Paul Wicks

Summary

Publications

  1. doi Pathological gambling amongst Parkinson's disease and ALS patients in an online community (PatientsLikeMe.com)
    Paul Wicks
    Research and Development, PatientsLikeMe Inc, Cambridge, Massachusetts, USA
    Mov Disord 24:1085-8. 2009
  2. pmc It's a long shot, but it just might work! Perspectives on the future of medicine
    Paul Wicks
    PatientsLikeMe, 10 John Street, London, WC1N 2EB, UK
    BMC Med 14:176. 2016
  3. pmc The real-world patient experience of fingolimod and dimethyl fumarate for multiple sclerosis
    Paul Wicks
    PatientsLikeMe, 160 Second Street, Cambridge, MA, 02142, USA
    BMC Res Notes 9:434. 2016
  4. pmc Preferred features of oral treatments and predictors of non-adherence: two web-based choice experiments in multiple sclerosis patients
    Paul Wicks
    PatientsLikeMe, Cambridge, MA, United States
    Interact J Med Res 4:e6. 2015
  5. pmc 'Trust but verify'--five approaches to ensure safe medical apps
    Paul Wicks
    155 2nd Street, PatientsLikeMe, Cambridge, MA, 02141, USA
    BMC Med 13:205. 2015
  6. pmc Adaptation and validation of the Treatment Burden Questionnaire (TBQ) in English using an internet platform
    Viet Thi Tran
    Department of General Medicine, Paris Diderot University, Paris, France
    BMC Med 12:109. 2014
  7. pmc Could digital patient communities be the launch pad for patient-centric trial design?
    Paul Wicks
    PatientsLikeMe, 155 2nd Street, Cambridge, MA 02141, USA
    Trials 15:172. 2014
  8. pmc Quality of life in organ transplant recipients participating in an online transplant community
    Paul Wicks
    PatientsLikeMe, Inc, 155 Second St, Cambridge, MA, 02141, USA
    Patient 7:73-84. 2014
  9. pmc The multiple sclerosis rating scale, revised (MSRS-R): development, refinement, and psychometric validation using an online community
    Paul Wicks
    PatientsLikeMe Inc, 155 Second Street, Cambridge, MA 02141, USA
    Health Qual Life Outcomes 10:70. 2012
  10. pmc Hypothesis: higher prenatal testosterone predisposes ALS patients to improved athletic performance and manual professions
    Paul Wicks
    PatientsLikeMe, Research and Development, Cambridge, Massachusetts 02141, USA
    Amyotroph Lateral Scler 13:251-3. 2012

