Martin S Zinkernagel

Summary

Publications

  1. doi request reprint Acetazolamide influences ocular pulse amplitude
    Martin S Zinkernagel
    Department of Ophthalmology, Kantonsspital St Gallen, Switzerland
    J Ocul Pharmacol Ther 25:141-4. 2009
  2. doi request reprint Macular hole surgery in patients with end-stage choroideremia
    Martin S Zinkernagel
    Oxford Eye Hospital and Oxford University Hospitals, NHS Trust NIHR Biomedical Research Centre, John Radcliffe Hospital, Headley Way, Headington, UK
    Ophthalmology 120:1592-6. 2013
  3. doi request reprint Kinetics of ocular and systemic antigen-specific T-cell responses elicited during murine cytomegalovirus retinitis
    Martin S Zinkernagel
    Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia
    Immunol Cell Biol 90:330-6. 2012
  4. doi request reprint In vivo imaging of ocular MCMV infection
    Martin S Zinkernagel
    Department of Experimental Immunology, Centre for Ophthalmology and Visual Sciences, University of Western Australia, Perth, Australia
    Invest Ophthalmol Vis Sci 51:369-74. 2010
  5. doi request reprint T cell responses in experimental viral retinitis: mechanisms, peculiarities and implications for gene therapy with viral vectors
    Martin S Zinkernagel
    Ocular Immunology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia
    Prog Retin Eye Res 30:275-84. 2011
  6. doi request reprint Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection
    Martin S Zinkernagel
    Ocular Immunology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Australia
    Am J Pathol 182:875-85. 2013
  7. doi request reprint Retinal Ganglion Cell Layer Change in Patients Treated With Anti-Vascular Endothelial Growth Factor for Neovascular Age-related Macular Degeneration
    Marco Beck
    Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
    Am J Ophthalmol 167:10-7. 2016
  8. doi request reprint Macular atrophy in patients with long-term anti-VEGF treatment for neovascular age-related macular degeneration
    Marion R Munk
    Department of Ophthalmology, Department of Clinical Research, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
    Acta Ophthalmol 94:e757-e764. 2016
  9. ncbi request reprint Outcomes when Switching from a pro re nata Regimen to a Treat and Extend Regimen Using Aflibercept in Neovascular Age-Related Macular Degeneration
    Helena Giannakaki-Zimmermann
    Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
    Ophthalmologica . 2016
  10. pmc Differentiation between Good and Low-Responders to Intravitreal Ranibizumab for Macular Edema Secondary to Retinal Vein Occlusion
    Marcel N Menke
    Department of Ophthalmology, Cantonal Hospital Aarau, Aarau, Switzerland Department of Ophthalmology, Inselspital, University Hospital of Bern and University of Bern, Bern, Switzerland
    J Ophthalmol 2016:9875741. 2016

