Bojan Vrtovec

Summary

Publications

  1. pmc Renal effects of levosimendan: a consensus report
    Mehmet B Yilmaz
    Department of Cardiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Cardiovasc Drugs Ther 27:581-90. 2013
  2. pmc Accuracy of advanced versus strictly conventional 12-lead ECG for detection and screening of coronary artery disease, left ventricular hypertrophy and left ventricular systolic dysfunction
    Todd T Schlegel
    Human Adaptation and Countermeasures Division, NASA Johnson Space Center, Houston, TX, USA
    BMC Cardiovasc Disord 10:28. 2010
  3. doi request reprint Atorvastatin therapy may reduce the incidence of sudden cardiac death in patients with advanced chronic heart failure
    Bojan Vrtovec
    Advanced Heart Failure Center, Department of Cardiology, Ljubljana University Medical Center, Ljubljana, Slovenia
    J Card Fail 14:140-4. 2008
  4. doi request reprint Effects of intracoronary stem cell transplantation in patients with dilated cardiomyopathy
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center, Department of Cardiology, Ljubljana University Medical Center, Zaloska 7, Ljubljana, Slovenia
    J Card Fail 17:272-81. 2011
  5. doi request reprint Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center, Department of Cardiology, Ljubljana University Medical Center, Zaloska 7, Ljubljana, MC SI 1000, Slovenia
    Circ Res 112:165-73. 2013
  6. doi request reprint Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center B V, G P, Department of Nuclear Medicine L L, A s, and Department of Hematology M S, P C, University Medical Center Ljubljana, Ljubljana, Slovenia National Blood Transfusion Institute, Ljubljana, Slovenia D D Methodist DeBakey Heart Center, Houston, TX G T A Stanford Cardiovascular Institute F H, J C W and Department of Medicine, Division of Cardiology B V, F H, J C W, Stanford University School of Medicine, Stanford, CA
    Circulation 128:S42-9. 2013
  7. ncbi request reprint Atorvastatin therapy increases heart rate variability, decreases QT variability, and shortens QTc interval duration in patients with advanced chronic heart failure
    Bojan Vrtovec
    Division of Cardiology, Ljubljana University Medical Center, Ljubljana, Slovenia
    J Card Fail 11:684-90. 2005
  8. doi request reprint Intracoronary transplantation of CD34(+) cells is associated with improved myocardial perfusion in patients with nonischemic dilated cardiomyopathy
    Luka Lezaic
    Department for Nuclear Medicine, University Medical Centre UMC, Ljubljana, Slovenia
    J Card Fail 21:145-52. 2015
  9. doi request reprint Relation of B-type natriuretic peptide level in heart failure to sudden cardiac death in patients with and without QT interval prolongation
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center, Department of Cardiology, University Medical Center Ljubljana, Ljubljana, Slovenia
    Am J Cardiol 111:886-90. 2013
  10. doi request reprint Effects of transendocardial CD34+ cell transplantation in patients with ischemic cardiomyopathy
    Gregor Poglajen
    From the Department of Cardiology, Advanced Heart Failure and Transplantation Center G P, G Z, B V, Department of Hematology M S, P C, and Department of Cardiovascular Surgery I K, University Medical Center Ljubljana, Ljubljana, Slovenia National Blood Transfusion Institute, Ljubljana, Slovenia M C and Stanford Cardiovascular Institute, Stanford University School of Medicine, Palo Alto, CA F H, J C W, B V
    Circ Cardiovasc Interv 7:552-9. 2014

Collaborators

  • Francois Haddad
  • Gregor Poglajen
  • Vito Starc
  • Gregor Zemljic
  • Marko Cukjati
  • Branislav Radovancevic
  • Guillermo Torre-Amione
  • Todd T Schlegel
  • Ulrich P Jorde
  • Matija Jelenc
  • Ivan Knezevic
  • Misa Fister
  • Ursa Mikuz
  • Joseph C Wu
  • Jus Ksela
  • Andraž Cerar
  • Luka Lezaic
  • Jure Dolenc
  • Mehmet B Yilmaz
  • Katja Triller Vrtovec
  • Reynolds M Delgado
  • Rajko Radovancevic
  • Ivan Stojanovic
  • Matjaz Vrtovec
  • Aljaz Socan
  • Peter Cernelc
  • Petra Kolenc Peitl
  • Matjaz Sever
  • Miran Sebestjen
  • Mirta Kozelj
  • Henry Hsia
  • Tatjana Pintar
  • Anja Oman
  • Eva Hrovat
  • José C Silva Cardoso
  • Alexander Parkhomenko