Collaborators

Detail Information

Publications25

  1. doi Pathological gambling amongst Parkinson's disease and ALS patients in an online community (PatientsLikeMe.com)
    Paul Wicks
    Research and Development, PatientsLikeMe Inc, Cambridge, Massachusetts, USA
    Mov Disord 24:1085-8. 2009
    ..Thus, the higher prevalence of compulsive behavior in PD may relate to damaged reward pathways or medication rather than to the effects of living with a chronic progressive neurological disorder per se...
  2. pmc It's a long shot, but it just might work! Perspectives on the future of medicine
    Paul Wicks
    PatientsLikeMe, 10 John Street, London, WC1N 2EB, UK
    BMC Med 14:176. 2016
    ....
  3. pmc The real-world patient experience of fingolimod and dimethyl fumarate for multiple sclerosis
    Paul Wicks
    PatientsLikeMe, 160 Second Street, Cambridge, MA, 02142, USA
    BMC Res Notes 9:434. 2016
    ..Oral disease-modifying therapies offer equivalent or superior efficacy and greater convenience versus injectable options...
  4. pmc Preferred features of oral treatments and predictors of non-adherence: two web-based choice experiments in multiple sclerosis patients
    Paul Wicks
    PatientsLikeMe, Cambridge, MA, United States
    Interact J Med Res 4:e6. 2015
    ..Oral disease modifying therapies (DMTs) for multiple sclerosis (MS) differ in efficacy, tolerability, and safety...
  5. pmc 'Trust but verify'--five approaches to ensure safe medical apps
    Paul Wicks
    155 2nd Street, PatientsLikeMe, Cambridge, MA, 02141, USA
    BMC Med 13:205. 2015
    ..Please see related articles: http://dx.doi.org/10.1186/s12916-015-0444-y , http://www.biomedcentral.com/1741-7015/13/106 and http://www.biomedcentral.com/1741-7015/13/58...
  6. pmc Adaptation and validation of the Treatment Burden Questionnaire (TBQ) in English using an internet platform
    Viet Thi Tran
    Department of General Medicine, Paris Diderot University, Paris, France
    BMC Med 12:109. 2014
    ..Here, we aimed to evaluate the validity and reliability of an English version of the TBQ, a scale that was originally developed in French...
  7. pmc Could digital patient communities be the launch pad for patient-centric trial design?
    Paul Wicks
    PatientsLikeMe, 155 2nd Street, Cambridge, MA 02141, USA
    Trials 15:172. 2014
    ..The patient is only a subject. Is it any wonder, then, that some patients have rejected the current medical paradigm and sought to find their own path? ..
  8. pmc Quality of life in organ transplant recipients participating in an online transplant community
    Paul Wicks
    PatientsLikeMe, Inc, 155 Second St, Cambridge, MA, 02141, USA
    Patient 7:73-84. 2014
    ..The PatientsLikeMe Organ Transplants online community allows patients to share detailed health information for research...
  9. pmc The multiple sclerosis rating scale, revised (MSRS-R): development, refinement, and psychometric validation using an online community
    Paul Wicks
    PatientsLikeMe Inc, 155 Second Street, Cambridge, MA 02141, USA
    Health Qual Life Outcomes 10:70. 2012
    ..Existing measures of functional status were inadequate, clinician-reported, focused on walking, and burdensome to complete. In response, we developed the Multiple Sclerosis Rating Scale (MSRS)...
  10. pmc Hypothesis: higher prenatal testosterone predisposes ALS patients to improved athletic performance and manual professions
    Paul Wicks
    PatientsLikeMe, Research and Development, Cambridge, Massachusetts 02141, USA
    Amyotroph Lateral Scler 13:251-3. 2012
    ..This hypothesis may serve as a starting point for debate and discussion over the nature of ALS risk factors, as well as generating a number of specific testable hypotheses that may yield insight into the genesis of the disease...
  11. doi Perceived benefits of sharing health data between people with epilepsy on an online platform
    Paul Wicks
    PatientsLikeMe Inc, Cambridge, MA 02141, USA
    Epilepsy Behav 23:16-23. 2012
    ..Controlled sharing of health data may have the potential to improve disease self-management of people with epilepsy...
  12. doi Measuring function in advanced ALS: validation of ALSFRS-EX extension items
    P Wicks
    PatientsLikeMe Inc, Research and Development, Cambridge, MA 02142, USA
    Eur J Neurol 16:353-9. 2009
    ..There is a research need to monitor patient function at the end of life, particularly in the face of severe impairment or 'locked in syndrome'...
  13. pmc Sharing health data for better outcomes on PatientsLikeMe
    Paul Wicks
    PatientsLikeMe Inc, Research and Development, 155 2nd Street, Cambridge, MA 02141, USA
    J Med Internet Res 12:e19. 2010
    ..The goal of the website is to help patients answer the question: "Given my status, what is the best outcome I can hope to achieve, and how do I get there?"..
