NUCKS

Summary

Gene Symbol: NUCKS
Description: nuclear casein kinase and cyclin dependent kinase substrate 1
Alias: JC7, NUCKS, nuclear ubiquitous casein and cyclin-dependent kinase substrate 1, nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate, potential LAG1 interactor
Species: human

Top Publications

  1. ncbi Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo
    A C Ostvold
    Department of Medical Biochemistry, University of Oslo, Norway
    Eur J Biochem 268:2430-40. 2001
  2. pmc Identification and confirmation of a module of coexpressed genes
    H Garrett R Thompson
    Department of Biomedical Engineering, University of California Irvine, Irvine, California 92697, USA
    Genome Res 12:1517-22. 2002
  3. ncbi A putative DNA-binding domain in the NUCKS protein
    Kirsten Grundt
    Department of Medical Biochemistry, University of Oslo, Box 1115 Blindern, Oslo, Norway
    Arch Biochem Biophys 407:168-75. 2002
  4. ncbi Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species
    Kirsten Grundt
    Department of Medical Biochemistry, Institute Group of Basic Medical Sciences, University of Oslo, Norway
    Biochem Biophys Res Commun 323:796-801. 2004
  5. ncbi Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS
    Kirsten Grundt
    Department of Biochemistry, Institute of Basic Medical Sciences, University of Oslo, P O Box 1112, Blindern, 0317 Oslo, Norway
    Biochim Biophys Acta 1773:1398-406. 2007
  6. doi Constitutive and dynamic phosphorylation and acetylation sites on NUCKS, a hypermodified nuclear protein, studied by quantitative proteomics
    Jacek R Wisniewski
    Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Martinsried, Germany
    Proteins 73:710-8. 2008
  7. doi NUCKS1 overexpression is a novel biomarker for recurrence-free survival in cervical squamous cell carcinoma
    Lina Gu
    Department of Gynecology, The Third Affiliated Hospital, Harbin Medical University, Baojian Road 6, Nangang District, 150081, Harbin, China
    Tumour Biol 35:7831-6. 2014
  8. pmc Inhibition of NUCKS Facilitates Corneal Recovery Following Alkali Burn
    Ming Wai Poon
    Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
    Sci Rep 7:41224. 2017
  9. pmc Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes
    Vladimir Vacic
    Department of Computer Science, Columbia University, New York, NY, USA
    Hum Mol Genet 23:4693-702. 2014
  10. doi NUCKS is a positive transcriptional regulator of insulin signaling
    Beiying Qiu
    Institute of Molecular and Cell Biology, Agency for Science, Technology and Research A STAR, Singapore 138673, Singapore
    Cell Rep 7:1876-86. 2014

Research Grants

  1. Claudia Wiese; Fiscal Year: 2016
  2. Role of H11 kinase in cardiac cell growth
    Christophe Depre; Fiscal Year: 2007

Scientific Experts

  • Denzil Garteiz Martínez
  • Kirsten Grundt
  • Linda M Sargent
  • Jacek R Wisniewski
  • Yukinori Okada
  • Jonathan B Savitz
  • Beiying Qiu
  • Claudia Wiese
  • Vinay Tergaonkar
  • Christophe Depre
  • Yiannis Drosos
  • Piotr Ziółkowski
  • Weiping Han
  • Anne Carine Østvold
  • Ming Wai Poon
  • Xi Chen Zhu
  • Jae Youn Cheong
  • Hua Shen
  • Ling Wang
  • YangBo Yue
  • David Schild
  • Stanley G Leung
  • Lasse Pihlstrøm
  • Soriul Kim
  • Ann C Parplys
  • Qiling Zhou
  • Joy Lim
  • Xiaohe Shi
  • Ming Yang
  • Nema Ali Soliman
  • Vladimir Vacic
  • Krzysztof Zduniak
  • Lina Gu
  • Katarzyna Hotowy
  • F Akbari Moqadam
  • Akifumi Kikuchi
  • Jielin Sun
  • Zhengguang Guo
  • Mirsini Kouloukoussa
  • Vassiliki Aleporou-Marinou
  • Sophia Havaki
  • Evangelos Marinos
  • Beata Osiecka
  • Arianna Tucci
  • Henry Houlden
  • Coro Paisan-Ruiz
  • Andrew B Singleton
  • Wataru Satake
  • Javier Simon-Sanchez
  • Meng Shan Tan
  • Zhendong Yu
  • Peng Qin
  • David S H Wong
  • Wei Zhang
  • Ian Y Wong
  • Dan Jiang
  • Yuelin Zhang
  • Hung Fat Tse
  • Sumit Chanda
  • Chen Chen Tan
  • Jin Tai Yu
  • Qing Li
  • Qizhou Lian
  • Lan Tan
  • Lei Cao
  • Teng Jiang
  • Hui Fu Wang
  • Huan Lu
  • Kuang Yu Jen
  • Jun Hyung Park
  • Sun Kim Soon
  • Kap Seok Yang
  • Wei tao Liu
  • Zhong Jiao Lu
  • Dong Kyu Kim
  • Jung Hoon Woo
  • Xiaobo Yu
  • Rong Peng
  • Xiao Yi Sun
  • Lin Wang
  • Marie Yeo
  • Young Bae Kim
  • Hee Jeong Wang
  • Song Ju Yang
  • Cheng Fei Jiang
  • Yong qian Shu
  • Jun ying Li
  • Lan Cheng
  • Xin Ge
  • Zhu Mei Shi

