J Xu

Summary

Publications

  1. doi request reprint A new accurate assay for Coxsackievirus A 16 by fluorescence detection of isothermal RNA amplification
    Jin Xu
    Laboratory Medicine Center, Children s Hospital of Fudan University, Shanghai 201102, China Electronic address
    J Virol Methods 193:459-62. 2013
  2. pmc Expression of Toll-like receptors and their association with cytokine responses in peripheral blood mononuclear cells of children with acute rotavirus diarrhoea
    J Xu
    Pediatric Institute, Children s Hospital, Department of Pediatrics, Fudan University, Shanghai, China
    Clin Exp Immunol 144:376-81. 2006
  3. doi request reprint Molecular epidemiology of rotavirus infections among children hospitalized for acute gastroenteritis in Shanghai, China, 2001 through 2005
    Jin Xu
    Pediatric Institute, Children s Hospital, Fudan University, Shanghai 200032, China
    J Clin Virol 44:58-61. 2009
  4. doi request reprint Enhancement of mucosal and cellular immune response in mice by vaccination with respiratory syncytial virus DNA encapsulated with transfersome
    Jin Xu
    Pediatric Institute, Children s Hospital, Fudan University, Shanghai, China
    Viral Immunol 21:483-9. 2008
  5. doi request reprint Rotavirus and coxsackievirus infection activated different profiles of toll-like receptors and chemokines in intestinal epithelial cells
    Jin Xu
    Pediatric Institute, Children s Hospital, Fudan University, 183 Fenglin Road, 200032, Shanghai, China
    Inflamm Res 58:585-92. 2009
  6. doi request reprint Molecular epidemiology of norovirus infection among children with acute gastroenteritis in Shanghai, China, 2001-2005
    Jin Xu
    Pediatric Institute, Children s Hospital of Fudan University, Shanghai, China
    J Med Virol 81:1826-30. 2009
  7. ncbi request reprint MBD1 is an Epigenetic Regulator of KEAP1 in Pancreatic Cancer
    B Zhang
    Department of Oncology, Shanghai Medical College, Fudan University Pancreatic Cancer Institute, Fudan University, 270 DongAn Road, Shanghai 200032, China
    Curr Mol Med 16:404-11. 2016
  8. ncbi request reprint miR-1247 is correlated with prognosis of pancreatic cancer and inhibits cell proliferation by targeting neuropilins
    S Shi
    X Yu No 270, Dong an Road, Xuhui District, Shanghai, 200032, P R China
    Curr Mol Med 14:316-27. 2014
  9. ncbi request reprint VEGF Promotes Glycolysis in Pancreatic Cancer via HIF1α Up-Regulation
    S Shi
    Department of Oncology, Shanghai Medical College, Fudan University Pancreatic Cancer Institute, Fudan University, 270 DongAn Road, Shanghai 200032, China
    Curr Mol Med 16:394-403. 2016
  10. doi request reprint Infiltrating immune cells and gene mutations in pancreatic ductal adenocarcinoma
    W Q Wang
    Department of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Centre, Shanghai, China
    Br J Surg 103:1189-99. 2016

Collaborators

  • C Liu
  • L Liu
  • X Yu
  • Y Qin
  • Y Zhang
  • X Zhang
  • H Cheng
  • L Xu
  • Y Xu
  • J Wang
  • H Wang
  • Y Wang
  • Y Yang
  • Z Li
  • B Zhang
  • S Shi
  • J Sun
  • J E Moore
  • B C Millar
  • W Zhang
  • Z Lin
  • L Liang
  • M Xu
  • X Liu
  • J Long
  • H An
  • G Ding
  • S Lu
  • M Watabe
  • Y Sun
  • Y Zhong
  • J I Levin
  • M H Zheng
  • H Chen
  • Y Huang
  • Y Ji
  • W Xu
  • J R Rao
  • D Zhang
  • X Huang
  • W Q Wang
  • R McMullan
  • Y Sunnassee
  • D Lin
  • Y Chang
  • H Liu
  • Y Liu
  • Y Zhu
  • W Liu
  • D Zhu
  • X Feng
  • M Duan
  • Y Lu
  • C Y Hsu
  • Y Dong
  • L Chen
  • A Zhang
  • F Xu
  • W Yao
  • F W Bai
  • M Yu
  • S Lin
  • B Liu
  • Z Zhang
  • D Chen
  • J Li
  • J Fan
  • L Ren
  • H Chang
  • S L Zheng
  • L Wang
  • G Jin
  • S Chen
  • M Dong
  • Q M Gong
  • Z Zhou
  • Y Shi
  • Y Tan
  • Y Hou
  • P Wang
  • C J Lowery
  • K Li
  • L Li
  • G M Kim
  • P Yan
  • T Kirchberger
  • J S Skotnicki
  • L M Laakso
  • M Du
  • J M Chen

Detail Information

Publications124 found, 100 shown here

  1. doi request reprint A new accurate assay for Coxsackievirus A 16 by fluorescence detection of isothermal RNA amplification
    Jin Xu
    Laboratory Medicine Center, Children s Hospital of Fudan University, Shanghai 201102, China Electronic address
    J Virol Methods 193:459-62. 2013
    ..2%, respectively. These findings indicate that SAT-CA16 is a rapid and reliable method for detecting CA16. ..
  2. pmc Expression of Toll-like receptors and their association with cytokine responses in peripheral blood mononuclear cells of children with acute rotavirus diarrhoea
    J Xu
    Pediatric Institute, Children s Hospital, Department of Pediatrics, Fudan University, Shanghai, China
    Clin Exp Immunol 144:376-81. 2006
    ..Our results suggest that multiple TLRs may modulate the immune response in the acute phase of rotavirus infection and play a role in the activation of IFN-gamma...
  3. doi request reprint Molecular epidemiology of rotavirus infections among children hospitalized for acute gastroenteritis in Shanghai, China, 2001 through 2005
    Jin Xu
    Pediatric Institute, Children s Hospital, Fudan University, Shanghai 200032, China
    J Clin Virol 44:58-61. 2009
    ..Rotavirus is the most common cause of severe diarrhea in children in the world. Knowing the prevalence and genotypes of these infections is important for implementing vaccination programs...