Collaborators

Detail Information

Publications24

  1. doi request reprint Acetazolamide influences ocular pulse amplitude
    Martin S Zinkernagel
    Department of Ophthalmology, Kantonsspital St Gallen, Switzerland
    J Ocul Pharmacol Ther 25:141-4. 2009
    ..To investigate the effect of systemic acetazolamide on ocular pulse amplitude (OPA) and on intraocular pressure (IOP)...
  2. doi request reprint Macular hole surgery in patients with end-stage choroideremia
    Martin S Zinkernagel
    Oxford Eye Hospital and Oxford University Hospitals, NHS Trust NIHR Biomedical Research Centre, John Radcliffe Hospital, Headley Way, Headington, UK
    Ophthalmology 120:1592-6. 2013
    ..To assess macular hole surgery in patients with end-stage choroideremia with regard to anatomic closure and visual outcome...
  3. doi request reprint Kinetics of ocular and systemic antigen-specific T-cell responses elicited during murine cytomegalovirus retinitis
    Martin S Zinkernagel
    Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Western Australia, Australia
    Immunol Cell Biol 90:330-6. 2012
    ..These data provide novel insights of how and where immune responses are initiated when viral antigen is present in the subretinal space...
  4. doi request reprint In vivo imaging of ocular MCMV infection
    Martin S Zinkernagel
    Department of Experimental Immunology, Centre for Ophthalmology and Visual Sciences, University of Western Australia, Perth, Australia
    Invest Ophthalmol Vis Sci 51:369-74. 2010
    ..To develop a technique by which murine cytomegalovirus (MCMV) infection can be confirmed and monitored in vivo in various ocular compartments and to investigate the dynamics and time course of primary ocular CMV infection...
  5. doi request reprint T cell responses in experimental viral retinitis: mechanisms, peculiarities and implications for gene therapy with viral vectors
    Martin S Zinkernagel
    Ocular Immunology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia
    Prog Retin Eye Res 30:275-84. 2011
    ..Furthermore, implications drawn from these models for gene therapy in retinal diseases are discussed...
  6. doi request reprint Interferon γ-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection
    Martin S Zinkernagel
    Ocular Immunology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Australia
    Am J Pathol 182:875-85. 2013
    ....
  7. doi request reprint Retinal Ganglion Cell Layer Change in Patients Treated With Anti-Vascular Endothelial Growth Factor for Neovascular Age-related Macular Degeneration
    Marco Beck
    Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
    Am J Ophthalmol 167:10-7. 2016
    ..To evaluate macular retinal ganglion cell thickness in patients with neovascular age-related macular degeneration (AMD) and intravitreal anti-vascular endothelial growth factor (VEGF) therapy...
  8. doi request reprint Macular atrophy in patients with long-term anti-VEGF treatment for neovascular age-related macular degeneration
    Marion R Munk
    Department of Ophthalmology, Department of Clinical Research, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
    Acta Ophthalmol 94:e757-e764. 2016
    ..To identify the prevalence and progression of macular atrophy (MA) in neovascular age-related macular degeneration (AMD) patients under long-term anti-vascular endothelial growth factor (VEGF) therapy and to determine risk factors...
  9. ncbi request reprint Outcomes when Switching from a pro re nata Regimen to a Treat and Extend Regimen Using Aflibercept in Neovascular Age-Related Macular Degeneration
    Helena Giannakaki-Zimmermann
    Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
    Ophthalmologica . 2016
    ..To investigate outcomes in patients with neovascular age-related macular degeneration (AMD) switched from a pro re nata regimen (PRN) to a treat and extend regimen (TER) under aflibercept...
  10. pmc Differentiation between Good and Low-Responders to Intravitreal Ranibizumab for Macular Edema Secondary to Retinal Vein Occlusion
    Marcel N Menke
    Department of Ophthalmology, Cantonal Hospital Aarau, Aarau, Switzerland Department of Ophthalmology, Inselspital, University Hospital of Bern and University of Bern, Bern, Switzerland
    J Ophthalmol 2016:9875741. 2016
    ..Approximately 30% of patients showed low response to ranibizumab after the loading phase and after 1 year of treatment. Two-thirds of patients that were low-responders after the loading phase remained low-responders after 1 year...
  11. pmc Functional and anatomical outcome of eyes with neovascular age-related macular degeneration treated with intravitreal ranibizumab following an exit strategy regimen
    Marcel N Menke
    Department of Ophthalmology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
    Br J Ophthalmol 98:1197-200. 2014
    ..To assess the functional and morphological outcome of eyes with neovascular AMD treated with intravitreal ranbizumab following an exit strategy treatment regime...
  12. doi request reprint Imaging of macrophage dynamics with optical coherence tomography in anterior ischemic optic neuropathy
    Despina Kokona
    Department of Ophthalmology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
    Exp Eye Res . 2016
    ..Our data suggests that activated macrophages can be identified as hyperreflective dots in OCT...
