AMACR

Summary

Gene Symbol: AMACR
Description: alpha-methylacyl-CoA racemase
Alias: AMACRD, CBAS4, P504S, RACE, alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase
Species: human

Top Publications

  1. ncbi [A case of leptospirosis infected in Borneo Island, Malaysia]
    M Sakamoto
    Department of Infectious Diseases, Yokohama Municipal Citizen's Hospital
    Kansenshogaku Zasshi 75:1057-61. 2001
  2. ncbi Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109 0618, USA
    Prostate 67:1507-13. 2007
  3. doi Usefulness of cytokeratin 5/6 and AMACR applied as double sequential immunostains for diagnostic assessment of problematic prostate specimens
    Kiril Trpkov
    Anatomical Pathology, Rockyview General Hospital, Department of Pathology and Laboratory Medicine, Calgary Laboratory Services and University of Calgary, 7007 14 Street SW, Calgary, Alberta T2V 1P9, Canada
    Am J Clin Pathol 132:211-20; quiz 307. 2009
  4. ncbi Is there a role for prostate tumour overexpressed-1 in the diagnosis of HGPIN and of prostatic adenocarcinoma? A comparison with alpha-methylacyl CoA racemase
    M Scarpelli
    Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy
    Int J Immunopathol Pharmacol 25:67-74. 2012
  5. ncbi Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
    S Ferdinandusse
    Department of Clinical Chemistry, Emma Children s Hospital, Academic Medical Center, University of Amsterdam, The Netherlands
    Nat Genet 24:188-91. 2000
  6. ncbi alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer
    Mark A Rubin
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109 0602, USA
    JAMA 287:1662-70. 2002
  7. ncbi Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer
    Jun Luo
    Department of Pathology, Brady Urological Institute, Johns Hopkins University, School of Medicine, Baltimore, MD 21287, USA
    Cancer Res 62:2220-6. 2002
  8. ncbi Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions
    Ming Zhou
    Department of Pathology, University of Michigan School of Medicine, Ann Arbor, USA
    Am J Surg Pathol 26:926-31. 2002
  9. pmc alpha-Methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation
    Rainer Kuefer
    Department of Pathology, University of Michigan Medical School, Ann Arbor 48109 0602, USA
    Am J Pathol 161:841-8. 2002
  10. ncbi Alpha-methylacyl-CoA racemase (P504S) expression in evolving carcinomas within benign prostatic hyperplasia and in cancers of the transition zone
    Irwin Leav
    Department of Pathology, Division of Urology, University of Massachusetts Medical School, Worcester, MA, USA
    Hum Pathol 34:228-33. 2003

Research Grants

  1. DNA methylation in aging, race and prostate cancer
    Rajvir Dahiya; Fiscal Year: 2006
  2. LAURA L LOEHR; Fiscal Year: 2016
  3. Daniel Woo; Fiscal Year: 2014
  4. Jane C Figueiredo; Fiscal Year: 2015
  5. Susan Kay Murphy; Fiscal Year: 2014
  6. Linda A Teplin; Fiscal Year: 2014
  7. Kamyar Kalantar-Zadeh; Fiscal Year: 2016
  8. Drug Use, Disorder & HIV/AIDS Risk in Juvenile Justice Youth:A Longitudinal Study
    Linda A Teplin; Fiscal Year: 2010
  9. Examining the Dynamic Relationship between Motor Competence and Physical Activity
    JACQUELINE DAWN GOODWAY; Fiscal Year: 2010
  10. Annette M Langer-Gould; Fiscal Year: 2015

Detail Information

Publications412 found, 100 shown here

  1. ncbi [A case of leptospirosis infected in Borneo Island, Malaysia]
    M Sakamoto
    Department of Infectious Diseases, Yokohama Municipal Citizen's Hospital
    Kansenshogaku Zasshi 75:1057-61. 2001
    ..The case is 25-year-old male who had participated in the EcoChallenge Sabah 2000 Expedition Race, a multisport event held during August 20 to September 3, 2000 at various sites in Sabah in Malaysian Borneo...
  2. ncbi Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109 0618, USA
    Prostate 67:1507-13. 2007
    Expression of the alpha-methylacyl-CoA racemase (AMACR) gene has been established as a sensitive and specific biomarker for the diagnosis of prostate cancer...
  3. doi Usefulness of cytokeratin 5/6 and AMACR applied as double sequential immunostains for diagnostic assessment of problematic prostate specimens
    Kiril Trpkov
    Anatomical Pathology, Rockyview General Hospital, Department of Pathology and Laboratory Medicine, Calgary Laboratory Services and University of Calgary, 7007 14 Street SW, Calgary, Alberta T2V 1P9, Canada
    Am J Clin Pathol 132:211-20; quiz 307. 2009
    ..of double immunohistochemical staining for cytokeratin (CK)5/6 and alpha-methylacyl coenzyme A racemase (AMACR) applied sequentially on 1 slide by assessing 223 foci in 110 consecutive prostate specimens...
  4. ncbi Is there a role for prostate tumour overexpressed-1 in the diagnosis of HGPIN and of prostatic adenocarcinoma? A comparison with alpha-methylacyl CoA racemase
    M Scarpelli
    Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy
    Int J Immunopathol Pharmacol 25:67-74. 2012
    ..Alpha-Methyl-CoA racemase (AMACR) mRNA was identified as being overexpressed in PCa...
  5. ncbi Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
    S Ferdinandusse
    Department of Clinical Chemistry, Emma Children s Hospital, Academic Medical Center, University of Amsterdam, The Netherlands
    Nat Genet 24:188-91. 2000
    ..In all three patients we discovered a deficiency of alpha-methylacyl-CoA racemase (AMACR)...
  6. ncbi alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer
    Mark A Rubin
    Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109 0602, USA
    JAMA 287:1662-70. 2002
    ..Molecular profiling of prostate cancer has led to the identification of candidate biomarkers and regulatory genes. Discoveries from these genome-scale approaches may have applicability in the analysis of diagnostic prostate specimens...
  7. ncbi Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer
    Jun Luo
    Department of Pathology, Brady Urological Institute, Johns Hopkins University, School of Medicine, Baltimore, MD 21287, USA
    Cancer Res 62:2220-6. 2002
    ..In this study, we describe a gene, alpha-methylacyl-CoA racemase (AMACR), whose expression is consistently up-regulated in prostate cancer...
  8. ncbi Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions
    Ming Zhou
    Department of Pathology, University of Michigan School of Medicine, Ann Arbor, USA
    Am J Surg Pathol 26:926-31. 2002
    alpha-Methylacyl-CoA racemase (AMACR) is a mitochondrial and peroxisomal enzyme involved in the metabolism of branched-chain fatty acid and bile acid intermediates...
  9. pmc alpha-Methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation
    Rainer Kuefer
    Department of Pathology, University of Michigan Medical School, Ann Arbor 48109 0602, USA
    Am J Pathol 161:841-8. 2002
    alpha-Methylacyl-CoA racemase (AMACR) has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa)...
  10. ncbi Alpha-methylacyl-CoA racemase (P504S) expression in evolving carcinomas within benign prostatic hyperplasia and in cancers of the transition zone
    Irwin Leav
    Department of Pathology, Division of Urology, University of Massachusetts Medical School, Worcester, MA, USA
    Hum Pathol 34:228-33. 2003
    ..TZ, we used a highly specific rabbit monoclonal antibody (P504S) directed against alpha-methylacyl-CoA racemase (AMACR) to study the expression of the enzyme in 25 cases of evolving and fully developed carcinomas of this zone...
  11. ncbi Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer
    Shan Zha
    Brady Urological Institute, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Baltimore, MD 21287, USA
    Cancer Res 63:7365-76. 2003
    Alpha-methylacyl-CoA racemase (AMACR) is an enzyme involved in beta-oxidation of branched-chain fatty acids and bile acid intermediates. Recent work has identified AMACR as a new diagnostic marker for prostate cancer (PCa)...
