hyccin

Summary

Gene Symbol: hyccin
Description: family with sequence similarity 126 member A
Alias: DRCTNNB1A, HCC, HLD5, HYCC1, hyccin, down regulated by Ctnnb1, a, down-regulated by CTNNB1 protein A
Species: human

Top Publications

  1. ncbi Multiple primary malignant tumors in patients with hepatocellular carcinoma. A review of 29 patients
    V de Pangher Manzini
    Divisione di Medicina Generale, Ospedale di Monfalcone, Italy
    Tumori 82:245-8. 1996
  2. pmc Possible role of Na(+)-K(+)-ATPase in the regulation of human corpus cavernosum smooth muscle contractility by nitric oxide
    S Gupta
    Department of Urology, Boston University School of Medicine, MA 02118, USA
    Br J Pharmacol 116:2201-6. 1995
  3. ncbi Sleep deprivation in the rat: XVIII. Regional brain levels of monoamines and their metabolites
    B M Bergmann
    Department of Psychiatry, University of Chicago, Illionis
    Sleep 17:583-9. 1994
  4. ncbi Management options for primary hepatocellular carcinoma. An overview
    J A Paraskevopoulos
    Department of Surgery, Athens Medical Center, Greece
    Acta Oncol 33:895-900. 1994
  5. ncbi Epidemiology of hepatocellular carcinoma in a province of northern Italy: prevalence of the risk factors and incidence in the population
    G C Mels
    Divisione di Medicina Interna, Ospedale Bolognini, Seriate, Bergamo, Italy
    Tumori 79:16-21. 1993
  6. ncbi Immunophenotypes and cytotoxic functions of lymphocytes in patients with hepatocellular carcinoma
    S S Chavan
    Cellular Immunology Unit, Tata Memorial Centre, Parel, Bombay, India
    Tumori 83:762-7. 1997
  7. ncbi sICAM-1, sCD95 and sCD95L levels in chronic liver diseases of different etiology
    C Tortorella
    Department of Internal Medicine, Immunology and Infectious Diseases, University of Bari Medical School, Policlinico, Italy
    Immunopharmacol Immunotoxicol 22:19-33. 2000
  8. ncbi [A seroepidemiological study of hepatitis viruses among the patients with different types of liver disease in Qinhuangdao]
    Q Ye
    Qinhuangdao hygiene and Antiepidemic Station 066000
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 11:37-40. 1997
  9. ncbi Possible contribution of serum activin A and IGF-1 in the development of hepatocellular carcinoma in Egyptian patients suffering from combined hepatitis C virus infection and hepatic schistosomiasis
    Mohamed Yousry Elsammak
    Department of Chemical Pathology, Medical Research Instituitre, Alexandria University, Alexandria, Egypt
    Clin Biochem 39:623-9. 2006
  10. ncbi [Melanoma antigen-3 expression in human hepatocellular carcinoma]
    S Cai
    Department of Surgery, People's Hospital, Beijing University, Beijing 100044, China
    Zhonghua Wai Ke Za Zhi 38:693-6. 2000

Research Grants

  1. Integrating plasma IGF-1 into novel classification of hepatocellular carcinoma
    Ahmed Kaseb; Fiscal Year: 2013
  2. Molecular Epidemiology of Chronic Liver Diseases
    Manal Hassan; Fiscal Year: 2009
  3. Dysregulation of the Tumor Microenvironment in Hepatocellular Carcinoma
    Lewis R Roberts; Fiscal Year: 2010
  4. Yujin Hoshida; Fiscal Year: 2016
  5. In-situ Gelling Protein Polymer Intravascular Embolic Agent for Hepatic Carcinoma
    Hamid Ghandehari; Fiscal Year: 2012
  6. SAMUEL WHEELER FRENCH; Fiscal Year: 2015
  7. Transgenic mouse models of HCV infection and replication
    Jieyun Jiang; Fiscal Year: 2012
  8. GUANGXIANG GEORGE LUO; Fiscal Year: 2016
  9. Pathogenesis and Treatment of Liver Disease in Transaldolase Deficiency
    Andras Perl; Fiscal Year: 2013
  10. Combination therapies for chronic HBV, liver disease and cancer
    Mark A Feitelson; Fiscal Year: 2012

Detail Information

Publications1787 found, 100 shown here

  1. ncbi Multiple primary malignant tumors in patients with hepatocellular carcinoma. A review of 29 patients
    V de Pangher Manzini
    Divisione di Medicina Generale, Ospedale di Monfalcone, Italy
    Tumori 82:245-8. 1996
    BACKGROUND: The study of patients with hepatocellular carcinoma (HCC) and multiple primary malignant tumors (MPMTs) is interesting from an etiopathogenetic as well as from a clinical point of view...
  2. pmc Possible role of Na(+)-K(+)-ATPase in the regulation of human corpus cavernosum smooth muscle contractility by nitric oxide
    S Gupta
    Department of Urology, Boston University School of Medicine, MA 02118, USA
    Br J Pharmacol 116:2201-6. 1995
    ..04 and 0.2 microM, respectively) of HCC strips contracted with 15 mM K+. Ouabain (0...
  3. ncbi Sleep deprivation in the rat: XVIII. Regional brain levels of monoamines and their metabolites
    B M Bergmann
    Department of Psychiatry, University of Chicago, Illionis
    Sleep 17:583-9. 1994
    ..disk-over-water method for 11-20 days and were guillotined along with yoked control (TSC) and home-cage control (HCC) rats...
  4. ncbi Management options for primary hepatocellular carcinoma. An overview
    J A Paraskevopoulos
    Department of Surgery, Athens Medical Center, Greece
    Acta Oncol 33:895-900. 1994
    Hepatocellular carcinoma (HCC) is the seventh most common cancer in men and the ninth most common cancer in women with 500,000 to 1,000,000 new cases per year...
  5. ncbi Epidemiology of hepatocellular carcinoma in a province of northern Italy: prevalence of the risk factors and incidence in the population
    G C Mels
    Divisione di Medicina Interna, Ospedale Bolognini, Seriate, Bergamo, Italy
    Tumori 79:16-21. 1993
    AIMS: Epidemiologic studies on hepatocellular carcinoma (HCC) in limited geographic areas of Italy are rare, and most of them derive from autopsies...
  6. ncbi Immunophenotypes and cytotoxic functions of lymphocytes in patients with hepatocellular carcinoma
    S S Chavan
    Cellular Immunology Unit, Tata Memorial Centre, Parel, Bombay, India
    Tumori 83:762-7. 1997
    AIMS AND BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers in Asia. Immunological mechanisms are thought to play an important role in the control of tumor progression...
  7. ncbi sICAM-1, sCD95 and sCD95L levels in chronic liver diseases of different etiology
    C Tortorella
    Department of Internal Medicine, Immunology and Infectious Diseases, University of Bari Medical School, Policlinico, Italy
    Immunopharmacol Immunotoxicol 22:19-33. 2000
    ..HCV)-induced chronic hepatitis (CH-C), HCV-positive liver cirrhosis with superimposed hepatocellular carcinoma (HCC), autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) and alcoholic liver cirrhosis (ALC)...
  8. ncbi [A seroepidemiological study of hepatitis viruses among the patients with different types of liver disease in Qinhuangdao]
    Q Ye
    Qinhuangdao hygiene and Antiepidemic Station 066000
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 11:37-40. 1997
    ..types of liver disease (acute hepatitis, AH; chronic hepatitis, CH; liver cirrhosis, LC; hepatocellular carcinoma, HCC) from hospitals in Qinhuangdao city during 1992-1995...
  9. ncbi Possible contribution of serum activin A and IGF-1 in the development of hepatocellular carcinoma in Egyptian patients suffering from combined hepatitis C virus infection and hepatic schistosomiasis
    Mohamed Yousry Elsammak
    Department of Chemical Pathology, Medical Research Instituitre, Alexandria University, Alexandria, Egypt
    Clin Biochem 39:623-9. 2006
    ....
  10. ncbi [Melanoma antigen-3 expression in human hepatocellular carcinoma]
    S Cai
    Department of Surgery, People's Hospital, Beijing University, Beijing 100044, China
    Zhonghua Wai Ke Za Zhi 38:693-6. 2000
    OBJECTIVE: To investigate the expression of melanoma antigen-3 (MAGE-3) mRNA in human hepatocellular carcinoma (HCC) and probe into the theoretical feasibility that MAGE-3 antigens can be developed as a new peptide vaccine for ..
  11. ncbi Long-term follow-up of a patient with hepatocellular carcinoma associated with triple hepatitis virus (HBV, HDV, HCV) infection
    T Koda
    Institute of Clinical Research, Kure National Hospital, Hiroshima, Japan
    Kansenshogaku Zasshi 72:1188-92. 1998
    A 69-year-old Japanese man with hepatocellular carcinoma (HCC) associated with triple hepatitis viruses [hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatitis D virus (HDV)] infection is reported...
