H3F3C

Summary

Gene Symbol: H3F3C
Description: H3 histone family member 3C
Alias: H3.5, histone H3.3C, H3 histone, family 3C, histone H3.5, histone variant H3.5
Species: human

Top Publications

  1. pmc A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants
    Anna Sadakierska-Chudy
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology Polish Academy of Sciences, Smetna Street 12, 31 343, Krakow, Poland
    Neurotox Res 27:84-97. 2015
  2. pmc Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis
    Takashi Urahama
    Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Institute for Medical oriented Structural Biology, Waseda University, 2 2 Wakamatsu cho, Shinjuku ku, Tokyo, 162 8480 Japan
    Epigenetics Chromatin 9:2. 2016
  3. ncbi The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting
    Marc A Holbert
    The Wistar Institute and Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104 0381, USA
    J Biol Chem 282:36603-13. 2007
  4. doi H3.5 is a novel hominid-specific histone H3 variant that is specifically expressed in the seminiferous tubules of human testes
    Raphael Schenk
    HELIOS Children s Hospital, HELIOS Klinikum Wuppertal, Research Laboratory, Witten Herdecke University, Germany
    Chromosoma 120:275-85. 2011

Scientific Experts

  • Anna Sadakierska-Chudy
  • Takashi Urahama
  • Raphael Schenk
  • Marc A Holbert
  • Yasuyuki Ohkawa
  • Wataru Kagawa
  • Kazumitsu Maehara
  • Koichi Sato
  • Norihiro Sugino
  • Yuko Sato
  • Akihito Harada
  • Hiroshi Kimura
  • Akihisa Osakabe
  • Koji Shiraishi
  • Hiroaki Tachiwana
  • Naoki Horikoshi
  • Hitoshi Kurumizaka
  • Jan Postberg
  • Andreas Jenke
  • Matthias Zilbauer
  • Stefan Wirth
  • Danielle Snowflack
  • Juliana Carten
  • Santosh Hodawadekar
  • Ronen Marmorstein
  • Timothy Sikorski

Detail Information

Publications4

  1. pmc A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants
    Anna Sadakierska-Chudy
    Laboratory of Drug Addiction Pharmacology, Institute of Pharmacology Polish Academy of Sciences, Smetna Street 12, 31 343, Krakow, Poland
    Neurotox Res 27:84-97. 2015
    ....
  2. pmc Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis
    Takashi Urahama
    Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Institute for Medical oriented Structural Biology, Waseda University, 2 2 Wakamatsu cho, Shinjuku ku, Tokyo, 162 8480 Japan
    Epigenetics Chromatin 9:2. 2016
    ..Human histone H3.5 is a non-allelic H3 variant evolutionally derived from H3.3. The H3.5 mRNA is highly expressed in human testis. However, the function of H3.5 has remained poorly understood...
  3. ncbi The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting
    Marc A Holbert
    The Wistar Institute and Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104 0381, USA
    J Biol Chem 282:36603-13. 2007
    ..Our results reveal, for the first time, that enzymatic and DNA-targeting activities can be contained within the same chromatin regulatory domain...
  4. doi H3.5 is a novel hominid-specific histone H3 variant that is specifically expressed in the seminiferous tubules of human testes
    Raphael Schenk
    HELIOS Children s Hospital, HELIOS Klinikum Wuppertal, Research Laboratory, Witten Herdecke University, Germany
    Chromosoma 120:275-85. 2011
    ..5 is assembled into chromatin and targeted by PTM. H3.5 preferentially colocalizes with euchromatin, and it is associated with actively transcribed genes and can replace an essential function of RNAi-depleted H3.3 in cell growth...