Philipp S Wild

Summary

Publications

  1. doi request reprint Distribution and categorization of left ventricular measurements in the general population: results from the population-based Gutenberg Heart Study
    Philipp S Wild
    Department of Medicine II, Institute for Clinical Chemistry, Johannes Gutenberg University Mainz, Mainz, Germany
    Circ Cardiovasc Imaging 3:604-13. 2010
  2. pmc Psychodynamic Motivation and Training program (PMT) for the secondary prevention in patients with stable coronary heart disease: study protocol for a randomized controlled trial of feasibility and effects
    Matthias Michal
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Untere Zahlbacher Strasse 8, Mainz 55131, Germany
    Trials 14:314. 2013
  3. pmc The Gutenberg Health Study: measuring psychosocial factors at work and predicting health and work-related outcomes with the ERI and the COPSOQ questionnaire
    Matthias Nuebling
    FFAS, Freiburg Research Center for Occupational and Social Medicine, Bertoldstr, 27, D 79098 Freiburg, Germany
    BMC Public Health 13:538. 2013
  4. doi request reprint [The Gutenberg Health Study]
    P S Wild
    Centrum für Thrombose und Hämostase, Universitätsmedizin Mainz, Johannes Gutenberg Universitat Mainz, Langenbeckstr 1, 55131, Mainz, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:824-9. 2012
  5. doi request reprint Defining a reference population to determine the 99th percentile of a contemporary sensitive cardiac troponin I assay
    Till Keller
    Department of Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany
    Int J Cardiol 167:1423-9. 2013
  6. pmc Differential associations of depressive symptom dimensions with cardio-vascular disease in the community: results from the Gutenberg health study
    Matthias Michal
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
    PLoS ONE 8:e72014. 2013
  7. doi request reprint MR-proANP and MR-proADM for risk stratification of patients with acute chest pain
    Stergios Tzikas
    Department of Medicine 2, University Medical Center Mainz, Mainz, Germany
    Heart 99:388-95. 2013
  8. doi request reprint Prognostic information of glycogen phosphorylase isoenzyme BB in patients with suspected acute coronary syndrome
    Lars Lillpopp
    Department of Internal Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany
    Am J Cardiol 110:1225-30. 2012
  9. doi request reprint Midregional proadrenomedullin for prediction of cardiovascular events in coronary artery disease: results from the AtheroGene study
    Philipp S Wild
    Department of Medicine II, University Medical Center Mainz, Johannes Gutenberg University Mainz, Germany
    Clin Chem 58:226-36. 2012
  10. doi request reprint Copeptin improves early diagnosis of acute myocardial infarction
    Till Keller
    Department of Medicine II, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
    J Am Coll Cardiol 55:2096-106. 2010

Detail Information

Publications39

  1. doi request reprint Distribution and categorization of left ventricular measurements in the general population: results from the population-based Gutenberg Heart Study
    Philipp S Wild
    Department of Medicine II, Institute for Clinical Chemistry, Johannes Gutenberg University Mainz, Mainz, Germany
    Circ Cardiovasc Imaging 3:604-13. 2010
    ..This work presents empirically derived reference values from a large-scale, epidemiologic study conducted with state-of-the-art imaging technology and methods...
  2. pmc Psychodynamic Motivation and Training program (PMT) for the secondary prevention in patients with stable coronary heart disease: study protocol for a randomized controlled trial of feasibility and effects
    Matthias Michal
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Untere Zahlbacher Strasse 8, Mainz 55131, Germany
    Trials 14:314. 2013
    ..Psychotherapeutic approaches that address how persons think about themselves and their behaviors appear to have a significant potential for improving health behavior...
  3. pmc The Gutenberg Health Study: measuring psychosocial factors at work and predicting health and work-related outcomes with the ERI and the COPSOQ questionnaire
    Matthias Nuebling
    FFAS, Freiburg Research Center for Occupational and Social Medicine, Bertoldstr, 27, D 79098 Freiburg, Germany
    BMC Public Health 13:538. 2013
    ..We compared two of these instruments, the Effort-Reward Imbalance (ERI) model and the Copenhagen Psychosocial Questionnaire (COPSOQ) with regard to congruent validity and internal validity...
