COX3

Summary

Gene Symbol: COX3
Description: cytochrome c oxidase III
Alias: COIII, MTCO3, cytochrome c oxidase III, cytochrome c oxidase subunit III
Species: human

Top Publications

  1. ncbi Involvement of cytochrome c oxidase subunit III in energy coupling
    S Wu
    Department of Pathology, Medical College of Pennsylvania, Philadelphia 19102, USA
    Biochemistry 34:16298-305. 1995
  2. ncbi Identification of the YMN-1 antigen protein and biochemical analyses of protein components in the mitochondrial nucleoid fraction of the yeast Saccharomyces cerevisiae
    H Sato
    Department of Physics, Biology and Informatics, Faculty of Science, Yamaguchi University, Yamaguchi, 753 8512, Japan
    Protoplasma 219:51-8. 2002
  3. doi Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria
    Kenji Hikosaka
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    Mol Biol Evol 27:1107-16. 2010
  4. doi Technical report: immunofluorescence and TUNEL staining of celloidin embedded human temporal bone tissues
    Adam Markaryan
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Chicago, 5841 S Maryland Avenue, MC 1035, Chicago, IL 60637, United States
    Hear Res 241:1-6. 2008
  5. pmc Phylogenetic analysis of mitochondrial substitution rate variation in the angiosperm tribe Sileneae
    Daniel B Sloan
    Department of Plant and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden
    BMC Evol Biol 9:260. 2009
  6. doi Knock-down of the COX3 and COX17 gene expression of cytochrome c oxidase in the unicellular green alga Chlamydomonas reinhardtii
    Claire Remacle
    Department of Life Sciences, Institute of Botany, B22 University of Liege, 4000 Liege, Belgium
    Plant Mol Biol 74:223-33. 2010
  7. ncbi The analysis of the complete mitochondrial genome of Lecanicillium muscarium (synonym Verticillium lecanii) suggests a minimum common gene organization in mtDNAs of Sordariomycetes: phylogenetic implications
    Vassili N Kouvelis
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistemiopolis, Athens 157 01, Greece
    Fungal Genet Biol 41:930-40. 2004
  8. ncbi The highly reduced and fragmented mitochondrial genome of the early-branching dinoflagellate Oxyrrhis marina shares characteristics with both apicomplexan and dinoflagellate mitochondrial genomes
    Claudio H Slamovits
    Department of Botany, University of British Columbia, Vancouver, BC, Canada
    J Mol Biol 372:356-68. 2007
  9. ncbi Group-I introns in the cytochrome c oxidase genes of Dictyostelium discoideum: two related ORFs in one loop of a group-I intron, a cox1/2 hybrid gene and an unusually large cox3 gene
    S Ogawa
    Institute of Biological Sciences, University of Tsukuba, Tsukuba, Ibaraki 305, Japan
    Curr Genet 31:80-8. 1997
  10. doi The mitochondrial genome of a deep-sea bamboo coral (Cnidaria, Anthozoa, Octocorallia, Isididae): genome structure and putative origins of replication are not conserved among octocorals
    Mercer R Brugler
    Department of Biology, University of Louisiana at Lafayette, P O Box 42451, Lafayette, LA 70504, USA
    J Mol Evol 67:125-36. 2008

Research Grants

  1. The Hig1 protein family and the cytochrome c oxidase complex
    Rosemary A Stuart; Fiscal Year: 2012
  2. Protein-Facilitated Group I Intron Splicing
    Mark Caprara; Fiscal Year: 2006
  3. Mechanism of tRNA Import Into Trypanosome Mitochondria
    STEPHEN HAJDUK; Fiscal Year: 2009
  4. Function of mRNA Editing in Trypanosomes
    Stephen L Hajduk; Fiscal Year: 2010
  5. The Impact of HLA in Children Receiving HAART
    Akihiko Saitoh; Fiscal Year: 2008

Detail Information

Publications186 found, 100 shown here

  1. ncbi Involvement of cytochrome c oxidase subunit III in energy coupling
    S Wu
    Department of Pathology, Medical College of Pennsylvania, Philadelphia 19102, USA
    Biochemistry 34:16298-305. 1995
    The role of the conserved acidic residues of subunit III of cytochrome c oxidase (COIII) in energy transduction was investigated...
  2. ncbi Identification of the YMN-1 antigen protein and biochemical analyses of protein components in the mitochondrial nucleoid fraction of the yeast Saccharomyces cerevisiae
    H Sato
    Department of Physics, Biology and Informatics, Faculty of Science, Yamaguchi University, Yamaguchi, 753 8512, Japan
    Protoplasma 219:51-8. 2002
    ..In contrast, porin and cytochrome c oxidase subunit III (CoxIIIp) were not detected by immunoblotting in the mt-nucleoid fraction...
  3. doi Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria
    Kenji Hikosaka
    Laboratory of Malariology, International Research Center of Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
    Mol Biol Evol 27:1107-16. 2010
    ..in the form of a circular and/or tandemly repeated linear element of 6 kb, encoding only three protein genes (cox1, cox3, and cob). The closely related genera Babesia and Theileria also have small mt genomes (6...
  4. doi Technical report: immunofluorescence and TUNEL staining of celloidin embedded human temporal bone tissues
    Adam Markaryan
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Chicago, 5841 S Maryland Avenue, MC 1035, Chicago, IL 60637, United States
    Hear Res 241:1-6. 2008
    ..knowledge, successful immunofluorescence staining of type I collagen, immunofluorescence staining of cytochrome c oxidase subunit III (COX III), and TUNEL staining in archival human temporal bone tissues with confocal microscopy has ..
  5. pmc Phylogenetic analysis of mitochondrial substitution rate variation in the angiosperm tribe Sileneae
    Daniel B Sloan
    Department of Plant and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden
    BMC Evol Biol 9:260. 2009
    ..noctiflora is a recent and isolated evolutionary event. This assessment, however, is based on a very limited sampling of taxa within this diverse genus...
  6. doi Knock-down of the COX3 and COX17 gene expression of cytochrome c oxidase in the unicellular green alga Chlamydomonas reinhardtii
    Claire Remacle
    Department of Life Sciences, Institute of Botany, B22 University of Liege, 4000 Liege, Belgium
    Plant Mol Biol 74:223-33. 2010
    The COX3 gene encodes a core subunit of mitochondrial cytochrome c oxidase (complex IV) whereas the COX17 gene encodes a chaperone delivering copper to the enzyme...
  7. ncbi The analysis of the complete mitochondrial genome of Lecanicillium muscarium (synonym Verticillium lecanii) suggests a minimum common gene organization in mtDNAs of Sordariomycetes: phylogenetic implications
    Vassili N Kouvelis
    Department of Genetics and Biotechnology, Faculty of Biology, University of Athens, Panepistemiopolis, Athens 157 01, Greece
    Fungal Genet Biol 41:930-40. 2004
    ..mtDNA gene order could be detected, in two units, for all known Sordariomycetes namely nad1-nad4-atp8-atp6 and rns-cox3-rnl, which can be extended in Hypocreales, to nad4L-nad5-cob-cox1-nad1-nad4-atp8-atp6 and rns-cox3-rnl nad2-nad3, ..
