COLQ

Summary

Gene Symbol: COLQ
Description: collagen like tail subunit of asymmetric acetylcholinesterase
Alias: CMS5, EAD, acetylcholinesterase collagenic tail peptide, AChE Q subunit, acetylcholinesterase-associated collagen, collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase, collagenic tail of endplate acetylcholinesterase, single strand of homotrimeric collagen-like tail subunit of asymmetric acetylcholinesterase
Species: human

Top Publications

  1. ncbi [Epidemiological studies on enteric adenovirus gastroenteritis in children]
    Y Yamashita
    Ehime Prefectural Institute of Public Health
    Kansenshogaku Zasshi 69:377-82. 1995
  2. pmc Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail subunit (ColQ) of the asymmetric enzyme
    K Ohno
    Department of Neurology and Neuromuscular Research Laboratory, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Proc Natl Acad Sci U S A 95:9654-9. 1998
  3. pmc Mutation in the human acetylcholinesterase-associated collagen gene, COLQ, is responsible for congenital myasthenic syndrome with end-plate acetylcholinesterase deficiency (Type Ic)
    C Donger
    INSERM U153, Group Hospitalier Pitie Salpetriere, France
    Am J Hum Genet 63:967-75. 1998
  4. ncbi [Enzyme-linked immunosorbent assay using monoclonal antibodies for direct serotyping of enteric adenoviruses in feces]
    K Takagi
    Department of Microbiology, Ehime Prefectural Institute of Public Health
    Kansenshogaku Zasshi 65:552-8. 1991
  5. ncbi Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion
    Shelley Camp
    University of California, San Diego, 9500 Gilman Dr, Department of Pharmacology, La Jolla, CA 92093 0636, USA
    Chem Biol Interact 157:79-86. 2005
  6. ncbi The C-terminal peptides of acetylcholinesterase: cellular trafficking, oligomerization and functional anchoring
    Jean Massoulié
    Laboratoire de Neurobiologie Cellulaire et Moleculaire, CNRS UMR 8544, Ecole Normale Superieure, 46 rue d Ulm, 75005 Paris, France
    Chem Biol Interact 157:3-14. 2005
  7. ncbi Early afterdepolarizations and arrhythmogenesis. Experimental and clinical aspects
    N El-Sherif
    Cardiology Division, State University of New York Health Science Center, Brooklyn 11203
    Arch Mal Coeur Vaiss 84:227-34. 1991
  8. doi Reciprocal neural regulation of extrajunctional acetylcholinesterase and collagen Q in rat muscles--the role of calcineurin signaling
    Miha Trinkaus
    Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloska 4, 1000 Ljubljana, Slovenia
    Chem Biol Interact 175:45-9. 2008
  9. ncbi Olfactory responses of Ips duplicatus from inner Mongolia, China to nonhost leaf and bark volatiles
    Q H Zhang
    Department of Crop Science, Swedish University of Agricultural Sciences, Alnarp
    J Chem Ecol 27:995-1009. 2001
  10. ncbi Remodeling of the neuromuscular junction in mice with deleted exons 5 and 6 of acetylcholinesterase
    Emmanuelle Girard
    Laboratoire de Neurobiologie Cellulaire et Moleculaire, UPR 9040, CNRS, 91198 Gif sur Yvette Cedex, France
    J Mol Neurosci 30:99-100. 2006

Research Grants

  1. RICARDO ANIBAL MASELLI; Fiscal Year: 2014
  2. Lai Hua Xie; Fiscal Year: 2015
  3. LAURA ANNE JACOX; Fiscal Year: 2015
  4. Sanda Despa; Fiscal Year: 2015
  5. The role of dynamic changes in repolarization and calcium transients in Long QT r
    Bum Rak Choi; Fiscal Year: 2013
  6. Gideon Koren; Fiscal Year: 2016
  7. Modeling of Cardiac Calcium Dynamics;Ryanodine Receptor induced Arrhythmias
    Daisuke Sato; Fiscal Year: 2013
  8. ROLE OF PROLONGED REPOLARIZATION IN CARDIAC ARRHYTHMIAS
    Dan Roden; Fiscal Year: 1992
  9. MECHANISMS OF CARDIOTOXICITY OF ANTIPSYCHOTIC DRUGS
    David Flockhart; Fiscal Year: 2001
  10. Mechanisms for SIV evasion of vaccine immunity: Role of FasL-mediated cell death
    CHARLES PAUZA; Fiscal Year: 2009

Detail Information

Publications203 found, 100 shown here

  1. ncbi [Epidemiological studies on enteric adenovirus gastroenteritis in children]
    Y Yamashita
    Ehime Prefectural Institute of Public Health
    Kansenshogaku Zasshi 69:377-82. 1995
    Enteric adenoviruses (EAd), adenovirus (Ad) types 40 and 41, have been established as causative agents of gastroenteritis...
  2. pmc Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail subunit (ColQ) of the asymmetric enzyme
    K Ohno
    Department of Neurology and Neuromuscular Research Laboratory, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Proc Natl Acad Sci U S A 95:9654-9. 1998
    ..ACHET) and heteromeric asymmetric forms composed of 1, 2, or 3 tetrameric ACHET attached to a collagenic tail (ColQ). Asymmetric AChE is concentrated at the endplate (EP), where its collagenic tail anchors it into the basal lamina...
  3. pmc Mutation in the human acetylcholinesterase-associated collagen gene, COLQ, is responsible for congenital myasthenic syndrome with end-plate acetylcholinesterase deficiency (Type Ic)
    C Donger
    INSERM U153, Group Hospitalier Pitie Salpetriere, France
    Am J Hum Genet 63:967-75. 1998
    ..which is normally concentrated at NMJs, is composed of catalytic tetramers associated with a specific collagen, COLQ. In CMS-Ic patients, these collagen-tailed forms are often absent...
  4. ncbi [Enzyme-linked immunosorbent assay using monoclonal antibodies for direct serotyping of enteric adenoviruses in feces]
    K Takagi
    Department of Microbiology, Ehime Prefectural Institute of Public Health
    Kansenshogaku Zasshi 65:552-8. 1991
    ..For identification of enteric adenoviruses (EAd) in stool specimens, enzyme-linked immunosorbent assay (ELISA) test using monoclonal antibodies was developed...
  5. ncbi Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion
    Shelley Camp
    University of California, San Diego, 9500 Gilman Dr, Department of Pharmacology, La Jolla, CA 92093 0636, USA
    Chem Biol Interact 157:79-86. 2005
    ..system, whereas the splice to exon 6 produces a sequence that binds to the structural subunits PRiMA and ColQ, producing AChE expression in brain and muscle...
  6. ncbi The C-terminal peptides of acetylcholinesterase: cellular trafficking, oligomerization and functional anchoring
    Jean Massoulié
    Laboratoire de Neurobiologie Cellulaire et Moleculaire, CNRS UMR 8544, Ecole Normale Superieure, 46 rue d Ulm, 75005 Paris, France
    Chem Biol Interact 157:3-14. 2005
    ..wide variety of oligomeric forms, ranging from monomers to heteromeric assemblies containing the anchoring proteins ColQ (collagen-tailed forms) and PRiMA (membrane-bound tetramers), which constitute the major functional enzyme species ..