  4. doi request reprint Enhancement of mucosal and cellular immune response in mice by vaccination with respiratory syncytial virus DNA encapsulated with transfersome
    Jin Xu
    Pediatric Institute, Children s Hospital, Fudan University, Shanghai, China
    Viral Immunol 21:483-9. 2008
    ..Immunization with transfersome encapsulated F gene encoding DNA induces mucosal and cellular immune responses in mice that appear to produce protective immunity against respiratory syncytial virus...
  5. doi request reprint Rotavirus and coxsackievirus infection activated different profiles of toll-like receptors and chemokines in intestinal epithelial cells
    Jin Xu
    Pediatric Institute, Children s Hospital, Fudan University, 183 Fenglin Road, 200032, Shanghai, China
    Inflamm Res 58:585-92. 2009
    ..To understand the inflammatory-immune response in intestinal epithelial cells after infection of rotavirus and coxsackievirus B3...
  6. doi request reprint Molecular epidemiology of norovirus infection among children with acute gastroenteritis in Shanghai, China, 2001-2005
    Jin Xu
    Pediatric Institute, Children s Hospital of Fudan University, Shanghai, China
    J Med Virol 81:1826-30. 2009
    ..This study demonstrated the impact of norovirus infection causing acute gastroenteritis in hospitalized children and the importance of vaccination against norovirus diarrhea in Shanghai, China...
  7. ncbi request reprint MBD1 is an Epigenetic Regulator of KEAP1 in Pancreatic Cancer
    B Zhang
    Department of Oncology, Shanghai Medical College, Fudan University Pancreatic Cancer Institute, Fudan University, 270 DongAn Road, Shanghai 200032, China
    Curr Mol Med 16:404-11. 2016
    ..However, the role of MBD1 with antioxidant response and its association with KEAP1 has never been reported before and remains unclear...
  8. ncbi request reprint miR-1247 is correlated with prognosis of pancreatic cancer and inhibits cell proliferation by targeting neuropilins
    S Shi
    X Yu No 270, Dong an Road, Xuhui District, Shanghai, 200032, P R China
    Curr Mol Med 14:316-27. 2014
    ..These findings suggest that miR-1247, a novel tumor suppressor, can act as a potential biomarker and therapeutic agent for pancreatic cancer. ..
  9. ncbi request reprint VEGF Promotes Glycolysis in Pancreatic Cancer via HIF1α Up-Regulation
    S Shi
    Department of Oncology, Shanghai Medical College, Fudan University Pancreatic Cancer Institute, Fudan University, 270 DongAn Road, Shanghai 200032, China
    Curr Mol Med 16:394-403. 2016
    ..Tumor cellderived VEGF promotes angiogenesis and tumor progression. However, the role of VEGF in glucose metabolism remains unclear...
  10. doi request reprint Infiltrating immune cells and gene mutations in pancreatic ductal adenocarcinoma
    W Q Wang
    Department of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Centre, Shanghai, China
    Br J Surg 103:1189-99. 2016
    ....
  11. ncbi request reprint High Expression of Human Leukocyte Antigen-G is Associated with a Poor Prognosis in Patients with PDAC
    Y F Xu
    Department of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, No 270 Dongan Road, Shanghai 200032, China
    Curr Mol Med 15:360-7. 2015
    ..In conclusion, tumor-derived HLA-G may indicate the mechanism of immune escape and impaired PDAC clinical outcome, especially in early-stage patients, which may also be a potential therapeutic target. ..
  12. doi request reprint Cavin-1 is essential for the tumor-promoting effect of caveolin-1 and enhances its prognostic potency in pancreatic cancer
    L Liu
    Pancreatic Cancer Institute, Fudan University Department of Pancreatic and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
    Oncogene 33:2728-36. 2014
    ....
  13. ncbi request reprint Profilin 1 potentiates apoptosis induced by staurosporine in cancer cells
    W Yao
    Department of Pancreas and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, P R China
    Curr Mol Med 13:417-28. 2013
    ..In addition, p53R273H abrogating DNA binding was found to play a major role in the Pfn1- sensitized apoptosis through a transactivation-independent and cytosolic activity...
  14. ncbi request reprint A phase II study of cetuximab (Cetuximab) with cisplatin and capecitabine (Xeloda) as 1st line treatment in advanced gastric cancer
    X Zhang
    Peking University School of Oncology, Bejing, China Cancer Center, 307 Hospital, AMMS, Beijing, China Cancer Institute and Hospital, CAMS, Beijing, China The Affliated Hospital of Qingdao University, Qingdao, Shandong, Province, China, China First Affliated Hospital of Zhejiang University, Hangzhou Zhejiang, China Tumor Hospital, affliated to Harbin Medical School, Haerbin, Heilongjiang Province, China Changzheng Hospital, Second Military Medical School, Shanghai, China
    J Clin Oncol 26:15663. 2008
    ..The aim of this single arm, open, multicenter phase II study is to observe the efficacy and safety of Cetuximab combined with XP(cisplatin plus capecitabine) in advanced gastric cancer as the first line therapy...
  15. ncbi request reprint Preoperative hepatic and regional arterial chemotherapy in the prevention of liver metastasis after colorectal cancer surgery
    J Xu
    Zhongshan Hospital, Fudan University, Shanghai, China
    J Clin Oncol 27:4090. 2009
    ..4090 Background: To investigate whether preoperative hepatic and regional arterial chemotherapy are able to prevent liver metastasis and improve overall survival in patients receiving curative colorectal cancer resection...
  16. doi request reprint Transgenic characterization of two testis-specific promoters in the silkworm, Bombyx mori
    J Xu
    Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China University of Chinese Academy of Sciences, Beijing, China
    Insect Mol Biol 24:183-90. 2015
    ..Identification of these testis-specific promoters not only contributes to a better understanding of testis-specific gene function in insects, but also has potential applications in sterile insect techniques for pest management...
  17. pmc Systemic inflammation score predicts postoperative prognosis of patients with clear-cell renal cell carcinoma
    Y Chang
    Department of Urology, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, China
    Br J Cancer 113:626-33. 2015
    ..We developed a novel systemic inflammation score (SIS) based on preoperative serum albumin and lymphocyte-to-monocyte ratio (LMR), and examined its prognostic value for patients with clear-cell renal cell carcinoma (ccRCC) after surgery...
