FBXO3

Summary

Gene Symbol: FBXO3
Description: F-box protein 3
Alias: FBA, FBX3, F-box only protein 3, F-box protein FBX3
Species: human

Top Publications

  1. ncbi cDNA cloning and expression analysis of new members of the mammalian F-box protein family
    G P Ilyin
    INSERM U522, Hopital Pontchaillou, Rennes, France
    Genomics 67:40-7. 2000
  2. pmc PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation
    Yutaka Shima
    Molecular Oncology Division, National Cancer Center Research Institute, Tokyo, Japan
    Mol Cell Biol 28:7126-38. 2008
  3. pmc Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia
    Tunahan Cakir
    Department of Chemical Engineering, Bogazici University, 34342, Bebek, Istanbul, Turkey
    Theor Biol Med Model 4:48. 2007
  4. ncbi [Immunophenotypic features of acute myeloid leukemia with AML-1/ETO fusion gene]
    Jian Jun Zhang
    Flow Cytomertry Laboratory, Department of Laboratory Medical Examination, Guangdong Provincial People s Hospital, Guangzhou 510080, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:378-81. 2007
  5. pmc Horizontal transfer of a eukaryotic plastid-targeted protein gene to cyanobacteria
    Matthew B Rogers
    Canadian Institute for Advanced Research, Department of Botany, University of British Columbia, Vancouver, BC, Canada
    BMC Biol 5:26. 2007
  6. ncbi Characterization of recombinant fructose-1,6-bisphosphate aldolase from Methylococcus capsulatus Bath
    O N Rozova
    Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    Biochemistry (Mosc) 75:892-8. 2010
  7. ncbi Fructose-1,6-bisphosphate aldolases in amitochondriate protists constitute a single protein subfamily with eubacterial relationships
    Lidya Sánchez
    The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Gene 295:51-9. 2002
  8. ncbi [Reliability of fetal pulse oximetry for the detection of fetal acidosis]
    B Seelbach-Göbel
    Klinik fur Frauenheilkunde und Geburtshilfe, St Hedwig Perinatalzentrum, Krankenhaus der Barmherzigen Bruder, Lehrstuhl der Universität Regensburg, Schwerpunkt Geburtshilfe, Regensburg
    Z Geburtshilfe Neonatol 209:43-50. 2005
  9. pmc Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans
    James S McCarthy
    University of Western Australia, Department of Medicine, Fremantle Hospital, Fremantle, Western Australia, Australia
    Infect Immun 70:851-8. 2002
  10. ncbi Archaeal fructose-1,6-bisphosphate aldolases constitute a new family of archaeal type class I aldolase
    B Siebers
    Department of Microbiology, Universitat Essen, 45117 Essen, Germany
    J Biol Chem 276:28710-8. 2001

Research Grants

  1. Hong Xin; Fiscal Year: 2014
  2. Targeting persistent M. tuberculosis through the inhibition of its aldolase
    Mary Jackson; Fiscal Year: 2010
  3. Assay Development of M. tuberculosis class II aldolase
    Mary Jackson; Fiscal Year: 2010
  4. Beibei Chen; Fiscal Year: 2016
  5. Nonablative AlloSCT in Refractory Autoimmune Disease
    Mitchell Cairo; Fiscal Year: 2003
  6. THE FnA D REGION OF TENASCIN C AND NEURONAL GROWTH
    Sally Meiners; Fiscal Year: 2005
  7. Novel Data Capture and Assessment Technology for Autism
    RONALD OBERLEITNER; Fiscal Year: 2006
  8. Automatic Generation of Genome-scale Flux Balance Models
    Ranjan Srivastava; Fiscal Year: 2009
  9. CANDIDA ALBICANS SURFACE ANTIGENS
    Jim Cutler; Fiscal Year: 2006
  10. MSM Multiscale Modeling of the Heart in Cardiovascular
    DANIEL BEARD; Fiscal Year: 2007

Detail Information

Publications193 found, 100 shown here

  1. ncbi cDNA cloning and expression analysis of new members of the mammalian F-box protein family
    G P Ilyin
    INSERM U522, Hopital Pontchaillou, Rennes, France
    Genomics 67:40-7. 2000
    ..Specifically, FBS and FBWD4 proteins contain Sec7 and WD40-repeat domains, respectively. The C-terminal region of FBA shares similarity with bacterial protein ApaG while FBG2 shows homology with the F-box protein NFB42...
  2. pmc PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation
    Yutaka Shima
    Molecular Oncology Division, National Cancer Center Research Institute, Tokyo, Japan
    Mol Cell Biol 28:7126-38. 2008
    ..To clarify the role of PML in transcription regulation, we purified the PML complex and identified Fbxo3 (Fbx3), Skp1, and Cullin1 as novel components of this complex...
  3. pmc Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia
    Tunahan Cakir
    Department of Chemical Engineering, Bogazici University, 34342, Bebek, Istanbul, Turkey
    Theor Biol Med Model 4:48. 2007
    ..To simplify this task and make it more practicable, we undertook stoichiometric modeling of brain energy metabolism with the major aim of including the main interacting pathways in and between astrocytes and neurons...
  4. ncbi [Immunophenotypic features of acute myeloid leukemia with AML-1/ETO fusion gene]
    Jian Jun Zhang
    Flow Cytomertry Laboratory, Department of Laboratory Medical Examination, Guangdong Provincial People s Hospital, Guangzhou 510080, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:378-81. 2007
    AML-1/ETO fusion gene is the frequent genetic lesion described in FBA M(2) type acute myeloid leukemia (AML-M(2)) and is associated with a favourable prognosis...
  5. pmc Horizontal transfer of a eukaryotic plastid-targeted protein gene to cyanobacteria
    Matthew B Rogers
    Canadian Institute for Advanced Research, Department of Botany, University of British Columbia, Vancouver, BC, Canada
    BMC Biol 5:26. 2007
    ..In particular, gene flow from eukaryotes to prokaryotes is rarely documented with strong support, which is unusual since prokaryotic genomes appear to readily accept foreign genes...
  6. ncbi Characterization of recombinant fructose-1,6-bisphosphate aldolase from Methylococcus capsulatus Bath
    O N Rozova
    Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
    Biochemistry (Mosc) 75:892-8. 2010
    The gene fba from the thermotolerant obligate methanotroph Methylococcus capsulatus Bath was cloned and expressed in Escherichia coli BL21(DE3)...