  8. ncbi The highly reduced and fragmented mitochondrial genome of the early-branching dinoflagellate Oxyrrhis marina shares characteristics with both apicomplexan and dinoflagellate mitochondrial genomes
    Claudio H Slamovits
    Department of Botany, University of British Columbia, Vancouver, BC, Canada
    J Mol Biol 372:356-68. 2007
    ..the smallest gene complement known, with several rRNA fragments and only two protein coding genes, cox1 and a cob-cox3 fusion...
  9. ncbi Group-I introns in the cytochrome c oxidase genes of Dictyostelium discoideum: two related ORFs in one loop of a group-I intron, a cox1/2 hybrid gene and an unusually large cox3 gene
    S Ogawa
    Institute of Biological Sciences, University of Tsukuba, Tsukuba, Ibaraki 305, Japan
    Curr Genet 31:80-8. 1997
    ..4) also have a free-standing ORF in loop 1 and loop 2, respectively. These results show that these group-I introns and the intronic ORFs have evolved from the same ancestral origin, but that these ORFs have been propagated independently...
  10. doi The mitochondrial genome of a deep-sea bamboo coral (Cnidaria, Anthozoa, Octocorallia, Isididae): genome structure and putative origins of replication are not conserved among octocorals
    Mercer R Brugler
    Department of Biology, University of Louisiana at Lafayette, P O Box 42451, Lafayette, LA 70504, USA
    J Mol Evol 67:125-36. 2008
    ..octocoral mt genome, which has 12 genes transcribed on one strand and 5 genes on the opposite (cox2, atp8, atp6, cox3, trnM), in the bamboo coral genome a contiguous string of 5 genes (msh1, rnl, nad2, nad5, nad4) has undergone an ..
  11. doi Gene expression and immunohistochemistry in adipose tissue of HIV type 1-infected patients with nucleoside analogue reverse-transcriptase inhibitor-associated lipoatrophy
    M Sievers
    Department of Rheumatology and Clinical Immunology, Medizinische Universitatsklinik, Freiburg, Germany
    J Infect Dis 200:252-62. 2009
    ..Long-term use of both zidovudine (AZT) and stavudine (d4T) is associated with lipoatrophy, but it occurs possibly through different mechanisms...
  12. ncbi The mitochondrial genome of Acropora tenuis (Cnidaria; Scleractinia) contains a large group I intron and a candidate control region
    Madeleine J H van Oppen
    Biochemistry and Molecular Biology, James Cook University, Townsville, Queensland 4811, Australia
    J Mol Evol 55:1-13. 2002
    ..Finally, we provide evidence that the rns-cox3 intergenic region in A. tenuis may correspond to the mitochondrial control region of higher animals...
  13. ncbi The complete mitochondrial genome of the yeast Kluyveromyces thermotolerans
    Emmanuel Talla
    Unité de Génétique Moléculaire des Levures URA 2171 CNRS, UFR 927 Université PM Curie, Institut Pasteur, 25 rue du Docteur Roux, F 75724 Paris Cedex 15, France
    FEBS Lett 579:30-40. 2005
    ..It encodes, all on the same DNA strand, three subunits of cytochrome oxidase (COX1, COX2 and COX3), three subunits of ATP synthetase (ATP6, ATP8 and ATP9), the apocytochrome b (COB), the ribosomal protein VAR1, 24 ..
  14. pmc A genetic link between an mRNA-specific translational activator and the translation system in yeast mitochondria
    P Haffter
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Genetics 125:495-503. 1990
    Translation of the Saccharomyces cerevisiae mitochondrial mRNA encoding cytochrome c oxidase subunit III (coxIII) specifically requires the products of at least three nuclear genes, PET122, PET494 and PET54...
  15. pmc Functional interactions among two yeast mitochondrial ribosomal proteins and an mRNA-specific translational activator
    P Haffter
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Genetics 127:319-26. 1991
    Expression of the Saccharomyces cerevisiae mitochondrial gene coding cytochrome c oxidase subunit III is specifically activated at the level of translation by at least three nuclear genes, PET122, PET494 and PET54...
  16. pmc Specific translational activation by nuclear gene products occurs in the 5' untranslated leader of a yeast mitochondrial mRNA
    M C Costanzo
    Section of Genetics and Development, Cornell University, Ithaca, NY 14853
    Proc Natl Acad Sci U S A 85:2677-81. 1988
    Translation of the yeast mitochondrial mRNA encoding cytochrome c oxidase subunit III (coxIII) is specifically activated by the products of at least three nuclear genes, PET494, PET54, and PET122...
  17. ncbi Making the most of mitochondrial genomes--markers for phylogeny, molecular ecology and barcodes in Schistosoma (Platyhelminthes: Digenea)
    M Z Zarowiecki
    Wolfson Wellcome Biomedical Laboratories, Department of Zoology, Natural History Museum, Cromwell Road, London SW7 5BD, UK
    Int J Parasitol 37:1401-18. 2007
    ..mansoni. The genes nad1, nad4, nad5, cox1 and cox3 resolved phylogenies that were consistent with a benchmark phylogeny and in general, longer genes performed better ..
  18. pmc Two distinct, sequence-specific DNA-binding proteins interact independently with the major replication pause region of sea urchin mtDNA
    S A Qureshi
    Robertson Institute of Biotechnology, Department of Genetics, University of Glasgow, UK
    Nucleic Acids Res 21:2801-8. 1993
    ..in the major replication pause region, at the junction of the genes for ATP synthase subunit 6 and cytochrome c oxidase subunit III (COIII)...
  19. pmc Mitochondrial sequence data expose the putative cosmopolitan polychaete Scoloplos armiger (Annelida, Orbiniidae) as a species complex
    Christoph Bleidorn
    Animal Systematics and Evolution, Institute for Biology, Zoology, Free University Berlin, Koenigin Luise Str, 1 3, D 14195 Berlin, Germany
    BMC Evol Biol 6:47. 2006
    ..armiger mitochondrial genome and developed primers for variable regions including the 3' end of the cox3 gene, trnQ, and most of nad6. A phylogenetic analysis of this 528-nucleotide fragment was carried out for S...
  20. pmc Alternative mRNA editing in trypanosomes is extensive and may contribute to mitochondrial protein diversity
    Torsten Ochsenreiter
    Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA
    PLoS ONE 3:e1566. 2008
    ..Recently, it has been shown that cytochrome c oxidase subunit III (COXIII) mRNAs can be alternatively edited to encode a novel mitochondrial membrane protein composed ..
  21. pmc A novel small-subunit ribosomal protein of yeast mitochondria that interacts functionally with an mRNA-specific translational activator
    T W McMullin
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    Mol Cell Biol 10:4590-5. 1990
    Mitochondrial translation of the mRNA encoding cytochrome c oxidase subunit III (coxIII) specifically requires the action of three position activator proteins encoded in the nucleus of Saccharomyces cerevisiae...