  18. ncbi request reprint MicroRNA-34b inhibits pancreatic cancer metastasis through repressing Smad3
    C Liu
    Department of Pancreatic and Hepatobiliary Surgery, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
    Curr Mol Med 13:467-78. 2013
    ..Our findings indicate that miR-34b acts as a tumor metastasis suppressor through negatively modulating Smad3, which may provide a potential therapeutic strategy for pancreatic cancer...
  19. ncbi request reprint Stathmin, interacting with Nf-κB, promotes tumor growth and predicts poor prognosis of pancreatic cancer
    Y Lu
    No 270, Dong an Road, Xuhui District, Shanghai, 200032, P R China
    Curr Mol Med 14:328-39. 2014
    ....
  20. ncbi request reprint Study on malignancy, staging, and grading for gastrointestinal stromal tumors
    Y Hou
    Zhongshan Hospital, Fudan University, Shanghai, China Cancer Hospital, Shanghai, China
    J Clin Oncol 26:21521. 2008
    ..Although risk stratification was proposed by the NIH criteria according to tumor size and mitoses, limitations of the criteria exist, and better risk factors are needed...
  21. ncbi request reprint A novel mutant-enriched liquidchip for detection of circulating EGFR mutations in advanced non-small cell lung cancer patients
    S Lu
    Shanghai Chest Hospital, Shanghai, China SurExam Biotech, Science City, Guangzhou, 510663, Guangzhou, China
    J Clin Oncol 27:e14526. 2009
    ....
  22. doi request reprint Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity
    D Zhang
    Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
    Oncogene . 2016
    ..Oncogene advance online publication, 19 December 2016; doi:10.1038/onc.2016.446...
  23. doi request reprint IGFBP-3 A-202C and C2133G polymorphisms and colorectal cancer risk: a meta-analysis of case-control studies
    J Xu
    Department of General Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China
    Genet Mol Res 14:3370-86. 2015
    ..The G variant of the IGFBP-3 C2133G polymorphism may serve as a useful biomarker for predicting the risk of colorectal cancer. ..
  24. doi request reprint Octreotide for the treatment of systemic lupus erythematosus: clinical effects and an in vitro study on its therapeutic mechanism
    Y Zhang
    Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China
    Lupus 20:1172-81. 2011
    ..OCT inhibited PBMC proliferation and PBMC secretion of IL-6, IL-10 and IFN-γ stimulated by GH. Treatment of patients with OCT resulted in clinical improvement in SLE...
  25. ncbi request reprint Identification of rice black streaked dwarf virus in different cereal crops with dwarfing symptoms in China
    F W Bai
    Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, PR China
    Acta Virol 45:335-9. 2001
    ..The phylogenetic analysis indicated that the Chinese isolates that infect rice, maize, wheat and sorghum and cause similar symptoms could represent the same virus species, RBSDV...
  26. ncbi request reprint CT virtual endoscopy of the auditory ossicular chain: clinical applications
    D Wang
    Department of CT and MRI, Air Force General Hospital, Beijing 100036, China
    Chin Med J (Engl) 114:1015-8. 2001
    ..To evaluate the clinical applications and limitations of CT virtual endoscopy (CTVE) in the auditory ossicular chain...
  27. ncbi request reprint Large dose ketamine inhibits lipopolysaccharide-induced acute lung injury in rats
    J Yang
    School of Medicine, Nanjing University and Department of Anesthesiology, Jinling Hospital, 305 East Zhongshan Road, Nanjing 210002, China
    Inflamm Res 54:133-7. 2005
    ..Our study was designed to investigate the effect of ketamine on the endotoxin-induced acute lung injury in vivo...
  28. doi request reprint Multidrug resistant gram-negative bacilli as predominant bacteremic pathogens in liver transplant recipients
    S H Shi
    Department of Hepatobiliary Surgery, Center of Liver Transplantation, Zhejiang University, Hangzhou, China
    Transpl Infect Dis 11:405-12. 2009
    ..The aim of this study was to investigate bacteremic incidence, pathogenic spectrum, risk factors for bacteremia due to multidrug resistant (MDR) gram-negative bacilli, and its impact on mortality after LT...
  29. doi request reprint Occult hepatocellular carcinoma: a case report of a special icteric-type hepatoma and literature review
    H Chang
    Department of Hepatobiliary and Pancreatic Surgery, Shandong Provincial Hospital, Shandong University School of Medicine, Shandong, China
    Eur J Cancer Care (Engl) 19:690-3. 2010
    ..With respect to improving prognosis, a curative resection of primary HCC and tumour thrombi was suggested on the basis of performing an intensive post-operative monitoring for early detection of primary liver lesion...
  30. doi request reprint Assessing facilitative responses to a nurse shrub at the community level: the example of Potentilla fruticosa in a sub-alpine grassland of northwest China
    J Xu
    MOE Key Laboratory of Arid and Grassland Ecology, School of Life Science, Lanzhou University, Lanzhou, China
    Plant Biol (Stuttg) 12:780-7. 2010
    ..Assessing interactive responses at the community level is likely to provide a useful tool to better understand the role of biotic interactions in community responses to environmental changes...
  31. doi request reprint Somatic gene copy number alterations in colorectal cancer: new quest for cancer drivers and biomarkers
    H Wang
    State Key Laboratory for Oncogenes and Related Genes Key Laboratory of Gastroenterology and Hepatology, Ministry of Health Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai Cancer Institute, Shanghai Institute of Digestive Disease, Shanghai, China
    Oncogene 35:2011-9. 2016
    ..In this view, we systematically discuss the frequent CNAs in CRC, focusing on functional genes that have potential diagnostic, prognostic and therapeutic significance...
