Yi Zeng

Summary

Publications

  1. pmc Extended Fixed Attribute Dynamics Method and an Illustrative Application in Bio-demographic-genetic Analysis on Longevity
    Yi Zeng
    Center for Study of Aging and Human Development, Medical School of Duke University, Center for Healthy Aging and Development Studies, National School of Development, Peking University
    Annu Rev Gerontol Geriatr 33:217-232. 2013
  2. pmc Implications of changes in households and living arrangements for future home-based care needs and costs for disabled elders in China
    Yi Zeng
    Duke University, Durham, NC, USA Peking University, Beijing, China
    J Aging Health 27:519-50. 2015
  3. pmc Resilience significantly contributes to exceptional longevity
    Yi Zeng
    Center for the Study of Aging and Human Development and Geriatric Division of Medical School, Duke University, Box 3003, Room 1506, BUSSE Building, Durham, NC 27710, USA
    Curr Gerontol Geriatr Res 2010:525693. 2010
  4. pmc Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China
    Yi Zeng
    Center for the Study of Aging and Human Development, Geriatrics Division of School of Medicine, Duke University, Box 3003 Durham, NC 27710, USA
    BMC Geriatr 13:91. 2013
  5. pmc Household and living arrangement projections at the subnational level: an extended cohort-component approach
    Yi Zeng
    Center for the Study of Aging and Human Development and Geriatric Division of Medical School, Population Research Institute, Duke University, Box 3003, Durham, NC 27710, USA
    Demography 50:827-52. 2013
  6. pmc Health consequences of familial longevity influence among the Chinese elderly
    Yi Zeng
    Center for Study of Aging and Human Development, School of Medicine, Duke University, PO Box 3003, Durham, NC 27710, USA
    J Gerontol A Biol Sci Med Sci 68:473-82. 2013
  7. pmc Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults
    Yi Zeng
    Center for the Study of Aging and Human Development, School of Medicine, Duke University, Durham, NC 27710, USA
    J Gerontol A Biol Sci Med Sci 66:1054-61. 2011
  8. pmc Associations of environmental factors with elderly health and mortality in China
    Yi Zeng
    Correspondence can be sent to Prof Yi Zeng, Center for the Study of Aging and Human Development, Box 3003, Duke University, Durham, NC 27710 Reprints can be ordered at http www ajph org by clicking the Reprints Eprints link
    Am J Public Health 100:298-305. 2010
  9. ncbi request reprint [Main dimensions of health status among the Chinese elderly]
    Yi Zeng
    China Center for Economic Research, National School of Development, Peking University, Beijing 100871, China
    Zhonghua Yu Fang Yi Xue Za Zhi 44:108-14. 2010
  10. pmc Effects of FOXO genotypes on longevity: a biodemographic analysis
    Yi Zeng
    Center for the Study of Aging and Human Development, Medical School of Duke University, Durham, NC 27710, USA
    J Gerontol A Biol Sci Med Sci 65:1285-99. 2010

Collaborators

Detail Information

Publications49

  1. pmc Extended Fixed Attribute Dynamics Method and an Illustrative Application in Bio-demographic-genetic Analysis on Longevity
    Yi Zeng
    Center for Study of Aging and Human Development, Medical School of Duke University, Center for Healthy Aging and Development Studies, National School of Development, Peking University
    Annu Rev Gerontol Geriatr 33:217-232. 2013
    ..We also discuss the strengths and limitations of the FAD method...
  2. pmc Implications of changes in households and living arrangements for future home-based care needs and costs for disabled elders in China
    Yi Zeng
    Duke University, Durham, NC, USA Peking University, Beijing, China
    J Aging Health 27:519-50. 2015
    ..To better understand future home-based care needs and costs for disabled elders in China...
  3. pmc Resilience significantly contributes to exceptional longevity
    Yi Zeng
    Center for the Study of Aging and Human Development and Geriatric Division of Medical School, Duke University, Box 3003, Room 1506, BUSSE Building, Durham, NC 27710, USA
    Curr Gerontol Geriatr Res 2010:525693. 2010
    ..These findings indicate that policies and programs to promote resilience would have long-term and positive effects on the well-being and longevity for senior citizens and their families...
  4. pmc Interactions between social/ behavioral factors and ADRB2 genotypes may be associated with health at advanced ages in China
    Yi Zeng
    Center for the Study of Aging and Human Development, Geriatrics Division of School of Medicine, Duke University, Box 3003 Durham, NC 27710, USA
    BMC Geriatr 13:91. 2013
    ..This study intends to fill in this research gap...