  4. doi request reprint [The Gutenberg Health Study]
    P S Wild
    Centrum für Thrombose und Hämostase, Universitätsmedizin Mainz, Johannes Gutenberg Universitat Mainz, Langenbeckstr 1, 55131, Mainz, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 55:824-9. 2012
    ..5 years. After 5 years a detailed follow-up examination comparable to the visit at study inclusion will be performed in the study center. Further follow-up visits of the cohort are envisaged...
  5. doi request reprint Defining a reference population to determine the 99th percentile of a contemporary sensitive cardiac troponin I assay
    Till Keller
    Department of Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany
    Int J Cardiol 167:1423-9. 2013
    ..Aim of the current study was to describe the distribution of troponin I using a sensitive assay and to evaluate the impact of cardiac diseases and cardiovascular risk factors in apparently healthy individuals...
  6. pmc Differential associations of depressive symptom dimensions with cardio-vascular disease in the community: results from the Gutenberg health study
    Matthias Michal
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
    PLoS ONE 8:e72014. 2013
    ..They rather emphasize a close interplay with life-style factors and with a family history of MI. ..
  7. doi request reprint MR-proANP and MR-proADM for risk stratification of patients with acute chest pain
    Stergios Tzikas
    Department of Medicine 2, University Medical Center Mainz, Mainz, Germany
    Heart 99:388-95. 2013
    ..To evaluate mid-regional pro-adrenomedullin (MR-proADM) and mid-regional pro-atrial natriuretic peptide (MR-proANP) as prognostic biomarkers in a representative 'real world' cohort of patients with suspected acute coronary syndrome (ACS)...
  8. doi request reprint Prognostic information of glycogen phosphorylase isoenzyme BB in patients with suspected acute coronary syndrome
    Lars Lillpopp
    Department of Internal Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany
    Am J Cardiol 110:1225-30. 2012
    ..In conclusion, GPBB measurement provides predictive information on midterm prognosis in patients with chest pain in addition to BNP and troponin I...
  9. doi request reprint Midregional proadrenomedullin for prediction of cardiovascular events in coronary artery disease: results from the AtheroGene study
    Philipp S Wild
    Department of Medicine II, University Medical Center Mainz, Johannes Gutenberg University Mainz, Germany
    Clin Chem 58:226-36. 2012
    ..We evaluated the prognostic impact of MR-proADM in a cohort of patients with symptomatic coronary artery disease according to their clinical presentation...
  10. doi request reprint Copeptin improves early diagnosis of acute myocardial infarction
    Till Keller
    Department of Medicine II, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
    J Am Coll Cardiol 55:2096-106. 2010
    ..Early identification of myocardial infarction in chest pain patients is crucial to identify patients at risk and to maintain a fast treatment initiation...
  11. doi request reprint Correlations between central corneal thickness and general anthropometric characteristics and cardiovascular parameters in a large European cohort from the Gutenberg Health Study
    Heike M Elflein
    Department of Ophthalmology, University Medical Center Mainz, Johannes Gutenberg University Mainz, Germany Institute of Medical Biostatistics, Epidemiology and Informatics IMBEI, University Medical Center Mainz, Johannes Gutenberg University Mainz, Germany and Department of Medicine II, University Medical Center Mainz, Johannes Gutenberg University Mainz, Germany
    Cornea 33:359-65. 2014
    ..The aim of this study was to evaluate the correlations between general anthropometric features and cardiovascular parameters and central corneal thickness (CCT) in an adult European cohort...
  12. pmc Associations between depression and different measures of obesity (BMI, WC, WHtR, WHR)
    Jorg Wiltink
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
    BMC Psychiatry 13:223. 2013
    ..Our aim was therefore to relate body mass index (BMI) and different measures for abdominal obesity (waist circumference, WC, waist-to-hip ratio, WHR, waist-to-height ratio, WHtR) to somatic vs. cognitive-affective symptoms of depression...
