Scientific Experts

  • Christina L Usher
  • Heli Viljakainen
  • Md Nurul Islam
  • Signe Horn
  • Takayoshi Sakai
  • Hiroshi Kamioka
  • Han Cao
  • Carlos N Pato
  • Tadashi Honjo
  • Noriaki Kawanabe
  • Michael Boehnke
  • Timothy M Frayling
  • Joel N Hirschhorn
  • Satoru Hayano
  • Hiroshi Kurosaka
  • Kumi Sumiyoshi
  • Steven A McCarroll
  • Minna Pekkinen
  • Alex R Hastie
  • Koh ichi Kuremoto
  • Outi Makitie
  • Helena Valta
  • Mark I McCarthy
  • Seva Kashin
  • Anna Lindstrand
  • Marcus A Tuke
  • Michele T Pato
  • Miriam Armenio
  • Johanna C Andersson-Assarsson
  • Ichiro Taniuchi
  • David M Altshuler
  • Takeshi Yanagita
  • Andres Metspalu
  • Marita Lipsanen-Nyman
  • Tõnu Esko
  • Naozumi Ishimaru
  • Shinsuke Itoh
  • Takashi Yamashiro
  • Robert E Handsaker
  • Maria Pettersson
  • Jennifer E Moon
  • Michael N Weedon
  • Christian Fuchsberger
  • Makoto Furusawa
  • Heiko Lickert
  • Mark A Magnuson
  • Young Yun Kong
  • Jan N Jensen
  • Sune Kobberup
  • Mark Kalisz
  • Mette C Jørgensen
  • Moritz Gegg
  • Ryoichiro Kageyama
  • Jill Lindner
  • Tino Klein
  • Jonas Ahnfelt-Rønne
  • Palle Serup
  • E Lammert
  • C A Kozak
  • K R Johnson
  • B Sosa-Pineda
  • S Cook
  • P A Schweitzer
  • Hiroyoshi Ariga
  • Sanae M M Iguchi-Ariga
  • J O Minta
  • R J Tolwani
  • Takahiro Taira
  • J Brown
  • Y Li
  • A Sjodin
  • D A Melton
  • T E Broad
  • J Bhalerao
  • M H Meisler
  • P J McClive
  • A G Kumar
  • Y C Cheah
  • C Mülhardt
  • O Hagenbuchle
  • K N Pandey
  • D S Threadgill
  • B A Taylor
  • J H Nadeau
  • M T Davisson
  • M Torres
  • K Chowdhury
  • J L Guenet
  • P Gruss
  • M Davisson

Detail Information

Publications71

  1. ncbi AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex
    Makoto Furusawa
    Graduate School of Pharmaceutical Sciences, College of Medical Technology, Hokkaido University, Kita ku, Sapporo 060 0812, Japan
    J Biol Chem 277:50885-92. 2002
    ..These findings suggest that AMY-1 is an important modulator of PKA...
  2. pmc Low Copy Number of the AMY1 Locus Is Associated with Early-Onset Female Obesity in Finland
    Heli Viljakainen
    Children s Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
    PLoS ONE 10:e0131883. 2015
    The salivary α-amylase locus (AMY1) is located in a highly polymorphic multi allelic copy number variable chromosomal region. A recent report identified an association between AMY1 copy numbers and BMI in common obesity...
  3. ncbi Assignment of the mouse homologues of 6 loci from HSA1p to chromosomes 3 and 4
    P J McClive
    Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Victoria, Australia
    Genomics 23:243-6. 1994
    ..Furthermore, an additional HSA1p marker, Cd53, mapped close to Amy1 on mouse chromosome 3, and a sequence related to Lap18 mapped to mouse chromosome 17, near D17Mit3...
  4. ncbi The genes encoding gonadal and nongonadal forms of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase are closely linked on mouse chromosome 3
    P A Bain
    Graduate Program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor 48109
    Genomics 16:219-23. 1993
    ..The order of markers on Chr 3 surrounding Hsd3b is: centromere-Gba-(4.4 +/- 2.2)-Hsd3b-(3.3 +/- 1.9)-Tshb-(6.7 +/- 2.7)-Amy-1...
