Gr64b

Summary

Gene Symbol: Gr64b
Description: Gustatory receptor 64b
Alias: CG14986, CG32257, Dmel64b, Dmel\CG32257, GR64b, Gr64, anon-WO0118547.604, CG32257 gene product from transcript CG32257-RA, CG32257-PA, Gr64b-PA, gustatory receptor 64b
Species: fruit fly

Top Publications

  1. ncbi Trehalose sensitivity in Drosophila correlates with mutations in and expression of the gustatory receptor gene Gr5a
    K Ueno
    Graduate School of Information Sciences, Tohoku University, Sendai 980 8579, Japan
    Curr Biol 11:1451-5. 2001
  2. pmc A Drosophila gustatory receptor required for the responses to sucrose, glucose, and maltose identified by mRNA tagging
    Yuchen Jiao
    Department of Biological Chemistry, Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 104:14110-5. 2007
  3. pmc Two Gr genes underlie sugar reception in Drosophila
    Anupama Dahanukar
    Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520 8103, USA
    Neuron 56:503-16. 2007
  4. pmc Regulation of gustatory physiology and appetitive behavior by the Drosophila circadian clock
    Abhishek Chatterjee
    Department of Biology and Center for Biological Clocks Research, Texas A and M University, College Station, TX 77843 3258, USA
    Curr Biol 20:300-9. 2010
  5. pmc Sugar receptors in Drosophila
    Jesse Slone
    Duke University Medical Center, Department of Molecular Genetics and Microbiology, Durham, North Carolina 27710, USA
    Curr Biol 17:1809-16. 2007
  6. pmc Detection of sweet tastants by a conserved group of insect gustatory receptors
    Erica Gene Freeman
    Bioengineering Interdepartmental Graduate Program, Interdepartmental Neuroscience Program, and Department of Entomology, Institute of Integrative Genome Biology, University of California, Riverside, CA 92521
    Proc Natl Acad Sci U S A 111:1598-603. 2014
  7. pmc Gustatory and metabolic perception of nutrient stress in Drosophila
    Nancy J Linford
    Department of Molecular and Integrative Physiology
    Proc Natl Acad Sci U S A 112:2587-92. 2015
  8. pmc Drosophila sugar receptors in sweet taste perception, olfaction, and internal nutrient sensing
    Shinsuke Fujii
    Department of Cellular and Molecular Medicine, Texas A and M Health Science Center, College Station, TX 77845, USA
    Curr Biol 25:621-7. 2015
  9. pmc A genetic tool kit for cellular and behavioral analyses of insect sugar receptors
    Ahmet Yavuz
    a Department of Cellular and Molecular Medicine Texas A and M Health Science Center College Station, TX USA
    Fly (Austin) 8:189-96. 2014
  10. pmc Re-patterning sleep architecture in Drosophila through gustatory perception and nutritional quality
    Nancy J Linford
    Department of Molecular and Integrative Physiology, Geriatrics Center and Nathan Shock Center of Excellence in the Basic Biology of Aging, University of Michigan, Ann Arbor, Michigan, USA
    PLoS Genet 8:e1002668. 2012

Scientific Experts

  • Nancy J Linford
  • Lauren B Kent
  • Jesse Slone
  • Hubert Amrein
  • Ahmet Yavuz
  • Yuchen Jiao
  • Anupama Dahanukar
  • Shinsuke Fujii
  • Christopher Jagge
  • Erica Gene Freeman
  • Abhishek Chatterjee
  • Craig Montell
  • Seok Jun Moon
  • Hiroaki Matsunami
  • Xiangyu Song
  • Zev Wisotsky
  • K Ueno
  • Jerry H Houl
  • Shintaro Tanoue
  • Paul E Hardin
  • Xiaoyue Wang
  • Qiuting Ren
  • Joseph Daniels
  • John R Carlson
  • Jae Young Kwon
  • Ya Ting Lei
  • Y Mikuni
  • K Yamamoto
  • K Isono
  • M Ohta
  • H Morita
  • S Nakajima

