Nicholas G Zaorsky

Summary

Publications

  1. doi request reprint Splenic irradiation for splenomegaly: A systematic review
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA Electronic address
    Cancer Treat Rev 53:47-52. 2016
  2. doi request reprint Comparison of outcomes and toxicities among radiation therapy treatment options for prostate cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA Electronic address
    Cancer Treat Rev 48:50-60. 2016
  3. doi request reprint Prostate Cancer Patients With Unmanaged Diabetes or Receiving Insulin Experience Inferior Outcomes and Toxicities After Treatment With Radiation Therapy
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA Electronic address
    Clin Genitourin Cancer . 2016
  4. pmc Men's health supplement use and outcomes in men receiving definitive intensity-modulated radiation therapy for localized prostate cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology
    Am J Clin Nutr 104:1583-1593. 2016
  5. ncbi request reprint Causes of death among cancer patients
    N G Zaorsky
    1 Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia PA, United States
    Ann Oncol . 2016
  6. doi request reprint What Are Medical Students in the United States Learning About Radiation Oncology? Results of a Multi-Institutional Survey
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania Electronic address
    Int J Radiat Oncol Biol Phys 94:235-42. 2016
  7. doi request reprint What is the ideal radiotherapy dose to treat prostate cancer? A meta-analysis of biologically equivalent dose escalation
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA Department of Radiation Oncology, Sidney Kimmel Cancer Center at Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA Electronic address
    Radiother Oncol 115:295-300. 2015
  8. doi request reprint High dose rate brachytherapy boost for prostate cancer: a systematic review
    Nicholas G Zaorsky
    Department of Radiation Oncology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Bodine Center for Cancer Treatment, 111 S 11th Street, Philadelphia, PA 19107, USA Electronic address
    Cancer Treat Rev 40:414-25. 2014
  9. pmc Systematic review of hypofractionated radiation therapy for prostate cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cancer Treat Rev 39:728-36. 2013
  10. doi request reprint Stereotactic body radiation therapy for prostate cancer: is the technology ready to be the standard of care?
    Nicholas G Zaorsky
    Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cancer Treat Rev 39:212-8. 2013

