Abcb7

Summary

Gene Symbol: Abcb7
Description: ATP-binding cassette, sub-family B (MDR/TAP), member 7
Alias: AA517758, AU019072, Abc7, ATP-binding cassette sub-family B member 7, mitochondrial, ABC transporter 7 protein, ATP-binding cassette 7, ATP-binding cassette transporter 7
Species: mouse

Top Publications

  1. pmc Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster
    Stephen L Clarke
    Department of Nutritional Sciences, University of Wisconsin, Madison, WI 53706, USA
    EMBO J 25:544-53. 2006
  2. doi Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency
    Alain Martelli
    Translational Medecine and Neurogenetics, Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, 67400 Illkirch, France INSERM, U596, 67400 Illkirch, France CNRS, UMR7104, 67400 Illkirch, France Université de Strasbourg, 67000 Strasbourg, France Collège de France, Chaire de Génétique Humaine, 67400 Illkirch, France Electronic address
    Cell Metab 21:311-22. 2015
  3. ncbi Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human
    S Savary
    Centre d Immunologie, INSERM CNRS de Marseille Luminy, France
    Genomics 41:275-8. 1997
  4. ncbi A mutation in a mitochondrial ABC transporter results in mitochondrial dysfunction through oxidative damage of mitochondrial DNA
    H Senbongi
    Cellular and Molecular Biology Laboratory, RIKEN Institute, Saitama, Japan
    Mol Gen Genet 262:426-36. 1999
  5. ncbi Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus
    L M Schriml
    Human Genetics Section, Laboratory of Genomic Diversity, National Cancer Institute Frederick Cancer Research and Development Center, Frederick, MD 21702, USA
    Genomics 64:24-31. 2000
  6. ncbi Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase
    Shigeru Taketani
    Department of Biotechnology, Kyoto Institute of Technology, Japan
    Blood 101:3274-80. 2003
  7. ncbi The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis
    Corinne Pondarre
    Department of Pathology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Hum Mol Genet 15:953-64. 2006
  8. pmc Abcb7, the gene responsible for X-linked sideroblastic anemia with ataxia, is essential for hematopoiesis
    Corinne Pondarre
    Department of Pathology, Children s Hospital Boston, 320 Longwood Avenue, Boston, MA 02115, USA
    Blood 109:3567-9. 2007
  9. pmc Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation
    Sundeep Kalantry
    Department of Genetics, and Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Nature 460:647-51. 2009
  10. doi Dual mitochondrial localization and different roles of the reversible reaction of mammalian ferrochelatase
    Masayoshi Sakaino
    Department of Biotechnology, Kyoto Institute of Technology, Japan
    FEBS J 276:5559-70. 2009

Scientific Experts

  • Alain Martelli
  • S Taketani
  • Corinne Pondarre
  • Sundeep Kalantry
  • Mark D Fleming
  • Stephen L Clarke
  • Lucy H Williams
  • Joshua Starmer
  • Terry Magnuson
  • Masayoshi Sakaino
  • Dean R Campagna
  • Richard S Eisenstein
  • Sheila A Anderson
  • Kathryn M Deck
  • L M Schriml
  • Sakihito Kitajima
  • Ryuichi Masaki
  • Sonya Purushothaman
  • Akitsugu Yamamoto
  • Yoshiko Ohgari
  • Mutsumi Ishigaki
  • Randall Bryant Bowen
  • H Senbongi
  • Brendan Antiochos
  • M Dean
  • Howard Mulhern
  • Lindsay Sikorski
  • An Ping Han
  • Brendan B Antiochos
  • Eric L Greer
  • Aparna Vasanthakumar
  • Joseph S Pitula
  • Jeffery L Kutok
  • Amy Medlock
  • Alice McDonald
  • Charles J Epstein
  • Cheryl M Koh
  • S Savary
  • T Shibata
  • F Ling
  • M G Mattei
  • F Denizot
  • G Chimini
  • M F Luciani
  • R Allikmets