  12. ncbi NKT and CD8 lymphocytes mediate suppression of hepatocellular carcinoma growth via tumor antigen-pulsed dendritic cells
    Oren Shibolet
    Liver Unit, Department of Medicine, Hadassah University Hospital, Jerusalem, Israel
    Int J Cancer 106:236-43. 2003
    ..Hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) expresses hepatitis B virus surface antigen (HBsAg) on its cell surface and may serve as a tumor-associated ..
  13. ncbi Immunolocalization of cellular fibronectins in the normal liver, cirrhosis, and hepatocellular carcinoma
    G K Koukoulis
    Department of Pathology, Rush Medical College, Chicago, IL 60612, USA
    Ultrastruct Pathol 19:37-43. 1995
    ..cryosections of normal adult livers (n = 5), cirrhotic livers (n = 20), and livers with hepatocellular carcinoma (HCC) (n = 10) by the avidin-biotin-complex method with specific Mabs to the extradomains A and B (EDA, EDB) and ..
  14. ncbi A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China
    G S Qian
    Shanghai Cancer Institute, People's Republic of China
    Cancer Epidemiol Biomarkers Prev 3:3-10. 1994
    ..After close to 70,000 person-years of follow-up, 55 incident cases of hepatocellular carcinoma (HCC) had been identified...
  15. ncbi Clinicopathologic factors influencing long-term survival after resection for hepatocellular carcinoma
    H P Tsai
    Department of General Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan
    Chang Gung Med J 23:529-35. 2000
    ..a survival longer than 5 years with no recurrence in patients after resection for hepatocellular carcinoma (HCC)...
  16. ncbi [Hepatitis B virus DNA detection by means of polymerase chain reaction in patients with chronic hepatitis and hepatocellular carcinoma]
    Y Song
    Department of Microbiology, Second Military Medical University, Shanghai 200433
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 11:220-2. 1997
    ..labeled probe were done in 61 patients with chronic hepatitis (CH) and 47 patients with hepatocellular carcinoma (HCC) to investigate the relationship between HBV replication and serum markers. The HBV DNA was detected in 90...
  17. ncbi Serum copper and ceruloplasmin in early and in advanced hepatocellular carcinoma: diagnostic and prognostic relevance
    M Casaril
    Istituto di Patologia Medica, Verona, Italy
    Tumori 75:498-502. 1989
    ..of serum copper (S-Cu) and ceruloplasmin and their pathophysiologic significance in human hepatocellular carcinoma (HCC), we studied 49 patients with HCC (20 of which were submitted to partial hepatectomy) compared with 110 patients ..
  18. ncbi Influence of hepatitis C virus infection on circulating levels of sICAM-1 and VEGF in patients with hepatitis C and hepatocellular carcinoma (HCC) and their role in enhancing detection of HCC
    Ghada F Helaly
    Department of Microbiology, Medical Research Institute, Alexandria University, Alexandria, Egypt
    Egypt J Immunol 13:27-38. 2006
    ..liver damage and a long viral persistence associated with an increased risk of developing hepatocellular carcinoma (HCC). Intercellular adhesion molecule-1 (ICAM-1) plays a key role during liver inflammation and also expressed in HCC...
  19. pmc Mechanical properties of hepatocellular carcinoma cells
    Gang Zhang
    Department of Pathophysiology, The Third Military Medical University, Chongqing 400038, China
    World J Gastroenterol 8:243-6. 2002
    To study the viscoelastic properties of human hepatocytes and hepatocellular carcinoma (HCC) cells under cytoskeletal perturbation, and to further to study the viscoelastic properties and the adhesive properties of mouse hepatoma cells (..
  20. ncbi Molecular targets for prevention of hepatocellular carcinoma
    Hubert E Blum
    Department of Medicine II, University Hospital Freiburg, Germany
    Dig Dis 20:81-90. 2002
    Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in some areas of the world with an extremely poor prognosis...
  21. pmc Helicobacter infection in hepatocellular carcinoma tissue
    Shi Ying Xuan
    Department of Microbiology, School of Medicine, Qingdao University, Qingdao 266021, Shandong Province, China
    World J Gastroenterol 12:2335-40. 2006
    To investigate whether Helicobacter species (Helicobacter spp.) could be detected in hepatocellular carcinoma (HCC) tissue.
  22. ncbi Lack of correlation between hepatitis B virus infection and the increasing incidence of primary liver cancer in Sweden
    J Kaczynski
    Department of Medicine, Ostra Hospital, , Sweden
    Acta Oncol 30:811-3. 1991
    ..of chronic hepatitis B virus (HBV) infection for liver cancer development 40 cases with hepatocellular carcinoma (HCC) were examined for the presence of HBV surface antigen and HBV core antigen in the cancer and in the surrounding ..
  23. ncbi Newly clarified target may shed light on the anti-viral treatment of hepatitis C
    Y Inagaki
    Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Biosci Trends 2:1. 2008
    ..frequently become chronic, and chronic hepatitis tends to progress to liver cirrhosis and hepatocellular carcinoma (HCC)...
  24. pmc Hepatocellular carcinoma with obstructive jaundice: diagnosis, treatment and prognosis
    Lun Xiu Qin
    Liver Cancer Institute, Fudan University, 136 Yi Xue Yuan Road, Shanghai 200032, China
    World J Gastroenterol 9:385-91. 2003
    Obstructive jaundice as the main clinical feature is uncommon in patients with hepatocellular carcinoma (HCC). Only 1-12 % of HCC patients manifest obstructive jaundice as the initial complaint...
  25. ncbi [Diagnostic value of multislice spiral CT and MRI in detection of tumor recurrence after liver transplantation for hepatocellular carcinoma]
    Jin Wang
    Department of Diagnostic Radiology, The Third Affiliated Hospital, Sun Yat Sen University, Guangzhou, China
    Zhonghua Zhong Liu Za Zhi 31:691-6. 2009
    To investigate the manifestation and diagnostic value of multislice spiral CT (MSCT) and MRI imaging in detection of tumor recurrence after liver transplantation for hepatocellular carcinoma (HCC).
  26. pmc Liver resection as a bridge to transplantation for hepatocellular carcinoma on cirrhosis: a reasonable strategy?
    Rene Adam
    Centre Hépato Biliare, Hospital Paul Brousse, Assistance Publique, Hospitaux de Paris Université Paris Sud Villejuif, France
    Ann Surg 238:508-18; discussion 518-9. 2003
    To assess the viability of a strategy of primary resection with secondary liver transplantation (LT) for hepatocellular carcinoma (HCC) on cirrhosis.
  27. ncbi Detection of serum HBV DNA and anti-HCV antibody in HBsAg seronegative patients with hepatocellular carcinoma in Japan
    S Tokeshi
    Second Department of Medicine, Kurume University School of Medicine, Japan
    Kansenshogaku Zasshi 70:103-7. 1996
    One hundred eight patients with hepatocellular carcinoma (HCC) underwent serologic testing for HBsAg, antibodies to HBs (anti-HBs), HBc (anti-HBc) and HCV (anti-HCV), and an assay for hepatitis B virus (HBV) DNA by the polymerase chain ..
  28. ncbi Hepatoma today: therapeutic experiences of multimodal approach
    Z Y Tang
    Liver Cancer Institute, Shanghai Medical University, People's Republic of China
    Tumori 79:166-9. 1993
    AIMS AND BACKGROUND: Hepatocellular carcinoma (HCC) ranks third of cancer deaths in China, it kills 100,000 patients every year. In Italy HCC is an increasing malignant tumor and kills about 7000 patients every year...
  29. ncbi A cohort study of serum testosterone and hepatocellular carcinoma in Shanghai, China
    J M Yuan
    Shanghai Cancer Institute, People's Republic of China
    Int J Cancer 63:491-3. 1995
    A nested case-control study of HCC based on a cohort of 18,244 middle-aged men in Shanghai, China, who had been followed for an average of 5.3 years, was conducted...
  30. ncbi Medical treatment of hepatocellular carcinoma: any progress?
    M Colleoni
    Department of Medical Oncology, Ospedale Civile, Castelfranco Veneto, Italy
    Tumori 80:315-26. 1994
    Hepatocellular carcinoma (HCC) remains one of the most common neoplasms worldwide. Curative treatment options include liver transplantation or resection...
  31. ncbi Targeted chemotherapy for unresectable primary and metastatic liver cancer
    T Konno
    First Department of Surgery, Kumamoto University School of Medicine, Japan
    Acta Oncol 33:133-7. 1994
    ..therapy with these oily anticancer agents was performed in 330 patients with unresectable hepatocellular carcinoma (HCC) and 110 patients with unresectable metastatic liver cancer...
  32. ncbi Surveillance of cirrhosis for hepatocellular carcinoma: systematic review and economic analysis
    J Thompson Coon
    Peninsula Technology Assessment Group PenTAG, Peninsula Medical School, Exeter, UK
    Health Technol Assess 11:1-206. 2007
    ..C virus (HCV)-related], using periodic serum alpha-fetoprotein (AFP) testing and/or liver ultrasound examination, to detect hepatocellular carcinoma (HCC), followed by treatment with liver transplantation or resection, where appropriate.
