PRG 3

Summary

Gene Symbol: PRG 3
Description: phospholipid phosphatase related 1
Alias: LPPR1, PRG-3, phospholipid phosphatase-related protein type 1, lipid phosphate phosphatase-related protein type 1, plasticity related gene 3, plasticity-related gene 3 protein
Species: human

Top Publications

  1. ncbi Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene family
    Nicolai E Savaskan
    PRGs Research Group, Institute of Cell Biology and Neurobiology, Center for Anatomy, Philippstrasse 12, Charité University Medical School Berlin, D 10115 Berlin, Germany
    Eur J Neurosci 19:212-20. 2004
  2. ncbi A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting
    Anja U Bräuer
    Institute of Anatomy, Department of Cell Biology and Neurobiology, Philippstr 12, Humboldt University Medical School Charité, D 10115 Berlin, Germany
    Nat Neurosci 6:572-8. 2003
  3. doi Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus
    Hong Ni
    Neurology Laboratory, Soochow University Affiliated Children s Hospital, Laboratory of Aging and Nervous Diseases, Soochow University, Suzhou 215003, China
    Toxicol Lett 217:162-9. 2013
  4. ncbi Poliomyelitis in intraspinally inoculated poliovirus receptor transgenic mice
    A M Deatly
    Viral Vaccine Research, Wyeth Lederle Vaccines and Pediatrics, 401 North Middletown Road, Pearl River, New York, 10965, USA
    Virology 255:221-7. 1999
  5. ncbi Dynamic pattern of mRNA expression of plasticity-related gene-3 (PRG-3) in the mouse cerebral cortex during development
    Wei Zhi Wang
    Department of Human Anatomy and Genetics, South Parks Road, University of Oxford, UK
    Brain Res Bull 66:454-60. 2005
  6. pmc Unidirectional binding of clostridial collagenase to triple helical substrates
    Sagaya Theresa Leena Philominathan
    Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Arkansas 72701, USA
    J Biol Chem 284:10868-76. 2009
  7. doi Dynamic pattern of gene expression of ZnT-4, caspase-3, LC3, and PRG-3 in rat cerebral cortex following flurothyl-induced recurrent neonatal seizures
    Hong Ni
    Neurology Laboratory, Soochow University Affiliated Children s Hospital, No 303, Jingde Road, Suzhou, 215003, People s Republic of China
    Biol Trace Elem Res 143:1607-15. 2011

Research Grants

  1. Hyunyoung Jeong; Fiscal Year: 2015

Scientific Experts

  • N E Savaskan
  • Hyunyoung Jeong
  • Hong Ni
  • Xing Feng
  • Sagaya Theresa Leena Philominathan
  • Wei Zhi Wang
  • Anja U Bräuer
  • Qi Sun
  • Le ling Zhang
  • Shou Yun Ren
  • Tian Tian
  • Zhuo jun Xiao
  • Mei Fang Jin
  • Lu yang Tao
  • Soenke Seifert
  • Takaki Koide
  • Hiroyuki Yasui
  • Kentaro Hamada
  • Osamu Matsushita
  • Joshua Sakon
  • A M Deatly
  • Zoltan Molnar
  • Olaf Ninnemann
  • Siegfried Prehn
  • Hartmut Kuhn
  • Robert Nitsch
  • R E Taffs
  • J C Crowley
  • T McWilliams
  • J M McAuliffe
  • J W Coleman
  • A Cupo
  • G McMullen
  • V Jayarama

Detail Information

Publications7

  1. ncbi Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene family
    Nicolai E Savaskan
    PRGs Research Group, Institute of Cell Biology and Neurobiology, Center for Anatomy, Philippstrasse 12, Charité University Medical School Berlin, D 10115 Berlin, Germany
    Eur J Neurosci 19:212-20. 2004
    ..In summary, our findings feature a new member of the PRG family which shows dynamic expression regulation during brain development and neuronal excitation...
  2. ncbi A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting
    Anja U Bräuer
    Institute of Anatomy, Department of Cell Biology and Neurobiology, Philippstr 12, Humboldt University Medical School Charité, D 10115 Berlin, Germany
    Nat Neurosci 6:572-8. 2003
    ..Thus, we propose a novel mechanism by which axons are able to control phospholipid-mediated signaling and overcome the growth-inhibiting, phospholipid-rich environment of the extracellular space...
  3. doi Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus
    Hong Ni
    Neurology Laboratory, Soochow University Affiliated Children s Hospital, Laboratory of Aging and Nervous Diseases, Soochow University, Suzhou 215003, China
    Toxicol Lett 217:162-9. 2013
    ....
  4. ncbi Poliomyelitis in intraspinally inoculated poliovirus receptor transgenic mice
    A M Deatly
    Viral Vaccine Research, Wyeth Lederle Vaccines and Pediatrics, 401 North Middletown Road, Pearl River, New York, 10965, USA
    Virology 255:221-7. 1999
    ..However, there is a difference in the rate of accumulation of clinical signs. The time to onset of disease is shorter for TGM-PRG-3 than TGM-PRG-1 mice. Thus, receptor dosage affects the rate of appearance of poliomyelitis in these mice...
  5. ncbi Dynamic pattern of mRNA expression of plasticity-related gene-3 (PRG-3) in the mouse cerebral cortex during development
    Wei Zhi Wang
    Department of Human Anatomy and Genetics, South Parks Road, University of Oxford, UK
    Brain Res Bull 66:454-60. 2005
    ..Here, for the first time, we report the mRNA expression pattern of PRG-3 in the developing and adult mouse cerebral cortex...
  6. pmc Unidirectional binding of clostridial collagenase to triple helical substrates
    Sagaya Theresa Leena Philominathan
    Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Arkansas 72701, USA
    J Biol Chem 284:10868-76. 2009
    ....
  7. doi Dynamic pattern of gene expression of ZnT-4, caspase-3, LC3, and PRG-3 in rat cerebral cortex following flurothyl-induced recurrent neonatal seizures
    Hong Ni
    Neurology Laboratory, Soochow University Affiliated Children s Hospital, No 303, Jingde Road, Suzhou, 215003, People s Republic of China
    Biol Trace Elem Res 143:1607-15. 2011
    ..The results suggest that the disturbed expression pattern of the four genes might play a role in the pathophysiology of recurrent neonatal seizure-induced acute and long-term brain damage...

Research Grants1

  1. Hyunyoung Jeong; Fiscal Year: 2015
    ..The knowledge obtained from this study can be expanded to optimize drug therapy in other groups of women, such as oral contraceptive users, thus benefiting women in general. ..