  • Sebastian Rehberg
  • Sven Erik Ricksten
  • Veli Pekka Harjola
  • Istvan Edes
  • Sascha Treskatsch
  • Jos le Noble
  • Andrea Morelli
  • Francesco Fedele
  • Anders Oldner
  • Mervyn Singer
  • Markku Salmenperä
  • Gerhard Poelzl
  • Ignacio Oulego Erroz
  • John T Parissis
  • Piero Pollesello
  • Gerhard Wikstrom
  • Matti Kivikko
  • Alexandre Mebazaa
  • Elena Grossini
  • Julia Hasslacher
  • Luis M Rodríguez Fernández
  • Nanthini Palanichamy
  • Bojan Vrtotec
  • Andreja Kocijancic
  • O H Frazier
  • Cynthia D Thomas
  • Richard A Anderson
  • Aria P Yazdanbakhsh
  • Alenka Briski

Detail Information

Publications35

  1. pmc Renal effects of levosimendan: a consensus report
    Mehmet B Yilmaz
    Department of Cardiology, Cumhuriyet University School of Medicine, Sivas, Turkey
    Cardiovasc Drugs Ther 27:581-90. 2013
    ..As an example, a study is shortly to commence to assess the role of levosimendan for the prevention of acute organ dysfunction in sepsis (LeoPARDS). ..
  2. pmc Accuracy of advanced versus strictly conventional 12-lead ECG for detection and screening of coronary artery disease, left ventricular hypertrophy and left ventricular systolic dysfunction
    Todd T Schlegel
    Human Adaptation and Countermeasures Division, NASA Johnson Space Center, Houston, TX, USA
    BMC Cardiovasc Disord 10:28. 2010
    ..We hypothesized that a approximately 5-min resting 12-lead advanced ECG test ("A-ECG") that combined results from both the advanced and conventional ECG could more accurately screen for these conditions than strictly conventional ECG...
  3. doi request reprint Atorvastatin therapy may reduce the incidence of sudden cardiac death in patients with advanced chronic heart failure
    Bojan Vrtovec
    Advanced Heart Failure Center, Department of Cardiology, Ljubljana University Medical Center, Ljubljana, Slovenia
    J Card Fail 14:140-4. 2008
    ..We sought to prospectively investigate a relation between atorvastatin therapy and SCD in patients with advanced chronic heart failure...
  4. doi request reprint Effects of intracoronary stem cell transplantation in patients with dilated cardiomyopathy
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center, Department of Cardiology, Ljubljana University Medical Center, Zaloska 7, Ljubljana, Slovenia
    J Card Fail 17:272-81. 2011
    ..We investigated clinical effects of intracoronary transplantation of CD34+ cells in patients with dilated cardiomyopathy (DCM)...
  5. doi request reprint Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center, Department of Cardiology, Ljubljana University Medical Center, Zaloska 7, Ljubljana, MC SI 1000, Slovenia
    Circ Res 112:165-73. 2013
    ..CD34+ transplantation in dilated cardiomyopathy was associated with short-term improvement in left ventricular ejection fraction and exercise tolerance...
  6. doi request reprint Comparison of transendocardial and intracoronary CD34+ cell transplantation in patients with nonischemic dilated cardiomyopathy
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center B V, G P, Department of Nuclear Medicine L L, A s, and Department of Hematology M S, P C, University Medical Center Ljubljana, Ljubljana, Slovenia National Blood Transfusion Institute, Ljubljana, Slovenia D D Methodist DeBakey Heart Center, Houston, TX G T A Stanford Cardiovascular Institute F H, J C W and Department of Medicine, Division of Cardiology B V, F H, J C W, Stanford University School of Medicine, Stanford, CA
    Circulation 128:S42-9. 2013
    ..In an open-label blinded study, we compared intracoronary and transendocardial CD34(+) cell transplantation in patients with nonischemic dilated cardiomyopathy...
  7. ncbi request reprint Atorvastatin therapy increases heart rate variability, decreases QT variability, and shortens QTc interval duration in patients with advanced chronic heart failure
    Bojan Vrtovec
    Division of Cardiology, Ljubljana University Medical Center, Ljubljana, Slovenia
    J Card Fail 11:684-90. 2005
    ..Although statins decrease the incidence of ventricular arrhythmias in patients with atherosclerotic heart disease, their potential antiarrhythmic effects in heart failure remain undefined...
