HIST1H2BE

Summary

Gene Symbol: HIST1H2BE
Description: histone cluster 1 H2B family member e
Alias: H2B.h, H2B/h, H2BFH, dJ221C16.8, histone H2B type 1-C/E/F/G/I, H2B histone family, member H, histone 1, H2be, histone H2B.1 A, histone H2B.h, histone cluster 1, H2be
Species: human

Top Publications

  1. ncbi Human spleen histone H2B. Isolation and amino acid sequence
    Y Ohe
    J Biochem 85:615-24. 1979
  2. ncbi Antimicrobial peptides in the first line defence of human colon mucosa
    Maria Tollin
    Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Peptides 24:523-30. 2003
  3. pmc A Role for Histone H2B Variants in Endocrine-Resistant Breast Cancer
    Shweta R Nayak
    Division of Reproductive Endocrinology, Magee Womens Hospital, University of Pittsburgh Medical Center UPMC, Pittsburgh, PA, USA
    Horm Cancer 6:214-24. 2015
  4. pmc Expressing Status and Correlation of ARID1A and Histone H2B on Breast Cancer
    Yan Wu
    Department of Surgery, The Ninth People s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, China Department of Surgery, Zhoupu Hospital of Pudong District, Shanghai, China
    Biomed Res Int 2016:7593787. 2016
  5. ncbi A novel divergently transcribed human histone H2A/H2B gene pair
    T Dobner
    Institut fur Biochemie, Ludwig Maximilians Universitat, Munchen, Germany
    DNA Seq 1:409-13. 1991
  6. ncbi Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
    Wang L Cheung
    Department of Microbiology, University of Virginia Health System, Charlottesville 22908, USA
    Cell 113:507-17. 2003
  7. ncbi Inhibition of core histones acetylation by carcinogenic nickel(II)
    Filip Golebiowski
    Laboratory of Comparative Carcinogenesis, NCI at Frederick, Frederick, MD, 21702 1201, USA
    Mol Cell Biochem 279:133-9. 2005
  8. ncbi Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation
    Bing Zhu
    Howard Hughes Medical Institute, Division of Nucleic Acids Enzymology, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 683 Hoes Lane, Piscataway, New Jersey 08854, USA
    Mol Cell 20:601-11. 2005
  9. ncbi Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry
    Debora Bonenfant
    Genome and Proteome Sciences, Novartis Institutes for BioMedical Research, CH 4056 Basel, Switzerland
    Mol Cell Proteomics 5:541-52. 2006
  10. ncbi Quantitative proteomic analysis of post-translational modifications of human histones
    Hans Christian Beck
    Danish Technological Institute, Holbergsvej 10, DK 6000 Kolding, Denmark
    Mol Cell Proteomics 5:1314-25. 2006

Scientific Experts

  • Filip Golebiowski
  • Yan Wu
  • Shweta R Nayak
  • Bing Zhu
  • Debora Bonenfant
  • Hans Christian Beck
  • Rushad Pavri
  • Danny Reinberg
  • Wang L Cheung
  • Wei Zhang
  • Yan Gu
  • Qiancheng Dai
  • Maria Tollin
  • Shanyu Guo
  • Emily Harrington
  • David Boone
  • Jian Chen
  • Ryan Hartmaier
  • Adrian V Lee
  • Steffi Oesterreich
  • Thushangi N Pathiraja
  • Kristine L Cooper
  • David Dabbs
  • Nancy E Davidson
  • Jeffrey L Fine
  • Joseph Sanfilippo
  • Subhrangsu Mandal
  • Ali Shilatifard
  • Ole Nørregaard Jensen
  • Harry Towbin
  • Jan van Oostrum
  • Michele Coulot
  • Eva C Nielsen
  • Maxwell Sehested
  • Anne Maria Hansen
  • Morten Grauslund
  • Lars H Jensen
  • Patrick Trojer
  • Guohong Li
  • Patrick Schindler
  • Paul Finn
  • Rune Matthiesen
  • Anh Dung Pham
  • Paul Tempst
  • Subhrangsu S Mandal
  • Yong Zheng
  • Hediye Erdjument-Bromage
  • Malgorzata Kloc
  • Peter Bergman
  • Alexander Beeser
  • Kozo Ajiro
  • Hans Jornvall
  • Laurence D Etkin
  • Torgny Svenberg
  • William C Earnshaw
  • C David Allis
  • Craig A Mizzen
  • Birgitta Agerberth
  • Jonathan Chernoff
  • Gudmundur Hrafn Gudmundsson
  • Kumiko Samejima
  • Peter Cheung
  • T Dobner
  • Y Ohe
  • M Lipp
  • H Hayashi
  • B Mai
  • K Iwai
  • I Wolf