  33. ncbi Epidemiological characteristics and risk factors of hepatocellular carcinoma
    C J Chen
    Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei, Republic of China
    J Gastroenterol Hepatol 12:S294-308. 1997
    Hepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking variation in HCC incidence rates between various countries, with a highest-to-lowest ratio of 112.5 for males and 54.7 for females...
  34. pmc Long-term survival and pattern of recurrence after resection of small hepatocellular carcinoma in patients with preserved liver function: implications for a strategy of salvage transplantation
    Ronnie Tung Ping Poon
    Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Ann Surg 235:373-82. 2002
    ..results and pattern of recurrence after resection of potentially transplantable small hepatocellular carcinomas (HCC) in patients with preserved liver function, with special reference to the implications for a strategy of salvage ..
  35. pmc The point mutation of p53 gene exon7 in hepatocellular carcinoma from Anhui Province, a non HCC prevalent area in China
    Hu Liu
    Laboratory of Molecular Biology and Department of Biochemistry, Anhui Medical University, Hefei 230032, Anhui Province, China
    World J Gastroenterol 8:480-2. 2002
    In hepatocellular carcinoma (HCC) prevalent areas of China, the point mutation of p53 exon7 is highly correlated with Hepatitis B virus(HBV) infection and aflatoxin B intake...
  36. ncbi 240 hepatocellular carcinomas: ultrasound features, tumor size, cytologic and histologic patterns, serum alpha-fetoprotein and HBs Ag
    T Livraghi
    Servizio di Radiologia, Ospedale Civile, Vimercate, Italia
    Tumori 73:507-12. 1987
    Two hundred and forty cases of hepatocellular carcinomas (HCC), diagnosed by ultrasonography and fine needle biopsy, were studied. The following parameters were investigated: 1...
  37. pmc Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma
    Hwai I Yang
    Genomics Research Center, Academia Sinica and Graduate Institute of Epidemiology, National Taiwan University, Taipei, Taiwan
    J Natl Cancer Inst 100:1134-43. 2008
    The risk of hepatocellular carcinoma (HCC) increases with increasing level of hepatitis B virus (HBV) in serum (viral load)...
  38. pmc Prediction of recurrence and prognosis in patients with hepatocellular carcinoma after resection by use of CLIP score
    Wen He Zhao
    Department of Oncosurgery, The First Affiliated Hospital, Zhejiang University, Medical College, 79 Qingchun, Hangzhou 310003, Zhejiang Province, China
    World J Gastroenterol 8:237-42. 2002
    The survival time of patients with hepatocellular carcinoma (HCC) after resection is hard to predict. Both residual liver function and tumor extension factors should be considered...
  39. pmc Screening serum hepatocellular carcinoma-associated proteins by SELDI-based protein spectrum analysis
    Jie Feng Cui
    Liver Cancer Institute, Zhongshan Hospital, Fudan University, 136 Yi Xue Yuan Road, Shanghai 200032, China
    World J Gastroenterol 14:1257-62. 2008
    To find out potential serum hepatocellular carcinoma (HCC)-associated proteins with low molecular weight and low abundance by SELDI-based serum protein spectra analysis, that will have much application in the diagnosis or differentiated ..
  40. ncbi [Determination of expression of eight p53-related genes in hepatocellular carcinoma with tissue microarrays]
    Ming Hua Zhu
    Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai, 200433, PR China
    Ai Zheng 22:680-5. 2003
    ..that abnormal expression of p53 gene family is correlated with the development of hepatocellular carcinoma (HCC)...
  41. ncbi [Long term (5 years) outcome of radiofrequency ablation for hepatocellular carcinoma in 256 cases]
    Min Hua Chen
    Department of Ultrasound, Peking University School of Oncology, Beijing Cancer Hospital, Beijing 100036, China
    Beijing Da Xue Xue Bao 37:671-2. 2005
    ..Of the 256 HCC patients, 206 were male and 50 were female (mean age, 56.8 years; range, 24-80 years)...
  42. doi Hepatocellular carcinoma is associated with an increased risk of hepatitis B virus recurrence after liver transplantation
    Luciana C Faria
    INSERM, U 785, Villejuif, France
    Gastroenterology 134:1890-9; quiz 2155. 2008
    ..The role of hepatocellular carcinoma (HCC) in HBV recurrence remains unclear. We investigated the association between HCC pre-OLT and HBV recurrence post-OLT.
  43. doi [Selective deposition of agrin in the microvasculature of hepatocellular carcinoma: aspects in pathogenesis and differential diagnosis]
    Péter Tátrai
    Semmelweis Egyetem, Patológiai Tudományok Doktori Iskola 1091, Budapest
    Magy Onkol 52:379-83. 2008
    Hepatocellular carcinoma (HCC) accounts for 90% of primary liver cancers and is the fifth most common malignancy worldwide. HCC typically develops in the cirrhotic liver...
  44. ncbi Validation of the modified TNM-Izumi classification for hepatocellular carcinoma
    C Staudacher
    Department of Emergency Surgery, Surgical Oncology, University of Milan, School of Medicine, San Raffaele Scientific Institute, Italy
    Tumori 86:8-11. 2000
    ..53 cirrhotic patients (40 males, 13 females; mean age, 65 years; range, 43-81) who underwent hepatic resection for HCC. RESULTS: The 1-, 3-, and 5-year overall survivals were: 89%, 54%, and 50%, with disease-free survivals of 70%, 38%,..
  45. ncbi A decrease in AFP level related to administration of interferon in patients with chronic hepatitis C and a high level of AFP
    Shiro Murashima
    Department of Internal Medicine, Kurume Medical Center, Kurume, Fukuoka, Japan
    Dig Dis Sci 51:808-12. 2006
    It is known that there is a very high incidence of hepatocellular carcinoma (HCC) among patients with type C chronic hepatitis and cirrhosis, and alpha -fetoprotein (AFP) has been widely used as a diagnostic marker for HCC...
  46. ncbi Megestrol acetate in unresectable hepatocellular carcinoma
    M Colleoni
    Division of Medical Oncology, City Hospital, Castelfranco Veneto, Italy
    Tumori 81:351-3. 1995
    ..BACKGROUND: No consolidated medical treatment has yet been established for unresectable hepatocellular carcinoma (HCC). A possible interference of hormones in the pathogenesis and cellular growth of HCC has been suggested...
  47. ncbi Suppression of hepatocellular carcinoma growth via oral immune regulation towards tumor-associated antigens is associated with increased NKT and CD8+ lymphocytes
    Oren Shibolet
    Liver Unit, Department of Medicine, Hadassah University Hospital, Jerusalem, Israel
    Oncology 66:323-30. 2004
    ..Adoptive transfer of orally immunomodulated lymphocytes suppressed the growth of hepatocellular carcinoma (HCC) expressing HBsAg in athymic mice. NKT lymphocytes play a role in the defense against tumor growth.
  48. ncbi Metastases in cases with hepatocellular carcinoma in relation to clinicopathologic features of the tumor. An autopsy study from a low endemic area
    J Kaczynski
    Department of Medicine, , Ostra sjukhuset, Sweden
    Acta Oncol 34:43-8. 1995
    In order to study clinicopathologic features of hepatocellular carcinoma (HCC) and their relation to metastatic growth, all autopsied cases with confirmed HCC (n = 490) from a period with a high autopsy frequency in a well-defined ..
  49. pmc Hepatocellular carcinoma: an emerging problem with hepatitis C
    L Jeffers
    Department of Hepatology, Miami VA Medical Center University of Miami School of Medicine, FL 33136, USA
    J Natl Med Assoc 92:369-71. 2000
    Hepatocellular carcinoma (HCC) is emerging as a major problem in the United States, primarily due to the development of liver cancer in patients with cirrhosis secondary to the hepatitis C virus...
  50. ncbi [The relationship between nm23-H1 loss of heterozygosity and metastasis in hepatocellular carcinoma]
    Y Ye
    Liver Cancer Institute, Shanghai Medical University, Shanghai 200032
    Zhonghua Wai Ke Za Zhi 36:161-3. 1998
    ..between nm23-H1 loss of heterozygosity (LOH) and clinical pathological characteristics of hepatocellular carcinoma (HCC) from the DNA level...
  51. ncbi [Epigallocatechin-3-gallate induces apoptosis in human hepatocellular carcinoma cells]
    Xi Lin Chen
    Department of Hepatobiliary Surgery, First Affiliated Hospital of Sun Yat sen University, Guangzhou 510080, China
    Zhonghua Yi Xue Za Zhi 88:2524-8. 2008
    To investigate the effects of epigallocatechin-3-gallate (EGCG) on human hepatocellular carcinoma (HCC) cells and mechanism thereof.
  52. ncbi [Clinical impact of gamma-glutamyl transpeptidase messenger RNA subtypes on early diagnosis of hepatocellular carcinoma]
    Guo Qing Han
    Shandong Provincial Hospital, Jinan 250021, P R China
    Ai Zheng 21:192-5. 2002
    It has been reported that hepatocellular carcinoma (HCC) expresses gamma-glutamyl transpeptidase (GGT) with unique carbohydrate moieties compared with normal liver GGT enzymes, this unique GGT was used as a marker for the diagnosis of ..
