hevin

Summary

Gene Symbol: hevin
Description: SPARC like 1
Alias: MAST 9, MAST9, PIG33, SC1, SPARC-like protein 1, SPARC-like 1 (hevin), high endothelial venule protein, proliferation-inducing protein 33
Species: human

Top Publications

  1. ncbi [Molecular characterization of hepatitis E virus in three acute liver failure cases in children in Argentina]
    María Silvina Munné
    Laboratorio Nacional de Referencia para Hepatitis Virales, Instituto Nacional de Enfermedades Infecciosas, A N L I S C G Malbrán, Buenos Aires, Argentina
    Acta Gastroenterol Latinoam 36:125-30. 2006
  2. ncbi Matrix glycoprotein SC1/ECM2 augments B lymphopoiesis
    K Oritani
    Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA
    Blood 90:3404-13. 1997
  3. ncbi Expression of mRNA encoding extracellular matrix glycoproteins SPARC and SC1 is temporally and spatially regulated in the developing cochlea of the rat inner ear
    A J Mothe
    Department of Zoology, University of Toronto at Scarborough, M1C 1A4, Toronto, ON, Canada
    Hear Res 155:161-74. 2001
  4. ncbi Controlled release of water-soluble polymeric complexes of sorbic acid with antifungal activities
    E Charvalos
    School of Health and Caring Professions, Technological Educational Institution of Athens, Greece
    Appl Microbiol Biotechnol 57:770-5. 2001
  5. ncbi Penetration and distribution of alpha-tocopherol, alpha- or gamma-tocotrienols applied individually onto murine skin
    M G Traber
    Department of Molecular and Cell Biology, University of California, Berkeley 94720 3200, USA
    Lipids 33:87-91. 1998
  6. doi Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases
    Guo Nan Yin
    Department of Pharmacology, Brain Science and Engineering Institute, CMRI, Kyungpook National University School of Medicine, Joong Gu, Daegu, South Korea
    Brain Res 1265:158-70. 2009
  7. doi Cloning and characterization of cell strains derived from human corneal stroma and sclera
    Yoshiko Kashiwagi
    Department of Ocular Cellar Engineering, Yamagata University, Yamagata, Japan
    Jpn J Ophthalmol 54:74-80. 2010
  8. pmc Complementation of the mpg1 mutant phenotype in Magnaporthe grisea reveals functional relationships between fungal hydrophobins
    M J Kershaw
    Department of Biological Sciences, University of Exeter, Washington Singer Laboratories, Perry Road, Exeter EX4 4QG, UK
    EMBO J 17:3838-49. 1998
  9. ncbi SC3 and SC4 hydrophobins have distinct roles in formation of aerial structures in dikaryons of Schizophyllum commune
    M A van Wetter
    Groningen Biomolecular Sciences and Biotechnology Institute, Laboratory of Molecular Plant Biology and Department of Microbiology, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    Mol Microbiol 36:201-10. 2000
  10. ncbi A flexible array format for large-scale, rapid blood group DNA typing
    Ghazala Hashmi
    BioArray Solutions Ltd, Warren, New Jersey, USA
    Transfusion 45:680-8. 2005

Research Grants

  1. Towards a vaccine against Fasciola hepatica using FhSAP2 as an antigen
    Ana M Espino; Fiscal Year: 2013
  2. Matricellular Proteins in Trabecular Meshwork Increase Intraocular Pressure
    Douglas J Rhee; Fiscal Year: 2013
  3. Yiming Liu; Fiscal Year: 2016
  4. WILLIAM CHRISTOPHER RISHER; Fiscal Year: 2014
  5. Walid M Al Ghoul; Fiscal Year: 2015
  6. Gregory Boutis; Fiscal Year: 2016
  7. KELLY ELAINE JOHANSON; Fiscal Year: 2014
  8. Weigang Qiu; Fiscal Year: 2016
  9. MEHNAAZ FATIMA ALI; Fiscal Year: 2015
  10. Cagla Eroglu; Fiscal Year: 2016

Detail Information

Publications156 found, 100 shown here

  1. ncbi [Molecular characterization of hepatitis E virus in three acute liver failure cases in children in Argentina]
    María Silvina Munné
    Laboratorio Nacional de Referencia para Hepatitis Virales, Instituto Nacional de Enfermedades Infecciosas, A N L I S C G Malbrán, Buenos Aires, Argentina
    Acta Gastroenterol Latinoam 36:125-30. 2006
    ..This data suggests a potential link between ALF and HEVin children in Argentina and indicates the need for the determination of HEV status in the differential diagnosis in ..
  2. ncbi Matrix glycoprotein SC1/ECM2 augments B lymphopoiesis
    K Oritani
    Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA
    Blood 90:3404-13. 1997
    ..It was recently discovered that matrix glycoprotein SC1/ECM2 is a component of that matrix and preliminary evidence suggested that it could contribute to the nurturing ..
  3. ncbi Expression of mRNA encoding extracellular matrix glycoproteins SPARC and SC1 is temporally and spatially regulated in the developing cochlea of the rat inner ear
    A J Mothe
    Department of Zoology, University of Toronto at Scarborough, M1C 1A4, Toronto, ON, Canada
    Hear Res 155:161-74. 2001
    SPARC is a multifunctional extracellular matrix (ECM) glycoprotein that shares partial sequence homology with SC1/hevin. These ECM molecules exhibit calcium-binding properties and modulate cellular interactions...
  4. ncbi Controlled release of water-soluble polymeric complexes of sorbic acid with antifungal activities
    E Charvalos
    School of Health and Caring Professions, Technological Educational Institution of Athens, Greece
    Appl Microbiol Biotechnol 57:770-5. 2001
    ..As shown by infrared absorption spectrum analysis, the complexes were formed by hydrogen bonding. The complexes (SC1, with mol wt=10 kDa, SC2 with mol wt=25 kDa, SC3 with mol wt=30 kDa, SC4 with mol wt=40 kDa, SC5 with mol wt=90 kDa,..
  5. ncbi Penetration and distribution of alpha-tocopherol, alpha- or gamma-tocotrienols applied individually onto murine skin
    M G Traber
    Department of Molecular and Cell Biology, University of California, Berkeley 94720 3200, USA
    Lipids 33:87-91. 1998
    ..removed, frozen on dry ice, and a biopsy taken and sectioned: stratum corneum (two uppermost, 5-micron sections--SC1 and SC2), epidermis (next two 10-micron sections--E1 and E2), papillary dermis (next 100 microns, PD), dermis (next ..
  6. doi Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases
    Guo Nan Yin
    Department of Pharmacology, Brain Science and Engineering Institute, CMRI, Kyungpook National University School of Medicine, Joong Gu, Daegu, South Korea
    Brain Res 1265:158-70. 2009
    ..This study suggests that NCAM-120, alpha-dystroglycan, and NPR are candidate biomarkers in CSF for neurodegenerative diseases, and that the changes in the CSF level of NPR may be specific for AD...
