LYZ

Summary

Gene Symbol: LYZ
Description: lysozyme
Alias: LYZF1, lysozyme C, lysozyme (renal amyloidosis), lysozyme F1
Species: dog

Top Publications

  1. doi Lysozyme, a mediator of sepsis that deposits in the systemic vasculature and kidney as a possible mechanism of acute organ dysfunction
    Jose Gotes
    Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico and Departments of Pharmacology and Therapeutics, Medicine, and Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada
    Shock 41:256-65. 2014
  2. doi Spontaneous asparaginyl deamidation of canine milk lysozyme under mild conditions
    Yasuhiro Nonaka
    Graduate School of Science, Hokkaido University, Sapporo, Hokkaido, Japan
    Proteins 72:313-22. 2008
  3. doi Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation
    Steven N Mink
    Health Sciences Centre, Winnipeg, Manitoba, Canada R3A 1R9
    Am J Physiol Heart Circ Physiol 294:H1724-35. 2008
  4. doi Lysozyme, a mediator of sepsis that intrinsically generates hydrogen peroxide to cause cardiovascular dysfunction
    Steven N Mink
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Am J Physiol Heart Circ Physiol 297:H930-48. 2009

Scientific Experts

  • S Mink
  • Jose Gotes
  • Yasuhiro Nonaka
  • Hans Jacobs
  • Krika Kasian
  • Zhao Qin Cheng
  • Daisuke Akieda
  • Tomoyasu Aizawa
  • Makoto Demura
  • Masakatsu Kamiya
  • Nobuhisa Watanabe
  • Masahiro Watanabe
  • Masanori Yasui
  • Mineyuki Mizuguchi
  • Isao Tanaka
  • Keiichi Kawano

Detail Information

Publications4

  1. doi Lysozyme, a mediator of sepsis that deposits in the systemic vasculature and kidney as a possible mechanism of acute organ dysfunction
    Jose Gotes
    Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico and Departments of Pharmacology and Therapeutics, Medicine, and Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada
    Shock 41:256-65. 2014
    ..We conclude that Lzm-S can deposit in the systemic vasculature and kidneys in SS, where this deposition could lead to acute organ dysfunction. ..
  2. doi Spontaneous asparaginyl deamidation of canine milk lysozyme under mild conditions
    Yasuhiro Nonaka
    Graduate School of Science, Hokkaido University, Sapporo, Hokkaido, Japan
    Proteins 72:313-22. 2008
    ..Because the substitutions did not disrupt the structural formation of the native and molten globule states, they will enable more precise analyses for physical and structural studies...
  3. doi Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation
    Steven N Mink
    Health Sciences Centre, Winnipeg, Manitoba, Canada R3A 1R9
    Am J Physiol Heart Circ Physiol 294:H1724-35. 2008
    ..Lzm-S may contribute to the vasodilation that occurs in septic shock...
  4. doi Lysozyme, a mediator of sepsis that intrinsically generates hydrogen peroxide to cause cardiovascular dysfunction
    Steven N Mink
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Am J Physiol Heart Circ Physiol 297:H930-48. 2009
    ..This study shows that Lzm-S, a mediator of sepsis, is able to intrinsically generate H(2)O(2). Moreover, this generation may activate H(2)O(2)-dependent pathways leading to cardiovascular collapse in septic shock...