  12. ncbi Alpha-methylacyl-CoA racemase: a multi-institutional study of a new prostate cancer marker
    Z Jiang
    University of Massachusetts Medical School, Worcester, MA, USA
    Histopathology 45:218-25. 2004
    To test whether alpha-methylacyl-CoA racemase (AMACR) is a sensitive and specific marker of prostate cancer.
  13. ncbi Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death
    Mark A Rubin
    Department of Pathology Amory 3 195, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:1424-32. 2005
    Alpha-methylacyl CoA racemase (AMACR) is overexpressed in prostate cancer relative to benign prostatic tissue. AMACR expression is highest in localized prostate cancer and decreases in metastatic prostate cancer...
  14. ncbi Polymorphic variants in alpha-methylacyl-CoA racemase and prostate cancer
    Sarah E Daugherty
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Prostate 67:1487-97. 2007
    Alpha-methylacyl-CoA racemase (AMACR), which prepares branched chain fatty acids to be metabolized for energy and is implicated in the activation of the COX-inhibiting form of ibuprofen, is overexpressed in prostate cancer and its ..
  15. doi Alpha-methylacyl-CoA racemase--an 'obscure' metabolic enzyme takes centre stage
    Matthew D Lloyd
    Department of Pharmacy and Pharmacology, Medicinal Chemistry, University of Bath, Claverton Down, Bath, UK
    FEBS J 275:1089-102. 2008
    ..A central role in all the metabolic pathways is played by alpha-methylacyl-CoA racemase (AMACR), which regulates metabolism of these lipids and drugs...
  16. doi Sequence variants of alpha-methylacyl-CoA racemase are associated with prostate cancer risk: a replication study in an ethnically homogeneous population
    Liesel M FitzGerald
    Menzies Research Institute, University of Tasmania, Hobart, Australia
    Prostate 68:1373-9. 2008
    Examination of variants of the alpha-methylacyl-CoA racemase (AMACR) gene, as genetic contributors to prostate cancer risk, has been of considerable interest given the gene's recently established role as a diagnostic biomarker for ..
  17. pmc Significance of overexpression of alpha methylacyl-coenzyme A racemase in hepatocellular carcinoma
    Wei Li
    Department of Pathology, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    J Exp Clin Cancer Res 27:2. 2008
    alpha-Methylacyl-CoA racemase (AMACR), an immunomarker for prostatic adenocarcinoma, has been shown to be expressed in a variety of other neoplasms...
  18. pmc Deletion hotspots in AMACR promoter CpG island are cis-regulatory elements controlling the gene expression in the colon
    Xiang Zhang
    Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    PLoS Genet 5:e1000334. 2009
    Alpha-methylacyl-coenzyme A racemase (AMACR) regulates peroxisomal beta-oxidation of phytol-derived, branched-chain fatty acids from red meat and dairy products -- suspected risk factors for colon carcinoma (CCa)...
  19. pmc AMACR polymorphisms, dietary intake of red meat and dairy and prostate cancer risk
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Prostate 71:498-506. 2011
    Alpha-methylacyl CoA racemase (AMACR) is an enzyme involved in fatty acids metabolism...
  20. pmc High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S)
    Brice A P Wilson
    Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Mol Cancer Ther 10:825-38. 2011
    methylacyl coenzyme A racemase (AMACR) is a metabolic enzyme whose overexpression has been shown to be a diagnostic indicator of prostatic adenocarcinoma and other solid tumors...
  21. doi Overexpression of α-methylacyl-CoA racemase is associated with CTNNB1 mutations in hepatocellular carcinomas
    Shigeki Sekine
    Pathology Division, National Cancer Centre Research Institute, Tokyo, Japan
    Histopathology 58:712-9. 2011
    Methylacyl-CoA racemase (AMACR) is expressed in the majority of hepatocellular carcinomas (HCCs) at variable levels, but the significance of AMACR overexpression remains elusive...
  22. ncbi Sequence variants of alpha-methylacyl-CoA racemase are associated with prostate cancer risk
    Siqun L Zheng
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Cancer Res 62:6485-8. 2002
    The enzyme alpha-methylacyl-CoA racemase (AMACR) plays an important role in peroxisomal beta-oxidation of branched-chain fatty acid and therefore is relevant to carcinogenesis...
  23. ncbi A variant of the alpha-methyl-acyl-CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer
    James N Mubiru
    Department of Pathology, The University of Texas Health Science Center, San Antonio, 78229, USA
    Prostate 65:117-23. 2005
    Alpha-methylacyl-CoA racemase (AMACR) is a mitochondrial and peroxisomal enzyme that is overexpressed in prostate cancer...
  24. ncbi Alpha-methylacyl-CoA racemase protein expression is associated with the degree of differentiation in breast cancer using quantitative image analysis
    Agnieszka K Witkiewicz
    Department of Pathology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Cancer Epidemiol Biomarkers Prev 14:1418-23. 2005
    Alpha-methylacyl-CoA racemase (AMACR) is an enzyme involved in the metabolism of fatty acids and is an important tissue biomarker in the prostate to distinguish normal glands from prostate cancer...
  25. ncbi Alpha-methylacyl-CoA racemase/P504S overexpression in colorectal carcinoma is correlated with tumor differentiation
    Xueying Shi
    Department of Pathology, School of Basic Medical Sciences, Peking University, Beijing, China
    Appl Immunohistochem Mol Morphol 15:175-80. 2007
    Alpha-methylacyl-CoA racemase (AMACR)/P504S is an enzyme involved in the metabolism of branched-chain fatty acids. Little is known about correlation of AMACR expression with colorectal carcinoma (CRC) differentiation and prognosis...
  26. ncbi Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma
    Sarah E Daugherty
    Divison of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, 6120 Executive Boulevard, EPS Rm 8113, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1536-42. 2007
    alpha-Methylacyl-CoA racemase (AMACR), an enzyme involved in oxidation of branched chain fatty acids and cholesterol metabolites, as well as ibuprofen metabolism, is overexpressed in colorectal adenomas and cancer...
  27. doi AMACR expression in colorectal cancer is associated with left-sided tumor localization
    Andreas Marx
    Institute for Pathology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246 Hamburg, Germany
    Virchows Arch 453:243-8. 2008
    Alpha-methylacyl-CoA racemase (AMACR) is an enzyme playing an important role in the beta-oxidation of branched-chain fatty acids and fatty acid derivatives...
  28. ncbi a-Methylacyl coenzyme A racemase is highly expressed in the intestinal-type adenocarcinoma and high-grade dysplasia lesions of the stomach
    Wenbin Huang
    Department of Pathology, Nanjing Medical College Affiliated Nanjing First Hospital, Nanjing Jiangsu, P R China
    Histol Histopathol 23:1315-20. 2008
    To study a-Methylacyl coenzyme A racemase (AMACR) expression in gastric intestinal-type adenocarcinoma and its precursors, we performed an immunohistochemical assay (using an avidin-biotin-peroxidase complex method) on 106 paraffin-..
  29. doi Combined alpha-methylacyl coenzyme A racemase/p53 analysis to identify dysplasia in inflammatory bowel disease
    Andreas Marx
    Institute of Pathology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany
    Hum Pathol 40:166-73. 2009
    ..It is concluded that combined alpha-methylacyl coenzyme A racemase/p53 analysis may represent a helpful tool to confirm dysplasia in inflammatory bowel disease...
  30. pmc Design, characteristics, and usefulness of state-based behavioral risk factor surveillance: 1981-87
    P L Remington
    Division of Nutrition, Centers for Disease Control (CDC, Atlanta, GA 30333
    Public Health Rep 103:366-75. 1988
    ..The raw data were weighted to the age, race, and sex distribution for each State from the 1980 census data...
  31. ncbi Correlates of daytime sleepiness in 4578 elderly persons: the Cardiovascular Health Study
    C W Whitney
    Department of Biostatistics, University of Washington, Seattle, USA
    Sleep 21:27-36. 1998
    ..Although elderly black men were less likely to report frequent awakenings than those in the other three race and gender groups, they had significantly higher mean ESS scores...
  32. ncbi Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features
    W Demark-Wahnefried
    Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina, USA
    Urology 58:47-52. 2001
    ..The tumors of diet-treated patients were compared with those of historic cases (matched by age, race, prostate-specific antigen level at diagnosis, and biopsy Gleason sum) with respect to apoptosis (terminal ..