  22. pmc Transfer RNA genes in Drosophila mitochondrial DNA: related 5' flanking sequences and comparisons to mammalian mitochondrial tRNA genes
    D O Clary
    Nucleic Acids Res 11:2411-25. 1983
    ..The tRNAgly gene lies between the genes for cytochrome c oxidase subunit III and URF3, and all three of these genes are contained in the same strand of the mtDNA molecule...
  23. pmc Rpm2, the protein subunit of mitochondrial RNase P in Saccharomyces cerevisiae, also has a role in the translation of mitochondrially encoded subunits of cytochrome c oxidase
    V Stribinskis
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Louisville, Louisville, KY 40292, USA
    Genetics 158:573-85. 2001
    ..Pulse-chase analysis of mitochondrial translation revealed decreased rates of translation of COX1, COX2, and COX3 mRNAs...
  24. ncbi The mitochondrial genome of the thermal dimorphic fungus Penicillium marneffei is more closely related to those of molds than yeasts
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong, PR China
    FEBS Lett 555:469-77. 2003
    ..synthase subunits 6, 8, and 9 (atp6, atp8, and atp9), cytochrome oxidase subunits I, II, and III (cox1, cox2, and cox3), apocytochrome b (cob), reduced nicotinamide adenine dinucleotide ubiquinone oxireductase subunits (nad1, nad2, ..
  25. ncbi RNA editing has been lost in the mitochondrial cox3 and rps13 mRNAs in Asparagales
    L Lopez
    Dipartimento di Biologia Cellulare, Universita della Calabria, Ponte P Bucci, Cubo 4C, 87030 Arcavacata di Rende, Italy
    Biochimie 89:159-67. 2007
    ..for RNA editing in the complete genomic sequences of the gene encoding the cytochrome oxidase subunit III (cox3) and the ribosomal protein S13 (rps13) in 59 closely related species within the Asparagales and Liliales (monocots)...
  26. ncbi Mitochondrial genome of a tertiary endosymbiont retains genes for electron transport proteins
    Behzad Imanian
    Genetics Graduate Program, Department of Botany, University of British Columbia, 3529 6270 University Boulevard, Vancouver, BC, Canada V6T 1Z4
    J Eukaryot Microbiol 54:146-53. 2007
    ..we describe the first mitochondrial genes from this system: cytochrome c oxidase 1 (cox1), cytochrome oxidase 3 (cox3), and cytochrome b (cob)...
  27. ncbi Mitochondrial DNA fragments released through the permeability transition pore correspond to specific gene size
    Noemí García
    Departamento de Bioquimica, Instituto Nacional de Cardiologia, Ignacio Chavez, Juan Badiano 1 Col Sección XVI, México D F 14080, Mexico
    Life Sci 81:1160-6. 2007
    ..through the polymerase chain reaction (PCR), using specific primers for each mitochondrial gene (MTCO1, MTCO2, MTCO3, MTND3, MTND5, MTATP6, MTATP8, and MTCYB)...
  28. doi On the role of character loss in orbiniid phylogeny (Annelida): molecules vs. morphology
    Christoph Bleidorn
    Unit of Evolutionary Biology Systematic Zoology, Institute of Biochemistry and Biology, University of Potsdam, Karl Liebknecht Strasse 24 25, Haus 26, D 14476 Potsdam Golm, Germany
    Mol Phylogenet Evol 52:57-69. 2009
    ..Additionally, we assembled sequence data of six genes (18S, 16S, cox1, cox3, nad1, nad4) for a representative orbiniid taxon sampling and analysed all data in concatenation using Maximum ..
  29. doi The complete mitochondrial genome of the yeast Pichia sorbitophila
    Paul P Jung
    Unité de Génétique Moléculaire, Génomique et Microbiologie, Institut de Botanique, UMR7156, Universite de Strasbourg, Strasbourg, France
    FEMS Yeast Res 9:903-10. 2009
    ..It encodes three subunits of cytochrome oxidase (COX1, COX2 and COX3), three subunits of ATP synthase (ATP6, ATP8 and ATP9), the seven subunits of NADH dehydrogenase (NAD1-6 and NAD4L),..
  30. doi The PPR protein encoded by the LOVASTATIN INSENSITIVE 1 gene is involved in RNA editing at three sites in mitochondria of Arabidopsis thaliana
    Daniil Verbitskiy
    Molekulare Botanik, Universitat Ulm, 89069 Ulm, Germany
    Plant J 61:446-55. 2010
    ..Here we identify the nuclear-encoded gene MEF11, which is involved in RNA editing of the three sites cox3-422, nad4-124 and ccb203-344 in Arabidopsis thaliana...
  31. pmc Analysis of the evolutionary forces shaping mitochondrial genomes of a Neotropical malaria vector complex
    Jaroslaw Krzywinski
    Vector Group, Liverpool School of Tropical Medicine, Liverpool, UK
    Mol Phylogenet Evol 58:469-77. 2011
    ..Six protein coding genes (nad5, nad4, cox3, atp6, cox1 and nad2) have high levels of sequence divergence and are likely informative for population genetics ..
  32. doi The complete mitochondrial genome of Pseudochauhanea macrorchis (Monogenea: Chauhaneidae) revealed a highly repetitive region and a gene rearrangement hot spot in Polyopisthocotylea
    Juan Zhang
    Key Laboratory for Aquatic Products Safety of Ministry of Education State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, 135 Xingang West Road, Haizhu District, Guangzhou 510275, China
    Mol Biol Rep 39:8115-25. 2012
    ..The gene rearrangement hot spot located between the cox3 and nad5 genes, including a cluster of tRNA genes, nad6 gene and one major NCR...
  33. pmc An outbreak of trichinosis with molecular identification of Trichinella sp. in Vietnam
    Nguyen van De
    Department of Parasitology, Hanoi Medical University, Vietnam
    Korean J Parasitol 50:339-43. 2012
    ..larvae in the muscle. The larvae detected in the patients were identified as T. spiralis (Vietnamese strain) by the molecular analysis of the mitochondrial cytochrome c oxidase subunit III (cox3) gene.
  34. doi Variability of the honey bee mite Varroa destructor in Serbia, based on mtDNA analysis
    Bojan Gajic
    Department of Parasitology, Faculty of Veterinary Medicine, University of Belgrade, Bul oslobodjenja 18, 11000 Belgrade, Serbia
    Exp Appl Acarol 61:97-105. 2013
    ..Four fragments within cox1, atp6, cox3 and cytb mtDNA genes were sequenced. The Korea haplotype of V...
  35. doi Complete mitochondrial genome of Zebra tilapia, Tilapia buttikoferi
    Xi Dong Mu
    a Key Laboratory of Tropical and Subtropical Fishery Resource Application and Cultivation, Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Ministry of Agriculture, Guangzhou, China
    Mitochondrial DNA A DNA Mapp Seq Anal 27:44-5. 2016
    ..Seven (ND1, ND2, COX1, ATPase8, ATPase6, ND4L and ND6) used TAA or AGA as the termination codon, whereas six (COX2, COX3, ND3, ND4, ND5 and cyt b) had incomplete stop codon T...
