Phurpa Wangchuk

Summary

Publications

  1. ncbi request reprint Traditional Bhutanese medicine (gSo-BA Rig-PA): an integrated part of the formal health care services
    Phurpa Wangchuk
    Pharmaceutical and Research Unit, Institute of Traditional Medicine Services, Ministry of Health, Thimphu, Bhutan
    Southeast Asian J Trop Med Public Health 38:161-7. 2007
  2. ncbi request reprint Hetisine-type diterpenoid alkaloids from the Bhutanese medicinal plant Aconitum orochryseum
    Phurpa Wangchuk
    Department of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
    J Nat Prod 70:1808-11. 2007
  3. doi request reprint Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW, Australia
    J Ethnopharmacol 130:559-62. 2010
  4. doi request reprint Ethnobotanical authentication and identification of Khrog-sman (Lower Elevation Medicinal Plants) of Bhutan
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia
    J Ethnopharmacol 134:813-23. 2011
  5. doi request reprint Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
    J Ethnopharmacol 137:730-42. 2011
  6. pmc Quality assurance of the university medical education, hospital services and traditional pharmaceutical products of the Bhutanese So-wa-rig-pa health care system
    Phurpa Wangchuk
    Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Townsville, QLD, 4870, Australia
    BMC Complement Altern Med 16:283. 2016
  7. pmc Medicinal plants of Dagala region in Bhutan: their diversity, distribution, uses and economic potential
    Phurpa Wangchuk
    Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, QLD, 4878, Australia
    J Ethnobiol Ethnomed 12:28. 2016
  8. pmc Contributions of medicinal plants to the Gross National Happiness and Biodiscovery in Bhutan
    Phurpa Wangchuk
    Manjong Sorig Pharmaceuticals, Ministry of Health, Thimphu, Bhutan
    J Ethnobiol Ethnomed 11:48. 2015
  9. doi request reprint A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain
    Phurpa Wangchuk
    Menjong Sorig Pharmaceuticals, Ministry of Health, Thimphu, Bhutan School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia Electronic address
    J Ethnopharmacol 150:953-9. 2013
  10. doi request reprint Inhibition of TNF-α production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
    J Ethnopharmacol 148:1013-7. 2013