  53. pmc Biological characteristics of HCC by ultrasound-guided aspiration biopsy and its clinical application
    Li Wu Lin
    Fujian Provincial Ultrasonic Medicine Institute, Ultrasound Department, Union Hospital of Fujian Medical University, Fuzhou, China
    World J Gastroenterol 9:941-5. 2003
    To probe the pathological biological characteristics of hepatocellular carcinoma (HCC) by the ultrasound-guided aspiration biopsy and assess the clinical application value of this method.
  54. pmc Study on hepatocellular carcinoma-associated hepatic arteriovenous shunt using multidetector CT
    Ming Yue Luo
    Department of Radiology, The Third Affiliated Hospital, Sun Yat Sen University, Guangzhou 510630, Guangdong Province, China
    World J Gastroenterol 9:2455-9. 2003
    To investigate multidetector CT (MDCT) findings of hepatocelluar carcinoma (HCC)- associated hepatic arteriovenous shunt (HAVS) and to evaluate their clinical significance.
  55. ncbi Circulating AFP mRNA as a Possible Indicator of Hematogenous Spread of HCC Cells: A Possible Association with HBV Infection
    Laila M Montaser
    The Departments of Clinical Pathology, Faculty of Medicine, Menofeya University
    J Egypt Natl Canc Inst 19:48-60. 2007
    ..Circulating alpha fetoprotein messenger RNA (AFP mRNA) has been proposed as a marker of hepatocellular carcinoma (HCC) cells disseminated into the circulation...
  56. doi Polymorphism in xeroderma pigmentosum complementation group C codon 939 and aflatoxin B1-related hepatocellular carcinoma in the Guangxi population
    Xi Dai Long
    Department of Pathology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Hepatology 52:1301-9. 2010
    ..in DNA repair capacity, and this may be associated with the risk and outcome of hepatocellular carcinoma (HCC) related to aflatoxin B1 (AFB1) exposure...
  57. ncbi Referrals for surgical therapy in patients with hepatocellular carcinoma: a community experience
    Thomas S Helling
    Department of Surgery, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    J Gastrointest Surg 11:76-81. 2007
    The treatment of hepatocellular carcinoma (HCC) is notoriously difficult. Either because of oncogenic behavior or the frequent association of cirrhosis, successful therapy is elusive, particularly in cirrhotic patients...
  58. ncbi Role of FDG-PET in the evaluation and staging of hepatocellular carcinoma with comparison of tumor size, AFP level, and histologic grade
    R M Wolfort
    Department of Surgery, Hepatobiliary and Liver Transplant Surgery, PET Imaging Center of Northwest Louisiana, Shreveport, Louisiana, USA
    Int Surg 95:67-75. 2010
    ..The potential use of FDG-PET in the evaluation and management of hepatocellular carcinoma (HCC) continues to evolve...
  59. pmc Thrombocytosis: a paraneoplastic syndrome in patients with hepatocellular carcinoma
    Shinn Jang Hwang
    Departmetn of Family Medicine, Taipei Veterans General Hospital and National Yang Ming Univerity School of Medicine, Taiwan, China
    World J Gastroenterol 10:2472-7. 2004
    Hepatocellular carcinoma (HCC) patients manifest a variety of paraneoplastic syndromes. Thrombocytosis was reported in children with hepatoblastoma...
  60. pmc Hepatocellular carcinoma prevention: a worldwide emergence between the opulence of developed countries and the economic constraints of developing nations
    Francesca Lodato
    Dipartimento di Medicina Interna e Gastroenterologia, UO di Gastroenterologia, Via Massarenti 9, Bologna 40138, Italy
    World J Gastroenterol 12:7239-49. 2006
    Hepatocellular carcinoma (HCC) is the fifth most common neoplasm, the major cause of death in patients with liver cirrhosis, and the third most common cause of cancer-related death in the world...
  61. ncbi Gene deletion of glutathione S-transferase M1 and T1 and risk factors of hepatocellular carcinoma in Egyptian patients
    Elhamy Abd El-Moneim
    Department of Clinical Pathology, National Liver Institute, Menoufiya University, Egypt
    Egypt J Immunol 15:125-34. 2008
    ..the risks-associated with GSTT1 and GSTM1 gene polymorphisms and hepatitis virus-related hepatocellular carcinoma (HCC) in an Egyptian population...
  62. ncbi Susceptibility to aflatoxin B1-related primary hepatocellular carcinoma in mice and humans
    Katherine A McGlynn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Res 63:4594-601. 2003
    ..to understand the genetic basis of aflatoxin B(1) (AFB(1))-related susceptibility to hepatocellular carcinoma (HCC). Ingestion of AFB(1) is a major risk factor for HCC in many areas of the world where HCC is common...
  63. ncbi Impairment of clathrin-mediated endocytosis via cytoskeletal change by epithelial to fibroblastoid conversion in HepG2 cells: a possible mechanism of des-gamma-carboxy prothrombin production in hepatocellular carcinoma
    Kazumoto Murata
    Center for Community Medicine, Jichi Medical University, Shimotsuke, Tochigi 329 0498, Japan
    Int J Oncol 33:1149-55. 2008
    Des-gamma-carboxy prothrombin (DCP) has been well established as a hepatocellular carcinoma (HCC) tumor marker. However, the precise mechanism by which HCC cells produce DCP remains unknown. Importantly, DCP is not specific for HCC...
  64. ncbi Clinical usefulness of computed tomography arteriography and computed tomography during arterial portography for the diagnosis of early and early advanced hepatocellular carcinoma
    T Ichikawa
    Department of Radiology, Tama Nagayama Hospital, Nippon Medical School, Tokyo, Japan
    J Nippon Med Sch 67:105-9. 2000
    ..arteriography (CTA) and CT during arterial portography (CTAP), for the diagnosis of early hepatocellular carcinoma (HCC) and early advanced HCC...
  65. ncbi Hepatic steatosis is associated with increased frequency of hepatocellular carcinoma in patients with hepatitis C-related cirrhosis
    Joel R Pekow
    Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 109:2490-6. 2007
    ..The authors sought to determine whether hepatic steatosis is associated with hepatocellular carcinoma (HCC) in a cohort of patients with hepatitis C-related cirrhosis.
  66. doi Is liver resection justified in advanced hepatocellular carcinoma? Results of an observational study in 464 patients
    Andrea Ruzzenente
    Department of Surgery and Gastroenterology, Division of General Surgery A, GB Rossi University Hospital, University of Verona Medical School, Piazzale LA Scuro 10, 37134, Verona, Italy
    J Gastrointest Surg 13:1313-20. 2009
    ..The aim of this study is to evaluate the role of surgical resection compared to other therapeutic modalities in patients with advanced hepatocellular carcinoma (HCC).
  67. ncbi Percutaneous alcohol injection of portal thrombosis in hepatocellular carcinoma: a new possible treatment
    T Livraghi
    Servizio di Radiologia, Ospedale Civile, Vimercate, Milano, Italy
    Tumori 76:394-7. 1990
    Hepatocellular carcinoma (HCC) with portal thrombosis is usually regarded as a contraindication for surgery and for percutaneous alcohol injection (PAI)...
  68. ncbi Clinical evaluation of lentil lectin-reactive alpha-fetoprotein-L3 in histology-proven hepatocellular carcinoma
    V V Khien
    Department of Hepatology, Central Tran Hung Dao Hospital, Hanoi, Vietnam
    Int J Biol Markers 16:105-11. 2001
    Serum alpha-fetoprotein (AFP) is a useful marker of hepatocellular carcinoma (HCC), although the serum AFP concentration is also increased in patients with chronic liver diseases (CLD)...
  69. ncbi Hepatocyte antigen as a marker of hepatocellular carcinoma: an immunohistochemical comparison to carcinoembryonic antigen, CD10, and alpha-fetoprotein
    Peiguo G Chu
    Department of Pathology, City of Hope National Medical Center, Duarte, California, USA
    Am J Surg Pathol 26:978-88. 2002
    ..Hep Par 1 for Hep paraffin 1) has been reported to stain normal hepatic tissue and hepatocellular carcinoma (HCC) with high specificity...
  70. ncbi Immunohistochemical expression of pi class glutathione S-transferase and alpha-fetoprotein in hepatocellular carcinoma and chronic liver disease
    Yasmin Anum Mohd Yusof
    Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia
    Anal Quant Cytol Histol 25:332-8. 2003
    To determine whether tumor marker pi glutathione transferase (GST-pi) is expressed in hepatocellular carcinoma (HCC) and other chronic liver diseases and to compare its expression with that of alpha-fetoprotein (AFP).
  71. ncbi [Correlation of somatostatin receptor expression in human hepatocellular carcinoma tissue to serum alpha-fetoprotein concentration]
    Yong mei Xie
    Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, P R China
    Ai Zheng 26:688-92. 2007
    Somatostatin analogue (SSTA) has inhibitory effect on the growth of hepatocellular carcinoma (HCC)...
