CKLFSF1

Summary

Gene Symbol: CKLFSF1
Description: CKLF like MARVEL transmembrane domain containing 1
Alias: CKLFH, CKLFH1, CKLFSF1, CKLF-like MARVEL transmembrane domain-containing protein 1, chemokine-like factor super family 1, chemokine-like factor superfamily 1, chemokine-like factor superfamily member 1, chemokine-like factor-like protein CKLFH1
Species: human

Top Publications

  1. doi CMTM1_v17 is a novel potential therapeutic target in breast cancer
    Jing Wang
    Department of Immunology, Center for Human Disease Genomics, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing 100191, P R China
    Oncol Rep 32:1829-36. 2014
  2. doi Systematic investigation of CMTM family genes suggests relevance to glioblastoma pathogenesis and CMTM1 and CMTM3 as priority targets
    Sabit Delic
    Department of Neuropathology, Regensburg University Hospital, Regensburg, Germany
    Genes Chromosomes Cancer 54:433-43. 2015
  3. ncbi Cancer Research Advance in CKLF-like MARVEL Transmembrane Domain Containing Member Family (Review)
    Jia Lu
    School of Basic Medical Hebei Medical University, Beijing, China E mail
    Asian Pac J Cancer Prev 17:2741-4. 2016
  4. ncbi Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation
    Wenling Han
    Center for Human Disease Genomics, Peking University, 38 Xueyuan Road, Beijing 100083, China
    Genomics 81:609-17. 2003
  5. ncbi Predicting polymerase II core promoters by cooperating transcription factor binding sites in eukaryotic genes
    Xiao Tu Ma
    School of Mathematical Sciences, Peking University and Center for Theoretical Biology, Beijing, China
    Acta Biochim Biophys Sin (Shanghai) 36:250-8. 2004
  6. ncbi Last intron of the chemokine-like factor gene contains a putative promoter for the downstream CKLF super family member 1 gene
    Mingxu Xu
    Laboratory of Medical Immunology, School of Basic Medical Science, Peking University, 38 Xueyuan Road, Beijing 100083, PR China
    Biochem Biophys Res Commun 313:135-41. 2004
  7. ncbi Molecular cloning and characterization of chemokine-like factor super family member 1 (CKLFSF1), a novel human gene with at least 23 alternative splicing isoforms in testis tissue
    Lu Wang
    Peking University Center for Human Disease Genomics, 38 Xueyuan Road, Beijing 100083, China
    Int J Biochem Cell Biol 36:1492-501. 2004
  8. ncbi A functional promoter region of the CKLFSF2 gene is located in the last intron/exon region of the upstream CKLFSF1 gene
    Mingxu Xu
    Laboratory of Medical Immunology, School of Basic Medical Science, Peking University, Beijing 100083, China
    Int J Biochem Cell Biol 37:1296-307. 2005
  9. ncbi CKLFSF2 is highly expressed in testis and can be secreted into the seminiferous tubules
    Shuang Shi
    Laboratory of Medical Immunology, School of Basic Medical Science, Peking University, 38 Xueyuan Road, Beijing 100083, China
    Int J Biochem Cell Biol 37:1633-40. 2005
  10. ncbi Molecular cloning and identification of mouse Cklfsf2a and Cklfsf2b, two homologues of human CKLFSF2
    Ting Li
    Peking University Center for Human Disease Genomics, 38 Xueyuan Road, Beijing 100083, China
    Int J Biochem Cell Biol 38:420-9. 2006

Scientific Experts

  • Dalong Ma
  • Wenling Han
  • Lu Wang
  • Ting Li
  • Mingxu Xu
  • Yingmei Zhang
  • Peiguo Ding
  • Xiaoyan Qiu
  • Xiaoning Mo
  • Ying Wang
  • Shuang Shi
  • Min Rui
  • Quansheng Song
  • Jia Lu
  • Sabit Delic
  • Jing Wang
  • Markus Plate
  • Yu Wang
  • Bing Mei Zhu
  • Ji Zhong
  • Xiaohui Zhu
  • Tian Yang
  • Yanan Liu
  • Xiao Tu Ma
  • Ying Zheng
  • Nan Sun
  • Kai Hua Zhang
  • Liang Li
  • Wen Jian Li
  • Song Zhang
  • Ya Bo Zhou
  • Heng Shu Wang
  • Wei Liu
  • Wei Zheng
  • Bing Xin Pang
  • Qian qian Wu
  • Anja Katrin Bosserhoff
  • Martin A Proescholdt
  • Peter Dietrich
  • Andreas Thuy
  • Markus Schulze
  • Markus J Riemenschneider
  • Guoying Zhang
  • Yang Luo
  • Quan sheng Song
  • Yu Ling Zhou
  • Dazhen Liu
  • Yishan Gao
  • Pei Zhang
  • Songhua Yang
  • Qini Gan
  • Shanhong Cheng
  • Hai Xu Tang
  • Min Ping Qian
  • Xiaotu Ma
  • Yinmei Zhang
  • Li Wang
  • Hui Fan
  • Mingping Qian
  • Bingfeng Lv
  • Chunxiao Wu
  • Donglan Xia
  • Yingyu Chen

