ZNF469

Summary

Gene Symbol: ZNF469
Description: zinc finger protein 469
Alias: BCS, BCS1, zinc finger protein 469
Species: human

Top Publications

  1. pmc Deleterious mutations in the Zinc-Finger 469 gene cause brittle cornea syndrome
    Almogit Abu
    Danek Gertner Institute of Human Genetics, Sheba Medical Center, Tel Hashomer 52621, Israel
    Am J Hum Genet 82:1217-22. 2008
  2. doi Brittle cornea syndrome associated with a missense mutation in the zinc-finger 469 gene
    Anne E Christensen
    Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway
    Invest Ophthalmol Vis Sci 51:47-52. 2010
  3. pmc Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness
    Yi Lu
    Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Australia
    PLoS Genet 6:e1000947. 2010
  4. doi New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8
    Veronique Vitart
    MRC Human Genetics Unit, IGMM, Edinburgh, UK
    Hum Mol Genet 19:4304-11. 2010
  5. pmc Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance
    Emma M M Burkitt Wright
    Genetic Medicine Research Group, Manchester Biomedical Research Centre, Manchester Academic Health Sciences Centre, University of Manchester and Central Manchester Foundation Trust, St Mary s Hospital, Manchester M13 9WL, UK
    Am J Hum Genet 88:767-77. 2011
  6. doi Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness
    Rene Hoehn
    Department of Ophthalmology, University Medical Center Mainz, Langenbeckstr 1, 55131 Mainz, Germany
    Hum Genet 131:1783-93. 2012
  7. doi Identification of a novel ZNF469 mutation in a large family with Ehlers-Danlos phenotype
    Mohammed Al-Owain
    Department of Medical Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Gene 511:447-50. 2012
  8. pmc Breast cancer outcomes among older women: HMO, fee-for-service, and delivery system comparisons
    A Lee-Feldstein
    Center for Health Policy and Research, Department of Medicine, College of Medicine, University of California, Irvine, Calif 92697-5800, USA
    J Gen Intern Med 16:189-99. 2001
  9. pmc Copper chelation-induced reduction of the biological activity of S-nitrosothiols
    M P Gordge
    Institute of Urology, University College London
    Br J Pharmacol 114:1083-9. 1995
  10. ncbi [Clinical manifestation and patho-typing of biliary cast syndrome in patients after orthotopic liver transplantation]
    Xiao Dan Zhu
    Institute of Liver Transplantation, General Hospital of Chinese Armed Police Forces, Beijing 100039, China
    Zhonghua Wai Ke Za Zhi 46:728-32. 2008

Research Grants

  1. Characterization of HIN1 Putative Tumor Suppressor
    Ian Krop; Fiscal Year: 2003
  2. Frank Pajonk; Fiscal Year: 2016
  3. Nirmala Ramanujam; Fiscal Year: 2015
  4. MULTILEVEL COMPLIANCE MODEL OF BREAST CANCER TREATMENTS
    Mary Fennell; Fiscal Year: 1999
  5. SHABBIR BAKIR BAMBOT; Fiscal Year: 2014
  6. Intra-operative specimen tomosynthesis for margin assessment in breast surgery
    EMRE TOKER; Fiscal Year: 2009
  7. CARE, COSTS AND OUTCOMES OF LOCAL BREAST CANCER
    Jeanne Mandelblatt; Fiscal Year: 1999
  8. A Fluorescence Histology System for In Vivo Breast Tumor Margin Assessment
    JONATHAN QUINCY BROWN; Fiscal Year: 2012
  9. TAS::75 0849::TAS SBIR TOPIC 307 PHASE I NOVEL IMAGING AGENTS TO EXPAND THE CLIN
    BRYAN WALSER; Fiscal Year: 2011
  10. Influence of Exercise and Adiposity on Biomarkers of Breast Cancer Recurrence
    Lisa J Wood; Fiscal Year: 2013

Detail Information

Publications310 found, 100 shown here

  1. pmc Deleterious mutations in the Zinc-Finger 469 gene cause brittle cornea syndrome
    Almogit Abu
    Danek Gertner Institute of Human Genetics, Sheba Medical Center, Tel Hashomer 52621, Israel
    Am J Hum Genet 82:1217-22. 2008
    ..We have identified two frameshift mutations in the Zinc-Finger 469 gene (ZNF469)...
  2. doi Brittle cornea syndrome associated with a missense mutation in the zinc-finger 469 gene
    Anne E Christensen
    Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway
    Invest Ophthalmol Vis Sci 51:47-52. 2010
    To investigate the diverse clinical manifestations, identify the causative mutation and explain the association with red hair in a family with brittle cornea syndrome (BCS).
  3. pmc Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness
    Yi Lu
    Genetics and Population Health, Queensland Institute of Medical Research, Brisbane, Australia
    PLoS Genet 6:e1000947. 2010
    ..95x10(-11). The nearest gene to the associated chromosome 16 SNPs was ZNF469, a locus recently implicated in Brittle Cornea Syndrome (BCS), a very rare disorder characterized by abnormal thin ..
  4. doi New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8
    Veronique Vitart
    MRC Human Genetics Unit, IGMM, Edinburgh, UK
    Hum Mol Genet 19:4304-11. 2010
    ..22 SD, P = 7.1 × 10(-8)) for which the closest candidate genes (although ≥90 kb away) were zinc finger 469 (ZNF469) on 16q24.2 and collagen 5 alpha 1 (COL5A1) on 9q34.2, respectively...
  5. pmc Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance
    Emma M M Burkitt Wright
    Genetic Medicine Research Group, Manchester Biomedical Research Centre, Manchester Academic Health Sciences Centre, University of Manchester and Central Manchester Foundation Trust, St Mary s Hospital, Manchester M13 9WL, UK
    Am J Hum Genet 88:767-77. 2011
    ..b>ZNF469, encoding a zinc finger protein of hitherto undefined function, has been identified as a quantitative trait locus ..
  6. doi Population-based meta-analysis in Caucasians confirms association with COL5A1 and ZNF469 but not COL8A2 with central corneal thickness
    Rene Hoehn
    Department of Ophthalmology, University Medical Center Mainz, Langenbeckstr 1, 55131 Mainz, Germany
    Hum Genet 131:1783-93. 2012
    ..On chromosome 16q24, the locus is located in an intergenic region near the ZNF469 gene (top SNP: rs9938149, P = 1.45 × 10(-12))...
  7. doi Identification of a novel ZNF469 mutation in a large family with Ehlers-Danlos phenotype
    Mohammed Al-Owain
    Department of Medical Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Gene 511:447-50. 2012
    ..BCS-1 and BCS-2 are caused by recessive mutations in ZNF469 and PRDM5, respectively. Both genes play a role in the regulatory pathway of corneal development and maintenance...
  8. pmc Breast cancer outcomes among older women: HMO, fee-for-service, and delivery system comparisons
    A Lee-Feldstein
    Center for Health Policy and Research, Department of Medicine, College of Medicine, University of California, Irvine, Calif 92697-5800, USA
    J Gen Intern Med 16:189-99. 2001
    ..50; 95% CI, 0.31 to 0.82). Use of breast-conserving surgery plus radiation (BCS+) varied significantly by hospital type (including HMO-owned and various-sized community hospitals) and time...
  9. pmc Copper chelation-induced reduction of the biological activity of S-nitrosothiols
    M P Gordge
    Institute of Urology, University College London
    Br J Pharmacol 114:1083-9. 1995
    ..and S-nitrosoglutathione (GSNO) was investigated, using the specific copper chelator bathocuproine sulphonate (BCS), and human washed platelets as target cells. 2...
  10. ncbi [Clinical manifestation and patho-typing of biliary cast syndrome in patients after orthotopic liver transplantation]
    Xiao Dan Zhu
    Institute of Liver Transplantation, General Hospital of Chinese Armed Police Forces, Beijing 100039, China
    Zhonghua Wai Ke Za Zhi 46:728-32. 2008
    To summarize the Patho-typing and the clinical manifestation of biliary cast syndrome (BCS) in patients after orthotopic liver transplantation.