  33. ncbi Race, resource use, and survival in seriously ill hospitalized adults. The SUPPORT Investigators
    R S Phillips
    Division of General Medicine and Primary Care, Beth Israel Hospital, Boston, Mass 02215, USA
    J Gen Intern Med 11:387-96. 1996
    OBJECTIVE: To examine the association between patient race and hospital resource use. DESIGN: Prospective cohort study. SETTING: Five geographically diverse teaching hospitals...
  34. pmc The status of community water fluoridation in the United States
    M W Easley
    Department of Comprehensive Dentistry, University of Detroit, School of Dentistry
    Public Health Rep 105:348-53. 1990
    ..and efficiency of community water fluoridation in preventing dental caries for Americans regardless of age, race, ethnicity, religion, educational status, or socioeconomic level...
  35. ncbi Recurrent or new injury outcomes after return to work in chronic disabling spinal disorders. Tertiary prevention efficacy of functional restoration treatment
    P Garcy
    PRIDE Research Foundation, Dallas, Texas, USA
    Spine (Phila Pa 1976) 21:952-9. 1996
    ..3% (n = 64) of treated patients with a new injury claim in the ensuing 12 months was matched for gender, age, race, length of disability, workers' compensation venue, previous surgery, and litigation status to an identically sized ..
  36. pmc Clinical and echocardiographic correlates of health status in patients with acute chest pain
    K E Fleischmann
    Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Mass, USA
    J Gen Intern Med 12:751-6. 1997
    ..For the SF-36 score at 1 year, age, male gender, white race, the presence of rales, and a comorbidity score were independently predictors in multivariate analysis; ..
  37. ncbi Trichomonas vaginalis associated with low birth weight and preterm delivery. The Vaginal Infections and Prematurity Study Group
    M F Cotch
    National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA
    Sex Transm Dis 24:353-60. 1997
    ..RESULTS: The prevalence of T. vaginalis infection at enrollment was 12.6%. Race-specific prevalence rates were 22.8% for black, 6.6% for Hispanic, and 6.1% for white women...
  38. ncbi Plasma renin activity and insulin resistance in African American and white children: the Bogalusa Heart Study
    W Chen
    Tulane Center for Cardiovascular Health, School of Public Health and Tropical Medicine, Tulane University Medical Center, New Orleans, Louisiana 70112, USA
    Am J Hypertens 14:212-7. 2001
    ..Children were selected using a stratified random sampling procedure based on race-, age-, and sex-specific percentiles of diastolic blood pressure...
  39. pmc Birth weight, maternal age, and education: new observations from Connecticut and Virginia
    A Shmueli
    The Joseph H. and Belle R. Braun Hebrew University, Hadassah School of Public Health and Community Medicine, Jerusalem, Israel
    Yale J Biol Med 72:245-58. 1999
    ..about the mechanism(s) for this effect, as well as the interactions between these factors, maternal age, and race. Presented here is the analysis of a large, recent sample of over 20,000 consecutive live births in 12 hospitals, ..
  40. pmc Prevalence of illicit drugs detected in the urine of women of childbearing age in Alabama public health clinics
    D A Pegues
    Division of Field Epidemiology, Centers for Disease Control and Prevention (CDC, Atlanta, GA
    Public Health Rep 109:530-8. 1994
    ..associated with a higher prevalence of positive results for any drug tested or for marijuana included white race, older age, being divorced, non student occupation, having 12 or less years of education, attending a clinic ..
  41. ncbi Risk indicators of edentulism, partial tooth loss and prosthetic status among black and white middle-aged and older adults
    T A Dolan
    Division of Public Health Services and Research, University of Florida College of Dentistry, Gainesville, FL, USA
    Community Dent Oral Epidemiol 29:329-40. 2001
    ..and periodontal status, dental fillings, dental attitudes and financial resources, a residual association with race suggests that blacks are much less likely to receive prosthetic crowns...
  42. ncbi Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. The Vaginal Infections and Prematurity Study Group
    S L Hillier
    University of Washington, Seattle, USA
    N Engl J Med 333:1737-42. 1995
    ..7; 1.3 to 2.2), primigravidity (odds ratio, 1.6; 1.1 to 1.9), smoking (odds ratio, 1.4; 1.1 to 1.7); and black race (odds ratio, 1.4; 1.1 to 1.7)...
  43. pmc Breast-feeding, nutritional status, and other prognostic factors for dehydration among young children with diarrhoea in Brazil
    C G Victora
    Department of Social Medicine, Universidade Federal de Pelotas, RS, Brazil
    Bull World Health Organ 70:467-75. 1992
    ..the home; low paternal education level; young age; maternal age 25-29 years or less than 20 years; mother of mixed race; high birth order; short birth interval; low birth weight; stunting, underweight and wasting; lack of breast-..
  44. ncbi Socioeconomic outcomes of combined spine surgery and functional restoration in workers' compensation spinal disorders with matched controls
    T Mayer
    Department of Orthopedic Surgery, University of Texas Southwestern Medical Center, Dallas, USA
    Spine (Phila Pa 1976) 23:598-605; discussion 606. 1998
    ..and control/fusion, selected from the same cohort of patients with chronic spinal disorders based on age, gender, race, length of disability, and workers' compensation jurisdiction...
  45. pmc Do race and gender influence the use of invasive procedures?
    R E Watson
    College of Human Medicine, Michigan State University, East Lansing, MI 48824 1315, USA
    J Gen Intern Med 16:227-34. 2001
    To assess the influence of race and gender influence on the use of invasive procedures in patients with acute myocardial infarction (AMI) in community hospitals.
  46. pmc Defining quality of care indicators for neonatal intensive care units independent of maternal risk factors
    I Ekelem
    Department of Pediatrics, King Drew Medical Center, Los Angeles, Calif 90059
    J Natl Med Assoc 82:345-50. 1990
    ..Even when neonatal mortality rate is corrected for four risk factors, race, sex, birthweight, and multiple births, (California Data Research Facility, Santa Barbara, CA) it is possible that ..
  47. ncbi Does scoliosis have a psychological impact and does gender make a difference?
    W K Payne
    Twin Cities Scoliosis Spine Center, University of Minnesota, Minneapolis, USA
    Spine (Phila Pa 1976) 22:1380-4. 1997
    ..Collected on more than 75,000 school age adolescents, with established validity and reliability, a secondary analysis of adolescents with scoliosis was performed as compared with a normative peer group...
  48. pmc Alcohol-related birth defects: an update
    K R Warren
    Office of Scientific Affairs, National Institute on Alcohol Abuse and Alcoholism, Rockville, MD 20852
    Public Health Rep 103:638-42. 1988
    ..Factors such as race, beer drinking, maternal weight gain, and low socioeconomic status are associated with a statistical increase in ..
  49. ncbi Temporal relation between blood pressure and serum creatinine in young adults from a biracial community: the Bogalusa Heart Study
    A A Youssef
    Tulane Center for Cardiovascular Health and Department of Epidemiology, Tulane University Medical Center, New Orleans, Louisiana, USA
    Am J Hypertens 13:770-5. 2000
    ..000) and diastolic (P = .001) blood pressure at baseline, but not the other way around. Other race and sex groups did not show such significant temporal relations...
  50. pmc Late middle-aged and older men living with HIV/AIDS: race differences in coping, social support, and psychological distress
    T G Heckman
    Center for AIDS Intervention Research, Athens, USA
    J Natl Med Assoc 92:436-44. 2000
    ..combined older African-American and white participants into one large sample, thereby neglecting potential race differences...
  51. pmc Survival after in-hospital cardiopulmonary resuscitation. A meta-analysis
    M H Ebell
    Department of Family Practice, Michigan State University, East Lansing, Mich 48824-1315, USA
    J Gen Intern Med 13:805-16. 1998
    ..9, 515), metastatic cancer (OR 3.9; 95% CI 1.2, 12. 6), dementia (OR 3.1; 95% CI 1.1, 8.8), African-American race (OR 2. 8; 95% CI 1.4, 5.6), serum creatinine level at a cutpoint of 1.5 mg/dL (OR 2.2; 95% CI 1.2, 3...