  72. ncbi Cyclin dependent kinase inhibitor p27(kip1) expression and subcellular localization in relation to cell proliferation in hepatocellualr carcinoma
    Mona A H Shehata
    Department of Tropical Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt
    Egypt J Immunol 13:115-30. 2006
    Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide, with a recently increased incidence in Egypt. Its prognosis is still poor although many advances in its clinical study...
  73. doi Meta-analysis: reduced incidence of hepatocellular carcinoma in patients not responding to interferon therapy of chronic hepatitis C
    Yasuhiro Miyake
    Department of Molecular Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan
    Int J Cancer 127:989-96. 2010
    Interferon treatment for chronic hepatitis C reduces the incidence of hepatocellular carcinoma (HCC) in sustained responders...
  74. ncbi [Experimental hepatocarcinogenesis--evaluation of the significance of theoretical models. Contemporary models]
    M Marszałek
    Instytut Biofizyki, Uniwersytetu Lódzkiego w Lodzi
    Postepy Hig Med Dosw 54:67-82. 2000
    ..models are useful in identification and analysis of the preneoplastic and neoplastic alterations, as well HCC. This article presents a review of theoretical foundation and mechanisms of various models of experimental ..
  75. ncbi Types and patterns of contrast enhancement of hepatic tumours (hepatoma, hemangioma and metastasis) with dynamic computed tomography
    A Drop
    1st Department of Clinical Radiology, Medical University of Lublin
    Ann Univ Mariae Curie Sklodowska Med 56:348-56. 2001
    ..computed tomography (d-CT) of the liver was performed in 69 patients with histopathologic findings of hepatoma (HCC), 62 patients with hemangioma and in 78 patients with proved 134 liver metastases...
  76. ncbi Current treatment for hepatocellular carcinoma
    Bridget A Cahill
    Department of Medicine, Northwestern Medical Faculty Foundation, Chicago, IL, USA
    Clin J Oncol Nurs 8:393-9. 2004
    Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. In the United States, the incidence of HCC has increased by nearly 75% since the 1980s...
  77. doi Laparoscopic liver resection for hepatocellular carcinoma: ten-year experience in a single center
    Eric C H Lai
    Department of Surgery, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Rd, Chai Wan, Hong Kong SAR, China
    Arch Surg 144:143-7; discussion 148. 2009
    Laparoscopic hepatectomy and open hepatectomy for hepatocellular carcinoma (HCC) have the same surgical outcome.
  78. doi Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma
    Eri Arai
    Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
    Int J Cancer 125:2854-62. 2009
    ..at the precancerous stage, showing DNA methylation alterations that were correlated with the future development of HCC. Using Wilcoxon test, 25 BAC clones, whose DNA methylation status was inherited by HCCs from N and were able to ..
  79. doi Efficacy of double arterial phase dynamic magnetic resonance imaging with the sensitivity encoding technique versus dynamic multidetector-row helical computed tomography for detecting hypervascular hepatocellular carcinoma
    Seishi Kumano
    Department of Radiology, Kinki University School of Medicine, 377 2 Ohno Higashi, Osakasayama 589 8511, Japan
    Jpn J Radiol 27:229-36. 2009
    ..with the sensitivity encoding technique (SENSE dynamic MRI) for detection of hypervascular hepatocellular carcinoma (HCC) in comparison with double arterial phase dynamic multidetector-row helical computed tomography (dynamic MDCT).
  80. doi An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3' untranslated region confers risk for hepatocellular carcinoma
    Yuzhen Gao
    Laboratory of Cellular and Molecular Tumor Immunology, Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, Medical College, Soochow University, Suzhou 215123, Jiangsu, People s Repubic of China
    Carcinogenesis 30:2064-9. 2009
    Hepatocellular carcinoma (HCC) is the fifth most common malignancy caused by environmental and genetic factors. MicroRNAs (miRNAs) are a class of short non-coding RNAs with posttranscriptional regulatory functions...
  81. doi Clinical advantage of highly sensitive on-chip immunoassay for fucosylated fraction of alpha-fetoprotein in patients with hepatocellular carcinoma
    Yasushi Tamura
    Division of Gastroenterology and Hepatology, Niigata University Graduate School of Medical and Dental Sciences, 757 Asahimachi Dori 1 Bancho, Chuo Ku, Niigata 951 8520, Japan
    Dig Dis Sci 55:3576-83. 2010
    Alpha-fetoprotein (AFP) has been widely used as a diagnostic master for hepatocellular carcinoma (HCC), and the fucosylated fraction of AFP (AFP-L3) has been reported to be a specific marker for HCC...
  82. ncbi Octreotide therapy for hepatocellular carcinoma: a systematic review of the evidence from randomized controlled trials
    Wei Dong Jia
    Centre for the Study of Liver Cancer and Department of Hepatic Surgery, Anhui Provincial Hospital, Anhui Medical University, Hefei, Anhui, People s Republic of China
    Hepatogastroenterology 57:292-9. 2010
    Currently no standard treatment for patients with advanced hepatocellular carcinoma (HCC), and available literature assessing octreotide's treatment effect on HCC reports discordant results...
  83. doi Combination of interferon-α and 5-fluorouracil induces apoptosis through mitochondrial pathway in hepatocellular carcinoma in vitro
    Haipeng Yin
    Institute of Basic Medical Sciences, Qi Lu Hospital, Shandong University, Jinan, PR China
    Cancer Lett 306:34-42. 2011
    ..therapy of interferon-alpha plus 5-fluorouracil is remarkably effective for advanced hepatocellular carcinoma (HCC). However, the mechanism of this therapy is not well understood...
  84. ncbi [Therapy of hepatitis C: individualized approach to treatment]
    Krzysztof Simon
    Katedra i Klinika Chorób Zakaźnych, Chorób Watroby i Nabytych Niedoborów Odpornościowych Akademii Medycznej we Wrocławiu
    Przegl Epidemiol 65:21-5. 2011
    ..70% of HCV infection fail to resolve spontaneously and progress to chronic hepatitis C, eventually to cirrhosis and HCC. Many studies have demonstrated that clinical manifestation and the outcome of HCV infection are negatively ..
  85. ncbi Distinctions between clinicopathological factors and prognosis of alpha-fetoprotein negative and positive hepatocelluar carcinoma patients
    Jia Xu
    Department of Hepatobiliary Surgery, the First Affiliated Hospital of Medical College, Xi an Jiaotong University, Xi an, China
    Asian Pac J Cancer Prev 13:559-62. 2012
    ..AFP) is a significant marker for clinical diagnosis and prognosis evaluation in hepatocellular carcinoma (HCC) patients. However, some proportion of liver cancer patients are AFP-negative (AFP ≤20 ng/ml)...
  86. pmc Incidence of hepatocellular carcinoma among US patients with cirrhosis of viral or nonviral etiologies
    Robert D Mair
    Stanford University School of Medicine, Stanford, CA, USA
    Clin Gastroenterol Hepatol 10:1412-7. 2012
    We aimed to identify risk factors for hepatocellular carcinoma (HCC) in patients with cirrhosis in the United States...
  87. doi Cellular and molecular mechanisms of hepatocellular carcinoma: an update
    Rajagopal N Aravalli
    Department of Radiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Arch Toxicol 87:227-47. 2013
    Hepatocellular carcinoma (HCC) is the most common primary malignant tumor that accounts for ~80 % of all liver cancer cases worldwide...
  88. pmc Micronutrient Synergy in the Fight against Hepatocellular Carcinoma
    M Waheed Roomi
    Dr Rath Research Institute, 1260 Memorex Drive, Santa Clara, CA 95050, USA
    Cancers (Basel) 4:323-39. 2012
    The incidence of hepatocellular carcinoma (HCC), once thought to be a rare tumor in North America, has rapidly increased in recent years in the United States...
  89. doi MiR-612 suppresses the stemness of liver cancer via Wnt/β-catenin signaling
    Jun Tang
    Liver Cancer Institute and Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai 200032, China
    Biochem Biophys Res Commun 447:210-5. 2014
    ..has inhibitory effects on cell proliferation, migration, invasion, and metastasis of hepatocellular carcinoma (HCC)...
  90. doi Lactobionic acid coupled liposomes: an innovative strategy for targeting hepatocellular carcinoma
    Divya Bansal
    a Pharmaceutics Research Laboratory, Shri Ram Institute of Technology Pharmacy, Jabalpur, Madhya Pradesh, India and
    Drug Deliv 23:140-6. 2016
    Liver cancer or hepatocellular carcinoma (HCC) is a major cause of death worldwide. Targeted delivery of drug to the carcinoma cell can be achieved by conjugation of ligand on the carrier system.
  91. doi Assessment and monitoring of liver function by ¹³C-aminopyrine breath test after selective transarterial chemoembolisation of hepatocellular carcinoma
    K Schutte
    Klinik fur Gastroenterologie, Hepatologie and Infektiologie, Universitätsklinikum Magdeburg A ö R
    Z Gastroenterol 53:21-7. 2015
    ..staging are essential parameters for selection of treatment modalities in patients with hepatocellular carcinoma (HCC). Transarterial chemoembolization (TACE) is associated with a risk of deterioration of liver function...