  7. ncbi Fructose-1,6-bisphosphate aldolases in amitochondriate protists constitute a single protein subfamily with eubacterial relationships
    Lidya Sánchez
    The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Gene 295:51-9. 2002
    Sequences of putative fructose-1,6-bisphospate aldolases (FBA) in five amitochondriate unicellular eukaryotes, the diplomonads Giardia intestinalis (published earlier) and Spironucleus barkhanus, the pelobiont Mastigamoeba balamuthi,the ..
  8. ncbi [Reliability of fetal pulse oximetry for the detection of fetal acidosis]
    B Seelbach-Göbel
    Klinik fur Frauenheilkunde und Geburtshilfe, St Hedwig Perinatalzentrum, Krankenhaus der Barmherzigen Bruder, Lehrstuhl der Universität Regensburg, Schwerpunkt Geburtshilfe, Regensburg
    Z Geburtshilfe Neonatol 209:43-50. 2005
    ..In all cases fetal blood pH and base excess were determined repeatedly by fetal blood analysis (FBA)...
  9. pmc Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans
    James S McCarthy
    University of Western Australia, Department of Medicine, Fremantle Hospital, Fremantle, Western Australia, Australia
    Infect Immun 70:851-8. 2002
    ..an open reading frame of 363 amino acids encoding the glycolytic enzyme fructose 1,6 bisphosphate aldolase (Ov-fba-1)...
  10. ncbi Archaeal fructose-1,6-bisphosphate aldolases constitute a new family of archaeal type class I aldolase
    B Siebers
    Department of Microbiology, Universitat Essen, 45117 Essen, Germany
    J Biol Chem 276:28710-8. 2001
    ..For enzymatic studies the fba genes of T. tenax and P. furiosus were expressed in Escherichia coli...
  11. doi Proteome-based physiological analysis of the metabolically engineered succinic acid producer Mannheimia succiniciproducens LPK7
    Jeong Wook Lee
    Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering BK21 Program, BioProcess Engineering Research Center, KAIST, 335 Gwahangno, Yuseong Gu, Daejeon 305 701, Republic of Korea
    Bioprocess Biosyst Eng 33:97-107. 2010
    ..Ppa, SerS, ProS, Pnp, PotD, MalK, RbsB, and TbpA), pyruvate metabolism (AceF and Lpd), glycolysis (GapA, Pgk, Fba, and TpiA), and amino acid biosynthesis (Asd, DapA, DapD, Gdh, ArgD, and ArgG) varied significantly in the LPK7 ..
  12. ncbi Nuclear transfer protocol affects messenger RNA expression patterns in cloned bovine blastocysts
    C Wrenzycki
    Department of Biotechnology, Institut für Tierzucht und Tierverhalten FAL, Mariensee, 31535 Neustadt, Germany
    Biol Reprod 65:309-17. 2001
    ..In experiment 1, employing either FBA (fusion before activation) or AFS (fusion and activation simultaneously) to generate NT blastocysts, Hsp mRNAs were ..
  13. ncbi Inhaled foreign bodies: management according to early or late presentation
    Sameh Ibrahim Sersar
    Cardiothoracic Surgery, Mansoura University, 35516, Egypt
    Eur J Cardiothorac Surg 28:369-74. 2005
    ..aspirated foreign body (AFB), to evaluate the factors associated with delayed diagnosis of foreign body aspiration (FBA) in children and to compare clinical, radiological and bronchoscopic findings in the patients with suspected FBA...
  14. doi Foreign body aspiration in children: the value of diagnostic criteria
    Gursu Kiyan
    Marmara University School of Medicine, Department of Pediatric Surgery, Tophanelioglu cad 13 15, Altunizade Uskudar, 34662 Istanbul, Turkey
    Int J Pediatr Otorhinolaryngol 73:963-7. 2009
    Foreign body aspiration (FBA) is a serious problem in children. While bronchoscopy should be performed in all patients with aspiration; patients without aspiration should be carefully excluded to avoid an unnecessary bronchoscopy...
  15. ncbi The antigen receptor (NCCRP-1) on catfish and zebrafish nonspecific cytotoxic cells belongs to a new gene family characterized by an F-box-associated domain
    Liliana Jaso-Friedmann
    Department of Medical Microbiology and Parasitology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602 7386, USA
    J Mol Evol 54:386-95. 2002
    ..present in NCCRP-1) and an extremely conserved C-terminal region that has been termed the F-box-associated domain (FBA). The FBA is currently of unknown function...
  16. pmc Recruitment of complement factor H-like protein 1 promotes intracellular invasion by group A streptococci
    Vinod Pandiripally
    Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City 66160, USA
    Infect Immun 71:7119-28. 2003
    ..b>Fba is an FHL-1 and FH binding protein expressed on the surface of the human pathogenic bacterium, Streptococcus ..
  17. pmc Modeling Lactococcus lactis using a genome-scale flux model
    Ana Paula Oliveira
    Fluxome Sciences A S, Søltofts Plads, Building 223, DK 2800 Kgs Lyngby, Denmark
    BMC Microbiol 5:39. 2005
    ..Flux balance analysis (FBA) and minimization of metabolic adjustment (MOMA) were used as modeling frameworks.
  18. ncbi Inhaled foreign bodies: presentation, management and value of history and plain chest radiography in delayed presentation
    Sameh Ibrahim Sersar
    Department of Cardiothoracic Surgery, Faculty of Medicine, Mansoura University, 35516 Mansoura, Egypt
    Otolaryngol Head Neck Surg 134:92-9. 2006
    ..on the outcome of the procedure and to evaluate the factors associated with delayed diagnosis of FB aspiration (FBA) in children; and to compare clinical, radiologic and bronchoscopic findings in the patients with suspected FB ..
  19. pmc Metabolic reconstruction and modeling of nitrogen fixation in Rhizobium etli
    Osbaldo Resendis-Antonio
    Bioengineering Department, University of California San Diego, La Jolla, California, USA
    PLoS Comput Biol 3:1887-95. 2007
    ..Flux balance analysis (FBA) was performed, and the predicted active metabolic pathways agreed qualitatively with experimental observations...
  20. pmc Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology
    Jacek Puchałka
    Synthetic and Systems Biology Group, Helmholtz Center for Infection Research HZI, Braunschweig, Germany
    PLoS Comput Biol 4:e1000210. 2008
    ..putida KT2440. Network reconstruction and flux balance analysis (FBA) enabled definition of the structure of the metabolic network, identification of knowledge gaps, and pin-pointing ..