  52. pmc Predictors of infant mortality among college-educated black and white women, Davidson County, Tennessee, 1990-1994
    A O Scott Wright
    Department of Family and Preventive Medicine, Meharry Medical College, Nashville, Tennessee, USA
    J Natl Med Assoc 90:477-83. 1998
    ..The following variables entered the logistic model process: maternal and paternal age; race and education; nativity status; maternal risk factors; interpregnancy interval; parity; infant gender; tobacco or ..
  53. ncbi Impact of language barriers on patient satisfaction in an emergency department
    O Carrasquillo
    Department of Medicine, Cambridge Hospital, Mass, USA
    J Gen Intern Med 14:82-7. 1999
    ..5% of English speakers (p < .05). In multivariate analysis adjusting for hospital site, age, gender, race/ethnicity, education, income, chief complaint, urgency, insurance status, Medicaid status, ED as the patient's ..
  54. ncbi The impact of socioeconomic status on the intensity of ambulatory treatment and health outcomes after hospital discharge for adults with asthma
    J S Haas
    Division of General Medicine, Brigham and Women's Hospital
    J Gen Intern Med 9:121-6. 1994
    OBJECTIVES: To examine whether differences in intensities of care by socioeconomic status and race result in worse health among adults with asthma post-hospital discharge...
  55. ncbi Adherence to screening mammography recommendations in a university general medicine clinic
    N C Dolan
    Division of General Internal Medicine, Northwestern University Medical School, Chicago, IL 60611, USA
    J Gen Intern Med 10:299-306. 1995
    ..MEASUREMENT: Independent variables were: patient age, race, insurance type, educational level, and duration of affiliation with the practice; visit type; and health care ..
  56. pmc HIV/AIDS patients' perspectives on adhering to regimens containing protease inhibitors
    V E Stone
    Department of Medicine, Memorial Hospital of Rhode Island, Pawtucket 02860, USA
    J Gen Intern Med 13:586-93. 1998
    ..and positive impressions of PIs were prevalent among this diverse group of persons with HIV, and did not differ by race/ethnicity or gender. Most knew that these were new, potent medications for treating HIV/AIDS...
  57. pmc Preferences for sites of care among urban homeless and housed poor adults
    J L Gibbon
    Center for Research on Health Care, Division of General Internal Medicine, University of Pittsburgh, PA, USA
    J Gen Intern Med 14:599-605. 1999
    ..6-7.5), nonveteran status (RR = 1.0-2.5), being unmarried (RR = 1. 2-3.1), and white race (RR = 1.0-3.3)...
  58. pmc High prevalence of overweight and short stature among Head Start children in Massachusetts
    J L Wiecha
    Growth and Nutrition Program, Massachusetts Department of Public Health, Boston
    Public Health Rep 109:767-73. 1994
    ..21, P < 0.01). The prevalence of overweight and short stature varied by race and ethnicity...
  59. ncbi An epidemiologic study of episodes of back pain care
    P G Shekelle
    West Los Angeles VAMC, California, USA
    Spine (Phila Pa 1976) 20:1668-73. 1995
    ..There were 9.1 episodes per 100 person-years. Insurance status, geographic site, white race, lesser education, poorer physical functioning, and greater pain at base-line all were independently associated ..
  60. ncbi Sociodemographic correlates of alcohol consumption among African-American and white women
    S L Darrow
    Roswell Park Cancer Institute, Buffalo, NY 14263
    Women Health 18:35-51. 1992
    ..Discriminant function analysis was employed to investigate the relationship between alcohol consumption and race, age, church attendance, family history of alcohol problems, household density, marriage, socioeconomic status (SES)..
  61. pmc Correlates of drug abuse among homeless and transient people in the Washington, DC, metropolitan area in 1991
    E Y Lambert
    Community Research Branch, National Institute on Drug Abuse, Rockville, MD 20857, USA
    Public Health Rep 110:455-61. 1995
    ..Only past year use of cocaine differed significantly by race or ethnicity, with a greater likelihood among homeless blacks than among homeless whites...
  62. pmc Maternal factors, birthweight, and racial differences in infant mortality: a Georgia population-based study
    J F Sung
    Dept of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, GA 30310
    J Natl Med Assoc 86:437-43. 1994
    ..ratio for unmarried compared to married mothers was calculated and adjusted singly for maternal education, age and race, and infant birthweight...
  63. ncbi Racial differences in the medical treatment of elderly Medicare patients with acute myocardial infarction
    J J Allison
    Division of General Internal Medicine, University of Alabama, Birmingham School of Medicine, USA
    J Gen Intern Med 11:736-43. 1996
    ..MEASUREMENTS: We first performed a crude analysis using all cases to compare by race the use of thrombolysis, beta-adrenergic blockade, and aspirin in the setting of AMI...
  64. ncbi Trends in reporting of maternal drug abuse and infant mortality among drug-exposed infants in New York City
    L Habel
    Division of Biostatistics and Epidemiologic Research, New York City Department of Health
    Women Health 16:41-58. 1990
    ..3 per 1000 live births in 1987, with abuse of cocaine accounting for most of the rise. When standardized for race and ethnicity, the mortality rate for drug-exposed infants born from 1978 through 1986 was 35.9, or 2...
  65. ncbi Social factors and self-assessed oral health in South Africa
    L Gilbert
    Department of Sociology, University of the Witwatersrand, Johannesburg, South Africa
    Community Dent Oral Epidemiol 22:47-51. 1994
    ..of "normally" and knowledge of oral care, which are determined by social factors such as culture, class and race. The purpose of this paper is to examine self-assessed oral health in South Africa according to relevant social ..
  66. ncbi Risk variables of insulin resistance syndrome in African-American and Caucasian young adults with microalbuminuria: the Bogalusa Heart Study
    S R Srinivasan
    Tulane Center for Cardiovascular Health, Department of Epidemiology, New Orleans, Louisiana 70112, USA
    Am J Hypertens 13:1274-9. 2000
    ..Individuals with either urinary albumin to creatinine ratio at or above the 90th percentile (age, race, and gender specific) or urinary albumin level at or above 30 mg/L were considered as having slightly elevated ..
  67. ncbi Exercise blood pressure response and 5-year risk of elevated blood pressure in a cohort of young adults: the CARDIA study
    T A Manolio
    Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892
    Am J Hypertens 7:234-41. 1994
    ..001). After adjustment for age, race, sex, clinic, resting systolic pressure, body mass index, heavy activity score, exercise duration, and preexercise ..
  68. ncbi Timing of referral of terminally ill patients to an outpatient hospice
    N A Christakis
    Leonard Davis Institute of Health Economics, Department of Sociology, University of Pennsylvania, Philadelphia
    J Gen Intern Med 9:314-20. 1994
    ..outpatients was analyzed with Cox regression to evaluate the effect on length of stay of patient age, gender, race, diagnosis, activity level, mental status, dyspnea, insurance, income, religion, and home support, and of referring ..
  69. ncbi Effects of race and ethnicity on insulin sensitivity, blood pressure, and heart rate in three ethnic populations: comparative studies in African-Americans, African immigrants (Ghanaians), and white Americans using ambulatory blood pressure monitoring
    K Osei
    Department of Medicine, The Ohio State University Medical Center, Columbus 43210-1296, USA
    Am J Hypertens 9:1157-64. 1996
    ..We speculate that these chronobiological alterations in BP and HR in blacks appear to be genetically determined...
  70. ncbi Lack of independent relationships between left ventricular mass and cardiovascular reactivity to physical and psychological stress in the Coronary Artery Risk Development in Young Adults (CARDIA) Study
    J H Markovitz
    University of Alabama at Birmingham 35205, USA
    Am J Hypertens 9:915-23. 1996
    ..Analyses were stratified by gender and race. The relationships of LVM/height2...
  71. ncbi Factors predicting readmission of older general medicine patients
    R Burns
    Section of Geriatric Medicine, Veterans Affairs Medical Center, Memphis, TN 38104
    J Gen Intern Med 6:389-93. 1991
    ..Independent variables included demographic (age, race, income, education), social support (marital status, living arrangements), psychological (cognition, depression), ..