  92. pmc Survival Analysis of Hepatocellular Carcinoma: A Comparison Between Young Patients and Aged Patients
    Xin Sen Xu
    Department of Hepatobiliary Surgery, the First Affiliated Hospital of Medical College, Xi an Jiaotong University, Xi an, Shannxi 710061, China
    Chin Med J (Engl) 128:1793-800. 2015
    To compare the clinicopathological features and prognosis between younger and aged patients with hepatocellular carcinoma (HCC).
  93. pmc Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells
    Jiayi Wang
    Department of Clinical Laboratory Medicine, Shanghai Tenth People s Hospital of Tongji University, Shanghai, China
    Oncotarget 6:24075-91. 2015
    Doxorubicin (Doxo) is one of the most widely used chemotherapeutic drugs for patients with hepatocellular carcinoma (HCC). Doxo is a DNA intercalating drug that inhibits topoisomerase II...
  94. doi AGXT2L1 is down-regulated in heptocellular carcinoma and associated with abnormal lipogenesis
    Qianshan Ding
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China
    J Clin Pathol 69:215-20. 2016
    To clarify the clinical implications and functional role of the alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1) gene in hepatocellular carcinoma (HCC).
  95. pmc Urinary nuclear magnetic resonance spectroscopy of a Bangladeshi cohort with hepatitis-B hepatocellular carcinoma: A biomarker corroboration study
    I Jane Cox
    I Jane Cox, Antonio Riva, Roger Williams, Institute of Hepatology, London, Foundation for Liver Research, London WC1E 6HX, United Kingdom
    World J Gastroenterol 22:4191-200. 2016
    To establish if a distinct urinary metabolic profile could be identified in Bangladeshi hepatitis-B hepatocellular carcinoma (HCC) patients compared to cirrhosis patients and controls.
  96. pmc KLHL21, a novel gene that contributes to the progression of hepatocellular carcinoma
    Lei Shi
    School of Life Sciences, Chongqing University, Chongqing, 400044, People s Republic of China
    BMC Cancer 16:815. 2016
    Hepatocellular carcinoma (HCC) has very high prevalence and associated-mortality...
  97. ncbi Clinical benefit of peretinoin for the suppression of hepatocellular carcinoma (HCC) recurrence in patients with Child-Pugh grade A (CP-A) and small tumor: A subgroup analysis in a phase II/III randomized, placebo-controlled trial
    T Okusaka
    Division of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Tokyo, Japan Japanese Red Cross Medical Center, Tokyo, Japan Kanazawa University, Ishikawa, Japan Toranomon Hospital, Tokyo, Japan Yokohama City University Medical Center, Yokohama, Japan Gifu University, Gifu, Japan Musashino Red Cross Hospital, Tokyo, Japan Department of Biostatistics, School of Public Health, University of Tokyo, Tokyo, Japan Shimonoseki Kohsei Hospital, Yamaguchi, Japan
    J Clin Oncol 29:165. 2011
    165 Background: HCC has a high recurrence rate and poor prognosis; however, no effective treatment has been established for preventing recurrence after resection or ablation...
  98. ncbi Polymorphisms of microsomal epoxide hydrolase gene and severity of HCV-related liver disease
    Laura Sonzogni
    Associazione Studi Avanzati Epatiti Virali ASAEV, Bonate Sotto BG, Italy
    Hepatology 36:195-201. 2002
    Factors influencing the progression of liver disease and the development of hepatocellular carcinoma (HCC) in chronic hepatitis C virus (HCV) infection are poorly understood...
  99. ncbi Measurement of des-gamma-carboxy prothrombin levels in hemodialysis patients positive for anti-hepatitis virus C antibody
    A Kato
    First Department of Medicine, Hamamatsu University School of Medicine, Shizuoka, Japan
    Clin Nephrol 58:296-300. 2002
    ..PIVKA-II) has been demonstrated as a sensitive marker for the early detection of hepatocellular carcinoma (HCC)...
  100. ncbi Future of molecular profiling of human hepatocellular carcinoma
    Stephanie Roessler
    National Cancer Institute, Laboratory of Human Carcinogenesis, Center for Cancer Research, NIH, 37 Convent Drive, Bldg 37, Rm 3044A, Bethesda, MD 20892 4258, USA
    Future Oncol 3:429-39. 2007
    Hepatocellular carcinoma (HCC) is a fatal disease occurring worldwide and developing mainly in chronic liver diseased patients...
  101. doi Comparison of the outcomes between an anatomical subsegmentectomy and a non-anatomical minor hepatectomy for single hepatocellular carcinomas based on a Japanese nationwide survey
    Susumu Eguchi
    Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Surgery 143:469-75. 2008
    Although a surgical resection is an important modality for the treatment of hepatocellular carcinoma (HCC), the impact of the operative method on both the patient survival and disease-free survival (DFS) still remains controversial.

Research Grants122 found, 100 shown here

  1. Integrating plasma IGF-1 into novel classification of hepatocellular carcinoma
    Ahmed Kaseb; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): In hepatocellular carcinoma (HCC) management, the Child-Pugh (CP) score is the current standard tool for assessing the underlying chronic liver disease (CLD) status in clinical practice and ..
  2. Molecular Epidemiology of Chronic Liver Diseases
    Manal Hassan; Fiscal Year: 2009
    ..Steven Curley (co-mentor) will provide guidance in the clinical features of hepatocellular carcinoma (HCC);and Dr...
  3. Dysregulation of the Tumor Microenvironment in Hepatocellular Carcinoma
    Lewis R Roberts; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. The stromal changes underlying the development and progression of HCC are important but incompletely understood...
  4. Yujin Hoshida; Fiscal Year: 2016
    DESCRIPTION (provided by applicant): The accelerating incidence and dismal mortality of hepatocellular carcinoma (HCC) (5-yr survival <12%) highlight the urgent need to improve prediction and prevention of this deadly neoplasm...
  5. In-situ Gelling Protein Polymer Intravascular Embolic Agent for Hepatic Carcinoma
    Hamid Ghandehari; Fiscal Year: 2012
    ..Because of the lack of symptoms, hepatocellular carcinoma (HCC) is detected at advanced stages in 84% of cases, for which the 1-year survival rate is 22% and at 5 years it is 5%...
  6. SAMUEL WHEELER FRENCH; Fiscal Year: 2015
    ..8% of the population and appears to be the major etiologic factor responsible for the recent doubling of HCC in the United States. Current therapy consists of pegylated interferon-1 (PEG-IFN) and ribavirin (RBV)...
  7. Transgenic mouse models of HCV infection and replication
    Jieyun Jiang; Fiscal Year: 2012
    ..Hepatitis C virus (HCV) is the leading cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). HCV chronically infects approximately 4 million people in the U.S. and 170 million people worldwide...
  8. GUANGXIANG GEORGE LUO; Fiscal Year: 2016
    ..HCV is also the major cause of hepatocellular carcinoma (HCC), the most rapidly increasing cancer with more than 14,000 deaths each year in the U.S...
  9. Pathogenesis and Treatment of Liver Disease in Transaldolase Deficiency
    Andras Perl; Fiscal Year: 2013
    ..both acute acetaminophen-induced liver failure and chronic liver diseases, cirrhosis and hepatocellular carcinoma (HCC), no common underlying metabolic pathways have been identified...
  10. Combination therapies for chronic HBV, liver disease and cancer
    Mark A Feitelson; Fiscal Year: 2012
    ..at high risk for the development of hepatitis, cirrhosis (end stage liver disease) and hepatocellular carcinoma (HCC)...
  11. Serum Biomarkers Associated With Phenotypic Expression of Hemochromatosis.
    Kris Kowdley; Fiscal Year: 2013
    ..of many circulating serum miRNA are elevated in patients with a variety of liver diseases and pathologies including HCC, HBV and liver cirrhosis, therefore serum miRNAs represent a new type of diagnostic and prognostic biomarker, and ..
  12. DAVID ANDREW LARGAESPADA; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): The development of hepatocellular carcinoma (HCC) is a serious and feared malignancy, which is increasing in prevalence in the United States...
  13. Radoslav Goldman; Fiscal Year: 2016
    DESCRIPTION (provided by applicant): This proposal aims to detect hepatocellular carcinoma (HCC) at a treatable stage by non-invasive methods...
  14. J H James Ou; Fiscal Year: 2015
    ..cause severe liver diseases including acute and chronic hepatitis, liver cirrhosis and hepatocellular carcinoma (HCC)...
  15. SIGNIFICANCE OF GGT EXPRESSION IN TUMORS
    MARIE HANIGAN; Fiscal Year: 2009
    ..multiple, large cohort studies over the past thirty years have shown that patients with hepatocellular carcinoma (HCC) have tumor-specific isoforms of GGT in their serum that can be resolved on native polyacrylamide gels...
  16. David M Lubman; Fiscal Year: 2016
    DESCRIPTION (provided by applicant): Hepatocellular Carcinoma (HCC) is the fourth most common cancer in the world...