  7. doi Cloning and characterization of cell strains derived from human corneal stroma and sclera
    Yoshiko Kashiwagi
    Department of Ocular Cellar Engineering, Yamagata University, Yamagata, Japan
    Jpn J Ophthalmol 54:74-80. 2010
    ..To establish human corneal stroma- and sclera-derived cells as models for studying diseases of the anterior segment of the eye...
  8. pmc Complementation of the mpg1 mutant phenotype in Magnaporthe grisea reveals functional relationships between fungal hydrophobins
    M J Kershaw
    Department of Biological Sciences, University of Exeter, Washington Singer Laboratories, Perry Road, Exeter EX4 4QG, UK
    EMBO J 17:3838-49. 1998
    ..Each hydrophobin was introduced into an mpg1(-) mutant by transformation. Only one hydrophobin gene, SC1 from Schizophyllum commune, was able partially to complement mpg1(-) mutant phenotypes when regulated by its own ..
  9. ncbi SC3 and SC4 hydrophobins have distinct roles in formation of aerial structures in dikaryons of Schizophyllum commune
    M A van Wetter
    Groningen Biomolecular Sciences and Biotechnology Institute, Laboratory of Molecular Plant Biology and Department of Microbiology, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    Mol Microbiol 36:201-10. 2000
    ..Other dikaryon-specific hydrophobin genes, SC1 and SC6, apparently do not substitute for the SC4 gene...
  10. ncbi A flexible array format for large-scale, rapid blood group DNA typing
    Ghazala Hashmi
    BioArray Solutions Ltd, Warren, New Jersey, USA
    Transfusion 45:680-8. 2005
    ..The purpose of this study was to determine the feasibility of the use of large-scale DNA analysis in a microarray as a substitute for blood group typing...
  11. ncbi Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord
    Allison K Dillon
    Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Neurosci 25:10119-30. 2005
    ..Here we show that an antibody against BEN/ALCAM/SC1/DM-GRASP/MuSC selectively labels mouse SACMNs and can be used to trace the pathfinding of SACMN axons...
  12. ncbi Genetic polymorphisms in the cell growth regulated gene, SC1 telomeric of the HLA-C gene and lack of association of psoriasis vulgaris
    Y Teraoka
    Department of Genetic Information, Tokai University School of Medicine, Kanagawa, Japan
    Tissue Antigens 55:206-11. 2000
    ..This segment includes three known genes (POU5F1, SC1 and S) and four new expressed genes...
  13. doi N-methyl-D-aspartate mechanisms in depolarization of augmenting expiratory neurons during the expulsive phase of fictive cough in decerebrate cats
    Akira Haji
    Laboratory of Neuropharmacology, School of Pharmacy, Aichi Gakuin University, 1 100 Kusumoto, Chikusa, Nagoya 464 8650, Japan
    Neuropharmacology 54:1120-7. 2008
    ..which was characterized by an increased inspiratory discharge in the phrenic nerve (the stage 1 of fictive cough; SC1) and large spindle-shaped discharge in the iliohypogastric nerve (the stage 2 of fictive cough; SC2)...
  14. doi Evaluating the survival and environmental fate of the biocontrol agent Trichoderma atroviride SC1 in vineyards in northern Italy
    C M O Longa
    SafeCrop Centre, Fondazione Edmund Mach, San Michele all Adige, Trento, Italy
    J Appl Microbiol 106:1549-57. 2009
    To study the survival in the soil and the dispersion in the environment of Trichoderma atroviride SC1 after soil applications in a vineyard.
  15. ncbi The characterization, molecular cloning, and expression of a novel hematopoietic cell antigen from CD34+ human bone marrow cells
    N Uchida
    SyStemix Inc, Palo Alto, CA 94304, USA
    Blood 89:2706-16. 1997
    The adhesion molecule BEN/SC1/DM-GRASP (BEN) is a marker in the developing chicken nervous system that is also expressed on the surface of embryonic and adult hematopoietic cells such as immature thymocytes, myeloid progenitors, and ..
  16. ncbi CAP components and EEG synchronization in the first 3 sleep cycles
    M G Terzano
    Istituto di Neurologia, Universita degli Studi, Parma, Italy
    Clin Neurophysiol 111:283-90. 2000
    ..The present investigation aimed at assessing the involvement of the different components of CAP in the process of build-up, maintenance and demolition of deep non-REM (NREM) sleep...
  17. ncbi The HCR gene on 6p21 is unlikely to be a psoriasis susceptibility gene
    K P O'Brien
    Department of Dermatology, Karolinska Hospital, Stockholm, Sweden
    J Invest Dermatol 116:750-4. 2001
    ..rod homolog gene (HCR, previously Pg8) is located 110 kb from the HLA-C gene, positioned between the CDSN and SC1 genes, within a region thought to harbor a psoriasis gene (PSORS1)...
  18. ncbi Thermodynamics of the fragile X mental retardation protein RGG box interactions with G quartet forming RNA
    Kimberly J Zanotti
    Department of Chemistry and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282, USA
    Biochemistry 45:8319-30. 2006
    ..In this study we have performed a thermodynamic analysis of the interactions between the FMRP RGG box domain and Sc1, an RNA molecule which had been previously shown to be bound with high affinity by both the full-length FMRP and by ..
  19. pmc Association of biomarkers with pre-radiographically defined and radiographically defined knee osteoarthritis in a population-based study
    Jolanda Cibere
    University of British Columbia, and Arthritis Research Centre of Canada, Vancouver General Hospital, Vancouver, British Columbia, Canada
    Arthritis Rheum 60:1372-80. 2009
    ..To evaluate 10 biomarkers in magnetic resonance imaging (MRI)-determined, pre-radiographically defined osteoarthritis (pre-ROA) and radiographically defined OA (ROA) in a population-based cohort of subjects with symptomatic knee pain...
  20. pmc Interaction of recombinant myocilin with the matricellular protein SPARC: functional implications
    José Daniel Aroca-Aguilar
    Centro Regional de Investigaciones Biomédicas, Universidad de Castilla La Mancha, Albacete, Spain
    Invest Ophthalmol Vis Sci 52:179-89. 2011
    ..The authors previously reported that myocilin interacts with the C-terminal region of hevin, a secretory glycoprotein belonging to the SPARC family of matricellular proteins...
  21. doi 'Ca. Liberibacter asiaticus' carries an excision plasmid prophage and a chromosomally integrated prophage that becomes lytic in plant infections
    Shujian Zhang
    Plant Pathology Dept, University of Florida, Gainesville, FL 32611, USA
    Mol Plant Microbe Interact 24:458-68. 2011
    ..UF506, originally derived from citrus symptomatic for HLB, revealed two largely homologous, circular phage genomes, SC1 and SC2. SC2 encoded putative adhesin and peroxidase genes that had not previously been identified in 'Ca. L...