  11. ncbi 172 reuse of autoclaved intravaginal progesterone device to estrous synchronization in toggenburg goats in the breeding season
    J M G Souza
    Federal University of Vicosa, Vicosa, MG, Brazil
    Reprod Fertil Dev 23:188. 2011
    ..9±9.8kg and 3.4±0.3) goats were assigned according to weight and body condition score (BCS, 1 to 5 scale) into 3 treatments. Animals received new devices (n=25; 48.2±11.5kg and BCS 3.4±0.3) containing 0...
  12. ncbi Local treatment of hemorrhoidal disease and perianal eczema. Meta-analysis of the efficacy and safety of an Escherichia coli culture suspension alone or in combination with hydrocortisone
    Volker Wienert
    University Hospital, Aachen, Germany
    Arzneimittelforschung 52:515-23. 2002
    ..available clinical data on the efficacy and safety of ointments containing either a bacterial culture suspension (BCS) from Escherichia coli or a combination of BCS with hydrocortisone (CAS 50-23-7) (BCS: Posterisan, and BCS + HC: ..
  13. ncbi Radical surgery for Budd-Chiari syndrome through exposure of the entire inferior vena cava of the hepatic segment
    Xiao Ming Zhang
    Department of Vascular Surgery, Peking University People s Hospital, Beijing, China
    Chin Med J (Engl) 120:626-9. 2007
    Several kinds of radical surgery for the treatment of Budd-Chiari syndrome (BCS) have been devised...
  14. ncbi Interaction of calf suckling, use of oxytocin and milk yield with reproductive performance of dairy buffaloes
    Muhammad Subhan Qureshi
    Faculty of Animal Husbandry and Veterinary Science, NWFP Agricultural University, Peshawar 25120, Pakistan
    Anim Reprod Sci 106:380-92. 2008
    ..Data on milk yield, body condition score (BCS) and reproductive parameters were recorded weekly...
  15. ncbi Influence of body condition score on by-product yield and value from cull beef cows
    J K Apple
    Department of Animal Science, University of Arkansas, Fayetteville 72701, USA
    J Anim Sci 77:2670-9. 1999
    ..representing British and Continental phenotypes were slaughtered to measure the influence of body condition score (BCS) on by-product yield and value...
  16. pmc A 27-year experience with surgical treatment of Budd-Chiari syndrome
    M J Orloff
    Department of Surgery, University of California San Diego Medical Center, San Diego, California 92103 8999, USA
    Ann Surg 232:340-52. 2000
    To determine the effects of surgical portal decompression in Budd-Chiari syndrome (BCS) on survival, quality of life, shunt patency, liver function, portal hemodynamics, and hepatic morphology during periods ranging from 3.5 to 27 years.
  17. ncbi Patterns of care analysis among women with ductal carcinoma in situ in North Carolina
    LeRon C Jackson
    Department of Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Am J Surg 195:164-9. 2008
    ..Further study goals included the identification of predictors of breast-conserving surgery (BCS), adjuvant radiation, and/or hormonal therapy, as well as breast reconstruction after mastectomy.
  18. pmc Radiological and pathological size estimations of pure ductal carcinoma in situ of the breast, specimen handling and the influence on the success of breast conservation surgery: a review of 2564 cases from the Sloane Project
    J Thomas
    Pathology Department, Western General Hospital and Breakthrough Breast Cancer Research Unit, Edinburgh EH4 2XU, UK
    Br J Cancer 102:285-93. 2010
    ..We have correlated these sizes with histological grade, specimen-handling methods, particularly the use of specimen slice radiographs, and the success or failure of breast-conserving surgery (BCS).
  19. ncbi Copper redox-dependent activation of 2-tert-butyl(1,4)hydroquinone: formation of reactive oxygen species and induction of oxidative DNA damage in isolated DNA and cultured rat hepatocytes
    Yunbo Li
    Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St Albert Hall, St John s University, Jamaica, NY 11439, USA
    Mutat Res 518:123-33. 2002
    ..of O(2) and the generation of H(2)O(2) and TBQ could be completely blocked by bathocuproinedisulfonic acid (BCS) and reduced glutathione (GSH), two Cu(I)-chelators...
  20. doi Analysis of heterocyclic amines and beta-carbolines by liquid chromatography-mass spectrometry in cooked meats commonly consumed in Korea
    Y M Back
    Department of Food Science and Technology, Dongguk University, Seoul 100 715, South Korea
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 26:298-305. 2009
    ..In this study, 13 HAs and 2 beta-carbolines (BCs) were analyzed in cooked Korean meat products, including griddled bacon, griddled pork loin, boiled pork loin, ..
  21. ncbi [Budd-Chiari syndrome and TIPS--twelve years' experience]
    V Safka
    Ustav fyziologie LF UK, Hradec Kralove
    Cas Lek Cesk 144:38-42. 2005
    Massive thrombosis of hepatic veins is clinically the most serious type of Budd-Chiari syndrome (BCS). Ischemic impairment is the basic problem in case of acute or fulminate course of BCS...
  22. ncbi Effects of postpartum dietary fat and body condition score at parturition on plasma, adipose tissue, and milk fatty acid composition of lactating beef cows
    S L Lake
    Department of Animal Science, University of Wyoming, Laramie, WY 82071 3684, USA
    J Anim Sci 85:717-30. 2007
    ..conducted with lactating Angus x Gelbvieh beef cows to determine the effects of postpartum lipid supplementation, BCS at parturition, and day of lactation on fatty acid profiles in plasma, adipose tissue, and milk. In Exp...
  23. doi Body condition change ante- and postpartum, health and reproductive performance in German Holstein cows
    M Hoedemaker
    Production Medicine Unit, Clinic for Cattle, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, Hannover, Germany
    Reprod Domest Anim 44:167-73. 2009
    The effects of body condition score (BCS) change and status ante- and postpartum (pp) on health and reproductive performance in 234 German Holstein cows from eight dairy farms were evaluated...
  24. ncbi Secretion of IGF-1 by ovine granulosa cells: effects of growth hormone and follicle stimulating hormone
    M Khalid
    Department of Farm Animal and Equine Medicine, The Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Harfield, Hertfordshire AL9 7TA, UK
    Anim Reprod Sci 58:261-72. 2000
    ..In the first set of experiments, cells were incubated in the presence of bovine calf serum (BCS) (2.5%) for the initial 48 h of culture...
  25. doi Genetic relationships between body condition score and reproduction traits in Canadian Holstein and Ayrshire first-parity cows
    C Bastin
    University of Liege, Gembloux Agro Bio Tech, Animal Science Unit, B 5030 Gembloux, Belgium
    J Dairy Sci 93:2215-28. 2010
    The objective of this study was to investigate the genetic relationship between body condition score (BCS) and reproduction traits for first-parity Canadian Ayrshire and Holstein cows...
  26. ncbi Histopathologic classification of breast cancer in Sweden and Italy: a comparison between two pathologists
    D Palli
    Epidemiology Unit, Florence, Italy
    Tumori 78:247-9. 1992
    ..Overall, comparison of diagnoses of 372 BCs according to a simplified WHO histologic classification system (in four combined categories) revealed agreement for ..
  27. ncbi Physicochemical profiling (solubility, permeability and charge state)
    A Avdeef
    pION INC, Woburn, MA 01801, USA
    Curr Top Med Chem 1:277-351. 2001
    ..Poor solubility and poor permeability account for many PK failures. FDA's Biopharmaceutics Classification System (BCS) is an attempt to rationalize the critical components related to oral absorption...
  28. ncbi [Local relapse in young (< or = 40 years) women with breast cancer after mastectomy or breast conserving surgery: 15-year results]
    Janos Fodor
    Országos Onkológiai Intézet, 1122 Budapest, Ráth Gyorgy
    Magy Onkol 49:203, 205-8. 2005
    Data from various sources indicate that after breast conserving surgery (BCS), younger patients have a high risk of local relapse, but there is insufficient evidence about the risk of post-mastectomy local recurrence...