  32. ncbi request reprint Human Adipose-Derived Stem Cells Delay Retinal Degeneration in Royal College of Surgeons Rats Through Anti-Apoptotic and VEGF-Mediated Neuroprotective Effects
    Z Li
    Department of Ophthalmology of Shanghai Tenth People s Hospital, and Tongji Eye Institute, Tongji University School of Medicine, 301 Middle YanChang Road, Shanghai, 200072, China
    Curr Mol Med 16:553-66. 2016
    ..Stem cell therapy is a promising therapeutic approach for retinal degeneration (RD). Our study investigated the effects of human adipose derived stem cell (hADSCs) on Royal College of Surgeons (RCS) rats...
  33. pmc Polycomb-mediated loss of microRNA let-7c determines inflammatory macrophage polarization via PAK1-dependent NF-κB pathway
    W Zhang
    Department of Immunology, School of Basic Medical Sciences, Shanghai Medical College of Fudan University, Shanghai 200032, China
    Cell Death Differ 22:287-97. 2015
    ..PAK1, therefore, is an essential controller of inflammatory macrophage polarization, regulating immune responses against pathogenic stimuli. ..
  34. ncbi request reprint Kinetics of serological responses in influenza A(H7N9)-infected patients correlate with clinical outcome in China, 2013
    A Zhang
    Shanghai Public Health Clinical Center and Institutes of Biomedical Sciences, Key Laboratory of Medical Molecular Virology of Ministry of Education Health, Shanghai Medical College, Fudan University, Shanghai, China
    Euro Surveill 18:20657. 2013
    ..007). Early and rapid induction of Nab was correlated significantly with better clinical outcome...
  35. pmc High CXC chemokine receptor 4 expression is an adverse prognostic factor in patients with clear-cell renal cell carcinoma
    H An
    Department of Urology, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai 200032, China
    Br J Cancer 110:2261-8. 2014
    ..The aim of this study was to determine the prognostic value of CXCR4 expression in patients with clear-cell renal cell carcinoma (ccRCC)...
  36. ncbi request reprint Effects and mechanisms of somatostatin analogs on apoptosis of pancreatic acinar cells in acute pancreatitis in mice
    Y Yuan
    Department of Gastroenterology, Ruijin Hospital, Shanghai Second Medical University, Shanghai, China
    J Gastroenterol Hepatol 16:683-8. 2001
    ..To investigate the effects of somatostatin analogs (SSa) on apoptosis of pancreatic acinar cells and apoptosis-regulated gene bax, and p53 in treating acute pancreatitis in mice...
  37. doi request reprint DNA methylation levels of imprinted and nonimprinted genes DMRs associated with defective human spermatozoa
    J Xu
    Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Andrologia 48:939-947. 2016
    ..This study provides the potential association between low sperm motility infertile men and the aberrant DNA methylation of MEST, LINE-1, GNAS and FAM50B DMRs...
  38. pmc Gain of function of mutant p53: R282W on the peak?
    Y Zhang
    State Key Laboratory for Oncogenes and Related Genes, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Cancer Institute, Shanghai Institute of Digestive Disease, Shanghai, China
    Oncogenesis 5:e196. 2016
    ..The quest for mechanistic insights into the unique GOF effects of R282W mutation would further our understanding of the biology of mutant proteins in cancers, and enforce the development of more effective targeted therapies. ..
  39. ncbi request reprint Detection of EGFR mutations with mutation-specific antibodies in primary lesions of non-small cell lung cancer
    X Zhang
    Guangdong Lung Cancer Institute, Medical Research Center of Guangdong General Hospital, Guangzhou, China Innovation Center China of AstraZeneca, Shanghai, China Guangdong Lung Cancer Institute, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China Guangdong Lung Cancer Institute, Medical Research Center of Guangdong General Hospital GAMS, Guangzhou, China
    J Clin Oncol 29:7035. 2011
    ..Here we evaluated the utility of EGFR mutation-specific antibodies in primary tumors for screening of EGFR-mutant NSCLC patients in comparison with a sequencing method...
  40. ncbi request reprint A randomized, double-blind, multicenter, phase II, three-arm, placebo-control study of apatinib as third-line treatment in patients with metastatic gastric carcinoma
    J Li
    Fudan University Cancer Center, Shanghai, China Nanjing Bayi Hospital, Nanjing, China Cancer Center, 307 Hospital, Academy of Military Medical Science, Beijing, China The First Affiliated Hospital of Nanchang University, Nanchang, China Heilongjiang Provincial Cancer Hospital, Harbin, China The First Affiliated Hospital of Anhui Medical University, Hefei, China Cancer Hospital of Gansu Province, Lanzhou, China Shanghai First People s Hospital, Shanghai Jiaotong University, Shanghai, China Department of Medical Oncology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China Jilin Province Cancer Hospital, Changchun, China Shangdong Tumor Hospital, Jinan, China Department of Oncology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China First Affiliated Hospital of Soochow University, Suzhou, China
    J Clin Oncol 29:4019. 2011
    ..The objective of this study was to evaluate the efficacy and safety of apatinib in patients with advanced or metastatic gastric cancer after failure of two lines of chemotherapy...
  41. doi request reprint Tag SNPs for HLA-B alleles that are associated with drug response and disease risk in the Chinese Han population
    X Liu
    State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
    Pharmacogenomics J 15:467-72. 2015
    ..These results were confirmed in 500 additional Chinese Han subjects. If confirmed in independent studies, these tag SNPs could be used as a reliable, simple and cost-effective alternative for genotyping a subset of HLA-B alleles...
  42. pmc Transcription activator-like effector nuclease (TALEN)-mediated female-specific sterility in the silkworm, Bombyx mori
    J Xu
    Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China University of Chinese Academy of Sciences, Beijing, China
    Insect Mol Biol 23:800-7. 2014
    ..The current somatic TALEN technologies provide a promising approach for future insect functional genetics, thus providing the basis for the development of attractive genetic alternatives for insect population management. ..
  43. pmc Detection of acute cerebral hemorrhage in rabbits by magnetic induction
    J Sun
    College of Biomedical Engineering and Medical Imaging, Third Military Medical University, Chongqing, China, College of Biomedical Engineering and Medical Imaging, Third Military Medical University, Chongqing, China
    Braz J Med Biol Res 47:144-50. 2014
    ..The MIPS was significantly related to the intracranial pressure. This observation suggests that the method could be valuable for detecting early warning signs in emergency medicine and critical care units. ..
