- Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclasesManuel Zimmer
Howard Hughes Medical Institute, Laboratory of Neural Circuits and Behavior, The Rockefeller University, New York, NY 10065, USA
Neuron 61:865-79. 2009..Both sGC expression and cell-intrinsic dynamics contribute to the differential roles of URX and BAG in O2-dependent behaviors...
- Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologueJesse M Gray
Howard Hughes Medical Institute and Department of Anatomy, The University of California, San Francisco, California 94143 0452, USA
Nature 430:317-22. 2004..elegans' preferred level, and require gcy-35 activity. Our results suggest that GCY-35 is regulated by molecular oxygen, and that social feeding can be a behavioural strategy for responding to hyperoxic environments...
- In vivo genetic dissection of O2-evoked cGMP dynamics in a Caenorhabditis elegans gas sensorAfrica Couto
Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom
Proc Natl Acad Sci U S A 110:E3301-10. 2013..This variability may reflect stochastic differences in expression of cGMP signaling components. Our work provides in vivo insights into the architecture of neuronal cGMP signaling. ..
- Chemosensation of bacterial secondary metabolites modulates neuroendocrine signaling and behavior of C. elegansJoshua D Meisel
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Cell 159:267-80. 2014....
- Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegansCalvin A Mok
The Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Canada
PLoS Genet 7:e1002335. 2011..We propose that a misregulation of cGMP signalling, which underlies developmental and some behavioural defects of C. elegans bbs mutants, may also contribute to some BBS features in other organisms...