LPP

Summary

Gene Symbol: LPP
Description: LIM domain containing preferred translocation partner in lipoma
Alias: lipoma-preferred partner, LIM protein, lipoma preferred partner
Species: human

Top Publications

  1. ncbi Evaluation of inflammatory infiltrate and fibrogenic cytokines in pseudopelade of Brocq suggests the involvement of T-helper 2 and 3 cytokines
    S Moretti
    2nd Dermatology Clinic, Department of Dermatological Sciences, University of Florence, Azienda Sanitaria di Firenze, Via della Pergola 60, 50121 Florence, Italy
    Br J Dermatol 151:84-90. 2004
  2. doi Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions
    S Mihlan
    Institute of Clinical Biochemistry and Pathobiochemistry, University Clinic of Wuerzburg, Wuerzburg, Germany
    Oncogene 32:2107-13. 2013
  3. pmc Identification of cellular proteins required for replication of human immunodeficiency virus type 1
    Natallia Dziuba
    Department of Internal Medicine, University of Texas Medical Branch, Galveston, USA
    AIDS Res Hum Retroviruses 28:1329-39. 2012
  4. doi The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
    Daniel E Foxler
    School of Biomedical Sciences, University of Nottingham, Queen s Medical Centre, NG7 2UH, UK
    Nat Cell Biol 14:201-8. 2012
  5. ncbi LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family
    M M Petit
    Laboratory for Molecular Oncology, Center for Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology, Herestraat 49, Leuven, B 3000, Belgium
    Genomics 36:118-29. 1996
  6. ncbi Expression of reciprocal fusion transcripts of the HMGIC and LPP genes in parosteal lipoma
    M M Petit
    Laboratory for Molecular Oncology, University of Leuven, Belgium
    Cancer Genet Cytogenet 106:18-23. 1998
  7. pmc LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity
    M M Petit
    Laboratory for Molecular Oncology, Center for Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology, B 3000 Leuven, Belgium
    Mol Biol Cell 11:117-29. 2000
  8. ncbi The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein
    Marleen M R Petit
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven K U Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, Belgium
    J Biol Chem 278:2157-68. 2003
  9. ncbi LPP, a LIM protein highly expressed in smooth muscle
    Isabelle Gorenne
    Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908, USA
    Am J Physiol Cell Physiol 285:C674-85. 2003
  10. pmc Newly identified genetic risk variants for celiac disease related to the immune response
    Karen A Hunt
    Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, 4 Newark Street, London E1 2AT, UK
    Nat Genet 40:395-402. 2008

Research Grants

  1. Psychophysiology of Emotion in Parkinsons Disease
    JENNA B DIETZ; Fiscal Year: 2013
  2. Temporal Dynamics and Neural Bases of Emotion Regulation Under Emotional Load
    James J Gross; Fiscal Year: 2013
  3. Suppression of Negative Affect Indexed by the Late Positive Potential in Smokers
    JENNIFER ANNE MINNIX; Fiscal Year: 2010
  4. Emotion Regulation, Executive Function, and Parkinson Disease
    Dawn Bowers; Fiscal Year: 2013
  5. Susan S Smyth; Fiscal Year: 2014
  6. Characterization of new toxins (YmgD and YdfD) from E.coli, targeting cell wall
    Hisako Masuda; Fiscal Year: 2012
  7. Adonis K Hijaz; Fiscal Year: 2014
  8. Ashok K Chopra; Fiscal Year: 2015
  9. Teresa A Milner; Fiscal Year: 2016
  10. PPAR-gamma Signaling in Normal Pilosebaceous Units and in Scarring Alopecia
    Pratima Karnik; Fiscal Year: 2013