  72. ncbi Measuring social inequalities in health in the United States: a historical review, 1900-1950
    N Krieger
    Department of Health and Social Behavior, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Health Serv 26:391-418. 1996
    For over two centuries, U.S. vital statistics routinely have been stratified by age, sex, and race, but not by social class. The usual explanation is that U.S. government officials have not considered social class relevant to health...
  73. ncbi Ambulatory intraarterial blood pressure in essential hypertension. Effects of age, sex, race, and body mass--the Northwick Park Hospital Database Study
    D U Acharya
    Department of Cardiology, Northwick Park Hospital, Harrow, England
    Am J Hypertens 9:943-52. 1996
    ..blood pressure (IABP) from 723 untreated hypertensive patients were analyzed for the effects of age, sex, race, and body mass index on the level of IABP and its circadian variation...
  74. pmc Natural history of HIV-1 infection and predictors of survival in a cohort of HIV-1 seropositive injecting drug users
    L S Brown
    Division of Medical Services, Evaluation and Research, Addiction Research and Treatment Corporation, Brooklyn, New York 11201, USA
    J Natl Med Assoc 88:37-42. 1996
    ..Eighty-nine of 328 study subjects died during the 5 years of observation. Comparing African Americans and Latinos, race/ethnicity was not related to survival. Survival was related to baseline CD4 count and hemoglobin level...
  75. ncbi Characteristics of births to single- and multiple-race women: California, Hawaii, Pennsylvania, Utah, and Washington, 2003
    Brady E Hamilton
    US Department of Health and Human Services, Division of Vital Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    Natl Vital Stat Rep 55:1-20. 2007
    ..as single racial entries that mothers and fathers had reported on birth certificates in accordance with the revised race and ethnicity standards issued by the Office of Management and Budget (OMB) in 1997...
  76. ncbi Oral disadvantage among dentate adults
    G H Gilbert
    Claude D. Pepper Center for Research on Oral Health in Aging, Gainesville, FL 32610-0416, USA
    Community Dent Oral Epidemiol 25:301-13. 1997
    ..In these same regressions, differences in disadvantage due to race, poverty status, socioeconomic status, and rural/urban area of residence were not evident...
  77. pmc Racial variation in the use of do-not-resuscitate orders
    L B Shepardson
    Division of General Internal Medicine and Health Care Research, Cleveland VA Medical Center, Ohio, USA
    J Gen Intern Med 14:15-20. 1999
    ..82-0.88). Multiple logistic regression analysis was used to determine the independent association between race and use of DNR orders, adjusting for age, admission severity, and other covariates...
  78. pmc Geographic variation in cardiovascular disease mortality in US blacks and whites
    L W Pickle
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    J Natl Med Assoc 91:545-56. 1999
    ..This article describes these patterns and discusses how they vary by sex, race, age, and over time...
  79. pmc Adherence to guidelines for oral anticoagulation after venous thrombosis and pulmonary embolism
    D A Ganz
    Division of Pharmaceoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass 02115, USA
    J Gen Intern Med 15:776-81. 2000
    ..In multivariate models, African-American race was associated with an increased risk of a shorter than recommended duration of therapy (odds ratio [OR], 1...
  80. pmc Racial variation in spontaneous fetal deaths at 20 weeks or older in upstate New York, 1980-86
    G M Buck
    Department of Social and Preventive Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo 14214, USA
    Public Health Rep 110:587-92. 1995
    The distribution of spontaneous fetal deaths (at age 20 weeks or more) by maternal race has received considerably less study than other adverse pregnancy outcomes...
  81. pmc The effects of child abuse and race on risk-taking in male adolescents
    J T Hernandez
    Department of Psychiatry, University of North Carolina Chapel Hill 27599 7160
    J Natl Med Assoc 85:593-7. 1993
    ..Abuse but not race was predictive of drinking and of having serious drinking problems...
  82. pmc Race, gender, drug use, and participation in AIDS clinical trials. Lessons from a municipal hospital cohort
    V E Stone
    Section of General Internal Medicine, University School of Medicine, Boston, MA, USA
    J Gen Intern Med 12:150-7. 1997
    ..knowledge of clinical trails or reasons for not participating explain differences in participation rates by gender, race, or drug use. DESIGN: Cross-sectional survey of patients with HIV disease...
  83. pmc Breast cancer screening use by African Americans and Whites in an HMO
    L M Reisch
    Departments of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    J Gen Intern Med 15:229-34. 2000
    ..0001) and clinical breast examinations (5.35 vs 4.92; P <.01) than African-American women. However, a woman's race was no longer a statistically significant predictor of breast cancer screening after adjustment for differences in ..
  84. pmc Saliva cotinine and recent smoking--evidence for a nonlinear relationship
    G E Swan
    SRI International, Menlo Park, CA 94025
    Public Health Rep 108:779-83. 1993
    ..Several individual differences (for example, age, race, sex, and so forth) may affect cotinine excretion, and a peculiar nonlinearity between the number of cigarettes ..
  85. ncbi Does a lean prepregnancy body mass index influence outcome in pregnancies complicated by mild preeclampsia remote from term?
    J R Barton
    Department of Obstetrics and Gynecology, Central Baptist Hospital, Lexington, Kentucky, USA
    Hypertens Pregnancy 20:283-90. 2001
    ..To determine the influence of a lean prepregnancy body mass index (BMI) on pregnancy outcome in women with mild preeclampsia...
  86. ncbi Association of dental health knowledge with periodontal conditions among regular patients
    J D Bader
    Dept. of Dental Ecology, School of Dentistry, University of North Carolina, Chapel Hill
    Community Dent Oral Epidemiol 18:32-6. 1990
    ..When effects associated with age, sex, race, and different dental practices were held constant, these patient knowledge scales did not explain substantial ..
  87. ncbi Precise limitation of concerted evolution to ORFs in mosquito Hsp82 genes
    M Q Benedict
    Center for Insect Science, University of Arizonia, Tucson, 30341, USA
    Insect Mol Biol 5:73-9. 1996
    ..The two genes are in a head-to-head arrangement separated by approx. 0.9 kbp. Northern hybridizations and 5' RACE demonstrate that both genes are transcribed, have moderate levels of constitutive transcription, and are also heat-..
  88. ncbi Lessons from combination therapy in Veterans Affairs Studies. Department of Veterans Affairs Cooperative Study Group on antihypertensive agents
    B J Materson
    Cooperative Studies Program, Department of Veterans Affairs Medical Research Service, Miami, FL, USA
    Am J Hypertens 9:187S-191S. 1996
    ..the order that the drugs were administered, by estimated total response rates for the combinations, and by age and race. The order of drug administration did have an effect for some of the drug pairs...
  89. pmc Lack of gender and racial differences in surgery and mortality in hospitalized Medicare beneficiaries with bleeding peptic ulcer
    G S Cooper
    Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
    J Gen Intern Med 12:485-90. 1997
    OBJECTIVE: Determine the relation of race and gender to outcome from bleeding peptic ulcer. DESIGN: Retrospective cohort study. SETTING: All acute care hospitals in the United States...
  90. ncbi A clinic-based mammography intervention targeting inner-city women
    V Taylor
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
    J Gen Intern Med 14:104-11. 1999
    ..001). These effects persisted after adjustment for potential confounding by age, race, medical insurance coverage, and previous mammography experience at the hospital (odds ratio 3...
  91. ncbi Differential impact of recent Medicaid expansions by race and ethnicity
    A D Racine
    Albert Einstein College of Medicine, Children s Hospital at Montefiore, Bronx, New York 10461, USA
    Pediatrics 108:1135-42. 2001
    ..children's insurance coverage, use of health care services, or health status differently, depending on their race/ethnicity...
  92. pmc Discrepancies between published data on racial classification and self-reported race: evidence from the 2002 North Carolina live birth records
    Paul A Buescher
    State Center for Health Statistics, North Carolina Division of Public Health, Raleigh, NC 27699 1908, USA
    Public Health Rep 120:393-8. 2005
    We compared data on race as reported by the mother on North Carolina birth certificates with data on race in officially reported statistics...