  22. ncbi MuSC, a novel member of the immunoglobulin superfamily, is expressed in neurons of a subset of cranial sensory ganglia in the mouse embryo
    Y Sekine-Aizawa
    Mitsubishi Kasei Institute of Life Sciences, Machida, Tokyo, Japan
    Eur J Neurosci 10:2810-24. 1998
    ..5% identity) to chicken SC1 protein...
  23. ncbi Correlation between clinical scoring of secondary caries at crown margins and histologically assessed extent of the lesions
    A Zoellner
    Department of Prosthodontics, School of Dental Medicine, University of Witten Herdecke, Alfred Herrhausen Strasse 50, 58448 Witten, Germany
    Int J Prosthodont 13:453-9. 2000
    ..The aim of this study was to propose a new clinical diagnostic rating index for secondary caries lesions at crown margins and to correlate this index with histologic evaluations...
  24. doi Differential expression patterns of OCC1-related, extracellular matrix proteins in the lateral geniculate nucleus of macaque monkeys
    Toru Takahata
    Division of Brain Biology, National Institute for Basic Biology, 38 Nishigonaka, Myodaiji, Okazaki, Aichi 444 8585, Japan
    J Chem Neuroanat 40:112-22. 2010
    ..We have found that expression of OCC1, testican-1, testican-2, testican-3, SPARC and SC1 mRNAs, which encode members of the OCC1-related family of ECM proteins, exhibits distinct activity-dependent ..
  25. ncbi Effects of a centipede venom fraction on insect nervous system, a native Xenopus oocyte receptor and on an expressed Drosophila muscarinic receptor
    M Stankiewicz
    Laboratory of Biophysics, Institute of General and Molecular Biology, N Copernicus University, Torun, Poland
    Toxicon 37:1431-45. 1999
    ..Application of a Scolopendra sp. venom fraction (SC1) on the cockroach giant axon induced an increase in the leak current correlated with a decrease in the membrane ..
  26. ncbi Differential gene expression profile of human tonsil high endothelial cells: implications for lymphocyte trafficking
    Diana Palmeri
    Department of Anatomy and Program of Immunology, University of California, San Francisco, USA
    J Leukoc Biol 75:910-27. 2004
    ..The two most abundant transcripts encoded alpha2-macroglobulin and hevin. The next-abundant transcripts encoded several other protease inhibitors, making this protein class the most ..
  27. doi Nitrogen dynamics of a mountain forest on dolomitic limestone--a scenario-based risk assessment
    R Jandl
    Federal Research and Training Centre for Forests, Natural Hazards and Landscape BFW Vienna, Vienna, Austria
    Environ Pollut 155:512-6. 2008
    ..The investigated scenarios were current climate, current N deposition (SC1) and future climate (+2.5 degrees C and +10% annual precipitation) with three levels of N deposition (SC2, 3, 4)...
  28. ncbi The thn mutation of Schizophyllum commune, which suppresses formation of aerial hyphae, affects expression of the Sc3 hydrophobin gene
    J G Wessels
    Department of Plant Biology, Biological Center, University of Groningen, Haren, The Netherlands
    J Gen Microbiol 137:2439-45. 1991
    ..Sc3 gene, and in the dikaryon it also prevents the accumulation of fruiting-specific mRNAs, including mRNAs of the Sc1 and Sc4 genes, which are homologous to the Sc3 gene...
  29. ncbi Cell adhesion molecule SC1/DMGRASP is expressed on growing axons of retina ganglion cells and is involved in mediating their extension on axons
    G E Pollerberg
    Max Planck Institute for Developmental Biology, Department of Biochemistry, Tubingen, Germany
    Dev Biol 165:670-87. 1994
    ..series of properties, including the N-terminal amino acid sequence, with a cell adhesion molecule termed DM-GRASP, SC1, BEN, and JC7. It can therefore be considered identical with this molecule and is referred to as SC1/DMGRASP...
  30. ncbi Distribution and characteristics of a 90 kDa protein, KG-CAM, in the rat CNS
    J D Peduzzi
    Department of Physiological Optics, University of Alabama at Birmingham 35294
    Brain Res 640:296-307. 1994
    ..a sequence homology with a group of chick cell adhesion molecules from the immunoglobulin superfamily: DM-GRASP; SC1; and BEN...
  31. pmc Cloning and characterization of a gene cluster for cyclododecanone oxidation in Rhodococcus ruber SC1
    K Kostichka
    Biological and Chemical Sciences and Engineering, Central Research and Development, E I DuPont de Nemours, Inc, Wilmington, Delaware 19880 0328, USA
    J Bacteriol 183:6478-86. 2001
    ..Rhodococcus ruber strain SC1 was isolated from an industrial wastewater bioreactor that was able to utilize cyclododecanone as the sole carbon ..
  32. ncbi Gene expression profiling in silico: relative expression of candidate angiogenesis associated genes in renal cell carcinomas
    Mary E Gerritsen
    Department of Cardiovascular Research, Genentech, South San Francisco, CA, USA
    Exp Nephrol 10:114-9. 2002
    ..One gene, hevin, appears to be selectively upregulated in RCC in contrast to downregulation of this gene in lung and colon tumors...
  33. ncbi Gene expression during acute allograft rejection: novel statistical analysis of microarray data
    Mark Stegall
    Department of Surgery, Division of Transplantation, Mayo Foundation and Clinic, 200 First St SW, Rochester, MN 55905, USA
    Am J Transplant 2:913-25. 2002
    ..Down-regulated transcripts included many novel molecules such as SC1 and decorin. LAR analysis provides a useful approach to analyze microarray data...
  34. ncbi Expression profiling identifies 147 genes contributing to a unique primate neointimal smooth muscle cell phenotype
    Randolph L Geary
    Department of Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Arterioscler Thromb Vasc Biol 22:2010-6. 2002
    ..This study represents the first in an effort to systematically characterize different intimas by using expression array analysis...
  35. ncbi Mapping of porcine ESTs obtained from the anterior pituitary
    G R Bertani
    Department of Animal Science, University of Nebraska, Lincoln, NE, USA
    Anim Genet 34:132-4. 2003
    ....
  36. pmc The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E
    Alexandra Chittka
    Institute for Clinical Neurobiology, University of Wurzburg, Wurzburg, Germany
    J Cell Biol 164:985-96. 2004
    Schwann cell factor 1 (SC1), a p75 neurotrophin receptor-interacting protein, is a member of the positive regulatory/suppressor of variegation, enhancer of zeste, trithorax (PR/SET) domain-containing zinc finger protein family, and it ..
  37. pmc Genetic basis for the evolution of vertebrate mineralized tissue
    Kazuhiko Kawasaki
    Department of Anthropology, 409 Carpenter Building, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 101:11356-61. 2004
    ..We also suggest that mammalian enamel is distinct from fish enameloid. Their similar nature as a hard structural overlay on exoskeleton and teeth is because of convergent evolution...