Detail Information

Publications41

  1. ncbi Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo
    A C Ostvold
    Department of Medical Biochemistry, University of Oslo, Norway
    Eur J Biochem 268:2430-40. 2001
    We have isolated and characterized a cDNA encoding a mammalian nuclear phosphoprotein NUCKS, previously designated P1...
  2. pmc Identification and confirmation of a module of coexpressed genes
    H Garrett R Thompson
    Department of Biomedical Engineering, University of California Irvine, Irvine, California 92697, USA
    Genome Res 12:1517-22. 2002
    ..contains at least six members that are believed to be involved in either transcritional regulation (PDEF, H2AFO, NUCKS) or the ubiquitin proteasome pathway (PSMD7, SQSTM1, FLJ10111)...
  3. ncbi A putative DNA-binding domain in the NUCKS protein
    Kirsten Grundt
    Department of Medical Biochemistry, University of Oslo, Box 1115 Blindern, Oslo, Norway
    Arch Biochem Biophys 407:168-75. 2002
    We have studied the DNA-binding properties of a NUCKS-derived, synthetic peptide containing an extended GRP motif. This peptide binds to random-sequence DNA, but did not bind preferentially to poly(dA-dT)...
  4. ncbi Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species
    Kirsten Grundt
    Department of Medical Biochemistry, Institute Group of Basic Medical Sciences, University of Oslo, Norway
    Biochem Biophys Res Commun 323:796-801. 2004
    The NUCKS gene is located on human chromosome 1q32.1 and consists of seven exons and six introns. The gene lacks a TATA box but contains two Inr elements, two GC boxes, and one consensus-binding site for E2F-1...
  5. ncbi Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS
    Kirsten Grundt
    Department of Biochemistry, Institute of Basic Medical Sciences, University of Oslo, P O Box 1112, Blindern, 0317 Oslo, Norway
    Biochim Biophys Acta 1773:1398-406. 2007
    Immunofluorescence analyses show that the vertebrate specific and DNA-binding protein NUCKS is distributed throughout the cytoplasm in mitotic cells and targeted to the reforming nuclei in late telophase of the cell cycle...
  6. doi Constitutive and dynamic phosphorylation and acetylation sites on NUCKS, a hypermodified nuclear protein, studied by quantitative proteomics
    Jacek R Wisniewski
    Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Martinsried, Germany
    Proteins 73:710-8. 2008
    Nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) is a 27 kDa chromosomal protein of unknown function...
  7. doi NUCKS1 overexpression is a novel biomarker for recurrence-free survival in cervical squamous cell carcinoma
    Lina Gu
    Department of Gynecology, The Third Affiliated Hospital, Harbin Medical University, Baojian Road 6, Nangang District, 150081, Harbin, China
    Tumour Biol 35:7831-6. 2014
    ..060 to 4.535; P = 0.034). In conclusion, NUCKS1 overexpression may be associated with tumour progression and recurrence in CSCCs and may thus serve as a new molecular marker for the prediction of RFS in these patients...
  8. pmc Inhibition of NUCKS Facilitates Corneal Recovery Following Alkali Burn
    Ming Wai Poon
    Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
    Sci Rep 7:41224. 2017
    ..Nuclear Ubiquitous Casein and cyclin-dependent Kinase Substrate (NUCKS) is a key chromatin modifier and transcriptional regulator of metabolic signaling...
  9. pmc Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes
    Vladimir Vacic
    Department of Computer Science, Columbia University, New York, NY, USA
    Hum Mol Genet 23:4693-702. 2014
    ..Our results highlight the power of our haplotype association method, particularly useful in studies of founder populations, and reaffirm the benefits of studying complex diseases in Ashkenazi Jewish cohorts. ..
  10. doi NUCKS is a positive transcriptional regulator of insulin signaling
    Beiying Qiu
    Institute of Molecular and Cell Biology, Agency for Science, Technology and Research A STAR, Singapore 138673, Singapore
    Cell Rep 7:1876-86. 2014
    ..We now find that NUCKS is a transcriptional regulator of the insulin signaling components, including the insulin receptor (IR)...
  11. ncbi The comparison of nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) with Ki67 proliferation marker expression in common skin tumors
    Krzysztof Zduniak
    Prof dr Piotr Ziółkowski Department of Pathology Wroclaw Medical University 1 Marcinkowskiego 50 368 Wrocław, Poland tel 48 71 784 12 12 fax 48 71 784 00 57 e mail