  5. ncbi Ampd-2 maps to distal mouse chromosome 3 in linkage with Ampd-1
    W S Moseley
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710
    Genomics 6:572-4. 1990
  6. ncbi Rostral cerebellar malformation, (rcm): a new recessive mutation on chromosome 3 of the mouse
    P W Lane
    Jackson Laboratory, Bar Harbor, Maine
    J Hered 83:315-8. 1992
    ..The mutation, called rostral cerebellar malformation, rcm, has been located on chromosome (Chr) 3 between the alcohol dehydrogenase-3 (Adh-3) complex and varitint waddler-J (VaJ)...
  7. pmc Mind bomb 1 is required for pancreatic β-cell formation
    Signe Horn
    Department of Developmental Biology, Hagedorn Research Institute, DK 2820 Gentofte, Denmark
    Proc Natl Acad Sci U S A 109:7356-61. 2012
    ..Our results reveal iterative use of Notch in pancreatic development to ensure correct P-D patterning and adequate β-cell formation...
  8. doi Runx/Cbfb signaling regulates postnatal development of granular convoluted tubule in the mouse submandibular gland
    Md Nurul Islam
    Department of Orthodontics, Science of Functional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Dev Dyn 244:488-96. 2015
    ..The rodent salivary gland is not fully developed at birth and the cellular definitive differentiation takes place postnatally. However, little is known about its molecular mechanism...
  9. pmc Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity
    Christina L Usher
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    Nat Genet 47:921-5. 2015
    ..One such region contains the three amylase genes (AMY2B, AMY2A and AMY1) responsible for digesting starch into sugar...
  10. ncbi Altered salivary amylase gene in the mouse strain BXD-16
    J P Hjorth
    Heredity (Edinb) 48:127-35. 1982
    ..This indicates that only a single structural gene for the enzyme is expressed in the strain BXD-16...
  11. ncbi Genetic determination of amylase synthesis in the mouse
    J H Bloor
    J Biol Chem 256:373-7. 1981
    ..Congenic lines with different amylase phenotypes have been established. Genetic analysis reveals the close linkage of cis-acting sites determining rate of synthesis and electrophoretic mobility of mouse pancreatic amylase...
  12. ncbi Murine VCAM-1. Molecular cloning, mapping, and analysis of a truncated form
    A G Kumar
    Department of Internal Medicine, Baylor College of Medicine, Houston, TX 77030
    J Immunol 153:4088-98. 1994
    ..the murine Vcam1 gene including 3 kb of 5'-flanking sequences and mapped the gene to chromosome 3 near Amy1. cDNA clones isolated from a stimulated hepatic library were found to encode a truncated form of VCAM-1 (T-VCAM-1) ..
  13. ncbi Mouse R-cadherin: expression during the organogenesis of pancreas and gastrointestinal tract
    A Sjodin
    Department of Microbiology, University of Umea, Sweden
    Exp Cell Res 221:413-25. 1995
    ..The subcellular localization in these tissues is on both the apical and basolateral surfaces. The potential function of R-cadherin, in particular its role in pancreas development, is discussed...
  14. ncbi Esterase-26 (ES-26): characterization and genetic location on chromosome 3 of an eserine-sensitive esterase of the house mouse (Mus musculus)
    O H von Deimling
    Biochem Genet 22:1119-26. 1984
    ..The enzyme was shown to be controlled by the presumed structural locus Es-26, located on chromosome 3. From a four-point cross, the gene order Car-2--6.2 +/- 2.7--Es-16--21.0 +/- 4.5--Es-26--13.6 +/- 3.8--Amy-1 was established...
  15. ncbi Independent regulation of nonallelic pancreatic amylase genes in diabetic mice
    A Dranginis
    J Biol Chem 259:12216-9. 1984
    ..The results provide genetic evidence that individual copies of the amylase structural gene are associated with divergent cis-acting insulin-responsive sequences...
  16. ncbi Linkage relationships among eleven biochemical loci in Peromyscus
    W D Dawson
    Biochem Genet 21:1101-14. 1983
    ..These and other known linkage relationships in Peromyscus correspond closely to those of the house mouse, Mus musculus. The available evidence in Peromyscus further supports the concept of linkage conservation by natural selection...
  17. ncbi The mouse alpha-amylase multigene family. Sequence organization of members expressed in the pancreas, salivary gland and liver
    U Schibler
    J Mol Biol 155:247-66. 1982
  18. ncbi Multiple structural genes for mouse amylase
    J P Hjorth
    Biochem Genet 18:281-302. 1980
    ..We conclude that at least four structural genes code for pancreatic amylase while only a single gene, different from any of the pancreatic genes, codes for salivary amylase...
