Genomes and Genes
Gene Symbol: KCNK5
Description: potassium two pore domain channel subfamily K member 5
Alias: K2p5.1, KCNK5b, TASK-2, TASK2, potassium channel subfamily K member 5, K2P5.1 potassium channel, TWIK-related acid-sensitive K(+) channel 2, TWIK-related acid-sensitive K+ channel 2, acid-sensitive potassium channel protein TASK-2, potassium channel, subfamily K, member 1 (TASK-2), potassium channel, subfamily, member 5 (KCNK5), potassium channel, two pore domain subfamily K, member 5
Publications190 found, 100 shown here
- Upregulation of K2P5.1 potassium channels in multiple sclerosisStefan Bittner
Department of Neurology, University of Wurzburg, Wurzburg, Munster, Germany
Ann Neurol 68:58-69. 2010Activation of T cells critically depends on potassium channels. We here characterize the impact of K(2P)5.1 (KCNK5; TASK2), a member of the 2-pore domain family of potassium channels, on T-cell function and demonstrate its putative ..
- Amide local anesthetics potently inhibit the human tandem pore domain background K+ channel TASK-2 (KCNK5)Christoph H Kindler
Attending Physician, Department of Anesthesia, University Clinics, Kantonsspital, CH 4031 Basel, Switzerland
J Pharmacol Exp Ther 306:84-92. 2003..of local anesthetics on members of this ion channel family, we heterologously expressed the 2P K+ channels TASK-2 (KCNK5), TASK-1 (KCNK3), and chimeric TASK-1/TASK-2 channels in oocytes of Xenopus laevis...
- Tandem-pore domain potassium channels are functionally expressed in retinal (Müller) glial cellsS N Skatchkov
CMBN, Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamon, Puerto Rico 00960 6032
Glia 53:266-76. 2006....
- The effects of huperzine A and IDRA 21 on visual recognition memory in young macaquesLudise Malkova
Department of Pharmacology and the Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, 3900 Reservoir Rd NW, Washington, DC 20007, USA
Neuropharmacology 60:1262-8. 2011..b>Task 2 included, in each of 24 trials, a list of six objects presented in succession...
- Localization of the tandem pore domain K+ channel KCNK5 (TASK-2) in the rat central nervous systemAnja Gabriel
Department of Anesthesia and Operative Intensive Care Medicine, University of Koln, 50924, Koln, Germany
Brain Res Mol Brain Res 98:153-63. 2002..The 2P K+ channel TASK-2 (also named KCNK5) is sensitive to changes in extracellular pH, inhibited by local anesthetics and activated by volatile anesthetics...
- TASK-2 is expressed in proximal neurons in the rat retinaXiao Min Zhang
Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China
Neuroreport 20:946-50. 2009..In AII glycinergic amacrine cells, however, only faint punctuate staining, if any, was seen. In addition, ganglion cells were also intensely labeled by TASK-2...
- Mutation of KCNK5 or Kir3.2 potassium channels in mice does not change minimum alveolar anesthetic concentrationKarin M Gerstin
Department of Anesthesia and Perioperative Care, University of California, San Francisco 94110, USA
Anesth Analg 96:1345-9, table of contents. 2003..MAC) needed to prevent movement in response to a noxious stimulus in 50% of adult mice lacking functional KCNK5 potassium channel subunits and compared these results with those for heterozygous and wild-type mice...
- Decision making in pathological gambling: a comparison between pathological gamblers, alcohol dependents, persons with Tourette syndrome, and normal controlsAnna E Goudriaan
Amsterdam Institute for Addiction Research, Academic Medical Centre, University of Amsterdam, The Netherlands
Brain Res Cogn Brain Res 23:137-51. 2005..Deficits in decision making and feedback processing in PG should be addressed in treatment and incorporated more explicitly in theoretical models of PG...
- fMRI of parents of children with Asperger Syndrome: a pilot studySimon Baron-Cohen
Department of Psychiatry, Autism Research Centre, University of Cambridge, Douglas House, 18b Trumpington Road, Cambridge CB2 2AH, UK
Brain Cogn 61:122-30. 2006..People with autism or Asperger Syndrome (AS) show altered patterns of brain activity during visual search and emotion recognition tasks. Autism and AS are genetic conditions and parents may show the 'broader autism phenotype.'..
- Protective effects of Nicotiflorin on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model ratsJin ling Huang
Department of Pharmacology, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
Pharmacol Biochem Behav 86:741-8. 2007..These results suggest that Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats...
- Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and peripheryA D Medhurst
Neuroscience Research, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park, Essex CM19 5AW, Harlow, UK
Brain Res Mol Brain Res 86:101-14. 2001..Furthermore, identification of common areas of expression may help identify which channels, if any, associate to form heteromeric K+ channel complexes...
- Activation of the TASK-2 channel after cell swelling is dependent on tyrosine phosphorylationSigne Skyum Kirkegaard
Section of Cell and Developmental Biology, Dept of Biology, The August Krogh Bldg, Univ of Copenhagen, 13, Universitetsparken, DK 2100, Copenhagen, Denmark
Am J Physiol Cell Physiol 299:C844-53. 2010..It is suggested that the cytokine receptor-coupled JAK/STAT pathway is upstream of the swelling-induced phosphorylation and activation of TASK-2 in EATC...
- Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channelsNicole Bobak
University of Muenster, Department of neurology Inflammatory disorders of the nervous system and neurooncology, Domagkstr, 13, 48149 Muenster, Germany
Biochim Biophys Acta 1808:2036-44. 2011..This study explores a putative role of the newly identified K(2P) channels (TASK1, TASK2, TASK3 and TRESK) along with the voltage-gated potassium channel K(V)1...
- The stage-specific effect of alcohol on human information processingTom A Schweizer
Department of Psychology, University of Waterloo, Waterloo, ON, Canada
Psychopharmacology (Berl) 178:52-7. 2005..quick succession, performance on the second task is increasingly degraded as the temporal gap between task 1 and task 2 decreases...
- Evaluation of BioCreAtIvE assessment of task 2Christian Blaschke
Bioalma SL, Ronda de Poniente 4 2nd floor, Tres Cantos, E 28760, Madrid, Spain
BMC Bioinformatics 6:S16. 2005..In order to make text mining tools useable in real world scenarios, for instance to assist database curators during annotation of protein function, comparisons and evaluations of different approaches on full text articles are needed...