  44. pmc Inhibition of 12/15-lipoxygenase by baicalein induces microglia PPARβ/δ: a potential therapeutic role for CNS autoimmune disease
    J Xu
    Shanghai Institute of Immunology, Institutes of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Cell Death Dis 4:e569. 2013
    ..Our findings indicate that inhibition of 12/15-LO induces PPARβ/δ, demonstrating important regulatory properties of 12/15-LO in CNS inflammation. This reveals potential therapeutic applications for MS...
  45. ncbi request reprint Modification of the neurotrophin-3 gene promotes cholinergic neuronal differentiation and survival of neural stem cells derived from rat embryonic spinal cord in vitro and in vivo
    S Lin
    Department of Orthopaedics, Shanghai Sixth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    J Int Med Res 40:1449-58. 2012
    ..To investigate the effects of the neurotrophin-3 (NTF3) gene on the survival and differentiation of neural stem cells (NSCs) in vitro and in vivo...
  46. doi request reprint Association analysis of BANK1 gene with psoriasis in Southern Han Chinese
    X Zhang
    Shanghai Medical College, Fudan University, Shanghai, China
    Int J Immunogenet 38:507-12. 2011
    ..38, 95% CI: 1.05-1.81, P = 0.0203). Overall, our result indicates that polymorphism in BANK1 is associated with susceptibility to psoriasis in Southern Han Chinese...
  47. ncbi request reprint [Expression of matrix metalloproteinase-2 in rat pulmonary fibrosis]
    H Wu
    Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
    Zhonghua Bing Li Xue Za Zhi 30:452-5. 2001
    ..CONCLUSIONS: Over expression of MMP(2) in pulmonary tissue may be an important factor in the initiation of pulmonary fibrogenesis...
  48. pmc Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo
    H Wang
    Department of Orthopaedics, Shanghai First People s Hospital, Shanghai Jiao Tong University, Shanghai, China
    Cell Death Dis 7:e2247. 2016
    ..In conclusion, erianin induced cell cycle G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human OS. In light of these results, erianin may be a promising agent for anticancer therapy against OS. ..
  49. doi request reprint [The surgical management of giant intracranial vestibular schwannoma via retrosigmoid approach: a retrospective review of 657 cases]
    X Huang
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China
    Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 51:401-7. 2016
    ..To discuss the surgical technique and common complications from the microsurgical treatment of giant intracranial vestibular schwannoma via suboccipital retrosigmoid approach and to propose strategies for minimizing such complications...
  50. ncbi request reprint Phase I study of chidamide (CS055/HBI-8000), a novel histone deacetylase inhibitor, in patients with advanced solid tumors and lymphomas
    M Dong
    Cancer Institute and Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China Chipscreen Biosciences Ltd, Shenzhen, China HUYA Bioscience International, San Diego, CA Tigermed Consulting Ltd, Shanghai, China Lab of DMPK, Institute of Transfusion Medicine, Beijing, China
    J Clin Oncol 27:3529. 2009
    ..This Phase I study evaluated the safety and tolerability of chidamide in patients (pts) with advanced solid tumors and lymphomas...
  51. ncbi request reprint Analysis of signal pathway activation in hepatocellular carcinoma: Association with clinical outcomes to sorafenib in Chinese patients
    Y Ji
    Zhongshan Hospital, Shanghai, China
    J Clin Oncol 27:e15529. 2009
    ..Greater understanding of the cellular response to sorafenib is needed to tailor targeted therapy for individual patients and identify those more likely to benefit...
  52. ncbi request reprint Phase I study on safety and pharmacokinetics of sulfatinib, a selective VEGFR/FGFR dual inhibitor, in Chinese patients with advanced solid tumors
    J Xu
    Cancer Center, 307 Hospital, Academy of Military Medical Science, Beijing, China Hutchison MediPharma Ltd, Shanghai, China Peking University 3rd Hospital, Beijing, China Beijing University Hospital, Beijing, China
    J Clin Oncol 29:e13558. 2011
    ..It demonstrated potent in vivo inhibitory effects on a variety of human tumor xenografts. The current study was designed to evaluate safety and tolerability, pharmacokinetics, and preliminary anti-tumor activity of sulfatinib...
  53. doi request reprint Gastric cancer and gene copy number variation: emerging cancer drivers for targeted therapy
    L Liang
    State Key Laboratory for Oncogenes and Related Genes Key Laboratory of Gastroenterology and Hepatology, Ministry of Health Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai Cancer Institute, Shanghai Institute of Digestive Disease, Shanghai, China
    Oncogene 35:1475-82. 2016
    ..In this review, we discuss the recent CNV discoveries that shed light on the molecular pathogenesis of GC, with a specific emphasis on CNVs that display diagnostic, prognostic or therapeutic significances in GC. ..
  54. pmc SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment
    Y Sun
    Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences SIBS, Chinese Academy of Sciences CAS and Shanghai Jiaotong University School of Medicine SJTUSM, Shanghai, China
    Oncogene 35:4321-34. 2016
    ....
  55. doi request reprint Mutation of the rice ASL2 gene encoding plastid ribosomal protein L21 causes chloroplast developmental defects and seedling death
    D Lin
    Development Center of Plant Germplasm Resources, College of Life and Environment Sciences, Shanghai Normal University, Shanghai, China
    Plant Biol (Stuttg) 17:599-607. 2015
    ..Collectively, the absence of functional ASL2 caused chloroplast developmental defects and seedling death. This report establishes the important role of RPL21c in chloroplast development in rice. ..
  56. doi request reprint Preliminary results for the use of knee mega-endoprosthesis in the treatment of musculoskeletal complications of haemophilia
    Y Sunnassee
    Department of Orthopedics, Shanghai Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Institute of Orthopedics and Traumatology, Shanghai, China
    Haemophilia 21:258-65. 2015
    ....
  57. doi request reprint HIF1A gene Pro582Ser polymorphism and susceptibility to digestive tract cancers: a meta-analysis of case-control studies
    J Xu
    Department of General Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, China
    Genet Mol Res 13:5732-44. 2014
    ..However, similar association was not observed in Caucasian populations. In conclusion, our findings suggest that HIF1A Pro582Ser polymorphism may contribute to the risk of digestive tract cancers, especially in Asian populations...