Collaborators

Detail Information

Publications36

  1. doi request reprint Splenic irradiation for splenomegaly: A systematic review
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA Electronic address
    Cancer Treat Rev 53:47-52. 2016
    ..In summary, SI is generally a safe and efficacious method for treating patients with symptomatic splenomegaly...
  2. doi request reprint Comparison of outcomes and toxicities among radiation therapy treatment options for prostate cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA Electronic address
    Cancer Treat Rev 48:50-60. 2016
    ....
  3. doi request reprint Prostate Cancer Patients With Unmanaged Diabetes or Receiving Insulin Experience Inferior Outcomes and Toxicities After Treatment With Radiation Therapy
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA Electronic address
    Clin Genitourin Cancer . 2016
    ..The purpose of the study was to determine the effect of type 2 diabetes mellitus (T2DM) on outcomes and toxicities among men with localized prostate cancer receiving definitive radiation therapy...
  4. pmc Men's health supplement use and outcomes in men receiving definitive intensity-modulated radiation therapy for localized prostate cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology
    Am J Clin Nutr 104:1583-1593. 2016
    ..Men's health supplements (MHSs), which we define as supplements that are specifically marketed with the terms men's health and prostate health (or similar permutations), are often mislabeled as having potential anticancer benefits...
  5. ncbi request reprint Causes of death among cancer patients
    N G Zaorsky
    1 Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia PA, United States
    Ann Oncol . 2016
    ..The purpose of our study was to characterize the causes of death among cancer patients as a function of objectives: (I) calendar year, (II) patient age, and (III) time after diagnosis...
  6. doi request reprint What Are Medical Students in the United States Learning About Radiation Oncology? Results of a Multi-Institutional Survey
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania Electronic address
    Int J Radiat Oncol Biol Phys 94:235-42. 2016
    ....
  7. doi request reprint What is the ideal radiotherapy dose to treat prostate cancer? A meta-analysis of biologically equivalent dose escalation
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA Department of Radiation Oncology, Sidney Kimmel Cancer Center at Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA Electronic address
    Radiother Oncol 115:295-300. 2015
    ..To determine if increasing the biologically equivalent dose (BED) via various radiation fractionation regimens is correlated with clinical outcomes or toxicities for prostate cancer...
  8. doi request reprint High dose rate brachytherapy boost for prostate cancer: a systematic review
    Nicholas G Zaorsky
    Department of Radiation Oncology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Bodine Center for Cancer Treatment, 111 S 11th Street, Philadelphia, PA 19107, USA Electronic address
    Cancer Treat Rev 40:414-25. 2014
    ..Comparative effectiveness research will help guide clinicians in selecting the most appropriate treatment option for individual patients based on risk-stratification, expected outcomes, toxicities, quality of life, and cost. ..
  9. pmc Systematic review of hypofractionated radiation therapy for prostate cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cancer Treat Rev 39:728-36. 2013
    ..High dose rate brachytherapy and stereotactic body radiation therapy (fraction size 3.5 Gy and greater) are alternative approaches to hypofractionation, but are beyond the scope of this report...
  10. doi request reprint Stereotactic body radiation therapy for prostate cancer: is the technology ready to be the standard of care?
    Nicholas G Zaorsky
    Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cancer Treat Rev 39:212-8. 2013
    ..Currently, SBRT regimens should only be used in the context of clinical trials...
  11. doi request reprint Evolution of advanced technologies in prostate cancer radiotherapy
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA
    Nat Rev Urol 10:565-79. 2013
    ....
  12. doi request reprint The dilemma of a rising prostate-specific antigen level after local therapy: what are our options?
    Nicholas G Zaorsky
    Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA 19107, USA
    Semin Oncol 40:322-36. 2013
    ..In this article we review the current and future factors that clinicians should consider in the diagnosis and treatment of recurrent prostate cancer. ..
  13. doi request reprint Combining theoretical potential and advanced technology in high-dose rate brachytherapy boost therapy for prostate cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology, Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, USA
    Expert Rev Med Devices 10:751-63. 2013
    ..HDR-BT boost is now a relatively well-established treatment modality for certain intermediate-risk and high-risk prostate cancer patients, though limitations exist in drawing conclusions from the currently published studies. ..
  14. ncbi request reprint Impact of Radiation Therapy Dose Escalation on Prostate Cancer Outcomes and Toxicities
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center Department of Pharmacology and Experimental Therapeutics, Division of Biostatistics Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pa Department of Radiation Oncology, Brigham and Women s Hospital, Boston, MA
    Am J Clin Oncol . 2016
    ....
  15. doi request reprint A paradigm shift from anatomic to functional and molecular imaging in the detection of recurrent prostate cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, PA, USA
    Future Oncol 10:457-74. 2014
    ..Further studies are needed to establish the role of imaging techniques for detection of cancer recurrence and clinical decision-making. ..
  16. pmc Impact of obesity on outcomes after definitive dose-escalated intensity-modulated radiotherapy for localized prostate cancer
    Lora S Wang
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania
    Cancer 121:3010-7. 2015
    ..The goal of the current study was to determine whether increasing BMI was associated with outcomes in men with localized CaP who were treated with dose-escalated RT...
  17. pmc A comparison of robotic arm versus gantry linear accelerator stereotactic body radiation therapy for prostate cancer
    Vladimir Avkshtol
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    Res Rep Urol 8:145-58. 2016
    ..Finally, SBRT (particularly on a gantry) may also be more cost-effective than conventionally fractionated external-beam radiation therapy. Randomized controlled trials of SBRT using both technologies are underway. ..
  18. doi request reprint Absence of Pathological Proof of Cancer Associated with Improved Outcomes in Early-Stage Lung Cancer
    Talha Shaikh
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania Electronic address
    J Thorac Oncol 11:1112-20. 2016
    ..The purpose of this study was to assess the trends in use of clinical diagnosis and its impact on treatment outcomes in patients receiving radiation therapy for early-stage lung cancer...
  19. ncbi request reprint Patient reported outcomes among treatment modalities for prostate cancer
    Matthew E Johnson
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
    Can J Urol 23:8535-8545. 2016
