gmhA

Summary

Gene Symbol: gmhA
Description: phosphoheptose isomerase
Species: Burkholderia pseudomallei K96243

Top Publications

  1. ncbi Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides
    Miguel A Valvano
    Department of Microbiology and Immunology and Medicine, University of Western Ontario, London, Ontario, N6A 5C1, Canada
    Microbiology 148:1979-89. 2002
  2. pmc Detection of bacterial virulence genes by subtractive hybridization: identification of capsular polysaccharide of Burkholderia pseudomallei as a major virulence determinant
    S L Reckseidler
    Department of Microbiology and Infectious Diseases, University of Calgary Health Sciences Center, Calgary, Alberta, Canada T2N 4N1
    Infect Immun 69:34-44. 2001
  3. pmc A preliminary X-ray study of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei
    Mi Sun Kim
    Ewha Womans University, Seoul, Republic of Korea
    Acta Crystallogr Sect F Struct Biol Cryst Commun 65:1110-2. 2009
  4. doi The structure of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei reveals a zinc binding site at the heart of the active site
    Nicholas J Harmer
    School of Biosciences, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UK
    J Mol Biol 400:379-92. 2010

Scientific Experts

Detail Information

Publications4

  1. ncbi Novel pathways for biosynthesis of nucleotide-activated glycero-manno-heptose precursors of bacterial glycoproteins and cell surface polysaccharides
    Miguel A Valvano
    Department of Microbiology and Immunology and Medicine, University of Western Ontario, London, Ontario, N6A 5C1, Canada
    Microbiology 148:1979-89. 2002
  2. pmc Detection of bacterial virulence genes by subtractive hybridization: identification of capsular polysaccharide of Burkholderia pseudomallei as a major virulence determinant
    S L Reckseidler
    Department of Microbiology and Infectious Diseases, University of Calgary Health Sciences Center, Calgary, Alberta, Canada T2N 4N1
    Infect Immun 69:34-44. 2001
    ..Thus, the combination of PCR-based subtractive hybridization, insertional inactivation, and animal virulence studies has facilitated the identification of an important virulence determinant in B. pseudomallei...
  3. pmc A preliminary X-ray study of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei
    Mi Sun Kim
    Ewha Womans University, Seoul, Republic of Korea
    Acta Crystallogr Sect F Struct Biol Cryst Commun 65:1110-2. 2009
    Sedoheptulose-7-phosphate isomerase (GmhA) converts d-sedoheptulose 7-phosphate to d,d-heptose 7-phosphate. This is the first step in the biosynthesis pathway of NDP-heptose, which is responsible for the pleiotropic phenotype...
  4. doi The structure of sedoheptulose-7-phosphate isomerase from Burkholderia pseudomallei reveals a zinc binding site at the heart of the active site
    Nicholas J Harmer
    School of Biosciences, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UK
    J Mol Biol 400:379-92. 2010
    ..The best characterized biosynthetic enzyme is GmhA, which catalyzes the conversion of sedoheptulose-7-phosphate into D-glycero-D-manno-heptopyranose-7-phosphate, the ..