  21. doi Management strategies in foreign-body aspiration
    Paola Zaupa
    Department of Pediatric Surgery, Medical University of Graz, Austria, Europa paola zaupa meduni graz at
    Indian J Pediatr 76:157-61. 2009
    ..management algorithm to ensure effective teamwork in decreasing morbidity and mortality in pediatric Foreign-Body Aspirations (FBA). Furthermore, the role of flexible bronchoscopy when compared to rigid bronchoscopy in FBA was evaluated.
  22. pmc Plasmid-dependent methylotrophy in thermotolerant Bacillus methanolicus
    Trygve Brautaset
    Department of Biotechnology, Norwegian University of Science and Technology, N 7491 Trondheim SINTEF Applied Chemistry, SINTEF, N 7043 Trondheim, Norway
    J Bacteriol 186:1229-38. 2004
    ..ribulose-5-phosphate 3-epimerase; tkt, encoding transketolase; glpX, encoding fructose-1,6-bisphosphatase; and fba, encoding fructose-1,6-bisphosphate aldolase) with deduced roles in methanol assimilation via the ribulose ..
  23. pmc The global repressor SugR controls expression of genes of glycolysis and of the L-lactate dehydrogenase LdhA in Corynebacterium glutamicum
    Verena Engels
    Institute of Biotechnology I, Research Center Juelich, Juelich, Germany
    J Bacteriol 190:8033-44. 2008
    ..regions of genes of the glycolytic enzymes 6-phosphofructokinase (pfkA), fructose-1,6-bisphosphate aldolase (fba), enolase (eno), pyruvate kinase (pyk), and NAD-dependent L-lactate dehydrogenase (ldhA)...
  24. ncbi The heterodox nature of "Turban Pins" in foreign body aspiration; the central anatolian experience
    Melih Kaptanoglu
    Department of Thoracic Surgery, Cumhuriyet University, Sivas, Turkiye
    Int J Pediatr Otorhinolaryngol 71:553-8. 2007
    ..The aim of this study is to determine the age and sex distribution and the nature of aspirated foreign bodies (FBs). We also compared Turban Pins (TP) with other FBs and discussed the extracting techniques...
  25. ncbi Multivalent II [beta-D-Galp-(1-->4)-beta-D-GlcpNAc] and Talpha [beta-D-Galp-(1-->3)-alpha-D-GalpNAc] specific Moraceae family plant lectin from the seeds of Ficus bengalensis fruits
    Biswajit Singha
    Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India
    Carbohydr Res 342:1034-43. 2007
    ..bengalensis agglutinin (FBA)...
  26. pmc Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis
    Scott D Pegan
    Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, IL 60607, USA
    J Mol Biol 386:1038-53. 2009
    ..tuberculosis. The class IIa fructose 1,6-bisphosphate aldolase (FBA) enzyme from M. tuberculosis (MtFBA) has been proposed as one such target since it is upregulated in latent TB...
  27. doi Genetic modification of flux for flux prediction of mutants
    Quanyu Zhao
    Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, 680 4 Kawazu, Iizuka, Fukuoka, Japan
    Bioinformatics 25:1702-8. 2009
    ..Some algorithms including flux balance analysis (FBA) and minimization of metabolic adjustment (MOMA) predict a flux distribution from a stoichiometric matrix in the ..
  28. doi The moonlighting protein fructose-1, 6-bisphosphate aldolase of Neisseria meningitidis: surface localization and role in host cell adhesion
    Sarfraz A Tunio
    Molecular Bacteriology and Immunology Group, Institute of Infection, Immunity and Inflammation, Centre for Biomolecular Sciences, University of Nottingham, Nottingham NG7 2RD, UK
    Mol Microbiol 76:605-15. 2010
    Fructose-1, 6-bisphosphate aldolases (FBA) are cytoplasmic glycolytic enzymes, which despite lacking identifiable secretion signals, have also been found localized to the surface of several bacteria where they bind host molecules and ..
  29. doi Kinetics independent spectrometric analysis using non-linear calibration modelling and exploitation of concentration gradients generated by a flow-batch system for albumin and total protein determination in blood serum
    Margarida C Souza
    Universidade Federal do Amazonas, Instituto de Ciências Exatas e Tecnologia, Brazil
    Talanta 82:1027-32. 2010
    ..It uses a non-linear calibration model that explores concentration gradients generated by a flow-batch analyser (FBA) for the samples, dye, and the single standard solution...
  30. ncbi Cyanophora paradoxa: nucleotide sequence and phylogeny of the nucleus encoded muroplast fructose-1,6-bisphosphate aldolase
    A A Nickol
    ZMBP, Pflanzenphysiologie, , Germany
    Z Naturforsch C 55:991-1003. 2000
    ..isolation of a clone encoding the nucleus-encoded muroplast class-II fructose-1,6-bisphosphate aldolase (class-II FBA). Its nucleotide sequence was determined...
  31. ncbi Comparing flux balance analysis to network expansion: producibility, sustainability and the scope of compounds
    Kai Kruse
    Theoretical Biophysics, Insitute for Biology, Humboldt University, Berlin, Germany
    Genome Inform 20:91-101. 2008
    ..The producibility of metabolites from available resources is investigated systematically using flux balance analysis (FBA) and network expansion...
  32. ncbi Laryngeal foreign body mistreated as recurrent laryngitis and croup for one year
    Sinan Atmaca
    Department of Otolaryngology, Ondokuz Mayis University Faculty of Medicine, Samsun, Turkey
    Turk J Pediatr 51:65-6. 2009
    Foreign body aspiration (FBA) is a common, dangerous problem among children of all ages...
  33. doi Sputum eosinophilia, airway hyperresponsiveness and airway narrowing in young adults with former asthma
    Johsuke Hara
    Respiratory Medicine, Cellular Transplantation Biology, Kanazawa University Graduate School of Medicine, Ishikawa, Japan
    Allergol Int 57:211-7. 2008
    ..30-80% of outgrown asthma subjects develop symptoms again later in life. We investigated inflammation and function of lower airway in adolescents with former asthma...
  34. ncbi Tracheobronchial foreign bodies in children: importance of accurate history and plain chest radiography in delayed presentation
    B Tokar
    Departments of Paediatric Surgery and Radiology, Osmangazi University Faculty of Medicine, Eskisehir, Turkey
    Clin Radiol 59:609-15. 2004
    To evaluate the factors associated with delayed diagnosis of foreign body aspiration (FBA) in children and to compare clinical, radiological and bronchoscopic findings in the patients with suspected FBA.