Detail Information

Publications13

  1. doi CMTM1_v17 is a novel potential therapeutic target in breast cancer
    Jing Wang
    Department of Immunology, Center for Human Disease Genomics, School of Basic Medical Sciences, Health Science Center, Peking University, Beijing 100191, P R China
    Oncol Rep 32:1829-36. 2014
    ....
  2. doi Systematic investigation of CMTM family genes suggests relevance to glioblastoma pathogenesis and CMTM1 and CMTM3 as priority targets
    Sabit Delic
    Department of Neuropathology, Regensburg University Hospital, Regensburg, Germany
    Genes Chromosomes Cancer 54:433-43. 2015
    ..Using a human phosphokinase protein expression profiling assay, we can provide first insights into signalling of these two genes that might be conveyed by growth factor receptor, Src family kinase and WNT activation...
  3. ncbi Cancer Research Advance in CKLF-like MARVEL Transmembrane Domain Containing Member Family (Review)
    Jia Lu
    School of Basic Medical Hebei Medical University, Beijing, China E mail
    Asian Pac J Cancer Prev 17:2741-4. 2016
    ..CMTM family has a significant clinical value in diagnosis and treatment to the diseases linking to tumor and immune system. ..
  4. ncbi Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation
    Wenling Han
    Center for Human Disease Genomics, Peking University, 38 Xueyuan Road, Beijing 100083, China
    Genomics 81:609-17. 2003
    ..experimental validation identified eight novel genes designated chemokine-like factor superfamily members 1-8 (CKLFSF1-8). CKLFSF1-8 form gene clusters; the sequence identities between CKLF2 and CKLFSF1-8 are from 12.5 to 39.7%...
  5. ncbi Predicting polymerase II core promoters by cooperating transcription factor binding sites in eukaryotic genes
    Xiao Tu Ma
    School of Mathematical Sciences, Peking University and Center for Theoretical Biology, Beijing, China
    Acta Biochim Biophys Sin (Shanghai) 36:250-8. 2004
    ..The core promoter region of a newly discovered gene CKLFSF1 is predicted to locate more than 1...
  6. ncbi Last intron of the chemokine-like factor gene contains a putative promoter for the downstream CKLF super family member 1 gene
    Mingxu Xu
    Laboratory of Medical Immunology, School of Basic Medical Science, Peking University, 38 Xueyuan Road, Beijing 100083, PR China
    Biochem Biophys Res Commun 313:135-41. 2004
    The genes for chemokine-like factor (CKLF) and four chemokine-like factor super family members (CKLFSF1-4) are tightly linked on chromosome 16, with only 325 bp separating CKLF and CKLFSF1...
  7. ncbi Molecular cloning and characterization of chemokine-like factor super family member 1 (CKLFSF1), a novel human gene with at least 23 alternative splicing isoforms in testis tissue
    Lu Wang
    Peking University Center for Human Disease Genomics, 38 Xueyuan Road, Beijing 100083, China
    Int J Biochem Cell Biol 36:1492-501. 2004
    ..with experimental validation, we identified a novel gene designated chemokine-like factor super family member 1 (CKLFSF1). CKLFSF1 maps on chromosome 16q22, and the full-length gene comprises of seven exons and six introns...
  8. ncbi A functional promoter region of the CKLFSF2 gene is located in the last intron/exon region of the upstream CKLFSF1 gene
    Mingxu Xu
    Laboratory of Medical Immunology, School of Basic Medical Science, Peking University, Beijing 100083, China
    Int J Biochem Cell Biol 37:1296-307. 2005
    The genes for CKLFSF1 (chemokine-like factor super family member 1) and CKLFSF2 (chemokine-like factor super family member 2) are very closely linked, within 312 bp of each other...
  9. ncbi CKLFSF2 is highly expressed in testis and can be secreted into the seminiferous tubules
    Shuang Shi
    Laboratory of Medical Immunology, School of Basic Medical Science, Peking University, 38 Xueyuan Road, Beijing 100083, China
    Int J Biochem Cell Biol 37:1633-40. 2005
    CKLFSF2 is a member of the chemokine-like factor superfamily (CKLFSF), a novel gene family containing CKLF and CKLFSF1-8...
  10. ncbi Molecular cloning and identification of mouse Cklfsf2a and Cklfsf2b, two homologues of human CKLFSF2
    Ting Li
    Peking University Center for Human Disease Genomics, 38 Xueyuan Road, Beijing 100083, China
    Int J Biochem Cell Biol 38:420-9. 2006
    Human chemokine-like factor superfamily (CKLFSF) is a novel gene family comprising CKLF and CKLFSF1-8. Among them, CKLFSF2 is highly expressed in testis and may play important roles in male reproduction...
  11. ncbi Characterization and expression profile of CMTM3/CKLFSF3
    Ji Zhong
    Peking University Center for Human Disease Genomics, 38 Xueyuan Road, Beijing 100083, China
    J Biochem Mol Biol 39:537-45. 2006
    ..In humans, these proteins are encoded by nine genes, CKLF and CMTM1-8/CKLFSF1-8. Here we report the characteristics and expression profile of CMTM3/CKLFSF3...
  12. ncbi [CMTM1-v17, a new potential corepressor of androgen receptor]
    Bing Mei Zhu
    Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing 100083, China
    Beijing Da Xue Xue Bao 39:388-93. 2007
    ..To analyze the expression of CMTM1-v17 in normal prostate tissue and prostate carcinoma originated cell lines, and study its impact on the transactivation of androgen receptor and the possible mechanism...
  13. doi Identification and characterization of CMTM4, a novel gene with inhibitory effects on HeLa cell growth through Inducing G2/M phase accumulation
    Markus Plate
    Center for Human Disease Genomics, Department of Immunology, School of Basic Medical Science, Health Science Center, Peking University, Beijing, 100191, China
    Mol Cells 29:355-61. 2010
    ..Overexpression of CMTM4-v1 and -v2 can inhibit HeLa cell growth via G2/M phase accumulation without inducing apoptosis. Therefore, CMTM4 might be an important gene involved in cell growth and cell cycle regulation...