Patents

  1. Multiple-tumor aberrant growth genes
  2. MULTIPLE-TUMOR ABERRANT GROWTH GENES

Detail Information

Publications282 found, 100 shown here

  1. ncbi Evaluation of inflammatory infiltrate and fibrogenic cytokines in pseudopelade of Brocq suggests the involvement of T-helper 2 and 3 cytokines
    S Moretti
    2nd Dermatology Clinic, Department of Dermatological Sciences, University of Florence, Azienda Sanitaria di Firenze, Via della Pergola 60, 50121 Florence, Italy
    Br J Dermatol 151:84-90. 2004
    ..It may represent either a distinct entity, i.e. an idiopathic primary scarring alopecia, or the end stage of various forms of scarring alopecia such as discoid lupus erythematosus (DLE) or lichen planopilaris (LPP).
  2. doi Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein-protein interactions
    S Mihlan
    Institute of Clinical Biochemistry and Pathobiochemistry, University Clinic of Wuerzburg, Wuerzburg, Germany
    Oncogene 32:2107-13. 2013
    ..Finally, dephosphorylation of LASP-1 by phosphatase PP2B is suggested to relocalize the protein back to focal contacts. In summary, we define a new pathway for LASP-1 in tumor progression...
  3. pmc Identification of cellular proteins required for replication of human immunodeficiency virus type 1
    Natallia Dziuba
    Department of Internal Medicine, University of Texas Medical Branch, Galveston, USA
    AIDS Res Hum Retroviruses 28:1329-39. 2012
    ..However, the genes presented in this study did not share identity with those found previously. Novel antiviral targets identified in this study should open new avenues for mechanistic investigation...
  4. doi The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
    Daniel E Foxler
    School of Biomedical Sciences, University of Nottingham, Queen s Medical Centre, NG7 2UH, UK
    Nat Cell Biol 14:201-8. 2012
    ..LIMD1 family member proteins Ajuba and WTIP also bind to VHL and PHDs 1 and 3, indicating that these LIM domain-containing proteins represent a previously unrecognized group of hypoxic regulators...
  5. ncbi LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family
    M M Petit
    Laboratory for Molecular Oncology, Center for Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology, Herestraat 49, Leuven, B 3000, Belgium
    Genomics 36:118-29. 1996
    ..characterization of the chromosome 3-derived translocation partner gene, which we have designated LPP (lipoma preferred partner gene)...
  6. ncbi Expression of reciprocal fusion transcripts of the HMGIC and LPP genes in parosteal lipoma
    M M Petit
    Laboratory for Molecular Oncology, University of Leuven, Belgium
    Cancer Genet Cytogenet 106:18-23. 1998
    ..Recently, we established that the genes HMGIC at 12q15 and LPP at 3q27-28 are affected by the 3;12-translocation and demonstrated that, as a direct result, HMGIC/LPP and LPP/..
  7. pmc LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity
    M M Petit
    Laboratory for Molecular Oncology, Center for Human Genetics, University of Leuven and Flanders Interuniversity Institute for Biotechnology, B 3000 Leuven, Belgium
    Mol Biol Cell 11:117-29. 2000
    The LPP gene is the preferred translocation partner of the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas...
  8. ncbi The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein
    Marleen M R Petit
    Laboratory for Molecular Oncology, Department of Human Genetics, University of Leuven K U Leuven and Flanders Interuniversity Institute for Biotechnology VIB, Herestraat 49, Belgium
    J Biol Chem 278:2157-68. 2003
    Targeting of proteins to a particular cellular compartment is a critical determinant for proper functioning. LPP (LIM-containing lipoma-preferred partner) is a LIM domain protein that is localized at sites of cell adhesion and ..
  9. ncbi LPP, a LIM protein highly expressed in smooth muscle
    Isabelle Gorenne
    Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908, USA
    Am J Physiol Cell Physiol 285:C674-85. 2003
    An 80-kDa protein, prominently expressed in smooth muscle, was microsequenced and identified as LPP, the product of the lipoma-preferred partner gene (Petit MMR, Mols R, Schoenmakers EFPM, Mandahl N, and Van de Ven WJM...
  10. pmc Newly identified genetic risk variants for celiac disease related to the immune response
    Karen A Hunt
    Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, 4 Newark Street, London E1 2AT, UK
    Nat Genet 40:395-402. 2008
    ..Type 1 diabetes and celiac disease share HLA-DQ, IL2-IL21, CCR3 and SH2B3 risk regions. Thus, this extensive genome-wide association follow-up study has identified additional celiac disease risk variants in relevant biological pathways...
  11. pmc Shared and distinct genetic variants in type 1 diabetes and celiac disease
    Deborah J Smyth
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    N Engl J Med 359:2767-77. 2008
    ..Since both diseases are associated with the HLA class II genes on chromosome 6p21, we tested whether non-HLA loci are shared...
  12. pmc Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP
    Thomas Gp Grunewald
    Department of Pediatrics, Klinikum rechts der Isar, Technische Universitat Munchen, Pediatric Oncology Center, Kolner Platz 1, D 80804 Munich, Germany
    Transl Oncol 2:107-16. 2009
    ..Among them, the most prominent representatives are zyxin and lipoma preferred (translocation) partner (LPP)...
  13. pmc Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo
    Ying Jin
    Human Medical Genetics Program, School of Medicine, University of Colorado, P O Box 6511, Mailstop 8300, Aurora, CO 80045, USA
    N Engl J Med 362:1686-97. 2010
    ..Generalized vitiligo is an autoimmune disease characterized by melanocyte loss, which results in patchy depigmentation of skin and hair, and is associated with an elevated risk of other autoimmune diseases...
  14. ncbi The lipoma preferred partner LPP interacts with alpha-actinin
    Bo Li
    ITI Research Institute, University of Bern, PO Box 54, CH 3010 Bern, Switzerland
    J Cell Sci 116:1359-66. 2003
    The lipoma preferred partner LPP is a member of the zyxin family of proteins. In this paper, we demonstrate that the structural similarities observed between zyxin and LPP also extend to their interaction capabilities...
  15. pmc Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis
    Anne Hinks
    Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, Stopford Building, The University of Manchester, Manchester, UK
    Ann Rheum Dis 69:2169-72. 2010
    ..There is strong evidence suggesting that juvenile idiopathic arthritis (JIA) shares many susceptibility loci with other autoimmune diseases...
  16. ncbi Human LPP gene is fused to MLL in a secondary acute leukemia with a t(3;11) (q28;q23)
    L Daheron
    Laboratoire d Hématologie CNRS FRE 2224, Poitiers University Hospital, CHU La Miletrie BP577, 86021 Poitiers Cedex, France
    Genes Chromosomes Cancer 31:382-9. 2001
    ..Through inverse PCR, the LPP (lipoma preferred partner) gene on 3q28 was identified as the MLL fusion partner...
  17. ncbi Mifepristone (RU486) inhibits lateral perforant path long-term potentiation in hippocampal slices from prenatally morphine-exposed female rats
    LIBOR VELISEK
    Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA
    Int J Dev Neurosci 23:559-65. 2005
    ..rats during proestrus and diestrus, long-term potentiation (LTP) can be induced in the lateral perforant pathway (LPP). Prenatal morphine exposure suppresses LTP induction in the LPP during proestrus...
  18. doi Reduction of four-and-a-half LIM-protein 2 expression occurs in human left ventricular failure and leads to altered localization and reduced activity of metabolic enzymes
    Esta Bovill
    Department of Medicine, University College London, London, United Kingdom
    J Thorac Cardiovasc Surg 137:853-61. 2009
    ....
  19. ncbi Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assembly
    Meagan J McGrath
    Department of Biochemistry and Molecular Biology, Monash University, Wellington Road, Clayton, Victoria 3800, Australia
    J Biol Chem 281:7666-83. 2006
    Four and a half LIM protein 1 (FHL1/SLIM1) is highly expressed in skeletal and cardiac muscle; however, the function of FHL1 remains unknown...
  20. doi High association of human herpesvirus 8 in large-plaque parapsoriasis and mycosis fungoides
    Alexander Kreuter
    Department of Dermatology, Ruhr University Bochum, Gudrunstrasse 56, D 44791 Bochum, Germany
    Arch Dermatol 144:1011-6. 2008
    ..the presence of human herpesvirus 8 (HHV-8) in lesional skin of German patients with large-plaque parapsoriasis (LPP) or mycosis fungoides (MF). The pathogenetic relevance of HHV-8 in cutaneous T-cell lymphoma is controversial...
  21. ncbi Plastidic phosphatidic acid phosphatases identified in a distinct subfamily of lipid phosphate phosphatases with prokaryotic origin
    Yuki Nakamura
    Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 B 65 Nagatsuta cho, Midori ku, Yokohama 226 8501, Japan
