pMUR050_005

Summary

Gene Symbol: pMUR050_005
Description: transposase
Species: Escherichia coli

Top Publications

  1. pmc Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum beta-lactamase encoded by an Escherichia coli integron gene
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Faculte de Medecine Paris Sud, France
    Antimicrob Agents Chemother 43:573-81. 1999
  2. pmc Characterization of In53, a class 1 plasmid- and composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    J Bacteriol 183:235-49. 2001
  3. pmc Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli
    Costas C Papagiannitsis
    Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas Sofias 127, Athens, Greece
    Antimicrob Agents Chemother 51:3763-7. 2007
  4. pmc New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate
    Kunikazu Yamane
    Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases, 4 7 1 Gakuen, Musashi Murayama, Tokyo 208 0011, Japan
    Antimicrob Agents Chemother 51:3354-60. 2007
  5. pmc SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli
    C C Papagiannitsis
    Laboratory of Bacteriology, Institut Pasteur Hellenique, Vas Sofias 127, Athens 11521, Greece
    Antimicrob Agents Chemother 51:2185-8. 2007
  6. pmc Emergence of CTX-M-15-producing enterobacteria in Cameroon and characterization of a blaCTX-M-15-carrying element
    J Gangoue-Pieboji
    Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas Sofias 127, Athens 11521, Greece
    Antimicrob Agents Chemother 49:441-3. 2005
  7. ncbi Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK
    N Woodford
    Antibiotic Resistance Monitoring and Reference Laboratory, Specialist and Reference Microbiology Division Colindale, Health Protection Agency, London
    J Antimicrob Chemother 54:735-43. 2004
  8. ncbi Structure and mode of transposition of Tn2555 carrying sucrose utilization genes
    Vera G Doroshenko
    Ajinomoto Genetika Research Institute, 1 st Dorozhnyi Proezd, B 1, Moscow 113545, Russian Federation
    FEMS Microbiol Lett 233:353-9. 2004
  9. pmc A new sulfonamide resistance gene (sul3) in Escherichia coli is widespread in the pig population of Switzerland
    Vincent Perreten
    Institute of Veterinary Bacteriology, University of Bern, Switzerland
    Antimicrob Agents Chemother 47:1169-72. 2003
  10. pmc Novel complex sul1-type integron in Escherichia coli carrying bla(CTX-M-9)
    Montserrat Sabaté
    Departament de Microbiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma, Av Sant Antoni M Claret 167, 08025 Barcelona, Spain
    Antimicrob Agents Chemother 46:2656-61. 2002

Scientific Experts

  • N Woodford
  • T Naas
  • Vera G Doroshenko
  • E Tzelepi
  • V Miriagou
  • L S Tzouvelekis
  • S Vourli
  • Costas C Papagiannitsis
  • Kunikazu Yamane
  • C C Papagiannitsis
  • J Gangoue-Pieboji
  • Vincent Perreten
  • Montserrat Sabaté
  • M Sabate
  • L Poirel
  • G Arlet
  • Kouji Kimura
  • Yoshichika Arakawa
  • Satowa Suzuki
  • Vivi Miriagou
  • Keigo Shibayama
  • Eva Tzelepi
  • A Loli
  • Haru Kato
  • Leonidas S Tzouvelekis
  • Toshifumi Konda
  • Naohiro Shibata
  • Jun ichi Wachino
  • P Ngassam
  • N J Legakis
  • Patrick Boerlin
  • E Lebessi
  • Susana Campoy
  • Jordi Barbe
  • Ferran Navarro
  • Beatriz Mirelis
  • Elisenda Miro
  • Guillem Prats
  • G Prats
  • R Tarrago
  • J Barbe
  • F Navarro
  • E Miro
  • C Verges
  • L Sundstrom
  • N Noguchi
  • P Nordmann
  • E B Chaibi
  • R Labia
  • M Guibert
  • E Heikkila
  • A Emura
  • H Matsuyama
  • O Skold
  • C Jansson
  • M Sasatsu
  • K Bremer
  • K O'Hara
  • M Kono
  • B Olsson-Liljequist
  • T Yamamoto
  • M Watanabe
  • T Sawai
  • K Matsumoto