  7. ncbi Early afterdepolarizations and arrhythmogenesis. Experimental and clinical aspects
    N El-Sherif
    Cardiology Division, State University of New York Health Science Center, Brooklyn 11203
    Arch Mal Coeur Vaiss 84:227-34. 1991
    There is growing evidence that early afterdepolarizations (EADs) and EAD-induced triggered activity play a significant role in the clinical syndrome of long QTU and polymorphic ventricular tachyarrhythmias better known as Torsade de ..
  8. doi Reciprocal neural regulation of extrajunctional acetylcholinesterase and collagen Q in rat muscles--the role of calcineurin signaling
    Miha Trinkaus
    Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloska 4, 1000 Ljubljana, Slovenia
    Chem Biol Interact 175:45-9. 2008
    ..The latter is due to the absence of the expression of AChE-associated collagen Q (ColQ) in the extrajunctional regions of fast muscle fibers, in contrast to its ample expression in slow muscles...
  9. ncbi Olfactory responses of Ips duplicatus from inner Mongolia, China to nonhost leaf and bark volatiles
    Q H Zhang
    Department of Crop Science, Swedish University of Agricultural Sciences, Alnarp
    J Chem Ecol 27:995-1009. 2001
    ..nonhost angiosperm trees were tested on Ips duplicatus by gas chromatographic-electroantennographic detection (GC-EAD) and by pheromone-baited traps in Sweden and Inner Mongolia, China, respectively...
  10. ncbi Remodeling of the neuromuscular junction in mice with deleted exons 5 and 6 of acetylcholinesterase
    Emmanuelle Girard
    Laboratoire de Neurobiologie Cellulaire et Moleculaire, UPR 9040, CNRS, 91198 Gif sur Yvette Cedex, France
    J Mol Neurosci 30:99-100. 2006
    ..homomeric oligomers (monomers, dimers, tetramers), as well as hetero-oligomeric assemblies with anchoring proteins ColQ (Krejci et al., 1997) and PRiMA (Perrier et al., 2002)...
  11. doi Behavioral and electrophysiological responses of Triatoma brasiliensis males to volatiles produced in the metasternal glands of females
    Ana C R Vitta
    Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas, Centro de Pesquisas Rene Rachou Fiocruz, 30 190 002, Belo Horizonte, Minas Gerais, Brazil
    J Chem Ecol 35:1212-21. 2009
    ..In addition, GC-EAD recordings showed that the antennae of males responded to several of the main components of female MG secretions...
  12. pmc Role of the major histocompatibility complex class II Ea gene in lupus susceptibility in mice
    N Ibnou-Zekri
    Department of Pathology, Centre Medical Universitaire, University of Geneva, Geneva, Switzerland
    Proc Natl Acad Sci U S A 94:14654-9. 1997
    ..that (i) the development of SLE was almost completely prevented in BXSB (H-2(b)) mice expressing two copies of the Ead transgene at the homozygous level as well as in BXSB H-2(k) (I-E+) congenic mice as for H-2(d) BXSB mice, and (ii) ..
  13. ncbi Electroantennographic and behavioral responses of the sphinx moth Manduca sexta to host plant headspace volatiles
    Ann M Fraser
    ARL Division of Neurobiology, University of Arizona, P O Box 210077, Tucson, Arizona 85721 0077, USA
    J Chem Ecol 29:1813-33. 2003
    Coupled gas chromatography with electroantennographic detection (GC-EAD) using antennae of adult female Manduca sexta was employed to screen for olfactory stimulants present in headspace collections from four species of larval host ..
  14. ncbi Aerosol probes of emphysema progression in dogs treated with all trans retinoic acid--an exploratory study
    Frank S Rosenthal
    School of Health Sciences, Purdue University, 500 Stadium Mall Drive, West Lafayette, IN 47907, USA
    J Aerosol Med 20:83-96. 2007
    ..5/FVC), an aerosol-derived measure of pulmonary airspace size (effective airspace diameter, EAD), and an aerosol-derived measure of nonuniform ventilation (aerosol dispersion, AD)...
  15. ncbi The role of late I and antiarrhythmic drugs in EAD formation and termination in Purkinje fibers
    David Fedida
    Cardiome Pharma Corporation, University of British Columbia, Vancouver, BC, Canada
    J Cardiovasc Electrophysiol 17:S71-S78. 2006
    ..of lidocaine, mexiletine, and RSD1235 may result, at least in part, from their ability to inhibit late I(Na) during action potential repolarization, and inhibition of the inward currents contributing to EAD and arrhythmia formation.
  16. doi The asymmetric molecular forms of AChE and the expression of collagen Q in mature and immature fast and slow rat muscles
    Spela Glisović
    Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Zaloska 4, 1000 Ljubljana, Slovenia
    Chem Biol Interact 187:90-5. 2010
    ..The latter is due to the nearly complete suppression of the expression of AChE-associated collagen Q (ColQ) in the extrajunctional regions of fast muscle fibers, in contrast to its ample expression in slow muscles...
  17. ncbi Drug-induced afterdepolarizations and triggered activity occur in a discrete subpopulation of ventricular muscle cells (M cells) in the canine heart: quinidine and digitalis
    S Sicouri
    Masonic Medical Research Laboratory, Utica, New York 13504
    J Cardiovasc Electrophysiol 4:48-58. 1993
    ..Epicardial, M region, and endocardial tissues and cells show distinct, sometimes opposite, responses to a variety of drugs, including those capable of inducing EADs and DADs...
  18. ncbi Volatile emissions from Aesculus hippocastanum induced by mining of larval stages of Cameraria ohridella influence oviposition by conspecific females
    A Bettina Johne
    Institute for Forest Zoology and Forest Conservation, Georg August University, Buesgenweg 3, 37077, Goettingen, Germany
    J Chem Ecol 32:2303-19. 2006
    ..Utilizing gas chromatography coupled with parallel detection by mass spectrometry and electroantennography (GC-MS/EAD), more than 30 compounds eliciting responses from antennae of C. ohridella were detected...
  19. ncbi Comparison of the in vitro electrophysiologic and proarrhythmic effects of amiodarone and sotalol in a rabbit model of acute atrioventricular block
    Peter Milberg
    Hospital of the Westfälische Wilhelms University, Department of Cardiology and Angiology and Institute for Arteriosclerosis Research, Munster, Germany
    J Cardiovasc Pharmacol 44:278-86. 2004
    ..01), but not in amiodarone-treated hearts (10%; p = ns). Sotalol led to early afterdepolarizations (EAD) and torsade de pointes (TdP) after lowering of potassium concentration (6 of 13 hearts)...
  20. ncbi Evolution of reproductive strategies in the sexually deceptive orchid Ophrys sphegodes: how does flower-specific variation of odor signals influence reproductive success?