  36. pmc Knockdown of the Rhipicephalus microplus cytochrome c oxidase subunit III gene is associated with a failure of Anaplasma marginale transmission
    Thaís D Bifano
    Department of Parasitology, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo, Sao Paulo, SP, Brazil Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, United States of America
    PLoS ONE 9:e98614. 2014
    ..marginale to naïve calves. To our knowledge, this is the first report demonstrating that RNAi of a tick gene is associated with a failure of A. marginale transmission. ..
  37. doi Complete mitochondrial genome of the Antarctic bullhead notothen, Notothenia coriiceps (Perciformes, Nototheniidae)
    Jae Soon Oh
    a Division of Biotechnology, College of Life Sciences, Korea University, Seoul, Republic of Korea
    Mitochondrial DNA A DNA Mapp Seq Anal 27:1407-8. 2016
    ..Of the thirteen protein-coding genes, two genes (cox1 and atp6) had GTG start codons, and six genes (nad2, cox2, cox3, nad3, nad4, and cytb) had incomplete stop codons that require the post-transcriptional addition of A bases...
  38. doi Repeat region absent in mitochondrial genome of tube-dwelling diatom Berkeleya fennica (Naviculales, Bacillariophyceae)
    Sung Min An
    a Korea Institute of Ocean Science and Technology, Ansan, Republic of Korea
    Mitochondrial DNA A DNA Mapp Seq Anal 27:2137-8. 2016
    ..ATG start codon, except 9 genes such as ATA for rps8; ATC for rps14; ATT for rps12 and orf51; GTG for nad5; TTA for cox3, nad4 and orf147; and TTG for cob. The nad11 and rrs are the only interrupted genes in the mitogenome...
  39. doi Divergent mitochondrial respiratory chains in phototrophic relatives of apicomplexan parasites
    Pavel Flegontov
    Institute of Parasitology, Biology Centre, Czech Academy of Sciences, Ceske Budejovice, Czech Republic Life Science Research Centre, Department of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic
    Mol Biol Evol 32:1115-31. 2015
    ..genome of Chromera has the smallest known protein-coding capacity of all mitochondria, encoding just cox1 and cox3 on heterogeneous linear molecules...
  40. doi The complete mitochondrial genome of the confused flour beetle Tribolium confusum (Coleoptera: Tenebrionidae)
    Jing Ou
    a Co Innovation Center for Qinba Regions Sustainable Development, College of Life Sciences, Shaanxi Normal University, Xi an, P R China
    Mitochondrial DNA A DNA Mapp Seq Anal 27:3297-8. 2016
    ..Ten genes use standard complete termination codon (six TAA, three TAG), whereas the cox2, cox3, nad4 and nad5 genes end with single T...
  41. ncbi The complete mitochondrial genome of the fulvous parrotbill Paradoxornis fulvifrons (Passeriformes: Muscicapidae)
    Longying Wen
    a Sichuan Institute Key Laboratory for Protecting Endangered Birds in the Southwest Mountains, College of Life Sciences, Leshan Normal University, Leshan, Sichuan, China and
    Mitochondrial DNA . 2015
    ..One PCG (COX1) is terminated with AGG, three PCGs (COX3, ND2 and ND4) with the incomplete stop codon T--/TA-, while all the others with TAA...
  42. doi Genetic delineation between and within the widespread coccolithophore morpho-species Emiliania huxleyi and Gephyrocapsa oceanica (Haptophyta)
    El Mahdi Bendif
    CNRS UMR7144 UPMC, EPEP team, Station Biologique de Roscoff, Roscoff, 29682, France
    J Phycol 50:140-8. 2014
    ..Using nuclear (18S rDNA and 28S rDNA), mitochondrial (cox1, cox2, cox3, rpl16, and dam), and plastidial (16S rDNA, rbcL, tufA, and petA) DNA markers from 99 E. huxleyi and 44 G...
  43. pmc Recent Reticulate Evolution in the Ecologically Dominant Lineage of Coccolithophores
    El Mahdi Bendif
    Marine Biological Association of the UK Plymouth, UK
    Front Microbiol 7:784. 2016
    ..by sequencing 5 marker genes (nuclear 18S and 28S rDNA, plastidial tufA, and mitochondrial cox1 and cox3 genes)...
  44. doi Genetic divergence between Mexican Opuntia accessions inferred by polymerase chain reaction-restriction fragment length polymorphism analysis
    S Samah
    Laboratorio de Biologia Molecular, Departamento de Fitotecnia, Universidad Autonoma Chapingo, Texcoco, Mexico
    Genet Mol Res 15:. 2016
    ..and psbA-trnH), one chloroplast gene (ycf1), two nuclear genes (ppc and PhyC), and one mitochondrial gene (cox3) was conducted...
  45. doi Genetic diversity and population structure of Kazakh horses (Equus caballus) inferred from mtDNA sequences
    M Gemingguli
    College of Animal Science, Tarim University, Alar, Xinjiang, China
    Genet Mol Res 15:. 2016
    ..with other horse breeds using the mtDNA D-loop region, Cyt b gene, and a DNA fragment (nps 7974-9963, containing COX3, tRNA-Gly, ND3, and tRNA-Arg)...
  46. doi Genetic variability among Schistosoma japonicum isolates from different endemic regions in China revealed by sequences of three mitochondrial DNA genes
    G H Zhao
    College of Veterinary Medicine, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou, Guangdong Province 510642, PR China
    Vet Parasitol 162:67-74. 2009
    ..examined sequence variation in three mitochondrial DNA (mtDNA) regions, namely cytochrome c oxidase subunit 3 (cox3), NADH dehydrogenase subunits 4 and 5 (nad4 and nad5), among Schistosoma japonicum isolates from different endemic ..
  47. doi Age-dependent down-regulation of mitochondrial 8-oxoguanine DNA glycosylase in SAM-P/8 mouse brain and its effect on brain aging
    Feng Tian
    Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Peking University Research Center on Aging, Beijing, China
    Rejuvenation Res 12:209-15. 2009
    ..and protein levels of OGG1, especially OGG1 targeting to mitochondria, and the expression level of cytochrome c oxidase subunit III (COX III) in the brain of both SAM-P/8 mice and SAM-R/1 mice, decreased with age...
  48. doi Molecular evolution of cytochrome C oxidase underlies high-altitude adaptation in the bar-headed goose
    Graham R Scott
    Department of Zoology, University of British Columbia, Vancouver, BC, Canada
    Mol Biol Evol 28:351-63. 2011
    ..However, the COX3 gene of bar-headed geese contained a nonsynonymous substitution at a site that is otherwise conserved across ..
  49. doi Complete sequence and analysis of the mitochondrial genome of the methylotrophic yeast Hansenula polymorpha DL-1
    Mikhail A Eldarov
    Laboratory of Genetic Engineering, Centre Bioengineering of RAS, Moscow, Russia
    FEMS Yeast Res 11:464-72. 2011
    ..It contains genes for three subunits of cytochrome oxidase (cox1, cox2 and cox3), three subunits of ATP synthase (atp6, atp8 and atp9), seven subunits of NADH dehydrogenase (nad1-6 and nad4L), ..