    Pol J Pathol 65:48-54. 2014
    Nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) is a chromosomal protein of unknown function...
  12. doi Genetic variants at 1q32.1, 10q11.2 and 19q13.41 are associated with prostate-specific antigen for prostate cancer screening in two Korean population-based cohort studies
    Soriul Kim
    Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea Institute for Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Republic of Korea
    Gene 556:199-205. 2015
    ..We suggest that our results for some but not all PCa risk SNPs to be associated with PSA levels could be used as an evidence for the advance of individual PCa screening strategies, such as applying a personalized cutoff value for PSA...
  13. doi NUCKS: a potential biomarker in cancer and metabolic disease
    Beiying Qiu
    Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, 138673, Singapore
    Clin Sci (Lond) 128:715-21. 2015
    Nuclear, casein kinase and cyclin-dependent kinase substrate (NUCKS), a protein similar to the HMG (high-mobility group) protein family, is one of the most modified proteins in the mammalian proteome...
  14. doi Fine mapping and resequencing of the PARK16 locus in Parkinson's disease
    Lasse Pihlstrøm
    1 Department of Neurology, Oslo University Hospital, Oslo, Norway 2 University of Oslo, Institute of Clinical Medicine, Oslo, Norway
    J Hum Genet 60:357-62. 2015
    ..Comparing our results with previous work, allelic heterogeneity at PARK16 appears likely, and further studies are warranted to disentangle the complex patterns of association and pinpoint the functionally relevant variants. ..
  15. doi Hypothalamic NUCKS regulates peripheral glucose homoeostasis
    Beiying Qiu
    Institute of Molecular and Cell Biology, Agency for Science, Technology and Research A STAR, Singapore
    Biochem J 469:391-8. 2015
    Nuclear ubiquitous casein and cyclin-dependent kinase substrate (NUCKS) is highly expressed in the brain and peripheral metabolic organs, and regulates transcription of a number of genes involved in insulin signalling...
  16. pmc NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability
    Ann C Parplys
    Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Nucleic Acids Res 43:9817-34. 2015
    ..Our results show that NUCKS1 is a chromatin-associated protein with a role in the DNA damage response and in HR, a DNA repair pathway critical for tumor suppression. ..
  17. doi Association of Parkinson's Disease GWAS-Linked Loci with Alzheimer's Disease in Han Chinese
    Xi Chen Zhu
    Department of Neurology, Qingdao Municipal Hospital, Nanjing Medical University, Qingdao, China
    Mol Neurobiol 54:308-318. 2017
    ..Our results first time indicated rs76904798 of LRRK2 is also a common risk genetic variant for LOAD susceptibility in a northern Han Chinese people...
  18. doi Association of three candidate genetic variants in RAB7L1/NUCKS1, MCCC1 and STK39 with sporadic Parkinson's disease in Han Chinese
    Ling Wang
    Department of Neurology, West China Hospital, Sichuan University, Sichuan, 610041, Sichuan Province, People s Republic of China
    J Neural Transm (Vienna) 123:425-30. 2016
    ..Our study provides strong support for the susceptibility role of rs823118 and rs12637471 in sporadic PD in a Han Chinese population...
  19. doi Identification of NUCKS1 as a putative oncogene and immunodiagnostic marker of hepatocellular carcinoma
    Jae Youn Cheong
    Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea Genome Research Center for Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea Electronic address
    Gene 584:47-53. 2016
    ..NUCKS1 was identified as a potential oncogene at chromosomal 1q32.1 in patients with HCC, and it might be a valuable immunodiagnostic marker for HCC. ..
  20. pmc MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer
    Hua Shen
    Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, China
    Oncotarget 7:20728-42. 2016
    ..Identification of a novel miRNA-mediated pathway that regulates chemosensitivity in lung cancer will facilitate the development of novel therapeutic strategies in the future. ..
  21. pmc Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice
    YangBo Yue
    Department of Organismal Systems and Bioresilience, Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Oncotarget . 2016
    ..We propose that, in the context of Trp53 deficiency, wild type levels of Nucks1 are required to suppress radiation-induced TL, likely through the role of the NUCKS1 protein in the DNA damage response...