  38. pmc Matricellular homologs in the foreign body response: hevin suppresses inflammation, but hevin and SPARC together diminish angiogenesis
    Thomas H Barker
    Hope Heart Program, Benaroya Research Institute at Virginia Mason, 1201 Ninth Ave, Seattle, WA 98101, USA
    Am J Pathol 166:923-33. 2005
    ..In this report we delineate functions of hevin and SPARC, two homologs of the SPARC family of matricellular proteins, in the foreign body response...
  39. ncbi Heat processing in infant formulas induces changes in copper tissue levels in suckling and weanling rats
    Beatriz Sarria
    Departamento de Metabolismo y Nutricion, Instituto del Frio CSIC, Madrid, Spain
    Ann Nutr Metab 50:25-30. 2006
    ..To assess the effects of dehydration, conventional in-bottle sterilization, and ultrahigh-temperature (UHT) sterilization, involved in the production of infant formulas, on the copper bioavailability in rats at two stages...
  40. ncbi Expression and adhesive activity of SC1, an Ig superfamily cell adhesion molecule, in sporadic nephroblastomas of chicken
    Yasuhiro Tsukamoto
    Laboratory of Veterinary Anatomy, Graduate School of Biology and Environmental Sciences, Osaka Prefecture University, Japan
    Oncol Rep 15:137-41. 2006
    b>SC1, an immunoglobulin superfamily cell adhesion molecule, is transiently expressed during avian embryogenesis by a variety of cell types...
  41. ncbi Fine mapping of the recessive genic male-sterile gene (Bnms1) in Brassica napus L
    Bin Yi
    National Key Laboratory of Crop Genetic Improvement, National Sub center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China
    Theor Appl Genet 113:643-50. 2006
    ..On the fine map, Bnms1 gene was flanked by two SCAR markers, SC1 and SC7, with genetic distance of 0.1 cM and 0.3 cM, respectively...
  42. ncbi Arbuscular mycorrhizas and ectomycorrhizas of Uapaca bojeri L. (Euphorbiaceae): sporophore diversity, patterns of root colonization, and effects on seedling growth and soil microbial catabolic diversity
    Naina Ramanankierana
    Laboratoire de Microbiologie de l Environnement, Centre National de Recherches sur l Environnement, P O Box 1739, Antananarivo, Madagascar
    Mycorrhiza 17:195-208. 2007
    ..The use of selected mycorrhizal fungi such the Scleroderma Sc1 isolate in nursery conditions could be of great interest as (1) this fungal strain is very competitive against ..
  43. doi Genetic mapping of Bt-toxin binding proteins in a Cry1A-toxin resistant strain of diamondback moth Plutella xylostella
    Simon W Baxter
    CESAR, Department of Genetics, University of Melbourne, Parkville, VIC 3010, Australia
    Insect Biochem Mol Biol 38:125-35. 2008
    ..the Cry1Ac resistance locus, eliminating them as candidate resistance genes in the parental resistant strain SC1. Although this finding excludes cis-acting mutations in these genes as causing resistance in this strain, one or ..
  44. ncbi Nitric oxide synthases as shared targets for reproductive hormones. Comment to: Estrogen's actions transcend a sole reproductory function in cell signalling Kirk Mantione Med Sci Monit 2008; 14(2): SC1-3
    Maria Caterina Baccari
    Med Sci Monit 14:LE5-6. 2008
  45. doi Expression of paralogs of cytochrome P 450 21a1 pseudogene (Cyp21a1-ps) and endogenous retrovirus SC1 (SC1) in the rat ovary during the ovulatory process
    Lawrence L Espey
    Department of Biology, One Trinity Place, Trinity University, San Antonio, Texas 78212, USA
    J Endocrinol 198:231-41. 2008
    ..The remaining five clones were paralogs of the endogenous retrovirus SC1 that has heavily infested the rat genome...
  46. doi Ecophysiological requirements and survival of a Trichoderma atroviride isolate with biocontrol potential
    Claudia Maria Oliveira Longa
    SafeCrop Centre, IASMA, San Michele all Adige, Trento, Italy
    J Basic Microbiol 48:269-77. 2008
    Trichoderma atroviride SC1, isolated from decayed hazelnut wood in northern Italy in 2000, is a promising fungal agent for biological control of soil-borne plant pathogens...
  47. doi Extracellular matrix protein SC1/hevin in the hippocampus following pilocarpine-induced status epilepticus
    Starlee Lively
    Center for the Neurobiology of Stress, University of Toronto at Scarborough, Toronto, Ontario, Canada
    J Neurochem 107:1335-46. 2008
    ..In this study, distribution of the anti-adhesive extracellular matrix protein SC1 was examined in the rat hippocampus following SE...
  48. doi Three-dimensional analysis of intracycle velocity fluctuations in frontcrawl swimming
    S G Psycharakis
    School of Life Sciences, Napier University, Edinburgh, UK
    Scand J Med Sci Sports 20:128-35. 2010
    ..Vmax and Vmin were positively correlated to performance and were significantly higher in SC1 than in the other SCs...
  49. pmc Easy identification of antibodies to high-prevalence Scianna antigens and detection of admixed alloantibodies using soluble recombinant Scianna protein
    Axel Seltsam
    German Red Cross Blood Donor Service NSTOB, Institute Springe, Springe, Germany
    Transfusion 49:2090-6. 2009
    Identification of antibodies against high-prevalence Scianna (Sc; ERMAP) antigens, like Sc1 and Sc5, is difficult and may incur delays in blood procurement and costs...
  50. doi Discovery of functional motifs in h-regions of trypanosome signal sequences
    Josh Duffy
    Department of Cellular Biology, 724 Biological Sciences Building, University of Georgia, Athens, GA 30602, USA
    Biochem J 426:135-45. 2010
    ..Example of h-motifs are human Hs3 {L-x(2)-[AGILPV]-L-x(0,2)-L}, S. cerevisiae Sc1 [L-x(0,2)-S-x(0,3)-A], T. brucei Tb2 {L-x(1,2)-L-[AILV]} and E. coli Ec1 [A-x(0,2)-L-x(0,3)-A]...
  51. pmc Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA
    Ernest Blackwell
    Department of Cell and Developmental Biology, College of Medicine, University of Illinois, Urbana Champaign, IL 61801, USA
    Hum Mol Genet 19:1314-23. 2010
    ..The model G-quadruplex RNA sc1 required arginines 533 and 538 for normal association with FMRP, whereas AATYK mRNA did not...
  52. pmc Expression, functional, and structural analysis of proteins critical for otoconia development
    Yinfang Xu
    Vestibular Neurogenetics Laboratory, Boys Town National Research Hospital, Omaha, Nebraska 68131, USA
    Dev Dyn 239:2659-73. 2010
    ..list of plausible candidates, and have found a drastic increase in the deposition of Sparc-like 1 (aka Sc1 or hevin) in Oc90 null versus wt otoconia...