  13. doi request reprint RETINAL LAYER RESPONSE TO RANIBIZUMAB DURING TREATMENT OF DIABETIC MACULAR EDEMA: Thinner is Not Always Better
    Andreas Ebneter
    Department of Ophthalmology, Inselspital, Bern University Hospital and University of Bern, Switzerland and Department of Clinical Research, University Hospital Bern, Switzerland
    Retina 36:1314-23. 2016
    ..To identify individual retinal layer thickness changes associated with visual acuity gain in diabetic macular edema treated with ranibizumab using layer segmentation on high-resolution optical coherence tomography scans...
  14. pmc Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration
    Martin S Zinkernagel
    Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
    Sci Rep 7:40826. 2017
    ..These findings suggest that modifications in the intestinal microbiome are associated with AMD, inferring that this common sight threatening disease may be targeted by microbiome-altering interventions...
  15. doi request reprint Enhanced-depth optical coherence tomography for imaging horizontal rectus muscles in Graves' orbitopathy
    Nathanael U Häner
    Department of Ophthalmology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
    Graefes Arch Clin Exp Ophthalmol 253:1569-73. 2015
    ....
  16. doi request reprint The Presence of Intra- or Subretinal Fluid during the Loading Phase in the Treatment of Exudative Age-Related Macular Degeneration with Intravitreal Ranibizumab Assessed by Optical Coherence Tomography
    Andreas Ebneter
    Department of Ophthalmology, Inselspital, University of Bern, Bern, Switzerland
    Ophthalmologica 234:61-6. 2015
    ....
  17. pmc Prognostic significance of foveal capillary drop-out and previous panretinal photocoagulation for diabetic macular oedema treated with ranibizumab
    Andreas Ebneter
    Department of Ophthalmology, Bern University Hospital and University of Bern, Bern, Switzerland
    Br J Ophthalmol 100:365-70. 2016
    ..To investigate the prognostic significance of macular capillary drop-out and previous panretinal laser photocoagulation in diabetic macular oedema treated with intravitreal ranibizumab...
  18. pmc Metrics of the normal anterior sclera: imaging with optical coherence tomography
    Andreas Ebneter
    Department of Ophthalmology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
    Graefes Arch Clin Exp Ophthalmol 253:1575-80. 2015
    ..To investigate anterior scleral thickness in a cohort of healthy subjects using enhanced depth imaging anterior segment optical coherence tomography...
  19. pmc Investigation of retinal morphology alterations using spectral domain optical coherence tomography in a mouse model of retinal branch and central retinal vein occlusion
    Andreas Ebneter
    Department of Ophthalmology, Bern University Hospital, Inselspital, and University of Bern, Bern, Switzerland
    PLoS ONE 10:e0119046. 2015
    ..Retinal changes after experimental retinal vein occlusion in this mouse model can be non-invasively quantified by spectral domain optical coherence tomography, and may be used to monitor effects of potential therapeutic interventions. ..
  20. doi request reprint Scleral thinning after repeated intravitreal injections of antivascular endothelial growth factor agents in the same quadrant
    Martin S Zinkernagel
    Department of Ophthalmology, University Hospital Bern, Bern, Switzerland
    Invest Ophthalmol Vis Sci 56:1894-900. 2015
    ..We assessed the effects of intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy on scleral architecture using spectral domain anterior segment optical coherence tomography (OCT)...
  21. doi request reprint Fluorescence lifetime imaging of the ocular fundus in mice
    Chantal Dysli
    Department of Ophthalmology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    Invest Ophthalmol Vis Sci 55:7206-15. 2014
    ..We report quantitative and qualitative autofluorescence lifetime imaging of the ocular fundus in mice...
  22. doi request reprint Quantification of retinal layer thickness changes in acute macular neuroretinopathy
    Marion R Munk
    Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Switzerland Department of Ophthalmology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Switzerland
    Br J Ophthalmol . 2016
    ..To quantitatively evaluate retinal layer thickness changes in acute macular neuroretinopathy (AMN)...
  23. doi request reprint Senile scleral plaques imaged with enhanced depth optical coherence tomography
    Marco Beck
    Department of Ophthalmology, Inselspital, Bern University Hospital, Bern, Switzerland
    Acta Ophthalmol 93:e188-92. 2015
    ..The aim of this study was to characterize SSP using enhanced depth imaging spectral domain anterior segment optical coherence tomography (OCT) in a cohort of patients attending intravitreal injection clinics...
  24. doi request reprint Quantitative analysis of fluorescence lifetime measurements of the macula using the fluorescence lifetime imaging ophthalmoscope in healthy subjects
    Chantal Dysli
    Department of Ophthalmology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
    Invest Ophthalmol Vis Sci 55:2106-13. 2014
    ..We report here the characteristics and repeatability of FAF lifetime measurements of the human macula using a new fluorescence lifetime imaging ophthalmoscope (FLIO)...