  5. pmc Household and living arrangement projections at the subnational level: an extended cohort-component approach
    Yi Zeng
    Center for the Study of Aging and Human Development and Geriatric Division of Medical School, Population Research Institute, Duke University, Box 3003, Durham, NC 27710, USA
    Demography 50:827-52. 2013
    ..Finally, the limitations of the present study and potential future lines of research are discussed...
  6. pmc Health consequences of familial longevity influence among the Chinese elderly
    Yi Zeng
    Center for Study of Aging and Human Development, School of Medicine, Duke University, PO Box 3003, Durham, NC 27710, USA
    J Gerontol A Biol Sci Med Sci 68:473-82. 2013
    ..Yet, there are few extant studies that inform this topic; this study expands this literature...
  7. pmc Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults
    Yi Zeng
    Center for the Study of Aging and Human Development, School of Medicine, Duke University, Durham, NC 27710, USA
    J Gerontol A Biol Sci Med Sci 66:1054-61. 2011
    ..Further studies with richer biomarkers are warranted for deeper understanding of the biological mechanisms...
  8. pmc Associations of environmental factors with elderly health and mortality in China
    Yi Zeng
    Correspondence can be sent to Prof Yi Zeng, Center for the Study of Aging and Human Development, Box 3003, Duke University, Durham, NC 27710 Reprints can be ordered at http www ajph org by clicking the Reprints Eprints link
    Am J Public Health 100:298-305. 2010
    ..We examined the effects of community socioeconomic conditions, air pollution, and the physical environment on elderly health and survival in China...
  9. ncbi request reprint [Main dimensions of health status among the Chinese elderly]
    Yi Zeng
    China Center for Economic Research, National School of Development, Peking University, Beijing 100871, China
    Zhonghua Yu Fang Yi Xue Za Zhi 44:108-14. 2010
    ..To analyze the dimensions of health status among the Chinese elderly...
  10. pmc Effects of FOXO genotypes on longevity: a biodemographic analysis
    Yi Zeng
    Center for the Study of Aging and Human Development, Medical School of Duke University, Durham, NC 27710, USA
    J Gerontol A Biol Sci Med Sci 65:1285-99. 2010
    ..05); G × E interactions between FOXO1A-209 and regular exercise increase survival likelihood by 31%-32% (p < .05)...
  11. pmc Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages
    Yi Zeng
    1 Center for the Study of Aging and Human Development and Geriatrics Division, Medical School of Duke University, Durham, North Carolina
    Rejuvenation Res 19:195-203. 2016
    ....
  12. doi request reprint The prevalence of drug resistance mutations among treatment-naive HIV-infected individuals in Beijing, China
    Jing Rong Ye
    National Institute for Viral Disease Control and Prevention, China Center for Disease Prevention and Control, Beijing, China
    AIDS Res Hum Retroviruses 28:418-23. 2012
    ....
  13. ncbi request reprint [Molecular-epidemiological characteristics of HIV-1 isolated from newly diagnosed female subjects in Beijing, 2006 - 2010]
    Jing Rong Ye
    National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Zhonghua Liu Xing Bing Xue Za Zhi 34:49-52. 2013
    ..To analyze the molecular-epidemiological characteristics of HIV-1 strains prevailing among female people living with HIV in Beijing...
  14. pmc Phylogenetic and temporal dynamics of human immunodeficiency virus type 1B in China: four types of B strains circulate in China
    Jingrong Ye
    1 Beijing Center for Disease Prevention and Control, Beijing, China
    AIDS Res Hum Retroviruses 30:920-6. 2014
    ..The data presented here offer a new perspective on the epidemic of HIV-1 subtype B in China...
  15. pmc Novel loci and pathways significantly associated with longevity
    Yi Zeng
    Center for the Study of Aging and Human Development and Geriatrics Division, Medical School of Duke University, Durham, North Carolina, USA
    Sci Rep 6:21243. 2016
    ..This study suggests protective mechanisms including immunity and nutrient metabolism and their interactions with environmental stress play key roles in human longevity...
  16. pmc GxE interactions between FOXO genotypes and drinking tea are significantly associated with prevention of cognitive decline in advanced age in China
    Yi Zeng
    Center for the Study of Aging and Human Development and Geriatrics Division, Medical School of Duke University, Durham, North Carolina Center for Healthy Aging and Development Studies, National School of Development, Peking University, Beijing, China
    J Gerontol A Biol Sci Med Sci 70:426-33. 2015
    ..Our empirical findings imply that the health benefits of particular nutritional interventions, including tea drinking, may, in part, depend upon individual genetic profiles. ..