- Enhanced muscle fatigue occurs in male but not female ASIC3-/- miceLynn A Burnes
Graduate Program in Physical Therapy and Rehabilitation Science, Pain Research Program, Neuroscience Graduate Program, University of Iowa, Iowa City, IA 52242, USA
Am J Physiol Regul Integr Comp Physiol 294:R1347-55. 2008..two exercise protocols to measure exercise-induced muscle fatigue: (fatigue task 1, three 1-h runs; fatigue task 2, three 30-min runs)...
- When underadditivity of factor effects in the Psychological Refractory Period paradigm implies a bottleneck: evidence from psycholinguisticsDerek Besner
University of Waterloo, Waterloo, Ontario, Canada
Q J Exp Psychol (Hove) 62:2222-34. 2009..If the effect of a factor manipulated in Task 2 decreases as the stimulus onset asynchrony (SOA) between tasks decreases (underadditivity), the normative ..
- Deficits in facial emotion perception in adults with recent traumatic brain injuryRobin E A Green
Toronto Rehabilitation Institute, 550 University Avenue Room 1004, Toronto, Ont, Canada M5G 2A2
Neuropsychologia 42:133-41. 2004..Journal of Neuroscience 20(7) (2000) 2683] that damage to white matter tracts should give rise to emotion perception deficits...
- Fast, but error-prone, responses during acute alcohol intoxication: effects of stimulus-response mapping complexityTom A Schweizer
Department of Psychology, University of Waterloo, Waterloo, Ontario, Canada
Alcohol Clin Exp Res 28:643-9. 2004..This study used a psychological refractory period paradigm to investigate the effect of alcohol on the central, cognitive stage of information processing when task complexity is manipulated by altering stimulus-response compatibility...
- Synergists activation pattern of the quadriceps muscle differs when performing sustained isometric contractions with different EMG biofeedbackNicolas Place
INSERM ERM 207 Motricité Plasticité, Faculte des Sciences du Sport, Universite de Bourgogne, Dijon Cedex, France
Exp Brain Res 174:595-603. 2006....
- Biomechanical investigation of ambulatory training in patients with acetabular dysplasiaAkira Kanai
Department of Physical Therapy, Toyohashi SOZO University School of Rehabilitation, 20 1 Matsusita, Ushikawa cho, Toyohashi City, Aichi, Japan
Gait Posture 28:52-7. 2008..In exercise task 2, walking speed was changed in three stages from 60 steps/min (s-gait), 90 steps/min (n-gait), and 120 steps/min (f-..
- Evidence for automatic on-line adjustments of hand orientation during natural reaching movements to stationary targetsN Gosselin-Kessiby
Departement de Physiologie, Universite de Montreal, Montreal, Quebec, Canada
J Neurophysiol 99:1653-71. 2008..In letter-posting task 2, subjects first aligned their hand to the angle of the target and then reached to it with the instruction not to ..
- Evidence for a proprioception-based rapid on-line error correction mechanism for hand orientation during reaching movements in blind subjectsNadia Gosselin-Kessiby
Departement de Physiologie, Universite de Montreal, Montreal, Quebec, Canada H3C 3J7
J Neurosci 29:3485-96. 2009..In letter-posting task 2, blind subjects first aligned their hand to the orientation of the target and then subsequently reached to the ..
- Global synchronization in the theta band during mental imagery of navigation in humansYang Li
System Emotional Science, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani 2630, Toyama ken, Toyama 930 0194, Japan
Neurosci Res 65:44-52. 2009..Theta oscillation appears to play an important role in large-scale synchronization to form the functional neuronal networks required for mental navigation...
- Brazilian Portuguese version of the Iowa Gambling Task: transcultural adaptation and discriminant validityLeandro Fernandes Malloy-Diniz
Neuropsychology and Neurosciences Research Group, Universidade Fumec, Belo Horizonte, MG, Brazil
Rev Bras Psiquiatr 30:144-8. 2008..The aim of this work was to adapt the Iowa Gambling Task to Brazilian Portuguese, compare it with the original version and assess its validity...
- Neuroprotective effect of remacemide hydrochloride in a perforant pathway stimulation model of status epilepticus in the ratT Halonen
A I Virtanen Institute for Molecular Sciences, University of Kuopio, Finland
Epilepsy Res 34:251-69. 1999..did remacemide or carbamazepine treatment alleviate spatial memory impairment determined in a Morris water-maze task 2 weeks after PP stimulation...
- Genetic covariance among measures of information processing speed, working memory, and IQM Luciano
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia
Behav Genet 31:581-92. 2001..26 in females, 0.13 in males; genotypic: 0.34). A significant part of the genetic variance (43%) in IQ was not related to either choice RT or delayed response performance, and may represent higher order cognitive processes...
- Effects of 7 Hz-modulated 450 MHz electromagnetic radiation on human performance in visual memory tasksJ Lass
Biomedical Engineering Centre, Tallinn Technical University, Ehitajate tee 5, 19086 Tallinn, Estonia
Int J Radiat Biol 78:937-44. 2002..The aim was to examine low-level 7 Hz-modulated 450 MHz radiation effects on human performance in visually presented neuropsychological tasks associated with attention and short-term memory...
- Functional MRI of language in aphasia: a review of the literature and the methodological challengesBruce Crosson
Department of Veterans Affairs Rehabilitation Research and Development Brain Rehabilitation Research Center at the Malcom Randall VA Medical Center, Gainesville, Florida, USA
Neuropsychol Rev 17:157-77. 2007..While the promise of fMRI in the study of aphasia is great, there is much work to be done before this technique will be a useful clinical tool...
- The locus coeruleus involves in consolidation and memory retrieval, but not in acquisition of inhibitory avoidance learning taskBehrooz Khakpour-Taleghani
Cellular and Molecular Research Center and Department of Physiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Behav Brain Res 189:257-62. 2008..In conclusion, it seems that the nucleus locus coeruleus does not affect acquisition while it involves in the memory consolidation and retrieval of inhibitory avoidance learning task...
- Asymmetric activation of motor cortex controlling human anterior digastric muscles during speech and target-directed jaw movementsPaul F Sowman
Research Centre for Human Movement Control, Discipline of Physiology, School of Molecular and Biomedical Sciences, The University of Adelaide, Adelaide 5005, South Australia, Australia
J Neurophysiol 102:159-66. 2009..speaking a single word; 3) visually guided, nonspeech jaw movement that matched the jaw kinematics recorded during task 2; and 4) reciting a sentence...
- Effect of fixation tasks on multifocal visual evoked potentialsAlessandra Martins
Save Sight Institute, Department of Ophthalmology and Eye Health, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia
Clin Exp Ophthalmol 33:499-504. 2005..Three different foveal fixation conditions were utilized involving varying levels of task complexity. A more complex visual fixation task has been known to suppress peripheral signals in subjective testing...