  58. doi request reprint Self-declared sensitive skin in China: a community-based study in three top metropolises
    F Xu
    Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China Peking Union Medical College Hospital, Beijing, 100730, P R China The Third Affiliated Hospital of Sun Yat sen University, Guangzhou, 510630, P R China Pierre Fabre Dermo Cosmetique China, Shanghai, 200001, P R China Public Health and Quality of Life Department, Eau Thermale Avène, France
    J Eur Acad Dermatol Venereol 27:370-5. 2013
    ..To investigate the prevalence and the factors related to the sensitive skin in China...
  59. ncbi request reprint Up-regulation of MBD1 promotes pancreatic cancer cell epithelial-mesenchymal transition and invasion by epigenetic down-regulation of E-cadherin
    J Xu
    Department of Pancreas and Hepatobiliary Surgery, Fudan University Shanghai Cancer Center, Fudan University, 270 Dong An Road, Shanghai 200032, China
    Curr Mol Med 13:387-400. 2013
    ..Taken together, the results of our study revealed a novel function of MBD1 in PC invasion and metastasis by providing a molecular mechanism underlying MBD1-promoted EMT. Thus MBD1 may serve as a potential therapeutic target for PC...
  60. doi request reprint The results of surgery for colorectal hepatic metastases following expansion of the indications in 2005
    Y Zhong
    Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China
    Colorectal Dis 15:e429-34. 2013
    ..Safety and survival were investigated in patients treated according to expanded surgical indications for colorectal hepatic metastases...
  61. doi request reprint [Association between the myeloperoxidase gene polymorphisms and the susceptibility to prostate cancer: a case-control study in a Chinese population]
    G Ding
    Department of Urology, Huashan Hospital, Fudan University, Shanghai, China
    Actas Urol Esp 37:79-82. 2013
    ..Our study aimed to evaluate the association between the genetic polymorphisms and the risk of prostate cancer...
  62. ncbi request reprint An epidemiological survey on neonatal jaundice in China
    G Ding
    Department of Pediatrics, Peking Union Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
    Chin Med J (Engl) 114:344-7. 2001
    ..It is suggested that the diagnostic criteria for neonatal hyperbilirubinemia in China should be strict...
  63. ncbi request reprint Phylogenetic analysis of intestinal bacteria in the Chinese mitten crab (Eriocheir sinensis)
    K Li
    Laboratory of Molecular Microbial Ecology and Ecogenomics, College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China
    J Appl Microbiol 103:675-82. 2007
    ..To identify the dominant intestinal bacteria in the Chinese mitten crab, and to investigate the differences in the intestinal bacteria between pond-raised and wild crabs...
  64. doi request reprint Endoscopic decompression using a transanal drainage tube for acute obstruction of the rectum and left colon as a bridge to curative surgery
    M Xu
    Department of Endoscopic center, Zhongshan Hospital, Fudan University Medical Center, Shanghai, China
    Colorectal Dis 11:405-9. 2009
    ..The aim of this study was to clarify the usefulness of the management of acute left colon and rectum obstruction because of colorectal carcinoma using a transanal ileus drainage tube before curative surgery...
  65. ncbi request reprint Association study of IFNAR2 and IL10RB genes with the susceptibility and interferon response in HBV infection
    Q M Gong
    Department of Infectious Diseases, School of Medicine, Shanghai Jiaotong University, Ruijin Hospital, Shanghai, China
    J Viral Hepat 16:674-80. 2009
    ..040). This study suggests that IFNAR2 may play an important role in determining IFN response and clinical phenotypes of HBV infection in the Chinese Han population...
  66. ncbi request reprint Selection of phage-display peptides that bind specifically to the outer coat protein of Rice black streaked dwarf virus
    F W Bai
    Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, PR China
    Acta Virol 46:85-90. 2002
    ..Summing up, as these peptides showed a high specificity and sensitivity and diagnostic potential for RBSDV, they may represent the basis of a novel strategy for development of resistance to RBSDV...
  67. ncbi request reprint Influence of hydroxyethyl starch 130/0.4 in pulmonary neutrophil recruitment and acute lung injury during polymicrobial sepsis in rats
    X Feng
    Department of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China
    Acta Anaesthesiol Scand 50:1081-8. 2006
    ..This study was designed to explore the effects of hydroxyethyl starch (HES) 130/0.4 (a novel plasma substitute) on pulmonary neutrophil recruitment and associated ALI in a rat sepsis model induced by cecal ligation and puncture (CLP)...
  68. ncbi request reprint Effects of ketamine on pulmonary TLR4 expression and NF-kappa-B activation during endotoxemia in rats
    M Yu
    Department of Anesthesiology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China
    Methods Find Exp Clin Pharmacol 29:395-9. 2007
    ..The present study revealed that ketamine could inhibit pulmonary NF-kappa-B activity during endotoxemia in rats, and this antiinflammatory effect possibly acts through suppressing TLR4 expression...
  69. doi request reprint Mesenchymal stem cell-based angiopoietin-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice
    J Xu
    Department of Pulmonary Medicine, Zhongshan Hospital, State Key Laboratory of Genetic Engineering, Shanghai Medical College, Fudan University, People s Republic of China
    J Pathol 214:472-81. 2008
    ..These results suggest that MSCs and Ang1 have a synergistic role in the treatment of LPS-induced lung injury. MSC-based Ang1 gene therapy may be developed as a potential novel strategy for the treatment of acute lung injury...
  70. ncbi request reprint Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17
    L C Brody
    National Center for Human Genome Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genomics 25:238-47. 1995
    ..In addition, 39 putative exons and 14 expressed sequence tags have been identified and mapped to individual cosmids. This transcript map provides a detailed description of gene organization for this region of the genome...
  71. ncbi request reprint Cloning and expression of glucocorticoid-induced genes in fetal rat lung fibroblasts. Transforming growth factor-beta 3
    J Wang
    Department of Paediatrics, Hospital for Sick Children Research Institute, University of Toronto, Ontario, Canada
    J Biol Chem 270:2722-8. 1995
    ..These data suggest that glucocorticoids may mediate their stimulatory effect on lung maturation by inducing TGF beta 3 expression in fetal lung fibroblasts...
