Gene Symbol: LYZ
Alias: LYZF1, lysozyme C, lysozyme (renal amyloidosis), lysozyme F1
- Lysozyme, a mediator of sepsis that deposits in the systemic vasculature and kidney as a possible mechanism of acute organ dysfunctionJose Gotes
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico and Departments of Pharmacology and Therapeutics, Medicine, and Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada
Shock 41:256-65. 2014..We conclude that Lzm-S can deposit in the systemic vasculature and kidneys in SS, where this deposition could lead to acute organ dysfunction. ..
- Spontaneous asparaginyl deamidation of canine milk lysozyme under mild conditionsYasuhiro Nonaka
Graduate School of Science, Hokkaido University, Sapporo, Hokkaido, Japan
Proteins 72:313-22. 2008..Because the substitutions did not disrupt the structural formation of the native and molten globule states, they will enable more precise analyses for physical and structural studies...
- Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparationSteven N Mink
Health Sciences Centre, Winnipeg, Manitoba, Canada R3A 1R9
Am J Physiol Heart Circ Physiol 294:H1724-35. 2008..Lzm-S may contribute to the vasodilation that occurs in septic shock...
- Lysozyme, a mediator of sepsis that intrinsically generates hydrogen peroxide to cause cardiovascular dysfunctionSteven N Mink
Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
Am J Physiol Heart Circ Physiol 297:H930-48. 2009..This study shows that Lzm-S, a mediator of sepsis, is able to intrinsically generate H(2)O(2). Moreover, this generation may activate H(2)O(2)-dependent pathways leading to cardiovascular collapse in septic shock...