  50. doi Mitochondrial DNA mutations and polymorphisms in asthenospermic infertile men
    Siwar Baklouti-Gargouri
    Laboratory of Molecular Human Genetics, Sfax Faculty of Medicine, University of Sfax, Avenue Majida Boulila, 3029, Sfax, Tunisia
    Mol Biol Rep 40:4705-12. 2013
    ..225 to +1.100) and a decrease of the protein 3D structures number (from 39 to 32) as shown by PolyPhen bioinformatic program...
  51. doi The complete mitochondrial genome sequence of Hepatozoon catesbianae (Apicomplexa: Coccidia: Adeleorina), a blood parasite of the green frog, Lithobates (formerly Rana) clamitans
    Alexandre N Leveille
    Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, N1G 2W1 Canada
    J Parasitol 100:651-6. 2014
    ..is 6,397 bp in length and contains 3 protein-coding genes (cytochrome c oxidase subunit I [COI]; cytochrome c oxidase subunit III [COIII]; and cytochrome B [CytB])...
  52. pmc Aim-less translation: loss of Saccharomyces cerevisiae mitochondrial translation initiation factor mIF3/Aim23 leads to unbalanced protein synthesis
    Anton Kuzmenko
    University of Tartu, Institute of Technology, Nooruse 1, 50411 Tartu, Estonia
    Sci Rep 6:18749. 2016
    ..of synthesis of the Atp9 subunit of F1F0 ATP synthase (complex V) is increased, while expression of Cox1, Cox2 and Cox3 subunits of cytochrome c oxidase (complex IV) is repressed...
  53. doi Toward an inordinate fondness for stars, beetles and Lobophora? Species diversity of the genus Lobophora (Dictyotales, Phaeophyceae) in New Caledonia
    Christophe Vieira
    CoReUs, LABEX CORAIL, U227 Biocomplexité des écosystèmes coralliens, Institut de Recherche pour le Developpement, B P A5, 98848 Noumea Cedex, Nouvelle Calédonie, France
    J Phycol 50:1101-19. 2014
    ..were delineated using general mixed Yule coalescent-based and barcoding gap approaches applied to a mitochondrial cox3 data set. Results were subsequently confirmed using chloroplast psbA and rbcL data sets...
  54. doi Light induces translocation of NF-κB p65 to the mitochondria and suppresses expression of cytochrome c oxidase subunit III (COX III) in the rat retina
    Hiroshi Tomita
    Laboratory of Visual Neuroscience, Graduate Course in Biological Sciences, Iwate University Division of Science and Engineering, 4 3 5 Ueda, Morioka, Iwate 020 8551, Japan Soft Path Engineering Research Center SPERC, Faculty of Science and Engineering, Iwate University, Morioka 020 8551, Japan Clinical Research, Innovation and Education Center, Tohoku University Hospital, 1 1 Seiryo, Aoba, Sendai, Miyagi 980 8574, Japan Electronic address
    Biochem Biophys Res Commun 473:1013-8. 2016
    ..retinal NF-κB translocates to the mitochondria, an event associated with a decrease in expression of cytochrome c oxidase subunit III (COX III)...
  55. pmc Mitochondrial Genetic Variation in Iranian Infertile Men with Varicocele
    Mohammad Mehdi Heidari
    Department of Biology, Faculty of Science, Yazd University, Yazd, Iran
    Int J Fertil Steril 10:303-309. 2016
    ..aim of this study was to scan nine mitochondrial genes (MT-COX2, MT-tRNALys , MT-ATP8, MT-ATP6, MT-COX3, MT-tRNAGly , MT-ND3, MT-tRNAArg and MT-ND4L) for mutations in infertile patients ..
  56. pmc Disruption of the yeast nuclear PET54 gene blocks excision of mitochondrial intron aI5 beta from pre-mRNA for cytochrome c oxidase subunit I
    M L Valencik
    Department of Microbiology, University of California, Los Angeles 90024
    EMBO J 8:3899-904. 1989
    ..two mitochondrial genes: COX1, which encodes cytochrome c oxidase subunit I, and COX3, which encodes cytochrome c oxidase subunit III. The defect in COX1 gene expression in the pet54 mutant was shown to be the result of inefficient ..
  57. ncbi COX3 mRNA-specific translational activator proteins are associated with the inner mitochondrial membrane in Saccharomyces cerevisiae
    T W McMullin
    Section of Genetics and Development, Cornell University, Ithaca, New York 14853 2703
    J Biol Chem 268:11737-41. 1993
    ..genes, PET54, PET122, and PET494, are specifically required to activate translation of the mitochondrially coded COX3 mRNA, and one of them, PET122, has been shown to interact functionally with both the mitochondrial ribosomal small ..
  58. pmc Highly diverged homologs of Saccharomyces cerevisiae mitochondrial mRNA-specific translational activators have orthologous functions in other budding yeasts
    M C Costanzo
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853 2703, USA
    Genetics 154:999-1012. 2000
    ..We searched unsuccessfully in divergent budding yeasts for orthologs of the COX2- and COX3-specific translational activator genes, PET111, PET54, PET122, and PET494, by direct complementation...
  59. ncbi Isolation and characterization of cytochrome c from the marine copepod Tigriopus californicus
    P D Rawson
    Marine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, USA
    Gene 248:15-22. 2000
    ..by the nuclear CYC gene) and cytochrome c oxidase (partly encoded in the mitochondrial DNA by the COX1, COX2 and COX3 genes)...
  60. ncbi Structure of nuclear-localized cox3 genes in Chlamydomonas reinhardtii and in its colorless close relative Polytomella sp
    Xochitl Perez-Martinez
    Departamento de Genetica Molecular, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, Apartado Postal 70 243, 04510, D F, Mexico
    Curr Genet 40:399-404. 2002
    Several chlorophyte algae do not have the cox3 gene, encoding subunit III of cytochrome c oxidase, in their mitochondrial genomes...
  61. ncbi Rsf1p, a protein required for respiratory growth of Saccharomyces cerevisiae
    Lin Lu
    Department of Immunology and Microbiology, Wayne State University School of Medicine, Gordon H Scott Hall, 540 East Canfield Avenue, Detroit, MI 48201, USA
    Curr Genet 43:263-72. 2003
    ..sequence (UAS) in its 5'-flanking region, are attenuated in the DeltaYMR030 W mutant, but mRNA from the mt COX3 ( OXI2) gene, which lacks the mt UAS, are not...
  62. ncbi Somatic mitochondrial DNA mutations in oral cancer of betel quid chewers
    Duan Jun Tan
    Institute for Molecular and Human Genetics, Georgetown University Medical Center, Washington, DC 20007, USA
    Ann N Y Acad Sci 1011:310-6. 2004
    ..One frameshift mutation, 9485delC, was in cytochrome c oxidase subunit III. Eight (44%) tumors had insertion or deletion mutations in the np303-309 poly C region of the D-loop...
  63. ncbi Downregulation of ATP synthase subunit-6, cytochrome c oxidase-III, and NADH dehydrogenase-3 by bright cyclic light in the rat retina
    Hu Huang
    Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, 73104, USA
    Invest Ophthalmol Vis Sci 45:2489-96. 2004
    ..In this study, the objective was to study the mechanisms of neuroprotection in the bright cyclic light-reared retina by identification of differentially expressed genes with differential display (DD)-PCR...
