Liang Jen Wang

Summary

Publications

  1. doi request reprint Switching suicide methods as a predictor of completed suicide in individuals with repeated self-harm: a community cohort study in northern Taiwan
    Liang Jen Wang
    Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Aust N Z J Psychiatry 49:65-73. 2015
  2. pmc Long-term neurocognitive effects of methylphenidate in patients with attention deficit hyperactivity disorder, even at drug-free status
    Yu Shu Huang
    Department of Child Psychiatry and Sleep Center, Chang Gung MemorialHospital at Linko, Taoyuan, Taiwan
    BMC Psychiatry 12:194. 2012
  3. ncbi request reprint Zolpidem dependence and withdrawal seizure--report of two cases
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung No 200, Lane 208, Ji Jin 1st Rd, Anle District, Keelung City 204, Taiwan, ROC
    Psychiatr Danub 23:76-8. 2011
  4. pmc Low-dose memantine attenuated methadone dose in opioid-dependent patients: a 12-week double-blind randomized controlled trial
    Sheng Yu Lee
    1 Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan 2 Department of Psychiatry, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    Sci Rep 5:10140. 2015
  5. doi request reprint ALDH2 polymorphism, associated with attenuating negative symptoms in patients with schizophrenia treated with add-on dextromethorphan
    Sheng Yu Lee
    Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan Department of Psychiatry, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    J Psychiatr Res 69:50-6. 2015
  6. pmc A placebo-controlled trial of dextromethorphan as an adjunct in opioid-dependent patients undergoing methadone maintenance treatment
    Sheng Yu Lee
    Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan Dr S Y Lee Department of Psychiatry, National Cheng Kung University, Tainan, Taiwan Drs S Y Lee, P Chen, I Lee, T Y Wang, K Chen, Yang, and Lu Department of Neurology, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan Dr S L Chen Institute of Allied Health Sciences, National Cheng Kung University, Tainan, Taiwan Drs Chang and Lu Laboratory of Neurobiology, NIH NIEHS, Research Triangle Park, NC Drs Chu and S H Chen Department of Psychiatry, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan Drs Huang and Tzeng Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan Drs L J Wang, T Y Wang, and Hong Institute of Behavioral Medicine, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan Dr Lu Addiction Research Center, National Cheng Kung University, Tainan, Taiwan Dr Lu Center for Neuropsychiatric Research, National Health Research Institutes, GlaxoSmithKline
    Int J Neuropsychopharmacol 18:pyv008. 2015
  7. doi request reprint Association of salivary dehydroepiandrosterone levels and symptoms in patients with attention deficit hyperactivity disorder during six months of treatment with methylphenidate
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    Psychoneuroendocrinology 36:1209-16. 2011
  8. doi request reprint Health care service utilization and associated factors among heroin users in northern Taiwan
    Yi Chih Chen
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Taiwan
    Addict Behav 38:2635-8. 2013
  9. pmc A potential interaction between COMT and MTHFR genetic variants in Han Chinese patients with bipolar II disorder
    Liang Jen Wang
    Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Sci Rep 5:8813. 2015
  10. doi request reprint Adjunctive effects of aripiprazole on metabolic profiles: comparison of patients treated with olanzapine to patients treated with other atypical antipsychotic drugs
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    Prog Neuropsychopharmacol Biol Psychiatry 40:260-6. 2013