  17. pmc Common genetic variants of the β2-adrenergic receptor affect its translational efficiency and are associated with human longevity
    Ling Zhao
    Department of Human Population Genetics, Institute of Molecular Medicine, Peking University, 5 Yiheyuan Road, Beijing, 100871, China
    Aging Cell 11:1094-101. 2012
    ..002) in transfected HEK293 cells. Thus, our data indicate that enhanced production of β2-adrenergic receptors caused by genetic variants is inversely associated with human lifespan...
  18. doi request reprint Genetic diversity of HIV type 1 isolated from newly diagnosed subjects (2006-2007) in Beijing, China
    Jing Rong Ye
    National Institute for Viral Disease Control and Prevention, China Center for Disease Prevention and Control, Beijing, China
    AIDS Res Hum Retroviruses 28:119-23. 2012
    ..5%) followed by CRF01_AE (25.0%), B (20.0%), and B' (15.7%). The data from this study indicate the existence of multiple HIV-1 subtypes or CRFs in Beijing and may be proven useful in the development of vaccine candidates in the future...
  19. pmc Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations
    Yang Li
    Department of Human Population Genetics, Institute of Molecular Medicine, Peking University, Beijing, China
    Hum Mol Genet 18:4897-904. 2009
    ..Thus, we demonstrate that, unlike FOXO3A, FOXO1A is more closely associated with human female longevity, suggesting that the genetic contribution to longevity trait may be affected by genders...
  20. pmc A U-shaped Association Between Blood Pressure and Cognitive Impairment in Chinese Elderly
    Yue Bin Lv
    Institute of Environmental Health and Related Products Safety, Chinese Center for Disease Control and Prevention, Beijing, China
    J Am Med Dir Assoc 18:193.e7-193.e13. 2017
    ..The study objective was to determine whether blood pressure is associated with cognitive impairment in the elderly, and, if so, to accurately describe the association...
  21. pmc Birth measurements, family history, and environmental factors associated with later-life hypertensive status
    Xia Chen
    Clinical Pharmacological Research Center, Peking Union Medical College Hospital, Academy of Chinese Medical Sciences, Beijing, China
    Am J Hypertens 25:464-71. 2012
    ..This birth cohort study was conducted to investigate the contribution of prenatal and antenatal environmental exposures to later-life hypertensive status...
  22. doi request reprint The effects of China's universal two-child policy
    Yi Zeng
    National School of Development and Raissun Institute for Advanced Studies, Peking University, Beijing, China Center for Study of Aging and Human Development and Geriatrics Division, Duke University, Durham, NC, USA
    Lancet 388:1930-1938. 2016
    ..In the meantime, more sound policy actions are needed to meet the social, health, and care needs of the elderly population...
  23. doi request reprint GSTM1 and GSTT1 gene deletions and the risk for nasopharyngeal carcinoma in Han Chinese
    Xiuchan Guo
    State Key Laboratory for Infectious Diseases Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese CDC, Beijing, China
    Cancer Epidemiol Biomarkers Prev 17:1760-3. 2008
    ..Our results suggest that the GSTM1/GSTT1-double null genotype may be a risk factor for nasopharyngeal carcinoma among males in southern China, but this result warrants confirmation in other studies...
  24. pmc The principal genetic determinants for nasopharyngeal carcinoma in China involve the HLA class I antigen recognition groove
    Minzhong Tang
    College of Life Science and Bio engineering, Beijing University of Technology, Beijing, China
    PLoS Genet 8:e1003103. 2012
    ....
  25. ncbi request reprint A new method for correcting under-estimation of disabled life expectancy and an application to the Chinese oldest-old
    Yi Zeng
    Center for Demographic Studies, Department of Sociology, Duke University, Campus Drive, Box 90408, Durham, NC 27708, USA
    Demography 41:335-61. 2004
    ....
  26. doi request reprint The hemodynamic effect of the support mode for the intra-aorta pump on the cardiovascular system
    Bin Gao
    School of Life Science and BioEngineering, Beijing University of Technology, Beijing, China
    Artif Organs 37:157-65. 2013
    ..55 mm Hg.s/mL). In brief, the intra-aorta pump under "co-pulse" mode support is beneficial for improving myocardial perfusion and restoring pulsatility of AP, while "counter-pulse" mode is beneficial to the perfusion of vital organs...
  27. pmc Gender-dependent association of body mass index and waist circumference with disability in the Chinese oldest old
    Zhaoxue Yin
    Division of Non communicable Diseases Control and Community Health, Chinese Center for Disease Control and Prevention, Beijing, China
    Obesity (Silver Spring) 22:1918-25. 2014
    ..To explore associations of BMI and waist circumference (WC) with disability among the Chinese oldest old...