  14. pmc Use of an online community to develop patient-reported outcome instruments: the Multiple Sclerosis Treatment Adherence Questionnaire (MS-TAQ)
    Paul Wicks
    PatientsLikeMe, Research and Development, Cambridge, MA 02141, USA
    J Med Internet Res 13:e12. 2011
    ..Patients with multiple sclerosis (MS) may face barriers, such as treatment fatigue, memory problems, or side effects, that may influence their adherence to medication...
  15. doi Accelerated clinical discovery using self-reported patient data collected online and a patient-matching algorithm
    Paul Wicks
    Research and Development, PatientsLikeMe Inc, Cambridge, Massachusetts, USA
    Nat Biotechnol 29:411-4. 2011
    ....
  16. pmc Correction of: Exploring Concordance of Patient-Reported Information on PatientsLikeMe and Medical Claims Data at the Patient Level
    Gabriel S Eichler
    PatientsLikeMe, Cambridge, MA, United States
    J Med Internet Res 18:e271. 2016
    ..This corrects the article DOI: 10.2196/jmir.5130.]...
  17. pmc The potential research impact of patient reported outcomes on osteogenesis imperfecta
    Catherine A Brownstein
    PatientsLikeMe Research and Development, 155 2nd St, Cambridge, MA 02141, USA
    Clin Orthop Relat Res 468:2581-5. 2010
    ..Because treatment is not standardized and is often experimental, information on the success of different methods is usually not available or well documented...
  18. pmc Quantifying short-term dynamics of Parkinson's disease using self-reported symptom data from an Internet social network
    Max Little
    Human Dynamics Group, Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139, United States
    J Med Internet Res 15:e20. 2013
    ..Currently, there is a scarcity of objective clinical information about symptom dynamics at intervals shorter than 3 months stretching over several years, but Internet-based patient self-report platforms may change this...
  19. doi New approach for analyzing self-reporting of insomnia symptoms reveals a high rate of comorbid insomnia across a wide spectrum of chronic diseases
    Bozena Katic
    PatientsLikeMe Inc, Cambridge, MA, USA Electronic address
    Sleep Med 16:1332-41. 2015
    ..Insomnia is increasingly recognized to be comorbid with one or more medical conditions. This study used an online research platform to characterize insomnia across different mental and physical conditions...
  20. ncbi Three soccer playing friends with simultaneous amyotrophic lateral sclerosis
    Paul Wicks
    MRC Centre for Neurodegeneration Research, King s College London, Institute of Psychiatry, Department of Psychology, London, UK
    Amyotroph Lateral Scler 8:177-9. 2007
    ..We report a cluster of three amateur league soccer players who were friends from the same part of southern England, and developed ALS simultaneously. This might suggest that keen amateur soccer players are also at risk...
  21. pmc Exploring Concordance of Patient-Reported Information on PatientsLikeMe and Medical Claims Data at the Patient Level
    Gabriel S Eichler
    PatientsLikeMe, Cambridge, MA, United States
    J Med Internet Res 18:e110. 2016
    ..With the emergence of data generated by patient-powered research networks, it is informative to characterize their correspondence with health care system-generated data...
  22. doi Increasing Patient Involvement in Drug Development
    Maria M Lowe
    PatientsLikeMe, Cambridge, MA, USA Electronic address
    Value Health 19:869-878. 2016
    ..Despite growing efforts to engage patients in research and regulatory activities, the pharmaceutical industry has yet to maximize patient involvement in the drug development process...
  23. pmc How common are ALS plateaus and reversals?
    Richard S Bedlack
    From the Department of Neurology R S B, Duke University and Durham VA Medical Center, Durham, NC PatientsLikeMe T V, P W, J H, Cambridge, MA Massachusetts General Hospital E S, R S, E A M, D S, M C, A s, Boston and Harvard Medical School E A M, Boston, MA
    Neurology 86:808-12. 2016
    ..To determine the frequency of amyotrophic lateral sclerosis (ALS) plateaus and reversals in the Pooled Resource Open-Access ALS Clinical Trials (PRO-ACT) database...
  24. pmc Evaluation of an online platform for multiple sclerosis research: patient description, validation of severity scale, and exploration of BMI effects on disease course
    Riley Bove
    Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Institute for the Neurosciences, Brigham and Women s Hospital, Boston, Massachusetts, United States of America
    PLoS ONE 8:e59707. 2013
    ..com (PLM), for research in multiple sclerosis (MS). An investigation of the role of body mass index (BMI) on MS disease course was conducted to illustrate the utility of the platform...