  19. pmc Multiple polyadenylation sites in a mouse alpha-amylase gene
    M Tosi
    Nucleic Acids Res 9:2313-23. 1981
    ..Sequences which trail the two polyadenylation sites exhibit extensive homology and might therefore be involved in polyadenylation or transcription termination...
  20. ncbi Characterization of the amino termini of mouse salivary and pancreatic amylases
    R C Karn
    FEBS Lett 126:293-6. 1981
  21. ncbi Additional evidence for the close linkage of amy-1 and amy-2 in the mouse
    J H Bloor
    J Hered 71:449-51. 1980
    ..Among 343 potentially recombinant chromosomes examined, no recombinants were found. Our data sets an upper limit of 0.87 cM (P = 0.95) for the distance between the salivary and pancreatic loci...
  22. ncbi A single mouse alpha-amylase gene specifies two different tissue-specific mRNAs
    R A Young
    Cell 23:451-8. 1981
    ..genome, indicating that both the salivary gland and liver alpha-amylase mRNAs are transcribed from the same gene (Amy1A)...
  23. ncbi Mouse liver and salivary gland alpha-amylase mRNAs differ only in 5' non-translated sequences
    O Hagenbuchle
    Nature 289:643-6. 1981
    ..These data suggest that all three mRNAs might be transcribed from the same gene...
  24. ncbi Molecular cloning, characterization, and genetic mapping of the cDNA coding for a novel secretory protein of mouse. Demonstration of alternative splicing in skin and cartilage
    J Bhalerao
    Department of Biochemistry, University of Antwerp, Belgium
    J Biol Chem 270:16385-94. 1995
    ..Alternative splicing may serve as a mechanism for generating functional diversity in the Ecm1 gene...
  25. ncbi A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis
    Y Li
    Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115
    Cell 80:423-30. 1995
    ..The results also suggest that the normal differentiation and spatial organization of growth plate chondrocytes is critially dependent on the presence of type XI collagen in cartilage extracellular matrix...
  26. ncbi The spastic mouse: aberrant splicing of glycine receptor beta subunit mRNA caused by intronic insertion of L1 element
    C Mülhardt
    Zentrum fur Molekulare Biologie, Universitat Heidelberg, Federal Republic of Germany
    Neuron 13:1003-15. 1994
    ..Intron 5 of the spa Glyrb gene contains an L1 transposable element that apparently is causal for the aberrant splicing of beta subunit transcripts...
  27. ncbi Genetic mapping of the gene encoding guanylate cyclase-A/atrial natriuretic factor receptor (Npra) to mouse chromosome 3
    K N Pandey
    Department of Biochemistry and Molecular Biology, Medical College of Georgia, School of Medicine, Augusta 30912 2100
    Mamm Genome 5:520-2. 1994
  28. ncbi Syntenic assignment of human chromosome 1 homologous loci in the bovine
    D S Threadgill
    Department of Veterinary Pathobiology, Texas A and M University, College Station 77843
    Genomics 22:626-30. 1994
    ..AT3, REN, CR2, and GNB1 mapped to BTA 16, PFKM to BTA 5, AMY1A and NRAS to BTA 3, FGR and FUCA1 to BTA 2, and ACTA1 to BTA 28.
  29. ncbi Mapping of glutathione transferase (GST) genes in the rat
    K Klinga-Levan
    Department of Genetics, Gothenburg University, Sweden
    Hereditas 119:285-96. 1993
    ..Interestingly, each of the three groups of conserved synteny seems to span the region across the centromeres of the human chromosomes...
  30. ncbi Four loci from human chromosome 1 are physically assigned to sheep chromosome 1p
    T E Broad
    AgResearch Grasslands Research Centre, Palmerston North, New Zealand
    Mamm Genome 6:551-3. 1995
  31. ncbi cDNA cloning, sequencing and chromosomal assignment of the gene for mouse complement factor I (C3b/C4b inactivator): identification of a species specific divergent segment in factor I
    J O Minta
    Department of Cellular and Molecular Pathology, University of Toronto, Canada
    Mol Immunol 33:101-12. 1996
    ..The significance of the diversity of the D segment is at present unclear. We also report the chromosomal localization of the mouse factor I gene (Cfi) to distal chromosome 3 near Egf...