  29. doi Effects of plane of nutrition and selenium supply during gestation on ewe and neonatal offspring performance, body composition, and serum selenium
    A M Meyer
    Department of Animal Sciences, North Dakota State University, Center for Nutrition and Pregnancy, Fargo 58108, USA
    J Anim Sci 88:1786-800. 2010
    ..From d 95 of gestation through parturition and d 20 of lactation, ewe BW and BCS were least (P <or= 0...
  30. doi The use of drug metabolism for prediction of intestinal permeability (dagger)
    Mei Ling Chen
    Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20993, USA
    Mol Pharm 6:74-81. 2009
    The Biopharmaceutics Classification System (BCS), based on the aqueous solubility and intestinal permeability of a drug substance, has been widely used to predict the extent of drug absorption during the course of pharmaceutical ..
  31. ncbi Access to multidisciplinary cancer care: is it linked to the use of breast-conserving surgery with radiation for early-stage breast carcinoma?
    Laura Mae Baldwin
    Department of Family Medicine, University of Washington, Seattle, Washington 98195 4696, USA
    Cancer 100:701-9. 2004
    Breast-conserving surgery (BCS) with radiation (BCSR) requires a multidisciplinary care approach between surgeons and radiation oncologists.
  32. ncbi A first look at variations in use of breast conserving surgery at five teaching hospitals in Japan
    Tatsuro Ishizaki
    Department of Healthcare Economics and Quality Management, School of Public Health, Kyoto University Graduate School of Medicine, Japan
    Int J Qual Health Care 14:411-8. 2002
    We assessed variations in the use of breast conserving surgery (BCS) for operable breast cancer paticnts among hospitals in Japan, and then compared the length of stay (LOS) and total charges during hospitalization between patients who ..
  33. pmc Understanding the breast cancer experience of women: a qualitative study of African American, Asian American, Latina and Caucasian cancer survivors
    Kimlin Tam Ashing-Giwa
    Department of Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA, USA
    Psychooncology 13:408-28. 2004
    ..We conducted a qualitative study with breast cancer survivors (BCS) of various ethnicities...
  34. ncbi Haemolytic activities and adjuvant effect of Bupleurum chinense saponins on the immune responses to ovalbumin in mice
    Hong Xiang Sun
    College of Animal Sciences, Zhejiang University, Kaixuan Road 268, Hangzhou, Zhejiang 310029, China
    Vaccine 24:1324-31. 2006
    In this study, the haemolytic activities of Bupleurum chinense saponins (BCS) and its adjuvant potentials on the immune responses of ICR mice against ovalbumin (OVA) were evaluated...
  35. doi Modified transjugular intrahepatic portosystemic shunt in the treatment of Budd-Chiari syndrome
    X Wu
    Research Institute of General Surgery, School of Medicine, Nanjing University, Jinling Hospital, Nanjing, Jiangsu Province, China
    Int J Clin Pract 64:460-4. 2010
    The aim of this study was to determine the outcome of a modified transjugular intrahepatic portosystemic shunt (MTIPS) in the treatment of the Budd-Chiari syndrome (BCS, occlusion of the hepatic veins).
  36. doi Breast-conserving surgery using projection and reproduction techniques of surgical-position breast MRI in patients with ductal carcinoma in situ of the breast
    Masahiro Sakakibara
    Department of General Surgery, Chiba University Graduate School of Medicine, Chuoku, Chiba, Japan
    J Am Coll Surg 207:62-8. 2008
    In this study, we report a breast-conserving surgery (BCS) approach that uses projection and reproduction techniques of breast MRI obtained in the surgical position to the breast surface in patients with ductal carcinoma in situ (DCIS) ..
  37. doi High levels of soluble Major Histocompatibility Complex class I related chain A (MICA) are associated with biliary cast syndrome after liver transplantation
    Yizhou Zou
    Department of Immunology, Xiang Ya School of Medicine, Central South University, Hunan, China
    Transpl Immunol 21:210-4. 2009
    The biliary cast syndrome (BCS) is a frequent problem following liver transplantation. The pathogenesis of this complication is not well understood...
  38. doi Prepartum dietary management of energy intake affects postpartum intake and lactation performance by primiparous and multiparous Holstein cows
    N A Janovick
    Department of Animal Sciences, University of Illinois, Urbana, IL, USA
    J Dairy Sci 93:3086-102. 2010
    ..and primiparous cows assigned to OVR gained body condition during the dry period [initial body condition score (BCS)=3.3], but were not overconditioned by parturition (BCS=3.5)...
  39. doi Glutamate supply positively affects serum release of triiodothyronine and insulin across time without increases of glucose during the onset of puberty in female goats
    C A Meza-Herrera
    Universidad Autónoma Chapingo Unidad Regional Universitaria de Zonas Áridas A P No 8, Bermejillo, Durango 35230, Mexico
    Anim Reprod Sci 125:74-80. 2011
    ..52±1.04 kg LW, 3.4±0.12 body condition score [BCS], receiving an intravenous infusion of 7 mg kg(-1) live weight [LW] of l-glutamate, twice a week, and (ii) control ..
  40. ncbi The suitability of an in situ perfusion model for permeability determinations: utility for BCS class I biowaiver requests
    Jae Seung Kim
    TSRL, Inc, Ann Arbor, Michigan 48108, USA
    Mol Pharm 3:686-94. 2006
    ..studies for immediate release (IR) solid oral dosage forms based on the Biopharmaceutics Classification System (BCS)...
  41. doi The effects of metabolizable energy intake on body fat depots of adult Pelibuey ewes fed roughage diets under tropical conditions
    A J Chay-Canul
    Facultad de Medicina Veterinaria y Zootecnia, Universidad Autonoma de Yucatan, Carr Mérida Xmatkuil km 15 5, Merida, Yucatan, Mexico
    Trop Anim Health Prod 43:929-36. 2011
    ..Eighteen 3-year-old Pelibuey ewes with similar body weight (BW) of 37.6 ± 4.0 kg and body condition score (BCS) of 2.5 ± 0.20 were randomly assigned to three groups of six ewes each in a completely randomized design...
  42. ncbi Stage at diagnosis and treatment patterns among older women with breast cancer: an HMO and fee-for-service comparison
    G F Riley
    Health Care Financing Administration, Baltimore, MD 21244, USA
    JAMA 281:720-6. 1999
    ..Few studies have compared patterns of care in health maintenance organization (HMO) and fee-for-service (FFS) settings...
  43. doi Biopharmaceutics classification system: validation and learnings of an in vitro permeability assay
    Victoria E Thiel-Demby
    GlaxoSmithKline, Research Triangle Park, North Carolina, USA
    Mol Pharm 6:11-8. 2009
    The Biopharmaceutics Classification System (BCS) is the scientific basis for classifying drugs based on their aqueous solubility and intestinal permeability that supports in vivo bioavailability and bioequivalence waivers for immediate-..
  44. doi Feasibility and midterm outcomes of percutaneous transhepatic balloon angioplasty for symptomatic Budd-Chiari syndrome secondary to hepatic venous obstruction
    Tianxiao Li
    Department of Interventional Radiology, People s Hospital of Henan Province, Zhengzhou, Henan, Peoples Republic of China
    J Vasc Surg 50:1079-84. 2009
    This study evaluated the feasibility and outcomes of percutaneous transhepatic balloon angioplasty (PTBA) of the hepatic vein in the management of Budd-Chiari syndrome (BCS) secondary to hepatic venous outflow obstruction.
  45. ncbi Storage time and eggshell colour of pheasant eggs vs. the number of blastodermal cells and hatchability results
    Radosław Kozuszek
    Department of Poultry Science, Poznan University of Life Sciences, Witosa 45, 61 693 Poznań, Poland
    Folia Biol (Krakow) 57:121-30. 2009
    ..dark-brown and olive eggs were characterised by a similar and significantly higher (by about 48%) number of embryo BCs in comparison with light-brown and blue eggs...
  46. doi Effect of weaning date (normal vs. late) on performance of young and mature beef cows and their progeny in a fall calving system in the Southern Great Plains
    M D Hudson
    Department of Animal Science, Oklahoma State University, Stillwater, USA
    J Anim Sci 88:1577-87. 2010
    ..Mature cows were heavier (P < 0.01) than young cows throughout the trial, although BCS was similar (P >or= 0.10) among cow age classes. Cow BW (P = 0.58) and BCS (P = 0...