  8. doi request reprint Intracoronary transplantation of CD34(+) cells is associated with improved myocardial perfusion in patients with nonischemic dilated cardiomyopathy
    Luka Lezaic
    Department for Nuclear Medicine, University Medical Centre UMC, Ljubljana, Slovenia
    J Card Fail 21:145-52. 2015
    ..We investigated the effects of intracoronary transplantation of CD34(+) cells on myocardial perfusion in patients with nonischemic dilated cardiomyopathy (DCM)...
  9. doi request reprint Relation of B-type natriuretic peptide level in heart failure to sudden cardiac death in patients with and without QT interval prolongation
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center, Department of Cardiology, University Medical Center Ljubljana, Ljubljana, Slovenia
    Am J Cardiol 111:886-90. 2013
    ..006), but BNP increase was not (p = 0.32). In conclusion, a BNP increase in patients with HF was associated with an increased risk of SCD only in patients with QTc interval prolongation...
  10. doi request reprint Effects of transendocardial CD34+ cell transplantation in patients with ischemic cardiomyopathy
    Gregor Poglajen
    From the Department of Cardiology, Advanced Heart Failure and Transplantation Center G P, G Z, B V, Department of Hematology M S, P C, and Department of Cardiovascular Surgery I K, University Medical Center Ljubljana, Ljubljana, Slovenia National Blood Transfusion Institute, Ljubljana, Slovenia M C and Stanford Cardiovascular Institute, Stanford University School of Medicine, Palo Alto, CA F H, J C W, B V
    Circ Cardiovasc Interv 7:552-9. 2014
    ..We investigated the effects of transendocardial CD34(+) cell transplantation in patients with ischemic cardiomyopathy...
  11. doi request reprint Electroanatomic Properties of the Myocardium Predict Response to CD34+ Cell Therapy in Patients With Ischemic and Nonischemic Heart Failure
    Gregor Zemljic
    Advanced Heart Failure and Transplantation Center, UMC Ljubljana, Slovenia
    J Card Fail . 2016
    ..We investigated a correlation between electromechanical properties of the myocardium and response to CD34+ cell therapy in patients with chronic heart failure...
  12. pmc Efficacy of CD34+ Stem Cell Therapy in Nonischemic Dilated Cardiomyopathy Is Absent in Patients With Diabetes but Preserved in Patients With Insulin Resistance
    Bojan Vrtovec
    Advanced Heart Failure and Transplantation Center, Ljubljana University Medical Centre, Ljubljana, Slovenia Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA
    Stem Cells Transl Med 5:632-8. 2016
    ..034). Transendocardial CD34(+) cell therapy appears to be ineffective in DCM patients with diabetes. IR was associated with improved CD34(+) stem cell mobilization and a preserved clinical response to cell therapy...
  13. pmc Stem cell therapy in patients with heart failure
    Bojan Vrtovec
    Ljubljana University Medical Center, Ljubljana, Slovenia
    Methodist Debakey Cardiovasc J 9:6-10. 2013
    ..For these patients, stem cell therapies are being investigated as a safe treatment strategy for decreasing cardiac remodelling on top of conventional medical and device treatment...
  14. doi request reprint Immunologic Network and Response to Intramyocardial CD34+ Stem Cell Therapy in Patients With Dilated Cardiomyopathy
    Francois Haddad
    Stanford University School of Medicine, Stanford Cardiovascular Institute, Stanford, California Advanced Heart Failure and Transplantation Center, University Medical Center, Ljubljana, Slovenia
    J Card Fail 21:572-82. 2015
    ..Our objective was to determine whether baseline differences in circulating immunologic and nonimmunologic biomarkers may help to identify patients more likely to respond to intramyocardial injection of CD34(+)-based SCT...
  15. doi request reprint The presence of electromechanical mismatch in nonischemic dilated cardiomyopathy is associated with ventricular repolarization instability
    Ursa Mikuz
    Advanced Heart Failure and Transplantation Center, Department of Cardiology, University Medical Center, Ljubljana, Slovenia
    J Card Fail 20:891-8. 2014
    ..We analyzed electromechanical mismatch (EMM) and its relationship to ventricular repolarization in patients with nonischemic dilated cardiomyopathy (DCM)...