  53. doi Expression of SC1, a cell adhesion molecule, promotes the metastatic activities of the Gallus gallus lymphoblastoid cell line MDCC-MSB1 derived from Marek's disease
    Ekowati Handharyani
    Department of Veterinary Pathology, Faculty of Veterinary Medicine, Bogor Agriculture University, Bogor, Indonesia
    Avian Pathol 40:111-5. 2011
    b>SC1 is an immunoglobulin superfamily cell adhesion molecule purified from the Gallus gallus spinal cord. SC1 is present in embryonic tissues and plays a role in chick development through its cell adhesive property...
  54. pmc SPARCL1, Shp2, MSH2, E-cadherin, p53, ADCY-2 and MAPK are prognosis-related in colorectal cancer
    Shu jing Yu
    Department of Radiation Oncology, The Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 17:2028-36. 2011
    ..To investigate the expression of markers that are correlated with the prognosis of colorectal cancer (CRC) patients...
  55. doi SC1/hevin and reactive gliosis after transient ischemic stroke in young and aged rats
    Starlee Lively
    Toronto Western Research Institute, University Health Network, Toronto, Canada
    J Neuropathol Exp Neurol 70:913-29. 2011
    b>SC1 is a member of the SPARC family of glycoproteins that regulate cell-matrix interactions in the developing brain. SC1 is expressed in astrocytes, but nothing is known about the expression in the aged or after stroke...
  56. doi SPARC-like 1 (SC1) is a diversely expressed and developmentally regulated matricellular protein that does not compensate for the absence of SPARC in the CNS
    Samantha Lloyd-Burton
    Department of Zoology, Life Sciences Institute and Brain Research Centre, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada
    J Comp Neurol 520:2575-90. 2012
    SPARC-like 1 (SC1) is a member of the SPARC family of matricellular proteins that has been implicated in the regulation of processes such as cell migration, proliferation, and differentiation...
  57. doi Identification of yeast and acetic acid bacteria isolated from the fermentation and acetification of persimmon (Diospyros kaki)
    C Hidalgo
    Biotecnologia Enològica, Dept Bioquímica i Biotecnologia, Facultat d Enologia, Universitat Rovira i Virgili, C Marcel li Domingo s n, 43007 Tarragona, Spain
    Food Microbiol 30:98-104. 2012
    ..cerevisiae became dominant toward the end of these processes. During spontaneous fermentation, S. cerevisiae Sc1 was the predominant strain isolated throughout, while the commercial strain of S...
  58. pmc Distinct roles of neuroligin-1 and SynCAM1 in synapse formation and function in primary hippocampal neuronal cultures
    S D Burton
    Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuroscience 215:1-16. 2012
    ..SynCAM1 (SC1) is hypothesized to function in this capacity, though several uncertainties remain regarding SC1 function...
  59. doi Influence of in ovo prebiotic and synbiotic administration on meat quality of broiler chickens
    G Maiorano
    Department of Agricultural, Environmental and Food Sciences, University of Molise, Campobasso, Italy
    Poult Sci 91:2963-9. 2012
    ..lactis SL1 and Lactococcus lactis ssp. cremoris IBB SC1, respectively; T4 with commercially available synbiotic Duolac, containing 500 cfu of both Lactobacillus ..
  60. pmc Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins
    Ayan Chatterjee
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Exp Eye Res 115:106-12. 2013
    ..strains with single gene mutations (KO) of thrombospondin-1 (TSP-1), thrombospondin-2 (TSP-2), osteopontin (OPN), hevin, and secreted protein acidic rich in cysteine (SPARC) were imaged at six weeks using optical coherence tomography (..
  61. doi Acoustic study of pharyngeal swallowing as a function of the volume and consistency of the bolus
    Karim Hammoudi
    University Francois Rabelais, Tours, France
    Dysphagia 29:468-74. 2014
    ..For each recorded sound, the total duration of the sound and the duration of each sound component (SC) (SC1, SC2, and SC3) and interval (IT1 and IT2) between the SCs were measured...
  62. doi Prophage-Encoded Peroxidase in 'Candidatus Liberibacter asiaticus' Is a Secreted Effector That Suppresses Plant Defenses
    Mukesh Jain
    Department of Plant Pathology, University of Florida, Gainesville, FL 32611 0680, U S A
    Mol Plant Microbe Interact 28:1330-7. 2015
    ..Most pathogenic 'Ca. L. asiaticus' strains carry two nearly identical prophages similar to SC1 and SC2 in strain UF506...
  63. pmc Color Pattern on the Forewing of Micropterix (Lepidoptera: Micropterigidae): Insights into the Evolution of Wing Pattern and Wing Venation in Moths
    Sandra R Schachat
    Mississippi Entomological Museum, Mississippi State, Mississippi, United States of America Department of Paleobiology, Smithsonian Institution, Washington, District of Columbia, United States of America
    PLoS ONE 10:e0139972. 2015
    ..In addition, the location of wing pattern elements suggests that the wing vein commonly termed Sc1 may in fact be a different vein, which Comstock identified in Trichoptera and referred to as "a."
  64. doi Clusters of Structurally Similar MHC I HLA-A2 Molecules, Found with a New Method, Suggest Mechanisms of T-Cell Receptor Avidity
    Alexander A Rashin
    BioChemComp Inc, 543 Sagamore Avenue, Teaneck, New Jersey 07666, United States
    Biochemistry 55:167-85. 2016
    ..Strong hydrogen bonds between (α1 + α2) and α3 differ between SC1 and SC2 but are nearly invariant within each SC...
  65. doi Morpho-chemical characterization and surface properties of carcinogenic zeolite fibers
    Michele Mattioli
    Department of Earth, Life and Environment Sciences, University of Urbino, 61029 Urbino, Italy Electronic address
    J Hazard Mater 306:140-8. 2016
    ..performed on two erionites (GF1, MD8) and one offretite (BV12) fibrous samples and, for comparison, one scolecite (SC1) sample...
  66. pmc Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury
    Jennifer L Furman
    Department of Pharmacology and Nutritional Sciences
    J Neurosci 36:1502-15. 2016
    ..effects, VIVIT treatment elicited a marked increase in the expression of the prosynaptogenic factor SPARCL1 (hevin), especially in hippocampal tissue ipsilateral to the CCI injury...
  67. pmc Inhibition of JAK-STAT ERK/MAPK and Glycogen Synthase Kinase-3 Induces a Change in Gene Expression Profile of Bovine Induced Pluripotent Stem Cells
    Luis F Malaver-Ortega
    CSIRO Health and Biosecurity, East Geelong, VIC 3219, Australia Monash Institute for Medical Research, Monash University, Clayton, VIC 3168, Australia
    Stem Cells Int 2016:5127984. 2016
    ..It was found that the use of 6-bromoindirubin-3-oxime and Sc1 inhibitors alone or in combination with 5-AzaC induced significantly higher levels of expression of endogenous REX1,..