  47. pmc Patterns of initial management of node-negative breast cancer in two Canadian provinces. British Columbia/Ontario Working Group
    V Goel
    Department of Preventive Medicine and Biostatistics, University of Toronto
    CMAJ 156:25-35. 1997
    ..To describe the patterns of initial management of node-negative breast cancer in Ontario and British Columbia and to compare the characteristics of the patients and tumours and of the physicians and hospitals involved in management...
  48. ncbi Effects of body condition score and score change on the reproductive performance of dairy cows: a meta-analysis
    F Lopez-Gatius
    Department of Animal Production, University of Lleida, Escuela Técnica Superior de Ingeniería Agraria, Avda Alcalde Rovira Roure 177, 25198 Lleida, Spain
    Theriogenology 59:801-12. 2003
    A meta-analysis was conducted to evaluate the effects of body condition score (BCS) at parturition and at first AI, and of body condition change during the early lactation period on the variables pregnancy rate at first AI and number of ..
  49. ncbi Milk production of dairy cows fed wet corn gluten feed during the dry period and lactation
    P J Kononoff
    Department of Animal Science, University of Nebraska, Lincoln 68583 0908, USA
    J Dairy Sci 89:2608-17. 2006
    ..of feeding wet corn gluten feed (WCGF) on 305-d milk production, dry matter (DM) intake, body condition score (BCS), and health...
  50. ncbi Genetics of body condition score in New Zealand dairy cows
    J E Pryce
    Livestock Improvement Corporation Ltd, Private Bag 3016, Hamilton, New Zealand
    J Dairy Sci 89:4424-32. 2006
    Body condition score (BCS) data were collected on 169,661 first-parity cows from herds participating in progeny testing schemes and linear type assessment...
  51. ncbi Relationships among inflammatory cytokines, obesity, and insulin sensitivity in the horse
    M M Vick
    Department of Veterinary Science, Maxwell Gluck Equine Research Center, University of Kentucky, Lexington 40546, USA
    J Anim Sci 85:1144-55. 2007
    ..Age was recorded and BCS and percent body fat (% FAT) were determined as measures of obesity in 60 mares...
  52. doi Effects of late gestation supplementation of rumen undegradable protein, vitamin E, zinc, and chlortetracycline to ewes on indices of immune transfer and productivity
    R R Redden
    Department of Animal and Range Sciences, Montana State University, Bozeman 59717, USA
    J Anim Sci 88:1125-34. 2010
    ..Ewes of different age (Exp. 1; 3- vs. 6-yr-old; n = 52) and BCS (Exp. 2; good vs. poor BCS; 3.0 and 1.7 +/- 0...
  53. ncbi Preliminary evaluation of magnetic resonance fresh blood imaging for diagnosis of Budd-Chiari syndrome
    Ke Ren
    Department of Radiology, First Affiliated Hospital of China Medical University, Shenyang 110001, China
    Chin Med J (Engl) 120:95-9. 2007
    Budd-Chiari syndrome (BCS) is a rare disease with portal hypertension caused by the blockage of the hepatic vein and/or the inferior vena cava (IVC)...
  54. doi Associations among patterns in daily body weight, body condition scoring, and reproductive performance in high-producing dairy cows
    M van Straten
    Hachaklait, Mutual Society for Veterinary Services, Caesarea Industrial Park, Israel
    J Dairy Sci 92:4375-85. 2009
    The objective was to investigate the associations between body condition scores (BCS) and daily body weight (BW) in the first 150 d of lactation (DIM) and reproductive performance in high-producing dairy cows...
  55. doi Effects of acclimation to human interaction on performance, temperament, physiological responses, and pregnancy rates of Brahman-crossbred cows
    R F Cooke
    Oregon State University, Eastern Oregon Agricultural Research Center, Burns 97720, USA
    J Anim Sci 87:4125-32. 2009
    ..Approximately 45 d after weaning (August 2006) in yr 1, cows were evaluated for BW, BCS, and temperament (chute score, pen score, and exit velocity), stratified by these measurements in addition to breed ..
  56. doi Heritability of gross feed efficiency and associations with yield, intake, residual intake, body weight, and body condition score in 11 commercial Pennsylvania tie stalls
    J E Vallimont
    Department of Dairy and Animal Science, The Pennsylvania State University, University Park, PA 16802, USA
    J Dairy Sci 94:2108-13. 2011
    ..by regressing daily DMI on daily milk, fat, and protein yields, body weight (BW), daily body condition score (BCS) gain or loss, the interaction between BW and BCS gain or loss, and days in milk (DIM)...
  57. doi Effects of nutritional support on hospital outcome in dogs and cats
    Marcio A Brunetto
    Department of Veterinary Clinic and Surgery, Sao Paulo State University UNESP, Jaboticabal, SP, Brazil
    J Vet Emerg Crit Care (San Antonio) 20:224-31. 2010
    ..the effects of assisted nutritional support on hospital outcome in dogs and cats, and the relationship between hospital outcome and energy intake, body condition score (BCS), physical status score, and type of nutritional support used.
  58. ncbi Transjugular intrahepatic portosystemic shunt creation in Budd-Chiari syndrome: percutaneous ultrasound-guided direct simultaneous puncture of the portal vein and vena cava
    Fatih Boyvat
    Department of Radiology, Baskent University, Faculty of Medicine, Fevzi Cakmak Cad 10 sok No 45, 06490, Bahcelievler, Ankara, Turkey
    Cardiovasc Intervent Radiol 29:857-61. 2006
    Budd-Chiari syndrome (BCS) is an uncommon disorder that can be life-threatening, depending on the degree of hepatic venous outflow obstruction...
  59. ncbi Survival disadvantage among Medicaid-insured breast cancer patients treated with breast conserving surgery without radiation therapy
    Kristie Long Foley
    Division of Public Health Sciences, Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Breast Cancer Res Treat 101:207-14. 2007
    Clinical studies indicate that breast cancer patients treated with breast conserving surgery (BCS) without radiotherapy (RT) have a greater risk of recurrence and mortality compared to those receiving BCS plus RT...
  60. pmc The Indiana University telephone-based assessment of neuropsychological status: a new method for large scale neuropsychological assessment
    Frederick W Unverzagt
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Int Neuropsychol Soc 13:799-806. 2007
    ..to a telephone administration format for use in a large survey of quality of life in breast cancer survivors (BCS)...
  61. doi Eighteen years of liver transplantation experience in patients with advanced Budd-Chiari syndrome
    Frank Ulrich
    Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Clinical Centre, Berlin, Germany
    Liver Transpl 14:144-50. 2008
    The long-term results of liver transplantation for Budd-Chiari syndrome (BCS) and timely indication for the procedure are still under debate...
  62. doi Productive and reproductive performance of strategically supplemented free grazing prepartum Bunaji cows in the agropastoral farming system
    O A Olafadehan
    Department of Animal Production Technology, Federal College of Wildlife Management, P M B 268, New Bussa, Niger State, Nigeria
    Trop Anim Health Prod 41:1275-81. 2009
    ..The average daily gains (ADG) and body condition scores (BCS) of supplemented cows were significantly better than the non-supplemented cows...
  63. pmc Use of a body condition score technique to assess health status in a rat model of polycystic kidney disease
    Debra L Hickman
    Research and Development Service, VA Medical Center, Portland, OR, USA
    J Am Assoc Lab Anim Sci 49:155-9. 2010
    ..Body condition score (BCS) techniques have been described for a variety of species, including mice...
  64. doi Resistance and resilience of traditionally managed West African Dwarf goats from the savanna zone of northern Nigeria to naturally acquired trypanosome and gastrointestinal nematode infections
    J M Behnke
    School of Biology, University of Nottingham, University Park, Nottingham NG72RD, UK
    J Helminthol 85:80-91. 2011
    ..Body condition scores (BCS) also declined with month of the study, but there was a marked difference between the two sexes, with male animals ..