Detail Information

Publications18

  1. ncbi request reprint Traditional Bhutanese medicine (gSo-BA Rig-PA): an integrated part of the formal health care services
    Phurpa Wangchuk
    Pharmaceutical and Research Unit, Institute of Traditional Medicine Services, Ministry of Health, Thimphu, Bhutan
    Southeast Asian J Trop Med Public Health 38:161-7. 2007
    ....
  2. ncbi request reprint Hetisine-type diterpenoid alkaloids from the Bhutanese medicinal plant Aconitum orochryseum
    Phurpa Wangchuk
    Department of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
    J Nat Prod 70:1808-11. 2007
    ..The structures of the new alkaloids were elucidated by spectroscopic data analysis...
  3. doi request reprint Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW, Australia
    J Ethnopharmacol 130:559-62. 2010
    ..The plant Aconitum orochryseum Stapf. (Ranunculaceae) is employed together with other plants in Bhutanese traditional medicine and is indicated for malaria-associated fever...
  4. doi request reprint Ethnobotanical authentication and identification of Khrog-sman (Lower Elevation Medicinal Plants) of Bhutan
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia
    J Ethnopharmacol 134:813-23. 2011
    ..Our study reports the botanical identification of 'Lower Elevation Medicinal Plants' and their ethnomedical uses...
  5. doi request reprint Evaluation of an ethnopharmacologically selected Bhutanese medicinal plants for their major classes of phytochemicals and biological activities
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
    J Ethnopharmacol 137:730-42. 2011
    ..We have focused our study only on seven species of these plants...
  6. pmc Quality assurance of the university medical education, hospital services and traditional pharmaceutical products of the Bhutanese So-wa-rig-pa health care system
    Phurpa Wangchuk
    Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Townsville, QLD, 4870, Australia
    BMC Complement Altern Med 16:283. 2016
    ..However, there has been no study covering the quality assurance system of BSM. Our paper addresses this information gap...
  7. pmc Medicinal plants of Dagala region in Bhutan: their diversity, distribution, uses and economic potential
    Phurpa Wangchuk
    Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, QLD, 4878, Australia
    J Ethnobiol Ethnomed 12:28. 2016
    ..It is MSP's top priority to identify an alternative collection site to ease the problem. Therefore, this study was carried out to determine whether Dagala region could potentially be an alternative collection site for MSP...
  8. pmc Contributions of medicinal plants to the Gross National Happiness and Biodiscovery in Bhutan
    Phurpa Wangchuk
    Manjong Sorig Pharmaceuticals, Ministry of Health, Thimphu, Bhutan
    J Ethnobiol Ethnomed 11:48. 2015
    ..However, no review covering the systematic evaluations of the contributions of medicinal plants and the BTM to the GNH and biodiscovery exist till date...
  9. doi request reprint A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain
    Phurpa Wangchuk
    Menjong Sorig Pharmaceuticals, Ministry of Health, Thimphu, Bhutan School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia Electronic address
    J Ethnopharmacol 150:953-9. 2013
    ..This study is to validate the ethnopharmacological uses of this plant and also identify potent antimalarial drug leads through bioassays of its crude extracts and phytochemical constituents...
  10. doi request reprint Inhibition of TNF-α production in LPS-activated THP-1 monocytic cells by the crude extracts of seven Bhutanese medicinal plants
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
    J Ethnopharmacol 148:1013-7. 2013
    ....
  11. doi request reprint An assessment of the Bhutanese traditional medicine for its ethnopharmacology, ethnobotany and ethnoquality: Textual understanding and the current practices
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, NSW 2500, Australia
    J Ethnopharmacol 148:305-10. 2013
    ..It caters to 20-30% of the daily out-patients within 49 traditional medicine units attached to 20 district modern hospitals and 29 Basic Health Units in the country...
  12. doi request reprint Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
    J Ethnopharmacol 143:310-3. 2012
    ..Corydalis dubia is used in Bhutanese traditional medicine as a febrifuge and for treating infections in the blood, liver and bile which correlate to the signs and symptoms of malarial and microbial infections...
  13. ncbi request reprint Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW, 2522, Australia
    Nat Prod Commun 7:575-80. 2012
    ..This study also identified compound 5 as potential new antimalarial lead compound...
  14. ncbi request reprint GC/GC-MS analysis, isolation and identification of bioactive essential oil components from the Bhutanese medicinal plant, Pleurospermum amabile
    Phurpa Wangchuk
    School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia
    Nat Prod Commun 8:1305-8. 2013
    ..2 (chloroquine and antifolate sensitive) and K1CB1 (multidrug resistant). They exhibited mild antibacterial activity against Bacillus subtilis. None of the test samples showed cytotoxicity...
  15. pmc Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris
    Phurpa Wangchuk
    Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia
    PLoS Negl Trop Dis 10:e0004908. 2016
    ..Encouraged by these findings, we screened four major compounds isolated from A. nubigena for their anthelmintic properties...
  16. doi request reprint Antiplasmodial agents from the Bhutanese medicinal plant Corydalis calliantha
    Phurpa Wangchuk
    Pharmaceutical and Research Unit, Department of Medical Services, Ministry of Health, Institute of Traditional Medicine Services, Thimphu, Bhutan
    Phytother Res 24:481-5. 2010
    ..The results thus support, at a molecular level, the clinical use of this plant in the Bhutanese traditional medicine and identified cheilanthifoline as a potential new antimalarial drug lead...
  17. pmc Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis
    Phurpa Wangchuk
    1 Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia 2 School of Chemistry, University of Wollongong, Wollongong, NSW, Australia
    Sci Rep 5:12845. 2015
    ..Moreover, colonic IFN-γ mRNA levels were significantly reduced in mice that received 14-O-acetylneoline compared to control mice that received TNBS alone. This alkaloid is now considered a novel anti-colitis drug lead compound. ..
  18. pmc Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms
    Phurpa Wangchuk
    Centre for Biodiscovery and Molecular Development of Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, QLD, Australia
    Sci Rep 6:32101. 2016
    ....