- Predictors of driving exposure and avoidance in a field study of older drivers from the state of MarylandDavid E Vance
Department of Psychology, Center for Translational Research on Aging and Mobility, University of Alabama at Birmingham, 35294 2100, USA
Accid Anal Prev 38:823-31. 2006..A performance-based assessment, which included the Gross Impairment Screening battery and task 2 of the UFOV test, was completed by participants...
- Assessment of cognitive function in the heterozygous reeler mouseDilja D Krueger
Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, Ribicoff Research Facilities, CMHC, 34 Park Street, New Haven, CT 06508, USA
Psychopharmacology (Berl) 189:95-104. 2006..However, the effect of reelin haploinsufficiency on one of the cardinal symptoms of schizophrenia, the impairment of prefrontal-cortex-dependent cognitive function, has yet to be determined...
- Effects of an acute alpha-lactalbumin manipulation on mood and food hedonics in high- and low-trait anxiety individualsEllen Verschoor
Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
Br J Nutr 104:595-602. 2010..On both the test days, participants completed a stress-inducing task 2 h after the lunch. Mood and appetite were assessed using visual analogue scales...
- Selective block of the human 2-P domain potassium channel, TASK-3, and the native leak potassium current, IKSO, by zincCatherine E Clarke
Department of Biological Sciences, Imperial College London, Exhibition Road, London SW7 2AZ, UK
J Physiol 560:51-62. 2004..Therefore it is possible that inhibition of IK(SO) in cerebellar granule cells by synaptically released zinc may have important physiological consequences...
- The psychological refractory period: evidence for age differences in attentional time-sharingP A Allen
Department of Psychology, Cleveland State University, Ohio 44115, USA
Psychol Aging 13:218-29. 1998..psychological refractory period (PRP) experiments in which the stimulus onset asynchrony (SOA) between Task 1 and Task 2 was 150 ms, 250 ms, 600 ms, and 1,100 ms for both younger and older adults. H...
- Virtual reality flexible cystoscopy: a validation studyJ Shah
Academic Surgical Unit, Imperial College of Science, Technology and Medicine, St Mary s Hospital, London, UK
BJU Int 90:828-32. 2002..To validate a flexible cystoscopy simulator by determining if it could differentiate between expert and novice cystoscopists...
- Rhythmic and discrete elements in multi-joint coordinationDagmar Sternad
Department of Kinesiology, The Pennsylvania State University, 266 Rec Hall, University Park, PA 16803, USA
Brain Res 989:152-71. 2003..It was this rhythmic activity that posed the direct constraints on the initiation of the discrete movement...
- An evaluation of GO annotation retrieval for BioCreAtIvE and GOAEvelyn B Camon
European Molecular Biology Laboratory, European Bionformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
BMC Bioinformatics 6:S17. 2005..BioCreAtIvE task 2 was an experiment to test if automatically derived classification using information retrieval and extraction could ..
- The psychological refractory period in Parkinson's diseaseS Hsieh
Department of Psychology, National Chung Cheng University, Taiwan, ROC
Percept Mot Skills 91:893-902. 2000..The stimulus onset asynchrony (SOA) between Task 1 and Task 2 was 50 msec., 150 msec., and 650 msec...
- Event-related potentials evoked by multi-feature conflict under different attentive conditionsYuping Wang
Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053 PR China
Exp Brain Res 148:451-7. 2003..In task 1, subjects attended to the color of the stimuli and ignored the other attributes. In task 2, they were asked to attend to both color and global shape of stimuli and disregard the local shape...
- Mining protein function from text using term-based support vector machinesSimon B Rice
Faculty of Life Sciences, University of Manchester, UK
BMC Bioinformatics 6:S22. 2005..We participated in Task 2, which addressed assigning Gene Ontology terms to human proteins and selecting relevant evidence from full-text ..
- pH sensing in the two-pore domain K+ channel, TASK2Michael J Morton
School of Biomedical Sciences, Medical and Dental Building, University of Leeds, Leeds LS2 9NQ, United Kingdom
Proc Natl Acad Sci U S A 102:16102-6. 2005b>TASK2 is a member of the two-pore domain K(+) channel family that plays a role in acid-base homeostasis; TASK2 knockout animals have plasma electrolyte patterns typical of the human clinical condition of renal tubular acidosis...
- Effect of flat insoles with different Shore A values on posture stability in diabetic neuropathyJ A Van Geffen
Center for Rehabilitation, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Prosthet Orthot Int 31:228-35. 2007..It was found that prescribing insoles with a low Shore A value (15 degrees), compared to insoles with a higher Shore A value (30 degrees) has no significant negative effect on posture stability in patients with a diabetic neuropathy...
- Three-dimensional in vivo quantification of knee kinematics in cerebral palsyFrances T Sheehan
Physical Disabilities Branch, National Institutes of Health, National Institute of Child Health and Human Development and the Clinical Center, National Institutes of Health, Bethesda, MD 20892 1604, USA
Clin Orthop Relat Res 466:450-8. 2008..Fast phase contrast MRI may allow differentiation of patellofemoral and tibiofemoral function in various functional subtypes of cerebral palsy, providing insights into its management...
- Task completion time: Objective tool for assessment of technical skills in laparoscopic simulator for urology traineesShashi K Mishra
Department of Urology and Nephrology, Muljibhai Patel Society for Research in Nephrourology, Muljibhai Patel Urological Hospital, Nadiad 387 001, Gujarat, India
Indian J Urol 24:35-8. 2008..Laparoscopic surgical simulation is a valuable training tool for urology trainees...
- [Analysis of interference effects in simultaneous processing of 2 problems]T Schubert
Institut fur Psychologie, Humboldt Universitat Berlin
Z Exp Psychol 43:625-56. 1996..A well known result is that reaction time on task 2 (Rt2) increases with decreasing overlap of the two tasks...
- Incidental memory of differently processed odorsL Hvastja
Dipartimento di Psicologia Università di Trieste
Percept Mot Skills 85:235-44. 1997..test had to evaluate the intensity of each odor (Task 1), to judge the similarity of each odor to mint (Task 2), or to score each odor for pleasantness and sourness (Task 3)...
- High resolution spatiotemporal analysis of the contingent negative variation in simple or complex motor tasks and a non-motor taskR Q Cui
Department of Clinical Neurology, University of Vienna, Wahringer Gurtel 18 20, A 1090, Vienna, Austria
Clin Neurophysiol 111:1847-59. 2000....