  65. doi Storage of Buffy-coat-derived platelets in additive solutions: in vitro effects on platelets prepared by the novel TACSI system and stored in plastic containers with different gas permeability
    P Sandgren
    Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, Sweden
    Vox Sang 99:341-7. 2010
    The novel TACSI system is designed for automated preparation of platelets (PLTs) from pooled buffy coats (BCs). One TACSI device will handle 6 units at the same time...
  66. pmc Development, optimization, and characterization of solid self-nanoemulsifying drug delivery systems of valsartan using porous carriers
    Sarwar Beg
    Department of Pharmaceutics, Roland Institute of Pharmaceutical Sciences, Khodasingi, Berhampur, 760 010, Odisha, India
    AAPS PharmSciTech 13:1416-27. 2012
    ..Thus, the present studies demonstrated the bioavailability enhancement potential of porous carriers based S-SNEDDS for a BCS class II drug, valsartan.
  67. doi In vitro behaviors of rat mesenchymal stem cells on bacterial celluloses with different moduli
    Siriporn Taokaew
    Department of Chemical Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand Department of Chemical and Biomolecular Engineering, The University of Akron, Akron, OH 44325 3906, United States
    Mater Sci Eng C Mater Biol Appl 38:263-71. 2014
    ..Freeze dried BCs had loose cross-sectional structures and a thickness of ~4...
  68. doi Utilization and impact of a postmastectomy radiation boost for invasive breast cancer
    Jyoti Mayadev
    Department of Radiation Oncology, University of California Davis Medical Center, Sacramento, California Electronic address
    Pract Radiat Oncol 4:e269-78. 2014
    Additional radiation following postmastectomy radiation (PMRT) has an undefined benefit. We investigate those likely to be selected for a chest wall boost (CWB) and its effect on breast cancer survival (BCS) and overall survival (OS).
  69. doi Structure and functioning of a multidisciplinary 'Heart Team' for patients with coronary artery disease: rationale and recommendations from a joint BCS/BCIS/SCTS working group
    Heyman Luckraz
    Heart and Lung Centre, Wolverhampton, UK
    Eur J Cardiothorac Surg 48:524-9. 2015
    ..This work was carried out on behalf of The British Cardiovascular Society (BCS), Society for Cardiothoracic Surgery in Great Britain and Ireland (SCTS) and British Cardiovascular Intervention ..
  70. doi Development of self emulsifying lipid formulations of BCS class II drugs with low to medium lipophilicity
    Vincent Jannin
    Gattefossé SAS, 36 chemin de Genas 69804 Saint Priest, France Electronic address
    Int J Pharm 495:385-92. 2015
    ..All model drugs tested (piroxicam, curcumin and nifedipine) belong to the same chemical space--small BCS class II molecules with logP ranging from 2 to 3...
  71. pmc Comparative effectiveness study of breast-conserving surgery and mastectomy in the general population: A NCDB analysis
    Kai Chen
    Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat Sen Memorial Hospital, Sun Yat Sen University, Guangzhou, China
    Oncotarget 6:40127-40. 2015
    Recent studies have revealed that breast-conserving surgery (BCS) with radiotherapy (RT) led to better survival than mastectomy in some populations...
  72. doi Positive margins prediction in breast cancer conservative surgery: Assessment of a preoperative web-based nomogram
    Lídia Alves-Ribeiro
    Medical Faculty of Porto University, Alameda Prof Hernani Monteiro, Porto 4200 319, Portugal Electronic address
    Breast 28:167-73. 2016
    ..to diminish reoperation rates and reduce the probability of local recurrence in breast conservative surgery (BCS). This study aims to validate the Dutch BreastConservation! nomogram, created by Pleijhus et al...
  73. ncbi Biowaiver Eligibility of a Lower Strength Ramipril/Hydrochlorothiazide Immediate Release Tablets Using a New Validated HPLC Analytical Method
    A N Zaid
    Department of Pharmacy, Faculty of Medicine and Health Sciences, An Najah National University, Nablus, Palestine
    Drug Res (Stuttg) 66:539-546. 2016
    ..Accordingly, an alternative in vitro study (biowaivers) has been introduced for drugs which belong to BCS class I and III and for other strengths of already approved higher drug strength...
  74. ncbi Effects of resistance exercise in women with or at risk for breast cancer-related lymphedema
    Emily Simonavice
    School of Health and Human Performance, Georgia College and State University, Campus Box 112, Milledgeville, GA, 31061, USA
    Support Care Cancer 25:9-15. 2017
    Breast cancer survivors (BCS) have been told in the past to avoid strenuous repetitive activities in order to decrease the risk of lymphedema development...
  75. pmc Hepatic Encephalopathy in Connection With Budd-Chiari Syndrome due to Infection With Echinococcus Multilocularis: A Case Report
    Ahmet Cumhur Dulger
    Department of Gastroenterology, Medical Faculty, Yuzuncu Yil University, Van, Turkey
    Gastroenterology Res 4:127-130. 2011
    Budd-Chiari syndrome (BCS) is a hepatic venous outflow block generally resulting from disorders affecting hepatic venous system. Elevated hepatic venous pressure results in portal hypertension. BCS may also cause hepatic encephalopathy...
  76. doi Pectinate ligament dysplasia in the Border Collie, Hungarian Vizsla and Golden Retriever
    James A C Oliver
    Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK
    Vet Rec . 2016
    ..Gonioscopy was performed in 102 BCs, 112 HVs and 230 GRs and the percentage of iridocorneal angle affected by PLD was estimated and classified as ..
  77. ncbi Differential reinnervation of retinal bipolar cell dendrites and axon terminals by dopamine interplexiform cells following dopamine depletion with 6-OHDA
    S Yazulla
    Department of Neurobiology and Behavior, State University of New York at Stony Brook, New York 11794 5230, USA
    J Comp Neurol 382:535-45. 1997
    ..were double labeled for protein kinase C and tyrosine hydroxylase (TH) immunocytochemistry to identify the ON-BCs and the DA-IPCs, respectively...
  78. ncbi The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow
    Malene Digmann Bjerregaard
    Department of Hematology, Rigshospitalet, University of Copenhagen, Denmark
    Blood 101:4322-32. 2003
    ..PMs]); intermediate mature (myelocytes [MCs] and metamyelocytes [MMs]); and mature neutrophil cells (band cells [BCs] and segmented neutrophil cells [SCs])...
  79. ncbi Budd-Chiari syndrome: in evolution
    Vladimir Bogin
    Internal Medicine, Longview, WA, USA
    Eur J Gastroenterol Hepatol 17:33-5. 2005
    Budd-Chiari syndrome (BCS) is a rare but potentially life-threatening disorder caused by hepatic venous obstruction, distinct from cardiac causes of hepatic congestion or sinusoidal obstruction syndrome (formerly known as veno-occlusive ..
  80. ncbi Direct intrahepatic cavo-portal shunts in Budd-Chiari syndrome: Role of simultaneous fluoroscopy and trans-abdominal ultrasonography
    Shyamkumar N Keshava
    Department of Radiology, Christian Medical College and Hospital, Vellore 632 004, India
    Indian J Gastroenterol 25:248-50. 2006
    Transjugular intrahepatic porto-systemic shunt (TIPS) for Budd-Chiari syndrome (BCS) can be inserted from inferior vena cava or hepatic vein to portal vein...
  81. ncbi Cobalamin, folate and inorganic phosphate abnormalities in ill cats
    Nicola Reed
    Division of Veterinary Clinical Studies, Royal Dick School of Veterinary Studies, University of Edinburgh Hospital for Small Animals, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK
    J Feline Med Surg 9:278-88. 2007
    ..and pancreas) and to ascertain whether severity of disease (as assessed by bodyweight and body condition score (BCS)) related to degree of deficiency. The study population comprised 103 cats, of which 16...
  82. doi Conjugated linoleic acid content in adipose tissue of calves suckling beef cows on pasture and supplemented with raw or extruded soybeans
    C Paradis
    Departement des Sciences Animales, Universite Laval, Quebec, Quebec, Canada
    J Anim Sci 86:1624-36. 2008
    ..c. adipose tissue of suckling calves. Thirty-two spring-calving cows (BW 624 +/- 76 kg; BCS 3.5 +/- 0.4; mean +/- SD) and calves (BW 127 +/- 15 kg) were separated into 2 groups...