    J Biol Chem 282:29013-21. 2007
    ..and characterization of plastidic PAPs in Arabidopsis that belong to a distinct lipid phosphate phosphatase (LPP) subfamily with prokaryotic origin...
  22. pmc Immunological responses against Salmonella enterica serovar Typhimurium Braun lipoprotein and lipid A mutant strains in Swiss-Webster mice: potential use as live-attenuated vaccines
    Tie Liu
    Department of Microbiology and Immunology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 775551070, USA
    Microb Pathog 44:224-37. 2008
    ..Salmonella enterica serovar Typhimurium mutants that were deleted for the genes encoding Braun lipoprotein (lpp) alone or in conjunction with the msbB gene, which codes for an enzyme required for the acylation of the lipid A ..
  23. ncbi Molecular characterization of a PDZ-LIM protein in Atlantic salmon (Salmo salar): a fish ortholog of the alpha-actinin-associated LIM-protein (ALP)
    Øivind Andersen
    Institute of Aquaculture Research, P O Box 5010, N 1432 Aas, Norway
    J Muscle Res Cell Motil 25:61-8. 2004
    A protein containing both PDZ and LIM protein-protein interaction motifs has for the first time been identified in a lower vertebrate species...
  24. ncbi Actin/alpha-actinin-dependent transport of AMPA receptors in dendritic spines: role of the PDZ-LIM protein RIL
    Torsten W Schulz
    Max Planck Institute for Medical Research, Department of Molecular Neurobiology, 69120 Heidelberg, Germany
    J Neurosci 24:8584-94. 2004
    ..suppressor zona occludens 1) and LIM (Lin11/rat Isl-1/Mec3) domain-containing protein, RIL (reversion-induced LIM protein)...
  25. ncbi Dystrophin- and MLP-deficient mouse hearts: marked differences in morphology and function, but similar accumulation of cytoskeletal proteins
    James R Wilding
    Department of Physiology, University of Oxford, Oxford, England, UK
    FASEB J 19:79-81. 2005
    In humans, cytoskeletal dystrophin and muscle LIM protein (MLP) gene mutations can cause dilated cardiomyopathy, yet these mutations may have different effects in mice, owing to increased accumulation of other, compensatory cytoskeletal ..
  26. ncbi Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats
    Yasuhiro Kaiho
    Dept of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Physiol Renal Physiol 292:F639-46. 2007
    ..sneezing (A-URS), urethral baseline pressure (UBP) at the midurethra, and sneeze-induced leak point pressure (S-LPP) were measured in normal female adult rats and rats with SUI induced by vaginal distention (VD)...
  27. ncbi Interaction of short-term neuronal plasticity and synaptic plasticity revealed by nonlinear systems analysis in dentate granule cells
    Xiaping Xie
    Center for Neural Engineering, University of Southern California, Los Angeles, CA 90089, USA
    Conf Proc IEEE Eng Med Biol Soc 1:5543-6. 2006
    ..There are two components of the perforant path: the lateral component (LPP) and the medial component (MPP). LPP and MPP convey different sensory modality information...
  28. pmc Poly(A) RNA in Escherichia coli: nucleotide sequence at the junction of the lpp transcript and the polyadenylate moiety
    G J Cao
    Department of Metabolic Regulation, Boston Biomedical Research Institute, MA 02114
    Proc Natl Acad Sci U S A 89:7546-50. 1992
    ..in exoribonucleases and synthesized DNA complementary to polyadenylylated lipoprotein mRNA, encoded by the lpp gene, by using avian myeloblastosis virus reverse transcriptase and an oligo(dT)-containing primer...
  29. ncbi Prenatal morphine exposure suppresses mineralocorticoid receptor-dependent basal synaptic transmission and synaptic plasticity in the lateral perforant path in adult male rats
    LIBOR VELISEK
    Department of Neurology, Albert Einstein College of Medicine, K 314, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Brain Res Bull 61:571-6. 2003
    ..mineralocorticoid receptor (MR) modulation of synaptic plasticity were investigated in the lateral perforant path (LPP)-dentate gyrus granule cell synaptic system...
  30. pmc Effect of duloxetine, a norepinephrine and serotonin reuptake inhibitor, on sneeze-induced urethral continence reflex in rats
    Minoru Miyazato
    Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Physiol Renal Physiol 295:F264-71. 2008
    ..sneezing (A-URS), urethral baseline pressure (UBP) at the midurethra, and sneeze-induced leak point pressure (S-LPP) were measured in normal adult female rats and rats with SUI induced by vaginal distension (VD)...
  31. ncbi [The assessment of the mental state of patients during simultaneous treatment with psychotropic drugs, antipsychotics included, and bromocriptine]
    Zbigniew Barszcz
    Centralny Szpital Kliniczny UM w Lodzi
    Psychiatr Pol 42:595-607. 2008
    ..The aim of this study was to assess the mental state of patients treated with psychotropic drugs (LPT) and bromocriptine (BRC) at the same time...
  32. ncbi Age-related changes in the metabolization of phosphatidic acid in rat cerebral cortex synaptosomes
    S J Pasquare
    Instituto de Investigaciones Bioquímicas de Bahía Blanca INIBIBB, Universidad Nacional del Sur and Consejo Nacional de Investigaciones Científicas y Técnicas CONICET, C C 857, B8000FWB Bahia Blanca, Argentina
    Arch Biochem Biophys 488:121-9. 2009
    ..diacylglycerol (DAG), monoacylglycerol (MAG) and glycerol by the sequential action of lipid phosphate phosphatase (LPP), diacylglycerol lipase (DAGL), and monoacylglycerol lipase (MAGL) in cerebral cortex (CC) synaptosomes...
  33. ncbi Lichen planus pemphigoides is a heterogeneous disease: a report of five cases studied by immunoelectron microscopy
    A Bouloc
    Department of Dermatology, Hopital Saint Louis, Paris, France
    Br J Dermatol 138:972-80. 1998
    Lichen planus pemphigoides (LPP) is a rare and controversial disease...
  34. ncbi The PDZ-LIM protein RIL modulates actin stress fiber turnover and enhances the association of alpha-actinin with F-actin
    Tea Vallenius
    Molecular Cancer Biology Program, Institute of Biomedicine and Helsinki University Central Hospital, University of Helsinki, Biomedicum Helsinki, Finland
    Exp Cell Res 293:117-28. 2004
    ..These results implicate the RIL PDZ-LIM protein as a regulator of actin stress fiber turnover.
  35. doi Multiple alternative splicing and differential expression of actinin-associated LIM protein (ALP) during porcine skeletal muscle development in vitro and in vivo
    Linjie Wang
    Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture, College of Animal Science, Huazhong Agricultural University, Wuhan, Hubei 430070, PR China
    Meat Sci 84:655-61. 2010
    The actinin-associated LIM protein (ALP) is co-localized with alpha-actinin at the Z-discs and plays a critical role in the integration of cytoskeletal architecture and transcriptional regulation...
  36. pmc Actinin-associated LIM protein-deficient mice maintain normal development and structure of skeletal muscle
    K Jo
    Department of Physiology, University of California at San Francisco, San Francisco, California 94143, USA
    Mol Cell Biol 21:1682-7. 2001
    The actinin-associated LIM protein, ALP, is the prototype of a large family of proteins containing an N-terminal PDZ domain and a C-terminal LIM domain...
  37. pmc Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1
    Kyungmin Hahm
    Division of Hematology Oncology, Department of Pediatrics, Children s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    Mol Cell Biol 24:2074-82. 2004
    ..Our data indicate an important role for these two transcriptional regulators in pathways affecting neural tube closure and skeletal patterning, most likely reflecting their presence in a functional complex in vivo...
  38. pmc Distribution of newly synthesized lipoprotein over the outer membrane and the peptidoglycan sacculus of an Escherichia coli lac-lpp strain
    H Hiemstra
    Department of Biochemistry, University of Groningen, The Netherlands
    J Bacteriol 169:5434-44. 1987
    ..Lipoprotein was briefly induced with isopropyl-beta-D-thiogalactopyranoside in cells carrying lac-lpp on a low-copy-number plasmid in an E. coli lpp host...
  39. pmc Identification and characterization of thymus LIM protein: targeted disruption reduces thymus cellularity
    J Kirchner
    Howard Hughes Medical Institute and Department of Immunology, University of Washington, Seattle, WA 98195, USA
    Mol Cell Biol 21:8592-604. 2001
    We have identified a novel LIM gene encoding the thymus LIM protein (TLP), expressed specifically in the thymus in a subset of cortical epithelial cells...
  40. ncbi Long-term vision results measured with Teller Acuity Cards and a new Light Perception/Projection Scale after management of late stages of retinopathy of prematurity
    M Elizabeth Hartnett
    Department of Ophthalmology, University of North Carolina, Chapel Hill 27599 7040, USA
    Arch Ophthalmol 121:991-6. 2003