  28. ncbi request reprint Older Parents Benefit More in Health Outcome From Daughters' Than Sons' Emotional Care in China
    Yi Zeng
    Duke University, Durham, NC, USA Peking University, Beijing, China
    J Aging Health . 2016
    ..To examine whether older parents in China would benefit more from daughters' care than from sons' emotional care...
  29. pmc Prevalence and Risk Factors of Atrial Fibrillation in Chinese Elderly: Results from the Chinese Longitudinal Healthy Longevity Survey
    Choy Lye Chei
    Center for the Study of Aging and Human Development and the Geriatric Division of School of Medicine, Duke University, Durham, NC, USA Center for Study of Healthy Aging and Development Studies, National School of Development, Peking University, Beijing 100871, China
    Chin Med J (Engl) 128:2426-32. 2015
    ..Prevalence of AF differs with each population studied, and research on non-Western populations and the oldest old is scarce...
  30. pmc Phylogenetic and temporal dynamics of human immunodeficiency virus type 1 CRF01_AE in China
    Jingrong Ye
    Beijing Center for Disease Prevention and Control, Beijing, China
    PLoS ONE 8:e54238. 2013
    ..The time of the most recent common ancestor (tMRCA) of four CRF01_AE clusters ranged from the years 1990.9 to 2003.8 in different regions of China. This is the first phylogenetic and temporal dynamics study of HIV-1 CRF01_AE in China...
  31. pmc Tea consumption and mortality in the oldest-old Chinese
    Rongping Ruan
    School of Agricultural Economics and Rural Development, Renmin University of China, Beijing, China
    J Am Geriatr Soc 61:1937-42. 2013
    ..To investigate the association between tea consumption and mortality in the oldest-old Chinese...
  32. doi request reprint Development of ventricular assist devices in China: present status, opportunities and challenges
    Kaiyun Gu
    School of Life Science and BioEngineering, Beijing University of Technology, Beijing, China
    Eur J Cardiothorac Surg 46:179-85. 2014
    ..This article provides an overview of the present development of experimental and clinical research on VADs in China. In addition, the challenges for the clinical development of mechanical circulatory support in China are discussed. ..
  33. doi request reprint The hemodynamic effect of phase differences between the BJUT-II ventricular assist device and native heart on the cardiovascular system
    Kaiyun Gu
    College of Life Science and Bioengineering, Beijing University of Technology, Beijing, China
    Artif Organs 38:914-23. 2014
    ..According to the output of the WDA, 30° is considered to be the optimal phase difference for the BJUT-II VAD...
  34. doi request reprint Demographics, Phenotypic Health Characteristics and Genetic Analysis of Centenarians in China
    Yi Zeng
    Center for Healthy Aging and Development Studies, National School of Development, Raissun Institute for Advanced Studies, Peking University, China Center for the Study of Aging and Human Development, Medical School of Duke University, United States Electronic address
    Mech Ageing Dev . 2016
    ..We also highlight colleagues' and our own studies on longevity candidate genes and gene-environment interaction analyses. Finally, we discuss limitations inherent in our studies of centenarians in China and further research perspectives...
  35. ncbi request reprint Genetic and Phenotypic Analysis of CRF01_AE HIV-1 env Clones from Patients Residing in Beijing, China
    Danying Chen
    1 College of Life Science and Bioengineering, Beijing University of Technology, Beijing, China
    AIDS Res Hum Retroviruses 32:1113-1124. 2016
    ..These findings are likely to have important implications for the design of an effective HIV vaccine and relevant therapeutic drugs...
  36. pmc Sequence analysis of the gag-pol gene of human immunodeficiency virus type 1 of intersubtype (B'/C) recombinant strain in Beijing, China
    Jing Rong Ye
    National Institute for Viral Disease Control and Prevention, China Center for Disease Prevention and Control, Beijing, China
    AIDS Res Hum Retroviruses 27:331-7. 2011
    ..In addition, one new B'/C recombinant was detected. These results may contribute to an understanding of HIV-1 in Beijing...
  37. pmc TALEN-mediated Nanog disruption results in less invasiveness, more chemosensitivity and reversal of EMT in Hela cells
    Yan Ding
    Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, China College of Life Science and Bioengineering, Beijing University of Industry, Beijing, China
    Oncotarget 5:8393-401. 2014
    ....