    M Ayasse
    Institute of Zoology, University of Vienna, Austria
    Evolution 54:1995-2006. 2000
    ..active in male olfactory receptors based on gas chromatography with electroantennographic detection (GC-EAD)...
  21. ncbi The origin of the molecular diversity and functional anchoring of cholinesterases
    Jean Massoulié
    CNRS UMR 8544, Laboratoire de Neurobiologie, Ecole Normale Superieure, Paris, France
    Neurosignals 11:130-43. 2002
    ..homomeric oligomers (monomers, dimers, tetramers), as well as hetero-oligomeric assemblies with anchoring proteins, ColQ and PRiMA...
  22. ncbi Identification (GC and GC-MS) of unsaturated acetates in Elasmopalpus lignosellus and their biological activity (GC-EAD and EAG)
    Gulab N Jham
    Departamento de Quimica, Universidade Federal de Vicosa, Vicosa, MG, Brazil
    J Sep Sci 28:281-5. 2005
    ..Extract 2 was analyzed by gas chromatography (GC) and gas chromatography-electroannetography (GC-EAD) revealing the presence of (Z)-11-HDA and (Z)-9-TDA. In addition, the same compounds elicited a response with the E...
  23. ncbi [Organ changes induced by ergot derivative dopamine agonist drugs: time to change treatment guidelines in Parkinson's disease?]
    J Roth
    Centrum extrapyramidových onemocneni, Neurologická klinika 1 LF UK a VFN, Praha
    Cas Lek Cesk 144:123-6. 2005
    ..Not to use EAD as the first-line dopamine agonists. B...
  24. ncbi Electrophysiological and behavioral responses of Ips duplicatus to aggregation pheromone in Inner Mongolia, China: amitinol as a potential pheromone component
    Qing He Zhang
    Chemical Ecology, Swedish University of Agricultural Sciences, P O Box 44, 230 53 Alnarp, Sweden
    J Chem Ecol 33:1303-15. 2007
    ..gas chromatography-mass spectrometry (GC-MS), coupled gas chromatography-electroantennographic detection (GC-EAD), and field trapping bioassays in Inner Mongolia, China...
  25. ncbi [The effects of calmodulin kinase II inhibitor on ventricular arrhythmias in rabbits with cardiac hypertrophy]
    Jun Ke
    Department of Cardiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
    Zhonghua Xin Xue Guan Bing Za Zhi 35:33-6. 2007
    ..To investigate the effect of KN-93, a calmodulin kinase II inhibitor, on ventricular arrhythmias in rabbits with cardiac hypertrophy...
  26. ncbi Electrophysiological and behavioral responses of Ips subelongatus to semiochemicals from its hosts, non-hosts, and conspecifics in China
    Qing He Zhang
    Chemical Ecology, Swedish University of Agricultural Sciences, P O Box 44, SE 230 53, Alnarp, Sweden
    J Chem Ecol 33:391-404. 2007
    ..were analyzed using both gas chromatographic-electroantennographic detection (GC-EAD) and gas chromatography/mass spectrometry (GC-MS) techniques, and field trapping bioassays in Inner Mongolia, China...
  27. ncbi Online biochemical detection of glutathione-S-transferase P1-specific inhibitors in complex mixtures
    Jeroen Kool
    LACDR Division of Molecular Toxicology, Department of Pharmacochemistry, Vrije Universiteit, Amsterdam, The Netherlands
    J Biomol Screen 12:396-405. 2007
    A high-resolution screening (HRS) technology is described, which couples 2 parallel enzyme affinity detection (EAD) systems for substrates and inhibitors of rat cytosolic glutathione-S-transferases (cGSTs) and purified human GST P1 to ..
  28. doi General food semiochemicals attract omnivorous German cockroaches, Blattella germanica
    Nooshin Karimifar
    Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada
    J Agric Food Chem 59:1330-7. 2011
    ..Coupled gas chromatographic-electroantennographic detection (GC-EAD) and GC-mass spectrometric (MS) analyses of these attractive extracts, or fractions thereof, and of synthetic ..
  29. pmc Reverse and conventional chemical ecology approaches for the development of oviposition attractants for Culex mosquitoes
    Walter S Leal
    Honorary Maeda Duffey Laboratory, Department of Entomology, University of California Davis, Davis, California, United States of America
    PLoS ONE 3:e3045. 2008
    ..both CquiOBP1 as a molecular target in binding assays and gas chromatography-electroantennographic detection (GC-EAD), we identified nonanal, trimethylamine (TMA), and skatole as test compounds...
  30. doi Aphrodisiac pheromones from the wings of the small cabbage white and large cabbage white butterflies, Pieris rapae and Pieris brassicae
    Selma Yildizhan
    Institut fur Organische Chemie, Technische Universitat Braunschweig, Hagenring 30, Braunschweig, Germany
    Chembiochem 10:1666-77. 2009
    ..activity of the compounds in the extract was tested by coupled gas chromatographic-electroantennographic (GC-EAD) analysis, which showed that both macrolides and the other major components of the wings can be detected by the ..
  31. doi Prioritizing environmental health risks in the UAE
    Henry H Willis
    RAND Corporation, Pittsburgh, PA 15213, USA
    Risk Anal 30:1842-56. 2010
    ..in the United Arab Emirates (UAE) to inform a strategic planning process led by the Environment Agency-Abu Dhabi (EAD)...
  32. pmc Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function
    G Feng
    Department of Anatomy and Neurobiology, Washington University Medical School, St Louis, Missouri 63110, USA
    J Cell Biol 144:1349-60. 1999
    ..AChE) occurs in both asymmetric forms, covalently associated with a collagenous subunit called Q (ColQ), and globular forms that may be either soluble or membrane associated...
  33. ncbi Volatile attractants for the common bluebottle, Graphium sarpedon nipponum, from the host, Cinnamomum camphora
    Jing Li
    Department of Agriculture, Faculty of Agriculture, Kochi University, Monobe, Nankoku, Japan
    Biosci Biotechnol Biochem 74:1987-90. 2010
    ..The volatiles were analyzed by capillary gas chromatography with electro-antennographic detection (GC-EAD)...
  34. ncbi Autoimmunity against the second extracellular loop of beta(1)-adrenergic receptors induces early afterdepolarization and decreases in K-channel density in rabbits
    Yukiko Fukuda
    Cardiopulmonary Division of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi Shinjuku ku, Tokyo 160 8582, Japan
    J Am Coll Cardiol 43:1090-100. 2004
    ..We sought to define the electrophysiologic property of the rabbit heart associated with autoimmunity against the second extracellular loop of the beta(1)-adrenergic receptor...
  35. ncbi Atopic dermatitis, extrinsic atopic dermatitis and the hygiene hypothesis: results from a cross-sectional study
    A Zutavern
    Dr von Haunersches Kinderspital University Children s Hospital, Munich, Germany
    Clin Exp Allergy 35:1301-8. 2005
    ..AD can be differentiated into an allergic extrinsic form (EAD) and a non-allergic intrinsic form (IAD)...