  35. ncbi Thin-section axial multidetector computed tomography and multiplanar reformatted imaging of children with suspected foreign-body aspiration: Is virtual bronchoscopy overemphasized?
    M Kocaoglu
    Department of Radiology, Gulhane Military Medical School, Etlik, Ankara, Turkey
    Acta Radiol 47:746-51. 2006
    ..computed tomography (MDCT)-assisted virtual bronchoscopy (VB) to axial MDCT and multiplanar reformatted (MPR) imaging with respect to conventional bronchoscopy in the evaluation of children with suspected foreign-body aspiration (FBA).
  36. ncbi Late diagnosis of foreign body aspiration in children with chronic respiratory symptoms
    F Karakoc
    Division of Pediatric Pulmonology, Marmara University, Istanbul, Turkey
    Int J Pediatr Otorhinolaryngol 71:241-6. 2007
    ..Children with undiagnosed and retained foreign bodies (FBs) may present with persistent respiratory symptoms. Delayed diagnosis is an important problem in developing countries and several factors affect the delay...
  37. pmc Understanding the adaptive growth strategy of Lactobacillus plantarum by in silico optimisation
    Bas Teusink
    Top Institute Food and Nutrition WCFS, Wageningen, The Netherlands
    PLoS Comput Biol 5:e1000410. 2009
    ..Hence, previous attempts to use FBA to predict metabolic fluxes in Lactobacillus plantarum failed, as this lactic acid bacterium produces lactate, even ..
  38. ncbi The antibiotic streptomycin assessed in a battery of in vitro tests for reproductive toxicology
    K Lemeire
    EggCentris NV, Z 1 Researchpark 310, B 1731 Zellik, Belgium
    Toxicol In Vitro 21:1348-53. 2007
    ..The follicle bio-assay (FBA) is a multiparametric long-term follicle culture system mimicking ovarian function; in vitro fertilisation (IVF) of ..
  39. ncbi Data reconciliation and parameter estimation in flux-balance analysis
    Arvind U Raghunathan
    Department of Chemical Engineering, Doherty Hall, 5000 Forbes Avenue, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Biotechnol Bioeng 84:700-9. 2003
    Flux blance analysis (FBA) has been shown to be a very effective tool to interpret and predict the metabolism of various microorganisms when the set of available measurements is not sufficient to determine the fluxes within the cell...
  40. ncbi Thermodynamic constraints for biochemical networks
    Daniel A Beard
    Biotechnology and Bioengineering Center, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Theor Biol 228:327-33. 2004
    ..Flux balance analysis (FBA) is based on the constraint of mass conservation; energy balance analysis (EBA) is based on non-equilibrium ..
  41. pmc Phenological responses to temperature of an annual and a perennial Lesquerella species
    Liliana B Windauer
    Departamento de Producción Vegetal, Faculdad de Agronomía, Universidad de Bunos Aires, Argentina
    Ann Bot 94:139-44. 2004
    ..The objective of this study was to examine differences in the phenology of L. fendleri and L. mendocina and in the response to temperature in both vegetative and reproductive phases...
  42. ncbi Extracellular matrix remodeling in children with airway foreign-body aspiration
    Lan Fang Tang
    Department of Respiratory Medicine, Zhejiang University Children s Hospital, School of Medicine, Zhugan Xiang, Hangzhou, China
    Pediatr Pulmonol 38:140-5. 2004
    ..of this study was to observe extracellular matrix remodeling in children with airway foreign-body aspiration (FBA) by detecting the expression of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of matrix metalloproteinase-1 (..
  43. pmc Glycolytic enzymes associated with the cell surface of Streptococcus pneumoniae are antigenic in humans and elicit protective immune responses in the mouse
    E Ling
    Pediatric Infectious Disease Unit, Soroka University Medical Center and the Department of Microbiology and Immunology, Ben Gurion University of the Negev, Beer Sheva, Israel
    Clin Exp Immunol 138:290-8. 2004
    ..Two immunogenic proteins, fructose-bisphosphate aldolase (FBA) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and a control protein with known low immunogenicity, heat ..
  44. ncbi Preparation of 18F-human serum albumin: a simple and efficient protein labeling method with 18F using a hydrazone-formation method
    Young Soo Chang
    Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea
    Bioconjug Chem 16:1329-33. 2005
    ..Here, we report a novel and simple method which includes the preparation of [18F]fluorobenzaldehyde ([18F]FBA) and successive conjugation with hydrazinonicotinic acid-human serum albumin conjugate (HYNIC-HSA) via hydrazone ..
  45. ncbi Flux balance analysis in the era of metabolomics
    Jong Min Lee
    Department of Biomedical Engineering, University of Virginia, PO Box 800759, Charlottesville, VA 22908, USA
    Brief Bioinform 7:140-50. 2006
    Flux balance analysis (FBA) has emerged as an effective means to analyse biological networks in a quantitative manner...
  46. ncbi Analysis of enzymopathies in the human red blood cells by constraint-based stoichiometric modeling approaches
    Saliha Durmuş Tekir
    Department of Chemical Engineering, Bogazici University, 34342 Bebek Istanbul, Turkey
    Comput Biol Chem 30:327-38. 2006
    ..For the normal RBC metabolism, flux balance analysis (FBA) is performed via optimization of various alternative objective functions, and the maximization of production of ..
  47. ncbi The effect of activation treatments on the development of reconstructed bovine oocytes
    P C Shen
    Department of Animal Science, National Pingtung University of Science and Technology, Pingtung 912, Taiwan, ROC
    Anim Reprod Sci 106:1-12. 2008
    ..05). Reconstructed oocytes activated 4h after fusion (fusion before activation, FBA) had a higher blastocyst rate than those oocytes activated immediately after electrofusion (fusion and activation ..
  48. ncbi Effects of prolonged exposure to alkaline pH on Enterococcus faecalis survival and specific gene transcripts
    O K Appelbe
    Department of Cariology, Restorative Sciences and Endodontics, The University of Michigan, School of Dentistry, MI 48109, USA
    Oral Microbiol Immunol 22:169-74. 2007
    ..We investigated the survival and gene expression of E. faecalis maintained in alkaline media...
  49. pmc Differential expression of Haemophilus parasuis genes in response to iron restriction and cerebrospinal fluid
    Devon S Metcalf
    Department of Pathobiology, University of Guelph, Guelph, Ontario
    Can J Vet Res 71:181-8. 2007
    ..polymerase chain reaction, we found that homologues of genes encoding fructose bisphosphate aldolase (fba), adenylosuccinate synthetase (purA), 2',3'-cyclic nucleotide phosphodiesterase (cpdB), lipoprotein signal ..