    To report visual acuity (VA) measured by Teller Acuity Cards (TACs) and a new Light Perception/Projection (LPP) Scale in infants with regressed or treated stage 3, 4, or 5 retinopathy of prematurity (ROP), and to compare VA in eyes that ..
  41. doi 18F-dihydroxyphenylalanine PET in patients with biochemical evidence of medullary thyroid cancer: relation to tumor differentiation
    Klaas P Koopmans
    Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands
    J Nucl Med 49:524-31. 2008
    ..Therefore, the value of 18F-dihydroxyphenylalanine PET (18F-DOPA PET), 18F-FDG PET, (99m)Tc-V-di-mercaptosulfuricacid (DMSA-V) scintigraphy, and MRI or CT was studied...
  42. pmc Deletion of Braun lipoprotein gene (lpp) and curing of plasmid pPCP1 dramatically alter the virulence of Yersinia pestis CO92 in a mouse model of pneumonic plague
    Stacy L Agar
    Department of Microbiology and Immunology, University of Texas Medical Branch UTMB, Galveston, TX, USA
    Microbiology 155:3247-59. 2009
    Deletion of the murein (Braun) lipoprotein gene, lpp, attenuates the Yersinia pestis CO92 strain in mouse models of bubonic and pneumonic plague...
  43. pmc Quantitative evaluation of electrodes for external urethral sphincter electromyography during bladder-to-urethral guarding reflex
    James E Steward
    Department of Biomedical Engineering, Cleveland Clinic, 9500 Euclid Ave ND20, Cleveland, OH, 44195, USA
    World J Urol 28:365-71. 2010
    ..The aim of this study was to quantitatively compare electrode recordings taken during tonic activity and leak point pressure (LPP) testing.
  44. pmc Role of spinal serotonergic pathways in sneeze-induced urethral continence reflex in rats
    Minoru Miyazato
    Dept of Urology, Univ of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Am J Physiol Renal Physiol 297:F1024-31. 2009
    ..sneezing (A-URS), urethral baseline pressure (UBP) at the midurethra, and sneeze-induced leak point pressure (S-LPP) were measured in normal female adult rats and rats with SUI induced by vaginal distention (VD)...
  45. ncbi Cicatricial pemphigoid differs from bullous pemphigoid and pemphigoid gestationis regarding the fine specificity of autoantibodies to the BP180 NC16A domain
    Arno Kromminga
    Institute for Immunology, Clinical Pathology and Molecular Medicine IPM, Hamburg, Germany
    J Dermatol Sci 28:68-75. 2002
    ..pemphigoid (BP), pemphigoid (herpes) gestationis (PG), cicatricial pemphigoid (CP), and lichen planus pemphigoides (LPP) are autoimmune subepidermal bullous diseases that are characterized by circulating autoantibodies to the ..
  46. ncbi Modulation of lateral perforant path excitatory responses by metabotropic glutamate 8 (mGlu8) receptors
    Jin Zhai
    Neuroscience Division, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Neuropharmacology 43:223-30. 2002
    ..of metabotropic glutamate 8 (mGlu8) receptors to modulation of medial and lateral perforant path (MPP and LPP) inputs to the dentate gyrus was investigated using electrophysiological recording of field excitatory postsynaptic ..
  47. doi The conundrum of parapsoriasis versus patch stage of mycosis fungoides
    K N Sarveswari
    Sundaram Medical Foundation, Dr Rangarajan Memorial Hospital, Chennai, Tamilnadu, India
    Indian J Dermatol Venereol Leprol 75:229-35. 2009
    ..Some believe that large plaque parapsoriasis (LPP) should be classified with early patch stage of MF and should be treated aggressively...
  48. ncbi Lichen planus pemphigoides evolving into pemphigoid nodularis
    Y Sakuma-Oyama
    Department of Dermato immunopathology, St John s Institute of Dermatology, Guy s, King s and St Thomas School of Medicine, St Thomas Hospital KCL, London, UK
    Clin Exp Dermatol 28:613-6. 2003
    Lichen planus pemphigoides (LPP) and pemphigoid nodularis are rare clinical variants of bullous pemphigoid (BP), which are characterized by histological findings of lichen planus (LP) and nodular prurigo, respectively, and the finding of ..
  49. ncbi Molecular cloning, characterization, and promoter analysis of the mouse Crp2/SmLim gene. Preferential expression of its promoter in the vascular smooth muscle cells of transgenic mice
    S F Yet
    Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Biol Chem 273:10530-7. 1998
    Several members of the LIM protein family have important roles in development and differentiation...
  50. ncbi Medial perforant path inhibition mediated by mGluR7 is reduced after status epilepticus
    Kristopher J Bough
    School of Medicine, Dept of Pharmacology, Emory University, Rollins Research Center, Rm 5002, 1510 Clifton Road, Atlanta, GA 30322 3090, USA
    J Neurophysiol 92:1549-57. 2004
    ..Field excitatory postsynaptic potentials (fEPSPs) were recorded in the lateral (LPP) and medial perforant path (MPP) simultaneously in adult mouse hippocampal slices 3-9 days after pilocarpine (PILO)-..
  51. doi Autologous bone-marrow-derived mesenchymal stem cell transplantation into injured rat urethral sphincter
    Yoshiaki Kinebuchi
    Department of Urology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan
    Int J Urol 17:359-68. 2010
    ..To evaluate the functional and histological recovery by autologous bone-marrow-derived mesenchymal stem cell (BMSC) transplantation into injured rat urethral sphincters...
  52. ncbi Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1. Localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and cytoplasm of myotubes suggests distinct roles in the cytoskeleton and in nuclear
    S Brown
    Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia 3168
    J Biol Chem 274:27083-91. 1999
    We have cloned and characterized a novel isoform of the skeletal muscle LIM protein 1 (SLIM1), designated SLIMMER. SLIM1 contains an N-terminal single zinc finger followed by four LIM domains...
  53. pmc Normal kidney size and its influencing factors - a 64-slice MDCT study of 1.040 asymptomatic patients
    Bernhard Glodny
    Department of Radiology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    BMC Urol 9:19. 2009
    Normal ultrasound values for pole-to-pole kidney length (LPP) are well established for children, but very little is known about normal kidney size and its influencing factors in adults...
  54. doi Lmcd1/Dyxin, a novel Z-disc associated LIM protein, mediates cardiac hypertrophy in vitro and in vivo
    Derk Frank
    Department of Internal Medicine III, University of Heidelberg, Heidelberg, Germany
    J Mol Cell Cardiol 49:673-82. 2010
    ..In addition to known members of the hypertrophic gene program, we found the novel sarcomeric Z-disc LIM protein Lmcd1/Dyxin markedly upregulated...
  55. pmc Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein
    D J Roof
    Berman Gund Laboratory for the Study of Retinal Degenerations, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Cell Biol 138:575-88. 1997
    ..that abLIM may play a general role in bridging the actin-based cytoskeleton with an array of potential LIM protein-binding partners...
  56. ncbi The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba
    Helene Marie
    Department of Physiology, Laboratory of Molecular Cell Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom
    Mol Cell Neurosci 19:152-64. 2002
    We have identified a cytoplasmic LIM protein, Ajuba, which interacts with the amino terminus of GLT-1, the most abundant plasma membrane glutamate transporter in the brain...
  57. pmc The human and mouse orthologous LIM-only proteins respectively encoded in chromosome 6 and 17 show a different expression pattern
    Armanda Casrouge
    Laboratoire de Biologie Moléculaire du Gène, Inserm U277 Institut Pasteur, 75724 Paris Cedex 15, France
    Microbes Infect 6:1063-72. 2004
    ..We identified a LIM protein located on mouse chromosome 17 (m17TLP) and belonging to the family of the LIM-only proteins (LIMo)...
  58. ncbi Uni-axial stretching regulates intracellular localization of Hic-5 expressed in smooth-muscle cells in vivo
    Joo ri Kim-Kaneyama
    Department of Microbiology, Showa University School of Pharmaceutical Sciences, 1 5 8 Hatanodai, Shinagawa ku, Tokyo 142 8555, Japan
    J Cell Sci 118:937-49. 2005
    ..Of the factors tested, which included interacting partners of Hic-5, only CRP2 (an only-LIM protein expressed in vascular smooth-muscle cells) and GIT1 were, like Hic-5, localized to stress fibers during the ..
  59. ncbi Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy
    Takuro Arimura
    Department of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 101 0062, Japan
    Biochem Biophys Res Commun 357:162-7. 2007
    ..To explore a novel disease gene for DCM, we searched for mutations in FHL2, encoding for four and half LIM protein 2 (FHL2) in DCM patients, because FHL2 is known to associate with titin/connectin...
  60. doi PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling
    Dongtak Jeong
    Global Research Laboratory and Department of Life Science, Gwangju Institute of Science and Technology, Gwangju, Korea
    Circ Res 102:711-9. 2008