  83. doi Comparison of photon with electron boost in treatment of early stage breast cancer
    Arpad Kovacs
    Health Science Center, University of Kaposvar, Kaposvar, Hungary
    Pathol Oncol Res 14:193-7. 2008
    In the treatment of early stage breast cancer breast conserving surgery (BCS) followed by whole breast irradiation (WBI) is a standard method...
  84. ncbi [Mesoatrial shunt in Budd-Chiari syndrome]
    Darko Mirkovic
    Klinika za abdominalnu i endokrinu hirurgiju, Beograd, Srbija
    Vojnosanit Pregl 66:69-73. 2009
    Budd-Chiari syndrome (BCS) represents partial or total occlusion of the hepatic veins with or without simultaneous obstruction of vena cava inferior (VCI)...
  85. ncbi Balò's concentric sclerosis presenting with benign clinical course and multiple sclerosis-like lesions on magnetic resonance images
    Yongmei Li
    Department of Neurology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China
    Neurol India 57:66-8. 2009
    Balò's concentric sclerosis (BCS) is a rare primary demyelinating disease of central nervous system (CNS) and is considered to be a variant of multiple sclerosis (MS)...
  86. doi A decade of land use contributes to changes in the chemistry, biochemistry and bacterial community structures of soils in the Cerrado
    R S Peixoto
    LEMM Laboratório de Ecologia Microbiana Molecular, Instituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Antonie Van Leeuwenhoek 98:403-13. 2010
    ..Soil chemical analysis, microbial biomass and the enzyme activities were also evaluated and correlated with the BCS measurements...
  87. pmc Timing of radiotherapy and outcome in patients receiving adjuvant endocrine therapy
    Per Karlsson
    Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden
    Int J Radiat Oncol Biol Phys 80:398-402. 2011
    To evaluate the association between the interval from breast-conserving surgery (BCS) to radiotherapy (RT) and the clinical outcome among patients treated with adjuvant endocrine therapy.
  88. doi Relationship of ruminal temperature with parturition and estrus of beef cows
    M J Cooper-Prado
    Department of Animal Science, Oklahoma Agricultural Experiment Station, Oklahoma State University, Stillwater 74078 0425, USA
    J Anim Sci 89:1020-7. 2011
    ..0 ± 0.2 mo of gestation. Boluses were programmed to transmit RuT every 15 min. Cows (BW = 623 ± 44 kg, BCS = 4.9 ± 0.4) calved during 3 wk, and estrus was synchronized at 77 ± 7 d after calving with PGF(2α)...
  89. ncbi Results of liver transplantation in the treatment of Budd-Chiari syndrome
    Anna Mackiewicz
    Students Scientific Group of Department of General, Transplantation and Liver Surgery, Medical University of Warsaw, Warsaw, Poland
    Ann Transplant 17:5-10. 2012
    Budd-Chiari syndrome (BCS) is a rare disorder which can lead to liver failure. It arises from an occlusion of small vessels and/or thrombosis of the major hepatic veins...
  90. doi Application of a ternary HP-β-CD-complex approach to improve the dissolution performance of a poorly soluble weak acid under biorelevant conditions
    Thomas Zoeller
    Johann Wolfgang Goethe University, Institute of Pharmaceutical Technology, 9 Max von Laue Street, Frankfurt am Main 60438, Germany
    Int J Pharm 430:176-83. 2012
    ..This formulation approach, particularly with the new polymer, appears to be promising in terms of enhancing the bioavailability of BCS class II drugs.
  91. ncbi Emulsion forming drug delivery system for lipophilic drugs
    Jyoti Wadhwa
    M M College of Pharmacy, M M University, Mullana Ambala, Haryana, India
    Acta Pol Pharm 69:179-91. 2012
    ..a unique and industrially feasible approach to overcome the problem of low oral bioavailability associated with the BCS class II drugs...
  92. ncbi ABCG2 modulates chlorothiazide permeability--in vitro-characterization of its interactions
    Erzsébet Beéry
    SOLVO Biotechnology, Szeged, Hungary
    Drug Metab Pharmacokinet 27:349-53. 2012
    ..It is a Biopharmaceutics Classification System/Biopharmaceutics Drug Distribution and Classification System (BCS/BDDCS) Class IV drug with low bioavailability...
  93. ncbi Screening mammograms in Alzheimer's disease patients
    George M Yousef
    Marshall University, USA
    W V Med J 108:92-5. 2012
    ..In this case, the family opted for breast conserving surgery (BCS) followed by palliative care which brought up the question of whether screening was appropriate with this treatment ..
  94. doi The evolution of therapeutic strategies for biliary tract complications after liver transplantation over a period of 20 years
    M R Gonzalez
    Liver Transplantation Unit, Virgen de la Arrixaca University Hospital, Murcia, Espana
    Transplant Proc 44:2093-5. 2012
    ..as a result of advances in surgical techniques and improved immunosuppressive control, biliary complications (BCs) continue to be the most common cause of morbidity in liver transplant recipients...
  95. doi Inorganic matrices: an answer to low drug solubility problem
    Luana Perioli
    Dipartimento di Chimica e Tecnologia del Farmaco, Universita degli Studi di Perugia, Via del Liceo 1, Perugia 06123, Italy
    Expert Opin Drug Deliv 9:1559-72. 2012
    ..of many orally administered drugs, belonging to class II and IV of the Biopharmaceutics Classification System (BCS)...
  96. pmc Bioelectrical impedance self-measurement protocol development and daily variation between healthy volunteers and breast cancer survivors with lymphedema
    Sheila H Ridner
    1 School of Nursing, Vanderbilt University, Nashville, Tennessee
    Lymphat Res Biol 12:2-9. 2014
    ..Previous studies suggest that less than 50% of breast cancer survivors with lymphedema (BCS-LE) perform prescribed self-care tasks and that even wearing a compression sleeve, the most commonly reported self-..
  97. doi The effects of a 6-month resistance training and dried plum consumption intervention on strength, body composition, blood markers of bone turnover, and inflammation in breast cancer survivors
    Emily Simonavice
    a School of Health and Human Performance, Georgia College and State University, Campus Box 112, Milledgeville, GA 31061, USA
    Appl Physiol Nutr Metab 39:730-9. 2014
    ..DP) consumption on strength, body composition, blood markers of bone, and inflammation in breast cancer survivors (BCS)...
  98. pmc Behcet's disease in budd-chiari syndrome
    Anne Claire Desbois
    Department of Internal Medicine and clinical Immunology APHP, Paris France, Centre de référence des maladies autoimmunes et systémiques rares, Universite Pierre et Marie Curie, Paris 6, Paris, France Laboratory I3 Immunology, Immunopathology, Immunotherapy, UMR CNRS 7211, INSERM U959, Groupe Hospitalier Pitie Salpetriere, DHU I2B Inflammation, Immunopathology, Biotherapy, Universite Pierre et Marie Curie, Paris 6, Paris, France
    Orphanet J Rare Dis 9:104. 2014
    Behcet's disease (BD) is a well-known cause of Budd-Chiari syndrome (BCS). Data are lacking on the presentation and outcome of BCS related to BD.
  99. doi Evaluation of pre-breeding reproductive tract scoring as a predictor of long term reproductive performance in beef heifers
    D E Holm
    Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa Electronic address
    Prev Vet Med 118:56-63. 2015
    ..The effect of RTS on each outcome was adjusted for year of birth, pre-breeding age, BW and body condition score (BCS), and for 24-day anoestrus, bull, gestation length, previous days to calving and previous cow efficiency index, the ..
  100. pmc Survival in stage I-III breast cancer patients by surgical treatment in a publicly funded health care system
    S Fisher
    School of Public Health
    Ann Oncol 26:1161-9. 2015
    ..suggest that patients who receive mastectomy have poorer survival than those who receive breast-conserving surgery (BCS) plus radiotherapy, despite clinically established equivalence...