  50. pmc Photosensitivity in Smith-Lemli-Opitz syndrome: a flux balance analysis of altered metabolism
    Bell Raj Eapen
    Kaya Skin Clinic, Dubai, UAE
    Bioinformation 2:78-82. 2007
    ..A Flux Balance Analysis (FBA) has been carried out using the software CellNetAnalyzer or FluxAnalyzer to gain insight into the probable effects ..
  51. doi Effect of cement selection and finishing technique on marginal opening of cast gold inlays
    Charles V Farrell
    Department of Restorative Dentistry, School of Dentistry, University of Washington, Seattle, WA 98225 4035, USA
    J Prosthet Dent 99:287-92. 2008
    ..With increasing interest in using resin and resin-modified glass ionomer cements for this purpose, marginal adaptation with use of these newer cements must be assessed...
  52. doi "Severe" wear challenge to 36 mm mechanically enhanced highly crosslinked polyethylene hip liners
    J G Bowsher
    Department of Orthopaedics, Loma Linda University Medical Center, Loma Linda, California 92354, USA
    J Biomed Mater Res B Appl Biomater 86:253-63. 2008
    ..in volumetric wear a 13% reduction in wear particle size and a 27% reduction in Functional Biological Activity (FBA) compared to our control...
  53. ncbi A flow-batch analyzer with piston propulsion applied to automatic preparation of calibration solutions for Mn determination in mineral waters by ET AAS
    Luciano F Almeida
    Universidade Federal de Pernambuco, CCEN, Departamento de Quimica Fundamental, Brazil
    Talanta 73:906-12. 2007
    ..Flow-batch analyzers (FBA) have been successfully applied to implement analytical procedures, such as: titrations, sample pre-treatment, ..
  54. doi Heat pretreatment alleviates UV-B toxicity in the cyanobacterium Anabaena doliolum: A proteomic analysis of cross tolerance
    Yogesh Mishra
    Center of Advanced Study in Botany, Banaras Hindu University, Varanasi, India
    Photochem Photobiol 85:824-33. 2009
    ..phycobilisome core component (PBS-CC), iron superoxide dismutase (Fe-SOD), fructose-1,6-bisphosphate aldolase (FBA), nucleoside diphosphate kinase (NDPK), phosphoribulokinase (PRK) and ribulose-1,5-bisphosphate carboxylase/..
  55. pmc Contorted and ordinary body postures in the human brain
    Emily S Cross
    School of Psychology, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    Exp Brain Res 204:397-407. 2010
    ..of body representation implicates several brain regions including extrastriate and fusiform body areas (EBA and FBA), superior temporal sulcus (STS), inferior frontal gyrus (IFG) and inferior parietal lobule (IPL)...
  56. pmc Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models
    Nathan E Lewis
    Department of Bioengineering, University of California San Diego, La Jolla, CA 92093 0412, USA
    Mol Syst Biol 6:390. 2010
    ..of adaptive evolution at exponential growth, Escherichia coli grows as predicted using flux balance analysis (FBA) on genome-scale metabolic models (GEMs)...
  57. doi Brillouin amplification in phase coherent transfer of optical frequencies over 480 km fiber
    O Terra
    Physikalisch Technische Bundesanstalt, Bundesallee 100, 38116 Braunschweig, Germany
    Opt Express 18:16102-11. 2010
    We describe the use of fiber Brillouin amplification (FBA) for the coherent transmission of optical frequencies over a 480 km long optical fiber link...
  58. doi Theoretical predictions for ionization cross sections of DNA nucleobases impacted by light ions
    C Champion
    Laboratoire de Physique Moléculaire et des Collisions, ICPMB FR CNRS 2843, Institut de Physique, Universite Paul Verlaine Metz, 1 Bd Arago, 57078 Metz Cedex 3, France
    Phys Med Biol 55:6053-67. 2010
    ..The calculations are performed within the first-order Born approximation (FBA) with biological targets described at the restricted Hartree-Fock level with geometry optimization...
  59. doi Angiotensin-II-directed glomerulosa cell function in fetal adrenal cells
    W E Rainey
    Department of Obstetrics and Gynecology, The Green Center for Reproductive Biology Sciences, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 72535 9032, USA
    J Steroid Biochem Mol Biol 43:847-54. 1992
    ..Herein, we used primary cultures of fetal bovine adrenal (FBA) cells to examine the effects of A-II on aldosterone production and the expression of aldosterone synthase ..
  60. doi Software applications toward quantitative metabolic flux analysis and modeling
    Thomas Dandekar
    Department of Bioinformatics, Biocenter, University of Wuerzburg, Am Hubland, 97074 Wuerzburg, Germany Tel 49 931 318 4551 Fax 49 931 318 4552
    Brief Bioinform 15:91-107. 2014
    ..Metabolic modeling elucidates in silico all the possible flux pathways (flux balance analysis, FBA) and predicts the actual fluxes under a given situation, further refinement of these models is possible by ..
  61. pmc A comprehensive analysis of interaction and localization of Arabidopsis SKP1-like (ASK) and F-box (FBX) proteins
    Hirofumi Kuroda
    Plant Functional Genomics Research Group, Plant Science Center, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan
    PLoS ONE 7:e50009. 2012
    ..a preference for interacting with ASK proteins depending on the domains they contain such as the FBX-associated (FBA) domain, the Kelch domain and leucine rich repeat (LRR)...
  62. doi Tracheobronchial Foreign Body Aspirations: Lessons Learned From a 10-year Audit
    Jai Kumar Mahajan
    Department of Pediatric Surgery, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    J Bronchology Interv Pulmonol 18:223-8. 2011
    BACKGROUND : Foreign body aspirations (FBA) in the tracheobronchial tree must be suspected in children who present with a witnessed history of choking or respiratory distress of sudden onset and asymmetric breath sounds, even in the ..
  63. doi Fully automated synthesis of 4-[18F]fluorobenzylamine based on borohydride/NiCl2 reduction
    Jenilee Way
    Department of Oncology, University of Alberta, Edmonton AB, T6G 1Z2, Canada
    Nucl Med Biol 40:430-6. 2013
    4-[(18)F]Fluorobenzylamine ([(18)F]FBA) is an important building block for the synthesis of (18)F-labeled compounds...
  64. doi Modelling metabolic CO₂ evolution--a fresh perspective on respiration
    Lee J Sweetlove
    Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, UK
    Plant Cell Environ 36:1631-40. 2013
    ..a mechanistic model of respiration is lacking, and so here we explore the potential for flux balance analysis (FBA) to predict cellular CO₂ evolution rates...