- Early-onset schizophrenia is associated with impaired adolescent development of attentional capacity using the identical pairs continuous performance testEmily Thaden
The Zucker Hillside Hospital, Department of Psychiatry Research 75 59 263rd Street, Glen Oaks, NY 11004, USA
Schizophr Res 81:157-66. 2006....
- Parallel central processing between tasks: evidence from lateralized readiness potentialsMei Ching Lien
Department of Psychology, Oregon State University, Corvallis, Oregon 97331 5303, USA
Psychon Bull Rev 14:133-41. 2007..readiness potentials (LRPs) and behavioral measures to determine whether response activation for Task 1 and Task 2 can occur in parallel...
- Up-regulated astroglial TWIK-related acid-sensitive K+ channel-1 (TASK-1) in the hippocampus of seizure-sensitive gerbils: a target of anti-epileptic drugsDuk Soo Kim
Department of Anatomy, College of Medicine, Hallym University, Chunchon 200 702, South Korea
Brain Res 1185:346-58. 2007....
- Myocontrol in agingEric J Fimbel
Fatronik Foundation Research Center, Laboratoire Cognition et Facteurs humains EA 497, Institut de Cognitique, Bordeaux, France
PLoS ONE 2:e1219. 2007..However, when individual performance was examined, some aged individuals were found to perform as well as the young participants, congruently with the literature on good aging...
- The nature of phoneme representation in spoken word recognitionM Gareth Gaskell
Department of Psychology, University of York, York, UK
J Exp Psychol Gen 137:282-302. 2008..paradigm in which participants made forced-choice color categorization (Task 1) and phoneme categorization (Task 2) decisions at varying stimulus onset asynchronies...
- Frontal brain activation in young children during picture book reading with their mothersS Ohgi
Graduate School of Rehabilitation and Health Sciences, Seirei Christopher University, Hamamatsu, Shizuoka, Japan
Acta Paediatr 99:225-9. 2010..This study was to measure changes in frontal brain activation in young children during picture book reading with their mothers...
- Motor preparation is modulated by the resolution of the response timing informationAnthony N Carlsen
Department of Physical Therapy and Human Movement Sciences, Feinberg School of Medicine, Northwestern University, 645 N Michigan Ave, Chicago, IL 60611, USA
Brain Res 1322:38-49. 2010....
- The effects of everyday concurrent tasks on overground minimum toe clearance and gait parametersBrian W Schulz
HSR and D RR and D Center of Excellence Maximizing Rehabilitation Outcomes, James A Haley VA Hospital, 8900 Grand Oak Circle, Tampa, FL 33637 1022, USA
Gait Posture 32:18-22. 2010..The relationships between MTC, gait parameters, and older age or fall risk should be explored further in at-risk subjects and circumstances to elucidate potential tripping mechanisms...
- Effect of unaccustomed eccentric exercise on proprioception of the knee in weight and non-weight bearing tasksCarolina Vila-Chã
Centre for Sensory Motor Interaction SMI, Department of Health Science and Technology, Aalborg University, Fredrik Bajers Vej 7, D 3, DK 9220, Aalborg, Denmark
J Electromyogr Kinesiol 21:141-7. 2011..In conclusion, eccentric exercise of the quadriceps impairs proprioception of the knee both immediately after and 24h post exercise, but only in non-weight bearing tasks...
- Changes in reward contingency modulate the trial-to-trial variability of hippocampal place cellsAndrew M Wikenheiser
Graduate Program in Neuroscience, University of Minnesota, Minneapolis, Minnesota, USA
J Neurophysiol 106:589-98. 2011..These results suggest that changes in task demands can affect the firing statistics of hippocampal neurons, leading to changes in the properties of decoded neural representations...
- Osmotic tolerance and intracellular ion concentrations of bovine sperm are affected by cryopreservationA K Blässe
Clinic for Cattle, University of Veterinary Medicine Hannover, Hannover, Germany
Theriogenology 78:1312-20. 2012..In conclusion, cryopreserved sperm exhibit reduced tolerance to hypotonic stress, a decreased intracellular pH, and increased intracellular potassium level...
- Effect of nitric oxide synthase inhibitor L-NAME on fear extinction in rats: a task-dependent effectHuaiqing Luo
Department of Physiology, Changsha Medical University, Changsha 410219, Hunan, PR China
Neurosci Lett 572:13-8. 2014..In task 2, rats received fear conditioning in context A, extinction training in context B and extinction test in context A (..
- HIF-1α-mediated upregulation of TASK-2 K⁺ channels augments Ca²⁺ signaling in mouse B cells under hypoxiaDong Hoon Shin
Department of Physiology, Seoul National University College of Medicine, Seoul 110 799, Republic of Korea Division of Natural Medical Sciences, College of Health Science, Chosun University, Gwangju 501 759, Republic of Korea
J Immunol 193:4924-33. 2014..This is functionally important in maintaining the negative membrane potential and providing electrical driving force to control Ca(2+) influx...
- Investigation of brain electrophysiological properties among heroin addicts: Quantitative EEG and event-related potentialsFarid Motlagh
Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia
J Neurosci Res . 2016..Task 1 provided auditory P300 and P600 in association with working memory. Task 2 provided auditory P300 as well as small and large deviant MMN event-related potential (ERPs)...
- Spatial and dynamical handwriting analysis in mild cognitive impairmentJacek Kawa
Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta st 40, Zabrze, Poland Electronic address
Comput Biol Med 82:21-28. 2017..g. median height of the text block in task 2 being 22.3mm, IQR 12.9 in MCI and 20.2mm, IQR 8.7 in control group)...
- Can practice eliminate the psychological refractory period effect?M Van Selst
Department of Psychology, San Jose State University, California 95192, USA
J Exp Psychol Hum Percept Perform 25:1268-83. 1999..Refractory Period (PRP) experiment, where Task 1 required a speeded vocal response to an auditory stimulus and Task 2 required a speeded manual response to a visual stimulus...
- High resolution DC-EEG mapping of the Bereitschaftspotential preceding simple or complex bimanual sequential finger movementR Q Cui
Department of Clinical Neurology, University of Vienna and Ludwig Boltzmann Institute of Functional Brain Topography, Austria
Exp Brain Res 134:49-57. 2000..the Bereitschaftspotential (BP) preceding voluntary bimanual sequential simple (task 1) and complex movements (task 2) in supplementary/cingulate and primary motor areas (SCMA, MIs) using 64-channel direct current ..
