C11orf74

Summary

Gene Symbol: C11orf74
Description: chromosome 11 open reading frame 74
Alias: HEPIS, NWC, uncharacterized protein C11orf74
Species: human

Top Publications

  1. ncbi Identification of a third evolutionarily conserved gene within the RAG locus and its RAG1-dependent and -independent regulation
    Malgorzata Cebrat
    Department of Tumor Immunology, Laboratory of Transgenesis and Lymphocyte Biology, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland
    Eur J Immunol 35:2230-8. 2005
  2. pmc Search for the Function of NWC, Third Gene Within RAG Locus: Generation and Characterization of NWC-Deficient Mice
    Monika Kasztura
    Laboratory of Molecular and Cellular Immunology, Department of Tumor Immunology, L Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland
    Arch Immunol Ther Exp (Warsz) 64:311-9. 2016
  3. ncbi The interaction of the SARS coronavirus non-structural protein 10 with the cellular oxido-reductase system causes an extensive cytopathic effect
    Qihan Li
    Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming 650118, PR China
    J Clin Virol 34:133-9. 2005
  4. doi Identification of a novel transcriptional repressor (HEPIS) that interacts with nsp-10 of SARS coronavirus
    Min Hong
    Institute of Medical Biology, Chinese Academy of Medicine Science, Peking Union Medical College, Kunming, China
    Viral Immunol 21:153-62. 2008
  5. pmc Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk
    Hongmei Nan
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Hum Mol Genet 20:2673-9. 2011

Scientific Experts

  • Qihan Li
  • Malgorzata Cebrat
  • Monika Kasztura
  • Hongmei Nan
  • Arkadiusz Miazek
  • Pawel Kisielow
  • Min Hong
  • Karolina Peczek
  • Violetta Kapusniak
  • Agnieszka Laszkiewicz
  • Sylwia Janik
  • Michal Majkowski
  • Lukasz Sniezewski
  • Kamil Kobak
  • Frank B Hu
  • Mingfeng Zhang
  • Gary Curhan
  • Jeffrey E Lee
  • Constance Chen
  • Mousheng Xu
  • Qun Guo
  • Eric B Rimm
  • Qingyi Wei
  • Yiqing Song
  • Abrar A Qureshi
  • Christopher I Amos
  • Peter Kraft
  • Jiali Han
  • Li E Wang
  • Jiangwen Zhang
  • David J Hunter
  • Hongling Zhao
  • Weizhong Li
  • Longding Liu
  • Lichun Wang
  • Li Jiang

Detail Information

Publications5

  1. ncbi Identification of a third evolutionarily conserved gene within the RAG locus and its RAG1-dependent and -independent regulation
    Malgorzata Cebrat
    Department of Tumor Immunology, Laboratory of Transgenesis and Lymphocyte Biology, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland
    Eur J Immunol 35:2230-8. 2005
    ..The mechanisms regulating RAG expression and repression are not clear. Here we identify NWC, a third evolutionarily conserved gene within the RAG locus, and show that it is ubiquitously expressed, with the ..
  2. pmc Search for the Function of NWC, Third Gene Within RAG Locus: Generation and Characterization of NWC-Deficient Mice
    Monika Kasztura
    Laboratory of Molecular and Cellular Immunology, Department of Tumor Immunology, L Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland
    Arch Immunol Ther Exp (Warsz) 64:311-9. 2016
    b>NWC is a third gene within recombination activating gene (RAG) locus, which unlike RAG genes is ubiquitously expressed and encodes a unique protein containing three strongly evolutionarily conserved domains not found in any other known ..
  3. ncbi The interaction of the SARS coronavirus non-structural protein 10 with the cellular oxido-reductase system causes an extensive cytopathic effect
    Qihan Li
    Institute of Medical Biology, Chinese Academy of Medical Sciences, Peking Union Medical College, Kunming 650118, PR China
    J Clin Virol 34:133-9. 2005
    ..The cytopathic effect of the Coronavirus 229E strain appeared more extensive in these cells than in the control cells...
  4. doi Identification of a novel transcriptional repressor (HEPIS) that interacts with nsp-10 of SARS coronavirus
    Min Hong
    Institute of Medical Biology, Chinese Academy of Medicine Science, Peking Union Medical College, Kunming, China
    Viral Immunol 21:153-62. 2008
    ..The protein was named human embryo lung cellular protein interacting with SARS-CoV nsp-10 (HEPIS), and it is composed of 147 amino acids with several CK II phosphorylation sites...
  5. pmc Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk
    Hongmei Nan
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Hum Mol Genet 20:2673-9. 2011
    ..5 × 10(-6)) and in primary melanoma (P = 4.6 × 10(-4)) compared with the normal skin...