  93. ncbi Maternal birthplace and breastfeeding initiation among term and preterm infants: a statewide assessment for Massachusetts
    Anne Merewood
    Department of Pediatrics, Boston University School of Medicine, Boston, Massachusetts, USA
    Pediatrics 118:e1048-54. 2006
    ..In addition, national surveys calculate breastfeeding rates among term infants according to maternal race/ethnicity, but maternal birthplace is not recorded...
  94. pmc Neighborhood environment, racial position, and risk of police-reported domestic violence: a contextual analysis
    Deborah N Pearlman
    Department of Community Health, Brown University, Providence, RI 02912, USA
    Public Health Rep 118:44-58. 2003
    ..of neighborhood socioeconomic conditions to risk of police-reported domestic violence in relation to victim's race. Data on race came from police forms legally mandated for the reporting of domestic violence and sexual assault.
  95. ncbi Fatal injuries among children by race and ethnicity--United States, 1999-2002
    Stephanie J Bernard
    Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention CDC, Atlanta, Georgia 30333, USA
    MMWR Surveill Summ 56:1-16. 2007
    ..The effects of age on the difference in rates between white and minority children and the mechanisms of injury that contribute most to that difference have not been previously reported...
  96. pmc Injury fatalities among young children
    L A Fingerhut
    Division of Analysis, National Center for Health Statistics, Hyattsville, MD 20782
    Public Health Rep 103:399-405. 1988
    ..The purpose of this article is to analyze race and sex differentials in injury fatalities among young children...
  97. ncbi Factors determining the rate of referral, transplantation, and survival on dialysis in women with ESRD
    J McCauley
    Department of Medicine, University of Pittsburgh School of Medicine, PA 15213, USA
    Am J Kidney Dis 30:739-48. 1997
    ..We questioned whether black women were referred at lower rates than whites and if race and other socioeconomic factors predicted referral, rate of renal transplantation, and patient survival on dialysis...
  98. ncbi United States Department of Agriculture-Agricultural Research Service studies on polyketide toxins of Fusarium oxysporum f sp vasinfectum: potential targets for disease control
    Alois A Bell
    USDA ARS SPARC, 2765 F and B Road, College Station, TX 77845, USA
    Pest Manag Sci 59:736-47. 2003
    ..f sp vasinfectum (Atk) Sny & Hans, representing five races and 20 vegetative compatibility groups within race 1 were used to determine the identity, biosynthetic regulation and taxonomic distribution of polyketide toxins ..
  99. ncbi Pedestrian fatalities by race/ethnicity in Arizona, 1990-1996
    Doug Campos-Outcalt
    Maricopa County Department of Public Health Campos Outcalt, Phoenix, Arizona 850006, USA
    Am J Prev Med 23:129-35. 2002
    To explore rates of pedestrian fatalities in Arizona, and how rates and circumstances of pedestrian deaths differ by race/ethnicity, urban or rural residence, age, and gender.
  100. ncbi The role of race and ethnicity in the State Children's Health Insurance Program (SCHIP) in four states: are there baseline disparities, and what do they mean for SCHIP?
    Laura P Shone
    Strong Children s Research Center, Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Pediatrics 112:e521. 2003
    ..To determine the potential impact of SCHIP on racial and ethnic disparities, it is critical to assess baseline levels of health disparities among children enrolling in SCHIP...
  101. ncbi Cancer mortality in the United States by education level and race
    Jessica D Albano
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Rd, Atlanta, GA 30329, USA
    J Natl Cancer Inst 99:1384-94. 2007
    Although both race and socioeconomic status are well known to influence mortality patterns in the United States, few studies have examined the simultaneous influence of these factors on cancer incidence and mortality...

Research Grants87

  1. DNA methylation in aging, race and prostate cancer
    Rajvir Dahiya; Fiscal Year: 2006
    ..goal of this proposal is to identify and characterize the epigenetic alterations that are involved in aging and race-related prostate cancer...
  2. LAURA L LOEHR; Fiscal Year: 2016
    ..that this paradox of unexpected low rates of AF in African Americans may be due to differential detection of AF by race (ascertainment bias)...
  3. Daniel Woo; Fiscal Year: 2014
    ..1000 cases of ICH among blacks, 1000 cases of ICH among Hispanics, and 3000 controls matched to the cases by race/ethnicity, age (5 years), gender and geographic location...
  4. Jane C Figueiredo; Fiscal Year: 2015
    ..We will also examine heterogeneity of the risk estimates by ethnicity/race by leveraging GWA data on NH-Whites (2,142 cases, 1,909 controls, U01 CA122839, Casey), (4,000 cases, 6,000 NH-..
  5. Susan Kay Murphy; Fiscal Year: 2014
    ..imprint deregulation, and thus, further hypothesize that higher risk in African Americans and Hispanics is due to race/ethnic differences in deregulation of these genes...
  6. Linda A Teplin; Fiscal Year: 2014
    ..10-18 years (1172 males, 657 females;1005 African Americans, 296 non-Hispanic whites, 524 Hispanics, and 4 "other" race/ethnicity)...
  7. Kamyar Kalantar-Zadeh; Fiscal Year: 2016
    ..disparities are due to distinct pathophysiologic mechanisms related to nutritional status and dietary intake across race;whereas 2 alternative hypotheses related to bone-and-mineral disorders and psychosocial and coping status will also ..
  8. Drug Use, Disorder & HIV/AIDS Risk in Juvenile Justice Youth:A Longitudinal Study
    Linda A Teplin; Fiscal Year: 2010
    ..diverse sample (n=758;330 females, 428 males;412 African Americans, 137 non-Hispanic whites, 207 Hispanics, 2 other race/ethnicity) of persons who were arrested and detained in Cook County (Chicago) Illinois, aged 10-18 years at ..
  9. Examining the Dynamic Relationship between Motor Competence and Physical Activity
    JACQUELINE DAWN GOODWAY; Fiscal Year: 2010
    ..Specifically, the relationships will strengthen across the three age groups tested. A 3 (Age) X 3 (Ethnicity/Race) X 2 (Gender) cross-sectional design will examine the relationship among the four variables in the conceptual model ..
  10. Annette M Langer-Gould; Fiscal Year: 2015
    ..However, the role of vitamin D in MS risk likely varies by race/ethnicity and genetic background...
  11. Susan L Zickmund; Fiscal Year: 2015
    ..To examine the associations between patient race/ethnicity and satisfaction with overall, outpatient, inpatient, and 12 domains of VA health care based on a ..
  12. Perfluoroalkyl chemicals and the risk of developing clinical and subclinical CVD
    Anoop Shankar; Fiscal Year: 2012
    ..this contemporary general population sample and examine if the association between PFCs and CVD vary by gender, or race/ethnicity...
  13. JOSEPH LEO WIEMELS; Fiscal Year: 2014
    ..an algorithm to predict birth weight based on factors such as gestational age, gender, birth order, parental race, parental Hispanic status, and parental ages, and calculate a proportion of expected birth weight (PEBW) for all ..
  14. Effects of Disadvantage and Protective Resources on Alcohol-related Disparities
    Sarah Zemore; Fiscal Year: 2013
    ..At present, however, there is a critical gap in our understanding of alcohol disparities related to race. Prior research has already established higher rates of heavy drinking and alcohol problems among Black and ..
  15. RACE AND ETHNIC DIFFERENCES IN U.S. BIRTH OUTCOMES
    Michael Grossman; Fiscal Year: 1990
    The specific aims of this project are to investigate the determinants of race and ethnic-specific birth outcomes in the U.S. and the source of differences in these outcomes...
  16. JACKSON HEART STUDY
    ASOKA S SRINIVASAN; Fiscal Year: 2011
    ..While biologic and genetic influences on disease risk may vary by race or ethnicity, they interact with and are modified by environmental variables such as cultural, psychosocial, and ..
  17. JACKSON HEART STUDY
    ASOKA S SRINIVASAN; Fiscal Year: 2013
    ..While biologic and genetic influences on disease risk may vary by race or ethnicity, they interact with and are modified by environmental variables such as cultural, psychosocial, and ..