    ....
  20. pmc Assessment of the American Joint Committee on Cancer staging (sixth and seventh editions) for clinically localized prostate cancer treated with external beam radiotherapy and comparison with the National Comprehensive Cancer Network risk-stratification me
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
    Cancer 118:5535-43. 2012
    ....
  21. doi request reprint The Missing Pieces in Reporting of Randomized Controlled Trials of External Beam Radiation Therapy Dose Escalation for Prostate Cancer
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center Department of Radiation Oncology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pa Department of Radiation Oncology, Brigham and Women s Hospital, Boston, MA Department of Radiation Oncology, University of Virginia Health System, Charlottesville, VA
    Am J Clin Oncol 39:321-6. 2016
    ....
  22. ncbi request reprint Assessment of the American Joint Committee on Cancer (6th and 7th editions) for clinically localized prostate cancer and comparison to the National Comprehensive Cancer Network risk stratification method
    Mark K Buyyounouski
    Fox Chase Cancer Center, Philadelphia, PA
    J Clin Oncol 30:23. 2012
    ..23 Background: The purpose was to compare the prognostic value of the AJCC staging version 6 (v6), version 7 (v7), and the risk-stratification model of the NCCN...
  23. doi request reprint Importance of Surgical Margin Status in Ductal Carcinoma In Situ
    Talha Shaikh
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA
    Clin Breast Cancer 16:312-8. 2016
    ..The purpose of the study was to identify the effect of final surgical margin (SM) status and re-excision on outcomes in patients with ductal carcinoma in situ (DCIS) who underwent breast conservation therapy (BCT)...
  24. doi request reprint Large prostate gland size is not a contraindication to low-dose-rate brachytherapy for prostate adenocarcinoma
    Kosj Yamoah
    Department of Radiation Oncology, Kimmel Cancer Center and Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA Electronic address
    Brachytherapy 13:456-64. 2014
    ..We report biochemical control and toxicity after low-dose-rate PSI and compare outcomes according to the prostate size...
  25. doi request reprint Do theoretical potential and advanced technology justify the use of high-dose rate brachytherapy as monotherapy for prostate cancer?
    Nicholas G Zaorsky
    Department of Radiation Oncology Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, 19111, USA
    Expert Rev Anticancer Ther 14:39-50. 2014
    ..However, there are still certain limitations that preclude recommending HDR-BT monotherapy for prostate cancer outside the setting of a clinical trial. HDR-BT monotherapy should be considered experimental at present. ..
  26. ncbi request reprint ASTRO APEx® and RO-ILS™ are applicable to medical malpractice in radiation oncology
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    Future Oncol . 2016
    ..To analyze malpractice trials in radiation oncology and assess how ASTRO APEx® and RO-ILS™ apply to such cases...
  27. pmc Aspirin and statin nonuse associated with early biochemical failure after prostate radiation therapy
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
    Int J Radiat Oncol Biol Phys 84:e13-7. 2012
    ..To present the largest retrospective series investigating the effect of aspirin and statins, which are hypothesized to have antineoplastic properties, on biochemical failure (nadir plus 2 ng/mL) after prostate radiation therapy (RT)...
  28. doi request reprint The effect of ethnicity and sexual preference on prostate-cancer-related quality of life
    Nir Kleinmann
    Department of Urology, Thomas Jefferson University Hospital, 833 Chestnut Street, Suite 703, Philadelphia, PA 19107, USA
    Nat Rev Urol 9:258-65. 2012
    ..These parameters are often poorly documented and addressed by medical practitioners. Greater attention is needed to identify patients who are at increased risk of QOL reduction as a result of these factors...
  29. doi request reprint Multimodality therapy for patients with high-risk prostate cancer: current status and future directions
    Nicholas G Zaorsky
    Department of Radiation Oncology, Kimmel Cancer Center, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Semin Oncol 40:308-21. 2013
    ..In this article, we review the transforming world of multimodality therapy in high-risk prostate cancer. ..
  30. doi request reprint Optimizing patient positioning for intensity modulated radiation therapy in hippocampal-sparing whole brain radiation therapy
    Joshua Siglin
    Department of Radiation Oncology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania Electronic address
    Pract Radiat Oncol 4:378-83. 2014
    ..In this study, we sought to determine the optimal patient position to facilitate coplanar treatment planning and delivery of hippocampal-sparing WBRT using IMRT...
  31. doi request reprint Comparative effectiveness research for prostate cancer radiation therapy: current status and future directions
    Xinglei Shen
    Department of Radiation Oncology, Kimmel Cancer Center and Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
    Future Oncol 8:37-54. 2012
    ....
  32. pmc ALK inhibitor PF02341066 (crizotinib) increases sensitivity to radiation in non-small cell lung cancer expressing EML4-ALK
    Yunguang Sun
    Department of Radiation Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mol Cancer Ther 12:696-704. 2013
    ..Our findings indicate that PF02341066 acts as a radiation sensitizer in cells harboring the EML4-ALK fusion, providing a rationale for a clinical trial combining ALK inhibitor with radiation in the NSCLCs expressing ALK...
  33. doi request reprint Assessing the value of an optional radiation oncology clinical rotation during the core clerkships in medical school
    Nicholas G Zaorsky
    Department of Radiation Oncology, Jefferson Medical College, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA
    Int J Radiat Oncol Biol Phys 83:e465-9. 2012
    ..Few medical students are given proper clinical training in oncology, much less radiation oncology. We attempted to assess the value of adding a radiation oncology clinical rotation to the medical school curriculum...
  34. doi request reprint MicroRNA expression altered by diet: can food be medicinal?
    Joshua D Palmer
    Department of Radiation Oncology, Kimmel Cancer Center and Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, United States
    Ageing Res Rev 17:16-24. 2014
    ..These interventions have been linked, at a molecular level, to microRNAs. This review will summarize the role of various dietary strategies on the expression of several microRNA families. ..
  35. doi request reprint Chondrosarcoma of the hyoid bone: case report and review of current management options
    Isabella Zhang
    Department of Radiation Oncology Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania
    Head Neck 36:E65-72. 2014
    ..We reviewed the literature for diagnosis and management options of this exceptionally rare diagnosis...
  36. doi request reprint Oncology training programs: are we doing comparative effectiveness research justice?
    Nicholas G Zaorsky
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    J Comp Eff Res 2:573-82. 2013
    ..Upper level trainees who have reached milestones related to CER will be competitive applicants for research funding. ..