  36. ncbi Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers
    He Li
    Eppley Institute and Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198 6805, USA
    Biochem J 411:425-32. 2008
    ..in the neuromuscular junctions and the central nervous system is anchored to membranes through interactions with ColQ (AChE-associated collagen tail protein) and PRiMA (proline-rich membrane anchor) proteins containing proline-rich ..
  37. pmc Assembly and regulation of acetylcholinesterase at the vertebrate neuromuscular junction
    R L Rotundo
    Department of Cell Biology and Anatomy, The University of Miami School of Medicine, 1600 N W 10th Avenue, Miami, FL 33136, USA
    Chem Biol Interact 175:26-9. 2008
    The collagen-tailed form of acetylcholinesterase (ColQ-AChE) is the major if not unique form of the enzyme associated with the neuromuscular junction (NMJ)...
  38. doi The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption
    Francoise Imbert-Bismut
    Department of Biochemistry, APHP Groupe Hospitalier Pitié Salpétrière, Paris, France
    Eur J Gastroenterol Hepatol 21:18-27. 2009
    The validity of biomarkers of excessive alcohol drinking (EAD) (30 g/day or more), such as carbohydrate-deficient transferrin (CDT%), is confounded by liver disease severity...
  39. doi Analysis of Ewing sarcoma (EWS)-binding proteins: interaction with hnRNP M, U, and RNA-helicases p68/72 within protein-RNA complexes
    Steffen Pahlich
    Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
    J Proteome Res 8:4455-65. 2009
    ..belongs to the TET family of RNA-binding proteins and consists of an N-terminal transcriptional activation domain (EAD) and a C-terminal RNA-binding domain (RBD), which is extensively methylated at arginine residues...
  40. ncbi Aerosol measurement of airspace diameter correlates with morphometry in normal and papain-exposed air dried lungs
    F S Rosenthal
    School of Health Sciences, Purdue University, West Lafayette, Indiana 47907, USA
    Exp Lung Res 25:425-41. 1999
    Aerosol measures of effective airspace diameter (EAD) were correlated with morphometric parameters in a series of 8 canine lungs, 5 of which had been exposed to papain in order to cause experimental emphysema...
  41. ncbi Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome : direct evidence from intracellular recordings in the intact left ventricular wall
    G X Yan
    Main Line Health Heart Center, Wynnewood, PA, USA
    Circulation 103:2851-6. 2001
    This study examined the role of phase 2 early afterdepolarization (EAD) in producing a trigger to initiate torsade de pointes (TdP) with QT prolongation induced by dl-sotalol and azimilide...
  42. ncbi Odor composition of preferred (buffalo and ox) and nonpreferred (waterbuck) hosts of some Savanna tsetse flies
    Nicholas K Gikonyo
    International Centre of Insect Physiology and Ecology, Nairobi, Kenya
    J Chem Ecol 28:969-81. 2002
    ..octadecyl bonded) silica and analyzed with a gas chromatography-linked electroantennographic detector (GC-EAD) and, where possible, identified by using gas chromatography-linked mass spectrometry (GC-MS) and chromatographic ..
  43. ncbi Neuropathologic substrate of mild cognitive impairment
    William R Markesbery
    Alzheimer s Disease Center, University of Kentucky, Lexington, KY 40536 0230, USA
    Arch Neurol 63:38-46. 2006
    To define the neuropathologic findings in amnestic mild cognitive impairment (MCI) and early Alzheimer disease (EAD).
  44. ncbi Sodium-calcium exchange initiated by the Ca2+ transient: an arrhythmia trigger within pulmonary veins
    Eugene Patterson
    University of Oklahoma Health Sciences Center and the DVA Medical Center, Oklahoma City, Oklahoma, USA
    J Am Coll Cardiol 47:1196-206. 2006
    ....
  45. ncbi Spontaneous pulmonary vein firing in man: relationship to tachycardia-pause early afterdepolarizations and triggered arrhythmia in canine pulmonary veins in vitro
    Eugene Patterson
    University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
    J Cardiovasc Electrophysiol 18:1067-75. 2007
    ..Rapid firing originating within pulmonary veins (PVs) initiates atrial fibrillation (AF). The following studies were performed to evaluate spontaneous PV firing in patients with AF to distinguish focal versus reentrant mechanisms...
  46. pmc Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2
    Carl Sims
    University of Pittsburgh, School of Medicine, Department of Cell Biology and Physiology, Pittsburgh, PA 15261, USA
    Circ Res 102:e86-100. 2008
    ..Therefore, sex, age, and regional differences in I(Ca,L) density and in EAD susceptibility were analyzed in epicardial left ventricular myocytes isolated from the apex and base of prepubertal ..
  47. ncbi [Effects of BmKIM on sodium current of isolated cardiomyocytes, transmembrane action potential and aconitine induced arrhythmia in vivo in rabbits]
    Teng Wang
    Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China
    Zhonghua Xin Xue Guan Bing Za Zhi 37:102-7. 2009
    ....
  48. pmc CCAAT/enhancer binding protein alpha binds to the Epstein-Barr virus (EBV) ZTA protein through oligomeric interactions and contributes to cooperative transcriptional activation of the ZTA promoter through direct binding to the ZII and ZIIIB motifs during
    Frederick Y Wu
    Molecular Virology Laboratories, Department of Pharmacology and Molecular Sciences, School of dicine, The Johns Hopkins University, Baltimore, Maryland 21231 1000, USA
    J Virol 78:4847-65. 2004
    ..Finally, double-label immunofluorescence assays suggested that EAD protein expression was activated even better than ZTA expression in latently infected C/EBPalpha-transfected Akata ..
  49. ncbi Expression and localization of acetylcholinesterase at the neuromuscular junction
    Richard L Rotundo
    Department of Cell Biology and Anatomy and Neuroscience Program, University of Miami School of Medicine, Miami, Florida 33136, USA
    J Neurocytol 32:743-66. 2003
    ..large protein consists of three catalytic tetramers covalently linked to the three-stranded collagen-like tail (ColQ)...
  50. ncbi Increasing gap junction coupling reduces transmural dispersion of repolarization and prevents torsade de pointes in rabbit LQT3 model
    Xiao Qing Quan
    Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    J Cardiovasc Electrophysiol 18:1184-9. 2007
    ..This study examined the effects of antiarrhythmic peptide AAP10, a gap junction enhancer, on TDR and induction of TdP in a rabbit LQT3 model...
  51. doi Viral vector-mediated [corrected] expression of human collagen Q in cultured cells
    Mikako Ito
    Division of Neurogenetics, Center for Neurological Diseases and Cancer, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa Ku, Nagoya, Japan
    Chem Biol Interact 175:346-8. 2008
    ..Collagen Q (ColQ) makes a triple helical structure and anchors the catalytic subunit of acetylcholinesterase (AChE) to the synaptic ..
  52. doi Training veterinary personnel for effective identification and diagnosis of exotic animal diseases
    Carmel M Kerwick
    J Vet Med Educ 35:255-61. 2008
    The requirements for exotic animal disease (EAD) training were considered at a workshop organized for those with responsibilities for EAD response management in the different states of Australia, with the objective of identifying the ..