  18. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
    ..While biologic and genetic influences on disease risk may vary by race or ethnicity, they interact with and are modified by environmental variables such as cultural, psychosocial, and ..
  19. JACKSON HEART STUDY
    HERMAN ALFRED TAYLOR; Fiscal Year: 2009
    ..While biologic and genetic influences on disease risk may vary by race or ethnicity, they interact with and are modified by environmental variables such as cultural, psychosocial, and ..
  20. JACKSON HEART STUDY
    Asoka Srinivasan; Fiscal Year: 2010
    ..While biologic and genetic influences on disease risk may vary by race or ethnicity, they interact with and are modified by environmental variables such as cultural, psychosocial, and ..
  21. JACKSON HEART STUDY
    Herman Taylor; Fiscal Year: 2010
    ..While biologic and genetic influences on disease risk may vary by race or ethnicity, they interact with and are modified by environmental variables such as cultural, psychosocial, and ..
  22. A dataset for the study of the social determinants of health.
    Peter A Muennig; Fiscal Year: 2010
    ..g., stress, pessimism) have been identified as contributors to health disparities by race, ethnicity, and SES...
  23. Nancy Berliner; Fiscal Year: 2015
    ..Furthermore, race appears to be an important variable affecting anemia prevalence, with African-Americans displaying significantly ..
  24. Epidemiologic Study of Sick Sinus Syndrome
    Alvaro Alonso; Fiscal Year: 2012
    ..aged 45 and older at baseline, to address the following aims: (1) To calculate the age, gender and race-specific incidence of SSS in ARIC and CHS, and estimate the total annual number of SSS events occurring in the US;(..
  25. Digna R Velez Edwards; Fiscal Year: 2016
    ..in 2,902 (1,451 fibroid cases and 1,451 controls) women from BioVU stratified by African American and Caucasian race. Secondary admixture mapping (AM) analyses will also be performed to identify chromosomal regions of interest to ..
  26. Race, Ethnicity, Nativity and Housing Outcomes in Los Angeles
    EILEEN DIAZ MCCONNELL; Fiscal Year: 2010
    ..situations such as cost burden, homeownership rates, and the value and equity of owned homes vary dramatically by race, ethnicity, and nativity in the United States...
  27. Understanding Race and Culture in Living Donor Kidney Transplantation
    Larissa Myaskovsky; Fiscal Year: 2013
    ..b>Race disparities exist in the (a) overall rate of transplantation;(b) type of transplant received [i.e...
  28. Sarah Miller; Fiscal Year: 2014
    ..by applicant): The National Research Council defines discrimination as "differential treatment on the basis of race that disadvantages a racial group...
  29. Training African American Peers as Patient Navigators for Colon Cancer Screening
    Lina Jandorf; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Cancer health disparities related to race and ethnicity are among the most serious problems facing the US health care system...
  30. Ann G Schwartz; Fiscal Year: 2016
    ..to the development of lung cancer and this association varies by the presence or absence of COPD, and by race. The goal is to develop a genetic profile based on SNPs and copy number variation in inflammation pathway genes ..
  31. Interpreting IV Estimates with Treatment Effect Heterogeneity: ACE/ARBs & Race
    John M Brooks; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Treatment rates vary dramatically across patients grouped by race, age, and gender...
  32. The Impact of Shared Decision-Making among African-Americans with Diabetes
    Monica E Peek; Fiscal Year: 2010
    ..I am an internist with an interest in exploring the impact of race/culture on the patient/provider relationship and reducing diabetic health disparities...
  33. Nicole L Nollen; Fiscal Year: 2016
    ..However, to-date, no adequately powered study, stratified on race, has been conducted to confirm this finding using a rigorous study design or to understand the mechanisms ..
  34. Modeling US Prostate Cancer Trends: PSA, Treatment & Ra*
    Ruth Etzioni; Fiscal Year: 2009
    ..experienced by whites and African Americans;and (4) Address whether disease natural history differs according to race, by estimating lead times associated with PSA screening that are consistent with incidence trends in whites and ..
  35. NAPS2-AS: Race Dependent Risk for Pancreatitis
    Dhiraj Yadav; Fiscal Year: 2013
    ....
  36. AMY DOGGETTE WATERMAN; Fiscal Year: 2015
    ..Louis, Missouri (465 African-Americans, 465 Whites) will be stratified by race and randomized to one of two education conditions (Explore Transplant Expert System vs. Standard Education Control)...
  37. Laura M Bogart; Fiscal Year: 2015
    ..engagement in care and treatment adherence than do Whites with HIV, and the predictors of these behaviors differ by race/ethnicity;however, few culturally relevant interventions have been tested...
  38. IGF::CT::IGF HANDLS HOME VISIT PROGRAM
    KATE TORRES; Fiscal Year: 2013
    ..is an interdisciplinary, community-based, prospective longitudinal epidemiologic study examining the influences of race and socioeconomic status (SES) on the development of age-related health disparities among socioeconomically diverse ..
  39. HANDLS Scan Substudy: Race, Socioeconomic status, and the Brain
    SHARI WALDSTEIN; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Pronounced health disparities associated with race and socioeconomic status (SES) are noted for brain health endpoints including stroke (particularly at younger ages), dementia, brain structure on ..
  40. Dawn O Kleindorfer; Fiscal Year: 2016
    ..and outcome of stroke within our biracial metropolitan population of 1,349,351, of whom 215,611 (15%) are of black race (US Census 2000)...
  41. Charmane I Eastman; Fiscal Year: 2016
    ..not only expand our knowledge of basic principles of the human circadian clock, but will also inform treatment of circadian-based sleep disorders, and highlight the need to consider race when determining the optimal treatment strategies.
  42. BIOMEDICAL (BASIC)
    Larry Moreland; Fiscal Year: 2009
    ..We will include a large sample of African Americans and Hispanics so that comparison across race and ethnic groups will be possible...
  43. Colorectal Cancer Screening in a Diverse Population
    NAVKIRAN SHOKAR; Fiscal Year: 2010
    ..data, especially in minority patients, and there remains a lack of understanding as to the mechanisms through which race/ethnicity affects screening behavior both for African Americans and Hispanics...
  44. SARAH P BLACKWELL; Fiscal Year: 2015
    ..conducts a survey of a random sample of mothers (stratified by non-Hispanic white, African American, and other race/ethnic groups) who have had a recent live birth...
  45. TAMELA EITLE; Fiscal Year: 2014
    ..S., there has been a relative paucity of research that has attempted to explain such behavior, including the "race gap"-why AIs are at an elevated risk for such behaviors (relative to whites)...
  46. Treatment Response in Ethnic Minority Individuals With Binge Eating Disorder
    Heather Thompson Brenner; Fiscal Year: 2010
    ..backgrounds to that of Caucasian participants in trials of BED and examine the interrelationships of race/ethnicity and other predictors such as pre-treatment severity, BMI, SES, and depression, and their relative impact ..
  47. Michael A Province; Fiscal Year: 2016
    ..pathways with high impact on adiposity traits, investigating whether the predominant pathways differ by sex and race. For these aims, we will work with studies from the GIANT (Genetic Investigation of ANthropometric Traits) ..
  48. Asim B Abdel-Mageed; Fiscal Year: 2015
    ..Our combined suppressive subtractive hybridization (SSH) analysis and race-based cDNA microarrays, showed a selective up-regulation of both the ERa co- repressor, SAFB2 and the ERf3 isoform, ..
  49. Binge Eating Disorder in an Ethnically Diverse Treatment-Seeking Population
    Lauren K Richards; Fiscal Year: 2013
    ..The second aim is to examine the relative influence of race/ethnicity, socioeconomic status, readiness for treatment, self-stigma, and stress on treatment retention and ..
  50. Barbara G Vickrey; Fiscal Year: 2016
    ..In this most diverse county in the US in race/ethnicity, we propose a multi-disciplinary, highly collaborative Program to create and test sustainable ..
  51. Stephen Sidney; Fiscal Year: 2016
    DESCRIPTION (provided by applicant): African Americans experience the highest rates of stroke of all race/ethnic groups In the US. Stroke in African American occurs at younger ages than Caucasians...