  17. Anand S Mehta; Fiscal Year: 2016
    ..along with others, have shown increased levels of fucosylation with the development of hepatocellular carcinoma (HCC)...
  18. Jianying Zhang; Fiscal Year: 2014
    ..In the case of liver cancer, especially hepatocellular carcinoma (HCC), antecedent liver cirrhosis and chronic hepatitis are common precursor conditions and during transition to ..
  19. IKKbeta:Bi-Functional Regulator of Hepatocyte Proliferation
    Hyam L Leffert; Fiscal Year: 2010
    ..mouse liver regeneration starts faster and the diethylnitrosamine- induced incidence of hepatocellular carcinoma (HCC) is higher in mice carrying targeted hepatocyte-specific IKK[unreadable] deletions...
  20. Do barriers to transplantation impact liver cancer survival in Asians?
    Umut Sarpel; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the third leading cause of death from cancer worldwide...
  21. Hanna K Sanoff; Fiscal Year: 2015
    ..UVA's academic excellence in liver transplantation and hepatocellular carcinoma (HCC) are ideally suited to support the proposed research project...
  22. Adrian Cotterell; Fiscal Year: 2014
    ..VCU leads the way in Hepatocellular Carcinoma (HCC) data and sample repository collection for HCC in liver transplantation...
  23. Long Term Outcome for Liver Transplantation for Hepatocellular Carcinoma
    Richard B Freeman; Fiscal Year: 2010
    ..transplantation (LT) has evolved as the treatment of choice for patients with early stage hepatocellular carcinoma (HCC) and underlying cirrhosis of the liver...
  24. Tumor-targeted anti-CK2 RNAi for treatment of HCC
    Betsy T Kren; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is a rapidly increasing form of cancer in the United States, with ~ 14,000 deaths annually, ranking it as the 8th cause of cancer mortality...
  25. A novel diagnostic biomarker for hepatocellular carcinoma and cholangiocarcinoma
    Xuanyong Lu; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) and intrahepatic cholagiocarcinoma (ICC) usually go undetected until its late stages, with a 5-year survival rate less than 10%...
  26. Michael Karin; Fiscal Year: 2016
    ..identification and isolation of pre-neoplastic cells that serve as precursors for hepatocellular carcinoma (HCC) in mice...
  27. Development of a Urine Test for the Early Detection of Liver Cancer
    Wei Song; Fiscal Year: 2012
    ..by applicant): The need to develop an effective method of detecting primary and recurrent hepatocellular carcinoma (HCC) is urgent. HCC is the third leading cause of cancer deaths and has a 5-year survival rate of less than 10%...
  28. MingDe Lin; Fiscal Year: 2015
    ..Liver cancer is one of the most common cancers worldwide with >500,000 new cases/yr of hepatocellular carcinoma (HCC, primary liver cancer) and >200,000 new cases/yr of liver dominant colorectal cancer metastases (secondary liver ..
  29. Mehmet Toner; Fiscal Year: 2014
    ..antibody-coated microfluidic surface-capture device, the Herringbone CTC-chip, to isolate hepatocellular carcinoma (HCC) circulating tumor cells (CTCs) from venous blood...
  30. Surbhi Jain; Fiscal Year: 2015
    ..The need to develop an effective method of detecting hepatocellular carcinoma (HCC) is urgent. HCC is the third leading cause of cancer deaths and has a 5-year survival rate of less than 15%...
  31. Iron-Induced Changes in Liver That Predispose to Malignancy
    Harriet C Isom; Fiscal Year: 2010
    Hepatocellular carcinoma (HCC) is one of the most common causes of cancer death and is on the rise in the United States. Preventative strategies are highly important in reducing the incidence and death from HCC...
  32. Aberrant DNA Methylation of MicroRNA Genes in Hepatocellular Carcinoma (HCC)
    Jing Shen; Fiscal Year: 2012
    ..by promoter DNA methylation is an important mechanism of tumorigenesis, including in hepatocellular carcinoma (HCC)...
  33. Jinah Choi; Fiscal Year: 2015
    DESCRIPTION (provided by applicant): Hepatitis C virus is a major etiologic agent of hepatocellular carcinoma (HCC). HCV-induced HCC is typically preceded by chronic hepatitis and cirrhosis...
  34. HCV Strain Variation and HCC
    Andrea D Branch; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related mortality in the world...
  35. Regulation of HBV Replication by the Immune System
    Luca G Guidotti; Fiscal Year: 2012
    ..Hepatitis B virus (HBV) causes acute and chronic necroinflammatory liver disease and hepatocellular carcinoma (HCC)...
  36. Lishan Su; Fiscal Year: 2016
    ..by applicant): Chronic hepatitis C virus (HCV) infection is now the leading cause of hepatocellular carcinoma (HCC), a highly lethal cancer with rapidly increasing incidence in the U.S...
  37. HCV in Alcoholics
    Jack R Wands; Fiscal Year: 2011
    Chronic hepatitis C (HCV) infection is a major cause of liver disease, cirrhosis, and hepatocellular carcinoma (HCC) in alcoholics...
  38. NATURAL HISTORY PREVENTION OF VIRAL HEPATITIS IN ALASKA NATIVE PEOPLE
    BRIAN JAMES MCMAHON; Fiscal Year: 2012
    ..hepatitis B and C infections are significant causes of morbidity and mortality from hepatocellular carcinoma (HCC) and cirrhosis in high risk populations in the US...
  39. Forms of HCV NS5A in vivo
    Craig E Cameron; Fiscal Year: 2013
    ..by this virus to establish persistence, which can ultimately lead to the development of hepatocellular carcinoma (HCC). HCV non-structural protein 5A (NS5A) is unique among non-structural proteins of most positive-strand RNA viruses...
  40. Synergistic innate immune activation and cell killing by RIG-I ligands in HCV-HCC
    Lee Gehrke; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is an unfortunate and predictable consequence of hepatitis C virus (HCV) infections, defining it as a significant global human heath problem...
  41. Hashem B El-Serag; Fiscal Year: 2016
    ..epidemiology and outcomes of Barrett's esophagus (BE), hepatitis C virus (HCV) and hepatocellular carcinoma (HCC)...
  42. Hepatitis C Clinical Trial-Clinical Center
    Jules L Dienstag; Fiscal Year: 2009
    ..respond to antiviral treatment are at risk of progression to cirrhosis, liver failure, hepatocellular carcinoma (HCC) and death...
  43. Nanog-positive cancer stem cells in and liver oncogenesis by alcohol and HCV
    Keigo Machida; Fiscal Year: 2013
    ..identifies a synergism between alcohol and HCV infection for the risk of developing hepatocellular carcinoma (HCC)...
  44. Directed Evolution of a Murine Model of Hepatitis C Virus Replication
    PRISCILLA LI NING YANG; Fiscal Year: 2010
    ..HCV causes acute and chronic hepatitis and is the leading cause of hepatocellular carcinoma (HCC) in the United States...
  45. Amino Acid Transporters ASCT2 and LAT1 in Human Hepatocellular Cancer Growth
    BARRIE BODE; Fiscal Year: 2009
    ..aims to examine the efficacy of targeting amino acid transporters ASCT2 and LAT1 in human hepatocellular carcinoma (HCC), a recalcitrant cancer with poor prognosis and limited treatment options...
  46. Markers for HCV-related HCC: plasma profiling, targeted strategies and validation
    Laura Beretta; Fiscal Year: 2013
    A trend of increasing rates of hepatocellular carcinoma (HCC) has been reported worldwide, that is related to the high prevalence of hepatitis C virus (HCV) infection in the population. Better means for HCC diagnosis are urgently needed...
  47. Roles for RCK/DDX6 in hepatitis C virus pathogenesis and hepatocellular carcinoma
    Peter Sarnow; Fiscal Year: 2010
    Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths...
  48. Keith D Robertson; Fiscal Year: 2015
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the 5th most common cancer worldwide, causing an estimated 600,000 deaths/yr...
  49. Alexander Ploss; Fiscal Year: 2016
    ..chronic HCV carriers can develop severe liver disease including fibrosis, cirrhosis and hepatocellular carcinoma (HCC). Antiviral treatment is only partially effective, costly and often poorly tolerated...
  50. Novel viral element in pathogen recognition receptor signaling by hepatitis C vir
    Jinah Choi; Fiscal Year: 2010
    ..in chronic infection that can lead to severe liver diseases, including cirrhosis and hepatocellular carcinoma (HCC)...
  51. Guideline-based surveillance and treatment of hepatocellular carcinoma
    Jessica A Davila; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the fastest rising cause of cancer-related deaths...
  52. MICHAEL CYRUS MAHER; Fiscal Year: 2014
    ..g. Patel et al., 2012);HCV+ hepatocellular carcinoma (HCC) sequencing data (Fujimoto et al...
  53. Novel Reagents For The Detection Of Low Abundance Cancer Specific Glycoforms
    MICHAEL JOHN CIOCCI; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is one of the most common solid malignancies worldwide and the incidence in the United States is increasing...