  65. doi On the limitations of standard statistical modeling in biological systems: a full Bayesian approach for biology
    Jaime Gómez-Ramirez
    Okayama University, Biomedical Engineering Laboratory, 3 1 1 Tsushimanaka, Kita ku 700 8530, Japan Universidad Politécnica de Madrid, José Gutiérrez Abascal, 2, Madrid 28006, Spain Electronic address
    Prog Biophys Mol Biol 113:80-91. 2013
    ..We introduce a full Bayesian approach (FBA), a theoretical framework to study biological function, in which probability distributions are conditional on ..
  66. pmc Flux imbalance analysis and the sensitivity of cellular growth to changes in metabolite pools
    Ed Reznik
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts, United States of America
    PLoS Comput Biol 9:e1003195. 2013
    Stoichiometric models of metabolism, such as flux balance analysis (FBA), are classically applied to predicting steady state rates - or fluxes - of metabolic reactions in genome-scale metabolic networks...
  67. pmc Targeting F box protein Fbxo3 to control cytokine-driven inflammation
    Rama K Mallampalli
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213
    J Immunol 191:5247-55. 2013
    ..We discovered that a ubiquitin E3 ligase F box component, termed Fbxo3, potently stimulates cytokine secretion from human inflammatory cells by mediating the degradation of the TRAF ..
  68. doi Incorporation of a triglutamyl spacer improves the biodistribution of synthetic affibody molecules radiofluorinated at the N-terminus via oxime formation with (18)F-4-fluorobenzaldehyde
    Daniel Rosik
    Division of Protein Technology, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden
    Bioconjug Chem 25:82-92. 2014
    ..The use of oxime formation between an aminooxy-functionalized peptide and (18)F-fluorobenzaldehyde ((18)F-FBA) is a promising way of radiolabeling of targeting peptides...
  69. pmc Incorporation of flexible objectives and time-linked simulation with flux balance analysis
    Elsa W Birch
    Chemical Engineering, Stanford University, Stanford, CA 94305, USA
    J Theor Biol 345:12-21. 2014
    We present two modifications of the flux balance analysis (FBA) metabolic modeling framework which relax implicit assumptions of the biomass reaction...
  70. pmc Structural and functional characterization of methicillin-resistant Staphylococcus aureus's class IIb fructose 1,6-bisphosphate aldolase
    Glenn C Capodagli
    Department of Chemistry and Biochemistry, University of Denver, Denver, Colorado 80208, United States
    Biochemistry 53:7604-14. 2014
    ..Regrettably, scarce biochemical data and no structural data are currently available for the class II FBA found in MRSA (SaFBA)...
  71. doi Is the whole the sum of its parts? Configural processing of headless bodies in the right fusiform gyrus
    Denise Soria Bauser
    Institute of Cognitive Neuroscience, Department of Neuropsychology, Faculty of Psychology, Ruhr University Bochum, Universitatsstrase 150, 44780 Bochum, Germany Electronic address
    Behav Brain Res 281:102-10. 2015
    ..The right fusiform body area (FBA) showed a preference for whole bodies compared to the sum of their parts as the right and left fusiform face area ..
  72. pmc Hepatocytes maintain greater fluorescent bile acid accumulation and greater sensitivity to drug-induced cell death in three-dimensional matrix culture
    John W Murray
    Department of Anatomy and Structural Biology, Division of Gastroenterology and Liver Diseases, Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York
    Physiol Rep 2:. 2014
    ..Hepatocytes were found to accumulate fluorescent bile acid (FBA) at significantly higher levels than the related fluorophores, carboxyfluorescein diacetate, (4...
  73. doi How Parents' Lack of Awareness Could Be Associated With Foreign Body Aspiration in Children
    Alkistis Adramerina
    From the Department of Medical Pediatrics, General Hospital of Drama, Drama, Greece
    Pediatr Emerg Care 32:98-100. 2016
    Foreign body aspiration (FBA) in preschool children is a worldwide challenging clinical problem that can result in life-threatening complications. Three cases of FBA in preschool children are presented...
  74. doi Fast-SL: an efficient algorithm to identify synthetic lethal sets in metabolic networks
    Aditya Pratapa
    Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences and
    Bioinformatics 31:3299-305. 2015
    ..synthetic lethal genes in genome-scale metabolic networks have built on the framework of flux balance analysis (FBA), extending it either to exhaustively analyze all possible combinations of genes or formulate the problem as a bi-..
  75. doi Genome-scale modelling of microbial metabolism with temporal and spatial resolution
    Michael A Henson
    Department of Chemical Engineering, University of Massachusetts, Amherst, MA 01003, U S A
    Biochem Soc Trans 43:1164-71. 2015
    ..The extension of flux balance analysis (FBA) to account for both temporal and spatial variations in the environment is termed spatiotemporal FBA (SFBA)...
  76. doi Characterizing the optimal flux space of genome-scale metabolic reconstructions through modified latin-hypercube sampling
    Neha Chaudhary
    Laboratory of Genetic Engineering and Molecular Biology, School of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, India
    Mol Biosyst 12:994-1005. 2016
    ..Metabolic Reconstructions (GSMRs), along with optimization-based methods, predominantly Flux Balance Analysis (FBA) and its derivatives, are widely applied for assessing and predicting the behavior of metabolic networks upon ..
  77. doi Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice
    Shirin Elhaik Goldman
    Pediatric Infectious Disease Unit, Soroka University Medical Center, Beer Sheva 84100, Israel
    Int J Mol Med 37:1127-38. 2016
    ..pneumoniae. Fructose-1,6-bisphosphate aldolase (FBA) is a glycolytic enzyme, which was found to localize to the bacterial surface, where it functions as an adhesin...
  78. pmc Whole Cell Modeling: From Single Cells to Colonies
    John A Cole
    Department of Physics, University of Illinois, Urbana Champaign, 1110 West Green Street, Urbana, IL 61801 USA
    Isr J Chem 54:1219-1229. 2014
    ..in models of whole cells; the latter to the development of a method we call population flux balance analysis (FBA)...
  79. pmc Metabolic constraints for a novel symbiosis
    Megan E S Sørensen
    Department of Biology, University of York, York YO10 5GG, UK
    R Soc Open Sci 3:150708. 2016
    ..Here, we apply metabolic modelling, using flux balance analysis (FBA), to predict the metabolic adaptations necessary for this previously free-living symbiont to transition to the ..