Collaborators

Detail Information

Publications32

  1. doi request reprint Switching suicide methods as a predictor of completed suicide in individuals with repeated self-harm: a community cohort study in northern Taiwan
    Liang Jen Wang
    Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Aust N Z J Psychiatry 49:65-73. 2015
    ..This study aimed to determine the transition of methods chosen by individuals who repeat suicide attempts, and how the switched methods of suicide attempts influence the risk of suicide death...
  2. pmc Long-term neurocognitive effects of methylphenidate in patients with attention deficit hyperactivity disorder, even at drug-free status
    Yu Shu Huang
    Department of Child Psychiatry and Sleep Center, Chang Gung MemorialHospital at Linko, Taoyuan, Taiwan
    BMC Psychiatry 12:194. 2012
    ..Whether age groups, gender or ADHD subtypes differ in neurocognitive performance during MPH treatment is also examined...
  3. ncbi request reprint Zolpidem dependence and withdrawal seizure--report of two cases
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung No 200, Lane 208, Ji Jin 1st Rd, Anle District, Keelung City 204, Taiwan, ROC
    Psychiatr Danub 23:76-8. 2011
    ..The purpose of this case report is to suggest that clinicians should pay close attention to the potential of zolpidem tolerance, abuse and dependence. The possibility of withdrawal seizure cannot be excluded especially at high doses...
  4. pmc Low-dose memantine attenuated methadone dose in opioid-dependent patients: a 12-week double-blind randomized controlled trial
    Sheng Yu Lee
    1 Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan 2 Department of Psychiatry, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    Sci Rep 5:10140. 2015
    ..039). They also had significantly lower plasma TNF-α and significantly higher TGF-β1 levels. We provide evidence of the benefit of add-on memantine in opioid dependent patients undergoing MMT. ..
  5. doi request reprint ALDH2 polymorphism, associated with attenuating negative symptoms in patients with schizophrenia treated with add-on dextromethorphan
    Sheng Yu Lee
    Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan Department of Psychiatry, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
    J Psychiatr Res 69:50-6. 2015
    ..Whether treating schizophrenia with risperidone plus add-on DM is more effective than risperidone (RISP) alone, and the association between the ALDH2 polymorphism and treatment response were investigated...
  6. pmc A placebo-controlled trial of dextromethorphan as an adjunct in opioid-dependent patients undergoing methadone maintenance treatment
    Sheng Yu Lee
    Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan Dr S Y Lee Department of Psychiatry, National Cheng Kung University, Tainan, Taiwan Drs S Y Lee, P Chen, I Lee, T Y Wang, K Chen, Yang, and Lu Department of Neurology, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan Dr S L Chen Institute of Allied Health Sciences, National Cheng Kung University, Tainan, Taiwan Drs Chang and Lu Laboratory of Neurobiology, NIH NIEHS, Research Triangle Park, NC Drs Chu and S H Chen Department of Psychiatry, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan Drs Huang and Tzeng Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan Drs L J Wang, T Y Wang, and Hong Institute of Behavioral Medicine, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan Dr Lu Addiction Research Center, National Cheng Kung University, Tainan, Taiwan Dr Lu Center for Neuropsychiatric Research, National Health Research Institutes, GlaxoSmithKline
    Int J Neuropsychopharmacol 18:pyv008. 2015
    ..In a randomized, double-blind, controlled 12 week study, we investigated whether add-on dextromethorphan reduced cytokine levels and benefitted opioid-dependent patients undergoing methadone maintenance therapy (MMT)...
  7. doi request reprint Association of salivary dehydroepiandrosterone levels and symptoms in patients with attention deficit hyperactivity disorder during six months of treatment with methylphenidate
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    Psychoneuroendocrinology 36:1209-16. 2011
    ..Whether DHEA exerts effects on neurocognitive functions as mediators or independently of MPH warrants further investigation...
  8. doi request reprint Health care service utilization and associated factors among heroin users in northern Taiwan
    Yi Chih Chen
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Taiwan
    Addict Behav 38:2635-8. 2013
    ..The findings of this study are useful references for targeting the heroin users for whom a successful intervention represents the greatest cost benefit...
  9. pmc A potential interaction between COMT and MTHFR genetic variants in Han Chinese patients with bipolar II disorder
    Liang Jen Wang
    Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Sci Rep 5:8813. 2015