- Selective influence of second target exposure duration and task-1 load effects in the attentional blink phenomenonP Jolicoeur
Department of Psychology, University of Waterloo, ON, Canada
Psychon Bull Rev 7:472-9. 2000..b>Task2 was always to report as many letters as possible from T2...
- Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transportRichard Warth
Institute of Physiology, Universitatsstrasse 31, 93053 Regensburg, Germany
Proc Natl Acad Sci U S A 101:8215-20. 2004The acid- and volume-sensitive TASK2 K+ channel is strongly expressed in renal proximal tubules and papillary collecting ducts...
- Resolving dual-task interference: an fMRI studyYuhong Jiang
Department of Psychology, Harvard University, Cambridge, MA 02138, USA
Neuroimage 22:748-54. 2004..two tasks are presented within a short stimulus-onset-asynchrony (SOA), reaction time of each task, especially task 2, is dramatically delayed...
- Prediction of development of fatigue during a simulated ambulance work task from physical performance testsM Barnekow-Bergkvist
Centre for Musculoskeletal Research, University of Gavle, Sweden
Ergonomics 47:1238-50. 2004..The high physical strain during carrying the loaded stretcher implies the importance of investigating whether improved performance, matching the occupational demands, could decrease the development of fatigue during strenuous tasks...
- Pancreatic two P domain K+ channels TALK-1 and TALK-2 are activated by nitric oxide and reactive oxygen speciesF Duprat
Institut de Pharmacologie Moleculaire et Cellulaire, CNRS UMR 6097, 660 route des Lucioles, Sophia Antipolis, 06560 Vabonne, France
J Physiol 562:235-44. 2005....
- Symbolic distance affects two processing loci in the number comparison taskChris Oriet
Department of Psychology, University of Regina, 3737 Wascana Parkway, Regina, Saskatchewan, S4S 0A2, Canada
Mem Cognit 33:913-26. 2005..The results show that (1) numeric information in Task 2 can be retrieved in parallel with capacity-demanding processing in Task 1 but (2) comparing two quantities ..
- Characterization of potassium channels involved in volume regulation of human spermatozoaJ P Barfield
Institute of Reproductive Medicine, University of Munster, Munster, Germany
Mol Hum Reprod 11:891-7. 2005..4, Kv1.5 and Kv1.7, acid-sensitive channel TASK2 and the beta-subunit minK (IsK) in regulatory volume decrease (RVD)...
- Backward response-level crosstalk in the psychological refractory period paradigmJeff Miller
Department of Psychology, University of Otago, Dunedin, New Zealand
J Exp Psychol Hum Percept Perform 32:149-65. 2006..models of psychological refractory period (PRP) tasks suggest that a Task 1 response should be unaffected by the Task 2 response in the same trial, because selection of the former finishes before selection of the latter begins...
- Contributions of prefrontal cue-, delay-, and response-period activity to the decision process of saccade direction in a free-choice ODR taskKei Watanabe
Department of Cognitive and Behavioral Sciences, Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan
Neural Netw 19:1203-22. 2006..The gradual increase of the directional selectivity in delay-period activity might correspond to neural correlates of the decision process of the saccade direction in the S-ODR task...
- Extracellular pH alkalinization by Cl-/HCO3- exchanger is crucial for TASK2 activation by hypotonic shock in proximal cell lines from mouse kidneyS L'Hoste
UMR Centre National de la Recherche Scientifique 6548, Universite de Nice Sophia Antipolis, 06108 Nice Cedex 2, France
Am J Physiol Renal Physiol 292:F628-38. 2007We have previously shown that K(+)-selective TASK2 channels and swelling-activated Cl(-) currents are involved in a regulatory volume decrease (RVD; Barriere H, Belfodil R, Rubera I, Tauc M, Lesage F, Poujeol C, Guy N, Barhanin J, ..
- The locus of temporal preparation effects: evidence from the psychological refractory period paradigmKarin M Bausenhart
Psychologisches Institut, Universitat Tubingen, Friedrichstr 21, 72072 Tubingen, Germany
Psychon Bull Rev 13:536-42. 2006..Consistent with the prediction of an early locus of temporal preparation, this effect propagated completely to the RT of Task 2 at short SOAs, but propagation diminished virtually to zero at long SOAs.
- Reading aloud is not automatic: processing capacity is required to generate a phonological code from printMichael Reynolds
Department of Psychology, University of Waterloo, Waterloo, Ontario, Canada
J Exp Psychol Hum Percept Perform 32:1303-23. 2006..Task 1 was a tone discrimination task and Task 2 was reading aloud...
- Role of TASK2 in the control of apoptotic volume decrease in proximal kidney cellsSebastien l'Hoste
UMR CNRS 6548, Universite de Nice Sophia Antipolis, 06108 Nice Cedex 2, France
J Biol Chem 282:36692-703. 2007..In a previous study, we demonstrated in kidney proximal cells that the TASK2 channel was involved in the K+ efflux that occurred during regulatory volume decrease...
- Effects of selective inhibition of N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) on mice in learning and memory tasksKrzysztof Lukawski
Department of Pathophysiology, Medical University of Lublin, Jaczewskiego 8, 20 090 Lublin, Poland
Eur J Pharmacol 579:202-7. 2008..In the Y-maze task, MK-801 (0.1 mg/kg i.p.) impaired alternation behavior and considerably increased locomotion in the Y-maze and locomotor activity test. These results indicate that NAALADase inhibition may impair alternation behavior...
- Viewer perspective affects central bottleneck requirements in spatial translation tasksElizabeth A Franz
Department of Psychology, Otago University, Dunedin, New Zealand
J Exp Psychol Hum Percept Perform 34:398-412. 2008..Dual tasks consisted of tone discriminations (Task 1) and spatial translations (Task 2) using PRP methods with different manipulations on perceptual and response demands...
- Relationships between driving simulator performance and driving test resultsJ C F de Winter
BioMechanical Engineering Department, Mechanical, Maritime and Materials Engineering, Delft University of Technology, The Netherlands
Ergonomics 52:137-53. 2009..45). It is recommended that researchers conduct more large-scale studies into the reliability and validity of simulator measures and on-road driving tests...
- Comparing ERP concomitant with stimulus-induced and self-paced movements: intracerebral recordings at various cortical sitesJ Louvel
INSERM U894, Centre Paul Broca, 2ter rue d Alesia, 75014 Paris, France
Neurophysiol Clin 39:149-58. 2009..To compare the shape, amplitude, and topographical distribution over sensorimotor and centroparietal cortex of two sets of ERP concomitant with the same type of movement (MCP), either visually-triggered (VT-MCP) or self-paced (SP-MCP)...