  53. doi Composition and electrophysiological activity of constituents identified in male wing gland secretion of the bumblebee parasite Aphomia sociella
    Blanka Kalinová
    Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nam 2, CZ 166 10 Praha 6, Czech Republic
    J Nat Prod 72:8-13. 2009
    ..gas chromatography, electroantennography (EAG), gas chromatography with electroantennographic detection (GC-EAD), and NMR...
  54. pmc Fever accentuates transmural dispersion of repolarization and facilitates development of early afterdepolarizations and torsade de pointes under long-QT Conditions
    Alexander Burashnikov
    Masonic Medical Research Laboratory, Utica, NY 13501, USA
    Circ Arrhythm Electrophysiol 1:202-8. 2008
    ..The present study examines the effect of hyperthermia on transmural dispersion of action potential duration (TD-APD), early afterdepolarization (EAD) activity, and torsade de pointes (TdP) under long-QT conditions.
  55. ncbi [Molecular bases and therapeutic strategies in defective neuromuscular transmissions: lessons learned from a prototypical synapse]
    Kinji Ohno
    Division of Neurogenetics, Nagoya University Graduate School of Medicine, Showa Ku, Nagoya, Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 29:145-51. 2009
    ..1) Defects in choline acetyltransferase reduce acetylcholine contents at the nerve terminal. (2) Collagen Q (ColQ) anchors acetylcholinesterase at the synaptic basal lamina, and its defects cause endplate acetylcholinesterase ..
  56. ncbi (Z,Z)-4,7-tridecadien-(S)-2-yl acetate: sex pheromone of Douglas-fir cone gall midge, Contarinia oregonensis
    Regine Gries
    Centre for Environmental Biology, Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, V5A 1S6 Canada
    J Chem Ecol 28:2283-97. 2002
    ..Coupled gas chromatographic-electroantennographic detection (GC-EAD) analyses of pheromone extract revealed a single compound (A) that elicited responses from male antennae...
  57. ncbi Analysis of chromosome aberrations in nuclear-power-plant workers considering the lifetime of lymphocytes
    H W Chung
    School of Public Health, Seoul National University, Korea
    Int J Radiat Biol 76:923-7. 2000
    ..To analyse chromosome aberrations in nuclear-power-plant workers taking account of the mean lifetime of lymphocytes (MLTL)...
  58. ncbi A new supraglottic airway, the Elisha Airway Device: a preliminary study
    Sonia J Vaida
    Department of Anesthesiology, Bnai Zion Medical Center, Haifa, Israel
    Anesth Analg 99:124-7. 2004
    We describe the Elisha Airway Device (EAD), a new reusable supraglottic ventilatory device...
  59. ncbi Performance of two new electrochemical treatment systems for wastewaters
    Chuanping Feng
    Science and Technology Promotion Foundation of Ibaraki, Tsukuba, Ibaraki, Japan
    J Environ Sci Health A Tox Hazard Subst Environ Eng 39:2533-43. 2004
    ..A series of experiments was performed using effluents from an anaerobic digester (EAD) of cattle wastewater, supernatants from primary sedimentation in a sewage plant (SPS), and domestic wastewater to ..
  60. ncbi Mastrus ridibundus parasitoids eavesdrop on cocoon-spinning codling moth, Cydia pomonella, larvae
    Zaid Jumean
    Department of Biological Sciences, Simon Fraser University, Burnaby, BC V5A1S6, Canada
    Naturwissenschaften 92:20-5. 2005
    ..In gas chromatographic-electroantennographic detection (GC-EAD) analyses of bioactive Porapak Q extract of cocoon-derived airborne semiochemicals, ten compounds elicited ..
  61. ncbi Improvement pattern in the clock drawing test in early Alzheimer's disease
    Jesus Cacho
    Section of Neurology, Salamanca University Hospital, Salamanca, Spain
    Eur Neurol 53:140-5. 2005
    The aim of this paper was to compare the performance of a group of patients with early Alzheimer's disease (EAD) against a control group of healthy control (HC) subjects in the Clock Drawing Test (CDT), i.e...
  62. ncbi Mechanisms underlying the effects of the pyrethroid tefluthrin on action potential duration in isolated rat ventricular myocytes
    C Ian Spencer
    Division of Pulmonary and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Pharmacol Exp Ther 315:16-23. 2005
    ..In some action potentials, tefluthrin also activated early after-depolarizations (EADs). Using a selected EAD-containing action potential clamp, we observed that EADs could evoke a Cd2+-sensitive membrane current (I(EAD)) ..
  63. ncbi Enteral access in home care
    Mark H Delegge
    Coram Healthcare, Section of Nutrition, Digestive Disease Center, Medical University of South Carolina, South Carolina, USA
    JPEN J Parenter Enteral Nutr 30:S13-20. 2006
    ..For those patients who cannot or will not swallow, an enteral access device (EAD) is required. Some of these devices can be passed through the oral or nasal cavity into the stomach or small bowel...
  64. ncbi [Characteristics of the action potentials and the underlying ionic mechanisms in the cardiomyocytes from rabbit pulmonary vein sleeves]
    Huai Yu Ding
    Heart Center, Beijing Chaoyang Hospital Affiliated to the Capital University of Medical Sciences, Beijing 100020, China
    Sheng Li Xue Bao 58:129-35. 2006
    ..a second plateau response could be induced easily, suggesting a strong tendency of early afterdepolarization (EAD) genesis in PVC. Non-selective cation current (I(NSCC)) was first recorded in both LAC and PVC...
  65. doi The characteristics of action potential and nonselective cation current of cardiomyocytes in rabbit superior vena cava
    Pan Wang
    Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
    Sci China C Life Sci 51:326-35. 2008
    ..showed slow response action potentials with automatic activity and some others showed early after depolarization (EAD) spontaneously...
  66. pmc Detecting navigational deficits in cognitive aging and Alzheimer disease using virtual reality
    Laura A Cushman
    Department of Neurology, Brain and Cognitive Sciences, Center for Visual Science, The University of Rochester Medical Center, Rochester, NY14642, USA
    Neurology 71:888-95. 2008
    ..Here we compare our previously described real-world navigation test with a virtual reality (VR) version simulating the same navigational environment...
  67. ncbi [Distribution and risk factors of steno-occlusive lesions in patients with ischemic cerebrovascular disease]
    Dou Li
    Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing, China
    Zhonghua Yi Xue Za Zhi 88:1158-62. 2008
    ..To investigate the distribution of atherosclerotic steno-occlusive lesions in Chinese patients with ischemic cerebrovascular disease and the risk factors for occlusive lesions of intracranial and extracranial arteries...
  68. doi Early experience with percutaneous cryoablation of extra-abdominal desmoid tumors
    Jennifer L Kujak
    Department of Radiology, Mayo Clinic Arizona, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA
    Skeletal Radiol 39:175-82. 2010
    ..resection, radiation therapy and chemotherapy are all accepted as standard treatments for extra-abdominal desmoid (EAD) tumors, but their effectiveness has been limited by frequent local recurrence...