  54. HOLLY C HAGAN; Fiscal Year: 2016
    ..20-25% wil develop liver disease which may manifest as cirrhosis, liver failure or hepatocellular carcinoma (HCC). The prognosis for HCC is extremely poor, and HCV is the chief etiologic agent for this type of cancer...
  55. Role of SAMe on UBC9 and sumolyation in liver cancer and alcoholic liver injury
    Maria Lauda Tomasi; Fiscal Year: 2012
    ..Whether UBC9 is deregulated in hepatocellular carcinoma (HCC) is unknown. How UBC9 protein stability is regulated post-translationally is also unknown...
  56. Bayar Thimmapaya; Fiscal Year: 2016
    ..Med1 also controls liver regeneration and the development of hepatocellular carcinoma (HCC), in that hepatocytes lacking Med1 fail to regenerate and fail to give rise to liver tumors...
  57. Nanoemulsion-based vaccine for chronic hepatitis B virus
    James R Baker; Fiscal Year: 2010
    ..leading to nearly one million deaths annually as a result of cirrhosis, liver failure and hepatocellular carcinoma (HCC)...
  58. Molecular Mechanisms of Chemoprevention: NRF2 Signaling
    Thomas W Kensler; Fiscal Year: 2013
    ..aflatoxin-induced hepatocarcinogenesis in the rat and in a murine model recapitulating major human risk factors for HCC, namely, aflatoxin exposure and infection with HBV...
  59. Ourania M Andrisani; Fiscal Year: 2015
    ..Chronic Hepatitis B Virus (HBV) infection is a major factor in the pathogenesis of hepatocellular carcinoma (HCC)...
  60. Betty L Slagle; Fiscal Year: 2014
    ..people worldwide and is a significant risk factor for severe liver disease, including hepatocellular carcinoma (HCC)...
  61. Role of microRNA-122 in hepatocarcinogenesis using conditional knock out mice
    Kalpana Ghoshal; Fiscal Year: 2013
    ..b>HCC is the fifth most common cancer and the third common cause of cancer related death...
  62. Activating liver carcinogens in yeast by expressing CYP450 polymorphisms
    MICHAEL THOMAS FASULLO; Fiscal Year: 2010
    DESCRIPTION (Provided by applicant): Hepatocellular carcinoma (HCC) has been correlated with specific p53 mutations and exposure to aflatoxin B1 (AFB1). Individual response to liver carcinogens shows great variability...
  63. Role of Polo-like kinase (Plk-1) in Hepatitis B Virus-mediated Hepatocellular Car
    Ourania M Andrisani; Fiscal Year: 2010
    Chronic Hepatitis B virus (HBV) infection is linked to hepatocellular carcinoma (HCC). The HBV X protein (pX) is implicated in HCC pathogenesis by an unknown mechanism...
  64. Lipid peroxidation product induced DNA damage in the p53 gene and liver cancer
    ERIC MOON SHONG M TANG; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is a major malignancy worldwide...
  65. Fate-mapping temporally marked precursor populations to hepatocellular carcinoma
    Hyam L Leffert; Fiscal Year: 2013
    ..long-term objectives of this application are to identify the cellular origins of hepatocellular carcinoma ('HCC')...
  66. NITROGEN HETEROCYCLES: METABOLIC EFFECTS AND TOXICITY
    Raymond F Novak; Fiscal Year: 2010
    ..Akt, mTOR signaling, in the insulin regulation of gene transcription, miRNAs and mRNA translation is critical to understanding the progression of hepatic disease culminating in HCC and the role of CYP2E1 as a biomarker of this process.
  67. GONZAGUE JOSEPH JOURDAIN; Fiscal Year: 2016
    ..Chronic HBV, complicated by cirrhosis and hepatocellular carcinoma (HCC), is the 10th leading cause of death worldwide. About 7% of Thai adults are HBsAg carriers...
  68. Genes Related to HCC Progression in LD and DD Transplant
    Robert A Fisher; Fiscal Year: 2010
    The incidence of hepatocellular carcinoma (HCC) is rising in the USA because of the increased prevalence of cirrhosis from HCV infection...
  69. Jessica Casciano; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and third highest cause of cancer-related deaths...
  70. John M Essigmann; Fiscal Year: 2015
    ..As in the human HCC incidence pattern, AFB1 is more potent in males than females, and animals of both sexes are more sensitive as ..
  71. RICHARD JASON LAMONTAGNE; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): Globally, hepatocellular carcinoma (HCC) is the sixth most common cancer. A lack of early detection methods and effective treatment options also make it one of the most deadly...
  72. miRNA Biomarkers for Hepatocellular Carcinoma Associated with Viral Hepatitis
    Thomas D Schmittgen; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the third most common cause of cancer death worldwide. HCC is among the fastest growing group of cancer deaths in the U...
  73. Prevention of EtOH-induced promotion of hepatocarcinogenesis by genistein/soy
    Martin J J Ronis; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is now the world's third leading cause of cancer mortality. Alcohol is a well known risk factor for HCC and is suggested to account for 32-45% of all HCC cases...
  74. Frank A Anania; Fiscal Year: 2016
    ..will develop liver injury from hepatic fat stores including hepatitis, cirrhosis, and hepatocellular carcinoma (HCC)...
  75. AZADEH POURSAID; Fiscal Year: 2016
    DESCRIPTION (provided by applicant): Globally, hepatocellular carcinoma (HCC) of the liver is diagnosed in over 500,000 people annually and trends indicate increasing prevalence...
  76. Herbert Yu; Fiscal Year: 2015
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is one of the most fatal malignancies in the world. Five-year survival rate of the disease is only 10%. The incidence of HCC has been steadily rising in the US...
  77. Erin Stashi; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the most common and highly lethal form of liver cancer, yet the molecular mechanisms underlying HCC pathogenesis remain poorly understood...
  78. DARYL T LAU; Fiscal Year: 2016
    ..Complications of CHB including liver failure and hepatocellular carcinoma (HCC) result in 1.2 million deaths per year, making CHB the 10th leading cause of mortality worldwide...
  79. David A Woodrum; Fiscal Year: 2016
    ..long-range objective of this proposal is to improve the prognosis for patients with hepatocellular carcinoma (HCC)...
  80. TRAM THUY TRAN; Fiscal Year: 2014
    ..Risk factors for liver failure or hepatocellular carcinoma (HCC) in HBV patients remain undefined, though recent data support virological markers (HBV DMA quantitation) as ..
  81. Yi Ping Shih; Fiscal Year: 2016
    ..the pathological progression from hepatocyte damage to inflammation, fibrosis, cirrhosis, hepatocellular carcinoma (HCC) and metastasis...
  82. Christopher L Bowlus; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is a blatant example of a cancer health disparity in that HCC is disproportionally higher in incidence and mortality among Asian Americans compared with non-Hispanic ..
  83. J H James Ou; Fiscal Year: 2016
    ..virus that can cause severe liver diseases including acute and chronic hepatitis and hepatocellular carcinoma (HCC). There are ~350 million people in the world that are chronically infected by this virus, resulting in 0...
  84. The Role of EGF in Human Hepatocellular Transformation
    BRYAN CHRISTOPHER FUCHS; Fiscal Year: 2013
    Overexpression of epidermal growth factor (EGF) in the liver induces transformation to hepatocellular carcinoma (HCC) in animal models...
  85. Xifeng Wu; Fiscal Year: 2016
    ..Point-of-Care Test of Exposure to Hepatocellular Carcinoma Risk by V-Chip Underlying mechanisms for synergisms of HCC risks may provide efficient and accurate HCC prevention strategies for high-risk individuals...
  86. Timothy Tellinghuisen; Fiscal Year: 2015
    ..worldwide and chronic virus infection in these individuals is a significant cause of hepatocellular carcinoma (HCC)...
  87. Lewis R Roberts; Fiscal Year: 2014
    ..project, we will investigate means to optimize the long term outcome in patients with HBV infection including HCC and end stage liver disease. The majority of these patients will be HBeAg-negative...
  88. Abhishek Satishchandran; Fiscal Year: 2016
    ..abstinence, 5-15% of patients with steatohepatitis still progress to cirrhosis and hepatocellular carcinoma (HCC)...
  89. Zhaohui Feng; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): Hepatocellular carcinoma (HCC) is the most rapidly increasing type of cancer with high mortality in the United States...
  90. Habtom W Ressom; Fiscal Year: 2014
    ..and statistical methods will be applied to identify peptide and glycan candidate biomarkers for early detection of HCC. This will be accomplished by using two LC-MS technologies to evaluate the expression of peptides and glycans in ..
  91. Kyong Mi Chang; Fiscal Year: 2014
    ..DMA virus that causes acute and chronic hepatitis with progression to cirrhosis and hepatocellular carcinoma (HCC)...
  92. Robert F Schwabe; Fiscal Year: 2014
    Hepatocellular carcinoma (HCC) is the fifth most common cancer causing about 500,000 deaths/year world-wide. In the US, the incidence of HCC has almost doubled over the last three decades...
  93. Alexey Wolfson; Fiscal Year: 2014
    ..steatohepatitis and cirrhosis, which can lead to other more fatal complications such as hepatocellular carcinoma (HCC)...