Detail Information

Publications11

  1. pmc Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster
    Stephen L Clarke
    Department of Nutritional Sciences, University of Wisconsin, Madison, WI 53706, USA
    EMBO J 25:544-53. 2006
    ..Our results reveal a mechanism for regulating IRP1 action relevant to the control of iron homeostasis during cell proliferation, inflammation, and in response to diseases altering cytosolic Fe-S cluster assembly or disassembly...
  2. doi Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency
    Alain Martelli
    Translational Medecine and Neurogenetics, Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, 67400 Illkirch, France INSERM, U596, 67400 Illkirch, France CNRS, UMR7104, 67400 Illkirch, France Université de Strasbourg, 67000 Strasbourg, France Collège de France, Chaire de Génétique Humaine, 67400 Illkirch, France Electronic address
    Cell Metab 21:311-22. 2015
    ..Our results uncover an unexpected protective role of IRP1 in pathological conditions associated with altered Fe-S metabolism...
  3. ncbi Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human
    S Savary
    Centre d Immunologie, INSERM CNRS de Marseille Luminy, France
    Genomics 41:275-8. 1997
    ..identification and genomic mapping of a novel member of the family of the ATP-binding cassette (ABC) transporters, ABC7, conserved in mouse and in humans...
  4. ncbi A mutation in a mitochondrial ABC transporter results in mitochondrial dysfunction through oxidative damage of mitochondrial DNA
    H Senbongi
    Cellular and Molecular Biology Laboratory, RIKEN Institute, Saitama, Japan
    Mol Gen Genet 262:426-36. 1999
    ..These observations indicate that spontaneous induction of petites in the atm1-1 mutant is a consequence of oxidative damage to mitochondrial DNA mediated by enhanced accumulation of mitochondrial iron...
  5. ncbi Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus
    L M Schriml
    Human Genetics Section, Laboratory of Genomic Diversity, National Cancer Institute Frederick Cancer Research and Development Center, Frederick, MD 21702, USA
    Genomics 64:24-31. 2000
    ..The mouse ABC genes could be grouped into the seven previously described human ABC subfamilies. Three mouse ABC genes mapped to regions implicated in cholesterol gallstone susceptibility...
  6. ncbi Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase
    Shigeru Taketani
    Department of Biotechnology, Kyoto Institute of Technology, Japan
    Blood 101:3274-80. 2003
    A mitochondrial half-type ATP-binding cassette (ABC) protein, ABC7, plays a role in iron homeostasis in mitochondria, and defects in human ABC7 were shown to be responsible for the inherited disease X-linked sideroblastic anemia/ataxia...
  7. ncbi The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis
    Corinne Pondarre
    Department of Pathology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Hum Mol Genet 15:953-64. 2006
    ..The mitochondrial ABC half-transporter Abcb7, which is mutated in X-linked sideroblastic anemia with ataxia in humans, is a functional ortholog of yeast Atm1p ..
  8. pmc Abcb7, the gene responsible for X-linked sideroblastic anemia with ataxia, is essential for hematopoiesis
    Corinne Pondarre
    Department of Pathology, Children s Hospital Boston, 320 Longwood Avenue, Boston, MA 02115, USA
    Blood 109:3567-9. 2007
    ..with spinocerebellar ataxia, and is due to mutations in the mitochondrial ATP-binding cassette transporter Abcb7. Here, we show that Abcb7 is essential for hematopoiesis and formally demonstrate that XLSA/A is due to partial ..
  9. pmc Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation
    Sundeep Kalantry
    Department of Genetics, and Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599 7264, USA
    Nature 460:647-51. 2009
    ..Xp-linked gene silencing associated with mouse imprinted XCI, therefore, can initiate in the embryo independently of Xist RNA...
  10. doi Dual mitochondrial localization and different roles of the reversible reaction of mammalian ferrochelatase
    Masayoshi Sakaino
    Department of Biotechnology, Kyoto Institute of Technology, Japan
    FEBS J 276:5559-70. 2009
    ....
  11. pmc Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse inner cell mass
    Lucy H Williams
    Department of Genetics, Carolina Center for Genome Sciences, and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599 7264, USA
    Development 138:2049-57. 2011
    ....