Detail Information

Publications11

  1. ncbi Human spleen histone H2B. Isolation and amino acid sequence
    Y Ohe
    J Biochem 85:615-24. 1979
    ..Thus, it is concluded that the H2B sequence of lower mammals was conserved during the evolutionary process leading to man...
  2. ncbi Antimicrobial peptides in the first line defence of human colon mucosa
    Maria Tollin
    Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Peptides 24:523-30. 2003
    ..Combined, these results indicate that the colon mucosa is protected by a complex mixture of polypeptides, able to kill invading microbes and working in synergy as a barrier against bacterial invasion...
  3. pmc A Role for Histone H2B Variants in Endocrine-Resistant Breast Cancer
    Shweta R Nayak
    Division of Reproductive Endocrinology, Magee Womens Hospital, University of Pittsburgh Medical Center UPMC, Pittsburgh, PA, USA
    Horm Cancer 6:214-24. 2015
    ..Here, we show that the histone variant HIST1H2BE is hypomethylated in estrogen deprivation-resistant C4-12 and long-term estrogen-deprived (LTED) cells compared ..
  4. pmc Expressing Status and Correlation of ARID1A and Histone H2B on Breast Cancer
    Yan Wu
    Department of Surgery, The Ninth People s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, China Department of Surgery, Zhoupu Hospital of Pudong District, Shanghai, China
    Biomed Res Int 2016:7593787. 2016
    ..Histone H2B is a major component of chromatin and encoded by HIST1H2BE. The goal of the study is to evaluate expressing status of ARID1A and H2B as well as their correlation on breast ..
  5. ncbi A novel divergently transcribed human histone H2A/H2B gene pair
    T Dobner
    Institut fur Biochemie, Ludwig Maximilians Universitat, Munchen, Germany
    DNA Seq 1:409-13. 1991
    ..The spatial arrangement and orientation of two TATA-boxes, four CAAT-boxes, and one H2B-box within this region suggests that the linked genes share common promoter elements for transcriptional regulation...
  6. ncbi Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
    Wang L Cheung
    Department of Microbiology, University of Virginia Health System, Charlottesville 22908, USA
    Cell 113:507-17. 2003
    ..Our data provide evidence for a potential apoptotic "histone code."..
  7. ncbi Inhibition of core histones acetylation by carcinogenic nickel(II)
    Filip Golebiowski
    Laboratory of Comparative Carcinogenesis, NCI at Frederick, Frederick, MD, 21702 1201, USA
    Mol Cell Biochem 279:133-9. 2005
    ..The observed effects may contribute to neoplastic transformation of Ni(II)-exposed cells...
  8. ncbi Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation
    Bing Zhu
    Howard Hughes Medical Institute, Division of Nucleic Acids Enzymology, Department of Biochemistry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 683 Hoes Lane, Piscataway, New Jersey 08854, USA
    Mol Cell 20:601-11. 2005
    ..In contrast, RNAi against the RNF20/40 complex or hPAF complex reduces H2B monoubiquitination, lowers methylation levels at H3 lysines 4 and 79, and represses HOX gene expression...
  9. ncbi Characterization of histone H2A and H2B variants and their post-translational modifications by mass spectrometry
    Debora Bonenfant
    Genome and Proteome Sciences, Novartis Institutes for BioMedical Research, CH 4056 Basel, Switzerland
    Mol Cell Proteomics 5:541-52. 2006
    ..The analysis of core histone subtypes with their modifications provides a first step toward an understanding of the functional significance of the diversity of histone structures...
  10. ncbi Quantitative proteomic analysis of post-translational modifications of human histones
    Hans Christian Beck
    Danish Technological Institute, Holbergsvej 10, DK 6000 Kolding, Denmark
    Mol Cell Proteomics 5:1314-25. 2006
    ..This demonstrates that mass spectrometry-based quantitative proteomic analysis of post-translational modifications is a viable approach for functional analysis of candidate drugs, such as HDAC inhibitors...
  11. ncbi Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II
    Rushad Pavri
    Howard Hughes Medical Institute, Department of Biochemistry, Division of Nucleic Acids Enzymology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 683 Hoes Lane, Piscataway, NJ 08854, USA
    Cell 125:703-17. 2006
    ....