  101. ncbi Sugars as solid dispersion carrier to improve solubility and dissolution of the BCS class II drug: clotrimazole
    Ashwini Madgulkar
    a Department of Pharmaceutics, AISSMS College of Pharmacy, Pune, Maharashtra, India
    Drug Dev Ind Pharm 42:28-38. 2016
    Solid dispersion of poorly soluble BCS class II drug, clotrimazole, was prepared with the aim of enhancing its dissolution profile...

Research Grants66

  1. Characterization of HIN1 Putative Tumor Suppressor
    Ian Krop; Fiscal Year: 2003
    ..is highly expressed in normal breast epithelial cells, but lost in >90% of primary pre-invasive and invasive BCs and BC cell lines...
  2. Frank Pajonk; Fiscal Year: 2016
    ..serum Epo level correlate with high BCSC burden, nodal status and local control after breast-conserving surgery (BCS) and RT...
  3. Nirmala Ramanujam; Fiscal Year: 2015
    ..Women with operable breast cancer undergo Breast Conserving Surgery (BCS), also called lumpectomy or partial mastectomy...
  4. MULTILEVEL COMPLIANCE MODEL OF BREAST CANCER TREATMENTS
    Mary Fennell; Fiscal Year: 1999
    ..In brief, recommended primary treatment has been breast conserving surgery (BCS) plus radiation therapy (RT), or modified radical mastectomy...
  5. SHABBIR BAKIR BAMBOT; Fiscal Year: 2014
    ..innovative, cost effective and easy to use device for visualizing tumor margins during Breast Conservation Surgery (BCS), a method that is used in about 60-70% percent of breast cancer surgeries...
  6. Intra-operative specimen tomosynthesis for margin assessment in breast surgery
    EMRE TOKER; Fiscal Year: 2009
    ..radiographic margin assessment of surgically excised breast tissue specimens during breast-conserving surgery (BCS)...
  7. CARE, COSTS AND OUTCOMES OF LOCAL BREAST CANCER
    Jeanne Mandelblatt; Fiscal Year: 1999
    ..treatments for local breast cancer in the elderly: modified radical mastectomy (MRM), breast conserving surgery (BCS) with radiotherapy (RT), and BCS without RT...
  8. A Fluorescence Histology System for In Vivo Breast Tumor Margin Assessment
    JONATHAN QUINCY BROWN; Fiscal Year: 2012
    ..women with early stage invasive breast cancer and/or carcinoma in situ (CIS) received breast conserving surgery (BCS). BCS involves removal of malignant tissue with a surrounding margin of normal breast tissue...
  9. TAS::75 0849::TAS SBIR TOPIC 307 PHASE I NOVEL IMAGING AGENTS TO EXPAND THE CLIN
    BRYAN WALSER; Fiscal Year: 2011
    ..The major complication after breast conserving surgery (BCS) is local recurrence of the cancer...
  10. Influence of Exercise and Adiposity on Biomarkers of Breast Cancer Recurrence
    Lisa J Wood; Fiscal Year: 2013
    ..Observational studies suggest that if breast cancer survivors (BCS) can become sufficiently physically active and control their weight, prognosis may improve even further...
  11. LYLE D ISAACS; Fiscal Year: 2016
    ..pharmaceutical industry is that 40-70% of new drug compounds belong to the biopharmaceutics classification system (BCS) class II with such poor aqueous solubility that they cannot be formulated on their own...
  12. Local Therapy of Breast Cancer in Community Populations
    Nancy Keating; Fiscal Year: 2007
    ..conservation offers survival rates equivalent to mastectomy and (b) patients undergoing breast-conserving surgery (BCS) should also receive radiation. These statements are based on clinical trial data; however, only 2...
  13. STEPHEN JONATHAN MACHIN; Fiscal Year: 2015
    ..The British Cohort Study (BCS) and UK National Child Development Study (NCDS) will enable us to estimate these models up to middle age...
  14. Oliver W Press; Fiscal Year: 2015
    ..extend the approach to patients lacking histocompatibility locus antigen (HLA)-matched donors by investigating 131l-BCS in the setting of haplo-identical transplantation for AML, ALL and MDS (Aim 2) and explore the use of 90Yttrium-BC8,..
  15. Richard H Kramer; Fiscal Year: 2014
    The connections between cone photoreceptors and their postsynaptic targets, bipolar and horizontal cells (BCs and HCs), are the first synapses in the visual system...
  16. Jianming Xu; Fiscal Year: 2016
    ..Twist is a DNA-binding transcription factor overexpressed in invasive BCs and a master regulator of EMT and BC Meta...
  17. MARIA EULALIA RUBIO; Fiscal Year: 2016
    ..In the cochlear nucleus (CN), AN fibers bifurcate to innervate multiple cell populations, including bushy cells (BCs) in the ventral CN, and fusiform cells (FCs) in the dorsal CN...
  18. Roles of SRC-3 in Development and Disease
    Jianming Xu; Fiscal Year: 2013
    ..While SRC3 is expressed in the basal cells (BCs) but not expressed in the normal exocrine luminal epithelial cells (ELECs), it is overexpressed in the advanced ..
  19. Richard F Selden; Fiscal Year: 2016
    ..The NetBio platform consists of a ruggedized, analytic instrument that accepts a biochipset (BCS)-shown in Preliminary Studies to purify genomic DNA from clinical samples, amplify, electrophoretically separate ..
  20. Determinants and Correlates of Physical Activity in Breast Cancer Survivors
    SIOBHAN MARIE WHITE; Fiscal Year: 2010
    There are over 2.4 million breast cancer survivors (BCS) in the U.S. accounting for 22% of all cancer survivors [1]. The 5-year survival rate of 88...
  21. Chuanshu Huang; Fiscal Year: 2016
    ..ISO) i a new derivative of stilbene, and isolated from a Chinese herb that has been used in China for treatment of BCs for hundreds of years without understanding of molecular mechanisms...
  22. Jennifer L Maggs; Fiscal Year: 2014
    ..temperamental, cognitive, and family influences on early alcohol use in the MCS and the 1970 British Cohort Study (BCS) with structural equation models;(2) In the BCS and 1958 National Child Development Study (NCDS), examine how ..
  23. Southern Community Cancer Survivorship Study
    Ann Marie Flores; Fiscal Year: 2010
    ..breast cancer specific physical and functional limitations and symptoms among AAs, poor and medically underserved BCS. H1...
  24. Rural Long-Term Cancer Survivors and Contextual Health-related Quality of Life
    LELI PEDRO; Fiscal Year: 2010
    ..Furthermore breast cancer survivors (BCS) make up 41% of all cancer survivors yet this group remains poorly understood in the rural setting...
  25. Family Communication in Coping with Ethnic Minority Breast Cancer Survivors
    Jung won Lim; Fiscal Year: 2010
    How breast cancer survivors (BCS) and their families cope with stress experiences and communicate with each other may influence their quality of life outcomes...
  26. Robert E Marc; Fiscal Year: 2015
    ..gt;12mos of age will receive (1) subretinal injections of Channelrhodopsin2 (ChR2)-AAV targeting bipolar cells (BCs) or AII amacrine cell (ACs). Analyses will follow those established in Aim 1. Signifi- cance...
  27. David J McConkey; Fiscal Year: 2016
    ..of urothelial neoplasia, the determination of whether activating mutations and gene amplifications present in BCs drive cancer progression and serve as potential therapeutic targets, the identification of molecular and biological ..
  28. Brian K Shoichet; Fiscal Year: 2016
    ..In vivo pharmacokinetics. Colloids of several BCS II and IV oral drugs are stable in simulated intestinal fluids...
  29. Blood Cell-Spheres: Growth, Description, and Potential
    AUDREY NADINE JAJOSKY; Fiscal Year: 2013
    ..These advances inspired us to grow "blood cell-spheres" (BCS) using leukemia cells taken from routine patient blood specimens...
  30. RACHEL O WONG; Fiscal Year: 2015
    ..This information is distributed by retinal bipolar cells (BCs) along many anatomically and functionally distinct channels...
