Fabien B Vincent

Summary

Publications

  1. doi request reprint Antidrug antibodies (ADAb) to tumour necrosis factor (TNF)-specific neutralising agents in chronic inflammatory diseases: a real issue, a clinical perspective
    Fabien B Vincent
    B lymphocyte, BAFF and Autoimmunity Laboratory, Department of Immunology, Monash University, Level 2, AMREP Building, 89 Commercial Road, Melbourne, Victoria 3004, Australia
    Ann Rheum Dis 72:165-78. 2013
  2. doi request reprint BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus
    Fabien B Vincent
    Department of Immunology, Monash University, Central Clinical School, Alfred Medical Research and Education Precinct AMREP, Melbourne, Victoria, Australia
    Immunol Cell Biol 90:293-303. 2012
  3. doi request reprint BAFF-driven autoimmunity requires CD19 expression
    Kirsten A Fairfax
    Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia The Walter and Eliza Hall Institute of Medical Research, Molecular Medicine Division, 1G Royal Parade, Melbourne 3052, Australia The Department of Experimental Medicine, University of Melbourne, Parkville, Victoria 3052, Australia
    J Autoimmun 62:1-10. 2015
  4. doi request reprint Roles of ligands from the TNF superfamily in B cell development, function, and regulation
    William A Figgett
    Department of Immunology, Monash University, Central Clinical School, Alfred Medical Research and Education Precinct AMREP, Commercial Road, Melbourne, Victoria 3004, Australia
    Semin Immunol 26:191-202. 2014
  5. doi request reprint The BAFF/APRIL system in SLE pathogenesis
    Fabien B Vincent
    Department of Immunology, Monash University, Central Clinical School, Alfred Medical Research and Education Precinct AMREP, 89 Commercial Road, Melbourne, VIC 3004, Australia
    Nat Rev Rheumatol 10:365-73. 2014

Collaborators

  • William A Figgett
  • Kirsten A Fairfax
  • Fabienne Mackay
  • Melanie Lepage
  • Margaret L Hibbs
  • Pin Shie Quah
  • Evelyn Tsantikos
  • Damien Saulep-Easton

Detail Information

Publications6

  1. doi request reprint Antidrug antibodies (ADAb) to tumour necrosis factor (TNF)-specific neutralising agents in chronic inflammatory diseases: a real issue, a clinical perspective
    Fabien B Vincent
    B lymphocyte, BAFF and Autoimmunity Laboratory, Department of Immunology, Monash University, Level 2, AMREP Building, 89 Commercial Road, Melbourne, Victoria 3004, Australia
    Ann Rheum Dis 72:165-78. 2013
    ..Such an approach could improve chronic inflammatory disease management toward a personalized and more cost-effective approach...
  2. doi request reprint BAFF and innate immunity: new therapeutic targets for systemic lupus erythematosus
    Fabien B Vincent
    Department of Immunology, Monash University, Central Clinical School, Alfred Medical Research and Education Precinct AMREP, Melbourne, Victoria, Australia
    Immunol Cell Biol 90:293-303. 2012
    ..We will also review promising therapies presently in clinical trials targeting innate immunity, which are likely to revolutionize SLE management towards a personalized and targeted therapy approach...
  3. doi request reprint BAFF-driven autoimmunity requires CD19 expression
    Kirsten A Fairfax
    Faculty of Medicine, Nursing and Health Sciences, Department of Immunology, Central Clinical School, Monash University, Commercial Rd, Melbourne 3004, Australia The Walter and Eliza Hall Institute of Medical Research, Molecular Medicine Division, 1G Royal Parade, Melbourne 3052, Australia The Department of Experimental Medicine, University of Melbourne, Parkville, Victoria 3052, Australia
    J Autoimmun 62:1-10. 2015
    ..Loss of the majority of innate-like B cells was able to protect BAFF-Tg mice from developing disease, so we can now conclude that autoimmunity induced by excessive BAFF production requires B1b B cells and CD19 signaling. ..
  4. doi request reprint Roles of ligands from the TNF superfamily in B cell development, function, and regulation
    William A Figgett
    Department of Immunology, Monash University, Central Clinical School, Alfred Medical Research and Education Precinct AMREP, Commercial Road, Melbourne, Victoria 3004, Australia
    Semin Immunol 26:191-202. 2014
    ..As a result, inhibitors of a number of TNF ligands have been tested in the clinic, with some becoming very successful approved treatments alleviating B cell-mediated pathologies. ..
  5. doi request reprint The BAFF/APRIL system in SLE pathogenesis
    Fabien B Vincent
    Department of Immunology, Monash University, Central Clinical School, Alfred Medical Research and Education Precinct AMREP, 89 Commercial Road, Melbourne, VIC 3004, Australia
    Nat Rev Rheumatol 10:365-73. 2014
    ..The role of a related cytokine, TNF ligand superfamily member 13 (also known as a proliferation-inducing ligand [APRIL]) in SLE is much less well understood, and hence this review focuses on BAFF. ..