  69. doi Methyl 6-methylsalicylate: a female-produced pheromone component of the parasitoid wasp Spalangia endius
    William J Nichols
    Department of Biological Sciences, Northern Illinois University, DeKalb, IL 60115, USA
    J Chem Ecol 36:1140-7. 2010
    ..Male antennae were sensitive to both compounds in electrophysiological tests (GC-EAD)...
  70. doi Peripheral modulation of pheromone response by inhibitory host compound in a beetle
    Martin N Andersson
    Chemical Ecology, Department of Plant Protection Biology, Swedish University of Agricultural Sciences, SE 230 53 Alnarp, Sweden
    J Exp Biol 213:3332-9. 2010
    We identified several compounds, by gas chromatographic-electroantennographic detection (GC-EAD), that were antennally active in the bark beetle Ips typographus and also abundant in beetle-attacked spruce trees...
  71. pmc Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts
    Norishige Morita
    Translational Arrhythmia Research Section, Cardiovascular Research Laboratory, David Geffen School of Medicine at UCLA, 675 Charles E Young Dr South, MRL 3645 Mail Code 176022, Los Angeles, CA 90095, USA
    Am J Physiol Heart Circ Physiol 301:H180-91. 2011
    ..We sought to determine whether GI promotes triggered activity by early afterdepolarization (EAD) or delayed afterdepolarizations in intact hearts isolated from adult and aged rats...
  72. ncbi Does the association of 18F-FDG uptake intensity and lesion topography reveal histological phenotype and tumor differentiation in esophageal cancer?
    Alessio Imperiale
    Service de Biophysique et de Medecine Nucleaire, Hopital de Hautepierre, Hopitaux Universitaires de Strasbourg, Avenue Moliere, 67098 Strasbourg, France
    Hell J Nucl Med 14:239-42. 2011
    ..practice, the esophageal squamous cell cancer (ESCC) is considered to be more (18)F-FDG avid than adenocarcinoma (EAD)...
  73. doi Identification of male-produced aggregation pheromone of the curculionid beetle Sternechus subsignatus
    Bianca G Ambrogi
    Laboratório de Semioquímicos, Departamento de Quimica, Universidade Federal do Parana, CP 19081, CEP 81531 990, Curitiba, PR, Brazil
    J Chem Ecol 38:272-7. 2012
    ..subsignatus in olfactometer bioassays. Studies are in progress to evaluate the biological activity of the major component and the EAD-active mixture under field conditions.
  74. doi Identification and field evaluation of pear fruit volatiles attractive to the oriental fruit moth, Cydia molesta
    Peng Fei Lu
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, People s Republic of China
    J Chem Ecol 38:1003-16. 2012
    ..Attractiveness of synthetic blends to adults based on gas chromatography-electroantennogram detection (GC-EAD) activity was investigated in both field and laboratory...
  75. doi Characterization of epoxytrienes derived from (3Z,6Z,9Z)-1,3,6,9-tetraenes, sex pheromone components of arctiid moths and related compounds
    Rei Yamakawa
    Graduate School of Bio Applications and Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184 8588, Japan
    J Chem Ecol 38:1042-9. 2012
    ..GC-EAD analysis of the optically pure epoxides showed that the antennae of male H...
  76. doi Pregnancy in congenital myasthenic syndrome
    L Servais
    Service of therapeutic trials and databases, Institut de Myologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    J Neurol 260:815-9. 2013
    ..We report on 17 pregnancies in eight patients with CMS with mutations in CHRNA1, CHRNE, CHRND, GFPT1, COLQ, or DOK7...
  77. ncbi Female sex pheromone secreted by Carmenta mimosa (Lepidoptera: Sesiidae), a biological control agent for an invasive weed in Vietnam
    Le Van Vang
    Department of Plant Protection, College of Agriculture and Applied Biology, Can Tho University, Can Tho City, Vietnam
    Biosci Biotechnol Biochem 76:2153-5. 2012
    ..which is one of the most invasive weeds in Vietnam. GC-EAD and GC-MS analyses of a pheromone gland extract revealed that the female moths produced (3Z,13Z)-3,13-..
  78. doi Circadian release of male-specific components of the greater date moth, Aphomia (Arenipses) sabella, using sequential SPME/GC/MS analysis
    Anat Levi-Zada
    Institute of Plant Protection, Agricultural Research Organization, Volcani Center, Bet Dagan, 50250, Israel
    J Chem Ecol 40:236-43. 2014
    ..This is the first finding of a circadian release of male-specific compounds in moths. GC/EAD analyses with synthetic standards of compounds released by males showed that the female antenna is stimulated by ..
  79. doi Enhanced digestion of waste activated sludge using microbial electrolysis cells at ambient temperature
    Joseph R Asztalos
    Department of Civil Engineering, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada
    Water Res 87:503-12. 2015
    ..Two lab-scale digesters, a control anaerobic digester and an electrically-assisted digester (EAD - equipped with a MEC bioanode and cathode) were operated under three solids retention times (SRT = 7, 10 and 14 ..
  80. doi Early Allograft Dysfunction After Liver Transplantation Is Associated With Short- and Long-Term Kidney Function Impairment
    H M Wadei
    Mayo Clinic Collaborative in Transplant Research and Outcomes, Department of Transplant, Mayo Clinic Florida, Jacksonville, FL
    Am J Transplant 16:850-9. 2016
    Early allograft dysfunction (EAD) after liver transplantation (LT) is related to ischemia-reperfusion injury and may lead to a systemic inflammatory response and extrahepatic organ dysfunction...
  81. pmc The Drosophila Imaginal Disc Tumor Model: Visualization and Quantification of Gene Expression and Tumor Invasiveness Using Genetic Mosaics
    Juliane Mundorf
    Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases CECAD, University of Cologne
    J Vis Exp . 2016
    ..how to generate fluorescently labeled clonal tumors of varying malignancy in the eye/antennal imaginal discs (EAD) of Drosophila larvae using the Mosaic Analysis with a Repressible Cell Marker (MARCM) technique...
  82. pmc Exhaust Air Dust Monitoring is Superior to Soiled Bedding Sentinels for the Detection of Pasteurella pneumotropica in Individually Ventilated Cage Systems
    Manuel Miller
    Research Unit for Comparative Medicine, Helmholtz Zentrum Mnchen, German Research Center for Environmental Health, Neuherberg, Germany, Email
    J Am Assoc Lab Anim Sci 55:775-781. 2016
    ..In this study, we investigated whether analysis of exhaust air dust (EAD) samples by using a sensitive and specific real-time PCR assay is superior to conventional SBS monitoring for the ..
  83. ncbi Cytoskeleton proteins in CSF distinguish frontotemporal dementia from AD
    M Sjogren
    Institute of Clinical Neuroscience, Goteborg University, Sweden
    Neurology 54:1960-4. 2000
    ..Both proteins have been implicated in the pathophysiology of FTD...
  84. pmc Differences in action potential and early afterdepolarization properties in LQT2 and LQT3 models of long QT syndrome
    C R Studenik
    Institute of Pharmacology and Toxicology, University of Vienna, Vienna, Austria
    Br J Pharmacol 132:85-92. 2001
    ..Action potential and early afterdepolarization (EAD) properties were rigorously defined by the frequency power spectra obtained with fast Fourier transforms. 3...