  31. Mark F Bear; Fiscal Year: 2016
    DESCRIPTION (provided by applicant): The Brain and Cognitive Sciences (BCS) Graduate Program at the Massachusetts Institute of Technology requests renewal of the training program in the Neurobiology of Learning and Memory (NLM)...
  32. SUZANNE DANIELA CONZEN; Fiscal Year: 2016
    ..studies with long-term clinical follow-up and examined the association between high GR expression in primary BCs and risk of relapse in over 1300 patients...
  33. Enabling family communication about cancer - Do you know your Kin Facts?
    John M Quillin; Fiscal Year: 2013
    ..Specific aims: 1. Assess the effect of the Kin Fact program on communication about FH of BCs and CCs. We will investigate race/ethnicity and education as effect modifiers. 2...
  34. Samuel M Wu; Fiscal Year: 2014
    ..the detailed cellular and synaptic mechanisms underlying center and surround responses of retinal bipolar cells (BCs)...
  35. Maria E Martinez; Fiscal Year: 2014
    ..b>BCs that occur in the post-partum period have more aggressive histopathological features, are more likely to ..
  36. Samuel M Wu; Fiscal Year: 2016
    ..BC types in the three alphaGC circuitries and to identify possible synaptic contacts between rods/cones and BCs and between BCs and alphaGCs;(2) to determine the relative strengths of rod- and cone-mediated inputs to BCs and ..
  37. Birmingham Science Education Partnership: Middle School Inquiry-Based Learning
    J MICHAEL MICHAEL WYSS; Fiscal Year: 2011
    ..The University of Alabama at Birmingham (UAB), Birmingham City Schools (BCS)'and McWane Center have forged an effective alliance that has empowered CORD's SEPA-funded high school ..
  38. Effectiveness Trial of Attention Shaping for Schizophrenia
    Steven M Silverstein; Fiscal Year: 2010
    ..ASP will be integrated within a standard form of social skills training [UCLA Basic Conversation Skills Module (BCS)], and compared to a BCS-alone condition...
  39. Integrative Training Progran in Vision
    Edward H Adelson; Fiscal Year: 2010
    ..The Department of Brain and Cognitive Sciences (BCS) has a very broad range of research and teaching in the vision sciences, with particular expertise in visual ..
  40. METANALYSIS COGNITIVE NEUROIMAGING: METHODS VALIDATIONS
    Peter Fox; Fiscal Year: 2002
    ..semantics) for the behaviors used and mental operations experimentally mapped, termed the Behavioral Coding Scheme (BCS)...
  41. CELLULAR DEFECTS IN NOCTURNAL HEMOGLOBINURIA
    Robert Hartmann; Fiscal Year: 1980
    ..The major thrust will concern an extended study of hepatic venous thrombosis (Budd-Chiari syndrome) (BCS) as a frequent, highly lethal complication of PNH...
  42. Histology-Based Computational Tools for Ultrasonic Differentiation of Neoplasms
    TIMOTHY EDWIN DOYLE; Fiscal Year: 2010
    ..Tissue margin assessments during breast conservation surgery (BCS) are one example...
  43. Menkes protein:copper transport in the pituitary
    TAMI STEVESON; Fiscal Year: 2002
    ..The copper chelators, bathocuproinedisulfonic acid (BCS) and Disulfiram (Antabuse), will be used to determine if a reduction of copper levels affects the behavior of ..
  44. Outcomes of Omission of Radiation With Lumpectomy (BCS) Among Low-Income Women
    Roger Anderson; Fiscal Year: 2007
    ABSTRACT Title: Outcomes of Omission of Radiation With Lumpectomy (BCS) Among Low-Income Women Background: There is little information describing the patterns of health care and outcomes in financially needy women with breast cancer in ..
  45. Matthew F Krummel; Fiscal Year: 2015
    ..However, the molecular natures of individual leukocyte subtypes associated with developing breast cancers (BCs) are inadequately understood...
  46. NEUROENDOCRINE PACERS, PEPTIDES, RECEPTORS, ANTIBODIES
    Felix Strumwasser; Fiscal Year: 1991
    ..2) Determining the structure-activity relationships of the neuropeptide egg-laying hormone (ELH), made by the BCs, by using fragments and modifications of synthetic ELH, in conjunction with behavioral egg-laying assays, ..
  47. NEW HANOVER BREAST CANCER SCREENING PROGRAM
    DANA QUADE; Fiscal Year: 1990
    We propose a comprehensive program to increase and improve breast cancer screening (BCS), including annual clinical breast examination and mammography among women ages 50 to 74 in New Hanover County, NC...
  48. Role of Cellular Lipoprotein in PrPSen>PrPRes Conversion
    Abraham Grossman; Fiscal Year: 2004
    ..This model is composed of proteinase K (pK) sensitive PrP (PrPSen) and a high molecular weight component of BCS that, in combination with RNA, generates a pK-resistant form of PrP (PrPRes)...
  49. BIRMINGHAM SCIENCE EDUCATION PARTNERSHIP (BSEP) PHASE I
    Mary Williams; Fiscal Year: 2004
    ..abstract): The University of Alabama at Birmingham, McWane Science Center and the Birmingham City Schools (BCS) propose a highly coordinated program to provide high school science teachers and their students with a laboratory-..
  50. Breast Tissue ablation by Conductive Heating
    Gal Shafirstein; Fiscal Year: 2007
    ..At these early stages, breast cancer patients can be treated via breast conservation surgery (BCS)...
  51. Insomnia Intervention for Breast Cancer Survivors
    Dana Epstein; Fiscal Year: 2003
    ..efficacy of non-pharmacological treatment for patients most at need and at risk such as breast cancer survivors (BCS)...
  52. PHOTON MIGRATION MEASUREMENTS FOR TISSUE DIAGNOSTICS
    Eva Sevick Muraca; Fiscal Year: 1999
    ..pending), and functional/structural spectroscopic imaging on the basis of tissue optical properties (NSF-BCS- 9358254)...
  53. Molecular pathogenesis of focal cortical dysplasias
    Peter B Crino; Fiscal Year: 2010
    ..similar histological features including cells exhibiting cytomegaly and abnormal morphology called balloon cells (BCs)...
  54. Comparison of Aerobic and Resistance Exercise in Older Breast Cancer Survivors
    Kerri Winters Stone; Fiscal Year: 2009
    ..effects of aerobic exercise and resistance exercise for inactive older (aged 65+) breast cancer survivors (BCS) at least two years post- treatment...
  55. PREDICTORS OF RELAPSE TO SMOKING IN LUNG CANCER
    Mario Schootman; Fiscal Year: 2005
    ..abstract_text> ..
  56. Radiation Therapy in Older Breast Cancer Patients
    Mario Schootman; Fiscal Year: 2002
    ..are less likely than their urban counterparts to receive radiation therapy (XRT) following conservative surgery (BCS) for stage I-II breast cancer. XRT is recommended by the NIH for these women, but rural elderly women are 1...
  57. Gis, multilevel modeling and breast cancer screening
    Mario Schootman; Fiscal Year: 2002
    ..Few studies focusing on breast cancer screening have taken this approach, which we, and others feel is warranted. ..
  58. ACYLCOA FORMATION--COVALENT BINDING, PHARMACOKINETICS
    Leslie Benet; Fiscal Year: 2002
    ....
  59. Substrate requirements of the bile acid transporter
    JAMES POLLI; Fiscal Year: 2009
    ..This systematic and progressive approach will serve as a prototypical method to elucidate the substrate requirements of other solute carrier (SLC) proteins. ..
  60. Transporter-Enzyme Interplay Evaluation via Microfluidiic HTS Cell Culture Device
    Leslie Benet; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  61. Osteoporosis Prevention in Early Stage Breast Cancer
    Dawn Hershman; Fiscal Year: 2006
    ..abstract_text> ..
  62. Geography of Amputations Among African Americans
    Mario Schootman; Fiscal Year: 2005
    ..abstract_text> ..
  63. Multilevel Model of Breast Cancer Follow-up Care
    Mario Schootman; Fiscal Year: 2005
    ..abstract_text> ..
  64. GIS and Breast Cancer Screening in Saint Louis
    Mario Schootman; Fiscal Year: 2004
    ..abstract_text> ..