  13. ncbi request reprint Association of serum procalcitonin with cardiovascular prognosis in coronary artery disease
    Christoph R Sinning
    Department of Medicine II, University Medical Centre Johannes Gutenberg University, Mainz, Germany
    Circ J 75:1184-91. 2011
    ..Procalcitonin (PCT) is an established biomarker for the diagnosis of sepsis. Evidence is growing that PCT concentration correlates with the extent of atherosclerosis and prognosis in patients with coronary artery disease (CAD)...
  14. pmc Serum selenium and prognosis in cardiovascular disease: results from the AtheroGene study
    Edith Lubos
    Department of Medicine II, Johannes Gutenberg University Mainz, Langenbeckstr 1, Mainz, Germany
    Atherosclerosis 209:271-7. 2010
    ..We aimed to investigate the impact of serum selenium concentration in patients presenting with stable angina pectoris (SAP) or acute coronary syndrome (ACS) on long term prognosis...
  15. doi request reprint Multiple marker approach to risk stratification in patients with stable coronary artery disease
    Renate B Schnabel
    Department of Medicine II, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr 1, 55131 Mainz, Germany
    Eur Heart J 31:3024-31. 2010
    ..multimarker approaches for risk prediction in coronary artery disease have remained inconsistent. We assessed multiple biomarkers representing distinct pathophysiological pathways in relation to cardiovascular events in stable angina...
  16. doi request reprint History of deep vein thrombosis is a discriminator for concomitant atrial fibrillation in pulmonary embolism
    Karsten Keller
    Center for Thrombosis and Hemostasis, Mainz, University Medical Center Mainz of Johannes Gutenberg University Mainz, Germany Department of Medicine 2, University Medical Center Mainz of Johannes Gutenberg University Mainz, Mainz, Germany
    Thromb Res 136:899-906. 2015
    ..Although, PE and DVT are commonly related to risk factors of Virchow's triad, both entities are linked to cardiovascular risk factors, but risk factors seem differently important in both entities...
  17. doi request reprint Symptoms of depression and anxiety predict mortality in patients undergoing oral anticoagulation: Results from the thrombEVAL study program
    Matthias Michal
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany DZHK German Center for Cardiovascular Research, partner site Rhine Main, Mainz, Germany Electronic address
    Int J Cardiol 187:614-9. 2015
    ..Therefore, we examined whether the 4-item Patient Health Questionnaire (PHQ-4, measuring symptoms of depression and anxiety) predicts all-cause mortality in outpatients with long-term oral anticoagulation (OAC)...
  18. pmc Complaints of sleep disturbances are associated with cardiovascular disease: results from the Gutenberg Health Study
    Matthias Michal
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, Mainz, Germany German Center for Cardiovascular Research DZHK, partner site Rhine Main, Germany
    PLoS ONE 9:e104324. 2014
    ....
  19. pmc Distribution of central corneal thickness and its association with ocular parameters in a large central European cohort: the Gutenberg health study
    Esther M Hoffmann
    University Medical Centre, Department of Ophthalmology, Mainz, Germany
    PLoS ONE 8:e66158. 2013
    ..To evaluate the distribution of central corneal thickness (CCT) in a large German cohort and to analyse its relationship with intraocular pressure and further ocular factors...
  20. doi request reprint Noninvasive vascular function measurement in the community: cross-sectional relations and comparison of methods
    Renate B Schnabel
    Department of Medicine 2, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
    Circ Cardiovasc Imaging 4:371-80. 2011
    ..A direct comparison of the different methods and their relation to classical cardiovascular risk factors in a large cohort is missing...
  21. doi request reprint Prevalence of age-related macular degeneration in a large European cohort: results from the population-based Gutenberg Health Study
    Christina A Korb
    Department of Ophthalmology, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstr 1, 55131, Mainz, Germany
    Graefes Arch Clin Exp Ophthalmol 252:1403-11. 2014
    ..The aim of this study was to describe the sex- and age-specific prevalence of age-related macular degeneration (AMD) and its correlation with urban or rural residence in a large and relatively young European cohort...
