LSM12

Summary

Gene Symbol: LSM12
Description: LSM12 homolog
Alias: PNAS-135, protein LSM12 homolog
Species: human

Top Publications

  1. doi SH3RF2 functions as an oncogene by mediating PAK4 protein stability
    Tae Woo Kim
    Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305 806, Korea
    Carcinogenesis 35:624-34. 2014
  2. pmc Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks
    Aditi Singh
    Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ ZMBH Alliance, Im Neuenheimer Feld 282, D69120 Heidelberg, Germany
    Nucleic Acids Res 42:4652-68. 2014
  3. pmc Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate
    M Fittschen
    Experimental Neurology, Goethe University Medical School, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    Neurogenetics 16:181-92. 2015
  4. pmc Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes
    Tracey C Fleischer
    Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Genes Dev 20:1294-307. 2006
  5. pmc Pbp1 is involved in Ccr4- and Khd1-mediated regulation of cell growth through association with ribosomal proteins Rpl12a and Rpl12b
    Yuichi Kimura
    Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan
    Eukaryot Cell 12:864-74. 2013
  6. ncbi Novel Sm-like proteins with long C-terminal tails and associated methyltransferases
    Mario Albrecht
    Max Planck Institute for Informatics, Stuhlsatzenhausweg 85, 66123 Saarbrucken, Germany
    FEBS Lett 569:18-26. 2004
  7. pmc Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae
    Kylie D Swisher
    Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA
    PLoS ONE 5:e10006. 2010

Scientific Experts

  • Mario Albrecht
  • M Fittschen
  • Tae Woo Kim
  • Aditi Singh
  • Yuichi Kimura
  • Kylie D Swisher
  • Tracey C Fleischer
  • G Auburger
  • S Muller
  • E Damrath
  • M Walter
  • M Azizov
  • I Lastres-Becker
  • M V Halbach
  • S Gispert
  • Young Il Yeom
  • Su Jin Oh
  • Christine Clayton
  • Hyun Ahm Sohn
  • Dong Chul Lee
  • Esteban Erben
  • Ye Jin Jang
  • Eunhee Kim
  • Igor Minia
  • Seong Woo Hong
  • Se Yong Kim
  • Abeer Fadda
  • Kyung Chan Park
  • Hyang Sook Yoo
  • Zee Yong Park
  • Yun Kyung Kang
  • Suk Jin Yang
  • Dorothea Droll
  • Young Ho Kim
  • Kaoru Irie
  • Kenji Irie
  • Roy Parker
  • Andrew J Link
  • Connie M Weaver
  • Jennifer L Jennings
  • K Jill McAfee

Detail Information

Publications7

  1. doi SH3RF2 functions as an oncogene by mediating PAK4 protein stability
    Tae Woo Kim
    Medical Genomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305 806, Korea
    Carcinogenesis 35:624-34. 2014
    ..Taken together, our results suggest that SH3RF2 is an oncogene that may be a definitive regulator of PAK4. Therefore, SH3RF2 may represent an effective therapeutic target for cancer treatment...
  2. pmc Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks
    Aditi Singh
    Zentrum für Molekulare Biologie der Universität Heidelberg ZMBH, DKFZ ZMBH Alliance, Im Neuenheimer Feld 282, D69120 Heidelberg, Germany
    Nucleic Acids Res 42:4652-68. 2014
    ..PBP1 interacts with MKT1, LSM12 and poly(A) binding protein, and localizes to granules during parasite starvation...
  3. pmc Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate
    M Fittschen
    Experimental Neurology, Goethe University Medical School, Theodor Stern Kai 7, 60590, Frankfurt am Main, Germany
    Neurogenetics 16:181-92. 2015
    ..Prominent increases were observed for Lsm12/Paip1 (>2-fold), translation modulators known as protein interactor/competitor of ATXN2 and for Plin3/Mttp (>..
  4. pmc Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes
    Tracey C Fleischer
    Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    Genes Dev 20:1294-307. 2006
    ..Tandem affinity purification linked one candidate, LSM12, to the RNA processing proteins PBP1 and PBP4...
  5. pmc Pbp1 is involved in Ccr4- and Khd1-mediated regulation of cell growth through association with ribosomal proteins Rpl12a and Rpl12b
    Yuichi Kimura
    Department of Molecular Cell Biology, Graduate School of Comprehensive Human Sciences and Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan
    Eukaryot Cell 12:864-74. 2013
    ..Deletion of the gene encoding previously known Pbp1-interacting factor Lsm12, Pbp4, or Mkt1 did not suppress the growth defect of the ccr4Δ khd1Δ mutant, suggesting that Pbp1 acts ..
  6. ncbi Novel Sm-like proteins with long C-terminal tails and associated methyltransferases
    Mario Albrecht
    Max Planck Institute for Informatics, Stuhlsatzenhausweg 85, 66123 Saarbrucken, Germany
    FEBS Lett 569:18-26. 2004
    ..Using an integrative bioinformatics approach, we discovered five novel groups of Lsm domain proteins (Lsm12-16) with long C-terminal tails and investigated their functions...
  7. pmc Localization to, and effects of Pbp1, Pbp4, Lsm12, Dhh1, and Pab1 on stress granules in Saccharomyces cerevisiae
    Kylie D Swisher
    Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA
    PLoS ONE 5:e10006. 2010
    ..In Saccharomyces cerevisiae, Pbp1 also interacts with the Pab1, Lsm12, Pbp4, and Dhh1 proteins...