  32. ncbi Genetic mapping of the IL-12 alpha chain gene (Il12a) on mouse chromosome 3
    P A Schweitzer
    The Jackson Laboratory, Bar Harbor, Maine 04609, USA
    Mamm Genome 7:394-5. 1996
  33. ncbi Structure and chromosomal location of the mouse medium-chain acyl-CoA dehydrogenase-encoding gene and its promoter
    R J Tolwani
    Department of Comparative Medicine, School of Medicine, University of Alabama at Birmingham 35294 0019, USA
    Gene 170:165-71. 1996
    ..Biol. Chem. 268 (1993) 13805-13810]. We have mapped mouse Acadm to the distal end of chromosome 3. Sequences previously localized to chromosome 8 are shown to be a pseudogene, and an additional pseudogene was identified on chromosome 11...
  34. ncbi The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas
    B Sosa-Pineda
    Max Planck Institute for Biophysical Chemistry, Gottingen, Germany
    Nature 386:399-402. 1997
    ..A default pathway would explain the elevated number of alpha cells in the absence of Pax4...
  35. ncbi The mouse urate oxidase gene, Uox, maps to distal chromosome 3
    S Cook
    The Jackson Laboratory, Bar Harbor, Maine, 04609, USA
    Mamm Genome 8:623-4. 1997
  36. ncbi Notch gene expression during pancreatic organogenesis
    E Lammert
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Mech Dev 94:199-203. 2000
    ..Notch 3 and Notch 4 are expressed in pancreatic mesenchyme and later in endothelial cells. Together these descriptive data comprise a framework for understanding the cellular basis for Notch function during pancreatic development...
  37. ncbi Expression of calcyclin, a calcium-binding protein, in the keratogenous region of growing hair follicles
    L Wood
    Molecular Biology Research, Upjohn Company, Kalamazoo, Michigan 49001
    J Invest Dermatol 96:383-7. 1991
    ....
  38. pmc A salivary amylase transgene is efficiently expressed in liver but not in parotid gland of transgenic mice
    J M Jones
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618
    Nucleic Acids Res 17:6613-23. 1989
    ..The results also demonstrate that non-parotid sources can produce a normal level of AMY1 in serum. Liver is the probable source of AMY1 in serum of these transgenic mice.
  39. ncbi Analysis of the mouse Amy locus in recombinant inbred mouse strains
    P R Paul
    Department of Molecular and Cellular Biology, Roswell Park Memorial Institute, Buffalo, New York 14263
    Biochem Genet 25:569-79. 1987
    ..Previously reported differences for strains YBR and CE have been confirmed. New segregation data for carbonic anhydrase, a locus near the proximal end of mouse chromosome 3, are presented...
  40. ncbi Mapping and gene order of U1 small nuclear RNA, endogenous viral env sequence, amylase, and alcohol dehydrogenase-3 on mouse chromosome 3
    C Blatt
    Agouron Institute, La Jolla, California
    Somat Cell Mol Genet 14:133-42. 1988
    ..In situ hybridization to chromosome spreads confirmed the assignment of the Ulb small nuclear RNA (snRNA) gene cluster and the gamma-fibrinogen gene to the center of chromosome 3...
  41. pmc Simultaneous expression of salivary and pancreatic amylase genes in cultured mouse hepatoma cells
    G J Darlington
    Mol Cell Biol 6:969-75. 1986
    ..We speculate that induction of Amy-1 and activation of Amy-2 may involve different regulatory mechanisms. Hepa 1-6 cells provide an experimental system for molecular analysis of these events...
  42. pmc A 78-kilobase region of mouse chromosome 3 contains salivary and pancreatic amylase genes and a pseudogene
    K Wiebauer
    Proc Natl Acad Sci U S A 82:5446-9. 1985
    ..A truncated amylase pseudogene is located 10 kilobases downstream from the pancreatic amylase gene...
  43. ncbi Chromosomal localization of the mouse genes coding for alpha 2, alpha 3, alpha 4 and beta 2 subunits of neuronal nicotinic acetylcholine receptor
    A Bessis
    UA CNRS D1284, Departement des Biotechnologies, Institut Pasteur, Paris, France
    FEBS Lett 264:48-52. 1990
    ..14, 9 and 3 respectively. Moreover, the alpha 4 subunit gene is located on chromosome 2 but is not genetically linked to the alpha 1 subunit gene...
