ftsI

Summary

Gene Symbol: ftsI
Description: septum formation; penicillin-binding protein 3; peptidoglycan synthetase
Species: Escherichia coli O157:H7 EDL933

Top Publications

  1. pmc YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site
    Nienke Buddelmeijer
    Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:6316-21. 2002
  2. pmc Lrp, a major regulatory protein in Escherichia coli, bends DNA and can organize the assembly of a higher-order nucleoprotein structure
    Q Wang
    Section of Genetics and Development, Cornell University, Ithaca, NY 14853
    EMBO J 12:2495-501. 1993
  3. ncbi Lrp, a global regulatory protein of Escherichia coli, binds co-operatively to multiple sites and activates transcription of ilvIH
    Q Wang
    Section of Genetics and Development, Cornell University, Ithaca, NY 14853
    J Mol Biol 229:306-18. 1993
  4. ncbi Nucleotide sequence of the murE gene of Escherichia coli
    J S Tao
    Department of Biochemistry and Microbiology, University of Victoria, Canada
    Can J Microbiol 35:1051-4. 1989
  5. ncbi On the process of cellular division in Escherichia coli: nucleotide sequence of the gene for penicillin-binding protein 3
    M Nakamura
    Mol Gen Genet 191:1-9. 1983
  6. ncbi Binding of penicillin to thiol-penicillin-binding protein 3 of Escherichia coli: identification of its active site
    N Houba-Herin
    Mol Gen Genet 201:499-504. 1985
  7. pmc An amino acid substitution in penicillin-binding protein 3 creates pointed polar caps in Escherichia coli
    P E Taschner
    Department of Molecular Cell Biology, University of Amsterdam, The Netherlands
    J Bacteriol 170:4828-37. 1988
  8. pmc Determination of the cleavage site involved in C-terminal processing of penicillin-binding protein 3 of Escherichia coli
    H Nagasawa
    Department of Agricultural Chemistry, University of Tokyo, Japan
    J Bacteriol 171:5890-3. 1989
  9. ncbi Membrane topology of penicillin-binding protein 3 of Escherichia coli
    L D Bowler
    Microbial Genetics Group, School of Biological Sciences, University of Sussex, Falmer, Brighton, UK
    Mol Microbiol 3:1277-86. 1989
  10. pmc Escherichia coli mraR gene involved in cell growth and division
    M Ueki
    Institute of Applied Microbiology, University of Tokyo, Japan
    J Bacteriol 174:7841-3. 1992

Detail Information

Publications11

  1. pmc YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site
    Nienke Buddelmeijer
    Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:6316-21. 2002
    ..coli YgbQ to the constriction site depends on cell division proteins FtsQ and FtsL but not FtsW and FtsI, placing YgbQ in the sequential dependency order of proteins localizing to the division site...
  2. pmc Lrp, a major regulatory protein in Escherichia coli, bends DNA and can organize the assembly of a higher-order nucleoprotein structure
    Q Wang
    Section of Genetics and Development, Cornell University, Ithaca, NY 14853
    EMBO J 12:2495-501. 1993
    ..Lrp-induced DNA bending, and a natural sequence-directed bend that exists within ilvIH DNA, may be architectural elements that facilitate the assembly of a nucleoprotein complex...
  3. ncbi Lrp, a global regulatory protein of Escherichia coli, binds co-operatively to multiple sites and activates transcription of ilvIH
    Q Wang
    Section of Genetics and Development, Cornell University, Ithaca, NY 14853
    J Mol Biol 229:306-18. 1993
    ..We propose a model in which multiple binding sites contribute to the formation of a nucleoprotein complex, but only a particular proximal site positions Lrp properly so that it interacts with RNA polymerase...
  4. ncbi Nucleotide sequence of the murE gene of Escherichia coli
    J S Tao
    Department of Biochemistry and Microbiology, University of Victoria, Canada
    Can J Microbiol 35:1051-4. 1989
    ..The coding region consisted of 1413 base pairs and was separated from the ftsI (penicillin-binding protein 3) gene by 61 base pairs...
  5. ncbi On the process of cellular division in Escherichia coli: nucleotide sequence of the gene for penicillin-binding protein 3
    M Nakamura
    Mol Gen Genet 191:1-9. 1983
    We determined the nucleotide sequence of a DNA fragment containing the ftsI gene coding for the penicillin-binding protein 3 (PBP-3), an indispensable enzyme for cell division of Escherichia coli. The entire ftsI gene was within the 2...
  6. ncbi Binding of penicillin to thiol-penicillin-binding protein 3 of Escherichia coli: identification of its active site
    N Houba-Herin
    Mol Gen Genet 201:499-504. 1985
    ..For mutagenesis, the gene coding for PBP3 (ftsI) was inserted into the expression cloning vector pIN-IIB...
  7. pmc An amino acid substitution in penicillin-binding protein 3 creates pointed polar caps in Escherichia coli
    P E Taschner
    Department of Molecular Cell Biology, University of Amsterdam, The Netherlands
    J Bacteriol 170:4828-37. 1988
    ..The large change in the shape of the polar caps was accompanied by a small change in the kinetics of peptidoglycan synthesis and in the local rate of surface synthesis activity along the cell envelope...
  8. pmc Determination of the cleavage site involved in C-terminal processing of penicillin-binding protein 3 of Escherichia coli
    H Nagasawa
    Department of Agricultural Chemistry, University of Tokyo, Japan
    J Bacteriol 171:5890-3. 1989
    ..One lysyl peptide bond resisted both lysyl endopeptidase and trypsin and remained uncleaved in the peptide analyzed above...
  9. ncbi Membrane topology of penicillin-binding protein 3 of Escherichia coli
    L D Bowler
    Microbial Genetics Group, School of Biological Sciences, University of Sussex, Falmer, Brighton, UK
    Mol Microbiol 3:1277-86. 1989
    ....
  10. pmc Escherichia coli mraR gene involved in cell growth and division
    M Ueki
    Institute of Applied Microbiology, University of Tokyo, Japan
    J Bacteriol 174:7841-3. 1992
    The mraR gene, which has a coding frame of 363 bp and lies close to and upstream of the ftsI gene of Escherichia coli, is involved in both cell division and cell lysis...
  11. pmc FtsL, an essential cytoplasmic membrane protein involved in cell division in Escherichia coli
    L M Guzman
    Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts 02115
    J Bacteriol 174:7716-28. 1992
    We have identified a gene involved in bacterial cell division, located immediately upstream of the ftsI gene in the min 2 region of the Escherichia coli chromosome...