lrhA

Summary

Gene Symbol: lrhA
Description: transcriptional repressor of flagellar, motility and chemotaxis genes
Alias: ECK2283, JW2284, genR, hexA
Species: Escherichia coli str. K-12 substr. MG1655

Top Publications

  1. ncbi Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli
    Caroline Blumer
    Institut für Mikrobiologie und Weinforschung, Johannes Gutenberg Universitat Mainz, Becherweg 15, 55099 Mainz, Germany
    Microbiology 151:3287-98. 2005
  2. ncbi Characteristics of the LrhA subfamily of transcriptional regulators from Sinorhizobium meliloti
    Mingsheng Qi
    Laboratory of Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China
    Acta Biochim Biophys Sin (Shanghai) 40:166-73. 2008
  3. doi Mutations upregulating the flhDC operon of Escherichia coli K-12
    Changhan Lee
    Department of Life Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305 701, Republic of Korea
    J Microbiol 51:140-4. 2013
  4. ncbi Transcriptional regulation of the proton translocating NADH dehydrogenase genes (nuoA-N) of Escherichia coli by electron acceptors, electron donors and gene regulators
    J Bongaerts
    Institut für Mikrobiologie und Weinforschung, Universitat Mainz, Germany
    Mol Microbiol 16:521-34. 1995
  5. pmc The LysR homolog LrhA promotes RpoS degradation by modulating activity of the response regulator sprE
    K E Gibson
    Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
    J Bacteriol 181:563-71. 1999
  6. pmc rpoS function is essential for bgl silencing caused by C-terminally truncated H-NS in Escherichia coli
    T Ohta
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa ku, Nagoya 464 8601, Japan
    J Bacteriol 181:6278-83. 1999
  7. ncbi LrhA as a new transcriptional key regulator of flagella, motility and chemotaxis genes in Escherichia coli
    D Lehnen
    Institut fur Mikrobiologie and Weinforschung, Johannes Gutenberg Universitat Mainz, Becherweg 15, 55099 Mainz, Germany
    Mol Microbiol 45:521-32. 2002
  8. pmc LrhA regulates rpoS translation in response to the Rcs phosphorelay system in Escherichia coli
    Celeste N Peterson
    Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
    J Bacteriol 188:3175-81. 2006
  9. pmc The Erwinia chrysanthemi pecT gene regulates pectinase gene expression
    N Surgey
    Laboratoire de Genetique Moleculaire des Microorganismes, Unité Recherche Associée, Villeurbanne, France
    J Bacteriol 178:1593-9. 1996
  10. ncbi The hexA gene of Erwinia carotovora encodes a LysR homologue and regulates motility and the expression of multiple virulence determinants
    S J Harris
    Department of Biochemistry, University of Cambridge, UK
    Mol Microbiol 28:705-17. 1998

Detail Information

Publications10

  1. ncbi Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli
    Caroline Blumer
    Institut für Mikrobiologie und Weinforschung, Johannes Gutenberg Universitat Mainz, Becherweg 15, 55099 Mainz, Germany
    Microbiology 151:3287-98. 2005
    ..The transcriptional regulator LrhA, which is known as a repressor of flagellar, motility and chemotaxis genes, regulates biofilm formation and ..
  2. ncbi Characteristics of the LrhA subfamily of transcriptional regulators from Sinorhizobium meliloti
    Mingsheng Qi
    Laboratory of Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China
    Acta Biochim Biophys Sin (Shanghai) 40:166-73. 2008
    ..and SMc04315, showed similar amino acid sequences (30%) and shared the conserved DNA-binding domain with LrhA, HexA, or DgdR...
  3. doi Mutations upregulating the flhDC operon of Escherichia coli K-12
    Changhan Lee
    Department of Life Sciences, Korea Advanced Institute of Science and Technology, Daejeon 305 701, Republic of Korea
    J Microbiol 51:140-4. 2013
    Bacterial motility is governed by the flhDC master operon that is under the control of factors like OmpR, LrhA, HdfR, and H-NS. Previously, derivatives of the wild-type MG1655 strain of E...
  4. ncbi Transcriptional regulation of the proton translocating NADH dehydrogenase genes (nuoA-N) of Escherichia coli by electron acceptors, electron donors and gene regulators
    J Bongaerts
    Institut für Mikrobiologie und Weinforschung, Universitat Mainz, Germany
    Mol Microbiol 16:521-34. 1995
    ..A 560 bp intergenic region upstream of the nuo locus was followed by a gene (designated lrhA for LysR homologue A) coding for a gene regulator similar to those of the LysR family...
  5. pmc The LysR homolog LrhA promotes RpoS degradation by modulating activity of the response regulator sprE
    K E Gibson
    Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
    J Bacteriol 181:563-71. 1999
    ..Mutations mapping to a previously identified gene of unknown function, lrhA, were obtained...
  6. pmc rpoS function is essential for bgl silencing caused by C-terminally truncated H-NS in Escherichia coli
    T Ohta
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa ku, Nagoya 464 8601, Japan
    J Bacteriol 181:6278-83. 1999
    ..Genetic analysis revealed that the two insertions are within the rpoS gene and in front of the lrhA gene, respectively...
  7. ncbi LrhA as a new transcriptional key regulator of flagella, motility and chemotaxis genes in Escherichia coli
    D Lehnen
    Institut fur Mikrobiologie and Weinforschung, Johannes Gutenberg Universitat Mainz, Becherweg 15, 55099 Mainz, Germany
    Mol Microbiol 45:521-32. 2002
    The function of the LysR-type regulator LrhA of Escherichia coli was defined by comparing whole-genome mRNA profiles from wild-type E. coli and an isogenic lrhA mutant on a DNA microarray...
  8. pmc LrhA regulates rpoS translation in response to the Rcs phosphorelay system in Escherichia coli
    Celeste N Peterson
    Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA
    J Bacteriol 188:3175-81. 2006
    ..One protein that reduces RpoS levels is the transcription factor LrhA, a global regulator of flagellar synthesis...
  9. pmc The Erwinia chrysanthemi pecT gene regulates pectinase gene expression
    N Surgey
    Laboratoire de Genetique Moleculaire des Microorganismes, Unité Recherche Associée, Villeurbanne, France
    J Bacteriol 178:1593-9. 1996
    ..coli protein LrhA. PecT represses the expression of pectate lyase genes pelC, pelD, pelE, pelL, and kdgC, activates pelB, and has no ..
  10. ncbi The hexA gene of Erwinia carotovora encodes a LysR homologue and regulates motility and the expression of multiple virulence determinants
    S J Harris
    Department of Biochemistry, University of Cambridge, UK
    Mol Microbiol 28:705-17. 1998
    ..carotovora (Ecc) and virulence and motility in Erwinia carotovora ssp. atroseptica (Eca). This gene, hexA (hyperproduction of exoenzymes), is a close relative of the Erwinia chrysanthemi (Echr) gene pecT and encodes a ..