    ..pull-down experiments and mass spectrometry enabled us to determine that PICOT directly interacts with muscle LIM protein (MLP) via its carboxyl-terminal half (PICOT-C). It was also shown that PICOT colocalizes with MLP in the Z-disc...
  61. doi Physiological effects of human muscle-derived stem cell implantation on urethral smooth muscle function
    Akira Furuta
    Department of Urology, University of Pittsburgh School of Medicine, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    Int Urogynecol J Pelvic Floor Dysfunct 19:1229-34. 2008
    ..Leak point pressure (LPP) before and after hexamethonium application, which can block autonomic efferent nerves, and proximal urethral ..
  62. doi The four-and-a-half-LIM protein 2 (FHL2) is overexpressed in gliomas and associated with oncogenic activities
    Ming Li
    Department of Chemistry, Open Laboratory of Chemical Biology, University of Hong Kong, Hong Kong, People s Republic of China
    Glia 56:1328-38. 2008
    Four-and-a-half-LIM protein 2 (FHL2) is a member of FHL protein family, which plays a crucial role in regulating gene expression, cell survival, and migration...
  63. doi Neurocognitive mechanisms underlying identification of environmental risks
    Jungang Qin
    Department of Psychology, Peking University, Beijing 100871, People s Republic of China
    Neuropsychologia 47:397-405. 2009
    ..at 180-260ms over the frontal area (P200) and of a late positive wave at 420-660ms over the central-parietal area (LPP)...
  64. doi Long periodicity phase in extracted lipids of vernix caseosa obtained with equilibration at physiological temperature
    Robert Rissmann
    Leiden Amsterdam Center for Drug Research, Department of Drug Delivery Technology, P O Box 9502, 2300 RA Leiden, The Netherlands
    Chem Phys Lipids 158:32-8. 2009
    ..The SC features a highly structured lipid organization: a short periodicity phase and a long periodicity phase (LPP) with a repeat distance of 6 and 13 nm, respectively...
  65. doi Suture-free laser-assisted vessel repair using CO2 laser and liquid albumin solder
    Ingrid C D Y M Wolf-de Jonge
    Academic Medical Center, Department of Vascular Surgery, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    J Biomed Opt 13:044032. 2008
    ..The LPP of the two-pass welds was 351+/-158 mmHg versus 538+/-155 mmHg for the three-pass welds...
  66. pmc Myocyte remodeling in response to hypertrophic stimuli requires nucleocytoplasmic shuttling of muscle LIM protein
    Samuel Y Boateng
    Department of Physiology and Biophysics M C 901, University of Illinois at Chicago, 835 South Wolcott Avenue, Chicago, IL 60612 7342, USA
    J Mol Cell Cardiol 47:426-35. 2009
    CSRP3 or muscle LIM protein (MLP) is a nucleocytoplasmic shuttling protein and a mechanosensor in cardiac myocytes...
  67. doi Surface plasmon resonance analysis of the binding of high-risk mucosal HPV E6 oncoproteins to the PDZ1 domain of the tight junction protein MAGI-1
    Sadek Fournane
    Equipe Oncoprotéines, FRE 3211, Institut de Recherche de l Ecole de Biotechnologie de Strasbourg, Universite de Strasbourg, Boulevard Sebastien Brandt, BP 10413, 67412 Illkirch Cedex, France
    J Mol Recognit 24:511-23. 2011
    ..Finally, we showed that MAGI-1 PDZ1 also binds to the C-termini of LPP and Tax proteins, which were already known to bind to PDZ proteins but not to MAGI-1.
  68. doi Degradation of pentachlorophenol and 2,4-dichlorophenol by sequential visible-light driven photocatalysis and laccase catalysis
    Lifeng Yin
    State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, PR China
    Environ Sci Technol 44:9117-22. 2010
    ..prior to laccase-catalysis (PPL) is a better approach than laccase-catalysis prior to photocatalysis (LPP), eliminating CPs more efficiently and generating lower toxic products...
  69. doi Effects of recent word exposure on emotion-word Stroop interference: an ERP study
    Liselotte Gootjes
    Erasmus Affective Neuroscience Lab, Institute of Psychology, Erasmus University Rotterdam, Rotterdam, The Netherlands
    Int J Psychophysiol 79:356-63. 2011
    ..At the neurophysiological level, we found more positive-going ERPs at later latencies (P290, N400 and LPP) in response to negative than in response to neutral Stroop words...
  70. pmc Source localization of late electrocortical positivity during symptom provocation in spider phobia: an sLORETA study
    Wilfried Scharmüller
    Department of Clinical Psychology, Institute of Psychology, University of Graz, Austria
    Brain Res 1397:10-8. 2011
    ..amplitudes of ERPs were extracted in the time windows 340-500 ms (P300) and 550-770 ms (late positive potential, LPP). Phobics showed enhanced P300 and LPP amplitudes in response to spider pictures relative to controls...
  71. doi A zyxin-nectin interaction facilitates zyxin localization to cell-cell adhesions
    S Gregory Call
    Physiology and Developmental Biology, Brigham Young University, 574 WIDB, Provo, UT 84602, United States
    Biochem Biophys Res Commun 415:485-9. 2011
    ..been implicated in actin remodeling events as cell-cell contacts are assembled and disassembled, including zyxin/LPP-VASP complexes. These complexes facilitate strong cell-cell adhesion by maintaining actin-membrane connections...
  72. pmc Electrocortical reactivity to emotional images and faces in middle childhood to early adolescence
    Autumn Kujawa
    Department of Psychology, Stony Brook University, Stony Brook, NY 11794 2500, United States
    Dev Cogn Neurosci 2:458-67. 2012
    The late positive potential (LPP) is an event-related potential (ERP) component that indexes sustained attention toward motivationally salient information...
  73. pmc A LIM domain protein from tobacco involved in actin-bundling and histone gene transcription
    Danièle Moes
    Centre de Recherche Public Santé, 84, Val Fleuri, L 1526 Luxembourg, Luxembourg
    Mol Plant 6:483-502. 2013
    ..factors that bind to plant histone gene promoters, we isolated a positive clone containing the tobacco LIM protein WLIM2 (NtWLIM2) cDNA...
  74. doi Fearful faces grab attention in the absence of late affective cortical responses
    Koki Ikeda
    Department of Cognitive and Behavioral Sciences, The University of Tokyo, Tokyo, Japan
    Psychophysiology 50:60-9. 2013
    ..attentional capture occurred even under high task load, by which the late cortical affective activity (the LPP modulation) was entirely suppressed...
  75. doi Danger and disease: electrocortical responses to threat- and disgust-eliciting images
    Michael G Wheaton
    Department of Psychiatry, University of Illinois at Chicago, United States
    Int J Psychophysiol 90:235-9. 2013
    ..event-related potentials (ERPs), including the early posterior negativity (EPN) and late positive potential (LPP)...
  76. pmc The serum resistome of a globally disseminated multidrug resistant uropathogenic Escherichia coli clone
    Minh Duy Phan
    Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Queensland, Australia School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia
    PLoS Genet 9:e1003834. 2013
    ..Targeted mutagenesis confirmed a role in serum resistance for 46 (82%) of these genes. The murein lipoprotein Lpp, along with two lipid A-core biosynthesis enzymes WaaP and WaaG, were most strongly associated with serum ..
  77. doi Emotional scenes elicit more pronounced self-reported emotional experience and greater EPN and LPP modulation when compared to emotional faces
    Nathaniel Thom
    Department of Applied Health Science, Wheaton College, Wheaton, IL, 60187, USA
    Cogn Affect Behav Neurosci 14:849-60. 2014
    ..g., N170, early posterior negativity [EPN], late positive potential [LPP]) as subjects viewed neutral and emotional faces and scenes, including contents representing anger, fear, and joy...
  78. doi Attractiveness and affordance shape tools neural coding: insight from ERPs
    Stefania Righi
    Psychology Section, Department of Neuroscience, Psychology, Drug Research and Child s Health, University of Florence, Italy Electronic address
    Int J Psychophysiol 91:240-53. 2014
    ..The N300, P300 and the Late Positive Potential (LPP) showed enhanced responses for highly affording/attractive tools, reflecting the interconnection between ..
  79. doi Emotional content of stimuli improves visuospatial working memory
    Andrés Antonio González-Garrido
    Instituto de Neurociencias, Universidad de Guadalajara, Mexico O P D Hospital Civil de Guadalajara, Mexico Electronic address
    Neurosci Lett 585:43-7. 2015
    ..In addition, LPP amplitude was also significantly higher for this type of stimuli...
  80. pmc Specific electrophysiological components disentangle affective sharing and empathic concern in psychopathy
    Jean Decety
    Child Neurosuite, Department of Psychology, The University of Chicago, Chicago, Illinois and Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, Illinois
    J Neurophysiol 114:493-504. 2015