  68. pmc Expression of SPARC like protein 1 (SPARCL1), extracellular matrix-associated protein is down regulated in gastric adenocarcinoma
    Aniruddha Jakharia
    1 Imgenex India Pvt Ltd, Bhubaneswar, India 2 Regional Medical Research Centre for NE Region Indian Council of Medical Research, Assam, India
    J Gastrointest Oncol 7:278-83. 2016
    SPARC-like protein 1 (SPARCL1/Hevin), a member of the SPARC family is defined by the presence of a highly acidic domain-I, a follistatin-like domain, and an extracellular calcium (EC) binding domain...
  69. doi Soil and river contamination patterns of chlordecone in a tropical volcanic catchment in the French West Indies (Guadeloupe)
    A Crabit
    Montpellier SupAgro, UMR LISAH, 2 Place Pierre Viala, 34060 Montpellier, France Electronic address
    Environ Pollut 212:615-26. 2016
    ..Three sub-catchments (SC1, SC2 and SC3) were studied during the hydrological year 2009-2010: a pedological survey combined with a spatialized ..
  70. doi Diversity and Toxicity of Bacillus thuringiensis from Shifting Cultivation (Jhum) Habitat
    Ralte Zothansanga
    Department of Biotechnology, Mizoram University
    Biocontrol Sci 21:99-111. 2016
    ..Based on the toxicity test, SC1 and HP7 isolates containing cry 4 and cry 9 genes showed higher activity...
  71. doi Andreev and Majorana bound states in single and double quantum dot structures
    Joelson F Silva
    Instituto de Fisica, Universidade Federal de Uberlandia, Uberlandia, Minas Gerais 38400 902, Brazil
    J Phys Condens Matter 28:435702. 2016
    ..bound states in a system composed of two quantum dots, one of which is coupled to a conventional superconductor, SC1, and the other connects to a topological superconductor, SC2...
  72. doi SPARCL1 a novel player in cancer biology
    Filippo Gagliardi
    Department of Neurosurgery and Gamma Knife Radiosurgery, San Raffaele Scientific Institute, Vita Salute University, Milan, Italy Electronic address
    Crit Rev Oncol Hematol 109:63-68. 2017
    ..Aim of this review is to critically revise current knowledges about the role, played by SPARCL1, in physiological and pathological contexts and highlight its role as a key-gene in the regulation of tumor biology...
  73. ncbi The exon structure of the mouse Sc1 gene is very similar to the mouse Sparc gene
    P J McKinnon
    Genome Res 6:1077-83. 1996
    b>Sc1 and Sparc are two extracellular proteins sharing similarity in their carboxyl terminus, with 63% identity over a 232-amino-acid region. We have cloned and mapped the genomic locus of mouse Sc1...
  74. ncbi An expression signature classifies chemotherapy-resistant pediatric osteosarcoma
    Michelle B Mintz
    Neurogenomics Division and Genetic Basis of Human Disease Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, USA
    Cancer Res 65:1748-54. 2005
    ..We propose that osteosarcoma tumor-driven changes in the bone microenvironment contribute to the chemotherapy-resistant phenotype and offer testable hypotheses to potentially enhance therapeutic response...
  75. ncbi Duplication of the S-locus F-box gene is associated with breakdown of pollen function in an S-haplotype identified in a natural population of self-incompatible Petunia axillaris
    Tatsuya Tsukamoto
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Plant Mol Biol 57:141-53. 2005
    ..axillaris, and found that all the self-compatible plants studied carried either SC1- or SC2-haplotype...
  76. pmc SPARCL1 suppresses metastasis in prostate cancer
    Yuzhu Xiang
    Department of Medicine, Vanderbilt University, Nashville, TN 37232 0275, USA Minimally Invasive Urology Center, Provincial Hospital affiliated to Shandong University, Jinan 250021, China Electronic address
    Mol Oncol 7:1019-30. 2013
    ..Metastasis, the main cause of death from cancer, remains poorly understood at the molecular level...
  77. doi Oct4 and the small molecule inhibitor, SC1, regulates Tet2 expression in mouse embryonic stem cells
    Yongyan Wu
    College of Veterinary Medicine, Northwest A and F University, Key Laboratory of Animal Biotechnology, Ministry of Agriculture, 3 TaiCheng Road, Yangling 712100, China
    Mol Biol Rep 40:2897-906. 2013
    ..Furthermore, we explored the role of the small molecule inhibitor, SC1 (pluripotin) on Tet gene expression...
  78. doi Bioinformatic analysis of chemokine (C-C motif) ligand 21 and SPARC-like protein 1 revealing their associations with drug resistance in ovarian cancer
    Fuqiang Yin
    Department of Gynecologic Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P R China
    Int J Oncol 42:1305-16. 2013
    Chemokine (C-C motif) ligand 21 (CCL21) and SPARC-like protein 1 (SPARCL1/MAST9/hevin/SC-1) are associated with various biological behavior in the development of cancers...
  79. doi Genetic basis of woven nest size in subsocial spider mites
    Kotaro Mori
    Laboratory of Animal Ecology, Graduate School of Agriculture, Hokkaido University, Sapporo, Japan
    Exp Appl Acarol 60:463-9. 2013
    ..It is known that the length of the dorsal setae (sc1, 2nd propodosomal setae) correlates with the nest size...
  80. pmc Differential regulation of SC1/PRDM4 and PRMT5 mediated protein arginine methylation by the nerve growth factor and the epidermal growth factor in PC12 cells
    Alexandra Chittka
    Wolfson Institute for Biomedical Research, University College London, London, WC1E 6BT, United Kingdom
    Neurosci Lett 550:87-92. 2013
    ..We recently showed that a member of the PRDM family of transcriptional regulators, PRDM4/SC1, recruits a type II protein arginine methyltransferase, PRMT5, to maintain the "stem-like" cellular state of the ..
  81. pmc BEN/SC1/DM-GRASP, a homophilic adhesion molecule, is required for in vitro myeloid colony formation by avian hemopoietic progenitors
    C Corbel
    Insitut d Embryologic Cellulaire et Moléculaire du Centre National de Recherche Scientifique, Nogent sur Marne, France
    Proc Natl Acad Sci U S A 93:2844-9. 1996
    BEN/SC1/DM-GRASP is a membrane glycoprotein of the immunoglobulin superfamily isolated in the chick by several groups, including ours...
  82. ncbi Expression of the cell adhesion proteins BEN/SC1/DM-GRASP and TAG-1 defines early steps of axonogenesis in the human spinal cord
    D Karagogeos
    Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology, University of Crete School of Medicine, Greece
    J Comp Neurol 379:415-27. 1997
    We have studied the expression pattern of two cell adhesion proteins of the immunoglobin (Ig) superfamily, BEN/SC1/DM-GRASP (BEN) and the transient axonal glycoprotein TAG-1, during the development of the human nervous system...
  83. ncbi SPARC and tumor growth: where the seed meets the soil?