  38. pmc Relationship between birth size and coronary heart disease in China
    Zhongjie Fan
    Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
    Ann Med 42:596-602. 2010
    ..Clinical epidemiological studies suggested a link between fetal growth conditions and later coronary heart disease (CHD) in adult life. However, no such studies have been conducted in a Chinese population...
  39. pmc Estimating the number of people living with HIV/AIDS in China: 2003-09
    Ning Wang
    Chinese Center for Disease Control and Prevention, Beijing, China
    Int J Epidemiol 39:ii21-8. 2010
    ..Subsequent national estimation exercises were carried out in 2005, 2007 and 2009. We describe these estimation processes and present the results of China's HIV/AIDS estimation exercises from 2003 to 2009...
  40. doi request reprint Potent specific immune responses induced by prime-boost-boost strategies based on DNA, adenovirus, and Sendai virus vectors expressing gag gene of Chinese HIV-1 subtype B
    Shuangqing Yu
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China
    Vaccine 26:6124-31. 2008
    ..Its further studies as a promising scheme for therapeutic and/or prophylactic HIV-1 vaccines should be grounded...
  41. pmc Genetic Polymorphisms of CYP2E1, GSTP1, NQO1 and MPO and the Risk of Nasopharyngeal Carcinoma in a Han Chinese Population of Southern China
    Xiuchan Guo
    State Key Laboratory for Infectious Diseases Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese Centers for Disease Control and Prevention, Beijing, China
    BMC Res Notes 3:212. 2010
    ....
  42. pmc Low-density lipoprotein cholesterol was inversely associated with 3-year all-cause mortality among Chinese oldest old: data from the Chinese Longitudinal Healthy Longevity Survey
    Yue Bin Lv
    Division of Non Communicable Disease Control and Community Health, Chinese Center for Disease Control and Prevention, Beijing, China
    Atherosclerosis 239:137-42. 2015
    ..The goal of this study was to assess the relationship between LDL-C and all-cause mortality among Chinese oldest old (aged 80 and older) in a prospective cohort study...
  43. ncbi request reprint [Genetic analysis of the complete env genes of HIV-1 from paid blood donors in Henan province]
    Xia Feng
    State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, China CDC, Beijing, China
    Bing Du Xue Bao 25:88-94. 2009
    ..Further study to elucidate the correlation of the env genotype to functionally relevant motifs is necessary and that will aid vaccine and novel drug design...
  44. ncbi request reprint [Association between sequence variation of Env, Gag genes from the same source and HIV-1 disease progression and host genetic polymorphism]
    Li shi Bai
    National Institute for Viral Disease Control and Prevention, China CDC, Beijing, 100052, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 21:153-5. 2007
    ..To understand the relationship between the HIV-1 viral sequence variation and host factors associated with HIV-1 disease progression...
  45. doi request reprint Human umbilical cord-derived MSC culture: the replacement of animal sera with human cord blood plasma
    Yan Ding
    College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100124, China
    In Vitro Cell Dev Biol Anim 49:771-7. 2013
    ..Such dialyzed human UCBP is fully comparable with, if not superior to, FBS in deriving and culturing hUC-MSCs. ..
  46. ncbi request reprint [Expression of peroxiredoxin III in cervical lesions]
    Lian qin Li
    Obstetrics and Gynecology Center, Tsinghua University Second Hospital, Beijing, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 23:443-5. 2009
    ..To investigate the expression feature of peroxiredoxin III in cervical lesions and to further understand the mechanism for cervical cancer development/progression...
  47. doi request reprint Physiological controller of an intra-aorta pump based on baroreflex sensitivity
    Bin Gao
    School of Life Science and BioEngineering, Beijing University of Technology, Beijing, China
    Artif Organs 36:1015-25. 2012
    ..The optimum operating point for the pump can be detected by the proposed control strategy without the need to set a reference value for the control variable by operators...
  48. ncbi request reprint [Correlation between load of polyomavirus and hemorrhagic cystitis]
    Chun Rong Tong
    Beijing Dao pei Hospital, Beijing, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 21:244-6. 2007
    ..To study the correlation between polyoma virus load and hemorrhagic cystitis after allogeneic stem cells transplantation for prevention of hemorrhagic cystitis...
  49. doi request reprint Photocytotoxicity of hypocrellin B (HB) was enhanced by liposomalization in vitro
    Zhixiang Zhou
    College of Life Science and Bioengineering, Beijing University of Technology, Beijing, China
    Int J Toxicol 30:174-80. 2011
    ..The encapsulation of HB influenced the cell death pathway by an increased rate of necrotic cells after irradiation versus free HB, and a Type II (singlet oxygen) mechanism was responsible for the photocytotoxicity...