UVSSA

Summary

Gene Symbol: UVSSA
Description: UV stimulated scaffold protein A
Alias: KIAA1530, UVSS3, UV-stimulated scaffold protein A
Species: human

Top Publications

  1. doi Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair
    Yuka Nakazawa
    Nagasaki University Research Centre for Genomic Instability and Carcinogenesis, Nagasaki, Japan
    Nat Genet 44:586-92. 2012
  2. doi UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair
    Petra Schwertman
    Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands
    Nat Genet 44:598-602. 2012
  3. doi Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair
    Xue Zhang
    Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
    Nat Genet 44:593-7. 2012
  4. pmc KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR)
    Jia Fei
    Department of Experimental Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Biol Chem 287:35118-26. 2012
  5. pmc UVSSA and USP7, a new couple in transcription-coupled DNA repair
    Petra Schwertman
    Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
    Chromosoma 122:275-84. 2013
  6. pmc Stabilization of Ultraviolet (UV)-stimulated Scaffold Protein A by Interaction with Ubiquitin-specific Peptidase 7 Is Essential for Transcription-coupled Nucleotide Excision Repair
    Mitsuru Higa
    From the Graduate School of Frontier Biosciences, Osaka University, Yamadaoka 1 3, Suita, Osaka 565 0871, Japan
    J Biol Chem 291:13771-9. 2016

Detail Information

Publications7

  1. doi Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair
    Yuka Nakazawa
    Nagasaki University Research Centre for Genomic Instability and Carcinogenesis, Nagasaki, Japan
    Nat Genet 44:586-92. 2012
    ..Using exome sequencing, we determine that mutations in the UVSSA gene (formerly known as KIAA1530) cause UV(S)S-A...
  2. doi UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair
    Petra Schwertman
    Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands
    Nat Genet 44:598-602. 2012
    ..Using a SILAC-based proteomic approach, we identified UVSSA (formerly known as KIAA1530) as part of a UV-induced ubiquitinated protein complex. Knockdown of UVSSA resulted in TC-NER deficiency...
  3. doi Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair
    Xue Zhang
    Graduate School of Frontier Biosciences, Osaka University, Osaka, Japan
    Nat Genet 44:593-7. 2012
    ..The predicted human gene UVSSA (formerly known as KIAA1530)(7) corrects defective TCR in UV(S)S-A cells...
  4. pmc KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR)
    Jia Fei
    Department of Experimental Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    J Biol Chem 287:35118-26. 2012
    ..Here, we report the characterization of KIAA1530, an evolutionarily conserved protein that participates in this pathway through its interaction with CSA and the ..
  5. pmc UVSSA and USP7, a new couple in transcription-coupled DNA repair
    Petra Schwertman
    Department of Genetics and Netherlands Proteomics Centre, Centre for Biomedical Genetics, Erasmus Medical Centre, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
    Chromosoma 122:275-84. 2013
    ..will focus on two new players involved in TC-NER which were recently identified: UV-stimulated scaffold protein A (UVSSA) and ubiquitin-specific protease 7 (USP7)...
  6. pmc Stabilization of Ultraviolet (UV)-stimulated Scaffold Protein A by Interaction with Ubiquitin-specific Peptidase 7 Is Essential for Transcription-coupled Nucleotide Excision Repair
    Mitsuru Higa
    From the Graduate School of Frontier Biosciences, Osaka University, Yamadaoka 1 3, Suita, Osaka 565 0871, Japan
    J Biol Chem 291:13771-9. 2016
    ..UV-sensitive syndrome consists of three genetic complementation groups caused by mutations in the CSA, CSB, and UVSSA genes...