NimC2

Summary

Gene Symbol: NimC2
Description: Nimrod C2
Alias: BG:DS00180.14, CG18146, CG18146-PB, CT40902, DS00180.14, Dmel\CG18146, nimC2, CG18146 gene product from transcript CG18146-RC, CG18146-PA, CG18146-PB, CG18146-PC, NimC2-PA, NimC2-PB, NimC2-PC, nimrod C2
Species: fruit fly

Top Publications

  1. doi Evolution of genes and repeats in the Nimrod superfamily
    Kalman Somogyi
    Institute of Genetics, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary
    Mol Biol Evol 25:2337-47. 2008
  2. doi A conserved gene cluster as a putative functional unit in insect innate immunity
    Kalman Somogyi
    Institute of Genetics, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary
    FEBS Lett 584:4375-8. 2010
  3. pmc GeneID in Drosophila
    G Parra
    Grup de Recerca en Informàtica Mèdica, Institut Municipal d Investigacio Medica IMIM, Universitat Pompeu Fabra, E 08003 Barcelona, Spain
    Genome Res 10:511-5. 2000
  4. ncbi Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila
    Christine Kocks
    Laboratory of Developmental Immunology, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Cell 123:335-46. 2005
  5. ncbi Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells
    Johanna Ulvila
    Department of Pediatrics and Biocenter Oulu, University of Oulu, FIN 90014, Oulu, Finland
    J Biol Chem 281:14370-5. 2006
  6. ncbi Nimrod, a putative phagocytosis receptor with EGF repeats in Drosophila plasmatocytes
    Eva Kurucz
    Institute of Genetics, Biological Research Center of the Hungarian Academy of Sciences, H 6701 Szeged, Hungary
    Curr Biol 17:649-54. 2007

Scientific Experts

  • Kalman Somogyi
  • Johanna Ulvila
  • Christine Kocks
  • Eva Kurucz
  • Mika Ramet
  • G Parra
  • Elisabeth Gateff
  • Róbert Márkus
  • Peter Vilmos
  • Zsuzsanna Darula
  • Andor Udvardy
  • Tamas Lukacsovich
  • Dan Hultmark
  • János Zsámboki
  • Ildikó Krausz
  • Katalin Folkl-Medzihradszky
  • Istvan Ando
  • Carl Johan Zettervall
  • Mataleena Parikka
  • R Alan Ezekowitz
  • Raija Sormunen
  • Anni Kleino
  • Stephanie L Conto
  • Ju Hyun Cho
  • R Alan B Ezekowitz
  • Nadine Nehme
  • Lynda M Stuart
  • Thilo Stehle
  • Charles Strom
  • Alan M Pearson
  • Marie Meister
  • Charles Hetru
  • Jean Marc Reichhart
  • Jules A Hoffmann
  • Dominique Ferrandon
  • R Guigo
  • E Blanco

Detail Information

Publications6

  1. doi Evolution of genes and repeats in the Nimrod superfamily
    Kalman Somogyi
    Institute of Genetics, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary
    Mol Biol Evol 25:2337-47. 2008
    ..Our study presents an intriguing example how the evolution of multigene families may contribute to the complexity of the innate immune response...
  2. doi A conserved gene cluster as a putative functional unit in insect innate immunity
    Kalman Somogyi
    Institute of Genetics, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary
    FEBS Lett 584:4375-8. 2010
    ..This cluster has been a part of the Arthropod genomes for about 300-350 million years. The available data suggest that the Nimrod cluster is a functional module of the insect innate immune response...
  3. pmc GeneID in Drosophila
    G Parra
    Grup de Recerca en Informàtica Mèdica, Institut Municipal d Investigacio Medica IMIM, Universitat Pompeu Fabra, E 08003 Barcelona, Spain
    Genome Res 10:511-5. 2000
    ..These results show that the accuracy of GeneID predictions compares currently with that of other existing tools but that GeneID is likely to be more efficient in terms of speed and memory usage...
  4. ncbi Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila
    Christine Kocks
    Laboratory of Developmental Immunology, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Cell 123:335-46. 2005
    ..Our results suggest that Eater is a major phagocytic receptor for a broad range of bacterial pathogens in Drosophila and provide a powerful model to address the role of phagocytosis in vivo...
  5. ncbi Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells
    Johanna Ulvila
    Department of Pediatrics and Biocenter Oulu, University of Oulu, FIN 90014, Oulu, Finland
    J Biol Chem 281:14370-5. 2006
    ..Our data provide insight into the mechanism of dsRNA internalization by Drosophila cells. These results have implications for dsRNA delivery into mammalian cells...
  6. ncbi Nimrod, a putative phagocytosis receptor with EGF repeats in Drosophila plasmatocytes
    Eva Kurucz
    Institute of Genetics, Biological Research Center of the Hungarian Academy of Sciences, H 6701 Szeged, Hungary
    Curr Biol 17:649-54. 2007
    ..melanogaster and CED-1 from C. elegans. Together, they form a superfamily that also includes proteins that are encoded in the human genome...