  64. ncbi [Editing of the mitochondrial cox3 transcript may yield a new site of protein-protein interactions in wild cereal Elymus sibiricus L]
    E L Tauson
    Mol Biol (Mosk) 38:420-8. 2004
    ..nucleotide sequences were established for the Elymus sibiricus mitochondrial cytochrome c oxidase subunit 3 gene (cox3) and its cDNA...
  65. ncbi RNA interference analyses suggest a transcript-specific regulatory role for mitochondrial RNA-binding proteins MRP1 and MRP2 in RNA editing and other RNA processing in Trypanosoma brucei
    Eva Vondrusková
    Institute of Parasitology, Czech Academy of Sciences, and Faculty of Biology, University of South Bohemia, 37005 Ceske Budejovice, Czech Republic
    J Biol Chem 280:2429-38. 2005
    ..substantially reduced levels of edited CyB and RPS12 mRNAs but little or no reduction of the level of edited Cox2, Cox3, and A6 mRNAs as measured by poisoned primer extension analyses...
  66. ncbi Plasma membrane oxidoreductase activity in cultured cells in relation to mitochondrial function and oxidative stress
    Giulia Deleonardi
    Dipartimento di Biochimica, Universita di Bologna, Via Irnerio 48, 40126 Bologna, Italy
    Biofactors 20:251-8. 2004
    ..with platelets from a patient with a nucleotide 9957 mutation in mitochondrial DNA (encoding for cytochrome c oxidase subunit III) in comparison with the parent 143B line...
  67. ncbi Expression of green fluorescent protein from a recoded gene inserted into Saccharomyces cerevisiae mitochondrial DNA
    J S Cohen
    Department of Molecular Medicine, Cornell University, Ithaca, NY 14853 2703, USA
    Mitochondrion 1:181-9. 2001
    ..This reporter gene, GFP(m)-3, was inserted into mtDNA at the eighth codon of the COX3 gene. Mitochondria containing this mtDNA could be detected by fluorescence microscopy...
  68. ncbi The complete DNA sequence of the mitochondrial genome of the dermatophyte fungus Epidermophyton floccosum
    José Humberto M Tambor
    Instituto de Ciencias Biomedicas, Departamento de Microbiologia, Universidade de Sao Paulo, Av Prof Lineu Prestes, 1374, Ed Biomédicas II, Cidade Universitaria, CEP 05508 900, Sao Paulo, Brazil
    Curr Genet 49:302-8. 2006
    ..oxireductase (nad1, nad2, nad3, nad4, nad4L, nad5, and nad6), three subunits of cytochrome oxidase (cox1, cox2, and cox3), apocytochrome b (cob), three subunits of ATP synthase (atp6, atp8, and atp9), the small and large ribosomal RNAs (..
  69. ncbi Differential expression of cytochrome c oxidase subunit III gene in castes of the termite Reticulitermes santonensis
    Marjorie A Liénard
    Department of Ecology, Lund University, Solvegatan 37, SE 223 62 Lund, Sweden
    J Insect Physiol 52:551-7. 2006
    ..We used the cytochrome c oxidase subunit III gene (COXIII) that was cloned from mRNA in a lower termite, Reticulitermes santonensis De Feytaud (..
  70. ncbi Extensive variation in nuclear mitochondrial DNA content between the genomes of Phytophthora sojae and Phytophthora ramorum
    Konstantinos Krampis
    Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061 0477, USA
    Mol Plant Microbe Interact 19:1329-36. 2006
    ..ramorum NUMTs most often originate from the cox3, rpsl4, nad4, and nad5 genes...
  71. ncbi Organization of the mitochondrial genome in the dinoflagellate Amphidinium carterae
    Edmund A Nash
    Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom
    Mol Biol Evol 24:1528-36. 2007
    ..It contains just 3 identifiable protein-coding genes: cox1, cox3, and cob. No evidence for rRNA or tRNA genes was found...
  72. ncbi Deletion of the MTO2 gene related to tRNA modification causes a failure in mitochondrial RNA metabolism in the yeast Saccharomyces cerevisiae
    Xinjian Wang
    Division of Human Genetics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    FEBS Lett 581:4228-34. 2007
    ..Furthermore, the steady-state levels of mitochondrial mRNA CYTB, COX1, COX2, COX3, and ATP6 were markedly decreased in mto2 strains...
  73. ncbi Screening of phage displayed human liver cDNA library against dexamethasone
    Xiaoming Yu
    National Chromatographic Research and Analysis Center, Dalian Institute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116023, PR China
    J Pharm Biomed Anal 45:701-5. 2007
    ..phages with the lengths of 400 and 600 bp were sequenced, and revealed identical sequences with cytochrome c oxidase subunit III and albumin respectively by GenBank searching...
  74. doi Mitochondrial genome polymorphisms associated with longissimus muscle composition in Iberian pigs
    A I Fernandez
    Departamento de Mejora Genética Animal, INIA, Ctra de La Coruña Km 7 5, 28040 Madrid, Spain
    J Anim Sci 86:1283-90. 2008
    ..detected in H3 carriers: a synonymous transition 9104C > T in the gene-coding region of Cytochrome c oxidase subunit III and a substitution 715A > G in 12S rRNA...
  75. doi Identification of differentially expressed genes in the growth plate of broiler chickens with thiram-induced tibial dyschondroplasia
    W X Tian
    State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
    Avian Pathol 38:161-6. 2009
    ..pro-alpha-1 collagen type I (Col I alpha1), collagen type IX (Col IX), NADH dehydrogenase (NADH DH), cytochrome C oxidase subunit III (COX III), enolase 1, alpha (ENO1), carbonic anhydrase II (CA2) and heat shock protein 90 (Hsp90) ..
  76. doi Long-term cycles of hypoxia and normoxia increase the contents of liver mitochondrial DNA in rats
    Yongjun Luo
    Department of High Altitude Diseases, Third Military Medical University, Chongqing 400038, People s Republic of China
    Eur J Appl Physiol 113:223-32. 2013
    ..the contents of liver mtDNA, mitochondrial transcription factor A (mtTFA), cytochrome oxidase 1 (COX1), COX2, and COX3 mRNA transcripts, and mitochondrial respiratory activity were examined immediately after the last cycle...
  77. doi Burst of succinate dehydrogenase and α-ketoglutarate dehydrogenase activity in concert with the expression of genes coding for respiratory chain proteins underlies short-term beneficial physiological stress in mitochondria
    Marina V Zakharchenko
    Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia
    Int J Biochem Cell Biol 45:190-200. 2013
    ..The burst of ROS formation was congruous with changes in SDH and KDH activity, as well as in ucp2 and cox3 expression, while the activity of SDH was inversely dependent on the expression of the gene of its catalytic ..