- Scientific assessment of endoscopic surgical skillsHiroyuki Egi
Department of Endoscopic Surgery and Surgical Science, Graduate School of Hiroshima University, Hiroshima, Japan
Minim Invasive Ther Allied Technol 19:30-4. 2010..The aim of task 1 was to move the tip of the endoscopic instrument on the tops of poles from A to C, and task 2 was to move it from the right pole B to the left pole D...
- Multisession, dual-task psychological refractory period practice benefits older and younger adults equallyPhilip A Allen
Department of Psychology, University of Akron, Akron, OH 44325 4301, USA
Exp Aging Res 35:369-99. 2009..Task 1 involved tone discrimination and Task 2 involved simultaneous letter-matching...
- Objective and subjective measures of pure-tone stream segregation based on interaural time differencesChristian Füllgrabe
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
Hear Res 291:24-33. 2012..requiring listeners to indicate whether they heard one or two streams during presentation of a 30-s long sequence (task 2). The A and B tones had equal but opposite ITDs and had the same or different frequencies of 500 and/or 707 Hz...
- Specifying social cognitive processes with a social dual-task paradigmRoman Liepelt
Institute for Psychology, University of Muenster Muenster, Germany
Front Hum Neurosci 6:86. 2012..dual-task that was made of an automatic imitation task (Person 1: Task 1) and a two-choice number task (Person 2: Task 2)...
- A pilot study on the effects of cognitive remediation on hemodynamic responses in the prefrontal cortices of patients with schizophrenia: a multi-channel near-infrared spectroscopy studyShenghong Pu
Division of Neuropsychiatry, Department of Brain and Neuroscience, Tottori University Faculty of Medicine, Yonago, Tottori, Japan Electronic address
Schizophr Res 153:87-95. 2014....
- The relationship between sympathetic nervous activity and cerebral hemodynamics and oxygenation: a study using skin conductance measurement and functional near-infrared spectroscopyLisa Holper
Biomedical Optics Research Laboratory BORL, Division of Neonatology, University Hospital Zurich, Frauenklinikstrasse 10, 8091 Zurich, Switzerland Electronic address
Behav Brain Res 270:95-107. 2014..Our findings are relevant for several neuroscientific research areas seeking to evaluate the interplay between cortical and peripheral affective performance. ..
- Strategies to combat auditory overload during vehicular command and controlSharon M Abel
Individual Behaviour and Performance Section, Defence Research and Development Canada Toronto Research Centre, 1133 Sheppard Avenue West, Toronto, Ontario, Canada M3K 2C9
Mil Med 179:1036-42. 2014..Participants encoded only those beginning with a preassigned call sign (Baron or Charlie). For Task 2, they agreed or disagreed with simple equations presented either over loudspeakers, as text on the laptop monitor, ..
- Bimanual and unimanual convergent goal-directed movement timesErrol R Hoffmann
a Department of Systems Engineering and Engineering Management, City University of Hong Kong, Kowloon Tong
J Mot Behav 47:232-45. 2015..Movements made with low ID showed a small effect of 1- or 2-handed movements, with the effective amplitude of the movement being reduced by about 20% when 2 hands were used. ..
- The CNS under pathophysiologic attack--examining the role of K₂p channelsPetra Ehling
Department of Neurology, University of Munster, Munster, Germany
Pflugers Arch 467:959-72. 2015..TASK1 and TREK1 channels have a neuroprotective effect on stroke development, whereas TASK2 channels have a detrimental effect on neuronal survival under ischemic conditions...
- Dynamic sound localization in catsJanet L Ruhland
Department of Neuroscience and Neuroscience Training Program, University of Wisconsin, Madison, Wisconsin
J Neurophysiol 114:958-68. 2015..Cats appear to be able to process dynamic auditory cues and execute complex motor adjustments to accurately localize auditory targets during rapid eye-head gaze shifts. ..
- How visual search relates to visual diagnostic performance: a narrative systematic review of eye-tracking research in radiologyA van der Gijp
Radiology Department, University Medical Center Utrecht, E01 132, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
Adv Health Sci Educ Theory Pract . 2016..Experimental research is needed to find out which search strategies can improve image perception in learners...
- Concurrent deployment of visual attention and response selection bottleneck in a dual-task: Electrophysiological and behavioural evidenceChristina B Reimer
a Department of Psychology, Humboldt Universitat zu Berlin, Berlin, Germany
Q J Exp Psychol (Hove) . 2016..The dual-task consisted of an auditory two-choice discrimination Task 1 and a conjunction search Task 2, which were presented at variable temporal intervals (stimulus onset asynchrony, SOA)...
- Fetal Exposure to Low Levels of the Plasticizer DEHP Predisposes the Adult Male Adrenal Gland for Endocrine DisruptionS Lee
1 Research Institute of the McGill University Health Centre, Montreal, Quebec H4A 3J1, Canada
Endocrinology . 2016..that were subjected to both early and late exposure revealed deregulation of genes for the potassium channel Kcnk5 and the retinoid-X receptors (RXR) Rxrα and Rxrβ, indicating that these entities are linked to endocrine ..
- Characterization of exploratory activity and learning ability of healthy and "schizophrenia-like" rats in a square corridor system (AMBITUS)G Horvath
Department of Physiology, Faculty of Medicine, University of Szeged, H 6720 Szeged, Dom ter 10, Hungary Electronic address
Physiol Behav 169:155-164. 2017..were exposed to two types of tasks repeatedly in two series: all (16) or only the inside (8) boxes (Task 1 or Task 2, respectively) were baited...
- Effects of a no-go Task 2 on Task 1 performance in dual - tasking: From benefits to costsMarkus Janczyk
Department of Psychology, Eberhard Karls University of Tubingen, Schleichstraße 4, 72076, Tubingen, Germany
Atten Percept Psychophys . 2016When two tasks are combined in a dual-task experiment, characteristics of Task 2 can influence Task 1 performance, a phenomenon termed the backward crosstalk effect (BCE)...
- Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteriesM J Gardener
School of Biological Sciences, Stopford Building, University of Manchester, Manchester M13 9PT
Br J Pharmacol 142:192-202. 2004....
- Information continuity across the response selection bottleneck: early parallel Task 2 response activation contributes to overt Task 2 performanceSandra J Thomson
Department of Psychology, Neuroscience and Behaviour, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4K1, Canada
Atten Percept Psychophys 75:934-53. 2013Several studies of dual-task performance have demonstrated Task 2 to Task 1 response priming (backward compatibility effects), indicating some degree of parallel response computation for concurrent tasks and suggesting that the well-..