    ..Results indicate that early automatic (175-275 ms) and later controlled responses (LPP 400-1,000 ms) were differentially modulated by engagement in affective sharing or empathic concern...
  81. doi Implicit emotion regulation in the context of viewing artworks: ERP evidence in response to pleasant and unpleasant pictures
    Noah N N Van Dongen
    Erasmus School of History, Culture and Communication, Erasmus University Rotterdam, Rotterdam, Netherlands
    Brain Cogn 107:48-54. 2016
    ..of staged scenes" or "photographs depicting real events" modulated perceivers' Late Positive Potentials (LPP) and likability ratings...
  82. ncbi Effects of harmonics on aesthetic judgments of music: an ERP study involving laypersons and experts
    Marta Jaśkiewicz
    The John Paul II Catholic University of Lublin, Lublin, Poland
    Acta Neurobiol Exp (Wars) 76:142-51. 2016
    ..S. Bach's chorales. Experts and laypersons showed different late positive potential (LPP) responses to the appraisal of correctness...
  83. pmc Use of fibrin glue as a sealant at the anastomotic line in laparoscopic pyeloplasty: A randomised controlled trial
    Ahmed Farouk
    Department of Urology, Ain Shams University Hospital, Cairo, Egypt
    Arab J Urol 14:292-298. 2016
    To assess the effectiveness of fibrin glue as a sealant at the anastomotic line of a stentless laparoscopic pyeloplasty (LPP) repair instead of JJ stent insertion.
  84. pmc Gene expression profiling of hematologic malignant cell lines resistant to oncolytic virus treatment
    Nam Hee Lee
    SillaJen, Inc, Busan, Korea
    Oncotarget 8:1213-1225. 2017
    ..Up-regulation of PVRIG, LPP, CECR1, Arhgef6, IRX3, IGFBP2, CD1d were related to resistant to Pexa-Vec...
  85. pmc Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs
    H Xia
    Department of Physiology, University of California at San Francisco, San Francisco, California 94143, USA
    J Cell Biol 139:507-15. 1997
    ..Here, we identify actinin-associated LIM protein (ALP), a novel protein in skeletal muscle that contains an NH2-terminal PDZ domain and a COOH-terminal LIM ..
  86. ncbi Induction of endothelial monolayer permeability by phosphatidate
    D English
    Experimental Cell Research Laboratory, The Methodist Research Institute, Indianapolis, Indiana 46202
    J Cell Biochem 75:105-17. 1999
    ..an inhibitor of endothelial cell "ecto"-phosphatidate phosphohydrolase (PAP), a lipid phosphate phosphohydrolase (LPP) that efficiently hydrolyzes extracellular substrate...
  87. ncbi Attitudes to the right- and left: frontal ERP asymmetries associated with stimulus valence and processing goals
    William A Cunningham
    Department of Psychology, University of Toronto, Ontario, Canada
    Neuroimage 28:827-34. 2005
    ..Results revealed a late positive potential (LPP) beginning at about 475 ms post-stimulus and maximal over anterior sites...
  88. pmc High-resolution longitudinal MRI of the transition to heart failure
    Peter N Costandi
    Department of Bioengineering, University of California San Diego, La Jolla, California 92093 0613, USA
    Magn Reson Med 57:714-20. 2007
    ..Transgenic murine models of cardiac disease, such as the muscle LIM protein-deficient strain used in this study, offer populations of a reproducible phenotype that readily lend themselves ..
  89. ncbi A study of dendritic cell and MHC class II expression in dogs with immunomodulatory-responsive lymphocytic-plasmacytic pododermatitis
    Rory M Breathnach
    School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Dublin 4, Ireland
    Vet J 177:352-9. 2008
    The term immunomodulatory-responsive lymphocytic-plasmacytic pododermatitis (ImR-LPP) has previously been proposed to denote a sub-population of dogs with idiopathic pododermatitis...
  90. doi The persistence of attention to emotion: brain potentials during and after picture presentation
    Greg Hajcak
    Department of Psychology, Stony Brook University, Stony Brook, NY 11794 2500, USA
    Emotion 8:250-5. 2008
    ..The late positive potential (LPP) is a sustained P300-like component of the event-related potential that is enhanced after the presentation of ..
  91. doi The effect of weight loss on protein profiles of gastrocnemius muscle in rabbits: a study using 1D electrophoresis and peptide mass fingerprinting
    A M Almeida
    Instituto de Investigação Científica Tropical and Centro Interdisciplinar de Investigação em Sanidade Animal, Lisboa, Portugal
    J Anim Physiol Anim Nutr (Berl) 94:174-85. 2010
    ..Pyruvate kinase levels were 50% lower in the New Zealand Restricted group. LIM protein detection was absent in the control New Zealand group...
  92. doi Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I)
    Diogenes de Sousa Neto
    Molecular Biophysics Group, Chemistry Institute of São Carlos, University of Sao Paulo, Sao Carlos, SP, Brazil
    Chem Phys Lipids 164:184-95. 2011
    ..5 nm (short periodicity phase, SPP) and ∼12 nm (LPP) in the presence of the CER EOS-L and CER EOS-O...
  93. doi Humiliation as an intense emotional experience: evidence from the electro-encephalogram
    Marte Otten
    a Department of Social Psychology, University of Amsterdam, Amsterdam, The Netherlands
    Soc Neurosci 9:23-35. 2014
    ..The late positive potential (LPP), a measure of the level of perceived (negative), affect was markedly increased in humiliation scenarios compared ..
  94. ncbi Isolated linear lichen planopilaris: extremely rare when limited to the scalp
    Ashley B Delacerda
    Department of Dermatology, Texas Tech University Health and Science, 3601 4th St, Stop 9400, Lubbock, TX 79430, USA
    Cutis 92:303-5. 2013
    Lichen planopilaris (LPP) is a primary cicatricial alopecia that rarely presents in a linear distribution. We present a case of linear LPP that was isolated to the frontal scalp with extension down the forehead...
  95. pmc Self-reported trait mindfulness and affective reactivity: a motivational approach using multiple psychophysiological measures
    Danielle Cosme
    Department of Psychology, Stockholm University, Stockholm, Sweden Department of Psychology, University of Oregon, Eugene, Oregon, United States of America
    PLoS ONE 10:e0119466. 2015
    ..and neutral pictures would show relatively decreased early posterior negativity (EPN) and late positive potential (LPP) amplitudes, decreased skin conductance responses, and decreased subjective ratings for valence and arousal...
  96. doi Event-related potential signatures of perceived and imagined emotional and food real-life photos
    Fernando Marmolejo-Ramos
    Department of Psychology, Stockholm University, Stockholm, Sweden
    Neurosci Bull 31:317-30. 2015
    ..In this study, two ERP correlates, the early posterior negativity (EPN) and the late positive potential (LPP) for perceived and imagined emotional and food photographs were investigated...
  97. pmc Steep, coincident, and concordant clines in mitochondrial and nuclear-encoded genes in a hybrid zone between subspecies of Atlantic killifish, Fundulus heteroclitus
    Jessica L McKenzie
    Department of ZoologyUniversity of British ColumbiaVancouverBritish ColumbiaCanada Centre for Aquaculture and Environmental ResearchFisheries and Oceans CanadaWest VancouverBritish ColumbiaCanada
    Ecol Evol 6:5771-87. 2016
    ..genes (SLC25A3 and HDDC2), as well as SNPs in the myoglobin, 40S ribosomal protein S17, and actin-binding LIM protein genes, had clines that were coincident and concordant with the mitochondrial clines...
  98. pmc A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity
    Xiaojie Xu
    Department of Medical Molecular Biology, Beijing Institute of Biotechnology, Collaborative Innovation Center for Cancer Medicine, Beijing 100850, China
    Nat Commun 8:14059. 2017
    ..Our results provide novel insight into molecular mechanisms underlying CDC25 activity regulation. LIM protein inhibition or use of eLIM may be new strategies for improving tumour radiosensitivity.
  99. pmc The acylated precursor form of the colicin A lysis protein is a natural substrate of the DegP protease
    D Cavard
    Centre de Biochimie Biologie Moléculaire du Centre National de la Recherche Scientifique, Marseille, France
    J Bacteriol 171:6316-22. 1989
    ..The cleavage took place in lpp, pldA, and wild-type strans carrying plasmids which express the lysis protein following SOS induction and also in ..
  100. ncbi A new LIM protein containing an autoepitope homologous to "senescent cell antigen"
    A Rearden
    Department of Pathology, School of Medicine, University of California, San Diego, La Jolla 92093 0612
    Biochem Biophys Res Commun 201:1124-31. 1994
    ....
  101. ncbi The muscle regulatory and structural protein MLP is a cytoskeletal binding partner of betaI-spectrin
    M J Flick
    Department of Biological Sciences, Purdue University, West Lafayette, IN 47907 1392, USA
    J Cell Sci 113:1553-64. 2000
    Muscle LIM protein (MLP) is a striated muscle-specific factor that enhances myogenic differentiation and is critical to maintaining the structural integrity of the contractile apparatus...