  22. doi Identification of kinases phosphorylating 13 sites in the nuclear, DNA-binding protein NUCKS
    Kirsten Grundt
    University of Oslo, Institute of Basic Medical Sciences, Department of Biochemistry, P O Box 1112, Blindern N 0317, Oslo, Norway
    Biochim Biophys Acta . 2016
    b>NUCKS is a vertebrate specific, nuclear and DNA-binding phospho protein. The protein is highly expressed in rapidly dividing cells, and is overexpressed in a number of cancer tissues...
  23. ncbi Effect of NUCKS-1 overexpression on cytokine profiling in obese women with breast cancer
    Nema Ali Soliman
    Departments of Medical Biochemistry, 2Departments of General Surgery, Faculty of Medicine, Tanta University, Tanta, Egypt E mail mail com
    Asian Pac J Cancer Prev 15:837-45. 2014
    ..The nuclear, casein kinase and cyclin-dependent kinase substrate-1 (NUCKS-1), is a nuclear DNA-binding protein that has been implicated in several human cancers, including breast cancer.
  24. doi Dynamic expression of the vertebrate-specific protein Nucks during rodent embryonic development
    Yiannis Drosos
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistimioupoli, 15701 Ilissia, Greece Electronic address
    Gene Expr Patterns 14:19-29. 2014
    The nuclear casein kinase and cyclin-dependent kinase substrate 1 (NUCKS) is a highly phosphorylated nuclear protein that is overexpressed in many types of cancer...
  25. pmc Screening E3 substrates using a live phage display library
    Zhengguang Guo
    Department of Physiology and Pathophysiology, National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences School of Basic Medicine, Peking Union Medical College, Beijing, China Department of Core Instrument Facility, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences School of Basic Medicine, Peking Union Medical College, Beijing, China
    PLoS ONE 8:e76622. 2013
    ..The whole strategy is rather simple and efficient. Non-degradation substrates can be discovered. This strategy can be extended to any E3s as long as the E3 does not ubiquitinate the empty phage. ..
  26. doi Combined evaluation of the expression of NUCKS and Ki-67 proteins as independent prognostic factors for patients with gastric adenocarcinoma
    Ming Yang
    Department of Gastrointestinal Medical Oncology, The Affiliated Tumour Hospital of Harbin Medical University, Harbin, Heilongjiang, China
    Tumour Biol 35:7505-12. 2014
    Nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) has been recently documented in various malignancies. However, data regarding the expression and prognostic value of NUCKS in gastric adenocarcinoma are limited...
  27. pmc Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities
    Jonathan Savitz
    Laureate Institute for Brain Research, Tulsa, OK 74136, USA
    Brain Behav Immun 31:161-71. 2013
    ..Our results raise the possibility that molecular-level immune dysfunction can be mapped onto macro-level neuroimaging abnormalities, potentially elucidating a mechanism by which inflammation leads to depression...
  28. pmc NUCKS overexpression in breast cancer
    Yiannis Drosos
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistimioupoli, 15701 Ilissia, Greece
    Cancer Cell Int 9:19. 2009
    b>NUCKS (Nuclear, Casein Kinase and Cyclin-dependent Kinase Substrate) is a nuclear, DNA-binding and highly phosphorylated protein...
  29. doi Identification of NUCKS1 as a colorectal cancer prognostic marker through integrated expression and copy number analysis
    Akifumi Kikuchi
    Department of Surgical Oncology, Graduate School, Tokyo Medical and Dental University, 1 5 45 Yushima, Bunkyo ku, Tokyo, Japan
    Int J Cancer 132:2295-302. 2013
    ..The overexpression of NUCKS1 in cancer cells could be used as a CRC prognostic marker and might also be a target for treatment of this disease...
  30. doi Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population
    Jielin Sun
    Center for Cancer Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Hum Genet 132:423-9. 2013
    ..Identification of these genetic markers provides new insight into the molecular mechanisms of PSA. Taking individual variation into account, these genetic variants may improve the performance of PSA to predict prostate cancer...
  31. ncbi [Cyst of Nucks canal associated with recurrent inguinal hernia]
    Denzil Garteiz Martínez
    Hospital Angeles Lomas, Huixquilucan, Estado de Mexico
    Ginecol Obstet Mex 81:52-6. 2013
