Gene Symbol: CSK
Description: c-src tyrosine kinase
Alias: C-SRC kinase, tyrosine-protein kinase CSK
- Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cellsSeigo Itoh
Center for Cardiovascular Research, University of Rochester, Rochester, New York 14642, USA
J Biol Chem 280:26383-96. 2005..These data suggest a role for mitochondrial Dok-4 as an anchoring molecule for the tyrosine kinase c-Src, and in turn as a regulator of TNF-alpha-mediated ROS production and NF-kappaB activation...
- Cytokine-induced arginase activity in pulmonary endothelial cells is dependent on Src family tyrosine kinase activityRossana Chang
Center for Perinatal Research, Columbus, OH 43205, USA
Am J Physiol Lung Cell Mol Physiol 295:L688-97. 2008..These findings support our hypothesis that inflammatory stimuli lead to increased urea and NO production through a STK-mediated pathway. Furthermore, these results indicate that the STK Fyn plays a critical role in this process...
- Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cellsShi Pan
Aab Cardiovascular Research Institute, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Arterioscler Thromb Vasc Biol 29:895-901. 2009..Because tyrosine phosphorylation is a key regulatory pathway for VEGF-mediated endothelial cell (EC) responses, we investigated tyrosine phosphorylation of G6PD and the role of the nonreceptor tyrosine kinase Src...