  44. ncbi Genetic regulation of GM4(NeuAc) expression in mouse erythrocytes
    K Nakamura
    Department of Membrane Biochemistry, Tokyo Metropolitan Institute of Medical Science
    J Biochem 107:3-7. 1990
    ....
  45. ncbi Biochemical and genetic characterization of esterase-27 (ES-27), the major plasma cholinesterase of the house mouse (Mus musculus)
    O H von Deimling
    Abteilung für Chemische Pathologie, Universitat Freiburg, Bundesrepublik Deutschland
    Genet Res 57:61-70. 1991
    ..From a three-point cross (AKR/Han, A/Wy) and a five-point cross (AKR/Han, SEG/1), the gene order on chromosome 3 was concluded to be centromere-Car-2-Es-26-Es-27-Amy-1-Adh-1...
  46. ncbi Assignment of LH XVI to chromosome 3 in the mouse
    E M Eicher
    J Hered 71:315-8. 1980
    ..The genetic location of the breakpoint in the reciprocal translocation T(2:3)24H is placed between the Amy-1 and Va loci. A new simplified method for determining the Amy-1 and Amy-2 genotype of mice is presented...
  47. ncbi Multilocus markers for mouse genome analysis: PCR amplification based on single primers of arbitrary nucleotide sequence
    J H Nadeau
    Jackson Laboratory, Bar Harbor, Maine 04609
    Mamm Genome 3:55-64. 1992
    ..Finally, linkage for seven products was established on five chromosomes. These characteristics establish single primer PCR as a powerful method for mouse genome analysis...
  48. ncbi Structure of the murine tissue factor gene. Chromosome location and conservation of regulatory elements in the promoter
    N Mackman
    Department of Immunology, Scripps Research Institute, La Jolla, CA 92037
    Arterioscler Thromb 12:474-83. 1992
    ....
  49. ncbi Gentic polymorphism of amylase isoenzymes in feral populations of the house mouse
    J T Nielsen
    Hereditas 79:279-86. 1975
  50. ncbi Linkage of the cadmium resistance locus to loci on mouse chromosome 12
    B A Taylor
    J Hered 67:389-90. 1976
    ..A 3-point cross involving Va, cdm, and amylase-1 (Amy-1) indicated the following gene order and approximate distances: Va-8-cdm-17-Amy-1. The cdm locus is the first polymorphic locus to be placed on Chromosome 12...
  51. ncbi Gene order in linkage group XVI of the house mouse
    P W Lane
    J Hered 70:239-44. 1979
    ..We conclude that LG XVI is not carried on Chr 12, and preliminary data indicates it is most likely carried on Chr 3...
  52. ncbi Genetics of hydroxyacid oxidase isozymes in the mouse: localisation of Hao-2 on linkage group XVI
    R S Holmes
    Heredity (Edinb) 41:403-6. 1978
    ..9 +/- 2.4 per cent recombinants) in this organism, which places Hao-2 on linkage group XVI, since previous studies by Eicher and co-workers (1976) have localised Amy-1 on this chromosome...
  53. ncbi Genetic variation in mouse salivary amylase rate of synthesis
    J P Hjorth
    Biochem Genet 17:665-82. 1979
    ..Studies of other mouse strains suggest that regulatory genetic elements may modulate salivary amylase production...
  54. ncbi [Genetic analysis of interspecific crosses Mus musculus L. x Mus spretus Lataste: linkage of Adh-1 with Amy-1 on chromosome 3 and Es-14 with Mod-1 on chromosome 9]
    F Bonhomme
    C R Seances Acad Sci D 289:545-8. 1979
    ..Linkage of ES-14 with Mod-1 on chromosome 9 and that of Adh-1 with Amy-1 on chromosome 3 are shown. The following order centromere/Car-2/Amy-1 is tentatively proposed for these loci on chromosome 3...
  55. ncbi Tissue-specific expression of mouse-alpha-amylase genes: nucleotide sequence of isoenzyme mRNAs from pancreas and salivary gland
    O Hagenbuchle
    Cell 21:179-87. 1980
    ..This observation may have implications for the mechanism of translation initiation in eucaroytes...