Detail Information

Publications13

  1. ncbi Trehalose sensitivity in Drosophila correlates with mutations in and expression of the gustatory receptor gene Gr5a
    K Ueno
    Graduate School of Information Sciences, Tohoku University, Sendai 980 8579, Japan
    Curr Biol 11:1451-5. 2001
    ..Taken together, the mutation analyses support that Gr5a is allelic to Tre...
  2. pmc A Drosophila gustatory receptor required for the responses to sucrose, glucose, and maltose identified by mRNA tagging
    Yuchen Jiao
    Department of Biological Chemistry, Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 104:14110-5. 2007
    ..These data demonstrate that multiple Grs are coexpressed with Gr5a and that Drosophila Gr64a is required for the responses to multiple sugars...
  3. pmc Two Gr genes underlie sugar reception in Drosophila
    Anupama Dahanukar
    Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520 8103, USA
    Neuron 56:503-16. 2007
    ..The simplest interpretation of our results is that Gr5a and Gr64a are each capable of functioning independently of each other within individual sugar neurons and that they are the primary receptors used in the labellum to detect sugars...
  4. pmc Regulation of gustatory physiology and appetitive behavior by the Drosophila circadian clock
    Abhishek Chatterjee
    Department of Biology and Center for Biological Clocks Research, Texas A and M University, College Station, TX 77843 3258, USA
    Curr Biol 20:300-9. 2010
    ..Here we examine gustatory physiology, tastant-evoked appetitive behavior, and food ingestion to understand clock-dependent regulation of the Drosophila gustatory system...
  5. pmc Sugar receptors in Drosophila
    Jesse Slone
    Duke University Medical Center, Department of Molecular Genetics and Microbiology, Durham, North Carolina 27710, USA
    Curr Biol 17:1809-16. 2007
    ..Here, we show that the Gr64 genes encode receptors for numerous sugars...
  6. pmc Detection of sweet tastants by a conserved group of insect gustatory receptors
    Erica Gene Freeman
    Bioengineering Interdepartmental Graduate Program, Interdepartmental Neuroscience Program, and Department of Entomology, Institute of Integrative Genome Biology, University of California, Riverside, CA 92521
    Proc Natl Acad Sci U S A 111:1598-603. 2014
    ..Our results provide a molecular basis for tastant detection by the entire repertoire of sweet taste receptors in the fly and lay the foundation for studying Grs in mosquitoes and other insects that transmit deadly diseases. ..
  7. pmc Gustatory and metabolic perception of nutrient stress in Drosophila
    Nancy J Linford
    Department of Molecular and Integrative Physiology
    Proc Natl Acad Sci U S A 112:2587-92. 2015
    ....
  8. pmc Drosophila sugar receptors in sweet taste perception, olfaction, and internal nutrient sensing
    Shinsuke Fujii
    Department of Cellular and Molecular Medicine, Texas A and M Health Science Center, College Station, TX 77845, USA
    Curr Biol 25:621-7. 2015
    ..Thus, sugar receptors may contribute to feeding behavior via multiple sensory systems...
  9. pmc A genetic tool kit for cellular and behavioral analyses of insect sugar receptors
    Ahmet Yavuz
    a Department of Cellular and Molecular Medicine Texas A and M Health Science Center College Station, TX USA
    Fly (Austin) 8:189-96. 2014
    ..Thus, the precisely engineered genetic mutations of single Gr genes and construction of a sugar-blind strain provide powerful analytical tools for examining the roles of Drosophila and other insect sugar Gr genes in sweet taste. ..
  10. pmc Re-patterning sleep architecture in Drosophila through gustatory perception and nutritional quality
    Nancy J Linford
    Department of Molecular and Integrative Physiology, Geriatrics Center and Nathan Shock Center of Excellence in the Basic Biology of Aging, University of Michigan, Ann Arbor, Michigan, USA
    PLoS Genet 8:e1002668. 2012
    ..These results provide evidence that gustatory perception can alter arousal thresholds for sleep behavior in response to dietary cues and provide a mechanism by which organisms tune their behavior and physiology to environmental cues...
  11. pmc Taste and pheromone perception in mammals and flies
    Hiroaki Matsunami
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA
    Genome Biol 4:220. 2003
    ..Comparison of these systems in Drosophila and mouse uncovers clear differences and a few surprising similarities...
  12. pmc Gr64f is required in combination with other gustatory receptors for sugar detection in Drosophila
    Yuchen Jiao
    Department of Biological Chemistry, Department of Neuroscience, Center for Sensory Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Curr Biol 18:1797-801. 2008
    ..These seven transmembrane receptors include Gr5a and at least one member of the six genes in the Gr64 cluster (Gr64a), which are expressed in sugar-responsive neurons...
  13. pmc Evolution of the sugar receptors in insects
    Lauren B Kent
    Department of Entomology, University of Illinois at Urbana Champaign, 61801, USA
    BMC Evol Biol 9:41. 2009
    ..We examined the evolution of these SRs within the 12 available Drosophila genome sequences, as well as three mosquito, two moth, and beetle, bee, and wasp genome sequences...