  80. doi A systems biology approach to reconcile metabolic network models with application to Synechocystis sp. PCC 6803 for biofuel production
    Reza Mohammadi
    Laboratory of Systems Biology and Bioinformatics LBB, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    Mol Biosyst 12:2552-61. 2016
    ..Then, after modeling for biofuel production, the results from flux balance analysis (FBA) disclosed an increased yield in biofuel production for ethanol, isobutanol, 3-methyl-1-butanol, 2-methyl-1-butanol,..
  81. pmc From DNA to FBA: How to Build Your Own Genome-Scale Metabolic Model
    Daniel A Cuevas
    Computational Science Research Center, San Diego State University, San Diego CA, USA
    Front Microbiol 7:907. 2016
    ..Flux-balance analysis (FBA), a linear programming technique that uses metabolic models to predict the phenotypic responses imposed by ..
  82. pmc Improved Metabolic Models for E. coli and Mycoplasma genitalium from GlobalFit, an Algorithm That Simultaneously Matches Growth and Non-Growth Data Sets
    Daniel Hartleb
    Institute for Computer Science and Cluster of Excellence on Plant Sciences, Heinrich Heine University, Dusseldorf, Germany
    PLoS Comput Biol 12:e1005036. 2016
    Constraint-based metabolic modeling methods such as Flux Balance Analysis (FBA) are routinely used to predict the effects of genetic changes and to design strains with desired metabolic properties...
  83. pmc Fructose 1,6-Bisphosphate Aldolase, a Novel Immunogenic Surface Protein on Listeria Species
    Marcelo Mendonça
    Laboratório de Imunologia Aplicada, Núcleo de Biotecnologia, Centro de Desenvolvimento Tecnológico, Universidade Federal de Pelotas, Pelotas, RS, Brazil
    PLoS ONE 11:e0160544. 2016
    ..In the present work, using mass spectrometry and genetic cloning, we show that fructose-1,6-bisphosphate aldolase (FBA) class II in Listeria species is the antigen target of the previously described mAb-3F8...
  84. pmc Metabolic modelling in a dynamic evolutionary framework predicts adaptive diversification of bacteria in a long-term evolution experiment
    Tobias Großkopf
    School of Life Sciences, University of Warwick, Coventry, UK
    BMC Evol Biol 16:163. 2016
    ..However, analysing these models via flux balance analysis (FBA) cannot predict many evolutionary outcomes including adaptive diversification, whereby an ancestral lineage ..
  85. pmc Differential Reinforcement of Other Behaviour for the Reduction of Severe Nail Biting
    Louise Heffernan
    Irish Centre of Behavioural Support and Research, Dublin, Ireland
    Behav Anal Pract 9:253-6. 2016
    ..A functional behaviour assessment (FBA) identified that the behaviour was maintained by automatic reinforcement...
  86. doi An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis
    Raffaele Simeoli
    Department of Pharmacy, University of Naples Federico II, Naples, Italy
    Br J Pharmacol . 2016
    ..The efficacy of a more palatable butyrate-releasing derivative, N-(1-carbamoyl-2-phenylethyl) butyramide (FBA), was evaluated in a mouse model of colitis induced by dextran sodium sulphate (DSS).
  87. ncbi Two new radiological findings to improve the diagnosis of bronchial foreign-body aspiration in children
    Guido Girardi
    Pediatric Pulmonary Section, Department of Pediatrics, Exequiel Gonzales Cortes Children s Hospital, University of Chile, Santiago, Chile
    Pediatr Pulmonol 38:261-4. 2004
    ..in the same hemithorax, and aeration within an area of atelectasis) in children with foreign-body aspiration (FBA). We performed a retrospective review of clinical characteristics and chest X-ray films of 133 children with FBA...
  88. doi Flux balance analysis of Chlorella sp. FC2 IITG under photoautotrophic and heterotrophic growth conditions
    Muthusivaramapandian Muthuraj
    Department of Biotechnology, Indian Institute of Technology Guwahati, Guwahati, 781039, Assam, India
    Photosynth Res 118:167-79. 2013
    ..In the present study, flux balance analysis (FBA) was carried out for an indigenous isolate Chlorella sp...
  89. ncbi Microscopic quantification of bacterial invasion by a novel antibody-independent staining method
    Franziska Agerer
    Zentrum für Infektionsforschung, Universitat Wurzburg, Rontgenring 11, 97070 Wurzburg, Germany
    J Microbiol Methods 59:23-32. 2004
    ..We describe a novel fluorescence staining protocol, called FITC-biotin-avidin (FBA) staining, which allows the differentiation between extracellular and intracellular bacteria and is independent of ..
  90. ncbi Complementary identification of multiple flux distributions and multiple metabolic pathways
    Dong Yup Lee
    Metabolic and Biomolecular Engineering National Research Laboratory, Korea Advanced Institute of Science and Technology, 373 1 Guseong dong, Yuseong Gu, Daejeon 305 701, Korea
    Metab Eng 7:182-200. 2005
    ..This approach judiciously integrates flux balance analysis (FBA) based on linear programming and the graph-theoretic method for determining reaction pathways...
  91. pmc Regulatory on/off minimization of metabolic flux changes after genetic perturbations
    Tomer Shlomi
    School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel
    Proc Natl Acad Sci U S A 102:7695-700. 2005
    ..are compared with previously suggested algorithms, minimization of metabolic adjustment, and flux balance analysis (FBA)...
  92. ncbi Synthesis and preclinical evaluation of a folic acid derivative labeled with 18F for PET imaging of folate receptor-positive tumors
    Andrea Bettio
    Department of Chemistry and Applied Biosciences of ETH, Center for Radiopharmaceutical Science of ETH, PSI, and USZ, Zurich, Switzerland
    J Nucl Med 47:1153-60. 2006
    Folic acid was linked regioselectively through its alpha- and gamma-carboxyl groups to 4-fluorobenzylamine (FBA), and the alpha- and gamma-FBA-folate regioisomers were evaluated for their ability to bind to folate receptor-positive cells...
  93. doi The methylotrophic Bacillus methanolicus MGA3 possesses two distinct fructose 1,6-bisphosphate aldolases
    Jessica Stolzenberger
    Faculty of Biology and CeBiTec, Bielefeld University, Bielefeld, Germany
    Microbiology 159:1770-81. 2013
    ..Fructose 1,6-bisphosphate aldolase (FBA), a key enzyme of glycolysis and gluconeogenesis, is encoded in the genome of B...