  22. doi request reprint Sex differences in noninvasive vascular function in the community
    Renate B Schnabel
    Department of General and Interventional Cardiology, University Heart Center, Hamburg Eppendorf, Hamburg, Germany
    J Hypertens 31:1437-46; discussion 1446. 2013
    ..The relation of noninvasive vascular function to sex, sex hormones, and reproductive history in the general population is little understood...
  23. doi request reprint The distribution of whole blood viscosity, its determinants and relationship with arterial blood pressure in the community: cross-sectional analysis from the Gutenberg Health Study
    Tommaso Gori
    Medizinische Klinik und Poliklinik, University Medical Center of the Johannes Gutenberg University Mainz, Langenbeckstr 1, 55131 Mainz, Germany
    Ther Adv Cardiovasc Dis 9:354-65. 2015
    ..We report data on the normal values of blood viscosity and its association with cardiovascular risk factors, prevalent cardiovascular disease, and blood pressure in a large population-based cohort study...
  24. pmc Prevalence and Cardiovascular Associations of Diabetic Retinopathy and Maculopathy: Results from the Gutenberg Health Study
    Philipp Raum
    Department of Ophthalmology, University Medical Center, Mainz, Germany
    PLoS ONE 10:e0127188. 2015
    ..Diabetic retinopathy (DR) is the leading cause of blindness in people of working age. The purpose of this paper is to report the prevalence and cardiovascular associations of diabetic retinopathy and maculopathy (DMac) in Germany...
  25. pmc Associations between depression and diabetes in the community: do symptom dimensions matter? Results from the Gutenberg Health Study
    Jorg Wiltink
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany
    PLoS ONE 9:e105499. 2014
    ..While a bidirectional relationship between diabetes and depression has been established, there is little knowledge if the associations are due to somatic-affective or cognitive-affective dimensions of depression...
  26. doi request reprint Cystatin C and cardiovascular mortality in patients with coronary artery disease and normal or mildly reduced kidney function: results from the AtheroGene study
    Till Keller
    Department of Medicine II, Johannes Gutenberg University Mainz, Langenbeckstr 1, 55131 Mainz, Germany
    Eur Heart J 30:314-20. 2009
    ..Cystatin C is a promising marker to reliably mirror renal function. The role of cystatin C in patients with coronary artery disease (CAD) and normal or mildly reduced kidney function is the subject of current investigation...
  27. pmc Rationale and design of three observational, prospective cohort studies including biobanking to evaluate and improve diagnostics, management strategies and risk stratification in venous thromboembolism: the VTEval Project
    Bernd Frank
    Center for Thrombosis and Hemostasis CTH, University Medical Center Mainz, Mainz, Germany
    BMJ Open 5:e008157. 2015
    ..The VTEval Project aims to investigate numerous research questions on diagnosis, clinical management, treatment and prognosis of VTE, which have remained uncertain to date...
  28. doi request reprint Distribution of intraocular pressure and its association with ocular features and cardiovascular risk factors: the Gutenberg Health Study
    Rene Hoehn
    Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany
    Ophthalmology 120:961-8. 2013
    ..To describe the distribution of intraocular pressure (IOP) and its association with ocular features and cardiovascular risk factors in an adult European cohort...
  29. doi request reprint Contribution of 30 biomarkers to 10-year cardiovascular risk estimation in 2 population cohorts: the MONICA, risk, genetics, archiving, and monograph (MORGAM) biomarker project
    Stefan Blankenberg
    Department of Medicine II, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany
    Circulation 121:2388-97. 2010
    ..We report results from 2 cohorts in such a continuing study...
  30. pmc A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease
    Philipp S Wild
    Department of Medicine II, University Medical Center Mainz, Germany
    Circ Cardiovasc Genet 4:403-12. 2011
    ..We performed a genome-wide association and global gene expression study to identify functionally relevant variants affecting the risk of coronary artery disease (CAD)...
