MIRLET7D

Summary

Gene Symbol: MIRLET7D
Description: microRNA let-7d
Alias: LET7D, MIRNLET7D, hsa-let-7d, let-7d
Species: human

Top Publications

  1. pmc Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7
    Boxing Su
    Department of Urology, Peking University First Hospital and the Institute of Urology, Peking University, Beijing 100034, China
    Mol Cancer 13:206. 2014
  2. doi Circulating MicroRNA Let-7d in Attention-Deficit/Hyperactivity Disorder
    Li Hui Wu
    Department of Children s Health Care, Yuying Children s Hospital, Wenzhou Medical University, 109 West Xueyuan Road, Wenzhou, 325003, People s Republic of China
    Neuromolecular Med 17:137-46. 2015
  3. pmc Circulating microRNAs as potential biomarkers for endometriosis
    SiHyun Cho
    Department of Obstetrics and Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea
    Fertil Steril 103:1252-60.e1. 2015
  4. doi Let-7 related genetic variation and risk of metabolic syndrome in a Chinese population
    Yu Xiang Yan
    Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, China
    Endocr J 62:887-96. 2015
  5. doi Let-7d miRNA Shows Both Antioncogenic and Oncogenic Functions in Osteosarcoma-Derived 3AB-OS Cancer Stem Cells
    Riccardo Di Fiore
    Laboratory of Biochemistry, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Polyclinic, Palermo, Italy
    J Cell Physiol 231:1832-41. 2016
  6. pmc Plasma microRNAs are associated with acute exacerbation in idiopathic pulmonary fibrosis
    Haiyan Min
    Department of Respiratory Medicine, Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing, China
    Diagn Pathol 11:135. 2016
  7. pmc Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1
    Benjamin Boyerinas
    Feinberg School of Medicine, Division Hematology Oncology, Northwestern University, Chicago, IL 60611, USA
    Int J Cancer 130:1787-97. 2012
  8. doi Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer
    Charn Jung Chang
    Department of Pharmacy Practice, Tri Service General Hospital and National Defense Medical Center, Taipei, Taiwan, ROC
    Oncol Rep 26:1003-10. 2011
  9. doi Olea europaea leaf extract alters microRNA expression in human glioblastoma cells
    Berrin Tunca
    Department of Medical Biology, Medical Faculty, Uludag University, Bursa, Turkey
    J Cancer Res Clin Oncol 138:1831-44. 2012
  10. pmc The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    Yong Sun Lee
    Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908, USA
    Genes Dev 21:1025-30. 2007

Scientific Experts

  • Zhi Qian Zhang
  • Berrin Tunca
  • Haiyan Min
  • Riccardo Di Fiore
  • SiHyun Cho
  • Li Hui Wu
  • Yu Xiang Yan
  • Boxing Su
  • Benjamin Boyerinas
  • Charn Jung Chang
  • Immacolata Andolfo
  • Yong Sun Lee
  • Iris Maria Forte
  • Shiyu Song
  • Hourong Cai
  • Anna De Blasio
  • Hui Li
  • Long Yi
  • Jinghong Dai
  • Renza Vento
  • Yi Zhuang
  • Antonio Giordano
  • Daniela Carlisi
  • Domenico Di Marzo
  • Yongzheng Wu
  • Giovanni Tesoriere
  • Qian Gao
  • Rosa Drago-Ferrante
  • Shanshan Fan
  • Francesca Pentimalli
  • Yu Tong Jin
  • Mei Yu
  • Min Peng
  • Hui Sun
  • Li Juan Wu
  • Shuo Wang
  • Yan He
  • Wei Wang
  • Xing Zhong Wu
  • Olga Grechukhina
  • Nian Hui Deng
  • Zhong Yi Chen
  • Qian Lei Zhao
  • Yong Jiang
  • Jie Zhang
  • Levent Mutlu
  • Hugh S Taylor
  • Chao Li
  • Jing Dong
  • Zhongqiang Guo
  • Wei Zhao
  • Bentao Shi
  • Xuesong Li
  • Feng Xie
  • Liqun Zhou
  • Jinghua Wang
  • Xi Yu
  • Qi Shen
  • Xiaoyu Zhang
  • Jin Liu
  • Marion Zillhardt
  • You Jia Hua
  • Ernst Lengyel
  • Sun Mi Park
  • Katja Gwin
  • Andrea E Murmann
  • Marcus E Peter
  • Anton G Montag
  • Lo Lin Tsai
  • Cuuan Hang Yu
  • Shao Wei Lu
  • Cheng Chia Yu
  • Ming Yung Chou
  • Chuan Chih Hsu
  • Chung Hung Tsai
  • Yu Chao Chang
  • Jhi Joung Wang
  • Fang Wei Hu
  • Hsu Shan Huang
  • Chin Hong Chang
  • Roberta Russo
  • Roberta Asci
  • Marisa Gorrese
  • Achille Iolascon
  • Luigia De Falco
  • Simona Colucci
  • Massimo Zollo
  • Anindya Dutta