Research Grants59

  1. Psychophysiology of Emotion in Parkinsons Disease
    JENNA B DIETZ; Fiscal Year: 2013
    ..Event-related potentials (LPP, P3), startle eye-blink, and motor reaction times will be used to index arousal/attention, vigilance, and modulated ..
  2. Temporal Dynamics and Neural Bases of Emotion Regulation Under Emotional Load
    James J Gross; Fiscal Year: 2013
    ..that (1a) AD will attenuate an electrocortical index of emotional stimulus processing (the late positive potential;LPP) at an early phase, but that CR will do so at a later phase, and importantly, (1b) the early attenuation of the LPP ..
  3. Suppression of Negative Affect Indexed by the Late Positive Potential in Smokers
    JENNIFER ANNE MINNIX; Fiscal Year: 2010
    ..cognitive reappraisal strategies to enhance or reduce the emotional intensity of affective stimuli, indexed by the LPP (Late Positive Potential) component of the ERP, and (b) to assess whether ERP measures of cognitive reappraisal ..
  4. Emotion Regulation, Executive Function, and Parkinson Disease
    Dawn Bowers; Fiscal Year: 2013
    ..2011) or an event related potential component of motivated attention, the late positive potential, LPP (Dietz et al., 2011a)...
  5. Susan S Smyth; Fiscal Year: 2014
    ..active LPA, which is in turn inactivated by enxymatic dephosphorylation by lipid phosphate phosphatases (LPP)...
  6. Characterization of new toxins (YmgD and YdfD) from E.coli, targeting cell wall
    Hisako Masuda; Fiscal Year: 2012
    ..Lol complex is responsible for translocating outer membrane lipoproteins, including Lpp, from inner the membrane to the outer membrane...
  7. Adonis K Hijaz; Fiscal Year: 2014
    ..patterns from injury in young fertile, old fertile and aged mice as measured by functional leak point pressure(LPP), morphometric outcomes and expression of paracrine factors in the micro environment of the continence mechanisms (..
  8. Ashok K Chopra; Fiscal Year: 2015
    ..Our studies indicated that mice immunized with the mutant strain of Y. pestis deleted for the lpp and pigmentation locus (pgm) genes were protected against developing pneumonic plague caused by the highly virulent ..
  9. Teresa A Milner; Fiscal Year: 2016
    ..alters: 1) the levels and/or subcellular distribution of enkephalins within MFs and in lateral perforant path (LPP) afferents to CA3 and 2) opioid-mediated LTP and/or other forms of opioid-mediated plasticity at MF/LPP- CA3 ..
  10. PPAR-gamma Signaling in Normal Pilosebaceous Units and in Scarring Alopecia
    Pratima Karnik; Fiscal Year: 2013
    ..Our studies with the lymphocytic CA, Lichen planopilaris (LPP), have yielded novel results which provide clues to disease pathogenesis...
  11. Discovery of Biomakers in Human Mitochondrial Disorders
    RONALD WAYNE DAVIS; Fiscal Year: 2011
    ..barcode tagging for multiplexed sequencing of exome libraries from multiple individuals as well as extending LPP-based capture to all 1,200 nuclear- encoded mitochondrial genes...
  12. The Role of Ceramide Kinase in Eicosanoid Synthesis
    Charles E Chalfant; Fiscal Year: 2012
    ..Our preliminary results also suggest that lipid phosphate phosphatase-3 (LPP-3), a member of the LPP family, is responsible for the catalytic degradation of C1P...
  13. Lei Zheng; Fiscal Year: 2015
    ..Based on our recent apo form crystal structure of the PgpB protein, an LPP homolog from E...
  14. Development of Efficient table-top laser-produced plasma sources for Water-Window
    SIVANANDAN S HARILAL; Fiscal Year: 2012
    ..table-top water-window radiation source for transmission X-ray microscope (TXM) based on laser- produced plasma (LPP) light source. LPP-based WW-TXM systems require a soft X-ray source that is efficient, stable and debris free...
  15. Noninvasive prenatal diagnosis using targeted DNA capture and sequencing.
    RONALD WAYNE DAVIS; Fiscal Year: 2012
    ..b>LPP-based capture combined with next- generation sequencing (e.g...
  16. Diego Loayza; Fiscal Year: 2014
    ..The central hypothesis of this proposal is that the LIM domain proteins TRIP6 and LPP, which have been implicated by our group in the repression of the DNA damage response at telomeres, specifically ..
  17. Suppression of Negative Affect Indexed by the Late Positive Potential in Smokers
    JENNIFER ANNE MINNIX; Fiscal Year: 2013
    ..This project will take the next step and will evaluate smokers who want to quit smoking, relating their LPP responses to the experimental tasks to treatment outcome...
  18. Andrew Hayhurst; Fiscal Year: 2014
    ..We had previously attempted to do this using the lpp-OmpA surface display platform and poorly soluble scFv antibodies but have since found out that the combination ..
  19. Jason D Robinson; Fiscal Year: 2016
    ..The late positive potential (LPP) ERP component will provide us with a central nervous system measure of motivational salience of the pictures...
  20. ACTININ ASSOCIATED LIM PROTEIN & FSH MUSCULAR DYSTROPHY
    David Bredt; Fiscal Year: 2002
    ..Recent molecular cloning studies have identified actinin-associated LIM protein (ALP), which is a novel component of the muscle cytoskeleton...
  21. Neural Markers of Emotional Reactivity in Youth Depression and Anxiety
    Autumn J Kujawa; Fiscal Year: 2013
    ..The late positive potential (LPP) in an event-related potential component sensitive to emotional stimuli10...
  22. MUSCLE CELLS MEDIATED GENE THERAPY FOR INCONTINENCE
    Michael Chancellor; Fiscal Year: 2005
    ..Measure urethral MDSC injection to improve sphincter function by assessing leak point pressure (LPP) and urethral strip contractility, 3...
  23. PREVENTION OF NEUROMOTOR DEFICITS WITH CHELATION THERAPY
    Amit Bhattacharya; Fiscal Year: 2000
    ..out with established techniques which have been used by us over 13 years on the Cincinnati Lead Program Project (LPP) cohort...
  24. Mechanisms of Vaginal Sling Effects on Continence
    Firouz Daneshgari; Fiscal Year: 2006
    ..Using a total of 125 animals, the effects of sling and vaginal dissection on cystometrogram, contractility, LPP, and morphometry of the urethral sphincter will be examined in five animal groups...
  25. Role of Cysteine-rich Protein 2 in Vascular Disease
    Shaw Fang Yet; Fiscal Year: 2005
    ..Cysteine-rich protein (CRP) 2, also known as smooth muscle LIM protein (SmLIM), is a member of the LIM-only CAP family...
  26. MOLECULAR PHARMACOLOGY OF LYSOPHOSPHATIDIC ACID
    Kevin Lynch; Fiscal Year: 2006
    ..as well as the goal of defining these compounds at recombinant LPA receptors and lipid phosphate phosphohydrolases (LPP). Our collaborators have shown that our lead LPA receptor antagonist is efficacious in several animal models...
  27. Inhaled Large Porous Particles for Treatment of MDR-TB
    David Edwards; Fiscal Year: 2006
    ..Specific research aims are to develop stable, LPP formulations of key anti-TB agents, establish their efficacy in animal models of TB, complete 28-day toxicology ..
  28. INTRACELLULAR ASSEMBLY OF PHOTORECEPTOR PROTEINS
    DOROTHY ROOF; Fiscal Year: 1999
    ..2) Identify additional members of the intracellular signaling pathway in the retina in which ab/LIM protein may be involved. 3) Characterize the modulation of ab/LIM function by phosphorylation...
  29. Functional Tissue Engineering for Stress Incontinence
    Michael Chancellor; Fiscal Year: 2006