  31. pmc Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study
    Renate Schnabel
    Department of Medicine II, Johannes Gutenberg University, Mainz, Germany
    Am Heart J 156:1201.e1-11. 2008
    ..We assessed the effect of selenium supplementation on GPx-1 in cell culture and on endothelial function in a prospective clinical trial...
  32. doi request reprint Prevalence of distress, comorbid conditions and well being in the general population
    Jorg Wiltink
    Clinic of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Germany
    J Affect Disord 130:429-37. 2011
    ..The purposes of this paper are to determine the prevalence of distress in the community, to identify its determinants and to assess its relationship to somatic conditions and subjective well being...
  33. doi request reprint Profile of the Immune and Inflammatory Response in Individuals With Prediabetes and Type 2 Diabetes
    Vera Grossmann
    Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany
    Diabetes Care 38:1356-64. 2015
    ..The inflammatory and immune systems are altered in type 2 diabetes. Here, the aim was to profile the immune and inflammatory response in subjects with prediabetes and diabetes in a large population-representative sample...
  34. pmc Quality of oral anticoagulation with phenprocoumon in regular medical care and its potential for improvement in a telemedicine-based coagulation service--results from the prospective, multi-center, observational cohort study thrombEVAL
    Jürgen H Prochaska
    Center for Thrombosis and Hemostasis, University Medical Center Mainz, Johannes Gutenberg University Mainz, Langenbeckstr 1, 55131, Mainz, Germany
    BMC Med 13:14. 2015
    ..In this study, we aimed to assess quality of OAC therapy with phenprocoumon in regular medical care and to evaluate its potential for optimization in a telemedicine-based coagulation service...
  35. doi request reprint Predictive value of brachial reactive hyperemia and flow-mediated dilation in stable coronary artery disease
    Mir Abolfazl Ostad
    Department of Medicine II, University Medical Center Mainz, Germany
    Clin Hemorheol Microcirc 56:247-57. 2014
    ..The purpose of this study was to determine the predictive value of a single measurement of reactive hyperemia (RH) and brachial flow-mediated dilation (FMD) in patients with established stable coronary artery disease (CAD)...
  36. doi request reprint Association of hypertension with depression in the community: results from the Gutenberg Health Study
    Matthias Michal
    Department of Psychosomatic Medicine and Psychotherapy, Mainz, Germany
    J Hypertens 31:893-9. 2013
    ..Previous studies reported close positive as well as close negative associations between HTN and depression. Against this background, the present study sought to analyze this relationship in a large population-based study...
  37. doi request reprint Sensitive troponin I assay in early diagnosis of acute myocardial infarction
    Till Keller
    Department of Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany
    N Engl J Med 361:868-77. 2009
    ..Cardiac troponin testing is central to the diagnosis of acute myocardial infarction. We evaluated a sensitive troponin I assay for the early diagnosis and risk stratification of myocardial infarction...
  38. doi request reprint Fragment reconstruction of coronary arteries using transesophageal echocardiography for coronary diagnostics
    Philipp S Wild
    Department of Medicine II, Johannes Gutenberg University Mainz, Langenbeckstr 27, 55101 Mainz, Germany
    Eur J Echocardiogr 9:796-802. 2008
    ..In this study, fragment reconstruction of coronary arteries by transesophageal echocardiography (FRC-TEE) was investigated for the first time in a patient population being evaluated for coronary angiography...
  39. doi request reprint Evaluation of oral anticoagulation therapy: rationale and design of the thrombEVAL study programme
    Jürgen H Prochaska
    Centre for Thrombosis and Haemostasis, University Medical Centre Mainz, Johannes Gutenberg University Mainz, Germany Department of Medicine 2, University Medical Centre Mainz, Johannes Gutenberg University Mainz, Germany
    Eur J Prev Cardiol 22:622-8. 2015
    ..However, data on quality and management of VKA therapy with phenprocoumon in current medical care are limited. Our aim is to investigate the quality of OAC with VKA in current health care and to evaluate the potential for improvements...