    Paul E Framson
    Department of Vascular Biology, The Hope Heart Institute, 1124 Columbia Street, Seattle, Washington 98104, USA
    J Cell Biochem 92:679-90. 2004
    ..SPARC, a prototypic matricellular protein, and its homolog hevin, have deadhesive effects on cultured cells and have been characterized as antiproliferative factors in some ..
  84. doi Characteristics of isolated lactic acid bacteria and their effectiveness to improve stylo (Stylosanthes guianensis Sw.) silage quality at various temperatures
    Qinhua Liu
    Department of Grassland Science, South China Agricultural University, Guangzhou, China
    Anim Sci J 83:128-35. 2012
    Two lactic acid bacteria (LAB) strains, Pediococcus pentosaceus SC1 and Lactobacillus paraplantarum SC2 isolated from king grass silage, were characterized and their effectiveness to improve the silage fermentation quality of stylo (..
  85. doi Soil properties predict plant community development of mitigation wetlands created in the Virginia Piedmont, USA
    Suzanne M Dee
    Department of Environmental Science and Policy, George Mason University, 4400 University Drive, Fairfax, VA 22030, USA
    Environ Manage 49:1022-36. 2012
    ..e., SC1 > SC2 > SC3 > SC4, trended more to less developed)...
  86. pmc Modulation of intestinal inflammation by yeasts and cell wall extracts: strain dependence and unexpected anti-inflammatory role of glucan fractions
    Samir Jawhara
    Universite Lille Nord de France, Lille, France
    PLoS ONE 7:e40648. 2012
    ..5% dextran-sulphate-sodium (DSS) for 2 weeks followed by a 3-day restitution period. S. cerevisiae strains (Sb, Sc1 to Sc4), as well as mannoprotein (MP) and β-glucan crude fractions prepared from Sc2 and highly purified β-..
  87. doi Secreted protein acidic and rich in cysteines-like 1 suppresses aggressiveness and predicts better survival in colorectal cancers
    Hanguang Hu
    School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
    Clin Cancer Res 18:5438-48. 2012
    ..The hypothesis that SPARCL1 reduces cancer invasiveness and predicts better survival in colorectal cancers (CRC) was investigated...
  88. pmc BEN, a surface glycoprotein of the immunoglobulin superfamily, is expressed in a variety of developing systems
    O Pourquie
    Institut d Embryologie Cellulaire et Moleculaire, Nogent sur Marne, France
    Proc Natl Acad Sci U S A 89:5261-5. 1992
    ..R., Von Kannen, S., Guy, L., Raper, J. A., Kamholz, J. & Chang, S. (1991) Neuron 7, 209-220] and SC1 [Tanaka, H., Matsui, T., Agata, A., Tomura, M., Kubota, I., Mcfarland, K. C., Kohr, B., Lee, A., Phillips, H. S...
  89. ncbi Molecular cloning of SC1: a putative brain extracellular matrix glycoprotein showing partial similarity to osteonectin/BM40/SPARC
    I G Johnston
    Department of Zoology, University of Toronto, Ontario, Canada
    Neuron 4:165-76. 1990
    We describe the cloning of SC1, a novel cDNA that was selected from a rat brain expression library using a mixed polyclonal antibody directed against synaptic junction glycoproteins. SC1 detects a 3...
  90. ncbi A new growth-regulated complementary DNA with the sequence of a putative trans-activating factor
    D H Ku
    Department of Pathology, Temple University Medical School, Philadelphia, Pennsylvania 19104
    Cell Growth Differ 2:179-86. 1991
    ..The cognate RNA of this clone, called SC1, is growth regulated in human, mouse, and hamster cell lines...
  91. ncbi Mitomycin C induces genomic rearrangements involving transposable elements in Drosophila melanogaster
    P G Georgiev
    Vavilov Institute of General Genetics, USSR Academy of Sciences, Moscow
    Mol Gen Genet 220:229-33. 1990
    Mitomycin C was injected into the abdomen of male flies of the y2 sc1 waG strain of Drosophila melanogaster...
  92. ncbi The C-terminal portion of BM-40 (SPARC/osteonectin) is an autonomously folding and crystallisable domain that binds calcium and collagen IV
    P Maurer
    Abt Biophysikalische Chemie, Biozentrum University, Basel, Switzerland
    J Mol Biol 253:347-57. 1995
    ..BM-40 and several other related proteins (QR1, SC1/hevin, testican and tsc-36/FRP) are members of a novel modular protein family that share the FS domain followed by an EC ..
  93. ncbi Survival of newly postmitotic motoneurons is transiently independent of exogenous trophic support
    C Mettling
    INSERM U 382, Biochimie CNRS INSERM, Montpellier, France
    J Neurosci 15:3128-37. 1995
    ..Density gradient centrifugation followed by immunopanning using SC1 antibody allowed us to purify two size classes of motoneuron. Large motoneurons retained by 6...
  94. pmc The Lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver
    S F Parsons
    International Blood Group Reference Laboratory, Bristol, United Kingdom
    Proc Natl Acad Sci U S A 92:5496-500. 1995
    ..The overall structure is similar to that of the human tumor marker MUC 18 and the chicken neural adhesion molecule SC1. The extracellular domains and cytoplasmic domain contain consensus motifs for the binding of integrin and Src ..
  95. ncbi Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons
    B Lutz
    Department of Biochemistry, Baylor College of Medicine, Houston, TX 77030
    Development 120:25-36. 1994
    ..induced cCOUP-TF II gene expression in the dorsal spinal cord in a region coextensive with ectopic domains of SC1 and Islet-1, two previously identified motor neuron markers...
  96. ncbi cDNA subtraction library construction using a magnet-assisted subtraction technique (MAST)
    P Schraml
    Zentrum fur Lehre und Forschung, Basel, Switzerland
    Trends Genet 9:70-1. 1993
  97. ncbi Modulation of endothelial cell adhesion by hevin, an acidic protein associated with high endothelial venules
    J P Girard
    Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 271:4511-7. 1996
    ..Here, we show that this protein, designated hevin, is associated with basal, lateral, and apical surfaces of HEV cells, and unlike MECA-79 antigen, is not expressed ..
  98. pmc cemA homologue essential to CO2 transport in the cyanobacterium Synechocystis PCC6803
    A Katoh
    Graduate Division of Biochemical Regulation, Nagoya University, Japan
    Proc Natl Acad Sci U S A 93:4006-10. 1996
    ..very slowly in a low-sodium medium, which is unfavorable for HCO3(-) transport, and examined two of these mutants (SC1 and SC2) for their ability to take up CO2 and HCO3(-) in the light...
  99. pmc Identification of stromal cell products that interact with pre-B cells
    K Oritani
    Oklahoma Medical Research Foundation, Oklahoma City 73104, USA
    J Cell Biol 134:771-82. 1996
    ..This approach resulted in the cloning of biglycan, syndecan 4, collagen type I, clusterin, matrix glycoprotein sc1, osteonectin, and one unknown molecule (designated SIM)...