  94. doi Structure-based design and synthesis of novel dual-target inhibitors against cyanobacterial fructose-1,6-bisphosphate aldolase and fructose-1,6-bisphosphatase
    Ding Li
    Key Laboratory of Pesticide and Chemical Biology CCNU, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, China
    J Agric Food Chem 61:7453-61. 2013
    Cyanobacteria class II fructose-1,6-bisphoshate aldolase (Cy-FBA-II) and cyanobacteria fructose-1,6-bisphosphatase (Cy-FBPase) are two neighboring key regulatory enzymes in the Calvin cycle of the cyanobacteria photosynthesis system...
  95. pmc A model of an integrated immune system pathway in Homo sapiens and its interaction with superantigen producing expression regulatory pathway in Staphylococcus aureus: comparing behavior of pathogen perturbed and unperturbed pathway
    Namrata Tomar
    Machine Intelligence Unit, Indian Statistical Institute, Kolkata, India
    PLoS ONE 8:e80918. 2013
    ..Moreover, we have developed a formalism under Flux Balance Analysis (FBA) for the optimization of conflicting objective functions...
  96. doi Segregated flux balance analysis constrained by population structure/function data: the case of PHA production by mixed microbial cultures
    F Pardelha
    REQUIMTE CQFB, Chemistry Department, FCT Universidade Nova de Lisboa, 2829 516 Caparica, Portugal
    Biotechnol Bioeng 110:2267-76. 2013
    In this study we developed a segregated flux balance analysis (FBA) method to calculate metabolic flux distributions of the individual populations present in a mixed microbial culture (MMC)...
  97. pmc The ability of flux balance analysis to predict evolution of central metabolism scales with the initial distance to the optimum
    William R Harcombe
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 9:e1003091. 2013
    The most powerful genome-scale framework to model metabolism, flux balance analysis (FBA), is an evolutionary optimality model...
  98. pmc Plant F-box protein evolution is determined by lineage-specific timing of major gene family expansion waves
    Aura Navarro-Quezada
    Department of Stress and Developmental Biology, Leibniz Institute of Plant Biochemistry, Halle Saale, Germany
    PLoS ONE 8:e68672. 2013
    ..we asked whether the largest subfamily in Arabidopsis thaliana, which carries a C-terminal F-box associated domain (FBA proteins) shares evolutionary patterns and signatures of selection with other FBPs...
  99. doi A flow-batch analyzer using a low cost aquarium pump for classification of citrus juice with respect to brand
    Sueny Kêlia Barbosa Freitas
    Departamento de Quimica, Universidade Federal da Paraiba, CCEN, CP 5093, 58051 970 João Pessoa PB, Brazil
    Talanta 107:45-8. 2013
    This paper proposes a novel flow-batch analyzer (FBA), which employs a compact, low-cost aquarium air pump as an alternative to a peristaltic pump...
  100. doi Optimization of the solid-phase synthesis of [18F] radiolabeled peptides for positron emission tomography
    Jason B White
    Department of Biomedical Engineering, University of California, Davis, USA
    Appl Radiat Isot 70:2720-9. 2012
    ..selected for solid-phase radiolabeling of the model peptide VQAAIDYING with 4-[(18)F]fluorobenzoic acid ([(18)F]FBA). A wide range of radiochemical yields (18.8 ± 1.5% to 41.2 ± 5...
  101. doi Questions About Behavioral Function (QABF): adaptation and validation of the Spanish version
    David Simó-Pinatella
    Ramon Llull University, C Cister, 34, 08022 Barcelona, Spain
    Res Dev Disabil 34:1248-55. 2013
    ..These behaviors become a challenge for the families and for professionals. Functional behavioral assessment (FBA) is a method used to identify variables that influence or maintain challenging behaviors (CB) and aid in the ..

Research Grants11

  1. Hong Xin; Fiscal Year: 2014
    ..Strong evidences show that antibodies specific for the peptide Fba (derived from C. albicans cell surface protein fructose bisphosphate aldolase) and C...
  2. Targeting persistent M. tuberculosis through the inhibition of its aldolase
    Mary Jackson; Fiscal Year: 2010
    ..The search for alternative drug therapies has led to our interest in class II fructose-1,6-bisphosphate aldolase (FBA), a key enzyme of glycolysis/gluconeogenesis that was shown to be induced in M...
  3. Assay Development of M. tuberculosis class II aldolase
    Mary Jackson; Fiscal Year: 2010
    ..The search for alternative drug therapies has led to our interest in class II fructose-1, 6-bisphosphate aldolase (FBA), a key enzyme of glycolysis/gluconeogenesis that was shown to be induced in M...
  4. Beibei Chen; Fiscal Year: 2016
    ..In the process of studying bacterial sepsis, we discovere that an orphan ubiquitin E3 ligase subunit, termed FBXO3, is activated and sufficient to ubiquitinate and mediate proteasomal degradation of another relatively new ..
  5. Nonablative AlloSCT in Refractory Autoimmune Disease
    Mitchell Cairo; Fiscal Year: 2003
    ..specific aims include: 1) to determine the toxicity of RI conditioning with fludarabine, busulfan and alemtuzumab (FBA) followed by AIIoSCT; 2) to quantitate percent mixed and complete donor chimerism following FBA and AIIoSCT + DLI; ..
  6. THE FnA D REGION OF TENASCIN C AND NEURONAL GROWTH
    Sally Meiners; Fiscal Year: 2005
    ..Neurites demonstrate a strong preference for fbA-D when they are given a choice at an interface...
  7. Novel Data Capture and Assessment Technology for Autism
    RONALD OBERLEITNER; Fiscal Year: 2006
    ..evaluate a tool designed to support the collection of rich data for performing a Functional Behavior Assessment (FBA) in schools to support the development of intervention plans for children with special needs, specifically children ..
  8. Automatic Generation of Genome-scale Flux Balance Models
    Ranjan Srivastava; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Flux balance analysis (FBA) is proving to be a powerful tool for analyzing metabolic networks...
  9. CANDIDA ALBICANS SURFACE ANTIGENS
    Jim Cutler; Fiscal Year: 2006
    ....
  10. MSM Multiscale Modeling of the Heart in Cardiovascular
    DANIEL BEARD; Fiscal Year: 2007
    ..abstract_text> ..
  11. Analysis of Large-Scale Biochemical Systems
    DANIEL BEARD; Fiscal Year: 2007
    ..constraints on biochemical fluxes and [unreadable] concentration to augment the flux-balance analysis (FBA) approach...