    ..slings on micturition during continuous cystometry; b) Assess the effect of SIS or MDSC/SIS on leak point pressure (LPP) using the reliable and sensitive vertical tilt intravesical pressure clamp method; c) Evaluate the immunohistology ..
  30. Regulation of RLIM Activity by Phosphorylation
    Steven Johnsen; Fiscal Year: 2006
    unreadable] DESCRIPTION (provided by applicant): Current data indicates that the LIM protein network, including the LIM domain containing kinase (LIMK), the LIM-only (LMO) proteins, and LIM domain binding co-factors plays an important ..
  31. Regulation of phospholemman by phosphorylation
    JOSEPH MOORMAN; Fiscal Year: 2003
    ..in modulating protein-protein interactions between PLM and dimerization partners such as MLP, a muscle lim protein, and a novel kinase anchoring protein from oocyte that have been identified in yeast two-hybrid assays...
  32. SMLIM, A VASCULAR SMOOTH MUSCLE LIM PROTEIN
    Mukesh Jain; Fiscal Year: 2002
    ..Furthermore, identification of VAMC-specific cis- and trans-acting factors will be crucial to the future success of efforts to restrict the expression of foreign genes to the blood vessel wall for gene therapy of vascular disease. ..
  33. Cellular Functions of the Human Filamins
    Masumi Eto; Fiscal Year: 2007
    ..to FLNs A or C, and a new proline-rich-domain and LIM-domain protein that we have named FBLP-1 (Filamin-Binding LIM Protein-I), that binds to all three FLNs...
  34. TRANSCRIPTIONAL CIRCUITS CONTROLLING MYOGENESIS
    STEPHEN KONIECZNY; Fiscal Year: 2001
    ..Characterization of the novel bHLG factor (Mist1) and the muscle-specific LIM protein (MLP) as well as identifying the target genes of the MRFs during the establishment of the myogenic lineage is ..
  35. The Role of LIM Proteins in Cell Migration and Adhesion
    GREGORY LONGMORE; Fiscal Year: 2009
    ..cell function in all three systems using primary cells derived from mice deficient in family members of this LIM protein family and in vivo...
  36. CRC/PE FOR THE STUDY OF PSYCHOPATHOLOGY FOR THE ELDERLY
    Eric Caine; Fiscal Year: 1991
    ..Management/ Biostatistics, Research Clinical Assessment, Brain Acquisition, and Education/Training; and four research laboratories, including Psychopharmacology (LPP), Neuropsychology (LNP), Suicide Studies (LSS), and Neuroscience (LNS).
  37. SEXUAL DIMORPHISM IN SEIZURE CONTROL
    JANA VELISKOVA; Fiscal Year: 2002
    ..Rats of both sexes and various ages will be used. These studies may lead to the development of new antiepileptic treatments that take into the account sexual age-related differences. ..
  38. Electrophysiological Correlates of Anhedonia in Schizophrenia
    WILLIAM HORAN; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  39. Prenatal Corticosteroid Impact on Hippocampus
    LIBOR VELISEK; Fiscal Year: 2004
    ..The data of this proposal will be critical for determining long-term adverse effects of multiple course prenatal corticosteroid therapy and for the ameliorating these effects in the offspring. ..
  40. Thiol-Reactive Crosslinkers for Biomaterials
    Glenn Prestwich; Fiscal Year: 2004
    ..Fourth, these new materials will be evaluated for cytocompatibility and cell growth in vitro with murine fibroblasts. Finally, selected materials will be seeded with fibroblasts and injected into nude mice for in vivo tissue generation. ..
  41. GENE THERAPY FOR ARTHRITIS IN THE TNFA-TRANSGENIC MOUSE
    Edward Schwarz; Fiscal Year: 2002
    ..abstract_text> ..
  42. SQUALENE AND OXIDOSQUALENE CYCLASES
    Glenn Prestwich; Fiscal Year: 2002
    ....
  43. AROMATIC L-AMINO ACID DECARBOXYLASE MODULATION
    NORTON NEFF; Fiscal Year: 2003
    ..This proposal has direct clinical relevance for PD, as it addresses the functionality of an enzyme absolutely required for successful L-DOPA therapy. ..
  44. A role for mGluRs in synaptic plasticity and epilepsy
    Kristopher Bough; Fiscal Year: 2003
    ..Further, we anticipate that knowledge gained from this work may also prevent novel treatment strategies for controlling stroke- or trauma-induced brain damage. ..
  45. MECHANICAL REGULATION OF DILATED CARDIOMYOPATHY
    Jeffrey Omens; Fiscal Year: 2004
    ..We propose that these regional structural changes accompanies dilatory heart failure, and are mechanisms behind the reduction in fiber shortening and the ability of the wall to thicken during systole. ..
  46. Mouse Models for Interstitial Cystitis
    Edward Schwarz; Fiscal Year: 2004
    ..Finally, we will attempt to generate a transgenic mouse model of IC by targeting the expression of a secreted form of mouse protamine-1 (sMP1) to the transitional epithelium and evaluate these animals in our system. ..
  47. PACAP Overexpression and Voiding Function
    Edward Schwarz; Fiscal Year: 2004
    ..If successful, the mice will be distributed to interested labs to assist with the rigorous characterization of the models as they relate to the neurochemical organization of voiding function. ..
  48. Crosslinkable Hydrogels for Tympanic Membrane Repair
    Glenn Prestwich; Fiscal Year: 2004
    ..Third, we will evaluate the biocompability and otocompability of each gel in vivo by evaluating recovery of auditory function and middle ear histology. ..
  49. Endothelial Transmigration Across the RPE Barrier
    Mary Elizabeth Hartnett; Fiscal Year: 2005
    ..Increased knowledge of the mechanisms that cause this destructive phenomenon may lead to future means to prevent CNV in the neurosensory retina, and thus, reduce vision loss in AMD. ..
  50. Neural correlates of cognitive biases in social phobia
    Jason Moser; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  51. Multidisciplinary Study of Right Ventricular Dysplasia
    Jeffrey Towbin; Fiscal Year: 2005
    ..This integrated research grant proposal offers a substantial prospect of expanding the fund of clinical knowledge regarding ARVD and of localizing the gene(s) responsible for this disorder. ..
  52. Uropathogen Detection Using DNA Biosensors
    Bernard Churchill; Fiscal Year: 2006
    ..Specific Aim 4 will involve batch fabrication of the device and clinical examination of the association between urosensor results and clinical correlates of urinary tract infection...
  53. Phosphoinositide and Inositol Polyphosphate Probes
    Glenn Prestwich; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  54. Revitalizing Allografts for Craniofacial Reconstruction
    Edward Schwarz; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  55. Tumor perfusion in small animals with tomographic digital subtraction angiography
    Cristian Badea; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  56. TRANSMURAL DEFORMATION
    Jeffrey Omens; Fiscal Year: 2008
    ..We will test the hypothesis that minimizing the 'prestretch' tissue area can be used as an algorithm to select pacing sites which improve global and regional function in the failing heart. ..
  57. Effectiveness Trial of Attention Shaping for Schizophrenia
    Steven M Silverstein; Fiscal Year: 2010
    ....
  58. Computational Approach to Ligand Discovery for LPA GPCR and PPAR
    Abby L Parrill; Fiscal Year: 2010
    ..This research can therefore lead to new treatments for cardiovascular disease and cancer. ..
  59. PKC-EHN-PKD signal complex in cardiac remodeling
    Masahiko Hoshijima; Fiscal Year: 2009
    ..abstract_text> ..

Patents2

  1. Multiple-tumor aberrant growth genes
    Patent Number: EP0727487-A1; Date:1996-08-21
  2. MULTIPLE-TUMOR ABERRANT GROWTH GENES
    Patent Number: WO9625493-A1; Date:1996-08-22