  100. ncbi Effects of a strain of Saccharomyces cerevisiae (Levucell SC1), a microbial additive for ruminants, on lactate metabolism in vitro
    F Chaucheyras
    Laboratoire de Microbiologie, Institut National de la Recherche Agronomique, Saint Genes Champanelle, France
    Can J Microbiol 42:927-33. 1996
    ..These results indicate that SC can be a very useful tool to reduce lactate accumulation in vitro during fermentation of soluble sugars...
  101. ncbi Cloning and expression of murine SC1, a gene product homologous to SPARC
    J A Soderling
    Department of Biological Structure, University of Washington, Seattle 98195 7420, USA
    J Histochem Cytochem 45:823-35. 1997
    A number of cDNAs (SC1, QR1, and hevin) have been shown to be similar to SPARC (secreted protein acidic and rich in cysteine), a matricellular protein that regulates cell adhesion, cell cycle, and matrix assembly and remodeling...

Research Grants24

  1. Towards a vaccine against Fasciola hepatica using FhSAP2 as an antigen
    Ana M Espino; Fiscal Year: 2013
    ..The main objective of PI with this SC1 application is to make a transition to a non-SCORE support mechanism and in doing so establish herself as an ..
  2. Matricellular Proteins in Trabecular Meshwork Increase Intraocular Pressure
    Douglas J Rhee; Fiscal Year: 2013
    ..The matricellular family includes SPARC, thrombospondins (TSP)-1 and -2, tenascins C and X, hevin, and osteopontin...
  3. Yiming Liu; Fiscal Year: 2016
    ..PUBLIC HEALTH RELEVANCE: The research proposed in this SC1 application aims to determine the effects of chemical stimuli on the biosynthesis and metabolism of (R)-NMSal (a ..
  4. WILLIAM CHRISTOPHER RISHER; Fiscal Year: 2014
    ..the contributions of three of these astrocyte-released signals, the matricellular proteins thrombospondin (TSP), hevin and SPARC, to the initial formation and maturation of excitatory synapses...
  5. Walid M Al Ghoul; Fiscal Year: 2015
    ..The publications due to this grant funding will also enhance the PI's scientific reputation and increase his ability to attract future mainstream grant funding such as SC1 and R01.
  6. Gregory Boutis; Fiscal Year: 2016
    ..The PI was previously funded for four years under an NIH SC1 proposal. This proposal is a renewal application requesting four additional years of funding...
  7. KELLY ELAINE JOHANSON; Fiscal Year: 2014
    ..studies on the role of the truncated FOXO1 DNA- binding domain in mediating DNA binding by Pax3-FOXO1 at the SC1 level...
  8. Weigang Qiu; Fiscal Year: 2016
    ..net as Open Source projects. The PI's specific aims for the proposed SC1 project are to (i) reveal genome variability associated with B...
  9. MEHNAAZ FATIMA ALI; Fiscal Year: 2015
    ..and will enable us to adapt the current research strategy to an electrochemical solid scaffold at the SC1 level with the long-term vision of developing real-time biosensors for multi-target detection...
  10. Cagla Eroglu; Fiscal Year: 2016
    ..In our preliminary studies, we identified another astrocyte-secreted synaptogenic protein, hevin. Addition of hevin to purified RGC cultures robustly stimulates excitatory synaptogenesis...
  11. SCORE Institutional Development Project at New Mexico State Univ.
    GLENN D KUEHN; Fiscal Year: 2011
    ..in a shared, core instrumentation facility which provides analytical services required by the investigators of SC1, SC2, SC3 (abbreviated SCn) SCORE grants...
  12. The role of stress and FoxP2 in adult vocal learning: tests using a parrot model
    Timothy F Wright; Fiscal Year: 2013
    ..This SC1 funding will also contribute to the professional development of the PI and enhance biomedical research at a ..
  13. Conformations of c-type cytochrome self-assembling complexes
    KRISTY LYNN MARDIS; Fiscal Year: 2010
    ..comparison of the calculated and experimental scattering data;(2) acquire sufficient data to allow submission of a SC1-type proposal...
  14. NUCLEAR PATHWAY FOR MESSENGER RNA DEGRADATION IN YEAST
    James Butler; Fiscal Year: 2002
    ..homologous to an autoantigen produced in patients suffering from Polymyositis Scleroderma Overlap Syndrome (PM-Sc1), as well as to the Werner's and Bloom's syndrome proteins implicated in premature aging...
  15. COMPLIANCE AND CONTROL IN CHILDHOOD DIABETES
    Suzanne Johnson; Fiscal Year: 1999
    ..adolescent patients will be randomized to IT, standard care (SC3), or standard care with frequent provider contact (SC1)...
  16. Syntheses of Highly Substituted Pryocatechols
    WAYNE FRANCIS SCHNATTER; Fiscal Year: 2010
    ..sufficient preliminary results to justify a more ambitious research program, which will be fundable through the SC1 mechanism, the ultimate goal being independence from SCORE funding and support through other programs (e.g...
  17. Hevin Regulation of Cell Migration
    MILLICENT SULLIVAN; Fiscal Year: 2005
    ..Matricellular proteins such as hevin play an important role in regulating cell/ECM communication and ECM structure by acting as adapters, and therefore ..
  18. Sc1 Proteins of S pyogenes: Biology and Function
    Slawomir Lukomski; Fiscal Year: 2005
    ..abstract_text> ..
  19. Effects of Mold Exposure on Brain and Behavior
    CHERYL HARDING; Fiscal Year: 2009
    ..to provide the mentoring and training I need to master the techniques needed for this research, complete the experiments, publish them in a timely fashion, and secure SC1 or equivalent funding to continue this line of research.
  20. ARTERY WALL CONTRACTION, WOUND HEALING, AND RESTENOSIS
    Randolph Geary; Fiscal Year: 2006
    ..Separate studies will explore the gene expression patterns induced during constrictive remodeling by applying RNA from arteries after injury, and from smooth muscle cells contracting collagen in vitro, to human gene arrays. ..
  21. IR-INDUCED APOPTOSIS IN THE DEVELOPING NERVOUS SYSTEM
    PETER MCKINNON; Fiscal Year: 2004
    ..Moreover, as neurodegenerative disease may engage similar apoptotic pathways, the findings from this proposal will be relevant for understanding neuronal death in neurodegenerative disease. ..
  22. ATM and DNA Damage in the Nervous System
    PETER MCKINNON; Fiscal Year: 2007
    ..abstract_text> ..
  23. VLA4 IN CTL MEDIATED ISLET ALLOGRAFT REJECTION
    Mark Stegall; Fiscal Year: 2001
    ..The approach may lead to novel forms of immune suppression that may benefit not only islet transplantation, but also other types of organ allografts. ..
  24. Regulation of Cell Function by Matricellular Hevin
    Thomas Wight; Fiscal Year: 2008
    ..Also known as SC-1, MAST 9, SPARC-like 1, and ECM2, hevin has been described as a tumor-suppressor gene that also features prominently in the ..