Zuo Liang Xiao

Summary

Publications

  1. ncbi request reprint Role of caveolae in the pathogenesis of cholesterol-induced gallbladder muscle hypomotility
    Zuoliang Xiao
    Division of Gastroenterology, APC 406, Rhode Island Hospital Brown Univ Medical School, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 292:G1641-9. 2007
  2. ncbi request reprint Nongenomic effects of progesterone on the contraction of muscle cells from the guinea pig colon
    Zuo Liang Xiao
    Division of Gastroenterology, APC 406, Rhode Island Hospital Brown University Medical School, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 290:G1008-15. 2006
  3. ncbi request reprint Role of PGE2 on gallbladder muscle cytoprotection of guinea pigs
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Am J Physiol Gastrointest Liver Physiol 286:G82-8. 2004
  4. ncbi request reprint Hydrophilic but not hydrophobic bile acids prevent gallbladder muscle dysfunction in acute cholecystitis
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, RI, USA
    Hepatology 37:1442-50. 2003
  5. ncbi request reprint Impaired cytoprotective function of muscle in human gallbladders with cholesterol stones
    Zuo Liang Xiao
    Division of Gastroenterology, APC 421, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 288:G525-32. 2005
  6. ncbi request reprint PAF-like lipids- and PAF-induced gallbladder muscle contraction is mediated by different pathways in guinea pigs
    Michele P L Guarino
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Am J Physiol Gastrointest Liver Physiol 285:G1189-97. 2003
  7. ncbi request reprint Prostaglandins mediate tonic contraction of the guinea pig and human gallbladder
    Ping Cong
    Division of Gastroenterology, Department of Medicine, Rhode Island Hospital Brown Univ Medical School, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 292:G409-18. 2007
  8. ncbi request reprint Effects of bile acids on the muscle functions of guinea pig gallbladder
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Am J Physiol Gastrointest Liver Physiol 283:G87-94. 2002
  9. ncbi request reprint Role of progesterone signaling in the regulation of G-protein levels in female chronic constipation
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Gastroenterology 128:667-75. 2005
  10. ncbi request reprint Reactive oxygen species (H(2)O(2)): effects on the gallbladder muscle of guinea pigs
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, 593 Eddy Street, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 282:G300-6. 2002

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Role of caveolae in the pathogenesis of cholesterol-induced gallbladder muscle hypomotility
    Zuoliang Xiao
    Division of Gastroenterology, APC 406, Rhode Island Hospital Brown Univ Medical School, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 292:G1641-9. 2007
    ....
  2. ncbi request reprint Nongenomic effects of progesterone on the contraction of muscle cells from the guinea pig colon
    Zuo Liang Xiao
    Division of Gastroenterology, APC 406, Rhode Island Hospital Brown University Medical School, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 290:G1008-15. 2006
    ..This effect does not appear to be specific to PG because other steroid hormones such as aldosterone and testosterone can also induce it...
  3. ncbi request reprint Role of PGE2 on gallbladder muscle cytoprotection of guinea pigs
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Am J Physiol Gastrointest Liver Physiol 286:G82-8. 2004
    ..The preservation of PGE2 receptors may be designed to conserve these cytoprotective functions that are, however, impaired by the presence of excess cholesterol in the plasma membrane...
  4. ncbi request reprint Hydrophilic but not hydrophobic bile acids prevent gallbladder muscle dysfunction in acute cholecystitis
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, RI, USA
    Hepatology 37:1442-50. 2003
    ..In conclusion, oral treatment with UDCA prevents gallbladder muscle damage caused by BDL, whereas oral treatment with CDCA worsens the defective muscle contractility and the oxidative stress...
  5. ncbi request reprint Impaired cytoprotective function of muscle in human gallbladders with cholesterol stones
    Zuo Liang Xiao
    Division of Gastroenterology, APC 421, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 288:G525-32. 2005
    ..This impaired cytoprotective response may be due to a dysfunction of PGE(2) receptors with decreased binding capacity resulting from excessive Ch levels in the plasma membrane...
  6. ncbi request reprint PAF-like lipids- and PAF-induced gallbladder muscle contraction is mediated by different pathways in guinea pigs
    Michele P L Guarino
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Am J Physiol Gastrointest Liver Physiol 285:G1189-97. 2003
    ..In conclusion, PAF-like lipids seem to activate a pathway different from that of PAF probably by stimulating a different PAF receptor subtype...
  7. ncbi request reprint Prostaglandins mediate tonic contraction of the guinea pig and human gallbladder
    Ping Cong
    Division of Gastroenterology, Department of Medicine, Rhode Island Hospital Brown Univ Medical School, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 292:G409-18. 2007
    ..We conclude that PGE2 generated by COX-2 and TxA2 generated by COX-1 contributes to the maintenance of GB tonic contraction and that variations in tonic contraction are associated with concomitant changes in PGE2 and TxA2 levels...
  8. ncbi request reprint Effects of bile acids on the muscle functions of guinea pig gallbladder
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Am J Physiol Gastrointest Liver Physiol 283:G87-94. 2002
    ..H2O2 causes lipid peroxidation and activates cPLA2 to increase PGE2 production, which, in turn, stimulates the synthesis of free-radical scavengers through the PKC-MAPK pathway...
  9. ncbi request reprint Role of progesterone signaling in the regulation of G-protein levels in female chronic constipation
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, Providence, Rhode Island 02903, USA
    Gastroenterology 128:667-75. 2005
    ..The cause and mechanisms responsible for this syndrome are unknown. Progesterone has been suggested as a possible contributing factor. Our aim was to investigate the site and mechanisms responsible for this colonic motility disorder...
  10. ncbi request reprint Reactive oxygen species (H(2)O(2)): effects on the gallbladder muscle of guinea pigs
    Zuo Liang Xiao
    Department of Medicine, Rhode Island Hospital and Brown University School of Medicine, 593 Eddy Street, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 282:G300-6. 2002
    ..It is concluded that ROS cause damage to the plasma membrane of the gallbladder muscle and contraction through the generation of PGE(2) induced by cPLA(2)-cyclooxygenase and probably mediated by the PKC-MAPK pathway...
  11. ncbi request reprint Reactive oxygen species are messengers in maintenance of human and guinea pig gallbladder tonic contraction
    Ping Cong
    Division of Gastroenterology, APC 406, Rhode Island Hospital Brown Univ Medical School, 593 Eddy St, Providence, RI 02903, USA
    Am J Physiol Gastrointest Liver Physiol 293:G1244-51. 2007
    ..H(2)O(2) generated by NADPH oxidase participates in a signal transduction pathway that maintains the GB tonic contraction by activating PAF, p38, and cPLA(2) to generate prostaglandins...