  16. doi request reprint Diabetes does not affect ventricular repolarization and sudden cardiac death risk in patients with dilated cardiomyopathy
    Bojan Vrtovec
    Advanced Heart Failure Center, Department of Cardiology, Ljubljana University Medical Center, Ljubljana, Slovenia
    Pacing Clin Electrophysiol 32:S146-50. 2009
    ..We studied the effects of diabetes on ventricular repolarization parameters and sudden cardiac death in patients with dilated cardiomyopathy (DCM)...
  17. doi request reprint Heart rate-guided, but not dose-guided titration of beta blockers stabilizes ventricular repolarization in patients with chronic heart failure
    Misa Fister
    Advanced Heart Failure and Transplantation Center, UMC, Ljubljana, Slovenia
    J Electrocardiol 49:579-86. 2016
    ..We compared the effects of heart rate-guided and dose-guided beta-blocker titration strategies on QT variability in patients with chronic heart failure (CHF)...
  18. doi request reprint Increased red cell distribution width is associated with poor stem cell mobilization in patients with advanced chronic heart failure
    Gregor Poglajen
    A Department of Cardiology, Advanced Heart Failure and Transplantation Center, University Medical Center Ljubljana, Ljubljana, Slovenia
    Biomarkers 20:365-70. 2015
    ..Increased RDW was the only independent predictor of poor CD34(+) stem cell mobilization on multivariable analysis and may serve as a biomarker of poor stem cell mobilization in CHF patients. ..
  19. doi request reprint The effects of levosimendan on renal function early after heart transplantation: results from a pilot randomized trial
    Ivan Knezevic
    Advanced Heart Failure and Transplantation Center, UMC, Ljubljana, Slovenia
    Clin Transplant 28:1105-11. 2014
    ..We evaluated the effects of a levosimendan (LS)-based strategy compared with standard inotropic therapy on renal function in heart transplantation...
  20. ncbi request reprint Commentary: is totipotency of a human cell a sufficient reason to exclude its patentability under the European law?
    Katja Triller Vrtovec
    Max Planck Institute for Intellectual Property, Competition and Tax Law, Munchen, Germany
    Stem Cells 25:3026-8. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  21. doi request reprint LVAD as a Bridge to Heart Transplantation in a Patient with Left Ventricular Noncompaction Cardiomyopathy and Advanced Heart Failure
    Andraž Cerar
    Department of Cardiology, Advanced Heart Failure and Transplantation Center, University Medical Center, Ljubljana, Slovenia
    Heart Surg Forum 19:E128-30. 2016
    ..We report a case of a 29-year-old patient with LVNC and advanced refractory heart failure, who was successfully bridged to heart transplantation using a long-term continuous-flow left ventricular assist device. ..
  22. doi request reprint Trimetazidine shortens QTc interval in patients with ischemic heart failure
    Gregor Zemljic
    Advanced Heart Failure and Transplantation Center, Division of Cardiology, Ljubljana University Medical Center, Ljubljana, Slovenia
    J Cardiovasc Pharmacol Ther 15:31-6. 2010
    ..We analyzed the effects of trimetazidine on QTc interval in patients with ischemic heart failure...
  23. doi request reprint Pulmonary hypertension in patients with advanced heart failure is associated with increased levels of interleukin-6
    Jure Dolenc
    Department of Cardiology, University Medical Centre Ljubljana, Ljubljana, Slovenia
    Biomarkers 19:385-90. 2014
    ..Inflammatory, endothelial and neurohormonal biomarkers are involved in heart failure (HF) and pulmonary hypertension (PH) pathogenesis...
  24. ncbi request reprint Levosimendan improves renal function in patients with advanced chronic heart failure awaiting cardiac transplantation
    Gregor Zemljic
    Advanced Heart Failure and Transplantation Center, Division of Cardiology, Ljubljana University Medical Center, Ljubljana, Slovenia
    J Card Fail 13:417-21. 2007
    ..Long-term impact of levosimendan on renal function remains undefined. Prospectively, we evaluated effects of levosimendan on renal function in patients with advanced chronic heart failure awaiting cardiac transplantation...
  25. ncbi request reprint Chromium supplementation shortens QTc interval duration in patients with type 2 diabetes mellitus
    Matjaz Vrtovec
    Ljubljana University Medical Centre, Ljubljana, Slovenia
    Am Heart J 149:632-6. 2005
    ..We investigated the potential effects of chromium supplementation on QTc interval duration in type 2 diabetic patients...