    ..Our findings support preliminary evidence that the COMT and MTHFR genes interact in BP-II, and they imply the connection of both dopaminergic pathways and methylation pathways in the pathogenesis of BP-II. ..
  10. doi request reprint Adjunctive effects of aripiprazole on metabolic profiles: comparison of patients treated with olanzapine to patients treated with other atypical antipsychotic drugs
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    Prog Neuropsychopharmacol Biol Psychiatry 40:260-6. 2013
    ..A long-term, randomized, double-blind controlled design is suggested to confirm these findings...
  11. doi request reprint Risk of Mortality Among Patients Treated With Antipsychotic Medications: A Nationwide Population-Based Study in Taiwan
    Liang Jen Wang
    From the Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Department of Psychiatry, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan Institute of Statistical Science, Academia Sinica Genome and Systems Biology Degree Program, National Taiwan University and Academia Sinica Institute of Biopharmaceutical Sciences, National Yang Ming University, Taipei Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung, Taiwan Department of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX and Institute of Molecular Biology, Academia Sinica, Nankang, Taipei, Taiwan
    J Clin Psychopharmacol 36:9-17. 2016
    ..Clinicians should pay attention to the mortality risk when prescribing antipsychotic medications, particularly for the elderly and critically ill patients. ..
  12. doi request reprint Attention-deficit hyperactivity disorder, its pharmacotherapy, and the risk of developing bipolar disorder: A nationwide population-based study in Taiwan
    Liang Jen Wang
    Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Psychiatr Res 72:6-14. 2016
    ..In comparison to the control group, the ADHD group showed a significantly increased risk of developing BD (ADHD: 2.1% vs...
  13. doi request reprint Impact of negative media publicity on attention-deficit/hyperactivity disorder medication in Taiwan
    Liang Jen Wang
    Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Pharmacoepidemiol Drug Saf 25:45-53. 2016
    ..This study explores trends in attention-deficit/hyperactivity disorder (ADHD) medications in Taiwan from 2000 to 2011 and whether negative media coverage of Ritalin in January 2010 impacted ADHD prescriptions throughout the country...
  14. doi request reprint Neurocognitive effects of aripiprazole in adolescents and young adults with schizophrenia
    Chin Bin Yeh
    Chin Bin Yeh, M D, Ph D, Department of Psychiatry, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan
    Nord J Psychiatry 68:219-24. 2014
    ..The use of aripiprazole has been associated with a positive influence on mood and improved cognitive skills and social interactions; however, studies of its effects on young schizophrenic patients have been limited to active symptoms...
  15. doi request reprint Genotype variant associated with add-on memantine in bipolar II disorder
    Sheng Yu Lee
    Department of Psychiatry, National Cheng Kung University, Tainan, Taiwan
    Int J Neuropsychopharmacol 17:189-97. 2014
    ..004). We conclude that the BDNF Val66Met polymorphism influenced responses to add-on memantine by decreasing depressive symptoms in patients with BP-II. ..
  16. pmc Quetiapine fumarate augmentation for patients with a primary anxiety disorder or a mood disorder: a pilot study
    Yi Chih Chen
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    BMC Psychiatry 12:162. 2012
    ....
  17. doi request reprint Persistence of psychotic symptoms as an indicator of cognitive impairment in methamphetamine users
    Chih Ken Chen
    Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan Chang Gung University School of Medicine, Taoyuan, Taiwan
    Drug Alcohol Depend 148:158-64. 2015
    ..This study aims to ascertain whether meth users who experience persistent psychosis suffer more severe cognitive impairment than those not experiencing persistent psychosis...
  18. doi request reprint Neurocognitive effects of aripiprazole in adolescents and young adults with bipolar disorder
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, and Chang Gung University School of Medicine, Taoyuan, Taiwan
    Nord J Psychiatry 66:276-82. 2012
    ..Patients with bipolar disorder have neurocognitive impairments, which are associated with poor functional outcomes...
  19. doi request reprint Risk factors for HIV, viral hepatitis, and syphilis among heroin users in northern Taiwan
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan
    Subst Use Misuse 48:89-98. 2013
    ..The results of this study suggest that a comprehensive public health program is needed to prevent transmission of these blood-borne infections. The study's limitations are noted...
  20. doi request reprint Comorbidity of attention-deficit/hyperactivity disorder, Tourette's syndrome and bipolar I disorder in an adolescent patient with schizencephaly
    Chou Yu Yeh
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Taiwan