  85. ncbi Spontaneous, electrically, and cesium chloride induced arrhythmia and afterdepolarizations in the rapidly paced dog heart
    D L Jones
    Departments of Physiology and Medicine, University of Western Ontario, London, Ontario, Canada, N6A 5C1
    Pacing Clin Electrophysiol 24:474-85. 2001
    ..induced arrhythmia and the susceptibility of the failing dog heart to arrhythmia and early afterdepolarization (EAD) induced triggered activity elicited by exogenous administration of cesium chloride (CsCl)...
  86. ncbi Volatiles associated with preferred and nonpreferred hosts of the Nantucket pine tip moth, Rhyacionia frustrana
    C Asaro
    Department of Entomology, University of Georgia, 413 Biological Sciences, Athens, Georgia 30602, USA
    J Chem Ecol 30:977-90. 2004
    ..frustrana host preference. Gas chromatographic-electroantennographic detection (GC-EAD) analyses of standards identified 19 different seedling-associated compounds that elicited antennal responses from ..
  87. ncbi Alterations in zinc transporter protein-1 (ZnT-1) in the brain of subjects with mild cognitive impairment, early, and late-stage Alzheimer's disease
    M A Lovell
    Sanders Brown Center on Aging and Departments of Chemistry, Neurology and Pathology, University of Kentucky, Lexington, KY 40536, USA
    Neurotox Res 7:265-71. 2005
    ..levels in the HPG, SMTG and CER of 5 subjects with mild cognitive impairment (MCI), 5 subjects with early AD (EAD) and 4 appropriately age-matched controls. Western blot and dot-blot analysis showed statistically significant (p 0...
  88. ncbi 1,4-Dimethoxybenzene, a floral scent compound in willows that attracts an oligolectic bee
    Stefan Dötterl
    Department of Plant Systematics, University of Bayreuth, 95440 Bayreuth, Germany
    J Chem Ecol 31:2993-8. 2005
    ..and the samples were subsequently analyzed by coupled gas chromatographic-electroantennographic detection (GC-EAD) to detect possible attractants of A. vaga...
  89. pmc Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins
    King Pan Ng
    Department of Biology, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, S A R China
    Proc Natl Acad Sci U S A 104:479-84. 2007
    ..more than a decade ago, molecular analysis has been greatly hindered by the repetitive EWS activation domain (EAD) structure, containing multiple degenerate hexapeptide repeats (consensus SYGQQS) with a conserved tyrosine residue...
  90. ncbi [Cardiopulmonary resuscitation with semi-automated external defibrillator: assessment of the teaching-learning process]
    Ana Maria Kazue Miyadahira
    Departamento de Enfermagem Médico Cirúrgica da Escola de Enfermagem, Universidade de São Paulo EEUSP, Sao Paulo, SP, Brasil
    Rev Esc Enferm USP 42:532-8. 2008
    ..sample was composed of 40 administrative workers of a public institution that were trained on CPR technique using EAD, as an experiment...
  91. doi Role of oxidative stress in the progression of Alzheimer's disease
    Rukhsana Sultana
    Department of Chemistry, Center of Membrane Sciences, and Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40506 0055, USA
    J Alzheimers Dis 19:341-53. 2010
    ..the appearance of the same oxidized brain proteins from subjects with mild cognitive impairment (MCI), early AD (EAD), and late-stage AD, and relating these findings to the reported AD pathology...
  92. pmc Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells
    Tarvo Rajasalu
    Department of Internal Medicine I, University Hospital of Ulm, Ulm, Germany
    Diabetes 59:1966-73. 2010
    ..established model to characterize preproinsulin-specific CD8 T-cell responses and experimental autoimmune diabetes (EAD)...
  93. pmc Rapid multiplex detection and differentiation of Listeria cells by use of fluorescent phage endolysin cell wall binding domains
    Mathias Schmelcher
    Institute of Food, Nutrition and Health, ETH Zurich, Schmelzbergstrasse, 7, CH 8092 Zurich, Switzerland
    Appl Environ Microbiol 76:5745-56. 2010
    ..These proteins feature a modular organization, consisting of an N-terminal enzymatically active domain (EAD), which contributes lytic activity, and a C-terminal cell wall binding domain (CBD), which targets the lysin to its ..
  94. pmc A transcription assay for EWS oncoproteins in Xenopus oocytes
    King Pan Ng
    Department of Biology, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon Hong Kong, China
    Protein Cell 1:927-34. 2010
    ..EFPs are potent transcriptional activators, dependent on the N-terminal region of EWS (the EWS-activation-domain, EAD) and this function is thought to be central to EFT oncogenesis and maintenance...
  95. pmc Identification of mosquito repellent odours from Ocimum forskolei
    Teun Dekker
    Division of Chemical Ecology, Department of Crop Science, Swedish University of Agricultural Sciences PO 44, Alnarp, SE 23053, Sweden
    Parasit Vectors 4:183. 2011
    ..We verified whether active repellent compounds could be identified using gas-chromatography coupled electroantennogram recordings (GC-EAD) with headspace extracts of crushed plants.
  96. pmc Early Alzheimer's disease blocks responses to accelerating self-movement
    Roberto Fernandez
    Department of Neurology, Brain and Cognitive Sciences, University of Rochester Medical Center, Rochester, NY 14642 0673, USA
    Neurobiol Aging 33:2551-60. 2012
    ..Young (YNC) and older (ONC) normal controls, and early AD patients (EAD) viewed real-world videos and dot motion stimuli simulating self-movement scenes...
  97. doi Controlling equine influenza: policy networks and decision-making during the 2007 Australian equine influenza outbreak
    K Schemann
    Faculty of Veterinary Science, The University of Sydney, Camden, NSW, Australia
    Transbound Emerg Dis 61:449-63. 2014
    ..Training to increase awareness and knowledge of emergency animal diseases (EADs) and response systems will improve stakeholder participation in emergency disease management and preparedness for future EAD incursions.
  98. doi Early allograft dysfunction is associated with excess resource utilization after liver transplantation
    K P Croome
    Multi Organ Transplant Program, London Health Sciences Centre, Western University, London, Ontario, Canada
    Transplant Proc 45:259-64. 2013
    ..The primary objective of this study was to examine the relationship between early allograft dysfunction (EAD) and LOS after LT...
  99. doi (6R,10S)-Pallantione: the first ketone identified as sex pheromone in stink bugs
    Carla F Fávaro
    Universidade Federal do Parana, 81531 990 Curitiba PR, Brazil
    Org Lett 15:1822-5. 2013
    ..The biological activity of the synthetic pheromone was demonstrated by behavioral and EAD experiments...
  100. pmc Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve
    Zhilin Qu
    Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Cardiovasc Res 99:6-15. 2013
    ..However, this generalized condition is not sufficient for EAD genesis and does not explain the voltage oscillations manifesting as EADs...