Detail Information

Publications18

  1. pmc Molecular and biochemical characterization of VEB-1, a novel class A extended-spectrum beta-lactamase encoded by an Escherichia coli integron gene
    L Poirel
    Service de Bacteriologie Virologie, Hopital de Bicetre, Faculte de Medecine Paris Sud, France
    Antimicrob Agents Chemother 43:573-81. 1999
    ..Furthermore, blaVEB-1 is encoded on a large (> 100-kb) transferable plasmid found in a Klebsiella pneumoniae MG-2 isolated at the same time from the same patient, indicating a horizontal gene transfer...
  2. pmc Characterization of In53, a class 1 plasmid- and composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes
    T Naas
    Service de Bacteriologie Virologie, Hopital de Bicetre, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, 94275 Le Kremlin Bicetre, France
    J Bacteriol 183:235-49. 2001
    ..Target site duplication at both ends of the transposon indicated that the integron likely was inserted into the plasmid through a transpositional process. This is the first description of an integron located on a composite transposon...
  3. pmc Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli
    Costas C Papagiannitsis
    Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas Sofias 127, Athens, Greece
    Antimicrob Agents Chemother 51:3763-7. 2007
    ..Kinetics of beta-lactam hydrolysis and levels of resistance to beta-lactams showed that ACC-4 was more effective than ACC-1 against expanded-spectrum cephalosporins...
  4. pmc New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate
    Kunikazu Yamane
    Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases, 4 7 1 Gakuen, Musashi Murayama, Tokyo 208 0011, Japan
    Antimicrob Agents Chemother 51:3354-60. 2007
    ..coli was first identified. Surveillance of the qepA-harboring clinical isolates should be encouraged to minimize further dissemination of the kind of plasmid-dependent FQ resistance determinants among pathogenic microbes...
  5. pmc SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli
    C C Papagiannitsis
    Laboratory of Bacteriology, Institut Pasteur Hellenique, Vas Sofias 127, Athens 11521, Greece
    Antimicrob Agents Chemother 51:2185-8. 2007
    ..The interaction of SCO-1 with beta-lactams was similar to that of the CARB-type enzymes. Also, SCO-1 exhibited a 51% amino acid sequence identity with the RTG subgroup of chromosomal carbenicillinases (RTG-1, CARB-5, and CARB-8)...
  6. pmc Emergence of CTX-M-15-producing enterobacteria in Cameroon and characterization of a blaCTX-M-15-carrying element
    J Gangoue-Pieboji
    Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas Sofias 127, Athens 11521, Greece
    Antimicrob Agents Chemother 49:441-3. 2005
    ..A truncated form of this element in the second plasmid was identified...
  7. ncbi Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum beta-lactamases in the UK
    N Woodford
    Antibiotic Resistance Monitoring and Reference Laboratory, Specialist and Reference Microbiology Division Colindale, Health Protection Agency, London
    J Antimicrob Chemother 54:735-43. 2004
    ..e. MICs of cefotaxime > or = 8-fold higher than MICs of ceftazidime. Many were referred as being from community patients. We examined 291 CTX-M-producing isolates from the UK and investigated the genetic basis of their phenotype...
  8. ncbi Structure and mode of transposition of Tn2555 carrying sucrose utilization genes
    Vera G Doroshenko
    Ajinomoto Genetika Research Institute, 1 st Dorozhnyi Proezd, B 1, Moscow 113545, Russian Federation
    FEMS Microbiol Lett 233:353-9. 2004
    ..3 translocation from pBR325 to RP4 occurs via a cointegrate formation, mediated by one of the three IS26 copies, followed by its resolution due to RecA-dependent recombination between two direct IS26 copies flanking the donor replicon...
  9. pmc A new sulfonamide resistance gene (sul3) in Escherichia coli is widespread in the pig population of Switzerland
    Vincent Perreten
    Institute of Veterinary Bacteriology, University of Bern, Switzerland
    Antimicrob Agents Chemother 47:1169-72. 2003
    ..coli. Two copies of the insertion element IS15Delta/26 flanked the region containing sul3. The sul3 gene was detected in one-third of the sulfonamide-resistant pathogenic E. coli isolates from pigs in Switzerland...
  10. pmc Novel complex sul1-type integron in Escherichia coli carrying bla(CTX-M-9)
    Montserrat Sabaté
    Departament de Microbiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma, Av Sant Antoni M Claret 167, 08025 Barcelona, Spain
    Antimicrob Agents Chemother 46:2656-61. 2002
    ..Furthermore, a new insertion sequence, IS3000, has been found in In60. PCR analysis indicates that integron In60 is present in 33 of 34 nonclonal enterobacterial isolates carrying the putative beta-lactamase CTX-M-9...
  11. pmc Cloning and sequence of the gene encoding a novel cefotaxime-hydrolyzing beta-lactamase (CTX-M-9) from Escherichia coli in Spain
    M Sabate
    Departament de Microbiologia, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma 08025 Barcelona, Spain
    Antimicrob Agents Chemother 44:1970-3. 2000
    ..Outside of this region there are only six amino acids substitutions between both proteins...
  12. pmc Nucleotide sequence and characterization of erythromycin resistance determinant that encodes macrolide 2'-phosphotransferase I in Escherichia coli
    N Noguchi
    Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Japan
    Antimicrob Agents Chemother 39:2359-63. 1995
    ....
  13. ncbi A new dhfrVIII trimethoprim-resistance gene, flanked by IS26, whose product is remote from other dihydrofolate reductases in parsimony analysis
    L Sundstrom
    Department of Pharmaceutical Biosciences, Uppsala University, Sweden
    Gene 154:7-14. 1995
    ..Phylogeny parsimony analysis showed the dhfrVIII-encoded enzyme to be only remotely related to other known plasmid-mediated, drug-resistant DHFR. Only a few of the latter form well-supported monophyletic groups...
  14. ncbi Tn2610, a transposon involved in the spread of the carbenicillin-hydrolyzing beta-lactamase gene
    T Yamamoto
    Mol Gen Genet 189:282-8. 1983
    ..The characteristic DNA structure observed in various complex resistance transposons involved in the transposition of the carbenicillin-hydrolyzing beta-lactamase gene is discussed...
  15. pmc Organization of complex transposon Tn2610 carrying two copies of tnpA and tnpR
    T Yamamoto
    Department of Microbiology, School of Medicine, Chiba University, Japan
    Antimicrob Agents Chemother 33:746-50. 1989
    ..Possible evolutionary relationships among class II transposable elements are proposed on the basis of the genetic and structural organization of Tn2610...
  16. ncbi Characterization of In111, a class 1 integron that carries the extended-spectrum beta-lactamase gene blaIBC-1
    S Vourli
    Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas Sofias 127, Athens 11521, Greece
    FEMS Microbiol Lett 225:149-53. 2003
    ..The 3'CS included sulI, qacEDelta1, orf5 and orf6. In111 was bounded on the right by an inversely oriented IRt. The 5'CS was preceded by an intact IS26 element followed by an aphA1 gene...