- Validation of a functional MRI-based reward processing task as a non-invasive tooMARY LOUISE PHILLIPS; Fiscal Year: 2010....
- Picture Naming Electrified: Brain Electrophysiological Correlates Nathan D Maxfield; Fiscal Year: 2012..Results of this research will have implications for the development of psycholinguistically-focused assessment and treatment tools for stuttering. ..
- Diagnostic Biomarkers for Radicular PainLewis S Hanna; Fiscal Year: 2012....
- Development Of An Eye Drop To Treat PresbyopiaWilliam H Garner; Fiscal Year: 2012..If permanent changes in cornea health are observed, lower dose formulations will be prepared and tested;Task 2. Determine the ocular pharmacokinetics of our co-drug, its metabolites, SAM-cycle intermediates and redox balance...
- Executive Function Therapy for Stimulant AddictionWarren K Bickel; Fiscal Year: 2012..b>Task 2 will collect data on executive function assessment instruments from controls to develop an operational definition ..
- Sensimmer Virtual Phaco Trainer for Cataract SurgeryP Pat Banerjee; Fiscal Year: 2011..b>Task 2. Develop a Phase II capsulorhexis simulator...
- Neural mechanisms mediating inferential reasoning abilities in ratsCYNTHIA FAST; Fiscal Year: 2013..The results of these experiments can aid in the development of interventions facilitating the use of these cognitive processes in both educational and clinical settings to remediate age-related cognitive decline. ..
- Sensitivity to smoking reinforcement in women: menstrual cycle effectsElizabeth Van Voorhees; Fiscal Year: 2012....
- A NEW MECHANISM FOR TREATING OBESITYSalih J Wakil; Fiscal Year: 2012..b>Task 2: Evaluate dose to reduce weight gain and lower triglycerides, LDL and blood glucose...
- A new class of biodegradable synthetic biomaterial for seroma preventionMichael Craven; Fiscal Year: 2012..b>Task 2 - Determine the range of efficacy in vivo using a model involving the harvesting of the rat latissimus dorsi ..
- NEUROPHYSIOLOGICAL & MODELING STUDIES OF LOCUS COERULEUSGary Aston Jones; Fiscal Year: 2000..responsivity to unexpected environmental stimuli. ..
- Barbara J Weiland; Fiscal Year: 2014..The proposed K01 award is well aligned with the missions of NIH and NIDA. The project will train a promising scientist and help clarify neurobiological pathways to substance abuse, a significant public health priority. ..
- High throughput screening of bacterial collections for surface proteins of commerRoy H Hammerstedt; Fiscal Year: 2010..When successfully implemented, an enhanced method for assessing both new clinical paradigms [such as use of biotherapeutics] as well as improving old analyses [suboptimal diagnostic immunoassays] will be attained. ..
- IMAGING AND MODELING THERAPEUTIC MECHANISMS OF ACTIONPeter Fox; Fiscal Year: 2003....
- Transcatheter Intra-arterial Perfusion MRI Monitoring of Liver Tumor EmbolizationANDREW CHRISTIAN LARSON; Fiscal Year: 2010..b>Task 2: To test the hypothesis that TRIP-MRI contrast dose can be optimized intra-procedurally to permit short wash-out ..
- Dong Hyun Kim; Fiscal Year: 2014..b>Task 2.1: To determine in vivo targeting efficiency of magnetic nanodisks using both in vivo quantitative MRI ..
- SUD &Decision-Making: A Pilot Imaging Study of Parents &ChildrenChristina W Hoven; Fiscal Year: 2012....
- Tal Raz; Fiscal Year: 2014..b>Task 2: Develop a sensor configuration that can scale to 100s of channels...
- Denis G Sukhodolsky; Fiscal Year: 2016....
- Radiologists' performance in digital mammography and breast tomosynthesisAndrew D A Maidment; Fiscal Year: 2010..b>Task 2: We will design a graphical user interface for the radiologists to report their decisions after each time-..
- Self-regulatory Control and Eating: A Neuroimaging Study of Bulimia NervosaLaura A Berner; Fiscal Year: 2013....
- Task 2/F04: Pharmacokinetic and Safety/Tox Testing for TherapeuticsMARA KUMMINS; Fiscal Year: 2011..In addition, it can perform testing of therapeutics for safety and pharmacology, in small animals as well as non-human primates, under GLP where appropriate. ..
- Engineered Spores as Fluorogenic Biological Indicators for Sterility TestingBoris Rotman; Fiscal Year: 2009..For Task 1, BCR will collaborate with New Horizons Diagnostics Corp. (Columbia, MD). Task 2. To standardize and test the rBI for stability and reproducibility. Task 3...
- Engineered Spores as Fluorogenic Biological Indicators for Sterility TestingBoris Rotman; Fiscal Year: 2007..b>Task 2. Evaluate the biological indicator prototype by comparing it with conventional biological indicators using spore ..
- EVALULATION OF PRENATAL TESTS FOR CHROMOSOMAL DISORDERSA Washington; Fiscal Year: 1993..b>Task 2 will consist of detailed interviews with obstetrical patients undergoing genetic counseling at UCSF to assess ..
- SBIR TOPIC 294 PHASE 1 - DEVELOPMENT OF GLYCOSYLATION - SPECIFIC RESEARCHYie Hwa Chang; Fiscal Year: 2011..In the Phase I proposal, we propose to generate over 32 chicken polyclonal (Task 1) and 2-3 monoclonal IgY (Task 2) [unreadable] against specific Oglycosylation sites...
- Auditory Perception of Drug Names: Neighborhood EffectsBruce Lambert; Fiscal Year: 2006..abstract_text> ..
- EVALUATOR TRAINING MANIKIN FOR SPASTICITY AND STRENGTHDAVID ENGSBERG; Fiscal Year: 2003..b>Task 2: Test the SSKAT...
- Portable Brian Injury Biomarker Detection System with Integrated Microdialysis PrChampak Das; Fiscal Year: 2011..system with integrated microdialysis probe Task 1: Design and fabricate ePump driven integrated flow system Task 2: Detection of small molecule brain injury biomarkers Task 3: Detection of large molecule brain injury biomarker ..
- Fully Ambulatory Hot Flash Monitoring SystemROBERT LACKEY; Fiscal Year: 2005..b>Task 2 Ambulatory System Performance in Home Setting - This task will characterize the performance of the PhiloMetron ..
- Creating Research Files from CMS Data for Integration with Survey DataThomas MaCurdy; Fiscal Year: 2007..MDS and Medicaid); (3) conduct a pilot project demonstrating the effectiveness of the linkage approach created in Task 2; (4) work with CMS and our project survey partners?which include HRS, PSID and NLTCS?to establish protocols that ..