  78. doi Complete mitochondrial genome of the ring-necked pheasant, Phasianus colchicus (Galliformes: Phasianidae)
    Xifeng Li
    The Provincial Key Laboratory of Conservation and Exploitation Research of Biological Resources in Anhui, Wuhu 241000, Republic of China
    Mitochondrial DNA 24:89-90. 2013
    ..All protein-coding, rRNA, and tRNA genes have more than 99.0% nucleotide sequence similarity with the previously reported individual, except for cox3 and tRNA (Pro) genes which has more similarity with Phasianus versicolor.
  79. doi Whole genomic sequencing of RT98 mitochondria derived from Oryza rufipogon and northern blot analysis to uncover a cytoplasmic male sterility-associated gene
    Keisuke Igarashi
    Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
    Plant Cell Physiol 54:237-43. 2013
    ..The orf113 gene was shown to be co-transcribed with atp4 and cox3 encoding ATP synthase F0 subunit 4 and Cyt c oxidase subunit 3, respectively, and their transcripts were distinctly ..
  80. pmc Identification of a novel m.9588G > a missense mutation in the mitochondrial COIII gene in asthenozoospermic Tunisian infertile men
    Siwar Baklouti-Gargouri
    Laboratory of Molecular Human Genetics, Sfax Faculty of Medicine, University of Sfax, Avenue Majida Boulila, 3029, Sfax, Tunisia
    J Assist Reprod Genet 31:595-600. 2014
    ..It has been demonstrated that mtDNA base substitutions can greatly influence semen quality...
  81. doi Complete mitochondrial genome of a Light-vented Bulbul subspecies, Pycnonotus sinensis hainanus (Passeriformes: Pycnonotidae)
    Qiongqiong Ren
    a The Provincial Key Laboratory of the Conservation and Exploitation Research of Biological Resources in Anhui, Wuhu, People s Republic of China
    Mitochondrial DNA A DNA Mapp Seq Anal 27:375-7. 2016
    ..0% nucleotide sequence similarity with the previously reported individual of P. s. formosae, except for cox3 and CRs. Notably, we found that the nucleotide sequence of P. s. formosae mtDNA has more similarity with P...
  82. doi Characterization of the complete mitochondrial genome of Collared Finchbill, Spizixos semitorques (Passeriformes: Pycnonotidae)
    Qiongqiong Ren
    a The Provincial Key Laboratory of the Conservation and Exploitation Research of Biological Resources in Anhui, Wuhu, People s Republic of China and
    Mitochondrial DNA A DNA Mapp Seq Anal 27:700-2. 2016
    ..are found in seven protein-coding genes, while AGA for nad1 and nad5, AGG for cox1, and the remaining genes (nad2, cox3, nad4) have incomplete termination codons (TA- or T- -). All tRNA genes have a typical clover-leaf structure...
  83. doi Parallel evolution of cox genes in H2S-tolerant fish as key adaptation to a toxic environment
    Markus Pfenninger
    Molecular Ecology Group, Biodiversity and Climate Research Centre by Senckenberg Naturforschende Gesellschaft and Goethe Universität, 60325 Frankfurt, Germany
    Nat Commun 5:3873. 2014
    ..of COX evolved in parallel in two sulphide lineages, as evidenced by shared amino acid substitutions in cox1 and cox3 genes. One of the shared substitutions likely triggers conformational changes in COX1 blocking the access of H2S...
  84. doi Complete mitochondrial genome of the hybrid of Oreochromis niloticus (♀) × Oreochromis aureus (♂)
    Xin Zhu
    a College of Veterinary Medicine, Hunan Agriculture University, Changsha, Hunan, P R China and
    Mitochondrial DNA A DNA Mapp Seq Anal 27:1777-8. 2016
    ..Eight genes end with the complete stop codon TAA or TAG, while the COX2, COX3, ND3, ND4 and Cytb genes terminated with an incomplete stop codon T...
  85. ncbi Characterization of the complete mitochondrial genome of Bombyx huttoni (Lepidoptera: Bombycidae)
    Xiao Yi Peng
    a Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest China, College of Life Sciences, Shaanxi Normal University, Xi an, PR China
    Mitochondrial DNA A DNA Mapp Seq Anal 27:4112-4113. 2016
    ..Twelve PCGs (COX2, COX3, CYTB, ND1, ND2, ND3, ND4, ND4L, ND5, ND6, ATP6, and ATP) are initiated with the typical ATN codons, whereas COX1 ..
  86. pmc Characterization and phylogenetic analysis of the mitochondrial genome of Shiraia bambusicola reveals special features in the order of pleosporales
    Xiao ye Shen
    College of Life Science, Capital Normal University, Beijing, People s Republic of China
    PLoS ONE 10:e0116466. 2015
    ..regions of gene orders partitioned in their mitochondrial genomes, including block 1 (nad6-atp6), block 2 (nad1-cox3) and block 3 (genes around rns). S...
  87. doi Morphological and Phylogenetic Characterization of New Gephyrocapsa Isolates Suggests Introgressive Hybridization in the Emiliania/Gephyrocapsa Complex (Haptophyta)
    El Mahdi Bendif
    Marine Biological Association of the UK, Plymouth, UK Electronic address
    Protist 166:323-36. 2015
    ..and phylogenetic analysis of 6 genes (nuclear 18S and 28S rDNA, plastidial 16S and tufA, and mitochondrial cox1 and cox3 genes). Morphometric features of the coccoliths indicate that these isolates are distinct from G...
  88. pmc Adaptation of the Mitochondrial Genome in Cephalopods: Enhancing Proton Translocation Channels and the Subunit Interactions
    Daniela Almeida
    CIIMAR CIMAR, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Porto, Portugal Department of Biology, Faculty of Sciences, University of Porto, Porto, Portugal
    PLoS ONE 10:e0135405. 2015
    ..in the energy production pathway of cephalopods: ND5 and ND6 from Complex I, CYTB from Complex III, COX2 and COX3 from Complex IV, and in ATP8 from Complex V...
  89. ncbi Sequence characterization and phylogeny analysis of the complete mitochondrial genome of verreaux's sifaka, Propithecus verreauxi (primates: indriidae)
    Hongmei Yao
    a Department of Gynecology, Affiliated Hospital of Jining Medical University, Jining, China
    Mitochondrial DNA A DNA Mapp Seq Anal 27:4431-4432. 2016
    ..With the exception of COX3, which terminates with an incomplete stop codon (T-), all the other PCGs initiates with a traditional ATN start ..
  90. ncbi The complete mitochondrial genome of the black star fat minnow (Rhynchocypris semotilus), an endemic and endangered fish of Korea
    Jeong Nam Yu
    a National Institute of Biological Resources, Environmental Research Complex, Incheon, Korea
    Mitochondrial DNA . 2015
    ..semotilus were similar to that of most other vertebrates. Four overlapping regions in ATP8/ATP6, ATP6/COX3, ND4L/ND4, and ND5/ND6, among the 13 PCGs were found...
  91. doi Occurrence of Deformed wing virus, Chronic bee paralysis virus and mtDNA variants in haplotype K of Varroa destructor mites in Syrian apiaries
    Toufic Elbeaino
    CIHEAM Istituto Agronomico Mediterraneo, Via Ceglie 9, 70010, Valenzano, BA, Italy
    Exp Appl Acarol 69:11-9. 2016
    ..analyzed by amplifying and sequencing four fragments in cytochrome oxidase subunit 1 (cox1), ATP synthase 6 (atp6), cox3 and cytochrome b (cytb) mitochondrial DNA (mtDNA) genes. Sequences of concatenated V...