Detail Information

Publications11

  1. pmc Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7
    Boxing Su
    Department of Urology, Peking University First Hospital and the Institute of Urology, Peking University, Beijing 100034, China
    Mol Cancer 13:206. 2014
    ..Here, we performed further analyses to determine whether let-7d is functionally linked to RCC malignancy...
  2. doi Circulating MicroRNA Let-7d in Attention-Deficit/Hyperactivity Disorder
    Li Hui Wu
    Department of Children s Health Care, Yuying Children s Hospital, Wenzhou Medical University, 109 West Xueyuan Road, Wenzhou, 325003, People s Republic of China
    Neuromolecular Med 17:137-46. 2015
    ..05) than those with high level of circulating miRNA let-7d. Our data demonstrated that miRNA let-7d was elevated in the serum of ADHD subjects, which might be a novel, useful molecule signature for ADHD...
  3. pmc Circulating microRNAs as potential biomarkers for endometriosis
    SiHyun Cho
    Department of Obstetrics and Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea
    Fertil Steril 103:1252-60.e1. 2015
    ..To evaluate whether microRNAs (miRNAs) associated with endometriosis are detectable in the circulation and could serve as potential noninvasive biomarkers for endometriosis...
  4. doi Let-7 related genetic variation and risk of metabolic syndrome in a Chinese population
    Yu Xiang Yan
    Department of Epidemiology and Biostatistics, School of Public Health, Capital Medical University, Beijing, China
    Endocr J 62:887-96. 2015
    ..In conclusion, our study found that let-7 related genetic variation is associated with MetS and may contribute to the susceptibility of MetS. Larger, prospective studies are warranted to validate our findings. ..
  5. doi Let-7d miRNA Shows Both Antioncogenic and Oncogenic Functions in Osteosarcoma-Derived 3AB-OS Cancer Stem Cells
    Riccardo Di Fiore
    Laboratory of Biochemistry, Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Polyclinic, Palermo, Italy
    J Cell Physiol 231:1832-41. 2016
    ..J. Cell. Physiol. 231: 1832-1841, 2016. © 2015 Wiley Periodicals, Inc. ..
  6. pmc Plasma microRNAs are associated with acute exacerbation in idiopathic pulmonary fibrosis
    Haiyan Min
    Department of Respiratory Medicine, Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University, Nanjing, China
    Diagn Pathol 11:135. 2016
    ..To predict this malignant condition in clinics is challenging. In this study, we aim to demonstrate whether there are miRNAs that differ between AE-IPF and stable IPF, which may be served as reliable biomarker for AE-IPF prediction...
  7. pmc Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1
    Benjamin Boyerinas
    Feinberg School of Medicine, Division Hematology Oncology, Northwestern University, Chicago, IL 60611, USA
    Int J Cancer 130:1787-97. 2012
    ..Our data point at IMP-1 and MDR1 as indicators for response to therapy, and at IMP-1 as a novel therapeutic target for overcoming multidrug resistance of ovarian cancer...
  8. doi Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer
    Charn Jung Chang
    Department of Pharmacy Practice, Tri Service General Hospital and National Defense Medical Center, Taipei, Taiwan, ROC
    Oncol Rep 26:1003-10. 2011
    ..In sum, these results show that let-7d negatively modulates EMT expression and also plays a role in regulating chemo-resistant ability in oral cancer...
  9. doi Olea europaea leaf extract alters microRNA expression in human glioblastoma cells
    Berrin Tunca
    Department of Medical Biology, Medical Faculty, Uludag University, Bursa, Turkey
    J Cancer Res Clin Oncol 138:1831-44. 2012
    ..The present study aimed to evaluate whether Olea europaea leaf extract (OLE) has an anticancer effect and modulates miRNA expression in GBM...
  10. pmc The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    Yong Sun Lee
    Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908, USA
    Genes Dev 21:1025-30. 2007
    ....
  11. pmc Regulation of divalent metal transporter 1 (DMT1) non-IRE isoform by the microRNA Let-7d in erythroid cells
    Immacolata Andolfo
    CEINGE, Biotecnologie Avanzate, Via, Comunale Margherita 482, 80145 Naples, Italy
    Haematologica 95:1244-52. 2010
    ..DMT1-IRE might be the major DMT1 isoform expressed in erythroid cells, although its regulation pathways are still unknown...