  72. pmc Genomic structure and cloned cDNAs predict that four variants in the kinase domain of serine/threonine kinase receptors arise by alternative splicing and poly(A) addition
    J Xu
    W Alton Jones Cell Science Center, Inc, Lake Placid, NY 12946
    Proc Natl Acad Sci U S A 91:7957-61. 1994
    ....
  73. ncbi request reprint A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor beta, or bone morphogenic factor
    K Matsuzaki
    W Alton Jones Cell Science Center, Inc, Lake Placid, New York 12946
    J Biol Chem 268:12719-23. 1993
    ..The expression pattern and lack of binding to prototypic members of the TGF-beta 1-5 branch of the TGF-beta superfamily suggests that SKR1 is potentially a receptor for a new member of the TGF-beta branch of the ligand superfamily...
  74. ncbi request reprint The expression of the Drosophila awd gene during normal development and in neoplastic brain tumors caused by lgl mutations
    L Timmons
    Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218
    Dev Biol 158:364-79. 1993
    ..Using the same awd reporter gene as a marker of donor cells, we have confirmed the invasiveness of lgl-induced neuroblastomas...
  75. pmc Impaired primary T cell responses in L-selectin-deficient mice
    J Xu
    Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    J Exp Med 183:589-98. 1996
    ..L-selectin does not appear to be rate limiting for the events leading to antigen-driven neutrophil recruitment, since normal DTH responses are obtained at late time points after immunization...
  76. ncbi request reprint Rearrangement and reactivation of the myelin basic protein locus in myelin-deficient (mld) mouse brain
    Y Sun
    Neuroscience Program, University of Connecticut Health Center, Farmington 06030, USA
    J Neurochem 68:457-68. 1997
    ..The significance of DNA rearrangement in mammalian development is discussed...
  77. pmc A three-dimensional collagen lattice induces protein kinase C-zeta activity: role in alpha2 integrin and collagenase mRNA expression
    J Xu
    Department of Dermatology, School of Medicine, SUNY at Stony Brook, New York 11794-8165, USA
    J Cell Biol 136:473-83. 1997
    ..Thus, a three-dimensional collagen lattice maintains the dermal fibroblast phenotype, in part, through the activation of PKC-zeta...
  78. ncbi request reprint A novel pathway for tumor necrosis factor-alpha and ceramide signaling involving sequential activation of tyrosine kinase, p21(ras), and phosphatidylinositol 3-kinase
    A N Hanna
    Signal Transduction Laboratories, and the Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2S2, Canada
    J Biol Chem 274:12722-9. 1999
    ..It is proposed that activation of Ras and PI 3-kinase by ceramide can contribute to signaling effects of TNFalpha that occur downstream of sphingomyelinase activation and result in increased fibroblasts proliferation...
  79. ncbi request reprint Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding
    K Rittinger
    Divison of Protein Structure, National Institute for Medical Research, London, United Kingdom
    Mol Cell 4:153-66. 1999
    ..Structural homology between the 14-3-3 NES structure and those within I kappa B alpha and p53 reveals a conserved topology recognized by the Crm1 nuclear export machinery...
  80. ncbi request reprint Human sulfotransferases SULT1C1 and SULT1C2: cDNA characterization, gene cloning, and chromosomal localization
    R R Freimuth
    Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Medical School Mayo Graduate School Mayo Clinic, Rochester, Minnesota, 55905, USA
    Genomics 65:157-65. 2000
    ..2 by fluorescence in situ hybridization. The cloning and structural characterization of SULT1C1 and SULT1C2 will now make it possible to perform molecular genetic and pharmacogenomic studies of these sulfate-conjugating enzymes in humans...
  81. ncbi request reprint Transgenic studies in rats and mice on the osmotic regulation of vasopressin gene expression
    D Murphy
    Department of Medicine, Bristol Royal Infirmary, University of Bristol, UK
    Exp Physiol 85:211S-222S. 2000
    ....
  82. pmc Binding of ferric enterobactin by the Escherichia coli periplasmic protein FepB
    C Sprencel
    Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, USA
    J Bacteriol 182:5359-64. 2000
    ....
  83. ncbi request reprint [Cloning of cNDAs involved in malignant transformation induced by glycidyl methacrylate]
    J Xu
    Institute of Occupational Medicine, Chinese Academy of Preventive Medicine, Beijing 100050, China
    Wei Sheng Yan Jiu 30:14-7. 2001
    ..These results suggest that activation or inactivation of genes including ZABC1, Tbx3 and E2 may be involved in GMA-induced transformation...
  84. ncbi request reprint [Effect of methionine supplementation on the selenium bioavailability in rats fed on grains from Keshan disease endemic area]
    Y Tian
    Institute of Nutrition and Food Hygiene, Chinese Academy of Preventive Medicine, Beijing 100050, China
    Wei Sheng Yan Jiu 30:55-7. 2001
    ..The results further suggest that marginal deficiency in sulfur-containing amino acids in the diet from Keshan Disease endemic area might be an additional factor for the development of Keshan Disease under selenium deficiency...
  85. ncbi request reprint Epstein-Barr Virus and its glycoprotein-350 upregulate IL-6 in human B-lymphocytes via CD21, involving activation of NF-kappaB and different signaling pathways
    T A Libermann
    Laboratory of Immunovirology, Department of Microbiology and Immunology and Pediatric Research Center, University of Montreal, and Ste. Justine Hospital, , Montreal, Quebec H3T 1C5, Canada
    J Mol Biol 308:501-14. 2001
    ....
  86. ncbi request reprint [Expression of human anti-HBsAg-interferon fusion protein in CHO cells]
    Y Tong
    Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Gan Zang Bing Za Zhi 9:114-6. 2001
    ..CONCLUSIONS: The successful expression of a fusion protein with both HBsAg affinity and interferon activity may lead to a new way to make a targeting drug for hepatitis B...
  87. ncbi request reprint Cellular localization of tumor necrosis factor-alpha following acute spinal cord injury in adult rats
    P Yan
    Department of Anatomy and Neurobiology, Saint Louis University School of Medicine, Missouri 63104, USA
    J Neurotrauma 18:563-8. 2001
    ..Results suggest that various cell types, including neurons, glial cells, and vascular endothelial cells, contribute to TNF-alpha production in the injured cord...