  26. ncbi request reprint Coronary artery disease alters ventricular repolarization dynamics in type 2 diabetes
    Bojan Vrtovec
    Division of Cardiology, Ljubljana University Medical Center, Ljubljana, Slovenia
    Pacing Clin Electrophysiol 28:S178-81. 2005
    ..18 +/- 7.45 ms versus 10.22 +/- 5.35 ms; P = 0.82). CAD increases VRD in patients with type 2 diabetes. Therefore, changes in ventricular repolarization in diabetic patients may be due to silent CAD rather than due to diabetes per se...
  27. doi request reprint Prolonged circulatory support with short-term continuous-flow pump in an infant with end-stage heart failure
    Ivan Knezevic
    Department of Cardiovascular Surgery, University Medical Center Ljubljana, Ljubljana, Slovenia
    Transpl Int . 2017
    ..This article is protected by copyright. All rights reserved...
  28. doi request reprint Mitral regurgitation and axial flow left ventricular assist device: a computer simulation study
    Matija Jelenc
    Department of Cardiovascular Surgery, University Medical Centre Ljubljana, Ljubljana, Slovenia
    ASAIO J 59:405-9. 2013
    ..According to the computer model, LVAD support decreases mitral regurgitation. Furthermore, regurgitant volume has a smaller impact on the right ventricular afterload when compared with a heart without LVAD support. ..
  29. ncbi request reprint End-organ function in patients on long-term circulatory support with continuous- or pulsatile-flow assist devices
    Branislav Radovancevic
    Center for Cardiac Support, Texas Heart Institute at St Luke s Episcopal Hospital, Houston, Texas 77225 0345, USA
    J Heart Lung Transplant 26:815-8. 2007
    ..Limited data exist about the long-term effects of continuous-flow vs pulsatile-flow left ventricular assist devices (LVADs) on end-organ function...
  30. ncbi request reprint Brain natriuretic peptide levels and response to cardiac resynchronization therapy in heart failure patients
    Reynolds M Delgado
    Center for Cardiac Support, Texas Heart Institute at St Luke s Episcopal Hospital, Houston, TX 77225 0345, USA
    Congest Heart Fail 12:250-3. 2006
    ..046. A rise in BNP levels was associated with poor response (death or need for transplantation or left ventricular assist device and impaired long-term outcome), which makes it a good predictor to identify such patients...
  31. ncbi request reprint Statin-associated QTc interval shortening as prognostic indicator in heart transplant recipients
    Bojan Vrtovec
    Department of Cardiac Transplantation, Texas Heart Institute at St Luke s Episcopal Hospital, Houston, Texas 77225 0345, USA
    J Heart Lung Transplant 25:234-6. 2006
    ..Statin-associated QTc shortening thus appears to be a favorable prognostic sign after transplantation...
  32. ncbi request reprint Survival, graft atherosclerosis, and rejection incidence in heart transplant recipients treated with statins: 5-year follow-up
    Ivan Stojanovic
    Cardiopulmonary Transplantation Service, Texas Heart Institute at St Luke s Episcopal Hospital, Houston, Texas 77225 0345, USA
    J Heart Lung Transplant 24:1235-8. 2005
    ..Few studies have examined the long-term benefits of statin treatment in heart transplant recipients...
  33. ncbi request reprint Factors predicting 10-year survival after heart transplantation
    Branislav Radovancevic
    Department of Cardiopulmonary Transplantation, Texas Heart Institute at St Luke s Episcopal Hospital, Houston, TX 77225, USA
    J Heart Lung Transplant 24:156-9. 2005
    ..We sought to identify factors predictive of long-term (>10-year) survival in heart transplant (HTx) recipients...
  34. ncbi request reprint Outcomes in patients with low left ventricular ejection fraction after heart transplantation
    Branislav Radovancevic
    Cardiopulmonary Transplantation Service, Texas Heart Institute at St Luke s Episcopal Hospital, Houston, TX 77225 0345, USA
    Eur J Cardiothorac Surg 23:743-7. 2003
    ..We reviewed our database in order to determine outcomes in patients with low EF after HT and to identify a subset of patients who would benefit from immediate retransplantation...
  35. ncbi request reprint Prolonged QTc interval and high B-type natriuretic peptide levels together predict mortality in patients with advanced heart failure
    Bojan Vrtovec
    Heart Failure Center, Texas Heart Institute at St Luke s Episcopal Hospital, PO Box 20345, MC 2 114, Houston, Tex 77225 0345, USA
    Circulation 107:1764-9. 2003
    ..To better understand it, we analyzed the QTc interval duration in patients with heart failure with high B-type natriuretic peptide (BNP) levels and analyzed the combined prognostic impact of prolonged QTc and elevated BNP...