gcy-35

Summary

Gene Symbol: gcy-35
Description: Guanylyl CYclase
Alias: Soluble guanylate cyclase gcy-35
Species: Caenorhabditis elegans

Top Publications

  1. pmc Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases
    Manuel Zimmer
    Howard Hughes Medical Institute, Laboratory of Neural Circuits and Behavior, The Rockefeller University, New York, NY 10065, USA
    Neuron 61:865-79. 2009
  2. ncbi Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue
    Jesse M Gray
    Howard Hughes Medical Institute and Department of Anatomy, The University of California, San Francisco, California 94143 0452, USA
    Nature 430:317-22. 2004
  3. pmc In vivo genetic dissection of O2-evoked cGMP dynamics in a Caenorhabditis elegans gas sensor
    Africa Couto
    Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
    Proc Natl Acad Sci U S A 110:E3301-10. 2013
  4. pmc Chemosensation of bacterial secondary metabolites modulates neuroendocrine signaling and behavior of C. elegans
    Joshua D Meisel
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Cell 159:267-80. 2014
  5. pmc Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans
    Calvin A Mok
    The Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada
    PLoS Genet 7:e1002335. 2011

Detail Information

Publications5

  1. pmc Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases
    Manuel Zimmer
    Howard Hughes Medical Institute, Laboratory of Neural Circuits and Behavior, The Rockefeller University, New York, NY 10065, USA
    Neuron 61:865-79. 2009
    ..Both sGC expression and cell-intrinsic dynamics contribute to the differential roles of URX and BAG in O2-dependent behaviors...
  2. ncbi Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue
    Jesse M Gray
    Howard Hughes Medical Institute and Department of Anatomy, The University of California, San Francisco, California 94143 0452, USA
    Nature 430:317-22. 2004
    ..elegans' preferred level, and require gcy-35 activity. Our results suggest that GCY-35 is regulated by molecular oxygen, and that social feeding can be a behavioural strategy for responding to hyperoxic environments...
  3. pmc In vivo genetic dissection of O2-evoked cGMP dynamics in a Caenorhabditis elegans gas sensor
    Africa Couto
    Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
    Proc Natl Acad Sci U S A 110:E3301-10. 2013
    ..This variability may reflect stochastic differences in expression of cGMP signaling components. Our work provides in vivo insights into the architecture of neuronal cGMP signaling. ..
  4. pmc Chemosensation of bacterial secondary metabolites modulates neuroendocrine signaling and behavior of C. elegans
    Joshua D Meisel
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Cell 159:267-80. 2014
    ....
  5. pmc Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans
    Calvin A Mok
    The Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada
    PLoS Genet 7:e1002335. 2011
    ..We propose that a misregulation of cGMP signalling, which underlies developmental and some behavioural defects of C. elegans bbs mutants, may also contribute to some BBS features in other organisms...