LRRC34

Summary

Gene Symbol: LRRC34
Description: leucine rich repeat containing 34
Alias: leucine-rich repeat-containing protein 34
Species: human

Top Publications

  1. pmc A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk
    Karen A Pooley
    Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care
    Hum Mol Genet 22:5056-64. 2013
  2. pmc Genome-wide association study identifies multiple loci associated with bladder cancer risk
    Jonine D Figueroa
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Hum Mol Genet 23:1387-98. 2014
  3. pmc Lrrc34, a novel nucleolar protein, interacts with npm1 and ncl and has an impact on pluripotent stem cells
    Sandra Lührig
    1 Institute of Human Genetics, University of Gottingen, Gottingen, Germany
    Stem Cells Dev 23:2862-74. 2014
  4. pmc Association between Genetic Variations Affecting Mean Telomere Length and the Prevalence of Hypertension and Coronary Heart Disease in Koreans
    Jean Kyung Paik
    Department of Food and Nutrition, Eulji University, Seongnam 13135, Korea
    Clin Nutr Res 5:249-260. 2016
  5. pmc Identification of novel markers of mouse fetal ovary development
    Huijun Chen
    Division of Molecular Genetics and Development, Institute for Molecular Biosciences, The University of Queensland, Brisbane, Australia
    PLoS ONE 7:e41683. 2012
  6. pmc Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
    Tasha E Fingerlin
    University of Colorado Denver, School of Public Health, Denver, Colorado, USA
    Nat Genet 45:613-20. 2013

Detail Information

Publications6

  1. pmc A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk
    Karen A Pooley
    Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care
    Hum Mol Genet 22:5056-64. 2013
    ..SNPs tagging these loci explain TL differences of up to 731 bp (corresponding to 18% of total TL in healthy individuals), however, they display little direct evidence for association with breast, ovarian or prostate cancer risks. ..
  2. pmc Genome-wide association study identifies multiple loci associated with bladder cancer risk
    Jonine D Figueroa
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Hum Mol Genet 23:1387-98. 2014
    ....
  3. pmc Lrrc34, a novel nucleolar protein, interacts with npm1 and ncl and has an impact on pluripotent stem cells
    Sandra Lührig
    1 Institute of Human Genetics, University of Gottingen, Gottingen, Germany
    Stem Cells Dev 23:2862-74. 2014
    The gene Lrrc34 (leucine rich repeat containing 34) is highly expressed in pluripotent stem cells and its expression is strongly downregulated upon differentiation...
  4. pmc Association between Genetic Variations Affecting Mean Telomere Length and the Prevalence of Hypertension and Coronary Heart Disease in Koreans
    Jean Kyung Paik
    Department of Food and Nutrition, Eulji University, Seongnam 13135, Korea
    Clin Nutr Res 5:249-260. 2016
    ..Among non-alcohol users, subjects with minor alleles in rs1269304 and rs10936601 (TERC and LRRC34, respectively) exhibited a higher rate of CHD occurrence (odds ratio [OR], 1...
  5. pmc Identification of novel markers of mouse fetal ovary development
    Huijun Chen
    Division of Molecular Genetics and Development, Institute for Molecular Biosciences, The University of Queensland, Brisbane, Australia
    PLoS ONE 7:e41683. 2012
    ..We were able to cluster these ovarian genes into different temporal expression categories. Of note, Lrrc34 and AK015184 were detected in XX but not XY germ cells before the onset of sex-specific germ cell differentiation ..
  6. pmc Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
    Tasha E Fingerlin
    University of Colorado Denver, School of Public Health, Denver, Colorado, USA
    Nat Genet 45:613-20. 2013
    ..Our results suggest that genes involved in host defense, cell-cell adhesion and DNA repair contribute to risk of fibrotic IIPs...