  92. pmc Dynamic gene expression profiles during postnatal development of porcine subcutaneous adipose
    Jie Zhang
    Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Sichuan Agricultural University, Ya an, Sichuan, China Department of Animal Science, Southwest University at Rongchang, Chongqing, China
    Peerj 4:e1768. 2016
    ..A set of universally abundant genes (ATP8, COX2, COX3, ND1, ND2, SCD and TUBA1B) was found across all four developmental stages...
  93. doi A MORPHOLOGICAL AND MOLECULAR STUDY OF AUSTRAL SARGASSUM (FUCALES, PHAEOPHYCEAE) SUPPORTS THE RECOGNITION OF PHYLLOTRICHA AT GENUS LEVEL, WITH FURTHER ADDITIONS TO THE GENUS SARGASSOPSIS(1)
    Rainbo R M Dixon
    School of Biological Sciences and Biotechnology, Murdoch University, Murdoch, WA 6150, AustraliaSchool of Biological Sciences and Biotechnology, Murdoch University, Murdoch, WA 6150, Australia WA Herbarium, Science Division, Department of Environment and Conservation, Locked Bag 104, Bentley Delivery Centre, WA 6983, AustraliaSchool of Biological Sciences, Victoria University of New Zealand, P O Box 600, Wellington, New ZealandSchool of Earth and Environmental Science, The University of Adelaide, Adelaide, SA 5005, Australia State Herbarium of South Australia, Plant Biodiversity Centre, Hackney Road, G P O Box 1047, Adelaide, SA 5001, Australia South Australian Research and Development Institute, Aquatic Sciences, P O Box 120, Henley Beach, SA 5022, AustraliaSchool of Biological Sciences and Biotechnology, Murdoch University, Murdoch, WA 6150, Australia
    J Phycol 48:1119-29. 2012
    ..the New Zealand endemic Carpophyllum Greville, using morphological evidence and the molecular phylogenetic markers cox3, ITS-2 and the rbcL-S spacer...
  94. pmc Analysis of the Mitochondrial Genome in Hypomyces aurantius Reveals a Novel Twintron Complex in Fungi
    Youjin Deng
    Mycological Research Center, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China
    Int J Mol Sci 17:. 2016
    ..introns were detected in six conserved genes: five in cox1, four in rnl, three in cob, two each in atp6 and cox3, and one in cox2...
  95. pmc Complete Mitochondrial Genome of the Citrus Spiny Whitefly Aleurocanthus spiniferus (Quaintance) (Hemiptera: Aleyrodidae): Implications for the Phylogeny of Whiteflies
    Zhi Teng Chen
    School of Horticulture Plant Protection and Institute of Applied Entomology, Yangzhou University, Yangzhou, 225009, China
    PLoS ONE 11:e0161385. 2016
    ..spiniferus mitogenome had a large degree of rearrangement due to translocation of the nad3-trnG-cox3 gene cluster...
  96. pmc Biology of the Marine Heterotrophic Dinoflagellate Oxyrrhis marina: Current Status and Future Directions
    Zhiling Guo
    Key Laboratory of Tropical Marine Bio resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Science, Guangzhou 510301, China
    Microorganisms 1:33-57. 2013
    ..g., a single histone-like DNA-associated protein, cob-cox3 gene fusion, 5' oligo-U cap in the mitochondrial transcripts of protein-coding genes, the absence of mRNA ..
  97. doi Complete mitochondrial genome of parasitic nematode Cylicocyclus nassatus and comparative analyses with Cylicocyclus insigne
    Yuan Gao
    College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, PR China Electronic address
    Exp Parasitol 172:18-22. 2016
    ..8-6.6%) levels. The nucleotide lengths of the 12 protein-coding genes were the same, except for cox3 which was longer in C. insigne...
  98. doi Genetic variability in the three mitochondrial genes among Oesophagostomum asperum isolates from different regions in Shaanxi and Hunan Provinces, China
    Yan Qing Jia
    College of Veterinary Medicine, Northwest A and F University, Yangling, Shaanxi Province 712100, People s Republic of China
    Mitochondrial DNA 25:298-302. 2014
    ..NADH dehydrogenase subunit 5 (nad5), adenosine triphosphate subunit 6 (atp6) and cytochrome c oxidase subunit 3 (cox3), among Oesophagostomum asperum isolates from different regions in Shaanxi and Hunan provinces, China...
  99. pmc Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV
    Rui Huang
    Beijing Institute of Radiation Medicine, Beijing, China State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Radiation Medicine, Beijing, China
    PLoS ONE 9:e96246. 2014
    ..Furthermore, we found that the level of the complex IV core subunit COX3 and mitochondrial transport-related proteins Tim9 and Tim10 were decreased during the differentiation of K562 cells ..
  100. pmc A peptide fragment from the human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune response
    Sachin Kumar Samuchiwal
    Recombinant Gene Products Group, International Centre for Genetic Engineering and Biotechnology, ICGEB, Aruna Asaf Ali Marg, New Delhi 110067, India
    BMC Infect Dis 14:355. 2014
    ..The disruption of crucial protein-protein interactions, especially those that are responsible for virulence in Mycobacterium tuberculosis - for example the ESAT-6:CFP10 complex - are a worthy pursuit in this direction...
  101. pmc Antagonistic signals within the COX2 mRNA coding sequence control its translation in Saccharomyces cerevisiae mitochondria
    Elizabeth H Williams
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853 2703, USA
    RNA 9:419-31. 2003
    ..leader sequences, as they are also observed when the same reporter constructs are expressed from the COX3 locus...

Research Grants5

  1. The Hig1 protein family and the cytochrome c oxidase complex
    Rosemary A Stuart; Fiscal Year: 2012
    ..Moreover, we demonstrate that Hig1 proteins physically interact with subunit 3 (Cox3) prior to and following its assembly into the COX complex...
  2. Protein-Facilitated Group I Intron Splicing
    Mark Caprara; Fiscal Year: 2006
    ..A co-crystal of IAniI and its DNA target site diffracts to high resolution and the resulting structure will provide a powerful reference to establish structure-function relationships. ..
  3. Mechanism of tRNA Import Into Trypanosome Mitochondria
    STEPHEN HAJDUK; Fiscal Year: 2009
    ..In addition, mitochondrial tRNA import may have therapeutic potential since, in contrast to trypanosomes, all mammalian mitochondrial tRNAs are encoded by mitochondrial genes. ..
  4. Function of mRNA Editing in Trypanosomes
    Stephen L Hajduk; Fiscal Year: 2010
    ..Our initial studies focused on the mRNA for cytochrome c oxidase III (COIII), which we discovered was alternatively edited in Trypanosoma brucei...
  5. The Impact of HLA in Children Receiving HAART
    Akihiko Saitoh; Fiscal Year: 2008
    ..This research will also suggest modes of pathogenesis that can lead to the development of vaccine strategies. ..