  52. Ralph L Sacco; Fiscal Year: 2014
    ..The reasons for these race-ethnic disparities are not entirely clear...
  53. Mary N Haan; Fiscal Year: 2015
    ..These processes differentially affect race/ethnic health disparities because, among disadvantaged populations, exposures to risk factors typically are higher, ..
  54. AMY LYNN BYERS; Fiscal Year: 2015
    ..Even more so, differences in suicidal behavior by race/ethnicity have hardly been investigated at all, as most studies are from non-diverse clinic samples...
  55. Amresh D Hanchate; Fiscal Year: 2016
    ..never been presented~ they will establish measurable target indicators, help set national priorities, and wil provide a mechanism with which to judge the relative impact of new policy initiatives for minorities by ethnicity and race.
  56. Racial & Ethnic Disparities in Incidence and Inpatient Outcomes of Acute Stroke
    Amresh D Hanchate; Fiscal Year: 2010
    ..A second concern is that these gains have been disproportionately distributed across race, ethnicity and socioeconomic status...
  57. KATHERINE MARGARET KEYES; Fiscal Year: 2016
    ..These projects are feasible only if I have protected time for new training and research, which K01 funding will provide. ..
  58. Determinants of Medication Adherence in HIV-Infected Adults with Hypertension
    Jeffrey J Weiss; Fiscal Year: 2011
    ..could be the target of future nurse-led interventions to improve adherence, with specific attention for the role of race and ethnicity...
  59. Ethnic Differences in Survival after Childhood ALL
    Smita Bhatia; Fiscal Year: 2009
    ..due primarily to non-adherence to 6MP, could explain the observed differences in outcome of childhood ALL by race/ethnicity...
  60. The Association Between Providers' Ethnic/Racial Biases and Hypertension Control
    Irene V Blair; Fiscal Year: 2010
    ..A random sample of the PCPs'hypertensive patients, stratified by ethnicity/race, will then be surveyed and using a retrospective cohort design, their electronic administrative records will be ..
  61. ICU Triage Decisions for Elders with End Stage Cancer: the Role of Patient Race
    Amber E Barnato; Fiscal Year: 2010
    ..there is some evidence that blacks may be more likely to prefer aggressive life-sustaining treatment than whites, race-based differences in communication around end-of-life ICU use likely also contribute to existing disparities...
  62. Etiology of breast development in the BCERC network: role of socioeconomic status
    DEJANA K BRAITHWAITE; Fiscal Year: 2010
    ..and BCERC Investigators Abstract This application is concerned with the role of socioeconomic status (SES) and race/ethnicity in the timing of breast development and menarche as an early life marker of breast cancer risk...
  63. Race and Health Outcomes Associated with Obesity
    Christina Wee; Fiscal Year: 2009
    ..Because obesity disproportionately affects African and Hispanic Americans, understanding the influence of race on obesity's impact on different health outcomes is especially vital to achieving these goals...
  64. Race & Breast Cancer Estrogen Receptor Status: Impact of Class and Missing Data
    Nancy Krieger; Fiscal Year: 2007
    ..Records include data on race/ethnicity, age at diagnosis, and tumor characteristics and are linked to 2000 census tract socioeconomic data...
  65. ALCOHOL & CRASH FATALITIES: ETHNIC GROUPS AT RISK
    Eduardo Romano; Fiscal Year: 2003
    ..available data set---the FARS, a large national fatal crash database with recently added information on the race/ethnicity of fatalities --- coupled with other data sources to examine the role of race/ethnicity in alcohol-, seat ..
  66. ALCOHOL CONSUMPTION & SPECIFIC CAUSES OF FATAL INJURIES
    Li Hui Chen; Fiscal Year: 2002
    ..usual drinking behavior and the incidence of various types of fatal injuries among different age, gender, and race/ethnic groups, and to use this to prevent further fatalities...
  67. Computational and Cell Culture Models for Mucus Clearance
    Richard Superfine; Fiscal Year: 2010
    ..When these assaults land at the mucus/air inter- face, the race between infection and clearance begins...
  68. Supplemental Vitamin D and Functional Outcomes in Early Adolescence
    Richard D Lewis; Fiscal Year: 2010
    ..Moreover, it is unknown if these requirements would differ by race. The specific aims of this project are to determine in early pubertal males (aged 10 to 13 years;n=160) and females ..
  69. HOST GENETIC DETERMINANTS OF HIV PATHOGENESIS
    Sunil Ahuja; Fiscal Year: 1999
    ..haplotypes that influence HIV transmission and disease progression; (2) determine whether CCR5 haplotypes produce race-specific effects on HIV susceptibility; (3) explore the impact of polymorphisms in CC chemokines and MHC genes on ..
  70. Tools for Measuring and Analyzing Cortisol Levels in Population Studies of Health
    Ana V Diez Roux; Fiscal Year: 2010
    Disparities in health by socioeconomic position and race/ethnicity have been documented for numerous health outcomes...
  71. Race Related Stressors and Preterm Birth in African American Women
    Carmen Giurgescu; Fiscal Year: 2009
    ..Attempts to explain the high rates of preterm birth in AA women have focused on race-related stressors of neighborhood environment and racial discrimination...
  72. RACIAL DISPARITIES IN MEDICATION USE IN US NURSING HOMES
    Kate Lapane; Fiscal Year: 2001
    ..Although we have considered race/ethnicity as an independent variable in analyses conducted for different purposes, we have yet to systematically ..
  73. Improving Data & Enhancing Access - (IDEA)
    VICTORIA ANN WARREN MEARS; Fiscal Year: 2010
    ..minority populations is complicated by the fact that public health data sources often fail to capture accurate race information...
  74. High Throughput Methods to Measure Disparities in Childhood Exposure to Tobacco
    Sharon E Murphy; Fiscal Year: 2010
    ..Notably, SHS exposure and the health effects of SHS vary by race, ethnicity and SES...
  75. Race and Long-Term Diabetes Self-Management in an HMO
    Dennis Ross Degnan; Fiscal Year: 2004
    This project will examine the complex relationships between race, diabetes self-management (including self-monitoring of blood glucose and diabetes drug therapy), glycemic control, and diabetes complications in a managed care setting ..
  76. Race in Physician Decision to Prescribe Opioid Analgesia
    JOSHUA SARVER; Fiscal Year: 2002
    ..to test this framework by conducting a series of mail surveys with case scenarios to determine: 1) the effect of race on physicians? use of analgesics for 3 acute, painful conditions (back pain with sciatica, ankle fracture, and ..
  77. Mapping "Race" and Inequality: Best Practices forTheorizing and Operationalizing
    NANCY contact LOPEZ; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Race continues to occupy a central role in policy discussions at all levels of government...
  78. Race and cardiac catheterization use in the setting of acute myocardial infarctio
    Saif Rathore; Fiscal Year: 2009
    ..In addition to determining overall agreement of self vs. documented-race, correlates of concordance in racial designation will be identified, and associations of race (administrative vs...
  79. DEATH RATES AND DEATH DATA FOR ASIAN AMERICAN ELDERLY
    Diane Lauderdale; Fiscal Year: 2003
    ..Death rates, routinely constructed by combining vital statistics and census data, are much lower for the race category "Asian or Pacific Islander (API)" than those for any other race category - less than two-thirds of white ..
  80. MORTALITY BY RACE AMONG LOW BIRTH WEIGHT INFANTS
    Robert Michielutte; Fiscal Year: 1990
    The primary goal of the proposed study is to examine the relationship between race and infant mortality in the context of a general model of risk factors for infant mortality...
  81. Exploring the Role of Race/Ethnicity & Family Influences to Reduce Youth Smoking
    E MELINDA MELINDA MAHABEE GITTENS; Fiscal Year: 2010
    ..Purpose. The aims of this application are to examine how race/ethnicity influences the family factors that are influential on adolescents'initial smoking initiation and ..
  82. Antioxidant Supplementation,Oxidative Stress & Enduranc*
    Maret Traber; Fiscal Year: 2002
    ..Subjects will consume a prescribed diet daily for 6 weeks prior to the race, race day and throughout the blood drawing schedule...