    ..We report the case of a woman with a cyst of Nuck that presented as a recurrent inguinal hernia. Discussion is centered on the embryologic, anatomic, clinical and therapeutic aspects of this condition...
  32. doi MiR-125b, miR-100 and miR-99a co-regulate vincristine resistance in childhood acute lymphoblastic leukemia
    F Akbari Moqadam
    Department of Pediatric Oncology and Hematology, Erasmus MC Sophia Children s Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Leuk Res 37:1315-21. 2013
    ..05). The concerted function of miR-125b in combination with miR-99a and/or miR-100 illustrates the complexity of vincristine-resistant pediatric ALL...
  33. doi Immunocytochemical studies on the nuclear ubiquitous casein and cyclin-dependent kinases substrate following 5-aminolevulinicacid-mediated photodynamic therapy on MCF-7 cells
    Katarzyna Hotowy
    Department of Clinical Biochemistry, Wroclaw Medical University, 50 367 Wrocław, Poland
    Photodiagnosis Photodyn Ther 10:518-25. 2013
    Recent data indicates that nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) may play role in tumor growth...
  34. pmc Identification of nine novel loci associated with white blood cell subtypes in a Japanese population
    Yukinori Okada
    Laboratory for Statistical Analysis, Center for Genomic Medicine, Institute of Physical and Chemical Research, Yokohama, Japan
    PLoS Genet 7:e1002067. 2011
    ..This study should contribute to the understanding of the genetic backgrounds of the WBC subtypes and hematological traits...
  35. pmc Genetic variability at the PARK16 locus
    Arianna Tucci
    Department of Molecular Neuroscience and Reta Lila Weston Institute, UCL Institute of Neurology, London, UK
    Eur J Hum Genet 18:1356-9. 2010
    ....
  36. pmc Immunohistochemical and proteomic evaluation of nuclear ubiquitous casein and cyclin-dependent kinases substrate in invasive ductal carcinoma of the breast
    Piotr Ziółkowski
    Department of Pathology, Wrocław Medical University, 1 Marcinkowskiego Street, 50 368 Wroclaw, Poland
    J Biomed Biotechnol 2009:919645. 2009
    Nuclear ubiquitous casein and cyclin-dependent kinases substrate (NUCKS) is 27 kDa chromosomal protein of unknown function...
  37. doi Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
    Wataru Satake
    Division of Neurology Molecular Brain Science, Kobe University Graduate School of Medicine, Kobe, Japan
    Nat Genet 41:1303-7. 2009
    ..Our results identify two new PD susceptibility loci, show involvement of autosomal dominant parkinsonism loci in typical PD and suggest that population differences contribute to genetic heterogeneity in PD...
  38. pmc Genome-wide association study reveals genetic risk underlying Parkinson's disease
    Javier Simon-Sanchez
    Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA
    Nat Genet 41:1308-12. 2009
    ..14, P = 1.55 x 10(-5)). These data demonstrate an unequivocal role for common genetic variants in the etiology of typical PD and suggest population-specific genetic heterogeneity in this disease...
  39. doi Chromosomal changes in high- and low-invasive mouse lung adenocarcinoma cell strains derived from early passage mouse lung adenocarcinoma cell strains
    Linda M Sargent
    National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Toxicol Appl Pharmacol 233:81-91. 2008
    ..analysis and confirmation by real time PCR demonstrated increased expression of COX-2, Translin (TB-RBP), DYRK3, NUCKS and Tubulin-alpha4 genes in the high-invasive cell strains...
  40. ncbi Cell adhesion molecule SC1/DMGRASP is expressed on growing axons of retina ganglion cells and is involved in mediating their extension on axons
    G E Pollerberg
    Max Planck Institute for Developmental Biology, Department of Biochemistry, Tubingen, Germany
    Dev Biol 165:670-87. 1994
    ..including the N-terminal amino acid sequence, with a cell adhesion molecule termed DM-GRASP, SC1, BEN, and JC7. It can therefore be considered identical with this molecule and is referred to as SC1/DMGRASP...

Research Grants2

  1. Claudia Wiese; Fiscal Year: 2016
    ..Nuclear Ubiquitous Casein and Cyclin-dependent Kinases Substrate (NUCKS) is a 27 kD, DNA-binding and vertebrate-specific protein with unknown function...
  2. Role of H11 kinase in cardiac cell growth
    Christophe Depre; Fiscal Year: 2007
    ..Putative interactions include the nuclear casein kinase II (NUCKS II), a stimulator of cell growth, the protein HSP27, a stimulator of cell survival, and the nucleosome assembly ..