  56. ncbi Electrophoretic variation of alpha-amylase in two inbred strains of Mus musculus
    R D Kaplan
    J Hered 64:155-7. 1973
  57. ncbi The two promoters of the mouse alpha-amylase gene Amy-1a are differentially activated during parotid gland differentiation
    P Shaw
    Cell 40:907-12. 1985
    ..The pattern of committing cells during differentiation suggests that once an acinar cell has initiated expression of parotid-type alpha-amylase mRNA, this commitment is passed on to its daughter cells...
  58. ncbi cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I)
    C J Saris
    J Biol Chem 262:10663-71. 1987
    ..Sequence homology between p11 and the S100 proteins, and the serum-induced 2A9 gene product, as well as possible functions of p11 are discussed...
  59. ncbi Members of the Amy-2 alpha-amylase gene family of mouse strain CE/J contain duplicated 5' termini
    S Bodary
    J Mol Biol 182:1-10. 1985
    ..No transcription initiation has been detected at the orphon cap site using run-off transcription in isolated pancreatic nuclei in vitro...
  60. ncbi Chromosomal locations of genes encoding 2',3' cyclic nucleotide 3'-phosphodiesterase and glial fibrillary acidic protein in the mouse
    L Bernier
    Department of Biochemistry, McGill University, Montreal, Quebec, Canada
    J Neurosci Res 20:497-504. 1988
    ..We have localized the GFAP gene to distal chromosome 11 in the mouse. There are two genetic loci identified by CNP probes, one is closely linked to the GFAP gene, and the other maps to chromosome 3...
  61. pmc Fim-1, Fim-2/c-fms, and Fim-3, three common integration sites of Friend murine leukemia virus in myeloblastic leukemias, map to mouse chromosomes 13, 18, and 3, respectively
    B Sola
    Institut National de la Santé et de la Recherche Médicale U152 Centre National de la Recherche Scientifique, UA628, Hopital Cochin, Paris, France
    J Virol 62:3973-8. 1988
    ..Fim-2 spans the 5' end of the c-fms gene, which encodes for the macrophage-colony-stimulating factor receptor. We located the c-fms gene on the D band of chromosome 18 by in situ hybridization...
  62. ncbi Chromosomal location of Evi-1, a common site of ecotropic viral integration in AKXD murine myeloid tumors
    M L Mucenski
    NCI Frederick Cancer Research Facility, BRI Basic Research Program, Maryland 21701
    Oncogene Res 2:219-33. 1988
    ..These results suggest that Evi-1 represents a new locus involved in myeloid disease...
  63. ncbi The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships
    D A Sweetser
    Department of Biological Chemistry, Washington University School of Medicine, St Louis, Missouri 63110
    J Biol Chem 262:16060-71. 1987
    ..The I-FABP gene is located on mouse chromosome 3 between the amylase 1,2 (Amy 1,2) and alcohol dehydrogenase 3 (Adh-3) loci while the L-FABP gene is on mouse chromosome 6 within 3 centimorgans ..
  64. ncbi The murine M-CSF gene is localized on chromosome 3
    S Gisselbrecht
    Institut National de la Santé et de la Recherche Médicale U152, Hopital Cochin, Paris, France
    Blood 73:1742-5. 1989
  65. ncbi New murine polymorphisms detected by random amplified polymorphic DNA (RAPD) PCR and mapped by use of recombinant inbred strains
    Y C Cheah
    Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030
    Mamm Genome 5:762-7. 1994
    ..The 10 primers were also used to survey 20 inbred mouse strains including the progenitors of other recombinant inbred sets and four mouse strains recently inbred from the wild (CAST/Ei, MOLF/Ei, PERA/Ei, and SPRET/Ei)...
  66. ncbi Genetic mapping of the murine gene and 14 related sequences encoding chromosomal protein HMG-14
    K R Johnson
    Jackson Laboratory, Bar Harbor, Maine 04609
    Mamm Genome 3:625-32. 1992
    ..Thus, the Hmg14 multigene family is well suited to serve as genetic markers for other linkage studies in mice...
  67. ncbi A mouse linkage testing stock possessing multiple copies of the endogenous ecotropic murine leukemia virus genome
    B A Taylor
    Jackson Laboratory, Bar Harbor, Maine 04609
    Genomics 5:221-32. 1989
    ..Ways of further improving the MEV stock are discussed. The location of the Myb proto-oncogene is defined relative to Sl and one of the C58/J proviruses on chromosome 10...