    Gen Hosp Psychiatry 34:702.e1-3. 2012
    ..This case report implies that the pathophysiology of psychiatric disorders, especially in young patients with multiple comorbid conditions, may be associated with abnormalities in the anatomical and functional development of the brain...
  21. doi request reprint Is Case Management Effective for Long-Lasting Suicide Prevention?
    Liang Jen Wang
    1 Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Crisis 36:194-201. 2015
    ..Case management services have been implemented in suicide prevention programs...
  22. doi request reprint Gender Differences in the Behavioral Symptoms and Neuropsychological Performance of Patients with Attention-Deficit/Hyperactivity Disorder Treated with Methylphenidate: A Two-Year Follow-up Study
    Liang Jen Wang
    1 Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Child Adolesc Psychopharmacol 25:501-8. 2015
    ....
  23. doi request reprint Neurocognitive performance and behavioral symptoms in patients with attention-deficit/hyperactivity disorder during twenty-four months of treatment with methylphenidate
    Liang Jen Wang
    1 Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Child Adolesc Psychopharmacol 25:246-53. 2015
    ..This study investigated the trends in neurocognitive function and behavioral symptoms among patients with attention-deficit/hyperactivity disorder (ADHD) during 24 months of treatment with methylphenidate in a clinical setting...
  24. doi request reprint Prescription of psychotropic drugs in patients with chronic renal failure on hemodialysis
    Chou Yu Yeh
    Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan
    Ren Fail 36:1545-9. 2014
    ..This study aimed to investigate the prevalence of the use of psychotropic drugs among patients on hemodialysis and to elucidate the factors associated with use of each class of psychotropic medication...
  25. doi request reprint The rate of fatality and demographic characteristics associated with various suicide methods: a community-based study in Northern Taiwan
    Chun yi Lee
    lt location gt Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan lt location gt
    Crisis 35:245-52. 2014
    ..Understanding lethality and risk factors of suicide methods is an initial step in suicide prevention...
  26. doi request reprint Salivary neurosteroid levels and behavioural profiles of children with attention-deficit/hyperactivity disorder during six months of methylphenidate treatment
    Liang Jen Wang
    1 Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Child Adolesc Psychopharmacol 24:336-40. 2014
    ....
  27. ncbi request reprint Is suicide mortality associated with meteorological and socio-economic factors? An ecological study in a city in Taiwan with a high suicide rate
    Ya Wen Wu
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    Psychiatr Danub 26:152-8. 2014
    ..Keelung City has the highest suicide rate in Taiwan. This study aimed to determine whether meteorological and socio-economic factors are associated with suicide mortality in Keelung City, by gender and by means of suicide...
  28. pmc Add-on memantine to valproate treatment increased HDL-C in bipolar II disorder
    Sheng Yu Lee
    Department of Psychiatry, National Cheng Kung University, Tainan, Taiwan
    J Psychiatr Res 47:1343-8. 2013
    ..020). We conclude that add-on memantine plus VPA treatment of BP-II depression increases the blood level of HDL-C even in the absence of change in affective symptoms...
  29. doi request reprint Attention-deficit hyperactivity disorder, its treatment with medication and the probability of developing a depressive disorder: A nationwide population-based study in Taiwan
    Min Jing Lee
    Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Affect Disord 189:110-7. 2016
    ....
  30. doi request reprint Factors associated with drug-related psychiatric disorders and suicide attempts among illicit drug users in Taiwan
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    Subst Use Misuse 47:1185-8. 2012
    ..These results provide useful clues for detecting drug-related psychiatric disorders and suicide among illicit drug users. The study's limitations are noted...
  31. pmc Clinical symptoms and performance on the Continuous Performance Test in children with attention deficit hyperactivity disorder between subtypes: a natural follow-up study for 6 months
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    BMC Psychiatry 11:65. 2011
    ....
  32. ncbi request reprint Active job, healthy job? Occupational stress and depression among hospital physicians in Taiwan
    Liang Jen Wang
    Department of Psychiatry, Chang Gung Memorial Hospital at Keelung, Keelung, Taiwan
    Ind Health 49:173-84. 2011
    ..This study suggests that job stress plays an important role in depression in physicians; it is necessary to pay attention to physicians at high risk of depression, as well as their work environments, for early detection and intervention...