- Development of a Miniaturized EMG Telemetry SystemJohn Standeven; Fiscal Year: 2001..A miniature transmitter and receiver from Ramsey Electronics will form the nucleus of this unit. Task 2: Test the single channel EMG unit...
- BEHAVIOR & HORMONE MEDIATION OF HIPPOCAMPAL NEUROGENESISDiane Lee; Fiscal Year: 2001..abstract_text> ..
- BIOMEDICAL (BASIC)Abe Abuchowski; Fiscal Year: 2009..a schematic of the process), validation of a clean room at Prolong Pharmaceuticals to meet cGMP specifications (Task 2) and design and construction of the equipment required for the scale up production of PEG-Hb which will be ..
- Emotional Reactivity of Intimate Partner AbusersJULIA BABCOCK; Fiscal Year: 2003..abstract_text> ..
- Anti-curli immunotherapy for bacterial pneumoniaKanneganti Murthy; Fiscal Year: 2001..We expect to identify a murine anti-csgA MAb that provides potent protection against E. coli pneumonia induced lethality and pulmonary injury. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..
- MARKERS FOR STEM CELL-LIKE COLONIC CRYPT BASE CELLSBruce Boman; Fiscal Year: 2004..AIM 2: To determine gene expression patterns and levels for SCE marker genes in abnormal crypts, (FAP crypts). Task 2: compare gene expression levels and patterns in purified whole crypts from FAP vs...
- FUNCTIONAL PROPERTIES OF VTA NEURONSAnn Kosobud; Fiscal Year: 2000..The proposed experiments will provide a better understanding of the functional relationship among the various neuron subtypes in the VTA, and the contribution of these neurons to motivated behavior. ..
- Glycerol Kinase Deficiency as a Model to Understand Met*Katrina Dipple; Fiscal Year: 2005..transcriptome analysis in the whole animal model using the glycerol kinase knock-out (gyk k/o) mouse (Specific Aim/Task 2)...
- MANAGED CARE, FINANCIAL INCENTIVE & PHYSICIAN PRACTICECarol Simon; Fiscal Year: 2002..b>Task 2: Linked survey of physicians and practices: 2000 physicians and 2000 practice-level decision-makers in 5 states to ..
- Affective Dispositions and Attention to Emotion Info.RANDALL LARSEN; Fiscal Year: 2004....
- Radio Frequency Motion Tracking SystemDAVID ENGSBERG; Fiscal Year: 2003..Virtual movement of the transmitting antenna creates a Doppler shift in the signal at the receiver sensor. Task 2: Evaluation of the 2D device...
- Disinhibition and risk for early substance useCraig Colder; Fiscal Year: 2002..It will provide data that will inform etiological models of adolescent substance use, specifically with regard to an antisocial pathway. ..
- RECEPTOR PROFILING AND COMPOUND LIBRARY SCREENINGArthur Weissman; Fiscal Year: 2011..2. To perform binding affinity and/or functional activity assessments of active compounds (Task 2). 3...
- RECEPTOR PROFILING AND COMPOUND LIBRARY SCREENINGEMERICH EISENREICH; Fiscal Year: 2009..2. To perform binding affinity and/or functional activity assessments of active compounds (Task 2). 3...
- LOW-COST BIOSENSOR FOR REAL-TIME DIAGNOSIS OF BACTEREMIABoris Rotman; Fiscal Year: 2004..b>Task 2. Evaluating performance of the LEXSAS in terms of selectivity, analyte recovery and assay reproducibility. Task 3...
- Emotion Regulation in Suicidal Patients with BPDMARSHA LINEHAN; Fiscal Year: 2005..abstract_text> ..
- EXERCISE OF PATIENTS WITH HEMIPARETIC STROKERichard Macko; Fiscal Year: 2001....
- User adjustable support surfaces for wheelchair comfortDouglas Hobson; Fiscal Year: 2004..In sub-task 2 the cost feasibility will be determined...
- MACRORESTRICTION MAPPING APPLIED TO CHROMOSOME 5QCAROL WESTBROOK; Fiscal Year: 1990....
- CHROMATIC FACTORS IN LOW VISIONKenneth Knoblauch; Fiscal Year: 1990....
- NTP-CHEMICALS IN LABORATORY ANIMALSWARD RICHTER; Fiscal Year: 2000..Base Contract shall consist of Phase 1 (prestart activities) or Diisopropylcarbodiimide (Task 1), Methylene Blue (Task 2), Bromochloroacetic Acid (Task 3), Dibromoacetonitrile (Task 4), Dichloroacetic Acid (Task 5), and ..
- Double Jeopardy: Cognitive Decline in Depression & AgingVONETTA DOTSON; Fiscal Year: 2004..Accomplishing the aims outlined in this proposal will provide the foundation for future studies examining the effect of aging and depression on cognition and activities of daily living. ..
- A Compensatory Functional Neuroanatomy of ADHDJulie Schweitzer; Fiscal Year: 2007..A better understanding of strategies used in ADHD has potential educational implications for how children with ADHD learn and targets for treatment. ..
- DEVELOPMENTAL TOXICITY TESTINGCJ PRICE; Fiscal Year: 2000..three tasks: developmental toxicity range- finding studies (Task 1), FDA Segment 2 developmental toxicity testing (Task 2), and evaluation of newborn pups from reproductive toxicity test systems contract (N01-ES-15323) for developmental ..
- High resolution cone beam volume CT for breast imagingRuola Ning; Fiscal Year: 2003..abstract_text> ..
- ANALYSIS OF HIPPOCAMPAL ENCODING OF BEHAVIORAL DECISIONSRobert Hampson; Fiscal Year: 2004....
- Cognitive Control Deficits and Formal Thought DisorderJOHN KERNS; Fiscal Year: 2005..abstract_text> ..
- High resolution cone beam volume CT for breast imagingRuola Ning; Fiscal Year: 2006..abstract_text> ..
- ASSESSMENT OF IMPACT OF SUB ABUSE EDUC & PREV PROGRAMSLORAND SZALAY; Fiscal Year: 1990..be developed and tested for their potential to identify and measure changes in susceptibility to substance abuse (Task 2)...
- Gaq modulation of neuronal K+ channels: novel mechanisms and targetsDouglas A Bayliss; Fiscal Year: 2011..These experiments will characterize molecular substrates underlying native neuronal neurotransmitter-modulated background K+ currents and examine molecular mechanisms by which they are modulated. ..