Research Grants27

  1. RICARDO ANIBAL MASELLI; Fiscal Year: 2014
    ..receptor (AChR) subunit genes (CHRNA1, CHRNB1, CHRND, CHRNE), and the acetylcholinesterase (AChE) collagenic tail (COLQ) were shown to cause several forms of CMS...
  2. Lai Hua Xie; Fiscal Year: 2015
    ..Pathological concentrations of H2O2 causes early afterdepolarization (EAD), delayed afterdepolarization (DAD), and triggered activity (TA), and has been suggested as a potential ..
  3. LAURA ANNE JACOX; Fiscal Year: 2015
    ..The mouth develops from the "extreme anterior domain" (EAD), where the ectoderm and endoderm directly juxtapose...
  4. Sanda Despa; Fiscal Year: 2015
    ..larger cellular and sarcoplasmic reticulum (SR) Ca load and increased frequency of early afterdepolarizations (EAD) and delayed afterdepolarizations (DAD)...
  5. The role of dynamic changes in repolarization and calcium transients in Long QT r
    Bum Rak Choi; Fiscal Year: 2013
    ..QT related arrhythmias including tissue characteristics as substrate for reentry and conditions that exacerbate EAD inductions and pVTs...
  6. Gideon Koren; Fiscal Year: 2016
    ..tissue heterogeneities mediate the R-on-T phenomenon as well as test whether short-long-short sequence increases EAD formations and tissue heterogeneities, thus self propels until the onset of TdP and weather TdP and PVT are ..
  7. Modeling of Cardiac Calcium Dynamics;Ryanodine Receptor induced Arrhythmias
    Daisuke Sato; Fiscal Year: 2013
    ..2) how an EAD or DAD from a single cell can cause a group of cells to simultaneously generate EADs or DADs to exceed the critical ..
  8. ROLE OF PROLONGED REPOLARIZATION IN CARDIAC ARRHYTHMIAS
    Dan Roden; Fiscal Year: 1992
    ..One of the most important findings to date is that ventricular muscle blunts the action potential prolongation and EAD induction by quinidine in Purkinje tissue...
  9. MECHANISMS OF CARDIOTOXICITY OF ANTIPSYCHOTIC DRUGS
    David Flockhart; Fiscal Year: 2001
    ..perfused heart using the characteristics of the action potential (AP), QT interval and early after depolarization (EAD) occurrence...
  10. Mechanisms for SIV evasion of vaccine immunity: Role of FasL-mediated cell death
    CHARLES PAUZA; Fiscal Year: 2009
    ..are mounting anti-viral immune responses may be important in the failure to contain the initial viremia, and may ead to the establishment of persistent infection with chronic disease...
  11. Maria T Britto; Fiscal Year: 2014
    ..Through this research, we will gather data on feasibility, usability and efficacy of the intervention that will ead to a future R01 application to examine the intervention's efficacy in a fully powered randomized trial.
  12. H-Tunneling in Methylmalonyl-CoA Mutase
    Ruma Banerjee; Fiscal Year: 2004
    ..values for the ratio of the Arrhenius preexponential factors (AH/AD) and for the difference in activation energies (EaD-EaH) that lie well outside the semiclassical range...
  13. CALMODULIN KINASE II AND EARLY AFTERDEPOLARIZATIONS
    Mark Anderson; Fiscal Year: 2007
    ..for many EADs, but ICa also provides intracellular Ca2+ ([Ca2+]i) for activating signaling molecules linked to EAD initiation...
  14. EARLY AFTER DEPOLARIZATIONS--MECHANISM/ROLE OF CALCIUM
    Craig January; Fiscal Year: 1993
    ..in voltage clamped and non-voltage clamped Purkinje strands with this model have permitted us to hypothesize that EAD induction 1 requires: 1) Lengthening and flattening of the action potential plateau within a voltage range where, 2)..
  15. Fax to Quit: Linking Smokers Visiting Clinics to State Quitlines
    Michael Fiore; Fiscal Year: 2009
    ..evaluate two forms of Fax to Quit: Fax to Quit alone (FQ) and Fax to Quit plus Enhanced Academic Detailing (FQ + EAD) with EAD comprising ongoing training/technical assistance and performance feedback...
  16. REGULATION OF ACETYLCHOLINESTERASE SYNTHESIS & ASSEMBLY
    RICHARD ROTUNDO; Fiscal Year: 2009
    ..This includes the interactions of ColQ with the muscle-specific kinase MuSK using co-expression and overexpression of these various proteins...
  17. Acetylcholinesterase: A Comparative Biochemical Approach
    Leo Pezzementi; Fiscal Year: 2005
    ..abstract_text> ..
  18. RESPONSE OF THE AGING NERVOUS SYSTEM TO TRAUMA
    Stephen Scheff; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  19. NERVE SPROUTING AND ELECTRICAL REMODELING
    Peng Sheng Chen; Fiscal Year: 2003
    ..These studies may lead to novel insights into the mechanisms of ventricular arrhythmogenesis after MI and may help develop new methods for arrhythmia control. ..
  20. DISRUPTION OF ZINC HOMEOSTASIS IN ALZHEIMER'S DISEASE
    Mark Lovell; Fiscal Year: 2004
    ....
  21. THE INTERPLAY BETWEEN HEPATIC GROWTH AND METABOLISM
    Kim Olthoff; Fiscal Year: 2004
    ..The applicant will assess basic parameters of glucose metabolism in IGFBP-1 null mice and determine the basis for any abnormalities. ..
  22. Mechnaisms of Late Sodium Current in Failing Heart
    Albertas Undrovinas; Fiscal Year: 2006
    ..Knowledge derived from the present proposal may reveal novel targets for the treatment of life-threatening arrhythmias associated with chronic HF. ..
  23. Fibrillation and Defibrillation
    Peng Sheng Chen; Fiscal Year: 2010
    ..Our preliminary studies showed that late phase 3 EAD may also play a role in postshock arrhythmias in failing and ischemic hearts...
  24. Functional Coupling between Ito and ICa in Cardiomyocytes
    Yanggan Wang; Fiscal Year: 2010
    ..The proposed study implicates a cell membrane potassium channel (Ito) in regulating the cellular calcium influx channel (ICa) function, which may decipher a new mechanism for this morbid disease. ..
  25. SYNAPTIC CHANGE IN MILD COGNITIVE IMPAIRMENT
    Stephen W Scheff; Fiscal Year: 2010
    ..Successful completion of the proposed studies will lead to new insights into the mechanisms underlying MCI and early AD and contribute to the development of effective pharmacologic therapies for AD. ..
  26. Liver Regeneration in the Transplant Setting
    KIM MARIE OLTHOFF; Fiscal Year: 2010
    ..Understanding the mechanistic biology of graft recovery and pathways of liver regeneration will provide important data for designing treatment modalities that will prevent injury and enhance recovery and regeneration. ..
  27. TRAUMATIC BRAIN INJURY AND CELLULAR HOMEOSTASIS
    Stephen Scheff; Fiscal Year: 2003
    ..These studies will significantly enhance our understanding of the mechanisms following TBI and hopefully lead to therapies resulting in increased recovery. ..