  88. ncbi request reprint A kainate receptor increases the efficacy of GABAergic synapses
    L Jiang
    Department of Cell Biology and Anatomy, New York Medical College, Basic Science Building, Room 220, Valhalla, NY 10595, USA
    Neuron 30:503-13. 2001
    ..The results suggest that glutamate released from excitatory synapses may also function as an intermediary between excitatory and inhibitory synapses to protect overexcitation of local circuits...
  89. ncbi request reprint Tumor necrosis factor receptor deletion reduces nuclear factor-kappaB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury
    G M Kim
    Departments of Neurology and Center for the Study of Nervous System Injury, and Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 21:6617-25. 2001
    ..A worse functional outcome in TNFR(-/-) mice suggests that an endogenous apoptosis inhibitory mechanism mediated by TNFR activation, NF-kappaB, and c-IAP2 may be of pathophysiological importance...
  90. ncbi request reprint Suppression of tumorigenicity in human ovarian carcinoma cell line SKOV-3 by microcell-mediated transfer of chromosome 11
    Q Cao
    Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, NY, USA
    Cancer Genet Cytogenet 129:131-7. 2001
    ..Our results demonstrate functionally that chromosome 11 may carry a tumor suppressor gene(s) while chromosome 17 may carry a tumor growth-inhibitor gene(s) for the ovarian carcinoma cell line, SKOV-3...
  91. ncbi request reprint Reduction and restoration of mitochondrial dna content after focal cerebral ischemia/reperfusion
    H Chen
    Center for the Study of Nervous System Injury and Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Stroke 32:2382-7. 2001
    ..Restoration of the mtDNA content to nonischemic levels after 30-minute ischemia raises the possibility that mtDNA repair or repletion occurs after brief ischemia...
  92. ncbi request reprint Effects of glutathione on chromium-induced DNA crosslinking and DNA polymerase arrest
    J Xu
    Department of Pharmacology, The George Washington University Medical Center, Washington, DC 20037, USA
    Mol Cell Biochem 222:173-82. 2001
    ..Moreover, the formation of DNA-Cr-GSH crosslinks may actually preclude the formation of the polymerase arresting lesions...
  93. pmc Generation of the mu opioid receptor (MOR-1) protein by three new splice variants of the Oprm gene
    Y X Pan
    Laboratory of Molecular Neuropharmacology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 98:14084-9. 2001
    ..Although the truncated proteins are expressed in brain with a unique regional distribution, their functional significance remains unknown...
  94. ncbi request reprint [Primary respiratory syncytial virus infection in mice]
    Y Zou
    Guangzhou Institute of Respiratory Disease, Guangzhou 510120, China
    Zhonghua Jie He He Hu Xi Za Zhi 24:484-6. 2001
    ..CONCLUSION: An animal model of RSV infection Balb/c mice was successfully established by nasal inoculation with respiratory syncytial virus...
  95. ncbi request reprint Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
    F F Safadi
    Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA
    J Cell Biochem 84:12-26. 2001
    ..Furthermore, osteoactivin overexpression in op mutant bone may be secondary to the uncoupling of bone resorption and formation resulting in abnormalities in osteoblast gene expression and function...
  96. ncbi request reprint [Effect of platelet on procoagulant activity of monocyte]
    J Xu
    Hemostatic Physiology Laboratory, Xiangya Medical College, Central Southern University, Changsha 410078, China
    Zhonghua Xue Ye Xue Za Zhi 22:478-80. 2001
    ..CONCLUSION: TF expression of M contributes to the procoagulant activity of Ms and activated platelet enhances the procoagulant activity via P-selectin...
  97. ncbi request reprint Molecular genotyping of human cryptosporidiosis in Northern Ireland: epidemiological aspects and review
    C J Lowery
    Department of Bacteriology, Belfast City Hospital, School of Biological and Environmental Sciences, Faculty of Life and Health Sciences, University of Ulster, Coleraine, Northern Ireland
    Ir J Med Sci 170:246-50. 2001
    ..Epidemiologically, this suggests that the most frequent mode of transmission may be from animals to humans, but does not suggest a high proportion of human to human spread...
  98. ncbi request reprint [Identification of high-pathogenicity island-harboring Escherichia coli from children with diarrhea disease]
    L Li
    Molecular Microbiology Laboratory, Shanxi Children's Hospital, Taiyuan 030013, China
    Zhonghua Yi Xue Za Zhi 81:1427-9. 2001
    ..0%), diarrhea (75.9%, over 6 episodes, mostly of mucous stool a day, 75.9%), and fever (50.9%). CONCLUSION: High-pathogenicity island-harboring E. coli is one of the important pathogens of diarrhea diseases in children...
  99. ncbi request reprint Mycobacterium triplex pulmonary infection in an immunocompetent patient
    R McMullan
    Northern Ireland Public Health Laboratory, Belfast City Hospital, Lisburn Road, Belfast, Northern Ireland
    J Infect 44:263-4. 2002
    ..This novel organism is an uncommon, emerging, pathogen for which few reports of clinical infection exist in the medical literature...
  100. ncbi request reprint Human brain plasticity: an emerging view of the multiple substrates and mechanisms that cause cortical changes and related sensory dysfunctions after injuries of sensory inputs from the body
    J T Wall
    Cellular and Molecular Neurobiology Program, Medical College of Ohio, Toledo 43614 5804, USA
    Brain Res Brain Res Rev 39:181-215. 2002
    ..We suggest that sensory dysfunctions after nerve, root, dorsal column (spinal), and amputation injuries can be viewed as diseases of reorganization in this core...
  101. ncbi request reprint Employment of broad-range 16S rRNA PCR to detect aetiological agents of infection from clinical specimens in patients with acute meningitis--rapid separation of 16S rRNA PCR amplicons without the need for cloning
    J Xu
    Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Belfast, UK
    J Appl Microbiol 94:197-206. 2003
    ..The aim of this study was to develop a polyacrylamide gel electrophoresis (PAGE) method for the rapid separation of 16S rRNA PCR amplicons from aetiological agents of acute meningitis...